CN106360782A - Nutrient soft capsule dietary supplement having functions of preventing and repairing haze damage and preparation method thereof - Google Patents
Nutrient soft capsule dietary supplement having functions of preventing and repairing haze damage and preparation method thereof Download PDFInfo
- Publication number
- CN106360782A CN106360782A CN201610719922.7A CN201610719922A CN106360782A CN 106360782 A CN106360782 A CN 106360782A CN 201610719922 A CN201610719922 A CN 201610719922A CN 106360782 A CN106360782 A CN 106360782A
- Authority
- CN
- China
- Prior art keywords
- capsule
- vitamin
- haze
- content
- dietary supplement
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000007901 soft capsule Substances 0.000 title claims abstract description 50
- 230000006378 damage Effects 0.000 title claims abstract description 30
- 238000002360 preparation method Methods 0.000 title claims abstract description 28
- 235000015872 dietary supplement Nutrition 0.000 title claims abstract description 18
- 235000015097 nutrients Nutrition 0.000 title claims abstract description 18
- 230000006870 function Effects 0.000 title abstract description 10
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 72
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 claims abstract description 40
- 239000002775 capsule Substances 0.000 claims abstract description 24
- 235000021323 fish oil Nutrition 0.000 claims abstract description 24
- 239000004006 olive oil Substances 0.000 claims abstract description 24
- 235000008390 olive oil Nutrition 0.000 claims abstract description 24
- 229940046008 vitamin d Drugs 0.000 claims abstract description 23
- 108010010803 Gelatin Proteins 0.000 claims abstract description 21
- 239000008273 gelatin Substances 0.000 claims abstract description 21
- 229920000159 gelatin Polymers 0.000 claims abstract description 21
- 235000019322 gelatine Nutrition 0.000 claims abstract description 21
- 235000011852 gelatine desserts Nutrition 0.000 claims abstract description 21
- 239000004408 titanium dioxide Substances 0.000 claims abstract description 19
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 17
- 239000000047 product Substances 0.000 claims abstract description 6
- 239000002994 raw material Substances 0.000 claims abstract description 3
- 239000003292 glue Substances 0.000 claims description 33
- JLPULHDHAOZNQI-ZTIMHPMXSA-N 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCC\C=C/C\C=C/CCCCC JLPULHDHAOZNQI-ZTIMHPMXSA-N 0.000 claims description 24
- 229940083466 soybean lecithin Drugs 0.000 claims description 22
- 235000010215 titanium dioxide Nutrition 0.000 claims description 20
- 229940088594 vitamin Drugs 0.000 claims description 19
- 229930003231 vitamin Natural products 0.000 claims description 19
- 235000013343 vitamin Nutrition 0.000 claims description 19
- 239000011782 vitamin Substances 0.000 claims description 19
- 150000003722 vitamin derivatives Chemical class 0.000 claims description 19
- 230000002265 prevention Effects 0.000 claims description 18
- 239000001913 cellulose Substances 0.000 claims description 17
- 229920002678 cellulose Polymers 0.000 claims description 17
- 235000016709 nutrition Nutrition 0.000 claims description 17
- 230000008439 repair process Effects 0.000 claims description 17
- 238000003756 stirring Methods 0.000 claims description 17
- OENHQHLEOONYIE-UKMVMLAPSA-N all-trans beta-carotene Natural products CC=1CCCC(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C OENHQHLEOONYIE-UKMVMLAPSA-N 0.000 claims description 16
- 235000013734 beta-carotene Nutrition 0.000 claims description 16
- 239000011648 beta-carotene Substances 0.000 claims description 16
- TUPZEYHYWIEDIH-WAIFQNFQSA-N beta-carotene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)C=CC=C(/C)C=CC2=CCCCC2(C)C TUPZEYHYWIEDIH-WAIFQNFQSA-N 0.000 claims description 16
- 229960002747 betacarotene Drugs 0.000 claims description 16
- 230000035764 nutrition Effects 0.000 claims description 16
- OENHQHLEOONYIE-JLTXGRSLSA-N β-Carotene Chemical compound CC=1CCCC(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C OENHQHLEOONYIE-JLTXGRSLSA-N 0.000 claims description 16
- 238000002156 mixing Methods 0.000 claims description 10
- 239000000203 mixture Substances 0.000 claims description 10
- 238000007872 degassing Methods 0.000 claims description 8
- 239000000463 material Substances 0.000 claims description 7
- 238000000034 method Methods 0.000 claims description 7
- 239000002245 particle Substances 0.000 claims description 7
- 238000012805 post-processing Methods 0.000 claims description 7
- 238000001035 drying Methods 0.000 claims description 6
- 240000007817 Olea europaea Species 0.000 claims description 3
- 241001465754 Metazoa Species 0.000 claims description 2
- 239000007788 liquid Substances 0.000 claims description 2
- 150000003904 phospholipids Chemical class 0.000 claims description 2
- 238000000746 purification Methods 0.000 claims description 2
- 239000008347 soybean phospholipid Substances 0.000 claims description 2
- 239000006228 supernatant Substances 0.000 claims description 2
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 abstract description 10
- 230000000694 effects Effects 0.000 abstract description 9
- 239000013589 supplement Substances 0.000 abstract description 7
- 229930003427 Vitamin E Natural products 0.000 abstract description 5
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 abstract description 5
- 235000019165 vitamin E Nutrition 0.000 abstract description 5
- 229940046009 vitamin E Drugs 0.000 abstract description 5
- 239000011709 vitamin E Substances 0.000 abstract description 5
- 235000013305 food Nutrition 0.000 abstract description 4
