CN104491683A - Traditional Chinese medicine composition for treating verruca plana and preparation method of traditional Chinese medicine composition - Google Patents

Traditional Chinese medicine composition for treating verruca plana and preparation method of traditional Chinese medicine composition Download PDF

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CN104491683A
CN104491683A CN201410703962.3A CN201410703962A CN104491683A CN 104491683 A CN104491683 A CN 104491683A CN 201410703962 A CN201410703962 A CN 201410703962A CN 104491683 A CN104491683 A CN 104491683A
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chinese medicine
medicine composition
traditional chinese
verruca plana
tablet
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顾蔷怡
高春娟
冷盛君
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    • A61K36/18—Magnoliophyta (angiosperms)
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Abstract

The invention discloses a traditional Chinese medicine composition for treating verruca plana and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from purslane, radix isatidis, seeds of job's tears, wild chrysanthemum flower, fructus forsythia, honeysuckle, dandelion, raw oyster shell, rhizoma sparganic, curcuma zedoary, scutellaria baicalensis, tuber fleeceflower stem and liquorice in combination at a certain ratio. According to the traditional Chinese medicine composition, the seeds of job's tears are adopted as a monarch drug, and have the efficacies of inducing diuresis to alleviate edema, tonifying the spleen, removing dampness, relaxing muscles and tendons, removing pyralysis, clearing away heat, eliminating pus, smoothing the skin, reducing wrinkles and removing pigment spots; the purslane, the raw oyster shell and the radix isatidis are taken as minister drugs; and the honeysuckle, the fructus forsythia, the wild chrysanthemum flower, the dandelion and the tuber fleeceflower stem are taken as adjuvant drugs, and therefore, the traditional Chinese medicine composition has an accurate curative effect on treatment of the verruca plana.

