CN106361981A - 一种滋阴壮阳的中药 - Google Patents
一种滋阴壮阳的中药 Download PDFInfo
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- CN106361981A CN106361981A CN201610975544.9A CN201610975544A CN106361981A CN 106361981 A CN106361981 A CN 106361981A CN 201610975544 A CN201610975544 A CN 201610975544A CN 106361981 A CN106361981 A CN 106361981A
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Abstract
本发明涉及中药领域,具体地说是一种滋阴壮阳的中药。其由以下重量份数的各组分组成:蛇床子2‑7份、刺五加2‑7份、黄精2‑7份、淫羊霍2‑7份、肉苁蓉2‑7份、鹿茸2‑7份、麝香0.1‑0.5份、巴戟天2‑7份。本发明配伍科学,药物相辅相成,在治疗壮阳方面具有奇效。本发明采用纯中药制剂,天然无污染,无毒副作用,具有临床推广的价值。
Description
技术领域
本发明涉及中药领域,具体地说是一种滋阴壮阳的中药。
背景技术
目前,现有的滋阴壮阳中药均不同程度地存在着缺陷与不足,作用不明显,效果较差,且需多日连续服药,服药剂量大,药味怪异,易使服用者反感,治标不治里,不能从根本上医治人体的疾病或补偿人体的亏损或不足,长期服用对人体有不良作用。目前主治阳萎、早泄的新药大多以牛鞭、鹿鞭、人参、枸杞等十几种中药为原料配制成膏状,其用药时间长,见效慢,效果不明显,易生虚火,且食用不便。再者,壮阳中药为水剂中药,含防腐剂,对人体有害,药味苦、咸,极难人口,一般用盐引药入肾,以期达到速效的目的,实则损伤肾功能。
发明内容
本发明要解决的技术问题是如何克服现有技术的不足,提供一种测定花生叶片茉莉酸含量的方法。
本发明为实现上述目的采用的技术方案是:一种滋阴壮阳的中药,是由以下重量份数的各组分组成:蛇床子2-7份、刺五加2-7份、黄精2-7份、淫羊霍2-7份、肉苁蓉2-7份、鹿茸2-7份、麝香0.1-0.5份、巴戟天2-7份。
进一步的,本发明;另外一种方案是:包括以下重量份数的各组分组成:蛇床子2份、刺五加3份、黄精2份、淫羊霍4份、肉苁蓉3份、鹿茸2份、麝香0.3份、巴戟天4份。
进一步的,本发明在以上各种配方的基础上还包括以下重量份数的各组分组成:菟丝子2-7份,五味子2-7份,韭菜子2-7份,补骨脂2-7份,仙茅2-7份,何首乌2-7份,山萸肉2-7份,牛膝2-7份,党参2-7份,姜黄2-7份,苍耳子2-7份,白豆叩2-7份,鳖甲2-7份,麦冬2-7份,白芷2-7份,鸡血藤2-7份,白附子2-7份,肉桂2-7份,当归2-7份,川穹2-7份,甘草2-7份,虎杖2-7份,灵芝2-7份,木瓜2-7份,阳起石2-7份,钟乳石2-7份,磁石2-7份,朴硝2-7份。
进一步的,本发明还包括以下重量组份:菟丝子3份,五味子2份,韭菜子2份,补骨脂3份,仙茅4份,何首乌2份,山萸肉3份,牛膝2份,党参2份,姜黄2份,苍耳子2份,白豆叩3份,鳖甲2份,麦冬2份,白芷2份,鸡血藤3份,白附子4份,肉桂2份,当归3份,川穹2份,甘草5份,虎杖2份,灵芝2份,木瓜4份,阳起石2份,钟乳石4份,磁石2份,朴硝2份。
进一步的,上述药物的炮制过程如下:钟乳石2-7份、阳起石2-7份、磁石2-7份、朴硝2-7份研为细末,瓦上烘为赤色,冷却后加3倍量乙醇,在45-60℃条件下醇化48小时后,加3倍量水,蒸馏3-4小时,成为醇化水液备用。
更进一步的是上述药物的制备步骤:(1)、将除钟乳石、阳起石、磁石、朴硝之外的原料药分别粉碎,按磨成粉状,将磨粉放在发酵罐加入相当于磨粉重量1%发酵曲,再加醇化水液,搅拌均匀后,封闭发酵罐,于30℃放置3天,开封搅拌均匀,再密封,继续发酵4天,调节酸碱度为中性即可;(2)将发酵好的原料置入蒸馏罐中,加入发酵原料4倍量的水,于95-100℃下2小时,循环蒸馏三次,收集蒸馏三次的药液经200目过滤除渣,滤液进行浓缩烘干,得到药粉,再加入辅料得到成品。
进一步的,本发明还包括了上述的滋阴壮阳的中药与辅料制成任意中药剂型。
本发明配伍科学,药物相辅相成,在治疗壮阳方面具有奇效。本发明采用纯中药制剂,天然无污染,无毒副作用,具有临床推广的价值。
具体实施方式
下面对本发明提供的具体实施方式作详细说明。
本发明采用蛇床子、刺五加、黄精、淫羊霍、肉苁蓉、鹿茸、麝香、巴戟天、菟丝子,五味子,韭菜子,补骨脂,仙茅,何首乌,山萸肉,牛膝,党参,姜黄,苍耳子,白芷,白豆叩,鳖甲,麦冬,白芷,鸡血藤,白附子,肉桂,当归,川穹,甘草,虎杖,灵芝,木瓜,阳起石,钟乳石,磁石,朴硝以上的中药,其科学合理配伍,以上药物的具体药理作用如下:
蛇床子:性味:辛、苦,温;有小毒。归经:归肾经。功能主治:温肾壮阳,燥湿,祛风,杀虫。用于阳痿,宫冷,寒湿带下,湿痹腰痛;外治外阴湿疹,妇人阴痒;滴虫性阴道炎。
刺五加:性味:辛、微苦,温。归经:归脾、肾、心经。功能主治:益气健脾,补肾安神。用于脾肾阳虚,体虚乏力,食欲不振,腰膝酸痛,失眠多梦。
黄精:性味:甘,平。归经:归脾、肺、肾经。功能主治:补气养阴,健脾,润肺,益肾。用于脾胃虚弱,体倦乏力,口干食少,肺虚燥咳,精血不足,内热消渴。
淫羊霍:性味:辛、甘,温。归经:归肝、肾经。功能主治:补肾阳,强筋骨,祛风湿。用于阳痿遗精,筋骨痿软,风湿痹痛,麻木拘挛;更年期高血压。
肉苁蓉:性味:味甘;咸;性温。归经:归肾;大肠经。功能主治:补肾阳;益精血;润肠道。主肾阳虚衰;精血不足之阳痿;遗精;白浊;尿频余沥;腰痛脚弱;耳鸣目花;月经衍期;宫寒不孕;肠燥便秘。
鹿茸:气味:甘温无毒。主治:生精补髓.养血益阳.强筋健骨.补男子腰肾虚冷.脚膝无力.夜梦鬼交.精溢自出.女人崩中漏血.赤白带下.治一切虚损.耳聋目暗.眩晕虚痢.蜀中市上一道人货班龙丸.一名茸珠丹.大醉高歌曰.尾闾不禁沧海竭.九转灵丹都慢说.唯有班龙顶上珠.能补玉堂阙下穴.盖其方用鹿茸鹿角胶鹿角霜是也。
麝香:味辛,温,无毒。主辟恶气,杀鬼精物,温疟蛊毒,痫,去三虫,疗诸凶邪鬼气,中恶,心腹暴痛,胀急痞满,风毒,妇人产难,坠胎,去面(音孕)、目中肤翳。久服除邪,不梦寤魇寐,通神仙。生中台川谷及益州、雍州山中。春分取之,生者益良。
血。根:行气,活血,调经。用于月经不调,红崩,白带。
巴戟天:性味:甘,辛,微温。归经:归肾、肝经。功能主治:补肾阳,强筋骨,祛风湿。用于阳痿遗精,宫冷不孕,月经不调,少腹冷痛,风湿痹痛,筋骨痿软。
菟丝子:滋补肝肾、固精缩尿,安胎,明目,止泻。用于阳痿遗精、尿有余沥、遗尿尿频、腰膝酸软、目昏耳鸣、肾虚胎漏、胎动不安、脾肾胎漏、胎动不安、脾肾虚泻;外治白癜风。将原药筛去泥屑,拣去杂质,晒干。
五味子:性味:酸、甘,温。归经:归肺,心、肾经。功能主治:收敛固涩,益气生津,补肾宁心。用于久嗽虚喘,梦遗滑精,遗尿尿频,久泻不止,自汗,盗汗,津伤口渴,短气脉虚,内热消渴,心悸失眠。
韭菜子:性味:辛、甘,温。归经:归肝、肾经。功能主治:温补肝肾,壮阳固精。用于阳痿遗精,腰膝酸痛,遗尿尿频,白浊带下。
补骨脂:性味:辛、苦,温。归经:归肾、脾经。功能主治:温肾助阳,纳气,止泻。用于阳痿遗精,遗尿尿频,腰膝冷痛,肾虚作喘,五更泄泻;外用治白癜风,斑秃。
仙茅:性味:辛,热;有毒。归经:归肾、肝、脾经。功能主治:补肾阳,强筋骨,祛寒湿。用于阳痿精冷,筋骨痿软,腰膝冷痹,阳虚冷泻。
何首乌:性味:苦、甘、涩,温。归经:归肝、心、肾经。功能主治:解毒,消痈,润肠通便。用于瘰疠疮痈,风疹瘙痒,肠燥便秘;高血脂。
山萸肉:性味:酸、涩,微温。归经:归肝、肾经。功能主治:补益肝肾,涩精固脱。用于眩晕耳鸣,腰膝酸痛,阳痿遗精,遗尿尿频,崩漏带下,大汗虚脱。内热消渴。
牛膝:性味:甘、微苦,平。归经:归肝、肾经。功能主治:逐瘀通经,通利关节,利尿通淋。用于经闭症瘕,胞衣不下,关节痹痛,足痿筋挛,尿血血淋,跌扑损伤。
党参:性味:甘,平。归经:归脾、肺经。功能主治:补中益气,健脾益肺。用于脾肺虚弱,气短心悸,食少便溏,虚喘咳嗽,内热消渴。
姜黄:其味苦胜辛劣,辛香燥烈,性不应寒。…苦能泄热,辛能散结,故主心腹结积之属血分者。兼能治气,故又云下气。总其辛苦之力,破血除风热,消痈肿,其能事也。《日华子》谓其能治癥瘕血块,又通月经及扑损瘀血,苏颂谓其祛邪辟恶,治气胀及产后败血攻心,…何莫非下气破血辛走苦泄之功欤。察其气味治疗,乃介乎京三棱、郁金之药也。"
苍耳子:性味:甘,温,有毒。①《本经》:"味甘,温。"②《别录》:"苦。"③《品汇精要》:"味苦甘,性温,有小毒。"归经:入肺、肝经。①《雷公炮制药性解》:"入肺经。"②《玉楸药解》:"入足厥阴肝经。"③《本草求真》:"入肝、脾。"④《会约医镜》:"入肝、肾二经。"功能主治:散风,止痛,祛湿,杀虫。治风寒头痛,鼻渊,齿痛,风寒湿痹,四肢挛痛,疥癞,瘙痒。
白芷:性味:辛,温。归经:归胃、大肠、肺经。功能主治:散风除湿,通窍止痛,消肿排脓。用于感冒头痛,眉棱骨痛,鼻塞,鼻渊,牙痛,白带,疮疡肿痛。
白豆蔻:性味:辛,温。①《开宝本草》:"味辛,大温,无毒。"②《医学启源》:"气热,味大辛。"归经:入肺、脾经。①《汤液本草》:"入手太阴经。"②《雷公炮制药性解》:"入肺、脾、胃三经。"③《本草再新》:"入心、肝、脾三经。"功能主治:行气,暖胃,消食,宽中。治气滞,食滞,胸闷,腹胀,噫气,噎膈,吐逆,反胃,疟疾。
鳖甲:性味:咸,微寒。归经:归肝、肾经。功能主治:滋阴潜阳,软坚散结,退热除蒸。用于阴虚发热,劳热骨蒸,虚风内动,经闭,癓瘕,久疟疟母。
麦冬:性味:甘,微苦,微寒。归经:归心、肺、胃经。功能主治:养阴生津,润肺清心。用于肺燥干咳。虚痨咳嗽,津伤口渴,心烦失眠,内热消渴,肠燥便秘;咽白喉。
鸡血藤:性味:苦、甘,温。归经:归肝、肾经。功能主治:补血,活血,通络。用于月经不调,血虚萎黄,麻木瘫痪,风湿痹痛。
白附子:性味:辛,温;有毒。归经:归胃、肝经。功能主治:祛风痰,定惊搐,解毒散结止痛。用于中风痰壅,口眼歪斜,语言涩謇,痰厥头痛,偏正头痛,喉痹咽痛,破伤风;外治瘰疬痰核,毒蛇咬伤。
肉桂:性味:辛、甘,大热。归经:归肾、脾、心、肝经。功能主治:补火助阳,引火归源,散寒止痛,活血通经。用于阳痿,宫冷,腰膝冷痛,肾虚作喘,阳虚眩晕,目赤咽痛,心腹冷痛,虚寒吐泻,寒疝,奔豚,经闭,痛经。
当归:性味:甘、辛,温。归经:归肝、心、脾经。功能主治:补血活血,调经止痛,润肠通便。用于血虚萎黄,眩晕心悸,月经不调,经闭痛经,虚寒腹痛,肠燥便秘,风湿痹痛,跌扑损伤,痈疽疮疡。酒当归活血通经。用于经闭痛经,风湿痹痛,跌扑损伤。
川穹:性味:辛,温。归经:归肝、胆、心包经。功能主治:活血行气,祛风止痛。用于月经不调,经闭痛经,症瘕腹痛,胸胁刺痛,跌扑肿痛,头痛,风湿痹痛。
甘草:性味:甘,平。归经:归心、肺、脾、胃经。功能主治:补脾益气,清热解毒,祛痰止咳,缓急止痛,调和诸药。用于脾胃虚弱,倦怠乏力,心悸气短,咳嗽痰多,脘腹、四肢挛急疼痛,痈肿疮毒,缓解药物毒性、烈性。
虎杖:性味:微苦,微寒。归经:归肝、胆、肺经。功能主治:祛风利湿,散瘀定痛,止咳化痰。用于关节痹痛,湿热黄疸,经闭,症瘕,水火烫伤,跌扑损伤,痈肿疮毒,咳嗽痰多。
灵芝:性味:甘,平。归经:归心、肺、肝、肾经。功能主治:补气安神,止咳平喘。用于眩晕不眠,心悸气短,虚劳咳喘。
木瓜:性味:酸,温。归经:归肝、脾经。功能主治:平肝舒筋,和胃化湿。用于湿痹拘挛,腰膝关节酸重疼痛,吐泻转筋,脚气水肿。
阳起石:性味:甘,温。归经:入肾经。功能:温肾壮阳。主治:下焦虚寒,阳痿,遗精早泄,子宫寒冷不孕,腰膝酸软,崩漏等症。
钟乳石:性味:甘,温。归经:归肺、肾、胃经。功能主治:温肺,助阳,平喘,制酸,通乳。用于寒痰喘咳,阳虚冷喘,腰膝冷痛,胃痛泛酸,乳汁不通。
磁石:性味:咸,寒。归经:归肝、心、肾经。功能主治:平肝潜阳,聪耳明目,镇惊安神,纳气平喘。用于头晕目眩,视物昏花,耳鸣耳聋,惊悸失眠,肾虚气喘。
朴硝:味咸,微苦,性寒。禀天地寒水之气以结晶,水能胜火,寒能胜热,为心火炽盛有实热者之要药。疗心热生痰,精神迷乱、五心潮热,烦躁不眠。且咸能软坚,其性又善消,故能通大便燥结,化一切瘀滞。咸入血分,故又善消瘀血,治妊妇胎殇未下。
实施例1
将蛇床子2份、刺五加3份、黄精2份、淫羊霍4份、肉苁蓉3份、鹿茸2份、麝香0.3份、巴戟天4份原料药分别粉碎,按磨成粉状,将磨粉放在发酵罐加入相当于磨粉重量1%发酵曲,搅拌均匀后,封闭发酵罐,于30℃放置3天,开封搅拌均匀,再密封,继续发酵4天,调节酸碱度为中性即可;(2)将发酵好的原料置入蒸馏罐中,加入发酵原料4倍量的水,于95-100℃下2小时,循环蒸馏三次,收集蒸馏三次的药液经200目过滤除渣,滤液进行浓缩烘干,得到药粉,再加入辅料得到成品。
实施例2
(1)将钟乳石2份、阳起石2份、磁石2份、朴硝2份研为细末,瓦上烘为赤色,冷却后加3倍量乙醇,在45-60℃条件下醇化48小时后,加3倍量水,蒸馏3-4小时,成为醇化水液备用。
(2)、将蛇床子2份、刺五加3份、黄精2份、淫羊霍4份、肉苁蓉3份、鹿茸2份、麝香0.3份、巴戟天4份、菟丝子3份,五味子2份,韭菜子2份,补骨脂3份,仙茅4份,何首乌2份,山萸肉3份,牛膝2份,党参2份,姜黄2份,苍耳子2份,白芷2份,白豆叩3份,鳖甲2份,麦冬2份,鸡血藤3份,白附子4份,肉桂2份,当归3份,川穹2份,甘草5份,虎杖2份,灵芝2份,木瓜4份,阳起石2份,钟乳石4份,磁石2份,朴硝2份的原料药分别粉碎,按磨成粉状,将磨粉放在发酵罐加入相当于磨粉重量1%发酵曲,再加醇化水液,搅拌均匀后,封闭发酵罐,于30℃放置3天,开封搅拌均匀,再密封,继续发酵4天,调节酸碱度为中性即可;(2)将发酵好的原料置入蒸馏罐中,加入发酵原料4倍量的水,于95-100℃下2小时,循环蒸馏三次,收集蒸馏三次的药液经200目过滤除渣,滤液进行浓缩烘干,得到药粉,再加入辅料得到成品。
毒性试验:
实验动物
小白鼠由青岛市实验动物和动物实验中心提供。
小白鼠灌胃给药急性毒性实验
将30只小白鼠在实验室条件下适应性饲喂3d后,随机分成2组,每组15只,为实验组和对照组。禁食8h(不禁水)后,实验组给予如实施例1制备得到的本发明的中药片剂(将片剂溶解在水中获得混悬液)灌胃,对照组给予生理盐水灌胃。七日内观察灌胃后小白鼠的精神、行为、饮食欲等情况,记录小白鼠死亡时间和数量,剖检死亡小白鼠,观察各脏器组织的病理变化。实验结果表明七日内小白鼠无一死亡,处死小白鼠解剖观察各脏器未发现毒性反应,实验组与对照组小白鼠无任何差异。
大鼠灌胃给药长期毒性实验
毒性试验:
选取SD大鼠30只,分为对照组、实验组每组15只,雌雄各半。对照组采用生理盐水灌胃,实验组采用本实施例1片剂分散于水中,灌胃,剂量为6g(生药)·kg-1(相当于成人用药的100倍),一日三次灌胃,连续给药15周,观察动物一般情况及体重等指标。停药三天后,观察SD大鼠的毛发、行为、大小便、体重等指标,结果表明均无明显影响,脏器肉眼没有发现异样变化。处死大白鼠,对其内脏进行组织切片,电镜下表明无任何病变及异常。
疗效统计
经对能随访到的使用本发明壮阳药物进行饮用的用户进行跟踪调查,样本共计316例,每天服用,在服用1-2个月后,性功能有显著提高(性生活时间延长40%以上)的案例占83%。
以上所述仅是本发明的优选实施方式,应当指出,对于本技术领域的普通技术人员,在不脱离本发明方法的前提下,还可以做出若干改进和补充,这些改进和补充也应视为本发明的保护范围。
Claims (7)
1.一种滋阴壮阳的中药,其特征在于:是由以下重量份数的各组分组成:蛇床子2-7份、刺五加2-7份、黄精2-7份、淫羊霍2-7份、肉苁蓉2-7份、鹿茸2-7份、麝香0.1-0.5份、巴戟天2-7份。
2.根据权利要求1所述的一种滋阴壮阳的中药,其特征在于:包括以下重量份数的各组分组成:
蛇床子2份、刺五加3份、黄精2份、淫羊霍4份、肉苁蓉3份、鹿茸2份、麝香0.3份、巴戟天4份。
3.根据权利要求1或2所述的一种滋阴壮阳的中药,其特征在于:还包括以下重量份数的各组分组成:
菟丝子2-7份,五味子2-7份,韭菜子2-7份,补骨脂2-7份,仙茅2-7份,何首乌2-7份,山萸肉2-7份,牛膝2-7份,党参2-7份,姜黄2-7份,苍耳子2-7份,白芷2-7份,白豆叩2-7份,鳖甲2-7份,麦冬2-7份,鸡血藤2-7份,白附子2-7份,肉桂2-7份,当归2-7份,川穹2-7份,甘草2-7份,虎杖2-7份,灵芝2-7份,木瓜2-7份,阳起石2-7份,钟乳石2-7份,磁石2-7份,朴硝2-7份。
4.根据权利要求3所述的一种滋阴壮阳的中药,其特征在于:菟丝子3份,五味子2份,韭菜子2份,补骨脂3份,仙茅4份,何首乌2份,山萸肉3份,牛膝2份,党参2份,姜黄2份,苍耳子2份,白豆叩3份,鳖甲2份,麦冬2份,白芷2份,鸡血藤3份,白附子4份,肉桂2份,当归3份,川穹2份,甘草5份,虎杖2份,灵芝2份,木瓜4份,阳起石2份,钟乳石4份,磁石2份,朴硝2份。
5.根据权利要求1-4中任一项所述一种滋阴壮阳的中药,其特征在于:炮制过程如下:钟乳石2-7份、阳起石2-7份、磁石2-7份、朴硝2-7份研为细末,瓦上烘为赤色,冷却后加3倍量乙醇,在45-60℃条件下醇化48小时后,加3倍量水,蒸馏3-4小时,成为醇化水液备用。
6.根据权利要求1-5中任一项所述的一种滋阴壮阳的中药,其特征在于:其制备步骤:(1)、将除钟乳石、阳起石、磁石、朴硝之外的原料药分别粉碎,按磨成粉状,将磨粉放在发酵罐加入相当于磨粉重量1%发酵曲,再加醇化水液,搅拌均匀后,封闭发酵罐,于30℃放置3天,开封搅拌均匀,再密封,继续发酵4天,调节酸碱度为中性即可;(2)将发酵好的原料置入蒸馏罐中,加入发酵原料4倍量的水,于95-100℃下2小时,循环蒸馏三次,收集蒸馏三次的药液经200目过滤除渣,滤液进行浓缩烘干,得到药粉,再加入辅料得到成品。
7.包含如权利要求1所述的滋阴壮阳的中药与辅料制成任意中药剂型。
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