- 208000024172 Cardiovascular disease Diseases 0.000 abstract description 3
- 206010061218 Inflammation Diseases 0.000 abstract description 3
- 239000013543 active substance Substances 0.000 abstract description 3
- 230000004054 inflammatory process Effects 0.000 abstract description 3
- 210000002345 respiratory system Anatomy 0.000 abstract description 3
- 230000003064 anti-oxidating effect Effects 0.000 abstract description 2
- 201000011529 cardiovascular cancer Diseases 0.000 abstract description 2
- 238000006243 chemical reaction Methods 0.000 abstract description 2
- 239000003344 environmental pollutant Substances 0.000 abstract description 2
- 238000007254 oxidation reaction Methods 0.000 abstract description 2
- 231100000719 pollutant Toxicity 0.000 abstract description 2
- 238000012545 processing Methods 0.000 abstract description 2
- 230000011506 response to oxidative stress Effects 0.000 abstract description 2
- 235000005911 diet Nutrition 0.000 abstract 2
- 230000000378 dietary effect Effects 0.000 abstract 2
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 abstract 1
- 244000068988 Glycine max Species 0.000 abstract 1
- 235000010469 Glycine max Nutrition 0.000 abstract 1
- 229930003316 Vitamin D Natural products 0.000 abstract 1
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 abstract 1
- 239000000499 gel Substances 0.000 abstract 1
- 230000002452 interceptive effect Effects 0.000 abstract 1
- 235000010445 lecithin Nutrition 0.000 abstract 1
- 239000000787 lecithin Substances 0.000 abstract 1
- 229940067606 lecithin Drugs 0.000 abstract 1
- 239000003642 reactive oxygen metabolite Substances 0.000 abstract 1
- 235000019166 vitamin D Nutrition 0.000 abstract 1
- 239000011710 vitamin D Substances 0.000 abstract 1
- 150000003710 vitamin D derivatives Chemical class 0.000 abstract 1
- 238000011160 research Methods 0.000 description 7
- 238000009413 insulation Methods 0.000 description 5
- 238000004513 sizing Methods 0.000 description 5
- 239000000725 suspension Substances 0.000 description 5
- 230000003078 antioxidant effect Effects 0.000 description 4
- 238000003915 air pollution Methods 0.000 description 3
- 230000036541 health Effects 0.000 description 3
- 235000012054 meals Nutrition 0.000 description 3
- 238000004806 packaging method and process Methods 0.000 description 3
- 239000003963 antioxidant agent Substances 0.000 description 2
- 235000006708 antioxidants Nutrition 0.000 description 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 229940124446 critical care medicine Drugs 0.000 description 2
- 230000002354 daily effect Effects 0.000 description 2
- 235000014113 dietary fatty acids Nutrition 0.000 description 2
- 230000003203 everyday effect Effects 0.000 description 2
- 239000000194 fatty acid Substances 0.000 description 2
- 229930195729 fatty acid Natural products 0.000 description 2
- 150000004665 fatty acids Chemical class 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- RWSXRVCMGQZWBV-WDSKDSINSA-N glutathione Chemical compound OC(=O)[C@@H](N)CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O RWSXRVCMGQZWBV-WDSKDSINSA-N 0.000 description 2
- 239000008187 granular material Substances 0.000 description 2
- 235000003642 hunger Nutrition 0.000 description 2
- 230000000977 initiatory effect Effects 0.000 description 2
- 230000000116 mitigating effect Effects 0.000 description 2
- 235000020660 omega-3 fatty acid Nutrition 0.000 description 2
- 230000036542 oxidative stress Effects 0.000 description 2
- 239000001301 oxygen Substances 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- 239000013618 particulate matter Substances 0.000 description 2
- 241000894007 species Species 0.000 description 2
- 206010067484 Adverse reaction Diseases 0.000 description 1
- 206010002383 Angina Pectoris Diseases 0.000 description 1
- 206010048768 Dermatosis Diseases 0.000 description 1
- 108010024636 Glutathione Proteins 0.000 description 1
- 206010019280 Heart failures Diseases 0.000 description 1
- 206010020466 Hunger Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 206010057190 Respiratory tract infections Diseases 0.000 description 1
- 102000019197 Superoxide Dismutase Human genes 0.000 description 1
- 108010012715 Superoxide dismutase Proteins 0.000 description 1
- 102000004357 Transferases Human genes 0.000 description 1
- 108090000992 Transferases Proteins 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000006838 adverse reaction Effects 0.000 description 1
- 239000000809 air pollutant Substances 0.000 description 1
- 231100001243 air pollutant Toxicity 0.000 description 1
- 239000008047 antioxidant nutrient Substances 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 206010006451 bronchitis Diseases 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 230000036996 cardiovascular health Effects 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 235000006694 eating habits Nutrition 0.000 description 1
- 230000008753 endothelial function Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 230000005183 environmental health Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 235000019197 fats Nutrition 0.000 description 1
- 230000037406 food intake Effects 0.000 description 1
- 235000012631 food intake Nutrition 0.000 description 1
- 229960003180 glutathione Drugs 0.000 description 1
- 210000000987 immune system Anatomy 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 239000003595 mist Substances 0.000 description 1
- 208000010125 myocardial infarction Diseases 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- SOQBVABWOPYFQZ-UHFFFAOYSA-N oxygen(2-);titanium(4+) Chemical class [O-2].[O-2].[Ti+4] SOQBVABWOPYFQZ-UHFFFAOYSA-N 0.000 description 1
