CN104940369A - External use traditional Chinese medicine composition for treating herpes zoster and preparation method thereof - Google Patents
External use traditional Chinese medicine composition for treating herpes zoster and preparation method thereof Download PDFInfo
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Abstract
The invention relates to an external use traditional Chinese medicine composition for treating herpes zoster and a preparation method thereof. Each dose of the composition is prepared from, by weight, 28-32 g of rheum officinale, 29-31 g of golden cypress, 27-33 g of scutellaria baicalensis, 28-32 g of polygonum cuspidatum, 27-34 g of lithospermum, 25-35 g of sanguisorba officinalis, 28-30 g of pericarpium papaveris and 4-8 g of borneol. The crude medicine is placed in a crock, 700 g of sesame oil is firstly added to the crock, the crock is sealed, and the crude medicine is immersed for three days; the crude medicine is decocted with slow fire, and the crude medicine is decocted to be withered and yellow; medicine residues are filtered out finally, and medicine oil is obtained; the crude medicine is matched and complements one another for mutual use, and the external use traditional Chinese medicine composition has the effects of removing accumulation through purgation, cleaning away heat and purging pathogenic fire, cooling blood to remove internal heat, relieving internal heat or fever to heal sores, purging fire to remove toxin, removing stasis to relieve pain, promoting eruption to eliminate ecchymosis, clearing away heat to relieve pain and enlightening and inducing resuscitation. A pure traditional Chinese medicine preparation is adopted, and the external use traditional Chinese medicine composition has the advantages of being capable of directly arriving at focuses of infection in the using process, high in effect taking, free of toxic and side effects, short in treatment period and low in treatment cost.
Description
Technical field
The invention belongs to medical art, be specifically related to a kind of Chinese medicine composition, particularly relate to a kind of external medicine composition for the treatment of herpes zoster and preparation method thereof.
Background technology
Herpes zoster is the acute inflammation dermatoses caused by varicella zoster virus, and the traditional Chinese medical science is called " skirt-roof HUOLONG ", " herpes zoster ".Among the peoplely be commonly called as " herpes zoster ", " herpes zoster ".Generally first have varicella zoster virus to infect, cause chickenpox or inapparent infection, this virus is hidden lastingly in the neuron of spinal cord posterior root ganglion, under the impact of various risk factor, makes it movable again and herpes zoster occurs.Clinically with along the distribution of one-sided peripheral nerve, integrate bunch property foxtail millet grain to the large vesicle of Semen phaseoli radiati as feature, often with obvious neuralgia.Long-term practice through inventor draws, Chinese medicine is controlled herpes zoster and had better effect, obtains good effect.Primary disease is apt to occur in adult, and season in spring and autumn is common.Sickness rate increases with the age and rises in remarkable.Premorbid a few days skin is often felt allergy and neuralgia, can with General Symptomies such as heating, general malaise, inappetence; First there is flushing speckle in skin lesion initial stage affected part, then there is cluster and the chestnut grain do not merged to the large pimple of Semen Glycines, become rapidly vesicle, bleb liquid is transparent, and bleb wall is tight bright shinny, periphery blush.Dermexanthesis successively, Chang Yici is zonal distribution along nerve; After a few days, vesicle dries up, forms a scab, and leaves over temporary transient pigmentation spots more afterwards, and the method for the treatment of herpes zoster exists following difficult point at present: one is that treatment cycle is long, and patient suffering is large.Two is condition, leaves over serious neurological pain.Three is that existing Therapeutic Method is oral adopts the therapies such as antiinflammatory, antiviral, infection, analgesia more, but unsatisfactory curative effect, side effect is comparatively large, and medical expense is higher, and even some patient loses intractable long neuralgia, unfavorable to patient health.And Chinese traditional treatment primary disease, with righting benefiting QI and nourishing blood, heat-clearing and toxic substances removing, promoting blood circulation to disperse blood clots and relieves pain for the rule for the treatment of, clinical normal according to the determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs of different disease type.Therefore, develop a kind of pure Chinese medicine for external application, have no side effect, the external medicine composition of effective ingredient can go directly focus instant effect, treatment cycle is short, medical expense is low treatment herpes zoster and preparation method thereof tool is of great significance.
