CN105287977A - Sweet basil herb and aloe composition and preparation as well as preparation method and application of sweet basil herb and aloe composition - Google Patents

Sweet basil herb and aloe composition and preparation as well as preparation method and application of sweet basil herb and aloe composition Download PDF

Info

Publication number
CN105287977A
CN105287977A CN201510908687.3A CN201510908687A CN105287977A CN 105287977 A CN105287977 A CN 105287977A CN 201510908687 A CN201510908687 A CN 201510908687A CN 105287977 A CN105287977 A CN 105287977A
Authority
CN
China
Prior art keywords
herba ocimi
aloe
extract
pilosi
juice
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201510908687.3A
Other languages
Chinese (zh)
Other versions
CN105287977B (en
Inventor
于晓
张芳
李松涛
刘一鸣
刘建升
刁兴彬
孙希芳
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201510908687.3A priority Critical patent/CN105287977B/en
Publication of CN105287977A publication Critical patent/CN105287977A/en
Application granted granted Critical
Publication of CN105287977B publication Critical patent/CN105287977B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/886Aloeaceae (Aloe family), e.g. aloe vera
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Medical Informatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Birds (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a sweet basil herb and aloe composition and preparation as well as a preparation method and application of the of sweet basil herb and aloe composition, and belongs to the technical field of Chinese herbal medicines. The mass ratio of sweet basil herb to aloe in the composition is (1-10):(1-10), and the composition can also comprise 0.5-2 parts by weight of Sinkiang arnebia root. The sweet basil herb and aloe composition disclosed by the invention has good effects of reducing swelling, relieving itching and sterilizing to diminish inflammation, can be used for treating mosquito bites, eczemas, pimples, acnes and burns and scalds, and is simple in medicinal constitution, thereby reducing production process steps and lowering the production cost. The sweet basil herb and aloe composition has relatively good economic values.

