CN106362201A - Medical hydrogel dressing material - Google Patents

Medical hydrogel dressing material Download PDF

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Publication number
CN106362201A
CN106362201A CN201610747962.2A CN201610747962A CN106362201A CN 106362201 A CN106362201 A CN 106362201A CN 201610747962 A CN201610747962 A CN 201610747962A CN 106362201 A CN106362201 A CN 106362201A
Authority
CN
China
Prior art keywords
parts
hydrogel
medical
weight
medical hydrogel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610747962.2A
Other languages
Chinese (zh)
Inventor
陆应生
苏情
王君
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GUILIN XINYI REFRIGERATION EQUIPMENT Co Ltd
Original Assignee
GUILIN XINYI REFRIGERATION EQUIPMENT Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GUILIN XINYI REFRIGERATION EQUIPMENT Co Ltd filed Critical GUILIN XINYI REFRIGERATION EQUIPMENT Co Ltd
Priority to CN201610747962.2A priority Critical patent/CN106362201A/en
Publication of CN106362201A publication Critical patent/CN106362201A/en
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/008—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0023—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0028—Polypeptides; Proteins; Degradation products thereof
    • A61L26/0038—Gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0028—Polypeptides; Proteins; Degradation products thereof
    • A61L26/0047—Specific proteins or polypeptides not covered by groups A61L26/0033 - A61L26/0042
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0057—Ingredients of undetermined constitution or reaction products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Materials For Medical Uses (AREA)

Abstract

The invention relates to a medical hydrogel dressing material. The medical hydrogel dressing material is prepared from the following materials in parts by weight: 20-30 parts of butyl cyanoacrylate, 4-6 parts of hydroquinone, 2-7 parts of propylene glycol, 7-10 parts of chitosan, 2-5 parts of sodium carboxymethylcellulose, and 6-10 parts of gelatin. The water absorption expansion rate of the product provided by the invention is higher than that of the conventional hydrogel material, in addition, after the hydrogel material is dried, the breaking strength of the hydrogel material is tested, the breaking strength of the hydrogel material is higher than that of the conventional hydrogel material, and moreover, the hydrogel dressing material provided by the invention has good biological compatibility.

Description

A kind of medical hydrogel dressings material
Technical field
The present invention relates to medical bio new material technology field, specifically a kind of medical hydrogel dressings material.
Background technology
Skin is the important barrier of human body, and all kinds of operations, wound, burn, dermatitis etc. all can lead to skin disruption and defect, Cause various wounds, repair in trauma is the key areas of medical development, sufferer is painful for mitigating, early recovery and keeping away It is excused from a college course scar after again to have great significance.
Content of the invention
The technical problem to be solved is to provide a kind of medical hydrogel dressings material.
The technical scheme is that a kind of medical hydrogel dressings material, by weight Meter includes:
The invention has the beneficial effects as follows: the expansion rate of water absorption of product of the present invention is higher than conventional hydrogel material, in addition will Hydrogel material determines its fracture strength after being dried, and its fracture strength obtains hydrogel material also above conventional, and the present invention Aerogel dressing material there is good bio-compatible.
On the basis of technique scheme, the present invention can also do following improvement.
Preferably, include by weight:
Preferably, also include the soybean protein powder of 5～12 weight portions.
Preferably, include by weight:
Include by weight:
Preferably, also include the described Aloe powder of 1～10 weight portion.
Specific embodiment
Embodiment 1
A kind of medical hydrogel dressings material, includes by weight: 25 parts of Tisuacryl, 6 parts of hydroquinone, 5 parts of propylene glycol, 10 parts of shitosan, 2 parts of sodium carboxymethyl cellulose and 7 parts of gelatin.
Each raw material is sequentially added in reactor, and is warming up to 65-85 DEG C, stir 10 minutes, be sufficiently mixed uniformly.
Embodiment 2
A kind of medical hydrogel dressings material, includes by weight: 25 parts of Tisuacryl, 6 parts of hydroquinone, 5 parts of propylene glycol, 10 parts of shitosan, 7 parts of gelatin, 3 parts of sodium carboxymethyl cellulose and 6 parts of soybean protein powder.
Each raw material is sequentially added in reactor, and is warming up to 65-85 DEG C, stir 10 minutes, be sufficiently mixed uniformly.
Embodiment 3
A kind of medical hydrogel dressings material, includes by weight: 35 parts of Tisuacryl, hydroquinone 5.5 Part, 5 parts of propylene glycol, 8 parts of shitosan, 7 parts of gelatin, 2 parts of sodium carboxymethyl cellulose and 6 parts of Aloe powder.
Each raw material is sequentially added in reactor, and is warming up to 65-85 DEG C, stir 10 minutes, be sufficiently mixed uniformly.
Embodiment 4
A kind of medical hydrogel dressings material, includes by weight: 35 parts of Tisuacryl, hydroquinone 5.5 Part, 5 parts of propylene glycol, 8 parts of shitosan, 7 parts of gelatin, 4 parts of sodium carboxymethyl cellulose and 7 parts of soybean protein powder.
Each raw material is sequentially added in reactor, and is warming up to 65-85 DEG C, stir 10 minutes, be sufficiently mixed uniformly.
To the biomaterial being obtained in embodiment 1-4 in the present invention, testing result is shown in Table down:
Expansion rate of water absorption (%) Fracture strength (mpa)
Embodiment 1 270 0.95
Embodiment 2 265 0.94
Embodiment 3 256 0.8
Embodiment 4 243 0.82
The expansion rate of water absorption of product of the present invention is higher than conventional hydrogel material, measures after in addition hydrogel material being dried Its fracture strength, its fracture strength is also above conventional hydrogel material, and the aerogel dressing material of the present invention has Good bio-compatible.
Although embodiments of the invention have been shown and described above it is to be understood that above-described embodiment is example Property it is impossible to be interpreted as limitation of the present invention, those of ordinary skill in the art within the scope of the invention can be to above-mentioned Embodiment is changed, changes, replacing and modification.

Claims (5)

1. a kind of medical hydrogel dressings material is it is characterised in that include by weight:
2. according to claim 1 a kind of medical hydrogel dressings material it is characterised in that including by weight:
3. according to claim 1 a kind of medical hydrogel dressings material it is characterised in that also including 5～12 weight portions Soybean protein powder.
4. according to claim 3 a kind of medical hydrogel dressings material it is characterised in that including by weight:
5. according to claim 1 a kind of medical hydrogel dressings material it is characterised in that also including 1～10 weight portion Aloe powder.
CN201610747962.2A 2016-08-29 2016-08-29 Medical hydrogel dressing material Pending CN106362201A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610747962.2A CN106362201A (en) 2016-08-29 2016-08-29 Medical hydrogel dressing material

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610747962.2A CN106362201A (en) 2016-08-29 2016-08-29 Medical hydrogel dressing material

Publications (1)

Publication Number Publication Date
CN106362201A true CN106362201A (en) 2017-02-01

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201610747962.2A Pending CN106362201A (en) 2016-08-29 2016-08-29 Medical hydrogel dressing material

Country Status (1)

Country Link
CN (1) CN106362201A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110538139A (en) * 2019-10-15 2019-12-06 南京林业大学 degradable supramolecular microgel/drug-loaded supramolecular microgel with electric activity and preparation method and application thereof
WO2021072661A1 (en) * 2019-10-15 2021-04-22 南京林业大学 Electroactive and degradable supramolecular microgel and drug-loaded supramolecular microgel, and preparation method and use thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1993411A (en) * 2004-07-30 2007-07-04 不列颠哥伦比亚大学 Method for producing hydrocolloid foams
CN104436288A (en) * 2014-11-10 2015-03-25 苏州蔻美新材料有限公司 Composite medical hydrogel dressing material and preparation method thereof
CN105056285A (en) * 2015-09-23 2015-11-18 广东泰宝医疗科技股份有限公司 Growth factor compound dressing capable of adhering tissue fissure and preparation method thereof
CN105617452A (en) * 2015-12-31 2016-06-01 佛山铭乾科技有限公司 Novel medical biological material
CN105770980A (en) * 2016-04-07 2016-07-20 苏州蔻美新材料有限公司 Medical adhesive and preparation method thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1993411A (en) * 2004-07-30 2007-07-04 不列颠哥伦比亚大学 Method for producing hydrocolloid foams
CN104436288A (en) * 2014-11-10 2015-03-25 苏州蔻美新材料有限公司 Composite medical hydrogel dressing material and preparation method thereof
CN105056285A (en) * 2015-09-23 2015-11-18 广东泰宝医疗科技股份有限公司 Growth factor compound dressing capable of adhering tissue fissure and preparation method thereof
CN105617452A (en) * 2015-12-31 2016-06-01 佛山铭乾科技有限公司 Novel medical biological material
CN105770980A (en) * 2016-04-07 2016-07-20 苏州蔻美新材料有限公司 Medical adhesive and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
方亮主编: "《药剂学第3版》", 31 March 2016, 中国医药科技出版社 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110538139A (en) * 2019-10-15 2019-12-06 南京林业大学 degradable supramolecular microgel/drug-loaded supramolecular microgel with electric activity and preparation method and application thereof
WO2021072661A1 (en) * 2019-10-15 2021-04-22 南京林业大学 Electroactive and degradable supramolecular microgel and drug-loaded supramolecular microgel, and preparation method and use thereof
CN110538139B (en) * 2019-10-15 2022-05-13 南京林业大学 Degradable supramolecular microgel/drug-loaded supramolecular microgel with electric activity and preparation method and application thereof

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Application publication date: 20170201

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