CN106349130B - 一种新的氟苯尼考的合成方法 - Google Patents
一种新的氟苯尼考的合成方法 Download PDFInfo
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- CN106349130B CN106349130B CN201610721774.2A CN201610721774A CN106349130B CN 106349130 B CN106349130 B CN 106349130B CN 201610721774 A CN201610721774 A CN 201610721774A CN 106349130 B CN106349130 B CN 106349130B
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- Prior art keywords
- florfenicol
- synthetic method
- alcohol
- tetrahydrochysene
- fluoro
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C315/00—Preparation of sulfones; Preparation of sulfoxides
- C07C315/04—Preparation of sulfones; Preparation of sulfoxides by reactions not involving the formation of sulfone or sulfoxide groups
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
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CN201610721774.2A CN106349130B (zh) | 2016-08-25 | 2016-08-25 | 一种新的氟苯尼考的合成方法 |
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CN201610721774.2A CN106349130B (zh) | 2016-08-25 | 2016-08-25 | 一种新的氟苯尼考的合成方法 |
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CN106349130A CN106349130A (zh) | 2017-01-25 |
CN106349130B true CN106349130B (zh) | 2018-01-23 |
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Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
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BR112020008834A2 (pt) | 2017-11-02 | 2020-12-22 | Calico Life Sciences Llc | Moduladores da via de estresse integrada |
UY37956A (es) * | 2017-11-02 | 2019-05-31 | Abbvie Inc | Moduladores de la vía de estrés integrada |
TWI832295B (zh) | 2018-10-11 | 2024-02-11 | 美商嘉來克生命科學有限責任公司 | 整合應激路徑之前藥調節劑 |
CN110256371A (zh) * | 2019-07-09 | 2019-09-20 | 京山瑞生制药有限公司 | 一种新的氟苯尼考关键中间体的制备方法 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5352832A (en) * | 1992-12-18 | 1994-10-04 | Schering Corporation | Asymmetric process for preparing florfenicol, thiamphenicol chloramphenicol and oxazoline intermediates |
CN1743308A (zh) * | 2005-08-12 | 2006-03-08 | 中国科学院上海有机化学研究所 | 甲砜霉素和氟苯尼考的新合成方法及其关键中间体 |
CN101941927A (zh) * | 2010-09-28 | 2011-01-12 | 湖北美天生物科技有限公司 | 氟苯尼考中间体(1r,2r)-2-氨基-1–(4-(甲砜基)苯基)-1,3-丙二醇的合成方法 |
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2016
- 2016-08-25 CN CN201610721774.2A patent/CN106349130B/zh active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5352832A (en) * | 1992-12-18 | 1994-10-04 | Schering Corporation | Asymmetric process for preparing florfenicol, thiamphenicol chloramphenicol and oxazoline intermediates |
CN1743308A (zh) * | 2005-08-12 | 2006-03-08 | 中国科学院上海有机化学研究所 | 甲砜霉素和氟苯尼考的新合成方法及其关键中间体 |
CN101941927A (zh) * | 2010-09-28 | 2011-01-12 | 湖北美天生物科技有限公司 | 氟苯尼考中间体(1r,2r)-2-氨基-1–(4-(甲砜基)苯基)-1,3-丙二醇的合成方法 |
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CN106349130A (zh) | 2017-01-25 |
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Denomination of invention: A new synthetic method of Florfenicol Effective date of registration: 20220629 Granted publication date: 20180123 Pledgee: China Everbright Bank Co.,Ltd. Weifang branch Pledgor: Weifang Dayoo Biochemical Co.,Ltd. Registration number: Y2022980009530 |
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Date of cancellation: 20230628 Granted publication date: 20180123 Pledgee: China Everbright Bank Co.,Ltd. Weifang branch Pledgor: Weifang Dayoo Biochemical Co.,Ltd. Registration number: Y2022980009530 |
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Denomination of invention: A New Synthesis Method of Flufenicol Effective date of registration: 20230629 Granted publication date: 20180123 Pledgee: China Everbright Bank Co.,Ltd. Weifang branch Pledgor: Weifang Dayoo Biochemical Co.,Ltd. Registration number: Y2023980046826 |
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