CN106377713A - Traditional Chinese medicinal compound preparation for treating herpes zoster - Google Patents
Traditional Chinese medicinal compound preparation for treating herpes zoster Download PDFInfo
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- CN106377713A CN106377713A CN201611013861.9A CN201611013861A CN106377713A CN 106377713 A CN106377713 A CN 106377713A CN 201611013861 A CN201611013861 A CN 201611013861A CN 106377713 A CN106377713 A CN 106377713A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/646—Arachnids, e.g. spiders, scorpions, ticks or mites
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/708—Rheum (rhubarb)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/90—Smilacaceae (Catbrier family), e.g. greenbrier or sarsaparilla
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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Abstract
The invention discloses a traditional Chinese medicinal compound preparation for treating herpes zoster. The traditional Chinese medicinal compound preparation is characterized in that crude drugs are prepared from the following components by weight: scorpion, rhizoma smilacis glabrae, radix et rhizoma rhei, rhizoma polygoni cuspidate, calamine and sodium sulfate. With the adoption of the compound preparation, the scorpion, the rhizoma smilacis glabrae, the radix et rhizoma rhei and the rhizoma polygoni cuspidate are used as main drugs for calming endogenous wind and relieving muscular spasm, counteracting toxic substances and eliminating stagnation, activating meridians to stop pain, activating blood and removing blood stasis, and clearing damp heat; the drugs are combined to realize the effects of relieving pain and inflammation. The calamine and the sodium sulfate are used for astringing dampness, relieving itching and astringing sores, decreasing swelling to relieve pain, promoting the absorption of blister and relieving the pain of a patient. The traditional Chinese medicinal compound preparation has the advantages of clearing heat and removing toxicity, astringing dampness and sores, decreasing swelling to relieve pain, realizing a remarkable treatment effect and the like.
Description
Technical field
The present invention relates to Chinese medicine preparation, specifically a kind of compound Chinese medicinal preparation of herpes zoster.
Background technology
Herpes zoster is commonly encountered diseases and the frequently-occurring disease of department of dermatologry, is the infringement nerve being caused by varicella zoster viruss
This innervation area produce distinctive segmental skin lesion, be mainly shown as on the basis of edematous erythema in many clusters distributions
Cybotaxises papulovesicle and vesicle, to Semen phaseoli radiati size, tonic vesicle wall is shinny for foxtail millet grain, and the transparent clarification of bleb liquid helps distribution in unilateral band, pain
Pain substantially has a strong impact on the quality of life of patient, or even the patient having also leaves post herpetic neuralgia.Primary disease is in oral antiviral medicine
Coordinate medicine for external use while thing, mitigate the pain of patient, promote the shrivelled of vesicle and absorb, shorten the course of disease. just have one in Chinese medicine
Have and hold back wet receipts skin ulcer, the effect kind of anti-inflammatory analgetic, by external through disease institute, rapid-action, reaching mitigation patient's pain of curing the disease
Bitter purpose.
Content of the invention
It is an object of the invention to solution the deficiencies in the prior art, a kind of heat-clearing and toxic substances removing is provided, holds back wet receipts skin ulcer, subside a swelling and stop
Bitterly, therapeutic effect significantly treats the compound Chinese medicinal preparation of herpes zoster.
The technical solution adopted for the present invention to solve the technical problems is：
A kind of compound Chinese medicinal preparation treating herpes zoster is it is characterised in that crude drug is by following component structure by weight ratio
Become：Scorpio 15-25 g, Rhizoma Smilacis Glabrae 20-40g, Radix Et Rhizoma Rhei 15-25g, Rhizoma Polygoni Cuspidati 15-25g, Calamina 15-25g and Natrii Sulfas 10-20g group
Become.
Preferably：Crude drug of the present invention is to be made up of following component by weight ratio：Scorpio 20 g, Rhizoma Smilacis Glabrae 30g, Radix Et Rhizoma Rhei
20g, Rhizoma Polygoni Cuspidati 20g, Calamina 20g and Natrii Sulfas 15g composition.
The manufacture method of the present invention：Scorpio, Rhizoma Smilacis Glabrae, Radix Et Rhizoma Rhei, Rhizoma Polygoni Cuspidati, Calamina and Natrii Sulfas are got it filled mixing all by proportioning
Even, pulverize 120 mesh sieves, routinely can be made into powder standby.
Using method：Take appropriate powder mature vinegar to be tuned into pasty state according to skin lesion size during use, be coated in outward erythema
At vesicle, daily 3-4 time.First original medicine is removed with 0.9% normal saline every time before medication.
