CN106349347A - 一种小分子多肽、及其编码基因和应用 - Google Patents
一种小分子多肽、及其编码基因和应用 Download PDFInfo
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- CN106349347A CN106349347A CN201610938432.6A CN201610938432A CN106349347A CN 106349347 A CN106349347 A CN 106349347A CN 201610938432 A CN201610938432 A CN 201610938432A CN 106349347 A CN106349347 A CN 106349347A
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- micromolecule polypeptide
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- 229920005990 polystyrene resin Polymers 0.000 description 1
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- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
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- NCEXYHBECQHGNR-QZQOTICOSA-N sulfasalazine Chemical compound C1=C(O)C(C(=O)O)=CC(\N=N\C=2C=CC(=CC=2)S(=O)(=O)NC=2N=CC=CC=2)=C1 NCEXYHBECQHGNR-QZQOTICOSA-N 0.000 description 1
- 229960001940 sulfasalazine Drugs 0.000 description 1
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- WGTODYJZXSJIAG-UHFFFAOYSA-N tetramethylrhodamine chloride Chemical compound [Cl-].C=12C=CC(N(C)C)=CC2=[O+]C2=CC(N(C)C)=CC=C2C=1C1=CC=CC=C1C(O)=O WGTODYJZXSJIAG-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
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Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030175971A1 (en) * | 2001-12-28 | 2003-09-18 | Geoffrey Lindeman | Differentiation and/or proliferation modulating agents and uses therefor |
CN103397103A (zh) * | 2013-08-26 | 2013-11-20 | 中国人民解放军第三军医大学第三附属医院 | 一种检测socs家族基因标签单核甘酸多态性位点的方法及试剂盒 |
WO2015112904A1 (en) * | 2014-01-24 | 2015-07-30 | University Of Florida Research Foundation, Inc. | Socs mimetics for the treatment of diseases |
WO2015181427A1 (es) * | 2014-05-28 | 2015-12-03 | Fundació Hospital Universitari Vall D'hebron - Institut De Recerca | Péptido derivado de socs1 para su uso en complicaciones crónicas de la diabetes |
-
2016
- 2016-10-25 CN CN201610938432.6A patent/CN106349347B/zh active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030175971A1 (en) * | 2001-12-28 | 2003-09-18 | Geoffrey Lindeman | Differentiation and/or proliferation modulating agents and uses therefor |
CN103397103A (zh) * | 2013-08-26 | 2013-11-20 | 中国人民解放军第三军医大学第三附属医院 | 一种检测socs家族基因标签单核甘酸多态性位点的方法及试剂盒 |
WO2015112904A1 (en) * | 2014-01-24 | 2015-07-30 | University Of Florida Research Foundation, Inc. | Socs mimetics for the treatment of diseases |
WO2015181427A1 (es) * | 2014-05-28 | 2015-12-03 | Fundació Hospital Universitari Vall D'hebron - Institut De Recerca | Péptido derivado de socs1 para su uso en complicaciones crónicas de la diabetes |
Non-Patent Citations (6)
Title |
---|
CHRISTIAN KOELSCHE 等: "Structural and functional analysis of a nuclear localization signal in SOCS1", 《MOLECULAR IMMUNOLOGY》 * |
FABRIZIO GIORDANETTO 等: "A three-dimensional model of Suppressor Of Cytokine Signalling 1(SOCS-1)", 《PROTEIN ENGINEERING》 * |
XIANWEN CHEN 等: "On-Bead Screening of Combinatorial Libraries: Reduction of Nonspecific Binding by Decreasing Surface Ligand Density", 《J COMB CHEM.》 * |
崔强 等: "一种新的疾病治疗候选基因:SOCS-1", 《生命科学》 * |
牛宏垚 等: "STAT蛋白在炎症性肠病发病机制中的作用", 《国际消化病杂志》 * |
赵晓彪 等: "SOCS1与肿瘤发生、发展和治疗的研究进展", 《现代生物医学进展》 * |
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