Description

A kind of Chinese medicine composition for the treatment of verruca plana and preparation method thereof
Technical field
The present invention relates to a kind of is Chinese medicine composition of crude drug and preparation method thereof by Chinese herbal medicine, relates to a kind of Chinese medicine composition for the treatment of verruca plana and preparation method thereof specifically.
Background technology
Verruca plana is infected by human papillomavirus (HPV) and causes, and is apt to occur in teen-age disease of viral infection.Clinical manifestation is color of the leather or peach flat pimple, and without obvious subjective symptoms, the course of disease is chronic.By direct or indirect contagion.Can onset suddenly, skin lesion is mainly in face, the back of the hand, arm, show as the flat pimple differed in size, slight protuberance, smooth surface, rounded, oval or polygon, boundary is clear, can dense distribution or owing to scratch and in the linear alignment local, general no conscious sympton, the conscious slight pruritus of some patients.The course of disease is chronic process, for many years sustainable.Doctor trained in Western medicine mainly adopts following therapeutic scheme: topical medication: external adopts the treatments such as Retinoic acid ointment, imiquimod ointment; Physical therapy: comprise freezing and laser therapy; Oral medicine: the oral isotretinoin capsule for treating of severe patient.Existing drug treatment suppresses viral, antitoxin side effect is less; Physiotherapy easily causes recurrence; Some patients leaves the sequela such as cicatrix, pigmentation after treatment, and therapeutic effect is not good enough.
Summary of the invention
The present invention, from clinical treatment medication demand and the dialectical principle of traditional Chinese medical science prescription, proposes a kind of Chinese medicine composition for the treatment of verruca plana and preparation method thereof.It is the medicament be prepared from by the crude drug of following parts by weight proportioning: Herba Portulacae 12-18g, Radix Isatidis 12-18g, seed of Jobs tears 27-33g, Flos Chrysanthemi Indici 7-13g, Fructus Forsythiae 7-13g, Flos Lonicerae 7-13g, Herba Taraxaci 7-13g, Concha Ostreae 12-18g, Rhizoma Sparganii 7-13g, Rhizoma Curcumae 7-13g, Radix Scutellariae 7-13g, Caulis Polygoni Multiflori 7-13g, Radix Glycyrrhizae 3-9g.Optimum ratio is: Herba Portulacae 15g, Radix Isatidis 15g, seed of Jobs tears 30g, Flos Chrysanthemi Indici 10g, Fructus Forsythiae 10g, Flos Lonicerae 10g, Herba Taraxaci 10g, Concha Ostreae 15g, Rhizoma Sparganii 10g, Rhizoma Curcumae 10g, Radix Scutellariae 10g, Caulis Polygoni Multiflori 10g, Radix Glycyrrhizae 6g.Described medicament is capsule, tablet or pill.
The preparation method step of described capsule, tablet, pill is as follows:
(1) in the side of getting, Herba Portulacae, Radix Isatidis, seed of Jobs tears, Flos Chrysanthemi Indici, Fructus Forsythiae, Flos Lonicerae, Herba Taraxaci, Concha Ostreae, Rhizoma Sparganii, Rhizoma Curcumae, Radix Scutellariae, Caulis Polygoni Multiflori, Radix Glycyrrhizae pulverize screen analysis;
(2) decocted with water 2-3 time by the mixture of sieve series in step (1), collecting decoction, filtration, worry liquid is condensed into 70-80 when spending, capsule, pill relative density are the thick paste of 1.0-1.6, and tablet relative density is the thick paste of 1.0-1.4;
(3) when making capsule, pill:
By thick paste separation and purification, drying, make dry granule; By dry granule mix homogeneously, in filled capsules, namely make capsule; Dry granule spray is added refined honey, mix homogeneously, makes piller and namely make pill;
When making tablet:
2-4 part starch is mixed homogeneously with the thick paste in step (2), makes granule, drying, make dry granule, dry granule is pressed into tablet, sugar coating, namely makes tablet.
Mixture described in step (2), the preferred number of times decocted with water is 2 times, and first time is 60-80 minute, and second time is 40-60 minute.
crude drug pharmacology of the present invention is as follows:
Herba Portulacae: have clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling, antiinflammatory, quench the thirst, diuresis, modern study, Herba Portulacae is also containing abundant SL3 fatty acid and vitamin A sample material.SL3 fatty acid forms cell membrane, especially brain cell membrane and the necessary material of eye cell membrane; Vitamin A sample substance maintains epithelial tissue as the normal function of skin, also participates in many oxidizing processs in body;
Radix Isatidis: the effect with heat-clearing and toxic substances removing, blood cooling and ecchymoses removing, relieving sore throat and pain; Inhibitory action is had to various bacteria. infusion has inhibitory action in various degree to bacillus subtilis, staphylococcus aureus, sarcine, escherichia coli, Bacillus typhi, Salmonella paratyphi, dysentery (will congratulate, Fu Shi) bacillus, bacillus enteritidis etc.;
Seed of Jobs tears: seed of Jobs tears and SEMEN COICIS; SEMEN COICIS belongs to grass.Have two kinds, one is Semen Coicis, and shell is hard and thick, is commonly called as the Fructus Sapindi Mukouossi.One is Semen Coicis, and shell is thinner and glutinous, can be edible.Both this, performance is roughly close, and is good with the latter.Root is also done medicinal.There is inducing diuresis to remove edema, the effect such as spleen invigorating is dried, arthralgia relieving by relaxing muscles and tendons, clearing away heat and discharging pus, for skin, have and make skin smooth, reduce wrinkle, eliminate effect of pigment spot;
Flos Chrysanthemi Indici: can treat furuncle carbuncle, laryngopharynx swelling and pain, wind-fire acute conjunctivitis, the disease such as dizzy of having a headache, has that sterilization goes to swell, furuncle, carbuncle, erysipelas, eczema, dermatitis effect;
Fructus Forsythiae: there is heat clearing away, removing toxic substances, eliminating stagnation, logical small intestinal, evacuation of pus, controls furuncle, pain relieving, and loose all menses stagnation of QI gather, detumescence effect;
Flos Lonicerae: can dispelling wind-heat, also kind removing summer-heat blood poison, for various febrile disease, as fever of the body, dermexanthesis, send out the diseases such as speckle, pyretic toxicity carbuncle sore, laryngopharynx swelling and pain, Be very effective;
Herba Taraxaci: have the effects such as diuresis, cathartic, jaundice eliminating subcutaneous ulcer, function of gallbladder promoting, control pyretic toxicity, carbuncle, skin infection, abscess of internal organ, conjunctival congestion and swelling pain, damp and hot, the puckery pain of jaundice, dribbling urination, furuncle swelling toxin, acute mastitis, scrofula, toothache, conjunctival congestion, pharyngalgia, lung abscess, acute appendicitis, jaundice due to damp-heat, the puckery pain of pyretic stranguria, controls acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infection etc.;
Concha Ostreae: suppressing the hyperactive liver and subsiding YANG, tranquillization with heavy prescription, hard masses softening and resolving, convergence are astringent or styptic treatment for spontaneous sweating, has YIN nourishing, nourishes blood, tonifying five ZANG-organs, invigorates blood circulation, fills the effects such as flesh;
Rhizoma Sparganii: swollen pain, traumatic injury, skin ulcer swell hard down to control lump in the abdomen, coagulation of QI-blood, trusted subordinate's pain, the side of body;
Rhizoma Curcumae: removing blood stasis circulation of qi promoting, removing food stagnancy pain relieving, lump in the abdomen lump;
Radix Scutellariae: have heat clearing and damp drying, eliminating fire and detoxication, hemostasis, cures mainly the disease such as epidemic febrile disease, carbuncle furuncle;
Caulis Polygoni Multiflori: cure mainly empty general pain of losing blood, carbuncle, scrofula, wind skin ulcer scabies;
Radix Glycyrrhizae: for ulcer sores, is equal to the merit with there being heat-clearing and toxic substances removing with golden Flos Lonicerae, Fructus Forsythiae;
The present invention take seed of Jobs tears as monarch drug, and inducing diuresis to remove edema, spleen invigorating dry, arthralgia relieving by relaxing muscles and tendons, clearing away heat and discharging pus, make skin smooth, reduces wrinkle, eliminates pigment spot.