- 235000020777 polyunsaturated fatty acids Nutrition 0.000 description 1
- 238000011321 prophylaxis Methods 0.000 description 1
- 230000005180 public health Effects 0.000 description 1
- 230000000241 respiratory effect Effects 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 230000035882 stress Effects 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 210000003556 vascular endothelial cell Anatomy 0.000 description 1
- -1 vitamin d Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Medicinal Preparation (AREA)
- General Preparation And Processing Of Foods (AREA)
Abstract
A nutrient soft capsule dietary supplement having functions of preventing and repairing haze damage and a preparation method thereof, and belongs to the technical field of processing of health-caring products and foods. The dietary supplement includes a capsule and a capsule content. The capsule is prepared from a raw material, gel solution, which is composed of gelatin, glycerol, pure water and titanium dioxide according to the mass ratio of 50:20-30:50:1-2. Each 500 mg of the capsule content includes 5-20 [mu]g of vitamin D, 10-100 mg of vitamin E, 5-15 mg of [beta]-carotene, 10 mg of soya bean lecithin, and the balanced being olive oil and/or fish oil. The nutrient dietary soft capsule supplement has reasonable formula and simple preparation method and is rich in various high-effective anti-oxidizing nutrients, so that on the basis of satisfying daily demand of human body, the nutrient dietary soft capsule supplement can fully supply active substances having effects of interfering in haze damage and resisting oxidization, can effectively prevent and relieve oxidative stress reaction in respiratory tract due to pollutants in haze, and avoids incidence of various inflammations and even cardiovascular diseases and cancers caused by a reaction between reactive oxygen species and human body.
Description
Technical field
The present invention relates to a kind of have prevention and repair haze damage function nutrition cellulose soft capsules dietary supplement and its
Preparation method, belongs to health-care food processing technique field.
Background technology
In recent years, China's haze pollution occurs again and again, and pollution range continuous enlargement is continuous by the number of haze pollution effect
Increase.Although relevant departments have taken up measure and administer haze pollution, because haze is administered, required time is long, and regulation effect is not
Can get instant result, haze pollution in a short time will not mitigate, people will continue to breathe contaminated air.Internal authority research institution
Have confirmed air pollutants, especially pm2.5 particulate matter can cause the oxidative stress of human body, thus causing various respiratory tracts
With dermatosis such as respiratory tract infection, asthma, bronchitis etc..Severe patient even affects cardiovascular health as hindered blood to follow
Ring, initiation angina pectoriss, myocardial infarction, heart failure etc..Being exposed to the serious environment of air pollution for a long time can affect the life-span.Therefore
Need to adopt an effective measure prevention and repair the damage that haze causes to human body.
At present, some authoritative research institutions look forward to (environment health in Environmental Health in the world
Perspective) breathe and critical care medicine magazine (american journal of respiratory and with the U.S.
Critical care medicine) etc. specialty research magazine publish thesis it is indicated that the various nutrient of meal supplement can be passed through
As the fish oil rich in polyunsaturated fatty acid and olive oil, vitamin d, vitamin e and beta-carotene can effectively mitigate mist
Haze damages.U.S. Environmental Protection Agency's research shows that the edible food rich in omega-3 polyunsaturated fatty acidses can alleviate air pollution to people
The damage that body causes.Omega-3 polyunsaturated fatty acidses, by stimulating the reactive oxygen specieses (ros) producing to react with by haze granule, subtract
Few adverse reaction to human body cell for the ros, thus reduce haze damage.Clinical experiment also confirms that, insatiable hunger more than the ω -3 in fish oil
Superoxide dismutase in serum (sod) and glutathione sulfydryl transferase level can be improved with fatty acid, thus mitigating oxidation
The damage that stress causes.An other research of this administration shows that olive oil also has and mitigates the function that haze damages.This is
Because olive oil is rich in various vitamin and antioxidant, its excellent antioxidant activity contributes to improving endothelial function, reduces
The blood pressure that haze particulate matter causes raises.King's College research in London finds, sucks experimenter's lung of more haze granule
Vitamin e content in portion and blood is less, and indirect proof vitamin e plays in human body and mitigates the effect that haze damages.Its
He also confirms that, vitamin e can mitigate inflammatory reaction and the oxidative stress of the vascular endothelial cell that haze causes at some researchs.Its
He also has stronger non-oxidizability by antioxidant such as beta-carotene, is eaten for a long time and contributes to what enhancing body was damaged to haze
Opposing and repair ability.Due to haze pollution also can vitamin d level in remote-effects human body, from food, additionally supplement dimension life
Plain d is polluted the healthy very necessary of crowd for maintaining by haze.In sum, various nutrition can be supplemented by strengthening
Have effect prevention and mitigate the damage to human body for the haze.
