CN106359417A - Composition of Zhongshengmycin and pyrimidine nucleoside - Google Patents
Composition of Zhongshengmycin and pyrimidine nucleoside Download PDFInfo
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- CN106359417A CN106359417A CN201610781086.5A CN201610781086A CN106359417A CN 106359417 A CN106359417 A CN 106359417A CN 201610781086 A CN201610781086 A CN 201610781086A CN 106359417 A CN106359417 A CN 106359417A
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- zhongshengmycin
- anthrax
- pyrimidine nucleoside
- anthracnose
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
- A01N47/18—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing a —O—CO—N< group, or a thio analogue thereof, directly attached to a heterocyclic or cycloaliphatic ring
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
- A01N37/50—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids the nitrogen atom being doubly bound to the carbon skeleton
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N57/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
- A01N57/10—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-oxygen bonds or phosphorus-to-sulfur bonds
- A01N57/16—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-oxygen bonds or phosphorus-to-sulfur bonds containing heterocyclic radicals
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Abstract
The invention provides a composition of Zhongshengmycin and pyrimidine nucleoside. The composition is characterized in that the weight ratio of the Zhongshengmycin to the pyrimidine nucleoside is 1:10; the composition also comprises kresoxim methyl, and is prepared from, by weight, 0.1%-2% of the Zhongshengmycin, 1%-20% of the pyrimidine nucleoside, 8%-20% of the kresoxim methyl, 1%-8% of an assistant and 50%-89.9% of carriers. According to the composition, the Zhongshengmycin, the pyrimidine nucleoside and the kresoxim methyl are compounded; as the good synergistic interaction effect exists between the Zhongshengmycin, the pyrimidine nucleoside and the kresoxim methyl, on the premise of the similar effective doses, the control effect achieved by compounding the Zhongshengmycin, the pyrimidine nucleoside and the kresoxim methyl is obviously better than that achieved by compounding any two of the Zhongshengmycin, the pyrimidine nucleoside and the kresoxim methyl and is much better than that of any one of the Zhongshengmycin, the pyrimidine nucleoside and the kresoxim methyl; through a large number of experiments, inventors discover that the dosages of the Zhongshengmycin, the pyrimidine nucleoside and the kresoxim methyl in the compounding process are obviously reduced, the cost is greatly reduced, and the drug resistance of various grating cultures can be reduced.
Description
Technical field
The invention belongs to agriculture field, be related to Fungicidal active compound compositionss, more particularly, to pyrimidine nucleoside and other
The compositionss of Fungicidal active compound and its preparation and application.
Background technology
My department discloses Zhongshengmycin and kresoxim-methyl compound scheme, this skill in Patent No. 201310013976.8 invention
The prevention effect potentiation of art substantially, not only expands fungicidal spectrum, prevention and treatment range substantially expands simultaneously.But Zhongshengmycin and pyrimidine core
Glycosides accounts for 25% in the optimal proportion of compositionss, production cost of a relatively high so that promote on be subject to certain restrictions.Easily
Lead to pathogenic bacteria to this kind or the raw drug resistance of its similar antibacterial or Drug resistance.
In addition a kind of " bactericidal composition containing Rhizoma Polygoni Cuspidati extract " of Application No. 201410317070.x discloses middle life
Rhzomorph and/or pyrimidine nucleoside have Synergistic with containing Rhizoma Polygoni Cuspidati extract is compounding, but do not disclose Zhongshengmycin and pyrimidine nucleoside tool
There is this effect.
Clindamycin Main Ingredients and Appearance is clindamycin phosphate.Chemical structural formula: molecular formula: c18h34cln2o8ps；Warp
Cross many experiments show to improve Zhongshengmycin compounding effect have significant gain effect, that is, effectively improve Zhongshengmycin with
The synergistic function of other Fungicidal active compounds.And high potentiation can be kept in the case of low consumption.Also do not send out both at home and abroad
Existing clindamycin and Zhongshengmycin compounding relevant report.
