CN106334107A - Traditional Chinese medicine eye drops and preparation method thereof - Google Patents

Traditional Chinese medicine eye drops and preparation method thereof Download PDF

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CN106334107A
CN106334107A CN201610753786.3A CN201610753786A CN106334107A CN 106334107 A CN106334107 A CN 106334107A CN 201610753786 A CN201610753786 A CN 201610753786A CN 106334107 A CN106334107 A CN 106334107A
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chinese medicine
traditional chinese
radix
semen cassiae
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刘丰文
杜浩儒
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    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
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    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
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    • A61K36/75Rutaceae (Rue family)
    • A61K36/756Phellodendron, e.g. corktree
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    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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    • A61K2236/55Liquid-liquid separation; Phase separation

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Abstract

The invention discloses traditional Chinese medicine eye drops. The eye drops are prepared from, by weight, 40-60 parts of mulberry bark, 1-5 parts of coptidis rhizome, 1-3 parts of cortex phellodendri, 1-4 parts of radix scutellariae, 2-4 parts of borneol, 1.5-3.5 parts of licorice root, 6-12 parts of semen cassiae, 5-9 parts of bamboo leaves, 3-6 parts of honeysuckle, 3-9 parts of fructus lycii and 2-6 parts of salviae miltiorrhizae. Meanwhile, the invention discloses a preparation method of the eye drops. The eye drops are prepared through compatibility of the raw materials, have the effects of inducing diuresis for removing edema, clearing heat and toxin, stopping pain and purging fire and removing liver fire for improving eyesight, have a good treatment effect on various inflammations of eyes, blood capillary blockage, eye muscle atrophy, fatigue, nerve palsies and the like, can effectively relieve dry eyes and light discomfort, can have eye moistening and eyesight improving functions, and are worthy of wide application and popularization.