Description

A kind of Herba Ocimi (Herba Ocimi Pilosi), aloe composition, preparation and its preparation method and application
Technical field
The present invention relates to field of Chinese herbal medicine technology, be specifically related to a kind of Herba Ocimi (Herba Ocimi Pilosi), aloe composition, preparation and its preparation method and application.
Background technology
Herba Ocimi (Herba Ocimi Pilosi) is medicine-food two-purpose fragrant plant, have powerful, stimulate, fragrance abnormal smells from the patient.Herba Ocimi (Herba Ocimi Pilosi) is containing volatile oil 0.02 ~ 0.04%, main component is ocimene, australene, 1,8-cineole, linalool, Geraniol, limonene, 3-carene, estragole, eugenol, methyleugenol, methoxybenzene, methyl cinnamate, blatter alcohol, 3-octanone and furfural etc.Herba Ocimi (Herba Ocimi Pilosi) can be used for dispelling wind circulation of qi promoting, and removing dampness helps digestion, the function of invigorating blood circulation, detoxifying, for headache due to invasion of exogenous pathogens, the flatulence due to improper diet stagnation of QI, gastralgia, have loose bowels, menoxenia, traumatic injury, snake bite and insect sting, skin eczema, the disease such as urticaria sufferings treatment.
Aloe is Liliaceae perennial evergreen herbaceous plant, has bactericidal action, antiinflammatory action, moistening beautification function, effect is let out, the heart tonifying effect of invigorating blood circulation, immunity and regeneration, immunity and antitumor action under stomach invigorating, Detoxication, anti-aging effects, analgesia, sedation, anti-sunlight function.Aloe folks of china just by as beauty treatment, hair care and treatment dermatosis natural drug.
Radix Arnebiae (Radix Lithospermi) nature and flavor are sweet, salty, cold, GUIXIN, Liver Channel, and removing heat from blood, invigorates blood circulation, heat clearing away, effect of removing toxic substances, and its effective ingredient is acetylshikonin, beta-hydroxyisovalerylshiderivative, shikonin, β, β '-dimethylacrylshikonin etc.Clinically, Radix Arnebiae (Radix Lithospermi) is mainly used in treating the diseases such as warm macule, purpura, burn, eczema, erysipelas, carbuncle and ulcer.
The medicine of existing multiple repellent antipruritic, bactericidal antiphlogistic effect in the market, but medicine composition is complicated, and poor stability, complex production process, commercial production cost is high, is unfavorable for business economic benefit, thus lacks the market competitiveness.
Summary of the invention
For solving the defect that prior art exists, the present invention aims to provide a kind of Herba Ocimi (Herba Ocimi Pilosi), aloe composition, preparation and its preparation method and application, Herba Ocimi (Herba Ocimi Pilosi) of the present invention, aloe composition have good repellent antipruritic, bactericidal antiphlogistic effect, can be used for the treatments such as mosquito bite, eczema, comedo, acne and burn and scald, medicine composition is simple, thus minimizing production craft step, reduce production cost, there is good economic worth.
To achieve these goals, technical scheme of the present invention is:
The invention provides a kind of for subsiding a swelling, antipruritic, the Herba Ocimi (Herba Ocimi Pilosi) of antiinflammatory, aloe composition, described Herba Ocimi (Herba Ocimi Pilosi), Aloe mass ratio are (1-10): (1-10).
Preferably, described Herba Ocimi (Herba Ocimi Pilosi), Aloe mass ratio are (1-3): (1-2).
Preferably, described Herba Ocimi (Herba Ocimi Pilosi), Aloe mass ratio are 2:1.
Preferably, described compositions also comprises the Radix Arnebiae (Radix Lithospermi) of 0.5-2 weight portion.
Present invention also offers above-mentioned detumescence, antipruritic, the Herba Ocimi (Herba Ocimi Pilosi) of antiinflammatory, the preparation method of aloe composition, described Herba Ocimi (Herba Ocimi Pilosi) is by squeezing the juice or adopting solvent extraction to obtain Herba Ocimi extract (Herba Ocimi Pilosi extract), Herba Ocimi extract (Herba Ocimi Pilosi extract) and Aloe extract, by squeezing the juice after peeling or adopting solvent extraction to obtain Aloe extract, are mixed by described Aloe.
