CN112294900A - Eye-protecting liquid and preparation method thereof - Google Patents
Eye-protecting liquid and preparation method thereof Download PDFInfo
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Abstract
The invention relates to an eye-protecting liquid and a preparation method thereof, wherein ginseng, mulberry leaf, angelica dahurica, salvia miltiorrhiza, grassleaf sweelflag rhizome, pearl, abalone shell, coptis chinensis, angelica, medlar, tuckahoe and the like are adopted as raw materials, and the biological active ingredients in the raw materials are retained to the maximum extent through advanced processes such as strict screening, ethanol extraction, PBS solution extraction, vacuum concentration and the like, and are reasonably matched, so that the finished product achieves a better eye-protecting effect; the eye protection liquid disclosed by the invention is mainly antibacterial and bacteriostatic, has the effects of improving eyesight and nebula, inducing resuscitation and refreshing mind, has the effects of diminishing inflammation, repairing and improving immunity, has a conditioning effect on relieving eye fatigue, eye dryness and tearing in the wind, and can improve the prevention capability of eye diseases.
Description
Technical Field
The invention belongs to the field of eye protection liquid, and particularly relates to eye protection liquid and a preparation method thereof.
Background
The eye protecting liquid is one of the most common medicine preparation forms for treating eye diseases, and has direct and fast treating effect on a plurality of eye diseases. With the change of life style and working conditions of people, people have more and more time to use eyes, such as watching computers, watching televisions, playing electronic games and the like for a long time, and are easy to suffer from visual fatigue and dry eye syndrome. Most of the existing eye protection solutions have side effects and contain chemical components.
In view of this, this patent is filed.
Disclosure of Invention
In order to solve the problems in the prior art, the invention provides eye protection liquid and a preparation method thereof. The eye protection liquid is prepared by extracting pure plants, is safe, has no toxic or side effect, has the mutual cooperation of the raw materials, and has the effects of resisting and inhibiting bacteria, improving eyesight, removing nebula, inducing resuscitation and refreshing mind.
One object of the present invention is to provide an eye-protecting solution.
The invention also aims to provide a preparation method of the eye-protecting liquid.
According to the specific embodiment of the invention, the eye-protecting solution is prepared from the following raw materials: ginseng, mulberry leaf, angelica dahurica, salvia miltiorrhiza, grassleaf sweelflag rhizome, pearl, abalone shell, coptis chinensis, angelica, medlar and tuckahoe.
The eye-protecting solution is prepared from the following raw materials in parts by weight: the eye protection solution is prepared from the following raw materials in parts by weight: 4-6 parts of ginseng, 1-3 parts of mulberry leaf, 1-3 parts of angelica dahurica, 2-4 parts of salvia miltiorrhiza, 2-4 parts of rhizoma acori graminei, 4-6 parts of pearl, 4-6 parts of abalone shell, 1-3 parts of coptis chinensis, 1-3 parts of angelica sinensis, 2-5 parts of wolfberry fruit and 4-8 parts of poria cocos.
The eye-protecting solution is prepared from the following raw materials in parts by weight: 5 parts of ginseng, 2 parts of mulberry leaf, 2 parts of angelica dahurica, 3 parts of salvia miltiorrhiza, 3 parts of grassleaf sweelflag rhizome, 5 parts of pearl, 5 parts of abalone shell, 2 parts of coptis chinensis, 2 parts of angelica, 3 parts of medlar and 6 parts of tuckahoe.
The eye-protecting liquid according to the specific embodiment of the invention, wherein the pearl is pearl powder, and the particle fineness of the pearl powder is 100-200 meshes.
The preparation method of the eye-protecting solution according to the embodiment of the invention comprises the following steps:
(1) weighing mulberry leaves, angelica dahurica, rhizoma acori graminei, concha haliotidis, coptis chinensis, angelica sinensis, wolfberry fruits and poria cocos according to a proportion, respectively crushing, then mixing, and uniformly mixing to form a material to be extracted;
(2) adding distilled water and a PBS solution into the material to be extracted obtained in the step (1), soaking for 3-5 hours, then decocting for 35-45 minutes with slow fire for the first time, filtering, and collecting the first filtrate; adding distilled water and PBS solution into the filter residue, decocting with slow fire for 35-45 min for the second time, filtering, and collecting the second filtrate; combining the first filtrate and the second filtrate to form an extract;
(3) weighing ginseng and salvia miltiorrhiza according to a proportion, respectively crushing to 100-200 meshes, then mixing, uniformly mixing to form a material to be extracted, soaking the material to be extracted for 10-14 hours by using 60-90% ethanol as a solvent, filtering, collecting filtrate, recovering ethanol, concentrating into paste, vacuum drying, crushing to form two mixed powders of ginseng and salvia miltiorrhiza;
(4) and (3) adding the two mixed powders obtained in the step (3) and pearls into the extracting solution obtained in the step (2), uniformly mixing, concentrating, filtering again, sterilizing, cooling and subpackaging to obtain the eye protection solution.