Goal of the invention
Based on above-mentioned background, the invention provides a kind of prevention effect is more excellent, cost is lower, be difficult to make pathogenic bacteria produce drug resistance or
Drug-fast bactericidal composition.
For achieving the above object, technical solution of the present invention is:
A kind of Zhongshengmycin and the compositionss of pyrimidine nucleoside, described Zhongshengmycin is 1:10 with the part by weight of pyrimidine nucleoside, institute
State compositionss and also include kresoxim-methyl, the weight ratio of each composition of compositionss is: Zhongshengmycin 0.1%-2%, pyrimidine nucleoside 1%-20%, ether
Bacterium ester 8%-20%, auxiliary agent 1%-8%, carrier 50%-89.9%.
Described kresoxim-methyl is in composition weight ratio preferably 13%.
Described compositionss also include clindamycin, and described clindamycin accounts for the weight of compositionss than for 0.03%-1.5%.
Described Zhongshengmycin selects wettable powder, weighs proportioning and carries out precomminution, the acquisition that pulverizes and sieves.
Disinfectant use in agriculture described above is in preventing and treating cucumber anthracnose, cucumber bacterial angular leaf spot, cucumber downy mildew, Fructus Lycopersici esculenti
Bacterial speck, Cucurbita pepo L. soft rot, watermelon anthrax, watermelon blight, Citrullus vulgariss root rot, Fructus Cucurbitae moschatae anthrax, Fructus Benincasae charcoal
Cellulitis disease, Fructus Momordicae charantiae anthrax, Fructus Trichosanthis anguinae anthrax, Fructus Melo anthrax, Cucurbita maxima anthrax, Cucurbita pepo L. anthrax, soft rot of cabbage, Chinese cabbage
Clubroot, celery septoria disease, apple anthracnose, ring rot of apple, citrus anthracnose, citrus scab, citrus bacterial canker disease, Citrus
Shot hole, bitter rot or anthracnose of grape, downy mildew of garpe, grapevine anthracnose, fruit white rot of grape, pear scab, peach brown rot, Fructus Musae tikka
Application in disease, cotton anthracnose, cotton in seedling stage damping-off, Diplodia gossypina.
Described disinfectant use in agriculture is mixed with water and is made into medicine liquid spray.
The water of described disinfectant use in agriculture and 500～2000 times of weight mixes.
The having the beneficial effect that of technique scheme
1st, the present invention is compounded by Zhongshengmycin, pyrimidine nucleoside and kresoxim-methyl, due to having good working in coordination between three
Potentiation, on the premise of effective dose is similar, three compounds had preventing and treating effect and will be substantially better than wherein any two kinds,
Better than wherein any single；Through many experiments, another aspect inventor finds that consumption in compounding for the three is all obviously reduced,
Not only cost substantially reduces, and advantageously reduces the Drug resistance that each castor strain is formed to it.
2nd, the present invention adopts clindamycin as compounding composition therein, substantially increases Zhongshengmycin and other activations
The Synergistic ability of compound, many experiments show that Zhongshengmycin is compounded with 1:10 with kresoxim-methyl, and Zhongshengmycin is with regard to respective combination
The optimal accounting of thing is 2%-3%；And the present invention is on the premise of reaching identical prevention effect, Zhongshengmycin consumption only accounts for compositionss
0.2-0.5%, wherein Zhongshengmycin and copper oxychloride weight is than being still 1:10.
With reference to specific embodiment, the present invention is further illustrated.
Specific embodiment
In order to be better understood from the present invention, to further illustrate with reference to specific embodiment.In following embodiments
1000 times of liquid, 2000 times of liquid and 3000 times of liquid refer to for the wettable powder obtaining to add 1000 times, 2000 times and 3000 times
The liquid being uniformly mixed so as to obtain in the water of weight.