Above-mentioned detumescence containing Radix Arnebiae (Radix Lithospermi), antipruritic, the Herba Ocimi (Herba Ocimi Pilosi) of antiinflammatory, the preparation method of aloe composition, described Herba Ocimi (Herba Ocimi Pilosi) is by squeezing the juice or adopting solvent extraction to obtain Herba Ocimi extract (Herba Ocimi Pilosi extract), described Aloe is by squeezing the juice after peeling or adopting solvent extraction to obtain Aloe extract, described Radix Arnebiae (Radix Lithospermi) obtains Radix Arnebiae extract for adopting solvent extraction, described Radix Arnebiae extract and described Herba Ocimi extract (Herba Ocimi Pilosi extract) and Aloe extract is mixed.
Preferably, described extract all adopts volumetric concentration to be the ethanol extraction of 40-95%, further the ethanol extraction of preferred 65-95%.
Invention additionally provides above-mentioned detumescence, the Herba Ocimi (Herba Ocimi Pilosi) of antipruritic, antiinflammatory, the application of aloe composition in the external preparation for skin medicine of preparation treatment mosquito bite, eczema, comedo, acne or burn and scald, externally-applied health-care products, cosmetics for external use, dissipation product or its additive.
Described external preparation for skin medicine, externally-applied health-care products or cosmetics for external use are spray, gel, ointment, lotion, membrane or wet tissue.
" extract " of the present invention refers to that being is raw material with plant (, on the ground leaf, stem portion, Radix Arnebiae (Radix Lithospermi) is subterraneous root part for Herba Ocimi (Herba Ocimi Pilosi), Aloe), according to the needs of the purposes to the final products extracted, obtains product through physical chemistry extraction and isolation.Such as extract of the present invention can obtain its liquid part by methods such as squeezing method or ethanol extractions, and this liquid part comprises its effective ingredient, and facilitates the needs of preparation.
Beneficial effect of the present invention is:
1) the present invention is raw materials used is extracted form natural plant, without chemical raw material, gentle to human-body safety, has no side effect, can life-time service, more meets natural, healthy consumption concept;
2) the raw materials used kind of the present invention is few, and equal wide material sources, be easy to obtain, reduce commercial production Raw acquisition aspect time, Financial cost;
3) the raw materials used Herba Ocimi (Herba Ocimi Pilosi) of the present invention, Aloe have than independent better repellent antipruritic, bactericidal antiphlogistic action effect separately when sharing, namely both share as synergism, good drug efficacy, environmental protection, medicine composition is simple, decrease production craft step, reduce commercial production cost, there is good economic worth and the market competitiveness.
This product has no side effect, and technique is simple, evident in efficacy, is especially directed to infant mosquito bite effect very remarkable, wide market.
Additional aspect of the present invention and advantage will part provide in the following description, and part will become obvious from the following description, or be recognized by practice of the present invention.
Detailed description of the invention
Below in conjunction with instantiation, the present invention is described in detail.
Embodiment 1
Get fresh Herba Ocimi (Herba Ocimi Pilosi) aerial parts 10Kg, clean, put in juice extractor and squeeze the juice, filter, obtain Herba Ocimi (Herba Ocimi Pilosi) juice 1.25Kg; Get Aloe 10Kg, clean, after skin upper and lower for Folium Aloe is removed, rinse the part after peeling a little with water, put in juice extractor and squeeze the juice, obtain Aloe juice 4.82Kg; The Herba Ocimi (Herba Ocimi Pilosi) juice 1Kg and the Aloe juice 1Kg that get above-mentioned gained respectively mix, and stir, and gained mixed liquor is loaded spray bottle and namely obtains a kind of Herba Ocimi (Herba Ocimi Pilosi) of the present invention, aloe composition gel spray.
Embodiment 2