With Herba Portulacae, Concha Ostreae, Radix Isatidis for ministerial drug, clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling, antiinflammatory, YIN nourishing, nourishes blood, tonifying five ZANG-organs, invigorates blood circulation, fills flesh, heat-clearing and toxic substances removing, blood cooling and ecchymoses removing, anti-bacteria.Assistant is with Flos Lonicerae, Fructus Forsythiae, Flos Chrysanthemi Indici, Herba Taraxaci, Caulis Polygoni Multiflori, and for ulcer sores, dermexanthesis, send out speckle, pyretic toxicity carbuncle sore, sterilization goes to swell, furuncle, carbuncle, erysipelas, eczema, dermatitis, detumescence, carbuncle, scrofula, wind skin ulcer scabies; Make with Radix Glycyrrhizae, Radix Scutellariae, Rhizoma Curcumae, Rhizoma Sparganii, heat-clearing and toxic substances removing, heat clearing and damp drying, eliminating fire and detoxication, carbuncle furuncle of dispelling, removing blood stasis circulation of qi promoting, removing food stagnancy pain relieving, lump in the abdomen lump, skin ulcer swells hard.Chinese medicine composition of the present invention holds the marrow of the traditional Chinese medical science, rigorous prescription, and all medicine monarch share, and mends broken combination, brings out the best in each other, meet the principle of traditional Chinese medical science medicine law and determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs.
Chinese medicine composition for a better understanding of the present invention, does clinical trial as follows:
1, select case: subjects is 123 routine verruca plana patients, wherein male 63 example, women 60 example, the age 21-58 year between, most of patients adopted Western medicine, physiotherapy, but therapeutic effect is not good.
2, diagnostic criteria:
In face, the back of the hand, arm, show as the flat pimple differed in size, slightly swell, smooth surface, rounded, oval or polygon, boundary is clear, can dense distribution or owing to scratch and in the linear alignment local, general no conscious sympton, the conscious slight pruritus of some patients.
3, therapeutic scheme:
Every day 1 dose, decocting, takes orally at twice, within 5 days, is a course for the treatment of, continuous four courses for the treatment of.
4, the standard of curative effect evaluation:
Verruca plana variable color peeling, comes off then, affected part preventing from scar after all coming off.
5, therapeutic effect:
6, statistical result
Clinically to 123 routine verruca plana patients between department of dermatologry 2010-2013, wherein male 63 example, women 60 example, age, between 21-58 year, uses this medicine therapist to add up, statistical result showed, this Chinese medicine composition achieves noticeable achievement to treating flat wart effect aspect, and cure rate is 97.56%.
The Chinese medicine composition for the treatment of verruca plana of the present invention, verruca plana size <=1mm2's, one-two course for the treatment of can cure, verruca plana size 1-2 mm2's, three courses for the treatment of can cure, verruca plana size >=2 mm2, and four courses for the treatment of can cure or alleviate.Chinese medicine composition of the present invention has good effect to treatment verruca plana.
Western medicine checks: after treatment, and patient's pathologic finding verruca plana place epidermal thickness is roughly normal, basal layer hyperpigmentation, the visible melanophage of high dermis.
Acute toxicity test: larger dose and take to the growth of rat without remarkable toxicity compared with long-term therapy, have no overt toxicity damage to the chip form inspection such as brain, the heart, liver, kidney of rat and change, test display, this drug toxicity is very little.
Detailed description of the invention
embodiment 1:a kind of Chinese medicine composition for the treatment of verruca plana and preparation method thereof.It is the medicament be prepared from by the crude drug of following parts by weight proportioning: Herba Portulacae 12-18g, Radix Isatidis 12-18g, seed of Jobs tears 27-33g, Flos Chrysanthemi Indici 7-13g, Fructus Forsythiae 7-13g, Flos Lonicerae 7-13g, Herba Taraxaci 7-13g, Concha Ostreae 12-18g, Rhizoma Sparganii 7-13g, Rhizoma Curcumae 7-13g, Radix Scutellariae 7-13g, Caulis Polygoni Multiflori 7-13g, Radix Glycyrrhizae 3-9g.Described medicament is capsule, tablet or pill.