Because dietary habit is different, may not be met needed for pre- haze by the nutrient of food intake for each person every day.Cause
This, the present invention develops a kind of dietary supplement rich in multiple anti-fog haze nutrients, simple and effective various anti-to human body offer
Haze active substance.The present invention selects anti-fog haze activity and the stronger fat soluble nutrient of antioxidant activity, with rich in many insatiable hungers
Prepare mixing soft capsule with the fish oil of fatty acid and/or olive oil for substrate.The mixotrophism cellulose soft capsules being produced are rich in multiple
Effective ingredient, easily digested, bioavailability is high.This product formula rationally, is meeting needed for normal body
On the basis of, provide anti-fog haze nutrient in a large number, with the injury preventing and mitigating everyday air pollution that human body is caused.Meanwhile, its
In some compositions also have and improve immune system function, improve health, prophylaxis of cancer and prevent all kinds of cardiovascular disease
Effect.Aceptable daily intake (ADI) (adi) that the content of various nutrients specifies less than Ministry of Public Health is it is ensured that the safety of product.At present
There is no the mixotrophism element product that pre- haze is damaged on the market, it is blank that the present invention will fill up this.
Content of the invention
The purpose of the present invention is to mitigate the damage that haze pollution causes to health, provides a kind of component science, prevention
With improve notable, instant the compound nutritional cellulose soft capsules dietary supplement of haze damage effect.
Technical scheme, a kind of have prevention and repair the nutrition cellulose soft capsules meal supplement that haze damages function
Agent, including capsule and be included in the content in capsule;Described capsule raw material is glue, consists of gelatin glycerol pure water
Titanium dioxide mass ratio is 50 20-30 50 1-2;In described content, in every 500mg content, contain 5-20 μ g vitamin d,
10-100mg vitamin e, 5-15mg beta-carotene, 10mg soybean lecithin, remaining is olive oil and/or fish oil, every glue
Intracapsular content is 500 ± 50mg.
Containing 5-10 μ g vitamin d in described every 500mg content, 10-20mg vitamin e, 5-10mg beta-carotene,
10mg soybean lecithin, remaining is olive oil or fish oil.
Containing 5-10 μ g vitamin d in described every 500mg content, 10-20mg vitamin e, 5-10mg beta-carotene,
10mg soybean lecithin, remaining is the mass mixing thing such as olive oil and fish oil.
Described gelatin is animal gelatin.Described titanium dioxide is edible rank titanium dioxide.Described olive oil is extra virgin olive
Olive oil.Described soybean lecithin is the concentrated soybean phospholipid of 60% content of phospholipid.
In described fish oil, dha and epa content is no less than the 50% of fish oil gross mass.
Described have prevention and repair the preparation method that haze damages the nutrition cellulose soft capsules dietary supplement of function, by weight
Amount part meter step is as follows:
(1) glue preparation: prepare the glue for making capsule, glue material therefor is 50 parts of gelatin, glycerol 20-30 part is pure
50 parts of water purification and titanium dioxide 1-2 part;First 1-2 part titanium dioxide is mixed with 10 parts of glycerol, grind 25-35min and be obtained to mix and hang
Supernatant liquid, adds 50 parts of pure water and remaining 10-20 part glycerol, stirs;Add 50 parts of gelatin particles, be heated to 65-70
DEG C, stirring 15-25min is complete to dissolving;Use 100 mesh screen, evacuation, vacuum≤- 0.08mpa under heat-retaining condition, take off
Gas is standby;
(2) preparation of content: be made up of following nutrient by every 500mg content: 5-20 μ g vitamin d, 10-100mg dimension
Raw element e, 5-15mg beta-carotene, 10mg soybean lecithin, remaining is olive oil and/or fish oil;First by fish oil and/or olive
Olive oil is mixed with soybean lecithin, is sufficiently stirred for, and adds vitamin d, vitamin e and beta-carotene, stir in said mixture
Mix 60min fully to dissolve, evacuation.Vacuum≤- 0.08mpa, degassing is stand-by;
(3) preparation of soft capsule: step (1) is prepared gained glue and prepares gained content warp on capsule machine with step (2)
Pelleting makes soft capsule;Wherein glue box temperature 60-65 DEG C, every soft capsule contains 500 ± 50 mg contents;
(4) post processing: the soft capsule that step (3) is pressed into is placed in shape in rotating cage and 3h is dried, 22-25 DEG C of setting temperature is wet
Degree 35%-45%;Subsequently qualitative dried capsule is placed in drying room is dried 36h, 28-31 DEG C of baking temperature, humidity 25%-
35%;Gained capsule is carried out selecting with ball, removes failure, packed with lighttight container, obtain product have prevention and
Repair the nutrition cellulose soft capsules dietary supplement that haze damages function.