Get fresh Herba Ocimi (Herba Ocimi Pilosi) aerial parts 10Kg, clean, put in juice extractor and squeeze the juice, filter, obtain Herba Ocimi (Herba Ocimi Pilosi) juice 1.25Kg; Get Aloe 10Kg, clean, after skin upper and lower for Folium Aloe is removed, rinse the part after peeling a little with water, put in juice extractor and squeeze the juice, obtain Aloe juice 4.82Kg; Get Radix Arnebiae (Radix Lithospermi) and add alcohol reflux 3 each 8 times amount that volumetric concentration is 85%, filter, merge extractive liquid, reclaim ethanol, concentrate and make thick paste; Get Herba Ocimi (Herba Ocimi Pilosi) juice 1Kg, the Aloe juice 1Kg mixing of above-mentioned gained, Radix Arnebiae (Radix Lithospermi) thick paste 0.5kg respectively, stir, gained mixed liquor is loaded spray bottle and namely obtains a kind of Herba Ocimi (Herba Ocimi Pilosi) of the present invention, Aloe, Radix Arnebiae (Radix Lithospermi) thick paste composition gels spray.
Embodiment 3
Get fresh Herba Ocimi (Herba Ocimi Pilosi) aerial parts 10Kg, clean, put in juice extractor and squeeze the juice, filter, obtain Herba Ocimi (Herba Ocimi Pilosi) juice 1.25Kg; Get Aloe 10Kg, clean, after skin upper and lower for Folium Aloe is removed, rinse the part after peeling a little with water, put in juice extractor and squeeze, filter, obtain Aloe juice 4.82Kg; The Herba Ocimi (Herba Ocimi Pilosi) juice 1Kg and the Aloe juice 1Kg that get above-mentioned gained respectively mix, and stir, are dipped in mixed liquor by the non-woven fabrics of different area, make a kind of Herba Ocimi (Herba Ocimi Pilosi), aloe composition wet tissue.
Embodiment 4
Get fresh Herba Ocimi (Herba Ocimi Pilosi) aerial parts 2Kg to clean, chopping, adds the ethanol that 10Kg volumetric concentration is 85%, extract 2 hours in 50 DEG C, extract three times altogether, merge each filtrate, gained filtrate is placed in rotary evaporator concentrating under reduced pressure to original volume 1/5 time, stop evaporation, obtained Herba Ocimi extract (Herba Ocimi Pilosi extract); Get Aloe, clean, after skin upper and lower for Folium Aloe is removed, rinse the part after peeling a little with water, put in juice extractor and squeeze, filter, obtain Aloe juice; The Herba Ocimi extract (Herba Ocimi Pilosi extract) 1Kg and the Aloe juice 1.2Kg that get above-mentioned gained respectively mix, add 1g potassium sorbate, 2ml polyoxyethylene sorbitan monoleate stirs, then adds hydroxyethyl-cellulose 70g while stirring, to be mixed evenly after leave standstill and obtain a kind of Herba Ocimi (Herba Ocimi Pilosi) of the present invention, aloe composition ointment.
Embodiment 5 evaluating drug effect
For synergism when research raw materials used Herba Ocimi (Herba Ocimi Pilosi) of the present invention and Aloe share, and the potentiation of Radix Arnebiae extract, to treat mosquito bite curative effect and functions of detumescence, relieving inflammation effect for foundation, test as follows:
1. sample preparation:
Herba Ocimi (Herba Ocimi Pilosi) juice: get fresh Herba Ocimi (Herba Ocimi Pilosi) Herb 10Kg and clean, put in juice extractor and squeeze the juice, filter, obtain Herba Ocimi (Herba Ocimi Pilosi) juice 1.3Kg;
Aloe juice: get Aloe 10Kg, cleans, and after being removed by skin upper and lower for Folium Aloe, rinses the part after peeling a little, puts in juice extractor and squeeze, filter, obtain Aloe juice 4.9Kg with water;
Herba Ocimi (Herba Ocimi Pilosi) and Aloe juice mixture: the Herba Ocimi (Herba Ocimi Pilosi) juice 0.5Kg and the Aloe juice 0.5Kg that get above-mentioned gained respectively mix, and to obtain final product;
Herba Ocimi (Herba Ocimi Pilosi) and Aloe juice mixture add Radix Arnebiae extract: a, prepare Radix Arnebiae extract: get fresh Radix Arnebiae (Radix Lithospermi) Herb 0.5Kg and clean, chopping, the volumetric concentration adding 2Kg is the ethanol of 85%, extracts 2 hours in 50 DEG C, extracts three times altogether, merge each filtrate, gained filtrate is placed in rotary evaporator concentrating under reduced pressure to original volume 1/5 time, stop evaporation, obtained Radix Arnebiae extract; B, the basis of above-mentioned gained Herba Ocimi (Herba Ocimi Pilosi) and Aloe juice mixture adds Radix Arnebiae extract according to weight ratio 2:1, mix homogeneously and get final product.
2. mosquito bite therapeutic evaluation
2.1 experimental techniques: Subject Population is divided into three age brackets, be respectively 1-10 year, 11-20 year and more than 20 years old, use different laboratory samples stage by stage, sample is smeared immediately when mosquito bite, smeared every 15 minutes once until detumescence and till not itching, time after statistics medication effectively, smear number of times.Statistical result is in table 1.