Embodiment 1
Each component is gone out wettable powder: Zhongshengmycin 2%, pyrimidine nucleoside according to following percentage by weight by above-mentioned technique productions
20%th, kresoxim-methyl 20%, clindamycin 1.5%, auxiliary agent 8%, carrier 48.5%；Medicament comparison sets 3, respectively contains middle raw bacterium
Element 2%, pyrimidine nucleoside 20%, auxiliary agent 8%, the medicament comparison 1 of carrier 70%；Containing Zhongshengmycin 2%, kresoxim-methyl 20%, auxiliary agent
8%th, the medicament comparison 2 of carrier 70% and Zhongshengmycin 2%, pyrimidine nucleoside 20%, kresoxim-methyl 20%, auxiliary agent 8%, carrier 50%
Medicament comparison 3.Blank is sprayed for clear water.Warm up in Shandong Shouguang City Ji Tai town winter in July, 2014～2014 year October
Formula booth carries out cucumber anthracnose controlling experiment.1000 times of liquid of this wettable powder, 2000 times of liquid, 3000 times of liquid and medicine are set
Agent comparison 1,2,3 is all with 1000 times of liquid of wettable powder and blank treatment region.Foliar spray sprays 1 time for every 7 days, even spray 4 times.
Plot area 30m2, is repeated 4 times, random district's groups arrangement.Wherein 1000 times of liquid of this wettable powder, 2000 times of liquid and 3000 times
Liquid processes the field control effect to cucumber anthracnose and is respectively 97%, 94% and 86%.And 1 wettable powder is shone to medicament
1000 times of liquid sprayings are 76% to the field control effect of cucumber anthracnose, and medicament compares the 1000 times of liquid sprayings of 2 wettable powder
Field control effect to cucumber anthracnose is 90%, and medicament compares 1000 times of liquid of 3 wettable powder and sprays to cucumber anthracnose
Field control effect be 93%.As can be seen here, Zhongshengmycin, pyrimidine nucleoside, kresoxim-methyl three compound rear preventive effect and are substantially better than
Wherein any two kinds of compounding effect, and add clindamycin on the basis of this three again, then preventive effect is optimum.
Embodiment 2
Each component is gone out wettable powder: Zhongshengmycin 0.1%, pyrimidine core according to following percentage by weight by above-mentioned technique productions
Glycosides 1%, kresoxim-methyl 8%, clindamycin 0.03%, auxiliary agent 6%, carrier 84.87%；Medicament comparison sets 3, respectively Zhongshengmycin
0.1%th, the medicament comparison 1 of pyrimidine nucleoside 1%, auxiliary agent 6%, carrier 92.9%；Containing Zhongshengmycin 0.1%, kresoxim-methyl 8%, auxiliary agent
6%th, the medicament comparison 2 of carrier 85.9% and Zhongshengmycin 0.1%, pyrimidine nucleoside 1%, kresoxim-methyl 8%, auxiliary agent 6%, carrier
84.9% medicament comparison 3.Blank is sprayed for clear water.In in November, 2014～2015 year 2 months in Linzi, Shandong imperial city town
Carry out tomato bacterial speck controlling experiment in winter warm type big shack.Arrange 1000 times of liquid of this wettable powder, 2000 times of liquid,
3000 times of liquid and medicament comparison 1,2,3 are all with 1000 times of liquid of wettable powder and blank treatment region.Foliar spray, every 7
Its spray 1 time, even spray 4 times.Plot area 20m2, it is repeated 4 times, random district's groups arrangement.Wherein 1000 times of liquid of this wettable powder,
700 times of liquid, 3000 times of liquid process the field control effect to tomato bacterial speck and are respectively 88%, 85% and 77%.And
It is 62% to the field control effect of tomato bacterial speck that medicament compares the 1000 times of liquid sprayings of 1 wettable powder, medicament pair
According to the 1000 times of liquid sprayings of 2 wettable powder, the field control effect of tomato bacterial speck is only with 73%, medicament comparison 3 can
The spraying of 1000 times of liquid of WP to the field control effect of tomato bacterial speck be 75% it can be seen that, Zhongshengmycin,
Pyrimidine nucleoside, kresoxim-methyl three compound the compounding effect that rear preventive effect is substantially better than wherein any two kinds, and the basis in this three
On again plus clindamycin, then preventive effect is optimum.