According to following portions by weight proportioning weighting raw materials:
Herba Portulacae 12-18g, Radix Isatidis 12-18g, seed of Jobs tears 27-33g, Flos Chrysanthemi Indici 7-13g, Fructus Forsythiae 7-13g, Flos Lonicerae 7-13g, Herba Taraxaci 7-13g, Concha Ostreae 12-18g, Rhizoma Sparganii 7-13g, Rhizoma Curcumae 7-13g, Radix Scutellariae 7-13g, Caulis Polygoni Multiflori 7-13g, Radix Glycyrrhizae 3-9g.
The preparation method step of described capsule, tablet, pill is as follows:
(1) in the side of getting, Herba Portulacae, Radix Isatidis, seed of Jobs tears, Flos Chrysanthemi Indici, Fructus Forsythiae, Flos Lonicerae, Herba Taraxaci, Concha Ostreae, Rhizoma Sparganii, Rhizoma Curcumae, Radix Scutellariae, Caulis Polygoni Multiflori, Radix Glycyrrhizae pulverize screen analysis;
(2) decocted with water 2-3 time by the mixture of sieve series in step (1), collecting decoction, filtration, worry liquid is condensed into 70-80 when spending, capsule, pill relative density are the thick paste of 1.0-1.6, and tablet relative density is the thick paste of 1.0-1.4;
(3) when making capsule, pill:
By thick paste separation and purification, drying, make dry granule; By dry granule mix homogeneously, in filled capsules, namely make capsule; Dry granule spray is added refined honey, mix homogeneously, makes piller and namely make pill;
When making tablet:
2-4 part starch is mixed homogeneously with the thick paste in step (2), makes granule, drying, make dry granule, dry granule is pressed into tablet, sugar coating, namely makes tablet.
Mixture described in step (2), the preferred number of times decocted with water is 2 times, and first time is 60-80 minute, and second time is 40-60 minute.
embodiment 2:a kind of Chinese medicine composition for the treatment of verruca plana and preparation method thereof.It is the medicament be prepared from by the crude drug of following parts by weight proportioning: Herba Portulacae 15g, Radix Isatidis 15g, seed of Jobs tears 30g, Flos Chrysanthemi Indici 10g, Fructus Forsythiae 10g, Flos Lonicerae 10g, Herba Taraxaci 10g, Concha Ostreae 15g, Rhizoma Sparganii 10g, Rhizoma Curcumae 10g, Radix Scutellariae 10g, Caulis Polygoni Multiflori 10g, Radix Glycyrrhizae 6g.Described medicament is capsule, tablet or pill.
According to following portions by weight proportioning weighting raw materials:
Herba Portulacae 15g, Radix Isatidis 15g, seed of Jobs tears 30g, Flos Chrysanthemi Indici 10g, Fructus Forsythiae 10g, Flos Lonicerae 10g, Herba Taraxaci 10g, Concha Ostreae 15g, Rhizoma Sparganii 10g, Rhizoma Curcumae 10g, Radix Scutellariae 10g, Caulis Polygoni Multiflori 10g, Radix Glycyrrhizae 6g.
The preparation method step of described capsule, tablet, pill is as follows:
(1) in the side of getting, Herba Portulacae, Radix Isatidis, seed of Jobs tears, Flos Chrysanthemi Indici, Fructus Forsythiae, Flos Lonicerae, Herba Taraxaci, Concha Ostreae, Rhizoma Sparganii, Rhizoma Curcumae, Radix Scutellariae, Caulis Polygoni Multiflori, Radix Glycyrrhizae pulverize screen analysis;
(2) decocted with water 2-3 time by the mixture of sieve series in step (1), collecting decoction, filtration, worry liquid is condensed into 70-80 when spending, capsule, pill relative density are the thick paste of 1.0-1.6, and tablet relative density is the thick paste of 1.0-1.4;
(3) when making capsule, pill:
By thick paste separation and purification, drying, make dry granule; By dry granule mix homogeneously, in filled capsules, namely make capsule; Dry granule spray is added refined honey, mix homogeneously, makes piller and namely make pill;
When making tablet:
2-4 part starch is mixed homogeneously with the thick paste in step (2), makes granule, drying, make dry granule, dry granule is pressed into tablet, sugar coating, namely makes tablet.
Mixture described in step (2), the preferred number of times decocted with water is 2 times, and first time is 60-80 minute, and second time is 40-60 minute.
Embodiment 3: medicine of the present invention can also be decoction, oral liquid, granule etc.