Efficiently individual quantity statistical table (unit) tested by table 1
2.2 results show:
(1) for integral experiment crowd: in treatment mosquito bite, Herba Ocimi (Herba Ocimi Pilosi) and Aloe juice mixture, Herba Ocimi (Herba Ocimi Pilosi) and Aloe juice mixture add Radix Arnebiae extract, there is significant curative effect, compare Aloe juice, Herba Ocimi (Herba Ocimi Pilosi) juice is alone potentiation, and compositions obviously plays itching-relieving action when first time uses, onset is rapid, the problems such as position causes festers, infection that can prevent child (1-10 year) scratching from biting.
(2) for child (1-10 year): in treatment mosquito bite, Herba Ocimi (Herba Ocimi Pilosi) and Aloe juice mixture, Herba Ocimi (Herba Ocimi Pilosi) add Radix Arnebiae extract with Aloe juice mixture compared with Aloe juice, Herba Ocimi (Herba Ocimi Pilosi) juice is alone significant potentiation.
(3) for child (1-10 year): in treatment mosquito bite, Herba Ocimi (Herba Ocimi Pilosi) and Aloe juice mixture, Herba Ocimi (Herba Ocimi Pilosi) and Aloe juice mixture add Radix Arnebiae extract 100% can reach therapeutic purposes.
(4) for teenager (being greater than 10 years old): in treatment mosquito bite, Herba Ocimi (Herba Ocimi Pilosi) and Aloe juice mixture, Herba Ocimi (Herba Ocimi Pilosi) add Radix Arnebiae extract with Aloe juice mixture compared with Aloe juice, Herba Ocimi (Herba Ocimi Pilosi) juice are alone has significant potentiation when first time uses, after repeatedly using, difference is not quite.
(5) for child (1-10 year): in treatment mosquito bite, Herba Ocimi (Herba Ocimi Pilosi) add Radix Arnebiae extract with Aloe juice mixture compared with Herba Ocimi (Herba Ocimi Pilosi) have significant potentiation with Aloe juice mixture when smearing for the second time, main manifestations is detumescence aspect.
3. functions of detumescence, relieving inflammation evaluation of effect
3.1 experimental techniques:
Sample is adopted 2% compound Oleum Tiglii to be caused to the impact of mice ear
Get body weight healthy mice 50 (male and female half and half), be divided into 5 groups at random: Aloe juice group, Herba Ocimi (Herba Ocimi Pilosi) juice group, Herba Ocimi (Herba Ocimi Pilosi) and Aloe juice mixture group, Herba Ocimi (Herba Ocimi Pilosi) and Aloe juice mixture add Radix Arnebiae extract group, blank group (water matched group), 2% compound Oleum Tiglii 0.1ml uniform application is caused inflammation on mouse right ear two sides, after 3 hours, 5 groups of each 1ml uniform application of sample are left mice, auris dextra two sides, every 15 minutes 1 time, smear 4 times altogether, be that the card punch of 9mm pounds lower circular auricle at the same position of left-right ear with diameter after 1 hour, its weight is claimed by electronic balance essence, calculate its swelling degree and swelling rate.The results are shown in Table 2.
Swelling degree (mg)=auris dextra sheet heavy (mg)-left auricle heavy (mg)
Swelling rate (%)=[auris dextra sheet heavy (mg)-left auricle heavy (mg)] heavy (mg) × 100% of/left auricle
The different sample of table 2 causes the impact (n=10) of mice ear to 2% compound Oleum Tiglii
3.2 results show:
(1) in functions of detumescence, relieving inflammation, four groups of samples all have significant curative effect.
(2) in functions of detumescence, relieving inflammation, Herba Ocimi (Herba Ocimi Pilosi) and Aloe juice mixture, Herba Ocimi (Herba Ocimi Pilosi) add Radix Arnebiae extract with Aloe juice mixture compared with Aloe juice, Herba Ocimi (Herba Ocimi Pilosi) juice is alone potentiation.
Above two groups of experiments support the curative effect of this product in anti-mosquito bite and functions of detumescence, relieving inflammation by pharmacological experimental data.
4., because mosquito bite, eczema, comedo, acne or burn and scald etc. all need repellent antipruritic, therefore said composition is bitten at mosquito control, is all had beneficial effect in eczema, comedo, acne or burn and scald etc.Verify with regard to eczema, comedo, acne or burn and scald aspect respectively below:
4.1 eczema
Prepare Herba Ocimi (Herba Ocimi Pilosi) juice and Aloe juice according to the method in embodiment 1, mix according to Herba Ocimi (Herba Ocimi Pilosi) juice with Aloe juice weight ratio 1:1, for 100 routine eczema patients, using method is: every day is applied in eczema affected part three times, can uniform fold affected part be good with medicinal liquid.Therapeutic evaluation:
Recovery from illness: affected skin recovers normal, and kermesinus disappears.
Effective: pruritus disappears or micro-ly to itch, and affected skin does not spread, and the pruritus place of scratching scabs and comes off.
Effective: pruritus alleviates, affected skin do not spread or diffusion velocity slow.
Invalid: the state of an illness has no improvement.
Observed by clinical experiment and learn, Herba Ocimi (Herba Ocimi Pilosi) of the present invention, aloe mixture effectively can treat eczema, after smearing medicinal liquid, take effect in average 2 days, and use after 10 days, effective percentage reaches 90%, and cure rate reaches 83%.
Herba Ocimi (Herba Ocimi Pilosi) juice, Aloe juice and Radix Arnebiae extract is prepared according to the method for embodiment 3, and according to weight ratio 1:1:1 mixing, the routine eczema patients of clinical treatment 100 according to the method described above.
Result shows: of the present inventionly add the medicinal liquid after Radix Arnebiae extract, and treat after 10 days, effective percentage reaches 95%, and cure rate reaches 90%.
4.2 comedos, acne
Herba Ocimi (Herba Ocimi Pilosi) juice and Aloe juice is prepared according to the method in embodiment 1, mix with Aloe juice weight ratio 1:1 according to Herba Ocimi (Herba Ocimi Pilosi) juice, for 50 routine comedos, patients with acne, patient age interval is 14-25 year, affected part is distributed in face, the acne that shirtfront, back all have area not etc., using method is: smear affected part every day for three times, is good with uniform fold skin at every turn.
Therapeutic outcome: after patient smears medicinal liquid of the present invention, on average from the 5th day, comedo, acne are by red purpling gradually, finally dimmed, treat after 10 days, comedo, acne disappear, and after 15 days, skin recovers smooth, do not stay pox to print and skin sore, observe after 1 year, not recurrence.
4.3 burn and scald
Prepare Herba Ocimi (Herba Ocimi Pilosi) juice and Aloe juice according to the method in embodiment 1, mix according to Herba Ocimi (Herba Ocimi Pilosi) juice with Aloe juice weight ratio 1:1, treat 50 routine burned patients clinically, age distribution is 25-70 year, and administrated method is, more than a day secondary outer wiping or soak illing skin.
Therapeutic effect: burn and scald patients with mild, disappears in use medicinal liquid first day pain of the present invention, recovery from illness in 2 days; After moderate burned patient uses 2 days, pain disappears, recovery from illness in 2 weeks; Severe burned patient uses pain in 5 days to disappear, a recovery from illness in month, preventing from scar or slight trace after recovery from illness.The present invention is 94% to the effective percentage of burn and scald, and cure rate reaches 86%.
Embodiment 6 verifies Herba Ocimi (Herba Ocimi Pilosi) juice and the impact of Aloe juice mixture in anti-mosquito bite of different blended composition and division in a proportion
Herba Ocimi (Herba Ocimi Pilosi) juice and Aloe juice is prepared according to the method in embodiment 1, mix with Aloe juice weight ratio 1:1,1:2,1:3,1:4,2:1,3:1,4:1 according to Herba Ocimi (Herba Ocimi Pilosi) juice respectively, the age bracket of choice experiment crowd be 1-10 year, evaluate mosquito bite curative effect according to the sample using method described in embodiment 3.Statistical result is in table 3:
Efficiently individual quantity statistical table tested by table 3
Visible according to table 3, prepare Herba Ocimi (Herba Ocimi Pilosi) juice and Aloe juice according to the method in embodiment 1, when Herba Ocimi (Herba Ocimi Pilosi) juice and Aloe juice weight ratio are 3:1 ~ 1:2, curative effect is more or less the same, and curative effect is very remarkable, and other ratios also have obvious curative effects, but curative effect is on a declining curve.Prove by experiment, antipruritic fastest when ratio is 1:1.
Although illustrate and describe embodiments of the invention, those having ordinary skill in the art will appreciate that: can carry out multiple change, amendment, replacement and modification to these embodiments when not departing from principle of the present invention and aim, scope of the present invention is by claim and equivalents thereof.