Embodiment 3
Each component is gone out wettable powder: Zhongshengmycin 0.5%, pyrimidine core according to following percentage by weight by above-mentioned technique productions
Glycosides 5%, kresoxim-methyl 10%, clindamycin 0.5%, auxiliary agent 7%, carrier 77%；Medicament comparison sets 3, respectively Zhongshengmycin
0.5%th, the medicament comparison 1 of pyrimidine nucleoside 5 ' %, auxiliary agent 7%, carrier 87.5%；Containing Zhongshengmycin 0.5%, kresoxim-methyl 10%, help
Agent 7%, the medicament comparison 2 of carrier 82.5% and Zhongshengmycin 0.5%, pyrimidine nucleoside 5 ' %, kresoxim-methyl 10%, auxiliary agent 7%, load
The medicament comparison 3 of body 77.5%.Blank is sprayed for clear water.Enter in Yiyuan county in September, 2014～2014 year December
Row apple anthracnose controlling experiment.Arrange 1000 times of liquid of this wettable powder, 2000 times of liquid, 3000 times of liquid and medicament comparison 1,
2nd, 3 all with 2000 times of liquid of wettable powder and blank treatment region.Foliar spray, sprays 1 time, even spray 4 times for every 7 days.Cell face
Long-pending 30m2, it is repeated 4 times, random district's groups arrangement.Wherein 1000 times of liquid of this wettable powder, 2000 times of liquid and 3000 times of liquid are processed
98%, 95% and 89% is respectively to the field control effect of apple anthracnose.And medicament compares 1 wettable powder 2000
The spraying of times liquid is only 65% to the field control effect of apple anthracnose, and it is right that medicament compares the 2000 times of liquid sprayings of 2 wettable powder
The field control effect of apple anthracnose is 78%, and medicament compares 1000 times of liquid of 3 wettable powder and sprays to apple anthracnose
Field control effect be 83% it can be seen that, Zhongshengmycin, pyrimidine nucleoside, kresoxim-methyl three compound after preventive effect be substantially better than it
In any two kinds of compounding effect, and on the basis of this three again plus clindamycin, then preventive effect is optimum, and embodiment 1 is fitted relatively
When increasing clindamycin consumption, effect is significant improves.
Embodiment 4
Each component is gone out wettable powder: Zhongshengmycin 1%, pyrimidine nucleoside according to following percentage by weight by above-mentioned technique productions
10%th, kresoxim-methyl 12%, clindamycin 0.8%, auxiliary agent 8%, carrier 68.2%；Medicament comparison sets 3, respectively Zhongshengmycin
1%th, the medicament comparison 1 of pyrimidine nucleoside 10%, auxiliary agent 8%, carrier 81%；Containing Zhongshengmycin 1%, kresoxim-methyl 12%, auxiliary agent 8%,
The medicament comparison 2 of carrier 79% and Zhongshengmycin 1%, pyrimidine nucleoside 10%, kresoxim-methyl 12%, auxiliary agent 8%, the medicine of carrier 69%
Agent comparison 3.Blank is sprayed for clear water.Carry out ring rot of apple in September, 2014～2014 year December in Yiyuan county
Controlling experiment.1000 times of liquid of this wettable powder, 2000 times of liquid, 3000 times of liquid and medicament comparison 1,2,3 are set all with wettable
Property 2000 times of liquid of powder and blank treatment region.Foliar spray, sprays 1 time, even spray 4 times for every 7 days.Plot area 50m2, repeat 3
Secondary, random district's groups arrangement.Wherein 1000 times of liquid of this wettable powder, 2000 times of liquid and 3000 times of liquid are processed to ring rot of apple
Field control effect be respectively 95%, 92% and 84%.And medicament compares 2000 times of liquid of 1 wettable powder and sprays to Fructus Mali pumilae
The field control effect of ring spot is 68%, and medicament compares the field to ring rot of apple for the 2000 times of liquid sprayings of 2 wettable powder
Prevention effect is only 73%, and medicament compares 2000 times of liquid of 3 wettable powder and only sprays the field control effect to Citrullus vulgariss water flesh melon
For 83% it can be seen that, Zhongshengmycin, pyrimidine nucleoside, kresoxim-methyl three compound after preventive effect be substantially better than wherein any two kinds
Compounding effect, and add clindamycin on the basis of this three again, then preventive effect is optimum.