Description

A kind of Traditional Chinese medicine eye drop and preparation method thereof
Technical field
The invention belongs to collyrium technical field is and in particular to a kind of Traditional Chinese medicine eye drop and preparation method thereof.
Background technology
Collyrium is one of the most frequently used pharmaceutical dosage form of ophthalmic diseasess, and for many oculopathy, collyrium has direct, quick Therapeutical effect.For the patient having suffered from oculopathy, on the one hand need to correct it with eye custom, be on the other hand also required to certain The auxiliary treatment of medicine.Traditional Chinese Medicine uses Chinese medicine based on decoction, separately has pill, powder, extract and pellet preparation, for thousands of years for people's civil defence disease Cure the disease;The external eye dripping medicine for the treatment of oculopathy mostly is its composition of western medicine component at present has numerous species according to the difference of effect, for example Steroid, antibiotic, antihistaminic, beta-blocker, non-steroidal anti-inflammatory analgesic etc..General collyrium is in order to preserve for a long time And with the addition of micro preservative, human body will not be impacted under normal use.If but life-time service contains preservative Collyrium, is easier to cause cornea injured, the symptom such as one's eyes became bloodshot, photophobia.
Content of the invention
It is an object of the invention to provide a kind of Traditional Chinese medicine eye drop, provide the preparation method of this collyrium simultaneously.
For achieving the above object, the present invention adopts the following technical scheme that
A kind of Traditional Chinese medicine eye drop, is made up of the raw material of following weight portion: 40~60 parts of Cortex Mori, 1~5 part of Rhizoma Coptidis, Cortex Phellodendri 1~ 3 parts, 1~4 part of Radix Scutellariae, 2~4 parts of Borneolum Syntheticum, 1.5~3.5 parts of Radix Glycyrrhizae, 6~12 parts of Semen Cassiae, 5~9 parts of Folium Bambusae, Flos Lonicerae 3~6 Part, 3~9 parts of Fructus Lycii, 2~6 parts of Radix Salviae Miltiorrhizae.
Preferably, a kind of Traditional Chinese medicine eye drop, is made up of the raw material of following weight portion: 48~52 parts of Cortex Mori, 2~4 parts of Rhizoma Coptidis, 1.5~2.5 parts of Cortex Phellodendri, 1.5~3 parts of Radix Scutellariae, 2.5~3.5 parts of Borneolum Syntheticum, 1.7~2.3 parts of Radix Glycyrrhizae, 8~10 parts of Semen Cassiae, Folium Bambusae 6 ~8 parts, 4~5 parts of Flos Lonicerae, 6~7 parts of Fructus Lycii, 3~5 parts of Radix Salviae Miltiorrhizae.
It is further preferred that a kind of Traditional Chinese medicine eye drop, be made up of the raw material of following weight portion: 50 parts of Cortex Mori, 3 parts of Rhizoma Coptidis, 2 parts of Cortex Phellodendri, 2 parts of Radix Scutellariae, 3 parts of Borneolum Syntheticum, 2 parts of Radix Glycyrrhizae, 9 parts of Semen Cassiae, 7 parts of Folium Bambusae, 4 parts of Flos Lonicerae, 6.5 parts of Fructus Lycii, Radix Salviae Miltiorrhizae 4 Part.
The preparation method of above-mentioned Traditional Chinese medicine eye drop, comprises the following steps: (1) by Cortex Mori, Rhizoma Coptidis, Cortex Phellodendri, Radix Scutellariae, Radix Glycyrrhizae, Obtain mixture after Semen Cassiae, Folium Bambusae, Flos Lonicerae, Fructus Lycii, Radix Salviae Miltiorrhizae co-grinding are uniform, add the water of 6-8 times of mixture quality, After boiling 2-5h, filter to get filtrate;
(2) filtrate heating is concentrated to give concentrated solution, the volume of concentrated solution is the 1/3~1/2 of filtrate, and concentrated solution is in 60-80 DEG C distilation 1-3 hour must purify liquid, adds Borneolum Syntheticum mix homogeneously in purification liquid.
When Traditional Chinese medicine eye drop of the present invention uses, 2-4 can be dripped as needed every time and drips as drop, daily 1-3 time;? For cleaning eyes, the sense of discomfort of eye can be removed, reaches the purpose of moistening improving eyesight as abluent.Chinese herb medicine eye of the present invention No matter liquid medicine is to use as drop or clean eyes as abluent, all obstructed to the various inflammation of eyes, blood capillary, Ocular muscle dystrophy, fatigue, nerve numb etc. have good therapeutic effect, can effectively alleviate that eye is dry and astringent and slight sense of discomfort, with When can play the effect of moistening improving eyesight.
Each raw material medical mechanism of the present invention is:
Cortex Mori sweet in the mouth, slight bitter, return lung, spleen channel, liver heat removing, improving eyesight, inducing diuresis to remove edema, cure mainly: dyspnea and cough due to lung-heat, diseases caused by retention of fluid stops lung, swollen Full dyspnea with rapid respiration, is especially apt to purte the white and relievings asthma and cough, control lung heat cough and asthma, expectorant is thick and yellow.