Beneficial effects of the present invention: the formula that the present invention provides rationally, rich in multiple high-efficiency antioxidant nutrients, is meeting
Human body daily required on the basis of, fully supplement various have intervene haze damage and anti-oxidation function active substances, can
Effectively prevent and improve the respiratory tract response to oxidative stress of haze pollutant initiation, thus avoiding the reactive oxygen specieses producing further
Cause various inflammation or even cardiovascular disease and cancer with body reaction.
Specific embodiment
The present invention, including but not limited to following Examples are illustrated by following instance.
Embodiment 1
(1) glue preparation: glue material therefor and ratio be, gelatin glycerol pure water titanium dioxide weight ratio is for 50 20 50
1,1 part of titanium dioxide is mixed with 10 parts of glycerol, grinds and mixing suspension is obtained, add 50 parts of pure water and remaining 10 parts of glycerol,
Stir.Add gelatin particle (50 parts), be heated to 65 DEG C.Stir to dissolving completely (about 25min), insulation is filtered, degassing
Standby afterwards;
(2) preparation of content: every 500mg content is made up of following nutrient: 5 μ g vitamin d, 10mg vitamin e, 5mg
Bata-carotene, 10mg soybean lecithin, remaining is olive oil.Collocation method is as follows: olive oil is mixed with soybean lecithin, fills
Divide stirring.Add vitamin d, vitamin e, beta-carotene in said mixture, stirring 60min fully dissolves, and degassing is treated
With;
(3) preparation of soft capsule: glue and content make soft capsule through pelleting on capsule machine.Glue box temperature 60 C, every
Soft capsule content containing 500mg;
(4) post processing: the soft capsule being pressed into is placed in sizing (22 DEG C of temperature, humidity 40% ± 5%) in rotating cage and 3h is dried.It is placed in dry
Dry (28 DEG C of temperature, humidity 30% ± 5%) is dried 36h.Again through selecting ball, remove failure.Wrapped with lighttight container
Dress.
Embodiment 2:
(1) glue preparation: glue material therefor and ratio be, gelatin glycerol pure water titanium dioxide weight ratio is for 50 20 50
1,1 part of titanium dioxide is mixed with 10 parts of glycerol, grinds and mixing suspension is obtained, add 50 parts of pure water and remaining 10 parts of glycerol,
Stir.Add gelatin particle (50 parts), be heated to 70 DEG C.Stir to dissolving completely (about 25min), insulation is filtered, degassing
Standby afterwards.
(2) preparation of content: every 500mg content is made up of following nutrient: 10 μ g vitamin d, 20mg vitamin
E, 10mg bata-carotene, 10mg soybean lecithin, remaining is olive oil.Collocation method is as follows: by olive oil and soybean lecithin
Mixing, is sufficiently stirred for.Add vitamin d, vitamin e, beta-carotene in said mixture, stirring 60min fully dissolves,
Degassing is stand-by.
(3) preparation of soft capsule: glue and content make soft capsule through pelleting on capsule machine.Glue box temperature 60-65
DEG C, every soft capsule content containing 500mg.
(4) post processing: the soft capsule being pressed into is placed in sizing (25 DEG C of temperature, humidity 40% ± 5%) in rotating cage and 3h is dried.
It is placed in drying room (31 DEG C of temperature, humidity 30% ± 5%) and 36h is dried.Again through selecting ball, remove failure.Use lighttight container
Packed.
Embodiment 3
(1) glue preparation: glue material therefor and ratio are that gelatin glycerol pure water titanium dioxide mass ratio is 50 20 50
1,1 part of titanium dioxide is mixed with 10 parts of glycerol, grinds and mixing suspension is obtained, add pure water and remaining 10 parts of glycerol, stirring
Uniformly.Add gelatin particle (50 parts), be heated to 68 DEG C.Stir to dissolving completely (about 25min), insulation is filtered, deaerate standby
With.
(2) preparation of content: every 500mg content is made up of following nutrient: 5 μ g vitamin d, 10mg vitamin
E, 5mg bata-carotene, 10mg soybean lecithin, remaining is fish oil.Collocation method is as follows: fish oil mixed with soybean lecithin,
It is sufficiently stirred for.Add vitamin d, vitamin e, beta-carotene in said mixture, stirring 60min fully dissolves, and degassing is treated
With.
(3) preparation of soft capsule: glue and content make soft capsule through pelleting on capsule machine.Glue box temperature 60-65
DEG C, every soft capsule content containing 500mg.
(4) post processing: the soft capsule being pressed into is placed in sizing (23 DEG C of temperature, humidity 40% ± 5%) in rotating cage and 3h is dried.Put
36h is dried in drying room (30 DEG C of temperature, humidity 30% ± 5%).Again through selecting ball, remove failure.Entered with lighttight container
Row packaging.
Embodiment 4
(1) glue preparation: glue material therefor and ratio are that gelatin glycerol pure water titanium dioxide mass ratio is 50 20 50
1,1 part of titanium dioxide is mixed with 10 parts of glycerol, grinds and mixing suspension is obtained, add pure water and remaining 10 parts of glycerol, stirring
Uniformly.Add gelatin particle (50 parts), be heated to 66 DEG C.Stir to dissolving completely (about 25min), insulation is filtered, deaerate standby
With.
(2) preparation of content: every 500mg content is made up of following nutrient: 10 μ g vitamin d, 20mg vitamin
E, 10mg bata-carotene, 10mg soybean lecithin, remaining is fish oil.Collocation method is as follows: fish oil is mixed with soybean lecithin
Close, be sufficiently stirred for.Add vitamin d, vitamin e, beta-carotene in said mixture, stirring 60min fully dissolves, and takes off
Gas is stand-by.
(3) preparation of soft capsule: glue and content make soft capsule through pelleting on capsule machine.63 DEG C of glue box temperature,
Every soft capsule content containing 500mg.
(4) post processing: the soft capsule being pressed into is placed in sizing (24 DEG C of temperature, humidity 40% ± 5%) in rotating cage and 3h is dried.Put
36h is dried in drying room (31 DEG C of temperature, humidity 30% ± 5%).Again through selecting ball, remove failure.Entered with lighttight container
Row packaging.
Embodiment 5:
(1) glue preparation: glue material therefor and ratio are that gelatin glycerol pure water titanium dioxide mass ratio is 50 20 50
2,2 parts of titanium dioxides are mixed with 10 parts of glycerol, grinds and mixing suspension is obtained, add pure water and remaining 10 parts of glycerol, stirring
Uniformly.Add gelatin particle (50 parts), be heated to 65 DEG C.Stir to dissolving completely (about 25min), insulation is filtered, deaerate standby
With.
(2) preparation of content: every 500mg content is made up of following nutrient: 10 μ g vitamin d, 20mg vitamin
E, 10mg bata-carotene, 10mg soybean lecithin, remaining is the mass mixing thing such as olive oil and fish oil.Collocation method is as follows: will
Fish oil and olive oil are mixed with soybean lecithin, are sufficiently stirred for.Vitamin d, vitamin e, β-recklessly is added in said mixture
Radix Raphani element, stirring 60min fully dissolves, and degassing is stand-by.
(3) preparation of soft capsule: glue and content make soft capsule through pelleting on capsule machine.Glue box temperature 60-65
DEG C, every soft capsule content containing 500mg.
(4) post processing: the soft capsule being pressed into is placed in sizing (25 DEG C of temperature, humidity 40% ± 5%) in rotating cage and 3h is dried.Put
36h is dried in drying room (28 DEG C of temperature, humidity 30% ± 5%).Again through selecting ball, remove failure.Entered with lighttight container
Row packaging.
Claims (9)
1. a kind of have prevention and repair haze damage function nutrition cellulose soft capsules dietary supplement it is characterised in that: include
Capsule and be included in the content in capsule;Described capsule raw material is glue, consists of gelatin glycerol pure water titanium white silty
Amount ratio is 50 20-30 50 1-2;In described content, in every 500mg content, contain 5-20 μ g vitamin d, 10-100mg
Vitamin e, 5-15mg beta-carotene, 10mg soybean lecithin, remaining is olive oil and/or fish oil;Interior in every capsule
Tolerant is 500 ± 50mg.
2. there is prevention as claimed in claim 1 and repair the nutrition cellulose soft capsules dietary supplement that haze damages function, it is special
Levy and be: containing 5-10 μ g vitamin d in described every 500mg content, 10-20mg vitamin e, 5-10mg beta-carotene,
10mg soybean lecithin, remaining is olive oil or fish oil.
3. there is prevention as claimed in claim 1 and repair the nutrition cellulose soft capsules dietary supplement that haze damages function, it is special
Levy and be: containing 5-10 μ g vitamin d in described every 500mg content, 10-20mg vitamin e, 5-10mg beta-carotene,
10mg soybean lecithin, remaining is the mass mixing thing such as olive oil and fish oil.
4. there is prevention as claimed in claim 1 and repair the nutrition cellulose soft capsules dietary supplement that haze damages function, it is special
Levy and be: described gelatin is animal gelatin.
5. there is prevention as claimed in claim 1 and repair the nutrition cellulose soft capsules dietary supplement that haze damages function, it is special
Levy and be: described titanium dioxide is edible rank titanium dioxide.
6. there is prevention as claimed in claim 1 and repair the nutrition cellulose soft capsules dietary supplement that haze damages function, it is special
Levy and be: described olive oil is Extra Virgin.
7. there is prevention as claimed in claim 1 and repair the nutrition cellulose soft capsules dietary supplement that haze damages function, it is special
Levy and be: described soybean lecithin is the concentrated soybean phospholipid of 60% content of phospholipid.
8. there is prevention as claimed in claim 1 and repair the nutrition cellulose soft capsules dietary supplement that haze damages function, it is special
Levy and be: in described fish oil, dha and epa content is no less than the 50% of fish oil gross mass.
