CN105663656A - Pharmaceutical composition for treating sleep disorders and preparing method thereof - Google Patents
Pharmaceutical composition for treating sleep disorders and preparing method thereof Download PDFInfo
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Abstract
The invention belongs to the technical field of traditional Chinese medicine and aims to provide a pharmaceutical composition for treating sleep disorders according to the understanding mechanism of traditional Chinese medicine for sleep disorders. The pharmaceutical composition is prepared from, by mass, 10-16 parts of glossy ganoderma, 10-22 parts of caulis polygoni multiflori, 10-16 parts of semen boitae, 3-12 parts of radix polygalae, 10-16 parts of cortex albiziae, 10-32 parts of mother-of-pearl, 15-25 parts of poria with hostwood, 6-16 parts of spina date seed, 3-8 parts of Chinese magnolcavine fruit, 12-35 parts of radix rehmanniae praeparata, 10-20 parts of lycium chinensis, 5-16 parts of root of red-rooted salvia, 6-16 parts of core-removed radix ophiopogonis and 3-8 parts of pinellia ternate. The pharmaceutical composition can treat both symptoms and root causes.
Description
Technical field
The present invention relates to technical field of Chinese medicine, be specifically related to a kind of Chinese medicine composition for treating sleep disorder, especially for the field of the Chinese medicine composition that sleep disorder patient uses and preparation method thereof.
Background technology
Along with modernization quickening, operating pressure aggravation, night life and the reason such as bad life habits and aged tendency of population, quite a few people is chronically at insomnia, depressive state, even some people is barren spiritually and takes drugs, and causes hypoimmunity, becomes the Susceptible population of antibacterial, virus. Chronic insomnia can cause and bring out mental sickness, promotes the generation accident of hypertension, cardiovascular and cerebrovascular disease. Investigating according to World Health Organization (WHO), there are sleeping problems in the people in the whole world nearly 1/3rd. Six big city such as Beijing, Shanghai survey data in 2013 shows, the people of 59% in the previous year in once had a sleepless night and perplexed, had a strong impact on quality of life and work efficiency. According to the 4th Asia sleep medicine conference epidemiologic data introduction in 2011, sleep disorder reached 50% at Asia sickness rate. International mental healths in 2009 and neurological foundation (MF-HN) survey data show, there is insomnia problem in the crowd having 45.5% in China general population, in inpatient, the sickness rate of insomnia is higher than 50%, and owing to contemporary work and rhythm of life are accelerated, the sickness rate of insomnia is in rising trend. Sleep disorder has become great public health problem and the social problem of puzzlement human health and social development.
So, just how to find a kind of Chinese medicine composition that can effectively treat sleep disorder, be our current problem in urgent need to solve.
Summary of the invention
Development along with China's Chinese medicine, on treatment sleep disorder, the advantage that people appreciate the above-mentioned sleep disorder of Chinese traditional treatment gradually, and the advantage such as toxic and side effects is little over the course for the treatment of, expense is low, present situation for the above-mentioned sleep disorder of existing western medical treatment, it is an object of the invention to be in that to provide a kind of Chinese medicine composition for treating sleep disorder, to solve sleep disorder patient restorative problem early. This medicine is with common Chinese medicine for raw material, has instant effect, the feature such as evident in efficacy, and can effectively treat above-mentioned sleep disorder.
For reaching the purpose of foregoing invention, the technical solution adopted in the present invention is: provide a kind of for Chinese medicine composition treating sleep disorder and preparation method thereof, it is characterised in that each component and the mass parts ratio of described Chinese medicine composition are as follows:
Ganoderma 10～16g, Caulis Polygoni Multiflori 10～22g, Semen Platycladi 10～16g, Radix Polygalae 3～12g, Cortex Albiziae 10～16g, Concha Margaritifera 10～32g, Poria cum Radix Pini 15～25g, Semen Ziziphi Spinosae 6～16g, Fructus Schisandrae Chinensis 3～8g, Radix Rehmanniae Preparata 12～35g, Fructus Lycii 10～20g, Radix Salviae Miltiorrhizae 5～16g, Radix Ophiopogonis (removing the heart) 6～16g, the Rhizoma Pinelliae 3～8g.
A kind of for Chinese medicine composition treating sleep disorder and preparation method thereof, it is characterised in that each component and the mass parts ratio of described Chinese medicine composition are as follows:
Ganoderma 11～14g, Caulis Polygoni Multiflori 12～19g, Semen Platycladi 11～14g, Radix Polygalae 6～11g, Cortex Albiziae 11～14g, Concha Margaritifera 20～28g, Poria cum Radix Pini 18～22g, Semen Ziziphi Spinosae 8～14g, Fructus Schisandrae Chinensis 5～7g, Radix Rehmanniae Preparata 20～31g, Fructus Lycii 12～17g, Radix Salviae Miltiorrhizae 8～14g, Radix Ophiopogonis (removing the heart) 8～14g, the Rhizoma Pinelliae 5～7g.
A kind of for Chinese medicine composition treating sleep disorder and preparation method thereof, it is characterised in that each component and the mass parts ratio of the Chinese medicine composition of described " preferred plan " are as follows:
Ganoderma 12g, Caulis Polygoni Multiflori 17g, Semen Platycladi 13g, Radix Polygalae 10g, Cortex Albiziae 13g, Concha Margaritifera 25g, Poria cum Radix Pini 20g, Semen Ziziphi Spinosae 13g, Fructus Schisandrae Chinensis 6g, Radix Rehmanniae Preparata 26g, Fructus Lycii 15g, Radix Salviae Miltiorrhizae 13g, Radix Ophiopogonis (removing the heart) 13g, Rhizoma Pinelliae 6.5g.
A kind of for Chinese medicine composition treating sleep disorder and preparation method thereof, it is characterised in that described method comprises the steps to be prepared from:
B, the method traditionally preparing Chinese medicine capsules, after being sieved by ground superfine myrrh thing, putting into mix homogeneously in medicine device, (the sealed rear total length of its capsule is 23.3mm then to prepare into capsule, medicated powder capacity 0.4～0.5g/ grain), and then sealed packaging is standby.
A kind of for Chinese medicine composition treating sleep disorder and preparation method thereof, it is characterised in that described instructions of taking is: by the capsule prepared to take once a day, dosage 2.5g/ time sleeps front clothes, takes medicine 15～30 days, and sleep improvement, disease obtains recovery from illness.
Each raw material Chinese medicine in prescription of the present invention is all documented in detail in Chinese Pharmacopoeia, China's dictionary and China's book on Chinese herbal medicine. The present invention selects most common of which Chinese medicine to be raw material, gives full play to the pharmacological effect of each component:
Ganoderma, nature and flavor: Gan Ping, warm in nature, there is effect of replenishing QI and blood, tranquilizing mind, strengthening the spleen and stomach, be used for treating asthenia, cardiopalmus, insomnia, dizziness, spiritlessness and weakness, chronic cough asthma, coronary heart disease, pneumosilicosis, tumor;
Caulis Polygoni Multiflori, nature and flavor: hardship sweet, micro-, property are flat, there is tranquilizing by nourishing the heart, dispel the wind, effect of dredging collateral, be used for treating insomnia, dreaminess, blood deficiency general pain, numbness of the skin, rheumatic arthralgia, rubella pruritus;
Semen Platycladi, nature and flavor: sweet, property is put down, and has effect of tranquilizing by nourishing the heart, arresting sweating, loosening bowel to relieve constipation, it is used for treating palpitation with fear palpitation with a distress feeling, insomnia forgetfulness, night sweat, dryness of the intestine constipation;
Radix Polygalae, nature and flavor: bitter, pungent, tepor, the effect there is Fructus Alpiniae Oxyphyllae of calming the nerves, eliminate the phlegm, subsiding a swelling, for treating that the insomnia and dreamful sleep that disarmony between the heart and kidney causes, forgetful palpitation with fear, staring spells, expectoration be not well, sore swollen toxin, breast swell and pain;
Cortex Albiziae, nature and flavor: sweet, flat, there is resolving depression of calming the nerves, the effect of eliminating carbuncle of invigorating blood circulation, be used for treating irritability, melancholy, sleeplessness, inside and outside carbuncle and ulcer, traumatic injury;
Concha Margaritifera, nature and flavor: sweet in the mouth, salty, cold in nature, there is suppressing the hyperactive liver and subsiding YANG, effect of calm the nerves arresting convulsion, liver heat removing and eyesight improving, be used for treating headache dizziness, palpitation and insomnia, demented infantile convulsion, liver-heat conjunctival congestion, pterygium;
Poria cum Radix Pini, nature and flavor: sweet light, flat, there is mind calming, calm the nerves, effect of diuretic, have a guilty conscience palpitation with fear, forgetful, insomnia, infantile convulsion, dysuria for treatment;
Semen Ziziphi Spinosae, nature and flavor: sweet, flat, there is effect of mind tranquilizing and the heart calming, nourishing the liver, arresting sweating, be used for treating restlessness of asrhenia type and insomnia, palpitation with fear palpitation with a distress feeling, body void spontaneous perspiration, night sweat;
Fructus Schisandrae Chinensis, nature and flavor: sour, sweet, warm, there is effect of astringent or styptic treatment for spontaneous sweating, the supplementing QI for promoting the production of body fluid of convergence, kidney calming, be used for treating incessant chronic diarrhea, chronic cough dyspnea due to deficiency, cardiopalmus, insomnia, dreaminess, spontaneous perspiration, night sweat, Tianjin wound is thirsty, quench one's thirst, pass out semen, spermatorrhea;
Radix Rehmanniae Preparata, nature and flavor: sweet, tepor, have nourishing YIN and supplementing blood, benefit essence fills out effect of marrow, be used for treating the hepatic and renal YIN deficiency, soreness of the waist and knees, osteopyrexia and fever, night sweat seminal emission, interior-heat are quenched one's thirst, blood deficiency and yellow complexion, severe palpitation, menoxenia, metrostaxis, dizziness, tinnitus, early whitening of beard and hair;
Fructus Lycii, nature and flavor: sweet in the mouth, property are flat, have effect of nourishing the liver, nourishing kidney, lung moistening, be used for treating caused by liver and kidney deficiency, have a dizzy spell, visual one clear, the expensive essence of soreness of the waist and knees, sexual impotence, cough due to consumptive disease, the diseases such as taking fluids profusely of quenching one's thirst;
Radix Salviae Miltiorrhizae, nature and flavor: bitter in the mouth, cold nature, there is effect of blood circulation promoting and blood stasis dispelling, menstruction regulating and pain relieving, nourishing blood to tranquillize the mind, removing heat from blood eliminating carbuncle, be used for treating menoxenia, dysmenorrhea, amenorrhea, puerperal the stagnant stomachache of the stasis of blood, trusted subordinate's pain, lump in the abdomen, pyretic arthralgia swell and ache, the disease such as traumatic injury, heat enter nutrient blood, dysphoria, vexed insomnia, ulcerative carbuncle toxic swelling;
Radix Ophiopogonis (removes the heart), nature and flavor: hardship sweet, micro-is slightly cold, and has nourishing YIN and moistening the lung, effect that stomach reinforcing clears away heart-fire, is used for treating the diseases such as lung-dryness syndrome due to deficiency of YIN, dry cough expectorant is thick, chronic cough spitting of blood, Tianjin few insomnia thirsty, vexed, dryness of the intestine constipation;
The Rhizoma Pinelliae, nature and flavor: acrid in the mouth, warm in nature, poisonous, there is effect of drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass, be used for treating cough with asthma abundant expectoration, vomiting regurgitation, feeling of oppression and fullness in the chest and epigastrium headache dizziness, uneasy sleeping at night, gall subcutaneous nodule, swollen ulcer drug.
Medicine of the present invention is based on the differential diagnosis of diseases of Chinese traditional treatment sleep disorder and the dialectical principle combined, think from pharmacological action and mechanism of action: with regard to sleep disorder one disease, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, and above-mentioned disease is had good therapeutic effect.
Detailed description of the invention
The present invention is aiming at the treatment of above-mentioned sleep disorder and a kind of Chinese medicine formula of proposing, adopts medicine effect prepared by this formula good, and instant effect, is the Chinese prescription of a treating both the principal and secondary aspects of a disease, is particularly suitable for Clinical practice. It is described in further detail below in conjunction with the specific embodiment of the present invention:
Embodiment 1:
A kind of Chinese medicine composition for treating sleep disorder, it is characterised in that each component of described Chinese medicine composition and mass parts ratio are as follows:
Ganoderma 12g, Caulis Polygoni Multiflori 17g, Semen Platycladi 13g, Radix Polygalae 10g, Cortex Albiziae 13g, Concha Margaritifera 25g, Poria cum Radix Pini 20g, Semen Ziziphi Spinosae 13g, Fructus Schisandrae Chinensis 6g, Radix Rehmanniae Preparata 26g, Fructus Lycii 15g, Radix Salviae Miltiorrhizae 13g, Radix Ophiopogonis (removing the heart) 13g, Rhizoma Pinelliae 6.5g.
Embodiment 2:
A kind of Chinese medicine composition for treating sleep disorder, it is characterised in that each component of described Chinese medicine composition and mass parts ratio are as follows:
Ganoderma 14g, Caulis Polygoni Multiflori 19g, Semen Platycladi 14g, Radix Polygalae 11g, Cortex Albiziae 14g, Concha Margaritifera 28g, Poria cum Radix Pini 22g, Semen Ziziphi Spinosae 14g, Fructus Schisandrae Chinensis 7g, Radix Rehmanniae Preparata 31g, Fructus Lycii 17g, Radix Salviae Miltiorrhizae 14g, Radix Ophiopogonis (removing the heart) 14g, Rhizoma Pinelliae 7g.
Embodiment 3:
A kind of Chinese medicine composition for treating sleep disorder, it is characterised in that each component of described Chinese medicine composition and mass parts ratio are as follows:
Ganoderma 16g, Caulis Polygoni Multiflori 22g, Semen Platycladi 16g, Radix Polygalae 12g, Cortex Albiziae 16g, Concha Margaritifera 32g, Poria cum Radix Pini 25g, Semen Ziziphi Spinosae 16g, Fructus Schisandrae Chinensis 8g, Radix Rehmanniae Preparata 35g, Fructus Lycii 20g, Radix Salviae Miltiorrhizae 16g, Radix Ophiopogonis (removing the heart) 16g, Rhizoma Pinelliae 8g.
Model case:
Through clinical conditions sleep disorder patient totally 110 example, the age is 80 examples of more than 58 years old, and only 30 examples are less than 58 years old.90 examples of recovery from illness in 110 example patients, 20 effective examples, total effective rate reaches 100%. After treatment, sleep improvement, disease obtains recovery from illness.
Claims (3)
1. the Chinese medicine composition being used for treating sleep disorder, it is characterised in that each component of described Chinese medicine composition and mass parts ratio thereof are as follows:
Ganoderma 10～16g, Caulis Polygoni Multiflori 10～22g, Semen Platycladi 10～16g, Radix Polygalae 3～12g, Cortex Albiziae 10～16g, Concha Margaritifera 10～32g, Poria cum Radix Pini 15～25g, Semen Ziziphi Spinosae 6～16g, Fructus Schisandrae Chinensis 3～8g, Radix Rehmanniae Preparata 12～35g, Fructus Lycii 10～20g, Radix Salviae Miltiorrhizae 5～16g, Radix Ophiopogonis (removing the heart) 6～16g, the Rhizoma Pinelliae 3～8g.
2. the Chinese medicine composition for treating sleep disorder according to claim 1, it is characterised in that each component of described Chinese medicine composition and mass parts ratio thereof are as follows:
Ganoderma 11～14g, Caulis Polygoni Multiflori 12～19g, Semen Platycladi 11～14g, Radix Polygalae 6～11g, Cortex Albiziae 11～14g, Concha Margaritifera 20～28g, Poria cum Radix Pini 18～22g, Semen Ziziphi Spinosae 8～14g, Fructus Schisandrae Chinensis 5～7g, Radix Rehmanniae Preparata 20～31g, Fructus Lycii 12～17g, Radix Salviae Miltiorrhizae 8～14g, Radix Ophiopogonis (removing the heart) 8～14g, the Rhizoma Pinelliae 5～7g.
3. the Chinese medicine composition for treating sleep disorder according to claim 1 to 2, it is characterised in that each component of described Chinese medicine composition and mass parts ratio thereof are as follows:
Ganoderma 12g, Caulis Polygoni Multiflori 17g, Semen Platycladi 13g, Radix Polygalae 10g, Cortex Albiziae 13g, Concha Margaritifera 25g, Poria cum Radix Pini 20g, Semen Ziziphi Spinosae 13g, Fructus Schisandrae Chinensis 6g, Radix Rehmanniae Preparata 26g, Fructus Lycii 15g, Radix Salviae Miltiorrhizae 13g, Radix Ophiopogonis (removing the heart) 13g, Rhizoma Pinelliae 6.5g.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105943649A (en) * | 2016-06-28 | 2016-09-21 | 杨大妹 | Chinese prescription for treating skin edema |
| CN106266709A (en) * | 2016-09-19 | 2017-01-04 | 四川易创生物科技有限公司 | A kind of Chinese medicine preparation treating sleep disorder and preparation method thereof |
| CN107029125A (en) * | 2017-06-08 | 2017-08-11 | 湖南云从科技有限公司 | A kind of calm the nerves improves granule medicament formula of sleep and preparation method thereof |
| CN107349294A (en) * | 2017-09-11 | 2017-11-17 | 黄大帅 | A kind of bubble pin health-care Chinese medicinal composition of tranquilizing and preparation method thereof |
-
2016
- 2016-03-17 CN CN201610151747.6A patent/CN105663656A/en not_active Withdrawn
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105943649A (en) * | 2016-06-28 | 2016-09-21 | 杨大妹 | Chinese prescription for treating skin edema |
| CN106266709A (en) * | 2016-09-19 | 2017-01-04 | 四川易创生物科技有限公司 | A kind of Chinese medicine preparation treating sleep disorder and preparation method thereof |
| CN107029125A (en) * | 2017-06-08 | 2017-08-11 | 湖南云从科技有限公司 | A kind of calm the nerves improves granule medicament formula of sleep and preparation method thereof |
| CN107349294A (en) * | 2017-09-11 | 2017-11-17 | 黄大帅 | A kind of bubble pin health-care Chinese medicinal composition of tranquilizing and preparation method thereof |
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Application publication date: 20160615 |