CN106376927A - Health care product with auxiliary protective effect on chemical liver injury - Google Patents
Health care product with auxiliary protective effect on chemical liver injury Download PDFInfo
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- CN106376927A CN106376927A CN201610726692.7A CN201610726692A CN106376927A CN 106376927 A CN106376927 A CN 106376927A CN 201610726692 A CN201610726692 A CN 201610726692A CN 106376927 A CN106376927 A CN 106376927A
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- Prior art keywords
- root
- kudzu vine
- extract
- dendrobium candidum
- trifoliate orange
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The invention relates to a health care product with auxiliary protective effect on chemical liver injury. The health care product is composed of the following components by weight: 4-6 parts of Dendrobium officinale, 8-12 parts of kudzuvine root, and 7-10 parts of Hovenia dulcis Thunb. The herbal materials are subjected to water extraction, and then are dried and powdered, and the powder is made into a preparation. Main functional substances in Dendrobium officinale, kudzuvine root and Hovenia dulcis Thunb are extracted and blended to act on the liver from nourishing and protection two aspects by means of regulating human body microcirculation, therefore the health care product provided by the invention has significant auxiliary protective effect on chemical liver injury. At the same time, the employed herbal materials have mild drug properties, are scientifically and reasonably formulated, and have no toxic or side effect to human body. After extraction blending, the efficacy of the herbal materials can be better brought into play.
Description
Technical field
The present invention relates to a kind of health products, a kind of more particularly, to guarantor to chemical damage with auxiliary protection function
Strong product.
Background technology
Liver is maximum in digestion, most important digestion body of gland, is also predominant haematological organ and the people of fetus
The main metabolic organ of body and defence organ.Many adverse factor phases that it is external with human body and that metabolism produces meet with, and realize
Its powerful defence function of detoxification.While this defence adverse factor is to body damage, liver itself is also damaged unavoidably
Wound.These adverse factors include biological infection, the sense of for example each Hepatitis virus, various bacterium, parasite, protozoon etc.
Dye；The metabolic disorder that nutrition abnormal (lack or superfluous) or other reasonses cause, fatty liver that such as fat metabolism occurs extremely,
Jaundice that BILE PIGMENTS metabolic disorder causes etc.；Caused by work living environment, the harmful chemical of food, medicine and excessive drinking
Toxic hepatitis and its hepatic injury that classes such as cirrhosis and liver cancer may be developed into further.Hepatic injury is that liver is common
Pathologic process, a series of liver diseases thus the causing such as serious harm human health such as liver fibrosis, cirrhosis and liver tumour.
Hepatic injury is the common pathologic process of liver, a series of liver diseases such as liver fibrosis, cirrhosis thus causing
And the serious harm human health such as liver tumour.Hepatic injury mainly includes chemical damage and immunological liver injury.Chemically liver
Damage, be the hepatic injury caused by chemically Hepatoxic substance.These chemical substances include alcohol, the chemical toxicant in environment
And some drugses, they can cause cell membrane and enzyme to destroy, thus causing hepatic dysfunction, lead to hepatocellular apoptosis or
Necrosis, causes the obstacle of whole liver function further.The initial target site of chemical damage is all plasma membrane, and plasma membrane is once broken
Badly just cause chain reaction, form vicious circle.
All exist in the Nature and human industry's production process some to liver virose material, referred to as " close liver poison
Thing ", these poisonous substances are generally susceptible in crowd, and incubation period is short, and the process of pathology is directly related with the dosage of infection, can cause liver
Dirty different degrees of necrosis of liver cells, fat deformation, cirrhosis and liver cancer.It is showing improvement or progress day by day with social, living standards of the people
Raising, the change of dietary structure, because of bad eating habit (as excessively taken in high-fat food and excessive drinking etc.) in crowd
Dyslipidemia person increase year by year, leads to liver to be damaged in various degree.Exploitation has and has auxiliary protection to chemical damage
The health food of function is significant.
The exploitation of preventing and treating liver injury medicament makes great progress in recent years, but common drug is equal in preventing and treating hepatopathy
There are many deficiencies, particularly many medicines are also easy to produce rebeating phenomenon it is impossible to consolidate its therapeutic effect after discontinuing medication.In China
Herbal medicine has the experience of many preciousnesses in terms of preventing and treating hepatopathy, and at present, existing many Chinese herbal medicines are used for the preventing and treating of hepatopathy, and achieve
Curative effect well.