According to the preparation method of the eye-protecting liquid, the particle fineness of the crushed eye-protecting liquid in the step (1) is 80-100 meshes.
According to the preparation method of the eye-protecting liquid, the addition amount of the distilled water and the PBS solution is 6-10 times of the weight of the material to be extracted or the filter residue.
According to the preparation method of the eye-protecting liquid of the embodiment of the invention, the adding amount ratio of the distilled water and the PBS solution is 1:1.
According to the preparation method of the eye-protecting solution of the embodiment of the invention, in the step (2), the PBS solution has a pH of 7.4.
According to the preparation method of the eye-protecting liquid, the temperature of the mild fire in the step (2) is 65-75 ℃.
According to the preparation method of the eye-protecting liquid, the pearl is added into the extracting solution in the step (4), the pearl and the extracting solution are uniformly mixed to form a material to be concentrated, and the material to be concentrated is concentrated at the temperature of 60-70 ℃ until the mass of the material to be concentrated is 60%; the sterilization adopts high-pressure steam sterilization.
According to the preparation method of the eye-protecting liquid, the eye-protecting liquid is prepared, wherein in the steps (2) to (4), the filtration is performed by sieving with a 400-mesh sieve.
Abalone shell, cold in nature, salty in taste; entering liver meridian; pacify liver and subdue yang, clear liver heat and improve vision. Liver yang-calming herbs belonging to the category of liver-calming and wind-calming herbs; it can be used for treating headache, vertigo, conjunctival congestion, nebula, blurred vision, and night blindness.
Mulberry leaf, sweet, bitter and cold; entering lung and liver meridians; mainly treats the functions of dispelling wind and heat, clearing lung and moistening dryness, and clearing liver and improving vision. Can be used for treating wind-heat type common cold, lung heat type cough, dizziness, headache, conjunctival congestion, and dim eyesight.
Dahurian angelica root, pungent and warm; entering stomach, large intestine and lung meridians; the main functions are dispelling wind and eliminating dampness, promoting the restoration consciousness and relieving pain, and detumescence and draining pus. Can be used for treating common cold, headache, supraorbital bone pain, nasal obstruction, nasosinusitis, toothache, leucorrhea, and pyocutaneous disease with swelling and pain.
Grassleaf sweelflag rhizome, pungent, bitter and warm; heart and stomach meridians entered; mainly used for resolving dampness, stimulating appetite, inducing resuscitation, eliminating phlegm, refreshing mind and improving intelligence. Can be used for treating epigastric fullness, inappetence, dysentery, coma, epilepsy, amnesia, and deafness.
Pearl, sweet, salty and cold; heart and liver meridian entered; it is mainly used for tranquilizing and arresting convulsion, improving eyesight and removing nebula, detoxicating and promoting granulation. Can be used for treating palpitation, insomnia, infantile convulsion, epilepsy, nebula, eye cloudiness, and unhealing sore and ulcer.
Coptis root, bitter and cold; the channels of heart, spleen, stomach, liver, gallbladder and large intestine; it is mainly used for clearing heat and drying dampness, purging fire and removing toxicity. Can be used for treating damp-heat distention, fullness, emesis, acid regurgitation, dysentery, jaundice, hyperpyrexia, coma, excessive heart-fire, vexation, insomnia, hematemesis, hemorrhage, conjunctival congestion, toothache, diabetes, carbuncle, furuncle, etc.; it is used externally to treat eczema, eczema and purulent ear canal. Huang Lian (Chinese goldthread) processed with wine is good at clearing heat in upper energizer. It can be used for treating conjunctival congestion and aphtha. Jiang Huang Lian can clear stomach, harmonize stomach and stop vomiting. Can be used for treating cold and heat accumulation, damp-heat obstruction, fullness and emesis. Yu Huang Lian soothes liver, harmonizes stomach and stops vomiting. Can be used for treating liver and stomach disharmony, emesis and acid regurgitation.
Poria cocos, sweet, bland and flat; the heart, lung, spleen and kidney meridians are entered; the main treatment is diuresis inducing, dampness eliminating, spleen strengthening and heart calming. Can be used for treating edema, oliguria, phlegm and fluid retention, dizziness, palpitation, spleen deficiency, anorexia, loose stool, diarrhea, uneasiness, palpitation, and insomnia.