Rhizoma Coptidis heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomit acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, heart-fire is high Contain, dysphoria and insomnia, blood-head tells nosebleed, conjunctival congestion, toothache, quench one's thirst, carbuncle swells furunculosis;External treatment eczema, eczema, auditory meatus are suppurated.Rhizoma Coptidis (processed with wine) is apt to The clear part of the body cavity above the diaphragm housing the heart and lungs is burning hot.For conjunctival congestion, aphtha.
Cortex Phellodendri bitter in the mouth, cold in nature, return kidney, bladder warp, there is heat clearing and damp drying, purging intense heat, except steaming, effect of detoxification sore treatment, for wet Diarrhea of heat type dysentery, jaundice urine is red, leukorrhagia pudendal pruritus, puckery pain of heat gonorrhea, tinea pedis flaccidity is knitted, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, and eczema is wet Skin ulcer.Stir-baked CORTEX PHELLODENDRI with salt solution nourishing YIN to lower pathogenic fire.For hyperactivity of fire caused by deficiency of YIN, night sweat hectic fever due to YIN-deficiency.
Radix Scutellariae: bitter, cold, return lung, gallbladder, stomach, large intestine channel, heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive, tonifying Qi and lifting yang, benefit Superficies-consolidating, inducing diuresis to remove edema.
Borneolum Syntheticum, also known as piece brain, Fructus Citri tangerinae piece, Blumeae preparatum Tabellae, Borneolum Syntheticum, MEIHUA BINGPIAN, Dipterocarpus pilosus, Flos Mume brain, Borneolum Syntheticum brain, Mei Bing Deng, be by Compositae Herba Blumeae Balsamiferae stem and leaf or canella Borneolum Syntheticum Camphor tree branch and leaf through steam distillation and recrystallization and obtain;Acrid in the mouth, hardship, micro- Cold;GUIXIN, liver, lung meridian;Delicate fragrance a surname dissipate, has inducing resuscitation of having one's ideas straightened out, heat-clearing dissipates poison, effect of improving acuity of vision and removing nebula, cures mainly calentura hyperpyrexia god Dusk, apoplexy coma due to blocking of the respiratory system shies epilepsy, summer-heat and damp blinds clear key, larynx numbness is deaf, aphtha tooth swells, sore carbuncle infantile malnutrition due to digestive disturbances or intestinalparasites hemorrhoid, conjunctival congestion and swelling pain, pterygium.
Radix Glycyrrhizae: nature and flavor and return through: sweet, put down.GUIXIN, spleen, lung, stomach.Function with cure mainly: spleen reinforcing stomach function regulating, Yiqi and vein recovery.Spleen Stomach is weak, fatigue and weakness, severe palpitation, irregularly intermittent and regularly intermittent pulse.
Semen Cassiae has the function of liver heat removing and eyesight improving, relieving constipation, and Semen Cassiae contains multivitamin and abundant aminoacid, fat Fat, carbohydrate etc., in recent years its health care be increasingly subject to the attention of people.Semen Cassiae has clearing away liver-fire, wind-damp dispelling, benefit The functions such as kidney improving eyesight, often drink cassia-tora tea, and blood pressure can be made normal, free movement of the bowels, and there is no blurred vision.Clinical trial certificate, drinks Semen Cassiae Sub- tea can with liver heat removing and eyesight improving, prevent blurred vision, lowering blood pressure and blood fat, reduce cholesterol etc., for prevention and treatment of coronary heart disease, high blood Pressure has good curative effect;And Semen Cassiae is rich in vitamin a and zinc, can prevent and treat nyctalopia and avoid zinc deficiency in children.
Folium Bambusae: effect: clearing heat and relieving fidgetness, diuresis of promoting the production of body fluid.Cure mainly: control pyreticosis polydipsia, pediatric epilepsy scared, cough with dyspnea tells nosebleed, flushed complexion is little Just short red, erosion of the oral mucosa tongue boil.Source: Folium Bambusae is the leaf of grass henon bamboo, clearing heat and relieving fidgetness, diuresis of promoting the production of body fluid.Control pyreticosis polydipsia, little Youngster's infantile convulsion, cough with dyspnea tells nosebleed, flushed complexion, oliguria also, erosion of the oral mucosa tongue boil.
Flos Lonicerae is described as the good medicine of heat-clearing and toxic substances removing from ancient times.Its property sweet cold fragrance, clearing away heat with drugs sweet in flavor and cold in nature and do not injure one's stomach, fragrance is thoroughly Reach and can eliminating evil.Flos Lonicerae can dispelling wind-heat, be also apt to removing summer-heat blood poison, for various febrile diseases, such as fever of the body, dermexanthesis, send out speckle, heat The diseases such as skin infection carbuncle, laryngopharynx swelling and pain, equal effect is significant.