Claims (10)

1. for subsiding a swelling, antipruritic, the Herba Ocimi (Herba Ocimi Pilosi) of antiinflammatory, an aloe composition, described Herba Ocimi (Herba Ocimi Pilosi), Aloe mass ratio are (1-10): (1-10).
2. according to claim 1 for subsiding a swelling, antipruritic, the Herba Ocimi (Herba Ocimi Pilosi) of antiinflammatory, aloe composition, it is characterized in that, described Herba Ocimi (Herba Ocimi Pilosi), Aloe mass ratio are (1-3): (1-2).
3. according to claim 2 for subsiding a swelling, antipruritic, the Herba Ocimi (Herba Ocimi Pilosi) of antiinflammatory, aloe composition, it is characterized in that, described Herba Ocimi (Herba Ocimi Pilosi), Aloe mass ratio are 1:1.
4. according to any one of claim 1-3 for subsiding a swelling, antipruritic, the Herba Ocimi (Herba Ocimi Pilosi) of antiinflammatory, aloe composition, it is characterized in that, described compositions also comprises the Radix Arnebiae (Radix Lithospermi) of 0.5-2 weight portion.
5. the detumescence described in any one of claim 1-3, antipruritic, the Herba Ocimi (Herba Ocimi Pilosi) of antiinflammatory, the preparation method of aloe composition, it is characterized in that, described Herba Ocimi (Herba Ocimi Pilosi) is by squeezing the juice or adopting solvent extraction to obtain Herba Ocimi extract (Herba Ocimi Pilosi extract), Herba Ocimi extract (Herba Ocimi Pilosi extract) and Aloe extract, by squeezing the juice after peeling or adopting solvent extraction to obtain Aloe extract, are mixed by described Aloe.
6. detumescence according to claim 4, antipruritic, the Herba Ocimi (Herba Ocimi Pilosi) of antiinflammatory, the preparation method of aloe composition, described Herba Ocimi (Herba Ocimi Pilosi) is by squeezing the juice or adopting solvent extraction to obtain Herba Ocimi extract (Herba Ocimi Pilosi extract), described Aloe is by squeezing the juice after peeling or adopting solvent extraction to obtain Aloe extract, described Radix Arnebiae (Radix Lithospermi) obtains Radix Arnebiae extract for adopting solvent extraction, described Radix Arnebiae extract and described Herba Ocimi extract (Herba Ocimi Pilosi extract) and Aloe extract is mixed.
7. the preparation method according to claim 5 or 6, is characterized in that, described extract all adopts volumetric concentration to be the ethanol extraction of 40-95%.
8. preparation method according to claim 7, is characterized in that, described extract all adopts volumetric concentration to be the ethanol extraction of 65-95%.
9. the application in the external preparation for skin medicine of preparation treatment mosquito bite, eczema, comedo, acne or burn and scald, externally-applied health-care products, cosmetics for external use, dissipation product or its additive of the Herba Ocimi (Herba Ocimi Pilosi) of the detumescence described in any one of claim 1-4, antipruritic, antiinflammatory, aloe composition.
10. according to application according to claim 9, it is characterized in that, described external preparation for skin medicine, externally-applied health-care products or cosmetics for external use are spray, gel, ointment, lotion, membrane or wet tissue.
CN201510908687.3A 2015-12-10 2015-12-10 A kind of sweet basil, aloe composition, preparation and its preparation method and application Active CN105287977B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510908687.3A CN105287977B (en) 2015-12-10 2015-12-10 A kind of sweet basil, aloe composition, preparation and its preparation method and application