Claims (5)

1. treat a Chinese medicine composition for verruca plana, it is characterized in that it is the medicament be prepared from by the crude drug of following parts by weight proportioning: Herba Portulacae 12-18g, Radix Isatidis 12-18g, seed of Jobs tears 27-33g, Flos Chrysanthemi Indici 7-13g, Fructus Forsythiae 7-13g, Flos Lonicerae 7-13g, Herba Taraxaci 7-13g, Concha Ostreae 12-18g, Rhizoma Sparganii 7-13g, Rhizoma Curcumae 7-13g, Radix Scutellariae 7-13g, Caulis Polygoni Multiflori 7-13g, Radix Glycyrrhizae 3-9g.
2. the Chinese medicine composition for the treatment of verruca plana according to claim 1, is characterized in that it is the medicament be prepared from by the crude drug of following parts by weight proportioning: Herba Portulacae 15g, Radix Isatidis 15g, seed of Jobs tears 30g, Flos Chrysanthemi Indici 10g, Fructus Forsythiae 10g, Flos Lonicerae 10g, Herba Taraxaci 10g, Concha Ostreae 15g, Rhizoma Sparganii 10g, Rhizoma Curcumae 10g, Radix Scutellariae 10g, Caulis Polygoni Multiflori 10g, Radix Glycyrrhizae 6g.
3. the Chinese medicine composition for the treatment of verruca plana according to claim 1 and 2, is characterized in that: described medicament is capsule, tablet or pill.
4. the Chinese medicine composition for the treatment of verruca plana according to claim 3, is characterized in that: the preparation method step of described capsule, tablet, pill is as follows:
(1) in the side of getting, Herba Portulacae, Radix Isatidis, seed of Jobs tears, Flos Chrysanthemi Indici, Fructus Forsythiae, Flos Lonicerae, Herba Taraxaci, Concha Ostreae, Rhizoma Sparganii, Rhizoma Curcumae, Radix Scutellariae, Caulis Polygoni Multiflori, Radix Glycyrrhizae pulverize screen analysis;
(2) decocted with water 2-3 time by the mixture of sieve series in step (1), collecting decoction, filtration, worry liquid is condensed into 70-80 when spending, capsule, pill relative density are the thick paste of 1.0-1.6, and tablet relative density is the thick paste of 1.0-1.4;
(3) when making capsule, pill:
By thick paste separation and purification, drying, make dry granule; By dry granule mix homogeneously, in filled capsules, namely make capsule; Dry granule spray is added refined honey, mix homogeneously, makes piller and namely make pill;
When making tablet:
2-4 part starch is mixed homogeneously with the thick paste in step (2), makes granule, drying, make dry granule, dry granule is pressed into tablet, sugar coating, namely makes tablet.
5. the preparation method of the Chinese medicine composition for the treatment of verruca plana according to claim 4, is characterized in that the mixture described in step (2), and the number of times decocted with water is 2 times, and first time is 60-80 minute, and second time is 40-60 minute.
CN201410703962.3A 2014-11-30 2014-11-30 Traditional Chinese medicine composition for treating verruca plana and preparation method of traditional Chinese medicine composition Pending CN104491683A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105079603A (en) * 2015-09-18 2015-11-25 江南大学 Traditional Chinese medicinal composition for treating verruca plana and preparation method of traditional Chinese medicinal composition

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012041275A (en) * 2010-08-12 2012-03-01 Yukitoshi Yanagi Skin astringent composition
CN102397511A (en) * 2011-11-12 2012-04-04 张棠 Medicament for treating flat wart
CN102836357A (en) * 2011-06-22 2012-12-26 惠振明 Traditional Chinese medicine preparations used for treating flat warts

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012041275A (en) * 2010-08-12 2012-03-01 Yukitoshi Yanagi Skin astringent composition
CN102836357A (en) * 2011-06-22 2012-12-26 惠振明 Traditional Chinese medicine preparations used for treating flat warts
CN102397511A (en) * 2011-11-12 2012-04-04 张棠 Medicament for treating flat wart

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
雷振萍: "《实用中医美容》", 31 December 1990, 广西科学技术出版社 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105079603A (en) * 2015-09-18 2015-11-25 江南大学 Traditional Chinese medicinal composition for treating verruca plana and preparation method of traditional Chinese medicinal composition
CN105079603B (en) * 2015-09-18 2018-11-06 江南大学 A kind of Chinese medicine composition and preparation method thereof for treating flat wart

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