Embodiment 5
Each component is gone out wettable powder: Zhongshengmycin 0.4%, pyrimidine core according to following percentage by weight by above-mentioned technique productions
Glycosides 4%, kresoxim-methyl 18%, clindamycin 0.6%, auxiliary agent 8%, carrier 69%；Medicament comparison sets 3, respectively Zhongshengmycin
0.4%th, the medicament comparison 1 of pyrimidine nucleoside 4%, auxiliary agent 8%, carrier 85.6%；Containing Zhongshengmycin 0.4%, kresoxim-methyl 18%, help
Agent 8%, the medicament comparison 2 of carrier 73.6% and Zhongshengmycin 0.4%, pyrimidine nucleoside 4%, kresoxim-methyl 18%, auxiliary agent 8%, carrier
69.6% medicament comparison 3.Blank is sprayed for clear water.Carry out west in October, 2014～2015 year January Shandong Changyue County
The controlling experiment of melon anthrax.Arrange 1000 times of liquid of this wettable powder, 2000 times of liquid, 3000 times of liquid and medicament comparison 1,2,
3 all with 2000 times of liquid of wettable powder and blank treatment region.Aerosol apparatus foliar spray, sprays 1 time, even spray 3 times for every 10 days.Little
Area is test individual plant, is repeated 4 times, random district's groups arrangement.Wherein 1000 times of liquid of this wettable powder, 2000 times of liquid and 3000 times
Liquid processes the field control effect to watermelon anthrax and is respectively 94%, 91% and 82%.And medicament compares 1 wettable powder
2000 times of liquid sprayings are 62% to the field control effect of citrus bacterial canker disease, and medicament compares the 2000 times of liquid sprayings of 2 wettable powder
70% is only to the field control effect of watermelon anthrax, medicament compares 2000 times of liquid of 3 wettable powder and sprays to Citrullus vulgariss anthrax
Disease field control effect be only 77% it can be seen that, Zhongshengmycin, pyrimidine nucleoside, kresoxim-methyl three compound after preventive effect obvious
Compounding effect better than wherein any two kinds, and add clindamycin on the basis of this three again, then preventive effect is optimum.
Embodiment 6
Each component is gone out wettable powder: Zhongshengmycin 1.2%, pyrimidine core according to following percentage by weight by above-mentioned technique productions
Glycosides 12%, kresoxim-methyl 17%, clindamycin 0.08%, auxiliary agent 5%, carrier 64.72%；Medicament comparison sets 3, respectively middle raw bacterium
Element 1.2%, pyrimidine nucleoside 12%, auxiliary agent 5%, the medicament comparison 1 of carrier 81.8%；Containing Zhongshengmycin 1.2%, kresoxim-methyl 17%,
Auxiliary agent 5%, the medicament comparison 2 and Zhongshengmycin 1.2% of carrier 76.8%, pyrimidine nucleoside 12%, kresoxim-methyl 17%, auxiliary agent 5%,
The medicament comparison 3 of carrier 64.8%.Blank is sprayed for clear water.In in April, 2015～2015 year November in Yiyuan county
Carry out the controlling experiment of downy mildew of garpe.Grape variety is U.S.'s HONGTI.Arrange 1000 times of liquid of this wettable powder, 2000 times
Liquid, 3000 times of liquid and medicament comparison 1,2,3 are all with 2000 times of liquid of wettable powder and blank treatment region.Spray 1 in every 10 days
Secondary, even spray 3 times.Cell is test individual plant, is repeated 4 times, random district's groups arrangement.Wherein 1000 times of liquid of this wettable powder, 2000
Times liquid and 3000 times of liquid process the field control effect to downy mildew of garpe and are respectively 95%, 92% and 87%.And medicament comparison 1
700 times of liquid sprayings of wettable powder are 68% to the field control effect of downy mildew of garpe, and medicament compares 2 wettable powders 700
The spraying of times liquid is only 73% to the field control effect of downy mildew of garpe, and medicament compares 700 times of liquid of 3 wettable powder and sprays to Portugal
The field control effect of grape downy mildew be only 80% it can be seen that, Zhongshengmycin, pyrimidine nucleoside, kresoxim-methyl three compound rear defence
Effect is substantially better than wherein any two kinds of compounding effect, and adds clindamycin on the basis of this three again, then preventive effect is optimum.