9. there is described in claim 1 prevention and repair the preparation side that haze damages the nutrition cellulose soft capsules dietary supplement of function
Method is it is characterised in that step by weight is as follows:
(1) glue preparation: prepare the glue for making capsule, glue material therefor is 50 parts of gelatin, glycerol 20-30 part is pure
50 parts of water purification and titanium dioxide 1-2 part;First 1-2 part titanium dioxide is mixed with 10 parts of glycerol, grind 25-35min and be obtained to mix and hang
Supernatant liquid, adds 50 parts of pure water and remaining 10-20 part glycerol, stirs;Add 50 parts of gelatin particles, be heated to 65-70
DEG C, stirring 15-25min is complete to dissolving;Use 100 mesh screen, evacuation, vacuum≤- 0.08mpa under heat-retaining condition, take off
Gas is standby;
(2) preparation of content: be made up of following nutrient by every 500mg content: 5-20 μ g vitamin d, 10-100mg dimension
Raw element e, 5-15mg beta-carotene, 10mg soybean lecithin, remaining is olive oil and/or fish oil;First by fish oil and/or olive
Olive oil is mixed with soybean lecithin, is sufficiently stirred for, and adds vitamin d, vitamin e and beta-carotene, stir in said mixture
Mix 60min fully to dissolve, evacuation;Vacuum≤- 0.08mpa, degassing is stand-by;
(3) preparation of soft capsule: step (1) is prepared gained glue and prepares gained content warp on capsule machine with step (2)
Pelleting makes soft capsule;Wherein glue box temperature 60-65 DEG C, every soft capsule content containing 500 ± 50mg;
(4) post processing: the soft capsule that step (3) is pressed into is placed in shape in rotating cage and 3h is dried, 22-25 DEG C of setting temperature is wet
Degree 35%-45%;Subsequently qualitative dried capsule is placed in drying room is dried 36h, 28-31 DEG C of baking temperature, humidity 25%-
35%;Gained capsule is carried out selecting with ball, removes failure, packed with lighttight container, obtain product have prevention and
Repair the nutrition cellulose soft capsules dietary supplement that haze damages function.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610719922.7A CN106360782B (en) | 2016-08-25 | 2016-08-25 | A kind of nutrition cellulose soft capsules dietary supplements for having the function of to prevent and repairing haze damage and preparation method thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610719922.7A CN106360782B (en) | 2016-08-25 | 2016-08-25 | A kind of nutrition cellulose soft capsules dietary supplements for having the function of to prevent and repairing haze damage and preparation method thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
CN106360782A true CN106360782A (en) | 2017-02-01 |
CN106360782B CN106360782B (en) | 2018-07-10 |
Family
ID=57879150
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201610719922.7A Active CN106360782B (en) | 2016-08-25 | 2016-08-25 | A kind of nutrition cellulose soft capsules dietary supplements for having the function of to prevent and repairing haze damage and preparation method thereof |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN106360782B (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107279976A (en) * | 2017-07-01 | 2017-10-24 | 山东健康源生物工程有限公司 | A kind of natural VE adds bata-carotene soft capsule and preparation method thereof |
Citations (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5876709A (en) * | 1997-05-26 | 1999-03-02 | New Vision Co., Ltd. | Ophthalmic composition containing active Vitamin D |
CN1568803A (en) * | 2004-04-30 | 2005-01-26 | 南阳市海达生物技术有限公司 | Food with blood-sugar/blood-fat reducing function and preparation method thereof |
CN1660420A (en) * | 2005-01-06 | 2005-08-31 | 昆明圣火制药有限责任公司 | Compound combination of Chinese traditional medicine in use for lowering viscosity of whole blood, thrombolysis and reducing blood fat |
CN101695377A (en) * | 2009-09-14 | 2010-04-21 | 蔡晓东 | Soya bean lecithin soft capsule |
CN103181565A (en) * | 2013-03-07 | 2013-07-03 | 苟春虎 | PM2.5-preventing capsule for clearing away lung toxicant and protecting lungs |
CN103251060A (en) * | 2013-04-17 | 2013-08-21 | 苟春虎 | Dust-haze prevention lung heat clearing capsule |
CN103893240A (en) * | 2014-04-24 | 2014-07-02 | 山东福田药业有限公司 | Composition for preventing and/or treating respiratory system diseases caused by hazes |
CN104095182A (en) * | 2014-06-16 | 2014-10-15 | 李卫平 | Food with protection effect on lung injury caused by fog and haze |
CN104623170A (en) * | 2015-01-07 | 2015-05-20 | 苟春虎 | Anti-haze lung-protecting buccal tablet |
CN105287430A (en) * | 2015-12-01 | 2016-02-03 | 广州市富诺生物科技有限公司 | Algae oil soft capsule and preparation method thereof |
CN105533505A (en) * | 2016-02-25 | 2016-05-04 | 山东禹王制药有限公司 | Chewing-type compound fish oil soft capsules and preparation method thereof |
CN105595323A (en) * | 2015-12-02 | 2016-05-25 | 北京世纪合辉医药科技股份有限公司 | Phosphatide-unsaturated fatty acid compound health product and preparation method thereof |