Content of the invention
The purpose of the present invention is for the deficiencies in the prior art, provides one kind effectively can have auxiliary to chemical damage
Protective effect and the health products having no side effect.
To achieve these goals, the present invention employs the following technical solutions：
A kind of health products to chemical damage with auxiliary protection function, obtain by the following method：
(1) will by weight：Dendrobium candidum 4-6 part, root of kudzu vine 8-12 part, trifoliate orange 7-10 part.Produce iron sheet stone respectively
Dry measure used in former times extract and the root of kudzu vine, trifoliate orange mixed extract.
(2), after said extracted liquid being mixed, concentrate in 65 DEG C of environment, under pressure of -0.07～-0.09Mpa vacuum,
Obtain medicinal material medicinal extract.
(3) by above-mentioned medicinal extract, by weight, add mannitol 2.4-3.6 part, be spray-dried, EAT
130-150 DEG C, 75-95 DEG C of leaving air temp, obtain medicinal material spray powder (moisture is less than or equal to 9wt%).
(4) above-mentioned spray powder is crossed 60 mesh sieves, obtain health products.
Further, the preparation method of described dendrobium candidum extract is as follows：First the dendrobium candidum of 1 weight portion is ground into
Meal, boils 3 times with the decocting of 30 weight portions, and decocting time is 3 hours, leaches liquid, the dregs of a decoction discard, and merges liquid, that is, obtains
Dendrobium candidum extract.
Further, the described root of kudzu vine, trifoliate orange mixed extract preparation method as follows：By the root of kudzu vine of 1 weight portion with
0.83 weight portion trifoliate orange mixing, boils 2 times with the decocting of 15 weight portions, decocting time is 1.5 hours, leaches liquid, the dregs of a decoction are abandoned
Go, merge liquid, that is, obtain the root of kudzu vine, trifoliate orange mixed extract.
Further, in described step 1, the skin stem of noble dendrobium, the root of kudzu vine, the mass ratio of trifoliate orange are 50:100:83.
Further, in described step 2, vacuum is -0.09Mpa.
Further, in described step 3, mannitol, by weight, is 3 parts.
Further, in affiliated step 3,140 DEG C of EAT, 85 DEG C of leaving air temp.
Beneficial effects of the present invention：To chemical damage, there is auxiliary protection function.
Specific embodiment
The present invention by dendrobium candidum, the root of kudzu vine, trifoliate orange through water extraction, be spray-dried, sieve, using prior art add auxiliary
Material, makes capsule, tablets.By adjust proportions' relation, and to wherein extraction process, be spray-dried carry out excellent
Change so that three achieves preferably collaborative raising effect, that is, after several medicinal materials combinations, its drug effect is with respect to when being used alone
Improve；Drug effect is more lasting；Produce unexpected effect in healthcare field.
Dendrobium candidum：Dendrobium candidum orchid family plant iron skin stem of noble dendrobium Dendrobium officinale involved in the present invention
Kimura et Migo is dried stem, also known as earrings dendrobium.It is sweet, be slightly cold, and returns stomach, kidney channel, has reinforcing stomach reg fluid, enriching yin clear
Hot the effect of, for pyreticosis Tianjin wound, dry polydipsia, deficiency of stomach-Yin, deficiency of food in vomitting, after being ill abnormal heat do not move back, fire excess from yin deficiency, hectic fever due to yin labor
Heat, mesh are secretly failed to understand, the disease such as muscles and bones impotence.Modern pharmacological research shows, it has stomach invigorating, promotes gastric secretion, antifatigue, enhancing
The effects such as immunologic function, anti-lipid peroxidation, suppression aldose reductase and regulation blood sugar.
The root of kudzu vine：The root of kudzu vine involved in the present invention is the drying of legume pueraria lobata Pueraria lobata (Willd.) Ohwi
Root.It is sweet, pungent, cool in nature, has expelling pathogenic factors from muscles and skin and brings down a fever, promotes the production of body fluid to quench thirst, promoting eruption, and Shengyang Zhixie is clearing and activating the channels and collaterals, deinebriating function.
Modern pharmacology research shows, the root of kudzu vine has suppression thrombus, improves microcirculation, protect cranial nerve, improve hepatic and renal function and resist
All multiactions such as oxidation.
Trifoliate orange：Trifoliate orange involved in the present invention is the drying of Rhamnaceae plant trifoliate orange Hovenia dulcis Thunb.
Mature seed.It is sweet, mild-natured, has a relieving restlessness of quenching the thirst, clearing away damp-heat, deinebriating effect, for alcoholism, polydipsia vomit inverse,
Difficulty in urination and defecation etc..Study of pharmacy shows that trifoliate orange has relieving alcoholism and protecting livers, anti-hepatic fibrosis and anti-aging, fatigue-resisting function.
The prescription foundation of the present invention：Incoordination between the liver and the spleen, how by stagnation of liver qi, perverse and unreasonable manner violates spleen to its card；Or because insufficiency of the spleen, ying blood is not
Foot, liver dysfunction and cause gastral cavity abdomen distending pain in the chest and hypochondrium, mental fatigue with loss of appetite, irregular menstruation, stomachache to have loose bowels, brothers unstable.Root of kudzu vine taste is pungent rises to be sent out,
Energy sending up the lucid yang, inspires the gas of taste sun clearly to rise and play the effect of antidiarrheal dysentery, is monarch drug in a prescription.Compatibility trifoliate orange, returns spleen warp, it is apt to relieve the effect of alcohol
Poison, is ministerial drug,《The southern regions of the Yunnan Province book on Chinese herbal medicine》Meaning：" control all left paralysed right paralysis, rheumatic numbness, energy relieving alcoholism；Or steep in wine and take it, also can relaxing muscles and tendons
Network, long term usage is made light of one's life by commiting suicide macrobiosis.Change children infantile malnutrition due to digestive disturbances or intestinalparasites worm, spleen is supported in stomach invigorating." help with the stem of noble dendrobium, grow stomach-Yin, clearing away the stomach-heat, control gastral cavity pain.Three medicine phases
Close, Shengyang Zhixie, spleen is supported in stomach invigorating, can be used for splenasthenic diarrhea, harmonizing the liver and spleen is got along well.
The acute toxicity test of the present invention：Press《Health food inspection and assessment technique specification》(version in 2003) carries out acute
Toxicity test, the not oral maximal tolerance dose of large and small mouse bisexuality is all higher than 15000mg/kg BW, is nontoxic level.
The micronucleus test of the present invention：Press《Health food inspection and assessment technique specification》(version in 2003) carries out micronucleus examination
Test, male and female mouse dose reaches 10000mg/kg b.wt., do not detect the cause micronucleus to male and female PCEMNR and make
With.
The sperm malformation test of the present invention：Press《Health food inspection and assessment technique specification》(version in 2003) carries out sperm
Deformity test, if tested material 2.5,5.0,3 dosage groups of 10.0g/kg bw, to male mice gavage.Tested material teratospermia
Result of the test is feminine gender.
The Salmonella reversion test of the present invention：Press《Health food inspection and assessment technique specification》(version in 2003) carries out Ames examination
Test, using flat board incorporation methods, dosage reaches 5000 μ g/ wares, plus and under the conditions of being not added with S9, to standard testing bacterial strain TA97a, TA98,
TA100 and TA102 does not all detect obvious MA.
30 days feeding trials of the rat of the present invention：Press《Health food inspection and assessment technique specification》(version in 2003) is carried out
30 days feeding trials of rat, sample is with 750,1500 and 3000mg/kg dosage (being equivalent to 25,50 and 100 times of recommended dose)
According to source board dendrobium candidum liver-protecting capsule mix basal feed in feed rat 30d, high dose group male and female rat actual absorption agent
Amount is respectively 3554,3414mg/kg (being equivalent to 118 and 113 times of recommended dose), and every tested index is not all detected substantially
Illeffects.
With reference to embodiment, the invention will be further described.
Embodiment 1
A kind of health products to chemical damage with auxiliary protection function, it obtains by the following method：
(1) extract preparation：
Dendrobium candidum extract：Dendrobium candidum 30 times amount decocting boils 3 times, 3 hours every time, leaches liquid, the dregs of a decoction discard, and obtain
To dendrobium candidum extract；Specific as follows shown：
Root of kudzu vine extract：The root of kudzu vine 8 times amount decocting boils 2 times, 1.5 hours every time, leaches liquid, the dregs of a decoction discard, obtain the root of kudzu vine,
Trifoliate orange extract.Specific as follows shown：
Trifoliate orange extract：Trifoliate orange 8 times amount decocting boils 2 times, 1.5 hours every time, leaches liquid, the dregs of a decoction discard, and obtain
The root of kudzu vine, trifoliate orange extract.Specific as follows shown：
Mixed extract：1 part of dendrobium candidum, is ground into meal, is boiled 3 times with 30 times amount decoctings, 3 hours every time, leaches medicine
Liquid, the dregs of a decoction discard, and obtain dendrobium candidum extract；After 1 part of the root of kudzu vine, 0.83 part of mixing of trifoliate orange, with 8 times of three's gross mass
The water yield decocts 2 times, 1.5 hours every time, leaches liquid, the dregs of a decoction discard, obtains the root of kudzu vine, trifoliate orange mixed extract；Then will be upper
State the mixing of two kinds of extracts, and dendrobium candidum, the root of kudzu vine and trifoliate orange material quality ratio is for 50:100:83, obtain mixed extract.
(2) said extracted liquid is concentrated respectively at 65 DEG C of environment, under pressure of -0.09Mpa vacuum, obtain medicinal material medicinal extract.
(3) above-mentioned medicinal extract is spray-dried respectively, 140 DEG C of EAT, 85 DEG C of leaving air temp, is obtained medicinal material spraying
Powder.
(4) above-mentioned spray powder is crossed 60 mesh sieves, respectively obtain dendrobium candidum, the root of kudzu vine, trifoliate orange seed extract and mixing and extract
Thing.
If solvent control group (pure water), above-mentioned four kinds of extracts and model control group are carried out following experiment：Each group fills
To sample, solvent control group and model control group give with isometric deionized water, once a day, continuous 30 days stomach.In examination
Test the 30th day, extract group and one group of gavage of model control group give 50% ethanol 15ml/kg b.wt., and volume control group gives
Water, take food 16h, puts to death animal and takes same position liver, make 5% liver tissue homogenate, measures TG content in homogenate with biochemical instruments.
Each group the results are shown in Table 1, and experimental result shows：The present invention have collaborative to chemical damage, there is auxiliary protection function effect,
I.e. effect effect of the present invention answers sum more than dendrobium candidum, the root of kudzu vine, trifoliate orange single-action.
Table 1 present invention and dendrobium candidum, the root of kudzu vine, the trifoliate orange list impact to triglycerides in mouse liver even slurry (TG) for the product
As can be seen from the table, in above-mentioned health products, dendrobium candidum, the root of kudzu vine, trifoliate orange after treatment, have and work in coordination with to change
The property learned hepatic injury has the function of auxiliary protection function, and its approach mainly has two：External approach, dendrobium candidum, the root of kudzu vine, trifoliate orange
Sub- extract is rich in the various active material such as polysaccharide material, Flavonoid substances, during mixing concentrate drying, intermolecular shape
Become hydrogen bond, glycosidic bond, ester bond or the fracture of ester bond connected group in moieties simultaneously, form covalent intermolecular bond, make the present invention
System stability is lifted and realizes working in coordination with has functions that auxiliary protection function to chemical damage；Internal approach, in vivo
The mainly effect to different target spots by each component, makes Interaction enhanced.Dendrobium candidum active component can remove internal from
By base, anti-lipid peroxidation, the expression of suppression TNF-α, in the person's serum that makes chemical damage and hepatic tissue, SOD substantially returns
Rise, and reduce the content of MDA, AST and ALT in serum and hepatic tissue.Root of kudzu vine active component can remove free radical, anti-lipid peroxy
Change, anti-fibrosis, rat blood serum aspartate amino transferase caused by carbon tetrachloride, phenylalanine ammonia group-transfer can be significantly reduced
Enzyme, the rising of hyaluronic acid contents, mitigate to hepatocellular pathologic lesion.Trifoliate orange active component can promote ethanol through ADH
Metabolism, hence it is evident that extending mouse sleeping duration, reduces blood concentration of alcohol, improves liver ADH activity, significantly alleviates continuous filling
The symptom such as hepatic steatosis that wine causes and liver cell enlargement, has effects of dispelling effects of alcohol and protecting liver.Dendrobium candidum, the root of kudzu vine, trifoliate orange
The multiple target spots in hepatic tissue metabolism network of relation can be simultaneously acted on, the monarch and his subjects' phase is helped, and realizes synergistic enhancing effect.Therefore, originally
Joint dendrobium candidum, the root of kudzu vine, trifoliate orange are passed through in invention, on the premise of ensureing respective medical value, create unexpected
Technique effect.
Embodiment 2：The present embodiment has been made to study further to the spray-drying process in preparation, and step is as follows：
(1) will by weight：1 part of dendrobium candidum, is ground into meal, is boiled 3 times with 30 times amount decoctings, 3 hours every time, filters
Go out liquid, the dregs of a decoction discard, obtain dendrobium candidum extract；After 1 part of the root of kudzu vine, 0.83 part of mixing of trifoliate orange, use three's gross mass
8 times of water yields decoct 2 times, 1.5 hours every time, leach liquid, the dregs of a decoction discard, obtain the root of kudzu vine, trifoliate orange mixed extract.