The microbicide compositions of the present invention, in addition to preparing the wettable powder in above-described embodiment, also can make other agent
Type, such as liquid preparation.As wettable powder, after making other dosage forms, the present invention compound not only can potentiation, and permissible
Expanding prevention is composed.
Show through test of many times:
After Zhongshengmycin, pyrimidine nucleoside and kresoxim-methyl compound by a certain percentage, obvious potentiation can be produced.Zhongshengmycin and
After pyrimidine nucleoside compounds according to the ratio of 1:10, apply general method to carry out indoor bioassay, cucumber anthracnose is total to
Malicious coefficient is 168.15, and the preparation method pressing the present invention compounds co-toxicity coefficient lifting more than 17%, overall preventive effect lifting 17% with
On；If combining micro clindamycin, above-mentioned two index then all can lift more than 20%, and potentiation is notable！Said components of the present invention
Synergy, makes the bactericidal activity of the present invention significantly improve.
After Zhongshengmycin, pyrimidine nucleoside and kresoxim-methyl compound, to cucumber anthracnose, cucumber bacterial angular leaf spot, Cucumis satiuus L.
Mildew, tomato bacterial speck, Cucurbita pepo L. soft rot, watermelon anthrax, watermelon blight, Citrullus vulgariss root rot, Fructus Cucurbitae moschatae anthrax
Disease, Fructus Benincasae anthrax, Fructus Momordicae charantiae anthrax, Fructus Trichosanthis anguinae anthrax, Fructus Melo anthrax, Cucurbita maxima anthrax, Cucurbita pepo L. anthrax, Chinese cabbage are soft
Maize ear rot, cabbage clubroot, the late blight of potato, celery septoria disease, apple anthracnose, ring rot of apple, citrus anthracnose, Citrus
Shot hole, citrus bacterial canker disease, citrus scab, bitter rot or anthracnose of grape, downy mildew of garpe, grapevine anthracnose, fruit white rot of grape, pears are black
Star disease, peach brown rot, sigatoka, cotton anthracnose, cotton in seedling stage damping-off, the prevention effect of Diplodia gossypina are respectively provided with
Significantly improve.
Claims (10)
1. a kind of Zhongshengmycin and pyrimidine nucleoside compositionss it is characterised in that: the weight of described Zhongshengmycin and pyrimidine nucleoside
Ratio is 1:10, and described compositionss also include kresoxim-methyl, and the weight ratio of each composition of compositionss is: Zhongshengmycin 0.1%-2%, pyrimidine
Nucleoside 1%-20%, kresoxim-methyl 8%-20%, auxiliary agent 1%-8%, carrier 50%-89.9%.
2. as claimed in claim 1 a kind of Zhongshengmycin and pyrimidine nucleoside compositionss it is characterised in that: described kresoxim-methyl exists
Composition weight ratio preferably 13%.
3. as claimed in claim 1 a kind of Zhongshengmycin and pyrimidine nucleoside compositionss it is characterised in that: described compositionss are also
Including clindamycin, described clindamycin accounts for the weight of compositionss than for 0.03%-1.5%.
4. as claimed in claim 1 a kind of Zhongshengmycin and pyrimidine nucleoside compositionss it is characterised in that: described Zhongshengmycin
From wettable powder, weigh proportioning and carry out precomminution, the acquisition that pulverizes and sieves.
5. the disinfectant use in agriculture any one of a kind of claims 1 to 3 is in preventing and treating cucumber anthracnose, Fructus Cucumidis sativi bacillary angle speckle
Disease, cucumber downy mildew, tomato bacterial speck, Cucurbita pepo L. soft rot, watermelon anthrax, watermelon blight, Citrullus vulgariss root rot,
Fructus Cucurbitae moschatae anthrax, Fructus Benincasae anthrax, Fructus Momordicae charantiae anthrax, Fructus Trichosanthis anguinae anthrax, Fructus Melo anthrax, Cucurbita maxima anthrax, Cucurbita pepo L. anthrax
Disease, soft rot of cabbage, cabbage clubroot, celery septoria disease, apple anthracnose, ring rot of apple, citrus anthracnose, Citrus scab
The black star of disease, citrus bacterial canker disease, citrus scab, bitter rot or anthracnose of grape, downy mildew of garpe, grapevine anthracnose, fruit white rot of grape, pears
Application in disease, peach brown rot, sigatoka, cotton anthracnose, cotton in seedling stage damping-off, Diplodia gossypina.
6. the disinfectant use in agriculture described in a kind of claim 5 is in preventing and treating cucumber anthracnose, cucumber bacterial angular leaf spot, Fructus Cucumidis sativi downy mildew
Disease, tomato bacterial speck, Cucurbita pepo L. soft rot, watermelon anthrax, watermelon blight, Citrullus vulgariss root rot, Fructus Cucurbitae moschatae anthrax,
Fructus Benincasae anthrax, Fructus Momordicae charantiae anthrax, Fructus Trichosanthis anguinae anthrax, Fructus Melo anthrax, Cucurbita maxima anthrax, Cucurbita pepo L. anthrax, the soft corruption of Chinese cabbage
Disease, cabbage clubroot, celery septoria disease, apple anthracnose, ring rot of apple, citrus anthracnose, citrus scab, c itrus canker
Disease, citrus scab, bitter rot or anthracnose of grape, downy mildew of garpe, grapevine anthracnose, fruit white rot of grape, pear scab, peach brown rot,
Application in sigatoka, cotton anthracnose, cotton in seedling stage damping-off, Diplodia gossypina.
7. application according to claim 6 it is characterised in that: described disinfectant use in agriculture and water mix and are made into medicine liquid spray.
8. application according to claim 7 it is characterised in that: described disinfectant use in agriculture and water mix and are made into medicine liquid spray.
9. according to claim 8 application it is characterised in that: the water of described disinfectant use in agriculture and 500～2000 times of weight
Mix.
10. according to claim 8 application it is characterised in that: the water of described disinfectant use in agriculture and 500～2000 times of weight
Mix.
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| CN201610781086.5A CN106359417A (en) | 2016-08-31 | 2016-08-31 | Composition of Zhongshengmycin and pyrimidine nucleoside |
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| CN201610781086.5A CN106359417A (en) | 2016-08-31 | 2016-08-31 | Composition of Zhongshengmycin and pyrimidine nucleoside |
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| CN102669133A (en) * | 2012-05-21 | 2012-09-19 | 四川农业大学 | Seed coating agent for preventing ginger wilt |
| CN103355352A (en) * | 2012-04-07 | 2013-10-23 | 陕西韦尔奇作物保护有限公司 | Pyrimidine nucleoside antibiotic/methoxy acrylate bactericidal composition |
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| US4655815A (en) * | 1985-03-27 | 1987-04-07 | Calgon Corporation | Admixtures of 2-bromo-2-bromomethylglutaronitrile and a formaldehyde donor |
| CN1957700A (en) * | 2006-10-31 | 2007-05-09 | 陕西绿盾生物制品有限责任公司 | Wettable powder of high containing antibiotic in pyrimidine nucleoside class, and preparation method |
| CN101647453A (en) * | 2009-07-15 | 2010-02-17 | 深圳诺普信农化股份有限公司 | Synergy combination containing kresoxim-methyl |
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