Summary of the invention
The object of the invention is to overcome the deficiencies in the prior art and a kind of formula advantages of simple, pure Chinese medicine for external application be provided, have no side effect, the external medicine composition of effective ingredient can go directly focus instant effect, treatment cycle is short, medical expense is low treatment herpes zoster and preparation method thereof.
Technical solution of the present invention is: a kind of external medicine composition for the treatment of herpes zoster, every agent medicine is prepared from by following raw materials according, and the weight of each crude drug is: Radix Et Rhizoma Rhei 28-32g, Cortex Phellodendri 29-31g, Radix Scutellariae 27-33g, Rhizoma Polygoni Cuspidati 28-32g, Radix Arnebiae (Radix Lithospermi) 27-34g, Radix Sanguisorbae 25-35g, Pericarpium Papaveris 28-30g, Borneolum Syntheticum 4-8g.
Described a kind of external medicine composition for the treatment of herpes zoster, every agent medicine is prepared from by following raw materials according, and the weight of each crude drug is: Radix Et Rhizoma Rhei 30g, Cortex Phellodendri 30g, Radix Scutellariae 30g, Rhizoma Polygoni Cuspidati 30g, Radix Arnebiae (Radix Lithospermi) 30g, Radix Sanguisorbae 30g, Pericarpium Papaveris 30g, Borneolum Syntheticum 6g.
The preparation method of the external medicine composition of described treatment herpes zoster, comprises the steps:
Step 1: get the raw materials ready: get potion crude drug, the weight of each crude drug is: Radix Et Rhizoma Rhei 28-32g, Cortex Phellodendri 29-31g, Radix Scutellariae 27-33g, Rhizoma Polygoni Cuspidati 28-32g, Radix Arnebiae (Radix Lithospermi) 27-34g, Radix Sanguisorbae 25-35g, Pericarpium Papaveris 28-30g, Borneolum Syntheticum 4-8g;
Step 2: concoct: the raw material prepared of first step 1 being got the raw materials ready puts into crock, the Oleum sesami first adding 700g in crock seals immersion 3 days; Then adopt slow fire to decoct, fried crude drug is to withered and yellow; Last elimination medicinal residues, obtain medicine oil.
Usage: oily obliterating affected part of getting it filled, every day 4-5 time.
Gather theory of Chinese medical science below and beneficial effect of the present invention be described:
The present invention treats primary disease, with righting benefiting QI and nourishing blood, heat-clearing and toxic substances removing, promoting blood circulation to disperse blood clots and relieves pain for the rule for the treatment of, uses: Radix Et Rhizoma Rhei heat and toxic materials clearing away, clearing away heat-fire, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation, dampness removing jaundice eliminating; Cortex Phellodendri heat clearing and damp drying, pathogenic fire purging removes steams, detoxification sore treatment; Radix Scutellariae heat clearing and damp drying, eliminating fire and detoxication, hemostasis; Rhizoma Polygoni Cuspidati dampness removing jaundice eliminating, heat-clearing and toxic substances removing, eliminating stasis to stop pain, relieving cough and resolving phlegm; Radix Arnebiae (Radix Lithospermi) clearing away heat and cooling blood, promoting blood circulation and detoxication, rash speckle removing; Blood on Radix Sanguisorbae removing heat from blood, heat-clearing and toxic substances removing; Pericarpium Papaveris is astringed the lung, astringing intestine to stop diarrhea, pain relieving; Borneolum Syntheticum is had one's ideas straightened out refreshment, clearing away heat to alleviate pain; Above-mentioned all medicine compatibilities get up, and complementation is use mutually, has heat and toxic materials clearing away, clearing away heat-fire, removing pathogenic heat from blood and toxic substance from the body, detoxification sore treatment, eliminating fire and detoxication, eliminating stasis to stop pain, rash speckle removing, clearing away heat to alleviate pain, the effect of refreshment of having one's ideas straightened out; The present invention adopts pure Chinese medicinal preparation, focus of going directly when having use instant effect, has no side effect, treatment cycle is short, advantage that medical expense is low.
The pharmacological property of each crude drug of the present invention is analyzed as follows:
1) Radix Et Rhizoma Rhei: be belong to the one in rhubarb medicinal material processed product, polygonum rheum palmatum, the dry root and rhizome of Rheum tanguticum or Rheum officinale.
Nature and flavor with return through: bitter, cold.Return spleen, stomach, large intestine, liver, pericardium channel.
Function cures mainly: heat and toxic materials clearing away, clearing away heat-fire, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation, dampness removing jaundice eliminating.To stagnate constipation for excess-heat, heat in blood tells nosebleed, conjunctival congestion pharyngeal swelling, carbuncle furuncle, abdominalgia with intestinal abscess, blood stasis amenorrhea, postpartum stagnation, traumatic injury, hygropyretic dysentery, jaundice dark coloured urine, stranguria, edema; Externally treating burns and scalds.Radix et Rhizoma Rhei (stir-fried with wine) is apt to clear part of the body cavity above the diaphragm housing the heart and lungs noxious heat in the blood system.For conjunctival congestion pharyngeal swelling, gingivitis.Radix Et Rhizoma Rhei rushes down exerts oneself to delay, eliminating fire and detoxication.For pathogenic fire,toxin and furuncles.Charred Radix Et Rhizoma Rhei cooling blood and removing stasis stops blooding.Stasis of blood hemorrhage is had for heat in blood.
2) Cortex Phellodendri: be the dry bark of rutaceae wampee.
Nature and flavor with return through: bitter, cold.Return kidney, urinary bladder channel.
Function cures mainly: heat clearing and damp drying, and pathogenic fire purging removes steams, detoxification sore treatment.For damp-heat dysentery, jaundice dark coloured urine, leukorrhagia pudendal pruritus, the puckery pain of pyretic stranguria, beriberi flaccidity of feet with lamenness, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema eczema.Stir-baked CORTEX PHELLODENDRI with salt solution nourishing YIN to lower pathogenic fire.For hyperactivity of fire caused by deficiency of YIN, night sweat hectic fever due to YIN-deficiency.
3) Radix Scutellariae: another name Radix Scutellariae, tsuchikane tea root are Labiatae Scutellaria herbaceos perennials.
Nature and flavor with return through: bitter, cold.Return lung, gallbladder, spleen, large intestine, small intestine meridian.
Function cures mainly: heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive.For hygropyrexia, heat-damp in summer, vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, high hot excessive thirst, heat in blood tells nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.
4) Rhizoma Polygoni Cuspidati: be dry rhizome and the root of polygonaceae plant Rhizoma Polygoni Cuspidati.
Nature and flavor with return through: micro-hardship, is slightly cold.Return liver, gallbladder, lung meridian.
Function cures mainly: dampness removing jaundice eliminating, heat-clearing and toxic substances removing, eliminating stasis to stop pain, relieving cough and resolving phlegm.For jaundice due to damp-heat, stranguria with turbid discharge, leukorrhagia, rheumatic arthralgia, carbuncle sore tumefacting virus, burn due to hot liquid or fire, amenorrhea ， mass in the abdomen, traumatic injury, cough due to lung-heat.
5) Radix Arnebiae (Radix Lithospermi): be the dry root of comfrey lithospermum euchromum Royle, Radix Arnebiae (Radix Lithospermi) or arnebia guttata Bunge.Spring, Qiu Erji excavate, removing silt, dry.
Nature and flavor with return through: sweet, salty, cold.GUIXIN, Liver Channel.
Function cures mainly: clearing away heat and cooling blood, promoting blood circulation and detoxication, rash speckle removing.Contain for heat in blood poison, macule purple is black, measles without adequate eruption, skin infection, eczema, burn due to hot liquid or fire.
6) Radix Sanguisorbae: another name Matteuccia struthiopteri, beautiful letter, Fructus Choerospondiatis is the dry root of rosaceous plant Radix Sanguisorbae or the Radix Sanguisorbae that comes into leaves.The latter practises title " continuous Radix Sanguisorbae ".Spring by during germination or autumn plant withered after excavate, removing fibrous root, cleaning, drying, or take advantage of fresh slices, dry.
Nature and flavor with return through: bitter, acid, puckery, be slightly cold.Enter liver, large intestine channel.
Function cures mainly: blood on removing heat from blood, heat-clearing and toxic substances removing.Control haematemesis, epistaxis, dysentery, metrorrhagia, hemorrhoidal hamorrhage, anal fistula, carbuncle, eczema, incised wound, burn.
7) Pericarpium Papaveris: be the drying and ripening shell of Papaveraceae poppy Semen Papaveris.Autumn is taken extracting the mature fruit after juice, breaks, removing seed and branch stalk, dry.
Nature and flavor with return through: sour, puckery, flat; Poisonous.Return lung, large intestine, kidney channel.
Function cures mainly: astringe the lung, astringing intestine to stop diarrhea, pain relieving.For chronic cough, chronic diarrhea, proctoptosis, epigastric pain.
8) Borneolum Syntheticum: another name borneolum syntheticum, borneol, Ai Fen, sheeting.Divide BORNEOLUM SYNTHETICUM and Blumeae preparatum Tabellae two class.BORNEOLUM SYNTHETICUM is the Borneolum Syntheticum that raw material synthesizes through chemical method with Oleum Terebinthinae, Camphora etc.; Blumeae preparatum Tabellae is the crystallization of fresh leaf through steam distillation, cooling gained of Compositae Herba Blumeae Balsamiferae platymiscium Balsamiferou Blumea Herb, also known as " Chinese mugwort powder " or " sheeting ".
Nature and flavor with return through: pungent, bitter, cool.GUIXIN, spleen, lung meridian.
Function cures mainly: refreshment of having one's ideas straightened out, clearing away heat to alleviate pain.For calentura coma, convulsions, apoplexy syncope due to accumulation of phlegm, stagnation of QI sudden syncope, attacked by pestiferous factors is gone into a coma, and obstruction of qi in the chest and cardialgia, conjunctival congestion, aphtha, laryngopharynx swelling and pain, auditory meatus is suppurated.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
Inventor receives the out-patient of the routine herpes zoster for the treatment of 100 altogether between year May in July, 2014 to 2015, wherein male 60 example, women 40 example, age 20-40 year.Above-mentioned treatment patient is divided at random: treatment A group 35 example, treatment B group 35 example, matched group 30 example.The data such as three groups of sexes, age, state of an illness, all without significant difference, have comparability.
Therapeutic Method:
The common nitrofural Calamine Lotion of matched group external, smears affected part 4-5 time on the 1st.7 days courses for the treatment of.
The present invention is oily according to the medicine that specific embodiment 1 is obtained for the external for the treatment of A group, obliterating affected part, every day 4-5 time.6 days courses for the treatment of.
The present invention is oily according to the medicine that specific embodiment 2 is obtained for the external for the treatment of B group, obliterating affected part, every day 4-5 time.6 days courses for the treatment of.
Observation item:
Clinical symptoms: the General Symptomies such as heating, general malaise, inappetence; First there is flushing speckle in skin lesion initial stage affected part, then there is cluster and the chestnut grain do not merged to the large pimple of Semen Glycines, become rapidly vesicle, bleb liquid is transparent, and bleb wall is tight bright shinny, periphery blush.
Lab testing: hemogram, neutrophilic granulocyte.
Criterion of therapeutical effect and therapeutic outcome
Criterion of therapeutical effect
Recovery from illness: clinical symptoms all disappears, and lab testing is normal.Take a turn for the better: clinical symptom relief, lab testing improvement or normal.Invalid: clinical symptoms is without being clearly better or increasing the weight of.
Therapeutic outcome sees the following form:
| Group | Sum | Recovery from illness | Take a turn for the better | Invalid | Bad should | Total effective rate (%) |
| Treatment A group | 35 | 30 | 4 | 1 | 0 | 97.1 |
| Treatment B group | 35 | 32 | 3 | 0 | 0 | 100 |
| Matched group | 30 | 15 | 7 | 8 | 0 | 73.3 |
Visible, the medicine that the present invention's two kinds of preferred implementations obtain all can treat herpes zoster safely and effectively.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated.