-
2016
- 2016-08-25 CN CN201610719922.7A patent/CN106360782B/en active Active
Patent Citations (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5876709A (en) * | 1997-05-26 | 1999-03-02 | New Vision Co., Ltd. | Ophthalmic composition containing active Vitamin D |
CN1568803A (en) * | 2004-04-30 | 2005-01-26 | 南阳市海达生物技术有限公司 | Food with blood-sugar/blood-fat reducing function and preparation method thereof |
CN1660420A (en) * | 2005-01-06 | 2005-08-31 | 昆明圣火制药有限责任公司 | Compound combination of Chinese traditional medicine in use for lowering viscosity of whole blood, thrombolysis and reducing blood fat |
CN101695377A (en) * | 2009-09-14 | 2010-04-21 | 蔡晓东 | Soya bean lecithin soft capsule |
CN103181565A (en) * | 2013-03-07 | 2013-07-03 | 苟春虎 | PM2.5-preventing capsule for clearing away lung toxicant and protecting lungs |
CN103251060A (en) * | 2013-04-17 | 2013-08-21 | 苟春虎 | Dust-haze prevention lung heat clearing capsule |
CN103893240A (en) * | 2014-04-24 | 2014-07-02 | 山东福田药业有限公司 | Composition for preventing and/or treating respiratory system diseases caused by hazes |
CN104095182A (en) * | 2014-06-16 | 2014-10-15 | 李卫平 | Food with protection effect on lung injury caused by fog and haze |
CN104623170A (en) * | 2015-01-07 | 2015-05-20 | 苟春虎 | Anti-haze lung-protecting buccal tablet |
CN105287430A (en) * | 2015-12-01 | 2016-02-03 | 广州市富诺生物科技有限公司 | Algae oil soft capsule and preparation method thereof |
CN105595323A (en) * | 2015-12-02 | 2016-05-25 | 北京世纪合辉医药科技股份有限公司 | Phosphatide-unsaturated fatty acid compound health product and preparation method thereof |
CN105533505A (en) * | 2016-02-25 | 2016-05-04 | 山东禹王制药有限公司 | Chewing-type compound fish oil soft capsules and preparation method thereof |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107279976A (en) * | 2017-07-01 | 2017-10-24 | 山东健康源生物工程有限公司 | A kind of natural VE adds bata-carotene soft capsule and preparation method thereof |
Also Published As
Publication number | Publication date |
---|---|
CN106360782B (en) | 2018-07-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN105613789B (en) | High-fat high-dietary-fiber composite animal and plant powdered oil and fat, and preparation method and application thereof | |
RU2338396C2 (en) | Meat and vegetable chopped dietic enriched semi-finished product | |
CN105104584B (en) | The preparation method of peony seed oil powdered oil containing active peptide | |
CN106616615A (en) | Clinical nutrient formula special for tumor and preparation method of clinical nutrient formula | |
CN107319525A (en) | One kind fat-reducing fat reducing tailored version clinical nutrition formula and preparation method thereof | |
CN108902958A (en) | A kind of astaxanthin soft capsule and preparation method thereof | |
CN107440103A (en) | A kind of respiratory disease tailored version clinical nutrition formula and preparation method thereof | |
WO2017032270A1 (en) | Composition for preventing and/or treating cardiovascular and cerebrovascular diseases | |
CN106858595A (en) | One kind burn tailored version clinical nutrition formula and preparation method thereof | |
CN110074397A (en) | A kind of upgrowth and development of children tailored version clinical nutrition formula and preparation method thereof | |
CN107981339A (en) | Tumour full nutrition formula food | |
CN107440102A (en) | A kind of climacteric women tailored version clinical nutrition formula and preparation method thereof | |
CN105747235A (en) | Diet composition able to improve symptoms of metabolic syndrome | |
CN107441217B (en) | Oral emulsion rich in alpha-linolenic acid and preparation method thereof | |
CN101664180B (en) | Health-care nutritional complexing agent with health effect and preparation method thereof | |
CN109172537B (en) | Preparation method of fish oil soft capsules | |
CN106360782A (en) | Nutrient soft capsule dietary supplement having functions of preventing and repairing haze damage and preparation method thereof | |
CN104920967B (en) | Relieving alcoholism and protecting liver type nutritious supplementary and its preparation method | |
CN103719854A (en) | Selenium-rich soybean phosphatides soft capsule and preparation method thereof | |
CN108260802A (en) | A kind of gerontal patient's tailored version clinical nutrition formula and preparation method thereof | |
CN104351778A (en) | Nutritive composition with function of reducing blood fat, and application of nutritive composition | |
CN107836632A (en) | A kind of konjaku lotus leaf dilated food and preparation method thereof | |
CN106173853A (en) | The alimentation composition of a kind of blood fat reducing and application thereof | |
CN103404875A (en) | Complex ocean special-diet food eaten by patients with cardiovascular disease | |
CN1895235A (en) | Production of tremella-polysaccharose capsules |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
GR01 | Patent grant | ||
GR01 | Patent grant |