Fructus Lycii sweet in the mouth, mild-natured.Tonifying liver, kidney tonifying.Compendium of Material Medica carries: " long term usage heavily fortified point muscles and bones, makes light of one's life by commiting suicide not old, resistance to cold and summer-heat.” The traditional Chinese medical science is commonly used it to treat hepatic and renal YIN deficiency, soreness of the waist and knees, dizziness, forgetful, dizzy, the many tear of blurred vision, the disease such as quench one's thirst, pass out semen.Existing Confirm for pharmaceutical research, Fructus Lycii scalable body's immunity, can effectively suppress growth of tumour cell and cell mutation, tool There are slow down aging, anti-fatty liver, adjust blood fat and blood glucose, promote the aspects such as hemopoietic function, and be applied to clinic.
Radix Salviae Miltiorrhizae has the effect of blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia, relieving restlessness that clears away heart-fire, cool blood to disappear carbuncle.For obstruction of qi in the chest and cardialgia, gastral cavity abdomen is coerced Bitterly, abdominal mass abdominal mass accumulation, hot numbness pain, dysphoria and insomnia, menoxenia, dysmenorrhea amenorrhea, sore swell and ache curative.
Beneficial effects of the present invention: collyrium of the present invention is that various raw materials obtain after compatibility, have inducing diuresis to remove edema, clear Thermal detoxification, pain relieving pathogenic fire purging, the effect of liver heat removing and eyesight improving, ocular muscle dystrophy, fatigue obstructed to the various inflammation of eyes, blood capillary, god There is good therapeutic effect through numbness etc., can not only effectively alleviate that eye is dry and astringent and slight sense of discomfort is moreover it is possible to play moistening improving eyesight Effect, should be widely promoted application.
Specific embodiment
With reference to embodiment, the present invention is described further, but protection scope of the present invention is not limited to that.
Embodiment 1
A kind of Traditional Chinese medicine eye drop, is made up of the raw material of following weight portion: 50 parts of Cortex Mori, 3 parts of Rhizoma Coptidis, 2 parts of Cortex Phellodendri, Radix Scutellariae 2 Part, 3 parts of Borneolum Syntheticum, 2 parts of Radix Glycyrrhizae, 9 parts of Semen Cassiae, 7 parts of Folium Bambusae, 4 parts of Flos Lonicerae, 6.5 parts of Fructus Lycii, 4 parts of Radix Salviae Miltiorrhizae.
The preparation method of Traditional Chinese medicine eye drop, comprises the following steps: (1) is by Cortex Mori, Rhizoma Coptidis, Cortex Phellodendri, Radix Scutellariae, Radix Glycyrrhizae, Semen Cassiae Obtain mixture after son, Folium Bambusae, Flos Lonicerae, Fructus Lycii, Radix Salviae Miltiorrhizae co-grinding are uniform, add the water of 7 times of mixture quality, boil After 3.5h, filter to get filtrate;
(2) filtrate heating is concentrated to give concentrated solution, the volume of concentrated solution is the 5/12 of filtrate, and concentrated solution carries in 70 DEG C of distillations Liquid must be purified within pure 2 hours, in purification liquid, add Borneolum Syntheticum mix homogeneously.
Embodiment 2
A kind of Traditional Chinese medicine eye drop, is made up of the raw material of following weight portion: 40 parts of Cortex Mori, 1 part of Rhizoma Coptidis, 1 part of Cortex Phellodendri, Radix Scutellariae 1 Part, 2 parts of Borneolum Syntheticum, 1.5 parts of Radix Glycyrrhizae, 6 parts of Semen Cassiae, 5 parts of Folium Bambusae, 3 parts of Flos Lonicerae, 3 parts of Fructus Lycii, 2 parts of Radix Salviae Miltiorrhizae.
The preparation method of Traditional Chinese medicine eye drop, comprises the following steps: (1) is by Cortex Mori, Rhizoma Coptidis, Cortex Phellodendri, Radix Scutellariae, Radix Glycyrrhizae, Semen Cassiae Obtain mixture after son, Folium Bambusae, Flos Lonicerae, Fructus Lycii, Radix Salviae Miltiorrhizae co-grinding are uniform, add the water of 6 times of mixture quality, boil 2h Afterwards, filter to get filtrate;
(2) filtrate heating is concentrated to give concentrated solution, the volume of concentrated solution is the 1/3 of filtrate, and concentrated solution carries in 60 DEG C of distillations Liquid must be purified within pure 1 hour, in purification liquid, add Borneolum Syntheticum mix homogeneously.
Embodiment 3
A kind of Traditional Chinese medicine eye drop, is made up of the raw material of following weight portion: 60 parts of Cortex Mori, 5 parts of Rhizoma Coptidis, 3 parts of Cortex Phellodendri, Radix Scutellariae 4 Part, 4 parts of Borneolum Syntheticum, 3.5 parts of Radix Glycyrrhizae, 12 parts of Semen Cassiae, 9 parts of Folium Bambusae, 6 parts of Flos Lonicerae, 9 parts of Fructus Lycii, 6 parts of Radix Salviae Miltiorrhizae.
The preparation method of Traditional Chinese medicine eye drop, comprises the following steps: (1) is by Cortex Mori, Rhizoma Coptidis, Cortex Phellodendri, Radix Scutellariae, Radix Glycyrrhizae, Semen Cassiae Obtain mixture after son, Folium Bambusae, Flos Lonicerae, Fructus Lycii, Radix Salviae Miltiorrhizae co-grinding are uniform, add the water of 8 times of mixture quality, boil 5h Afterwards, filter to get filtrate;
(2) filtrate heating is concentrated to give concentrated solution, the volume of concentrated solution is the 1/2 of filtrate, and concentrated solution carries in 80 DEG C of distillations Liquid must be purified within pure 3 hours, in purification liquid, add Borneolum Syntheticum mix homogeneously.
Embodiment 4
A kind of Traditional Chinese medicine eye drop, is made up of the raw material of following weight portion: 48 parts of Cortex Mori, 2 parts of Rhizoma Coptidis, 1.5 parts of Cortex Phellodendri, Radix Scutellariae 1.5 parts, 2.5 parts of Borneolum Syntheticum, 1.7 parts of Radix Glycyrrhizae, 8 parts of Semen Cassiae, 6 parts of Folium Bambusae, 4 parts of Flos Lonicerae, 6 parts of Fructus Lycii, 3 parts of Radix Salviae Miltiorrhizae.
The preparation method of Traditional Chinese medicine eye drop, comprises the following steps: (1) is by Cortex Mori, Rhizoma Coptidis, Cortex Phellodendri, Radix Scutellariae, Radix Glycyrrhizae, Semen Cassiae Obtain mixture after son, Folium Bambusae, Flos Lonicerae, Fructus Lycii, Radix Salviae Miltiorrhizae co-grinding are uniform, add the water of 6.5 times of mixture quality, boil After 3h, filter to get filtrate;
(2) filtrate heating is concentrated to give concentrated solution, the volume of concentrated solution is the 1/3 of filtrate, and concentrated solution carries in 65 DEG C of distillations Liquid must be purified within pure 1.5 hours, in purification liquid, add Borneolum Syntheticum mix homogeneously.
Embodiment 5
A kind of Traditional Chinese medicine eye drop, is made up of the raw material of following weight portion: 52 parts of Cortex Mori, 4 parts of Rhizoma Coptidis, 2.5 parts of Cortex Phellodendri, Radix Scutellariae 3 parts, 3.5 parts of Borneolum Syntheticum, 2.3 parts of Radix Glycyrrhizae, 10 parts of Semen Cassiae, 8 parts of Folium Bambusae, 5 parts of Flos Lonicerae, 7 parts of Fructus Lycii, 5 parts of Radix Salviae Miltiorrhizae.
The preparation method of Traditional Chinese medicine eye drop, comprises the following steps: (1) is by Cortex Mori, Rhizoma Coptidis, Cortex Phellodendri, Radix Scutellariae, Radix Glycyrrhizae, Semen Cassiae Obtain mixture after son, Folium Bambusae, Flos Lonicerae, Fructus Lycii, Radix Salviae Miltiorrhizae co-grinding are uniform, add the water of 7.5 times of mixture quality, boil After 4h, filter to get filtrate;
(2) filtrate heating is concentrated to give concentrated solution, the volume of concentrated solution is the 1/2 of filtrate, and concentrated solution carries in 75 DEG C of distillations Liquid must be purified within pure 2.5 hours, in purification liquid, add Borneolum Syntheticum mix homogeneously.
In order to prove the effect of Traditional Chinese medicine eye drop of the present invention further, carry out clinical examination from the collyrium in embodiment 1 Test, subjects are the patient 100 of ophthalmic uncomfortable, and using method is: the collyrium of the embodiment of the present invention 1 is instilled ophthalmic, 4-6 time on the one, one time 2-3 drips;After 5 days, after testing, eye symptom improver is 99, and effective percentage is 99%, wherein controls More person is 97, and cure rate is 97%.
Model case is as follows: 1, Lee χ χ, man, 16 years old, Jinan, Shandong Province people, student, and because study is nervous, frequent evening is learned Practise, make eyes form pseudomyopia, after collyrium of the present invention 5 days, vision restoration is normal.
2nd, open χ χ, female, 28 years old, Qingdao, white collar, because of job demand, use computer overlong time, it is tired that eyes suffer from serious vision Labor disease, after collyrium of the present invention 5 days, visual fatigue has recovered, and is continuing with, and eye recovers normal.
3rd, king χ χ, man, 32 years old, Hok-lo, because of frequent contact lens, conjunctival hemorrhage in eye.Using this Bright collyrium is after five days, remission.
4th, Zhao χ χ, female, 65 years old, people from Changsha, retired worker, is in after retirement and has nothing to do, often see TV, play Game, eyes suffer from serious eyestrain symptoms, and after collyrium of the present invention 5 days, visual fatigue mitigates, and vision restoration is normal.
By above clinical test results understand Traditional Chinese medicine eye drop of the present invention obstructed to the various inflammation of eyes, blood capillary, Ocular muscle dystrophy, fatigue, nerve numb etc. have good therapeutic effect, can not only effectively alleviate that eye is dry and astringent and slight sense of discomfort, The effect of moistening improving eyesight can also be played, should be widely promoted application.