Embodiment 1
Take Radix Et Rhizoma Rhei 28g, Cortex Phellodendri 29g, Radix Scutellariae 27g, Rhizoma Polygoni Cuspidati 28g, Radix Arnebiae (Radix Lithospermi) 27g, Radix Sanguisorbae 25g, Pericarpium Papaveris 28g, Borneolum Syntheticum 4g; Put into crock, the Oleum sesami first adding 700g in crock seals immersion 3 days; Then adopt slow fire to decoct, fried crude drug is to withered and yellow; Last elimination medicinal residues, obtain medicine oil.
Usage: oily obliterating affected part of getting it filled, every day 4-5 time.
Embodiment 2
Take Radix Et Rhizoma Rhei 30g, Cortex Phellodendri 30g, Radix Scutellariae 30g, Rhizoma Polygoni Cuspidati 30g, Radix Arnebiae (Radix Lithospermi) 30g, Radix Sanguisorbae 30g, Pericarpium Papaveris 30g, Borneolum Syntheticum 6g; Put into crock, the Oleum sesami first adding 700g in crock seals immersion 3 days; Then adopt slow fire to decoct, fried crude drug is to withered and yellow; Last elimination medicinal residues, obtain medicine oil.
Usage: oily obliterating affected part of getting it filled, every day 4-5 time.
Embodiment 3
Take Radix Et Rhizoma Rhei 32g, Cortex Phellodendri 31g, Radix Scutellariae 33g, Rhizoma Polygoni Cuspidati 32g, Radix Arnebiae (Radix Lithospermi) 34g, Radix Sanguisorbae 35g, Pericarpium Papaveris 30g, Borneolum Syntheticum 8g; Put into crock, the Oleum sesami first adding 700g in crock seals immersion 3 days; Then adopt slow fire to decoct, fried crude drug is to withered and yellow; Last elimination medicinal residues, obtain medicine oil.
Usage: oily obliterating affected part of getting it filled, every day 4-5 time.
Claims (3)
1. treat external medicine composition and the preparation method of herpes zoster for one kind, it is characterized in that: every agent medicine is prepared from by following raw materials according, and the weight of each crude drug is: Radix Et Rhizoma Rhei 28-32g, Cortex Phellodendri 29-31g, Radix Scutellariae 27-33g, Rhizoma Polygoni Cuspidati 28-32g, Radix Arnebiae (Radix Lithospermi) 27-34g, Radix Sanguisorbae 25-35g, Pericarpium Papaveris 28-30g, Borneolum Syntheticum 4-8g.
2. a kind of external medicine composition and preparation method for the treatment of herpes zoster as claimed in claim 1, it is characterized in that: every agent medicine is prepared from by following raw materials according, and the weight of each crude drug is: Radix Et Rhizoma Rhei 30g, Cortex Phellodendri 30g, Radix Scutellariae 30g, Rhizoma Polygoni Cuspidati 30g, Radix Arnebiae (Radix Lithospermi) 30g, Radix Sanguisorbae 30g, Pericarpium Papaveris 30g, Borneolum Syntheticum 6g.
3. the external medicine composition for the treatment of herpes zoster as described in as arbitrary in claim 1-2 and a preparation method for preparation method, is characterized in that: described preparation method comprises the steps:
Step 1: get the raw materials ready: get potion crude drug, the weight of each crude drug is: Radix Et Rhizoma Rhei 28-32g, Cortex Phellodendri 29-31g, Radix Scutellariae 27-33g, Rhizoma Polygoni Cuspidati 28-32g, Radix Arnebiae (Radix Lithospermi) 27-34g, Radix Sanguisorbae 25-35g, Pericarpium Papaveris 28-30g, Borneolum Syntheticum 4-8g;
Step 2: concoct: the raw material prepared of first step 1 being got the raw materials ready puts into crock, the Oleum sesami first adding 700g in crock seals immersion 3 days; Then adopt slow fire to decoct, fried crude drug is to withered and yellow; Last elimination medicinal residues, obtain medicine oil.
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Cited By (1)
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| CN106377713A (en) * | 2016-11-18 | 2017-02-08 | 威海市经济技术开发区医院 | Traditional Chinese medicinal compound preparation for treating herpes zoster |
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