CN106414485A8 - 人工活化的毒性肽 - Google Patents

人工活化的毒性肽 Download PDF

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Publication number
CN106414485A8
CN106414485A8 CN201580029683.6A CN201580029683A CN106414485A8 CN 106414485 A8 CN106414485 A8 CN 106414485A8 CN 201580029683 A CN201580029683 A CN 201580029683A CN 106414485 A8 CN106414485 A8 CN 106414485A8
Authority
CN
China
Prior art keywords
toxic peptide
artificial activation
new
toxic
artificial
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201580029683.6A
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English (en)
Other versions
CN106414485A (zh
Inventor
R.M.肯尼迪
鲍林
A.R.卡尔森
C.L.富恩
A.M.哈斯
B.A.施泰因鲍夫
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vestaron Corp
Original Assignee
Vestaron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vestaron Corp filed Critical Vestaron Corp
Priority to CN202010133478.7A priority Critical patent/CN111233992A/zh
Publication of CN106414485A publication Critical patent/CN106414485A/zh
Publication of CN106414485A8 publication Critical patent/CN106414485A8/zh
Pending legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43518Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from spiders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/02Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
    • A01N25/04Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/44Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
    • A01N37/46N-acyl derivatives
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/10Animals; Substances produced thereby or obtained therefrom
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/50Isolated enzymes; Isolated proteins

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Insects & Arthropods (AREA)
  • Genetics & Genomics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Dispersion Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

描述了对某些毒性肽进行人工诱导的转化以生成那些肽的不同形式和原始肽的新型且可用的衍生物二者,这两者本身有用且可用作可用于制备其它重要化合物的新型化合物和新型稳定中间体。
CN201580029683.6A 2014-04-04 2015-04-03 人工活化的毒性肽 Pending CN106414485A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202010133478.7A CN111233992A (zh) 2014-04-04 2015-04-03 人工活化的肽

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461975147P 2014-04-04 2014-04-04
US61/975,147 2014-04-04
PCT/US2015/024334 WO2015154020A1 (en) 2014-04-04 2015-04-03 Artificially activated toxic peptides

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN202010133478.7A Division CN111233992A (zh) 2014-04-04 2015-04-03 人工活化的肽

Publications (2)

Publication Number Publication Date
CN106414485A CN106414485A (zh) 2017-02-15
CN106414485A8 true CN106414485A8 (zh) 2017-07-04

Family

ID=53008855

Family Applications (2)

Application Number Title Priority Date Filing Date
CN202010133478.7A Pending CN111233992A (zh) 2014-04-04 2015-04-03 人工活化的肽
CN201580029683.6A Pending CN106414485A (zh) 2014-04-04 2015-04-03 人工活化的毒性肽

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CN202010133478.7A Pending CN111233992A (zh) 2014-04-04 2015-04-03 人工活化的肽

Country Status (11)

Country Link
US (2) US20170121377A1 (zh)
EP (1) EP3125694A1 (zh)
JP (2) JP6800752B2 (zh)
KR (2) KR102444555B1 (zh)
CN (2) CN111233992A (zh)
AU (2) AU2015240516C1 (zh)
BR (1) BR112016023040A2 (zh)
CA (1) CA2944334A1 (zh)
IL (1) IL248051B (zh)
MX (3) MX2016012546A (zh)
WO (1) WO2015154020A1 (zh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10743535B2 (en) 2017-08-18 2020-08-18 H&K Solutions Llc Insecticide for flight-capable pests

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1150683B (de) * 1960-07-28 1963-06-27 Ciba Geigy Verfahren zur Herstellung von Petidhydraziden
US4179337A (en) 1973-07-20 1979-12-18 Davis Frank F Non-immunogenic polypeptides
WO1995018186A1 (en) * 1993-12-28 1995-07-06 Arqule Partners, L.P. Modular design and synthesis of aminimide containing molecules
FI98513C (fi) * 1995-06-09 1997-07-10 Cultor Oy Kasvien satotuloksen parantaminen
IL123506A (en) * 1995-09-01 2004-12-15 Corixa Corp Polypeptide compounds and preparations for immunotherapy and diagnosis of tuberculosis
JP2003111595A (ja) * 2001-06-25 2003-04-15 Kyogo Ito 腫瘍抗原
ES2318576T3 (es) * 2004-11-04 2009-05-01 University Of Connecticut Polipeptidos insecticidas y procedimientos para su uso.
WO2008020827A2 (en) * 2005-08-01 2008-02-21 Biogen Idec Ma Inc. Altered polypeptides, immunoconjugates thereof, and methods related thereto
EP2167963B1 (en) * 2007-05-23 2019-04-17 Ventana Medical Systems, Inc. Polymeric carriers for immunohistochemistry and in situ hybridization
SI2334177T1 (sl) 2008-10-01 2016-08-31 Vestaron Corporation Peptidna toksinska formulacija
CN102038006B (zh) * 2010-12-15 2013-03-20 天津理工大学 一种苏云金杆菌杀虫蛋白和芽胞吸附复合剂型的制备方法
HUE038172T2 (hu) * 2011-05-27 2018-09-28 Amicus Therapeutics Inc Eljárások célzó peptidek rekombináns lizoszómális enzimekre történõ kapcsolására lizoszómális tárolási betegségek javított kezelésében

Also Published As

Publication number Publication date
IL248051A0 (en) 2016-11-30
CN106414485A (zh) 2017-02-15
KR20220131354A (ko) 2022-09-27
KR102643502B1 (ko) 2024-03-06
BR112016023040A2 (pt) 2018-01-16
JP2020180160A (ja) 2020-11-05
MX2016012546A (es) 2017-04-27
AU2015240516C1 (en) 2019-04-11
MX2021015198A (es) 2022-01-18
AU2015240516A1 (en) 2016-10-27
WO2015154020A1 (en) 2015-10-08
MX2022010854A (es) 2022-10-07
AU2019201898B2 (en) 2021-02-11
US20200181212A1 (en) 2020-06-11
JP6800752B2 (ja) 2020-12-16
IL248051B (en) 2020-04-30
JP2017512821A (ja) 2017-05-25
EP3125694A1 (en) 2017-02-08
US20170121377A1 (en) 2017-05-04
CA2944334A1 (en) 2015-10-08
AU2019201898A1 (en) 2019-04-11
CN111233992A (zh) 2020-06-05
JP7143371B2 (ja) 2022-09-28
KR102444555B1 (ko) 2022-09-21
KR20160141804A (ko) 2016-12-09
AU2015240516B2 (en) 2018-12-20

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
CI01 Publication of corrected invention patent application

Correction item: Priority

Correct: 61/975,147 2014.04.04 US

Number: 07

Volume: 33

CI01 Publication of corrected invention patent application
CI02 Correction of invention patent application

Correction item: Priority

Correct: 61/975,147 2014.04.04 US

Number: 07

Page: The title page

Volume: 33

CI02 Correction of invention patent application