The present invention is because using above-mentioned compound preparation, with Scorpio, Rhizoma Smilacis Glabrae, Radix Et Rhizoma Rhei, Rhizoma Polygoni Cuspidati is principal agent endogenous wind stopping spasmolytic, counteracting toxic substances
Eliminating stagnation, removing obstruction in the collateral to relieve pain, blood circulation promoting and blood stasis dispelling, let out clearly damp and hot, all medicines combine reach anti-inflammatory analgetic effect.Calamina, Natrii Sulfas, removing dampness is antipruritic
Sore, reducing swelling and alleviating pain, promote vesicle absorption, mitigate patient pain, have heat-clearing and toxic substances removing, hold back wet receipts skin ulcer, reducing swelling and alleviating pain,
The advantages of therapeutic effect is notable.
Specific embodiment
With reference to specific embodiment, the present invention will be described.
A kind of compound Chinese medicinal preparation treating herpes zoster is it is characterised in that crude drug is by following component by weight ratio
Constitute：Scorpio 15-25 g, Rhizoma Smilacis Glabrae 20-40g, Radix Et Rhizoma Rhei 15-25g, Rhizoma Polygoni Cuspidati 15-25g, Calamina 15-25g and Natrii Sulfas 10-20g
Composition.
Preferably：Crude drug of the present invention is to be made up of following component by weight ratio：Scorpio 20 g, Rhizoma Smilacis Glabrae 30g, Radix Et Rhizoma Rhei
20g, Rhizoma Polygoni Cuspidati 20g, Calamina 20g and Natrii Sulfas 15g composition.
The manufacture method of the present invention：Scorpio, Rhizoma Smilacis Glabrae, Radix Et Rhizoma Rhei, Rhizoma Polygoni Cuspidati, Calamina and Natrii Sulfas are got it filled mixing all by proportioning
Even, pulverize 120 mesh sieves, routinely can be made into powder standby.
The present invention avoids：The skin being grievously injured ulceration the infected.
The clinical efficacy for the treatment of herpes zoster is summarized：
First, physical data
Through the treatment to 78 patients, disease time 2-10 days, the age is from 22-69 year.Enter to organize skin lesion portion all not infect, suffer from
Person does not have serious systemic disease（Diabetes, pulmonary heart disease, heart disease）And disease of immune system.
2nd, diagnostic criteria
Reference《Clinical dermatology》Fourth edition, the 300-303 page diagnostic criteria.
3rd, using method
Take appropriate powder mature vinegar to be tuned into pasty state according to skin lesion size during use, be coated in outward at erythema vesicle, daily 3-4
Secondary.First original medicine is removed with 0.9% normal saline every time before medication.
4th, efficacy assessment standard：
Improvement erythema disappears, and vesicle is shrivelled, occasionally has vesicle rotten to the corn, pain substantially mitigates.
Recovery from illness erythema disappears, the completely shrivelled incrustation of vesicle, and pain disappears.
5th, therapeutic effect
Carry out judged result for a course for the treatment of within 10 days.Take a turn for the better, recovery from illness broadly falls into clinical effective.
In 78 patients, take a turn for the better 47, fully recover 31, effective percentage 100%.
Contraindication：Cutaneous lesion the infected.
6th, model case
1st, Guo patient so-and-so, man, 25 years old, address Weihai City hot spring town, erythema, vesicle pain occur outside 3 days front left pleurobranch, come me
Institute goes to a doctor, and is diagnosed as herpes zoster, oral antiviral medicine and external external application Chinese medicine of the present invention compound preparation, future trouble coated by medicine for external use
Person's pain is relieved, continuous application 7 days, and erythra forms a scab completely, and part incrustation comes off, and substantially painless, patient does not take
Analgesic.
2 patient poplars, female, 36 years old, address Weihai mayor peak, outside the breast of right side, right shoulder erythema vesicle pain 5 days, come
Our hospital goes to a doctor, and is diagnosed as herpes zoster, oral antiviral medicine and external external application Chinese medicine of the present invention compound preparation, after medicine for external use is coated
Patient pain is relieved, continuous application 10 days, and erythra all comes off after forming a scab completely, substantially painless, and patient does not take
Analgesic.
3 patient aperture so-and-so, man, 56 years old, address Weihai City Bo Yu town, outside the abdomen of right side, erythema vesicle pain 10 days, come
Our hospital goes to a doctor, and is diagnosed as herpes zoster, oral antiviral medicine and external external application Chinese medicine of the present invention compound preparation, after medicine for external use is coated
Patient pain is relieved, continuous application 10 days, and erythra forms a scab completely, and part incrustation comes off, and occasionally has pain, patient does not take
Analgesic.