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201510908687.3A CN105287977B (en) 2015-12-10 2015-12-10 A kind of sweet basil, aloe composition, preparation and its preparation method and application

Publications (2)

Publication Number Publication Date
CN105287977A true CN105287977A (en) 2016-02-03
CN105287977B CN105287977B (en) 2019-09-06

Family

ID=55186255

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201510908687.3A Active CN105287977B (en) 2015-12-10 2015-12-10 A kind of sweet basil, aloe composition, preparation and its preparation method and application

Country Status (1)

Country Link
CN (1) CN105287977B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116575234A (en) * 2023-05-24 2023-08-11 杭州优全生活科技股份有限公司 Degradable efficient degerming wet toilet paper and production process thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101342297A (en) * 2008-08-21 2009-01-14 太仓亚蕾生物制品有限公司 Acne removing aloe composition
CN101961376A (en) * 2010-07-23 2011-02-02 新疆医科大学 Method for refining sweet basil herb extract
CN102551574A (en) * 2010-12-23 2012-07-11 董世贤 Wild flower (basil) essential oil perfume wet towel
CN102755500A (en) * 2012-08-08 2012-10-31 董世贤 Basil ointment for treating scalding and preparation method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101342297A (en) * 2008-08-21 2009-01-14 太仓亚蕾生物制品有限公司 Acne removing aloe composition
CN101961376A (en) * 2010-07-23 2011-02-02 新疆医科大学 Method for refining sweet basil herb extract
CN102551574A (en) * 2010-12-23 2012-07-11 董世贤 Wild flower (basil) essential oil perfume wet towel
CN102755500A (en) * 2012-08-08 2012-10-31 董世贤 Basil ointment for treating scalding and preparation method thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
仇明: "《超级面膜全书》", 31 January 2010, 漓江出版社 *
马振友: "《最新皮肤科药物手册》", 30 June 2008, 世界图书出版西安公司 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116575234A (en) * 2023-05-24 2023-08-11 杭州优全生活科技股份有限公司 Degradable efficient degerming wet toilet paper and production process thereof
CN116575234B (en) * 2023-05-24 2023-11-21 杭州优全生活科技股份有限公司 Degradable efficient degerming wet toilet paper and production process thereof

Also Published As

Publication number Publication date
CN105287977B (en) 2019-09-06

Similar Documents

Publication Publication Date Title
CN101244221A (en) Composition for external application and preparation method
CN103479775B (en) Scraping liniment and preparation method thereof
CN105326730A (en) Acne-removing composition containing Chinese herb extracts and preparation method thereof
CN112190593B (en) Polysaccharide composition for inhibiting TRPV1 pathway and preparation method and application thereof
CN104147533A (en) Blood-activating, stasis-resolving and pain-relieving cream and preparation method thereof
CN103041042B (en) Tibetan medicine composition and application of composition in anti-off hair products
CN104857290A (en) Traditional Chinese medicine disinfection ointment for treating scalds and burns and preparation method thereof
CN104547303A (en) Externally used gel for treating gynecological inflammation and preparation method thereof
CN105497261A (en) Matrix of patch for external use and patch and sleeping-aid patch made from matrix
CN102266422A (en) Chinese medicinal preparation for treating slight and severe chilblains and production method thereof
CN100387291C (en) Medicine for treating pulmonary tuberculosis
CN105287977A (en) Sweet basil herb and aloe composition and preparation as well as preparation method and application of sweet basil herb and aloe composition
CN103845616A (en) Pharmaceutical composition for eliminating inflammation and disinfecting
CN110812377B (en) Acne treatment and repair composition and application thereof
CN103505398B (en) Forsythia leaf facial mask
CN105535820A (en) Mongolian medicine swelling subsidence ointment
CN106334176B (en) Chilblain ointment capable of relieving swelling, pain and itching and preparation method thereof
CN105106085A (en) Chinese medicinal herb sunscreen cream containing attapulgite
CN109248217A (en) A kind of paste and preparation method thereof for treating burn and scald
CN103341044A (en) Itching-relieving compound preparation and preparation method thereof
CN108354879A (en) A kind of aseptic face cream of anti-acne and preparation method thereof
CN105031223A (en) Chinese and western medicine compound preparation for treating eczema of external ear
CN105267577A (en) Paste for treating epidemic mumps and method for preparing paste
CN105343266A (en) Psoriasis treating ointment
CN105311370A (en) Preparation for treating electric burn and preparation process of preparation for treating electric burn

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant