CN106360782A - Nutrient soft capsule dietary supplement having functions of preventing and repairing haze damage and preparation method thereof - Google Patents

Nutrient soft capsule dietary supplement having functions of preventing and repairing haze damage and preparation method thereof Download PDF

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Publication number
CN106360782A
CN106360782A CN201610719922.7A CN201610719922A CN106360782A CN 106360782 A CN106360782 A CN 106360782A CN 201610719922 A CN201610719922 A CN 201610719922A CN 106360782 A CN106360782 A CN 106360782A
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capsule
vitamin
haze
content
dietary supplement
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CN106360782B (en
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江波
张涛
陈静静
潘永胜
李宁
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Jiangnan University
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Jiangnan University
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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Abstract

A nutrient soft capsule dietary supplement having functions of preventing and repairing haze damage and a preparation method thereof, and belongs to the technical field of processing of health-caring products and foods. The dietary supplement includes a capsule and a capsule content. The capsule is prepared from a raw material, gel solution, which is composed of gelatin, glycerol, pure water and titanium dioxide according to the mass ratio of 50:20-30:50:1-2. Each 500 mg of the capsule content includes 5-20 [mu]g of vitamin D, 10-100 mg of vitamin E, 5-15 mg of [beta]-carotene, 10 mg of soya bean lecithin, and the balanced being olive oil and/or fish oil. The nutrient dietary soft capsule supplement has reasonable formula and simple preparation method and is rich in various high-effective anti-oxidizing nutrients, so that on the basis of satisfying daily demand of human body, the nutrient dietary soft capsule supplement can fully supply active substances having effects of interfering in haze damage and resisting oxidization, can effectively prevent and relieve oxidative stress reaction in respiratory tract due to pollutants in haze, and avoids incidence of various inflammations and even cardiovascular diseases and cancers caused by a reaction between reactive oxygen species and human body.

Description

A kind of have prevention and repair the nutrition cellulose soft capsules meal supplement that haze damages function Agent and preparation method thereof
Technical field
The present invention relates to a kind of have prevention and repair haze damage function nutrition cellulose soft capsules dietary supplement and its Preparation method, belongs to health-care food processing technique field.
Background technology
In recent years, China's haze pollution occurs again and again, and pollution range continuous enlargement is continuous by the number of haze pollution effect Increase.Although relevant departments have taken up measure and administer haze pollution, because haze is administered, required time is long, and regulation effect is not Can get instant result, haze pollution in a short time will not mitigate, people will continue to breathe contaminated air.Internal authority research institution Have confirmed air pollutants, especially pm2.5 particulate matter can cause the oxidative stress of human body, thus causing various respiratory tracts With dermatosis such as respiratory tract infection, asthma, bronchitis etc..Severe patient even affects cardiovascular health as hindered blood to follow Ring, initiation angina pectoriss, myocardial infarction, heart failure etc..Being exposed to the serious environment of air pollution for a long time can affect the life-span.Therefore Need to adopt an effective measure prevention and repair the damage that haze causes to human body.
At present, some authoritative research institutions look forward to (environment health in Environmental Health in the world Perspective) breathe and critical care medicine magazine (american journal of respiratory and with the U.S. Critical care medicine) etc. specialty research magazine publish thesis it is indicated that the various nutrient of meal supplement can be passed through As the fish oil rich in polyunsaturated fatty acid and olive oil, vitamin d, vitamin e and beta-carotene can effectively mitigate mist Haze damages.U.S. Environmental Protection Agency's research shows that the edible food rich in omega-3 polyunsaturated fatty acidses can alleviate air pollution to people The damage that body causes.Omega-3 polyunsaturated fatty acidses, by stimulating the reactive oxygen specieses (ros) producing to react with by haze granule, subtract Few adverse reaction to human body cell for the ros, thus reduce haze damage.Clinical experiment also confirms that, insatiable hunger more than the ω -3 in fish oil Superoxide dismutase in serum (sod) and glutathione sulfydryl transferase level can be improved with fatty acid, thus mitigating oxidation The damage that stress causes.An other research of this administration shows that olive oil also has and mitigates the function that haze damages.This is Because olive oil is rich in various vitamin and antioxidant, its excellent antioxidant activity contributes to improving endothelial function, reduces The blood pressure that haze particulate matter causes raises.King's College research in London finds, sucks experimenter's lung of more haze granule Vitamin e content in portion and blood is less, and indirect proof vitamin e plays in human body and mitigates the effect that haze damages.Its He also confirms that, vitamin e can mitigate inflammatory reaction and the oxidative stress of the vascular endothelial cell that haze causes at some researchs.Its He also has stronger non-oxidizability by antioxidant such as beta-carotene, is eaten for a long time and contributes to what enhancing body was damaged to haze Opposing and repair ability.Due to haze pollution also can vitamin d level in remote-effects human body, from food, additionally supplement dimension life Plain d is polluted the healthy very necessary of crowd for maintaining by haze.In sum, various nutrition can be supplemented by strengthening Have effect prevention and mitigate the damage to human body for the haze.
Because dietary habit is different, may not be met needed for pre- haze by the nutrient of food intake for each person every day.Cause This, the present invention develops a kind of dietary supplement rich in multiple anti-fog haze nutrients, simple and effective various anti-to human body offer Haze active substance.The present invention selects anti-fog haze activity and the stronger fat soluble nutrient of antioxidant activity, with rich in many insatiable hungers Prepare mixing soft capsule with the fish oil of fatty acid and/or olive oil for substrate.The mixotrophism cellulose soft capsules being produced are rich in multiple Effective ingredient, easily digested, bioavailability is high.This product formula rationally, is meeting needed for normal body On the basis of, provide anti-fog haze nutrient in a large number, with the injury preventing and mitigating everyday air pollution that human body is caused.Meanwhile, its In some compositions also have and improve immune system function, improve health, prophylaxis of cancer and prevent all kinds of cardiovascular disease Effect.Aceptable daily intake (ADI) (adi) that the content of various nutrients specifies less than Ministry of Public Health is it is ensured that the safety of product.At present There is no the mixotrophism element product that pre- haze is damaged on the market, it is blank that the present invention will fill up this.
Content of the invention
The purpose of the present invention is to mitigate the damage that haze pollution causes to health, provides a kind of component science, prevention With improve notable, instant the compound nutritional cellulose soft capsules dietary supplement of haze damage effect.
Technical scheme, a kind of have prevention and repair the nutrition cellulose soft capsules meal supplement that haze damages function Agent, including capsule and be included in the content in capsule;Described capsule raw material is glue, consists of gelatin glycerol pure water Titanium dioxide mass ratio is 50 20-30 50 1-2;In described content, in every 500mg content, contain 5-20 μ g vitamin d, 10-100mg vitamin e, 5-15mg beta-carotene, 10mg soybean lecithin, remaining is olive oil and/or fish oil, every glue Intracapsular content is 500 ± 50mg.
Containing 5-10 μ g vitamin d in described every 500mg content, 10-20mg vitamin e, 5-10mg beta-carotene, 10mg soybean lecithin, remaining is olive oil or fish oil.
Containing 5-10 μ g vitamin d in described every 500mg content, 10-20mg vitamin e, 5-10mg beta-carotene, 10mg soybean lecithin, remaining is the mass mixing thing such as olive oil and fish oil.
Described gelatin is animal gelatin.Described titanium dioxide is edible rank titanium dioxide.Described olive oil is extra virgin olive Olive oil.Described soybean lecithin is the concentrated soybean phospholipid of 60% content of phospholipid.
In described fish oil, dha and epa content is no less than the 50% of fish oil gross mass.
Described have prevention and repair the preparation method that haze damages the nutrition cellulose soft capsules dietary supplement of function, by weight Amount part meter step is as follows:
(1) glue preparation: prepare the glue for making capsule, glue material therefor is 50 parts of gelatin, glycerol 20-30 part is pure 50 parts of water purification and titanium dioxide 1-2 part;First 1-2 part titanium dioxide is mixed with 10 parts of glycerol, grind 25-35min and be obtained to mix and hang Supernatant liquid, adds 50 parts of pure water and remaining 10-20 part glycerol, stirs;Add 50 parts of gelatin particles, be heated to 65-70 DEG C, stirring 15-25min is complete to dissolving;Use 100 mesh screen, evacuation, vacuum≤- 0.08mpa under heat-retaining condition, take off Gas is standby;
(2) preparation of content: be made up of following nutrient by every 500mg content: 5-20 μ g vitamin d, 10-100mg dimension Raw element e, 5-15mg beta-carotene, 10mg soybean lecithin, remaining is olive oil and/or fish oil;First by fish oil and/or olive Olive oil is mixed with soybean lecithin, is sufficiently stirred for, and adds vitamin d, vitamin e and beta-carotene, stir in said mixture Mix 60min fully to dissolve, evacuation.Vacuum≤- 0.08mpa, degassing is stand-by;
(3) preparation of soft capsule: step (1) is prepared gained glue and prepares gained content warp on capsule machine with step (2) Pelleting makes soft capsule;Wherein glue box temperature 60-65 DEG C, every soft capsule contains 500 ± 50 mg contents;
(4) post processing: the soft capsule that step (3) is pressed into is placed in shape in rotating cage and 3h is dried, 22-25 DEG C of setting temperature is wet Degree 35%-45%;Subsequently qualitative dried capsule is placed in drying room is dried 36h, 28-31 DEG C of baking temperature, humidity 25%- 35%;Gained capsule is carried out selecting with ball, removes failure, packed with lighttight container, obtain product have prevention and Repair the nutrition cellulose soft capsules dietary supplement that haze damages function.
Beneficial effects of the present invention: the formula that the present invention provides rationally, rich in multiple high-efficiency antioxidant nutrients, is meeting Human body daily required on the basis of, fully supplement various have intervene haze damage and anti-oxidation function active substances, can Effectively prevent and improve the respiratory tract response to oxidative stress of haze pollutant initiation, thus avoiding the reactive oxygen specieses producing further Cause various inflammation or even cardiovascular disease and cancer with body reaction.
Specific embodiment
The present invention, including but not limited to following Examples are illustrated by following instance.
Embodiment 1
(1) glue preparation: glue material therefor and ratio be, gelatin glycerol pure water titanium dioxide weight ratio is for 50 20 50 1,1 part of titanium dioxide is mixed with 10 parts of glycerol, grinds and mixing suspension is obtained, add 50 parts of pure water and remaining 10 parts of glycerol, Stir.Add gelatin particle (50 parts), be heated to 65 DEG C.Stir to dissolving completely (about 25min), insulation is filtered, degassing Standby afterwards;
(2) preparation of content: every 500mg content is made up of following nutrient: 5 μ g vitamin d, 10mg vitamin e, 5mg Bata-carotene, 10mg soybean lecithin, remaining is olive oil.Collocation method is as follows: olive oil is mixed with soybean lecithin, fills Divide stirring.Add vitamin d, vitamin e, beta-carotene in said mixture, stirring 60min fully dissolves, and degassing is treated With;
(3) preparation of soft capsule: glue and content make soft capsule through pelleting on capsule machine.Glue box temperature 60 C, every Soft capsule content containing 500mg;
(4) post processing: the soft capsule being pressed into is placed in sizing (22 DEG C of temperature, humidity 40% ± 5%) in rotating cage and 3h is dried.It is placed in dry Dry (28 DEG C of temperature, humidity 30% ± 5%) is dried 36h.Again through selecting ball, remove failure.Wrapped with lighttight container Dress.
Embodiment 2:
(1) glue preparation: glue material therefor and ratio be, gelatin glycerol pure water titanium dioxide weight ratio is for 50 20 50 1,1 part of titanium dioxide is mixed with 10 parts of glycerol, grinds and mixing suspension is obtained, add 50 parts of pure water and remaining 10 parts of glycerol, Stir.Add gelatin particle (50 parts), be heated to 70 DEG C.Stir to dissolving completely (about 25min), insulation is filtered, degassing Standby afterwards.
(2) preparation of content: every 500mg content is made up of following nutrient: 10 μ g vitamin d, 20mg vitamin E, 10mg bata-carotene, 10mg soybean lecithin, remaining is olive oil.Collocation method is as follows: by olive oil and soybean lecithin Mixing, is sufficiently stirred for.Add vitamin d, vitamin e, beta-carotene in said mixture, stirring 60min fully dissolves, Degassing is stand-by.
(3) preparation of soft capsule: glue and content make soft capsule through pelleting on capsule machine.Glue box temperature 60-65 DEG C, every soft capsule content containing 500mg.
(4) post processing: the soft capsule being pressed into is placed in sizing (25 DEG C of temperature, humidity 40% ± 5%) in rotating cage and 3h is dried. It is placed in drying room (31 DEG C of temperature, humidity 30% ± 5%) and 36h is dried.Again through selecting ball, remove failure.Use lighttight container Packed.
Embodiment 3
(1) glue preparation: glue material therefor and ratio are that gelatin glycerol pure water titanium dioxide mass ratio is 50 20 50 1,1 part of titanium dioxide is mixed with 10 parts of glycerol, grinds and mixing suspension is obtained, add pure water and remaining 10 parts of glycerol, stirring Uniformly.Add gelatin particle (50 parts), be heated to 68 DEG C.Stir to dissolving completely (about 25min), insulation is filtered, deaerate standby With.
(2) preparation of content: every 500mg content is made up of following nutrient: 5 μ g vitamin d, 10mg vitamin E, 5mg bata-carotene, 10mg soybean lecithin, remaining is fish oil.Collocation method is as follows: fish oil mixed with soybean lecithin, It is sufficiently stirred for.Add vitamin d, vitamin e, beta-carotene in said mixture, stirring 60min fully dissolves, and degassing is treated With.
(3) preparation of soft capsule: glue and content make soft capsule through pelleting on capsule machine.Glue box temperature 60-65 DEG C, every soft capsule content containing 500mg.
(4) post processing: the soft capsule being pressed into is placed in sizing (23 DEG C of temperature, humidity 40% ± 5%) in rotating cage and 3h is dried.Put 36h is dried in drying room (30 DEG C of temperature, humidity 30% ± 5%).Again through selecting ball, remove failure.Entered with lighttight container Row packaging.
Embodiment 4
(1) glue preparation: glue material therefor and ratio are that gelatin glycerol pure water titanium dioxide mass ratio is 50 20 50 1,1 part of titanium dioxide is mixed with 10 parts of glycerol, grinds and mixing suspension is obtained, add pure water and remaining 10 parts of glycerol, stirring Uniformly.Add gelatin particle (50 parts), be heated to 66 DEG C.Stir to dissolving completely (about 25min), insulation is filtered, deaerate standby With.
(2) preparation of content: every 500mg content is made up of following nutrient: 10 μ g vitamin d, 20mg vitamin E, 10mg bata-carotene, 10mg soybean lecithin, remaining is fish oil.Collocation method is as follows: fish oil is mixed with soybean lecithin Close, be sufficiently stirred for.Add vitamin d, vitamin e, beta-carotene in said mixture, stirring 60min fully dissolves, and takes off Gas is stand-by.
(3) preparation of soft capsule: glue and content make soft capsule through pelleting on capsule machine.63 DEG C of glue box temperature, Every soft capsule content containing 500mg.
(4) post processing: the soft capsule being pressed into is placed in sizing (24 DEG C of temperature, humidity 40% ± 5%) in rotating cage and 3h is dried.Put 36h is dried in drying room (31 DEG C of temperature, humidity 30% ± 5%).Again through selecting ball, remove failure.Entered with lighttight container Row packaging.
Embodiment 5:
(1) glue preparation: glue material therefor and ratio are that gelatin glycerol pure water titanium dioxide mass ratio is 50 20 50 2,2 parts of titanium dioxides are mixed with 10 parts of glycerol, grinds and mixing suspension is obtained, add pure water and remaining 10 parts of glycerol, stirring Uniformly.Add gelatin particle (50 parts), be heated to 65 DEG C.Stir to dissolving completely (about 25min), insulation is filtered, deaerate standby With.
(2) preparation of content: every 500mg content is made up of following nutrient: 10 μ g vitamin d, 20mg vitamin E, 10mg bata-carotene, 10mg soybean lecithin, remaining is the mass mixing thing such as olive oil and fish oil.Collocation method is as follows: will Fish oil and olive oil are mixed with soybean lecithin, are sufficiently stirred for.Vitamin d, vitamin e, β-recklessly is added in said mixture Radix Raphani element, stirring 60min fully dissolves, and degassing is stand-by.
(3) preparation of soft capsule: glue and content make soft capsule through pelleting on capsule machine.Glue box temperature 60-65 DEG C, every soft capsule content containing 500mg.
(4) post processing: the soft capsule being pressed into is placed in sizing (25 DEG C of temperature, humidity 40% ± 5%) in rotating cage and 3h is dried.Put 36h is dried in drying room (28 DEG C of temperature, humidity 30% ± 5%).Again through selecting ball, remove failure.Entered with lighttight container Row packaging.

Claims (9)

1. a kind of have prevention and repair haze damage function nutrition cellulose soft capsules dietary supplement it is characterised in that: include Capsule and be included in the content in capsule;Described capsule raw material is glue, consists of gelatin glycerol pure water titanium white silty Amount ratio is 50 20-30 50 1-2;In described content, in every 500mg content, contain 5-20 μ g vitamin d, 10-100mg Vitamin e, 5-15mg beta-carotene, 10mg soybean lecithin, remaining is olive oil and/or fish oil;Interior in every capsule Tolerant is 500 ± 50mg.
2. there is prevention as claimed in claim 1 and repair the nutrition cellulose soft capsules dietary supplement that haze damages function, it is special Levy and be: containing 5-10 μ g vitamin d in described every 500mg content, 10-20mg vitamin e, 5-10mg beta-carotene, 10mg soybean lecithin, remaining is olive oil or fish oil.
3. there is prevention as claimed in claim 1 and repair the nutrition cellulose soft capsules dietary supplement that haze damages function, it is special Levy and be: containing 5-10 μ g vitamin d in described every 500mg content, 10-20mg vitamin e, 5-10mg beta-carotene, 10mg soybean lecithin, remaining is the mass mixing thing such as olive oil and fish oil.
4. there is prevention as claimed in claim 1 and repair the nutrition cellulose soft capsules dietary supplement that haze damages function, it is special Levy and be: described gelatin is animal gelatin.
5. there is prevention as claimed in claim 1 and repair the nutrition cellulose soft capsules dietary supplement that haze damages function, it is special Levy and be: described titanium dioxide is edible rank titanium dioxide.
6. there is prevention as claimed in claim 1 and repair the nutrition cellulose soft capsules dietary supplement that haze damages function, it is special Levy and be: described olive oil is Extra Virgin.
7. there is prevention as claimed in claim 1 and repair the nutrition cellulose soft capsules dietary supplement that haze damages function, it is special Levy and be: described soybean lecithin is the concentrated soybean phospholipid of 60% content of phospholipid.
8. there is prevention as claimed in claim 1 and repair the nutrition cellulose soft capsules dietary supplement that haze damages function, it is special Levy and be: in described fish oil, dha and epa content is no less than the 50% of fish oil gross mass.
9. there is described in claim 1 prevention and repair the preparation side that haze damages the nutrition cellulose soft capsules dietary supplement of function Method is it is characterised in that step by weight is as follows:
(1) glue preparation: prepare the glue for making capsule, glue material therefor is 50 parts of gelatin, glycerol 20-30 part is pure 50 parts of water purification and titanium dioxide 1-2 part;First 1-2 part titanium dioxide is mixed with 10 parts of glycerol, grind 25-35min and be obtained to mix and hang Supernatant liquid, adds 50 parts of pure water and remaining 10-20 part glycerol, stirs;Add 50 parts of gelatin particles, be heated to 65-70 DEG C, stirring 15-25min is complete to dissolving;Use 100 mesh screen, evacuation, vacuum≤- 0.08mpa under heat-retaining condition, take off Gas is standby;
(2) preparation of content: be made up of following nutrient by every 500mg content: 5-20 μ g vitamin d, 10-100mg dimension Raw element e, 5-15mg beta-carotene, 10mg soybean lecithin, remaining is olive oil and/or fish oil;First by fish oil and/or olive Olive oil is mixed with soybean lecithin, is sufficiently stirred for, and adds vitamin d, vitamin e and beta-carotene, stir in said mixture Mix 60min fully to dissolve, evacuation;Vacuum≤- 0.08mpa, degassing is stand-by;
(3) preparation of soft capsule: step (1) is prepared gained glue and prepares gained content warp on capsule machine with step (2) Pelleting makes soft capsule;Wherein glue box temperature 60-65 DEG C, every soft capsule content containing 500 ± 50mg;
(4) post processing: the soft capsule that step (3) is pressed into is placed in shape in rotating cage and 3h is dried, 22-25 DEG C of setting temperature is wet Degree 35%-45%;Subsequently qualitative dried capsule is placed in drying room is dried 36h, 28-31 DEG C of baking temperature, humidity 25%- 35%;Gained capsule is carried out selecting with ball, removes failure, packed with lighttight container, obtain product have prevention and Repair the nutrition cellulose soft capsules dietary supplement that haze damages function.
CN201610719922.7A 2016-08-25 2016-08-25 A kind of nutrition cellulose soft capsules dietary supplements for having the function of to prevent and repairing haze damage and preparation method thereof Active CN106360782B (en)

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CN107279976A (en) * 2017-07-01 2017-10-24 山东健康源生物工程有限公司 A kind of natural VE adds bata-carotene soft capsule and preparation method thereof

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107279976A (en) * 2017-07-01 2017-10-24 山东健康源生物工程有限公司 A kind of natural VE adds bata-carotene soft capsule and preparation method thereof

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