Prescription solution in the present invention is:
Scorpio:Endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain, modern experimental research has shown that：Scorpion venom to Encelialgia, skin scorch pain and
Nervi trigeminus induction cortical potential has stronger inhibitory action；Rhizoma Smilacis Glabrae：Removing toxic substances, dehumidifying, sharp joint, cure mainly：Treat furuncle, carbuncle
Swollen, scrofula, muscles and bones contraction pain, tinea pedis etc.,《The southern regions of the Yunnan Province book on Chinese herbal medicine》Red and swollen for big skin infection can be controlled, do not become i.e. indiscriminate, Rhizoma Smilacis Glabrae, is smalls, good
The record that vinegar dresses.Radix Et Rhizoma Rhei：Heat and toxic materials clearing away, eliminating fire and detoxication, blood circulation promoting and blood stasis dispelling, let out clearly damp and hot, modern study proves, this product has to be led
Rush down, function of gallbladder promoting, liver protection, antiulcer, antibacterial, the effect such as antiviral.Rhizoma Polygoni Cuspidati：Heat-clearing and toxic substances removing, promoting the function of the gallbladder to alleviate jaundice, expelling wind and removing dampness, dissipating blood stasis are fixed
Bitterly,《Gather medicinal herbs record in the south of the Five Ridges》Record energy treating snakebite, impetigo, stop loss the pain of injury.Calamina：Removing toxic substances improving acuity of vision and removing nebula, the antipruritic sore of removing dampness,
《Product converge essence will》Record dresses external and controls bottom eczema.Now it is widely applied to department of dermatologry, control as anti-corrosion, convergence, protective agent
Treat scytitiss.Natrii Sulfas：Purging heat to relax the bowels, moistening for dryness and softening hard mass, reducing swelling and alleviating pain, infected wound externally used solution soak, there is detumescence and stop
The effect of pain.
The present invention is because using above-mentioned compound preparation, with Scorpio, Rhizoma Smilacis Glabrae, Radix Et Rhizoma Rhei, Rhizoma Polygoni Cuspidati is principal agent endogenous wind stopping spasmolytic, counteracting toxic substances
Eliminating stagnation, removing obstruction in the collateral to relieve pain, blood circulation promoting and blood stasis dispelling, let out clearly damp and hot, all medicines combine reach anti-inflammatory analgetic effect.Calamina, Natrii Sulfas, removing dampness is antipruritic
Sore, reducing swelling and alleviating pain, promote vesicle absorption, mitigate patient pain, have heat-clearing and toxic substances removing, hold back wet receipts skin ulcer, reducing swelling and alleviating pain,
The advantages of therapeutic effect is notable.
Claims (2)
1. a kind of compound Chinese medicinal preparation treating herpes zoster is it is characterised in that crude drug is by following component structure by weight ratio
Become：Scorpio 15-25g, Rhizoma Smilacis Glabrae 20-40g, Radix Et Rhizoma Rhei 15-25g, Rhizoma Polygoni Cuspidati 15-25g, Calamina 15-25g and Natrii Sulfas 10-20g group
Become.
2. a kind of compound Chinese medicinal preparation treating herpes zoster according to claim 1 is it is characterised in that crude drug is by weight
Amount proportioning is to be made up of following component：Scorpio 20g, Rhizoma Smilacis Glabrae 30g, Radix Et Rhizoma Rhei 20g, Rhizoma Polygoni Cuspidati 20g, Calamina 20g and Natrii Sulfas 15g group
Become.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611013861.9A CN106377713A (en) | 2016-11-18 | 2016-11-18 | Traditional Chinese medicinal compound preparation for treating herpes zoster |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611013861.9A CN106377713A (en) | 2016-11-18 | 2016-11-18 | Traditional Chinese medicinal compound preparation for treating herpes zoster |
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| CN106377713A true CN106377713A (en) | 2017-02-08 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201611013861.9A Pending CN106377713A (en) | 2016-11-18 | 2016-11-18 | Traditional Chinese medicinal compound preparation for treating herpes zoster |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107715012A (en) * | 2017-10-13 | 2018-02-23 | 广西中医药大学 | A kind of strong drug composition for treating post-herpetic neuralgia |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101822737A (en) * | 2009-03-05 | 2010-09-08 | 朱运喜 | Traditional Chinese medicine composition for externally treating herpes zoster and preparation method thereof |
| CN104940369A (en) * | 2015-07-03 | 2015-09-30 | 赵德欣 | External use traditional Chinese medicine composition for treating herpes zoster and preparation method thereof |
-
2016
- 2016-11-18 CN CN201611013861.9A patent/CN106377713A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101822737A (en) * | 2009-03-05 | 2010-09-08 | 朱运喜 | Traditional Chinese medicine composition for externally treating herpes zoster and preparation method thereof |
| CN104940369A (en) * | 2015-07-03 | 2015-09-30 | 赵德欣 | External use traditional Chinese medicine composition for treating herpes zoster and preparation method thereof |
Non-Patent Citations (3)
| Title |
|---|
| 刘东汉: "《刘东汉危重疑难病诊疗经验》", 30 June 2014 * |
| 王志强 等: "虎杖擦剂治疗皮肤科带状疱疹128例临床疗效分析", 《中国实用医药》 * |
| 田锐: "蜈蝎散外用治疗带状疱疹48例", 《新中医》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107715012A (en) * | 2017-10-13 | 2018-02-23 | 广西中医药大学 | A kind of strong drug composition for treating post-herpetic neuralgia |
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Application publication date: 20170208 |