The invention has the beneficial effects that:
1. the eye protection liquid disclosed by the invention adopts natural traditional Chinese medicine raw materials, is safe and has no toxic or side effect, and retains bioactive components in the raw materials to the maximum extent through advanced processes such as strict screening, PBS (phosphate buffer solution) solution extraction or ethanol extraction, vacuum concentration and the like, and is reasonably matched, so that a finished product achieves a better eye protection effect;
2. the eye protection liquid disclosed by the invention is mainly antibacterial and bacteriostatic, has the effects of improving eyesight and nebula, inducing resuscitation and refreshing mind, has the effects of diminishing inflammation, repairing and improving immunity, has a conditioning effect on relieving eye fatigue, eye dryness and tearing against wind, and can improve the prevention capability of eye diseases.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the technical solutions of the present invention will be described in detail below. It is to be understood that the described embodiments are merely exemplary of the invention, and not restrictive of the full scope of the invention. All other embodiments, which can be derived by a person skilled in the art from the examples given herein without any inventive step, are within the scope of the present invention.
In some more specific embodiments, the eye-protecting solution is prepared from the following raw materials in parts by weight: the eye protection solution is prepared from the following raw materials in parts by weight: 4-6 parts of ginseng, 1-3 parts of mulberry leaf, 1-3 parts of angelica dahurica, 2-4 parts of salvia miltiorrhiza, 2-4 parts of rhizoma acori graminei, 4-6 parts of pearl, 4-6 parts of abalone shell, 1-3 parts of coptis chinensis, 1-3 parts of angelica sinensis, 2-5 parts of wolfberry fruit and 4-8 parts of poria cocos.
The preparation method of the eye-protecting liquid comprises the following steps:
(1) weighing mulberry leaves, angelica dahurica, rhizoma acori graminei, concha haliotidis, coptis chinensis, angelica sinensis, wolfberry fruits and poria cocos according to a proportion, respectively crushing, then mixing, and uniformly mixing to form a material to be extracted;
(2) adding distilled water and a PBS solution into the material to be extracted obtained in the step (1), soaking for 3-5 hours, then decocting for 35-45 minutes with slow fire for the first time, filtering, and collecting the first filtrate; adding distilled water and PBS solution into the filter residue, decocting with slow fire for 35-45 min for the second time, filtering, and collecting the second filtrate; combining the first filtrate and the second filtrate to form an extract;
(3) weighing ginseng and salvia miltiorrhiza according to a proportion, respectively crushing to 100-200 meshes, then mixing, uniformly mixing to form a material to be extracted, soaking the material to be extracted for 10-14 hours by using 60-90% ethanol as a solvent, filtering, collecting filtrate, recovering ethanol, concentrating into paste, vacuum drying, crushing to form two mixed powders of ginseng and salvia miltiorrhiza;
(4) and (3) adding the two mixed powders obtained in the step (3) and pearls into the extracting solution obtained in the step (2), uniformly mixing, concentrating at 60-70 ℃, filtering again, sterilizing, cooling and subpackaging to obtain the eye-protecting liquid.
Example 1
The embodiment provides an eye-protecting solution, which is prepared from the following raw materials:
6g of ginseng, 1g of mulberry leaf, 3g of angelica dahurica, 2g of salvia miltiorrhiza, 4g of rhizoma acori graminei, 4g of pearl, 6g of abalone shell, 1g of coptis chinensis, 3g of angelica sinensis, 2g of wolfberry fruit and 8g of poria cocos;
the preparation method of the eye-protecting liquid comprises the following steps:
(1) weighing folium Mori, radix Angelicae Dahuricae, rhizoma Acori Graminei, Concha Haliotidis, Coptidis rhizoma, radix Angelicae sinensis, fructus Lycii and Poria in proportion, respectively pulverizing to 80-100 mesh, mixing, and mixing to obtain the material to be extracted;
(2) adding distilled water and a PBS solution into the material to be extracted obtained in the step (1), soaking for 5 hours, then decocting for 45 minutes with slow fire for the first time, filtering, and collecting the first filtrate; adding distilled water 6 times the weight of the filter residue and PBS solution with pH of 7.4 into the filter residue, decocting with slow fire for 45 min for the second time, filtering, and collecting the second filtrate; combining the first filtrate and the second filtrate to form an extract; the adding amount ratio of the distilled water to the PBS solution is 1:1, and the temperature of slow fire is 65-75 ℃;
(3) weighing ginseng and salvia miltiorrhiza according to a proportion, respectively crushing to 100-200 meshes, then mixing, uniformly mixing to form a material to be extracted, soaking the material to be extracted for 10 hours by using 60% ethanol as a solvent, filtering, collecting filtrate, recovering ethanol, concentrating into paste, drying in vacuum, crushing to form two mixed powders of ginseng and salvia miltiorrhiza;
(4) adding the two mixed powders obtained in the step (3) and pearls into the extracting solution obtained in the step (2), uniformly mixing to form a material to be concentrated, concentrating at 60-70 ℃ until the mass of the material to be concentrated is 60% of that of the material to be concentrated, filtering with a 400-mesh sieve again, sterilizing with high-pressure steam, cooling, and subpackaging to obtain the eye-protecting liquid.