(2) after said extracted liquid being mixed, vacuum -0.09Mpa, 65 DEG C of environment, under pressure concentrate, and obtain medicinal material
Medicinal extract.
(3) above-mentioned medicinal extract is spray-dried, under the EAT shown in table 3,85 DEG C of leaving air temp, obtain medicinal material
Spray powder.
(4) above-mentioned spray powder is crossed 60 mesh sieves, obtain dendrobium candidum, the root of kudzu vine, trifoliate orange mixed atomizing powder.
Measure each group moisture, observe spray powder shape, acquired results are shown in Table 2.
Table 2 EAT to dendrobium candidum, the root of kudzu vine, trifoliate orange spray drying situation impact
As shown in Table 2, EAT is set to 130 DEG C -150 DEG C, obtains that powder rate is higher, and glutinous wall is less, and moisture is relatively low, and
The non-heated denaturalization of material, preferred scope is 130-150 DEG C.
Embodiment 3, the present embodiment has been made to study further to dendrobium candidum extraction process, and step is as follows：
(1) will by weight：1 part of dendrobium candidum is ground into meal.Factor level table according to set by table 3 is extracted,
Obtain dendrobium candidum extract.
(2), after said extracted liquid being mixed, concentrate in 65 DEG C of environment, under pressure of -0.09Mpa vacuum, obtain iron sheet
Stem of noble dendrobium medicinal extract.
With coarse polysaccharide extractive rate (%) as inspection target, from L9(34) table to decoct number of times (A), decocting time (B), plus
Three factors of the water yield (C) carry out orthogonal test, and each factor is all defined as three levels, are shown in Table 3, EE, experimental result and
Data processing is shown in Table 4, and analysis of variance table is shown in Table 5.
Table 3 orthogonal test factor level table
Table 4 L9(34) Orthogonal Experiment and Design and experimental result table
| Row number | A | B | C | D | Coarse polysaccharide extractive rate (%) |
| 1 | 1 | 1 | 1 | 1 | 3.5 |
| 2 | 1 | 2 | 2 | 2 | 5.3 |
| 3 | 1 | 3 | 3 | 3 | 6.2 |
| 4 | 2 | 1 | 2 | 3 | 9.4 |
| 5 | 2 | 2 | 3 | 1 | 10.2 |
| 6 | 2 | 3 | 1 | 2 | 9.5 |
| 7 | 3 | 1 | 3 | 2 | 13.2 |
| 8 | 3 | 2 | 1 | 3 | 12.3 |
| 9 | 3 | 3 | 2 | 1 | 13.4 |
| K1 | 5.000 | 8.700 | 8.433 | 9.033 | |
| K2 | 9.700 | 9.267 | 9.367 | 9.333 | |
| K3 | 12.967 | 9.700 | 9.867 | 9.300 | |
| R | 7.967 | 1.000 | 1.434 | 0.300 |
Table 5 analysis of variance table
Can be seen that from table 4, table 5：Extraction process largely have impact on the extraction of active component in dendrobium candidum
Rate, wherein influence degree are from large to small：Decoct number of times ＞ amount of water ＞ decocting time.K2 and k3 in view of factor A recovery rate
Difference is larger, selects 3 extractions；K2 and k3 in view of factor B, C recovery rate is more or less the same, and economic angle considers, selects water
30 times of amount, 3 hours selective extraction time.The preferred plan of extraction process is A3B2C2, that is,：Medicinal material adds 30 times amount decoctings and boils 3 times,
3 hours every time, preferable decoction effect can be obtained, medicinal material solid content recovery rate is higher and cost is relatively low.
Embodiment 4, the present embodiment has been made to study further to the root of kudzu vine, trifoliate orange extraction process, and step is as follows：
(1) will by weight：1 part of the root of kudzu vine, 0.83 part of trifoliate orange.Factor level table according to set by table 6 is extracted, and obtains
To the root of kudzu vine, trifoliate orange extract.
(2), after said extracted liquid being mixed, concentrate in 65 DEG C of environment, under pressure of -0.09Mpa vacuum, obtain iron sheet
Stem of noble dendrobium medicinal extract.
With general flavone (mg) as inspection target, from L9(34) table to decoct number of times (A), decocting time (B), amount of water (C)
Three factors carry out orthogonal test, and each factor is all defined as three levels, is shown in Table 3,
EE, experimental result and data processing are shown in Table 7, and analysis of variance table is shown in Table 8.
Table 6 orthogonal test factor level table
Table 7 L9(34) Orthogonal Experiment and Design and experimental result table
| Row number | A | B | C | D | Coarse polysaccharide extractive rate (%) |
| 1 | 1 | 1 | 1 | 1 | 67 |
| 2 | 1 | 2 | 2 | 2 | 84 |
| 3 | 1 | 3 | 3 | 3 | 93 |
| 4 | 2 | 1 | 2 | 3 | 135 |
| 5 | 2 | 2 | 3 | 1 | 143 |
| 6 | 2 | 3 | 1 | 2 | 146 |
| 7 | 3 | 1 | 3 | 2 | 152 |
| 8 | 3 | 2 | 1 | 3 | 153 |
| 9 | 3 | 3 | 2 | 1 | 159 |
| K1 | 81.333 | 118.000 | 122.000 | 123.000 | |
| K2 | 141.333 | 126.667 | 126.000 | 127.333 | |
| K3 | 154.667 | 132.667 | 129.333 | 127.000 | |
| R | 73.334 | 14.667 | 7.333 | 4.333 |
Table 8 analysis of variance table
Can be seen that from table 7, table 8：Extraction process largely have impact on the root of kudzu vine, active component carries in trifoliate orange
Take rate, wherein influence degree from large to small：Decoct number of times ＞ decocting time ＞ amount of water.Extract in view of factor A, B general flavone
K2 and K3 of rate is more or less the same, and selects 2 times to extract, 1.5 hours every time；Consider economical energy resources factor, select 8 times of the water yield.Extract
The preferred plan of technique is A2B2C1, that is,：Medicinal material adds 8 times amount decoctings and boils 2 times, 1.5 hours every time, can obtain preferable decoction and imitate
Really, medicinal material solid content recovery rate is higher and cost is relatively low.
Above example is used for explaining and the present invention being described, is not limited to the present invention, the ordinary skill of art
Personnel should be understood：Still the specific embodiment of the present invention can be modified or some technical characteristics are equal to
Replace, without deviating from the spirit of technical solution of the present invention, it all should cover the technical scheme scope being claimed in the present invention ought
In.
Claims (7)
1. a kind of health products to chemical damage with auxiliary protection function it is characterised in that：Obtain by the following method：
(1) will by weight：Dendrobium candidum 4-6 part, root of kudzu vine 8-12 part, trifoliate orange 7-10 part.Produce dendrobium candidum respectively to carry
Take liquid and the root of kudzu vine, trifoliate orange mixed extract.
(2), after said extracted liquid being mixed, concentrate in 65 DEG C of environment, under pressure of -0.07～-0.09Mpa vacuum, obtain
Medicinal material medicinal extract.
(3) mannitol 2.4-3.6 part will be added in above-mentioned medicinal extract, be spray-dried, 130-150 DEG C of EAT, go out wind-warm syndrome
75-95 DEG C of degree, obtains medicinal material spray powder.
(4) above-mentioned spray powder is crossed 60 mesh sieves, obtain health products.
2. health products according to claim 1 it is characterised in that：The preparation method of described dendrobium candidum extract is as follows：
First the dendrobium candidum of 1 weight portion is boiled 3 times with the decocting of 30 weight portions, decocting time is 3 hours about every time, leaches liquid,
The dregs of a decoction discard, and merge liquid, that is, obtain dendrobium candidum extract.
3. health products according to claim 1 it is characterised in that：The described root of kudzu vine, the preparation side of trifoliate orange mixed extract
Method is as follows：The root of kudzu vine of 1 weight portion is mixed with 0.83 weight portion trifoliate orange, boils 2 times with the decocting of 15 weight portions, decocting time is
1.5 hours, leach liquid, the dregs of a decoction discard, merge liquid, that is, obtain the root of kudzu vine, trifoliate orange mixed extract.
4. health products according to claim 1 it is characterised in that：In described step 1, dendrobium candidum, the root of kudzu vine, trifoliate orange
Mass ratio is 50:100:83.
5. health products according to claim 1 it is characterised in that：In described step 2, vacuum is -0.09Mpa.
6. health products according to claim 1 it is characterised in that：In described step 3, mannitol, by weight, is 3
Part.
7. health products according to claim 1 it is characterised in that：In described step 3,140 DEG C of EAT, leaving air temp
85℃.
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