Claims (4)

1. a kind of Traditional Chinese medicine eye drop is it is characterised in that be made up of the raw material of following weight portion: 40~60 parts of Cortex Mori, Rhizoma Coptidis 1~5 Part, 1~3 part of Cortex Phellodendri, 1~4 part of Radix Scutellariae, 2~4 parts of Borneolum Syntheticum, 1.5~3.5 parts of Radix Glycyrrhizae, 6~12 parts of Semen Cassiae, 5~9 parts of Folium Bambusae, 3~6 parts of Flos Lonicerae, 3~9 parts of Fructus Lycii, 2~6 parts of Radix Salviae Miltiorrhizae.
2. as claimed in claim 1 a kind of Traditional Chinese medicine eye drop it is characterised in that being made up of the raw material of following weight portion: Cortex Mori 48~52 parts, 2~4 parts of Rhizoma Coptidis, 1.5~2.5 parts of Cortex Phellodendri, 1.5~3 parts of Radix Scutellariae, 2.5~3.5 parts of Borneolum Syntheticum, Radix Glycyrrhizae 1.7~2.3 Part, 8~10 parts of Semen Cassiae, 6~8 parts of Folium Bambusae, 4~5 parts of Flos Lonicerae, 6~7 parts of Fructus Lycii, 3~5 parts of Radix Salviae Miltiorrhizae.
3. as claimed in claim 2 a kind of Traditional Chinese medicine eye drop it is characterised in that being made up of the raw material of following weight portion: Cortex Mori 50 parts, 3 parts of Rhizoma Coptidis, 2 parts of Cortex Phellodendri, 2 parts of Radix Scutellariae, 3 parts of Borneolum Syntheticum, 2 parts of Radix Glycyrrhizae, 9 parts of Semen Cassiae, 7 parts of Folium Bambusae, 4 parts of Flos Lonicerae, Fructus Lycii Sub 6.5 parts, 4 parts of Radix Salviae Miltiorrhizae.
4. the preparation method of the arbitrary described Traditional Chinese medicine eye drop of claim 1-3 is it is characterised in that comprise the following steps:
(1) will be uniform to Cortex Mori, Rhizoma Coptidis, Cortex Phellodendri, Radix Scutellariae, Radix Glycyrrhizae, Semen Cassiae, Folium Bambusae, Flos Lonicerae, Fructus Lycii, Radix Salviae Miltiorrhizae co-grinding Obtain mixture afterwards, add the water of 6-8 times of mixture quality, after boiling 2-5h, filter to get filtrate;
(2) filtrate heating is concentrated to give concentrated solution, the volume of concentrated solution is the 1/3~1/2 of filtrate, and concentrated solution steams at 60-80 DEG C Evaporate purification 1-3 hour and must purify liquid, in purification liquid, add Borneolum Syntheticum mix homogeneously.
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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107929356A (en) * 2017-12-28 2018-04-20 龙欢乐 Eyedrops and its preparation method and application
CN108904778A (en) * 2018-09-28 2018-11-30 永州职业技术学院 A kind of collyrium for alleviating visual fatigue
CN111346191A (en) * 2018-12-24 2020-06-30 智德明创生物科技(北京)有限公司 Traditional Chinese medicine eye patch for treating meibomian gland dysfunction xerophthalmia and preparation method thereof
CN112294900A (en) * 2020-11-05 2021-02-02 新疆悦弘生物科技有限公司 Eye-protecting liquid and preparation method thereof

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103393969A (en) * 2013-08-03 2013-11-20 吴春子 Eye drop used for releasing eye fatigue and preparation method thereof
CN103638432A (en) * 2013-11-27 2014-03-19 许伟 Traditional Chinese medicine eye drop

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103393969A (en) * 2013-08-03 2013-11-20 吴春子 Eye drop used for releasing eye fatigue and preparation method thereof
CN103638432A (en) * 2013-11-27 2014-03-19 许伟 Traditional Chinese medicine eye drop

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107929356A (en) * 2017-12-28 2018-04-20 龙欢乐 Eyedrops and its preparation method and application
CN107929356B (en) * 2017-12-28 2021-02-12 龙欢乐 Eye drop and preparation method and application thereof
CN108904778A (en) * 2018-09-28 2018-11-30 永州职业技术学院 A kind of collyrium for alleviating visual fatigue
CN111346191A (en) * 2018-12-24 2020-06-30 智德明创生物科技(北京)有限公司 Traditional Chinese medicine eye patch for treating meibomian gland dysfunction xerophthalmia and preparation method thereof
CN112294900A (en) * 2020-11-05 2021-02-02 新疆悦弘生物科技有限公司 Eye-protecting liquid and preparation method thereof

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