Example 2
The embodiment provides an eye-protecting solution, which is prepared from the following raw materials:
4g of ginseng, 3g of mulberry leaf, 1g of angelica dahurica, 4g of salvia miltiorrhiza, 2g of rhizoma acori graminei, 6g of pearl, 4g of abalone shell, 3g of coptis chinensis, 1g of angelica sinensis, 5g of wolfberry fruit and 4g of poria cocos; the pearl is pearl powder, and the particle fineness of the pearl powder is 100-200 meshes;
the preparation method of the eye-protecting liquid comprises the following steps:
(1) weighing folium Mori, radix Angelicae Dahuricae, rhizoma Acori Graminei, Concha Haliotidis, Coptidis rhizoma, radix Angelicae sinensis, fructus Lycii and Poria in proportion, respectively pulverizing to 80-100 mesh, mixing, and mixing to obtain the material to be extracted;
(2) adding distilled water and a PBS solution into the material to be extracted obtained in the step (1), soaking for 3 hours, then decocting for 35 minutes with slow fire for the first time, filtering, and collecting the first filtrate; adding distilled water with the weight 10 times of that of the filter residue and PBS (phosphate buffer solution) with the pH value of 7.4 into the filter residue, decocting for 35 minutes with slow fire for the second time, filtering, and collecting the second filtrate; combining the first filtrate and the second filtrate to form an extract; the adding amount ratio of the distilled water to the PBS solution is 1:1, and the temperature of slow fire is 65-75 ℃;
(3) weighing ginseng and salvia miltiorrhiza according to a proportion, respectively crushing to 100-200 meshes, then mixing, uniformly mixing to form a material to be extracted, soaking the material to be extracted for 14 hours by using 90% ethanol as a solvent, filtering, collecting filtrate, recovering ethanol, concentrating into paste, drying in vacuum, crushing to form two mixed powders of ginseng and salvia miltiorrhiza;
(4) adding the two mixed powders obtained in the step (3) and pearls into the extracting solution obtained in the step (2), uniformly mixing to form a material to be concentrated, concentrating at 60-70 ℃ until the mass of the material to be concentrated is 60% of that of the material to be concentrated, filtering with a 400-mesh sieve again, sterilizing with high-pressure steam, cooling, and subpackaging to obtain the eye-protecting liquid.
Example 3
The embodiment provides an eye-protecting solution, which is prepared from the following raw materials:
5g of ginseng, 2g of mulberry leaf, 2g of angelica dahurica, 3g of salvia miltiorrhiza, 3g of rhizoma acori graminei, 5g of pearl, 5g of concha haliotidis, 2g of coptis chinensis, 2g of angelica sinensis, 3g of wolfberry fruit and 6g of poria cocos;
the preparation method of the eye-protecting liquid comprises the following steps:
(1) weighing folium Mori, radix Angelicae Dahuricae, rhizoma Acori Graminei, Concha Haliotidis, Coptidis rhizoma, radix Angelicae sinensis, fructus Lycii and Poria in proportion, respectively pulverizing to 80-100 mesh, mixing, and mixing to obtain the material to be extracted;
(2) adding distilled water and a PBS solution into the material to be extracted obtained in the step (1), soaking for 4 hours, then decocting for 40 minutes with slow fire for the first time, filtering, and collecting the first filtrate; adding distilled water with the weight 8 times of that of the filter residue and PBS (phosphate buffer solution) with the pH value of 7.4 into the filter residue, decocting for 40 minutes with slow fire for the second time, filtering, and collecting the second filtrate; combining the first filtrate and the second filtrate to form an extract; the adding amount ratio of the distilled water to the PBS solution is 1:1, and the temperature of slow fire is 65-75 ℃;
(3) weighing ginseng and salvia miltiorrhiza according to a proportion, respectively crushing to 100-200 meshes, then mixing, uniformly mixing to form a material to be extracted, soaking the material to be extracted for 12 hours by using 85% ethanol as a solvent, filtering, collecting filtrate, recovering ethanol, concentrating into paste, drying in vacuum, crushing to form two mixed powders of ginseng and salvia miltiorrhiza;
(4) adding the two mixed powders obtained in the step (3) and pearls into the extracting solution obtained in the step (2), uniformly mixing to form a material to be concentrated, concentrating at 60-70 ℃ until the mass of the material to be concentrated is 60% of that of the material to be concentrated, filtering with a 400-mesh sieve again, sterilizing with high-pressure steam, cooling, and subpackaging to obtain the eye-protecting liquid.
The above description is only for the specific embodiments of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art can easily conceive of the changes or substitutions within the technical scope of the present invention, and all the changes or substitutions should be covered within the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the appended claims.
Claims (10)
1. The eye-protecting solution is characterized by being prepared from the following raw materials: ginseng, mulberry leaf, angelica dahurica, salvia miltiorrhiza, grassleaf sweelflag rhizome, pearl, abalone shell, coptis chinensis, angelica, medlar and tuckahoe.
2. The eye-protecting solution according to claim 1, wherein the eye-protecting solution is prepared from the following raw materials in parts by weight: the eye protection solution is prepared from the following raw materials in parts by weight: 4-6 parts of ginseng, 1-3 parts of mulberry leaf, 1-3 parts of angelica dahurica, 2-4 parts of salvia miltiorrhiza, 2-4 parts of rhizoma acori graminei, 4-6 parts of pearl, 4-6 parts of abalone shell, 1-3 parts of coptis chinensis, 1-3 parts of angelica sinensis, 2-5 parts of wolfberry fruit and 4-8 parts of poria cocos.
3. The eye-protecting solution according to claim 2, wherein the eye-protecting solution is prepared from the following raw materials in parts by weight: 5 parts of ginseng, 2 parts of mulberry leaf, 2 parts of angelica dahurica, 3 parts of salvia miltiorrhiza, 3 parts of grassleaf sweelflag rhizome, 5 parts of pearl, 5 parts of abalone shell, 2 parts of coptis chinensis, 2 parts of angelica, 3 parts of medlar and 6 parts of tuckahoe.
4. The eye-protecting solution according to claims 1-3, wherein the pearl is pearl powder, and the particle fineness of the pearl powder is 100-200 meshes.
5. The method of preparing eye-care solution according to any one of claims 1 to 4, comprising the steps of:
(1) weighing mulberry leaves, angelica dahurica, rhizoma acori graminei, concha haliotidis, coptis chinensis, angelica sinensis, wolfberry fruits and poria cocos according to a proportion, respectively crushing, then mixing, and uniformly mixing to form a material to be extracted;
(2) adding distilled water and a PBS solution into the material to be extracted obtained in the step (1), soaking for 3-5 hours, then decocting for 35-45 minutes with slow fire for the first time, filtering, and collecting the first filtrate; adding distilled water and PBS solution into the filter residue, decocting with slow fire for 35-45 min for the second time, filtering, and collecting the second filtrate; combining the first filtrate and the second filtrate to form an extract;
(3) weighing ginseng and salvia miltiorrhiza according to a proportion, respectively crushing to 100-200 meshes, then mixing, uniformly mixing to form a material to be extracted, soaking the material to be extracted for 10-14 hours by using 60-90% ethanol as a solvent, filtering, collecting filtrate, recovering ethanol, concentrating into paste, vacuum drying, crushing to form two mixed powders of ginseng and salvia miltiorrhiza;
(4) and (3) adding the two mixed powders obtained in the step (3) and pearls into the extracting solution obtained in the step (2), uniformly mixing, concentrating, filtering again, sterilizing, cooling and subpackaging to obtain the eye protection solution.
6. The method for preparing eye-protecting liquid according to claim 7, wherein in the step (1), the fineness of the crushed particles is 80-100 meshes.
7. The method of claim 7, wherein the ratio of the distilled water to the PBS solution in step (2) is 1:1.
8. The method of claim 7, wherein the mild fire is at a temperature of 65-75 ℃ in step (2).
9. The method for preparing eye-protecting liquid according to claim 7, wherein in the step (4), the pearl is added into the extracting solution, the pearl and the extracting solution are uniformly mixed to form a material to be concentrated, and the material to be concentrated is concentrated at 60-70 ℃ until the mass of the material to be concentrated is 60%; the sterilization adopts high-pressure steam sterilization.
10. The method of claim 7, wherein the filtration is 400 mesh.
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| CN113384614A (en) * | 2021-07-25 | 2021-09-14 | 北京阅亮科技有限公司 | Preparation method of eye care solution |
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