CN106333916A - Scalp nourishing liquid for treating alopecia and promoting hair growth - Google Patents

Scalp nourishing liquid for treating alopecia and promoting hair growth Download PDF

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Publication number
CN106333916A
CN106333916A CN201610814302.1A CN201610814302A CN106333916A CN 106333916 A CN106333916 A CN 106333916A CN 201610814302 A CN201610814302 A CN 201610814302A CN 106333916 A CN106333916 A CN 106333916A
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weight
nourishing liquid
extract
hair
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CN106333916B (en
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赵文忠
陈贤鹰
林学镁
洪盛杰
谷志静
周起
董志扬
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LAF INTERNATIONAL GROUP Ltd
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LAF INTERNATIONAL GROUP Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/002Preparations for repairing the hair, e.g. hair cure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/12Preparations containing hair conditioners

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
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  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
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  • Microbiology (AREA)
  • Mycology (AREA)
  • Cosmetics (AREA)

Abstract

The invention belongs to the field of daily use chemicals, and particularly relates to scalp nourishing liquid. The scalp nourishing liquid comprises (A) a humulus lupulus extract with the weight of 1 to 5 percent of that of the nourishing liquid, (B) a rosemary extract with the weight of 0.1 to 2 percent of that of the nourishing liquid, (C) a false chinese swertia herb extract with the weight of 0.05 to 2 percent of that of the nourishing liquid, (D) an auxiliary active ingredient with the weight of 0.0075 to 0.15 percent of that of the nourishing liquid, and (E) a cosmetically acceptable carrier, wherein the auxiliary active ingredient is an artemia extract. The scalp nourishing liquid has the characteristics that four active ingredients in the nourishing liquid achieve a synergistic effect with one another; the scalp nourishing liquid prevents and lightens hair loss, fights against androgen alopecia, prevents complete atrophy of hair follicles, and promotes the growth of new hair.

Description

A kind of scalp tonic liquid processing alopecia and promoting natural on-off cycles of hair growth
Technical field
The invention belongs to household chemicals field is and in particular to a kind of scalp tonic liquid, this scalp tonic liquid has process alopecia and rush Enter the function of natural on-off cycles of hair growth.
Background technology
Alopecia vernacular is bald head, and stricti jurise can not be referred to as a kind of illness, and more belongs to a kind of biological function Disorder, the psychology that can give people brings impact.The relatively common androgenalopecia that has is that man is common.
The quantity having data statisticss man's hair averagely between 100,000 to 150,000, the quantity of daily alopecia between Normal range is belonged between 80 to 100.However, in order to prevent the generation of alopecia to keep the par of hair, That is the cycle that a kind of normal life and death of every hair of holding substitutes is extremely important.
According to document, the most common are androgenetic alopecia in various alopecias and cause, be that a kind of gonadal hormone stimulates initiation Hair follicle changes and is affected and cause alopecia by genetic factor and aging action.The alopecia mistake being caused by gonadal hormone Cheng Zhong, testosterone is this to play key player by the androgen that genitals produce.But known 50% circulation testosterone is Produced by perienchyma.In hair follicle, a kind of 5-a- reductase (being also testosterone reductase), testosterone can be converted into dihydro-testosterone Ketone (dht), the activity of dihydrotestosterone is more higher than testosterone and gathers the function of reducing hair follicle in hair follicle cell film thus stoping head The growth sent out.
In addition, being reported according to pertinent literature, the alopecia of head potential head skin is associated with gonadal hormone with other body parts Degree differs.In other words, the secretion of adolescence initial stage androgen is conducive to the growth (example of the hair of body part on the contrary As beard, chesk hair, oxter hair, breech etc.), and meanwhile the natural on-off cycles of hair growth at crown position will be suppressed.This situation Generation may be relevant with genetic diversity.
For women, because the estrogen (female sex hormone) of a large amount of secretions inhibits the performance of male hormone, offset Generation because of the baldness phenomenon that male hormone leads to.But with involutional arrival, the female He Er corresponding to women The secretion covered constantly reduces, and meanwhile circulates testosterone and constantly get the upper hand, and has then caused as male pattern baldness Semiotics phenomenon.
Explain that after male menopause, depilation phenomenon there is presently no enough evidence supports with hormone method.
Occur the first tissue change in hair follicle connective tissue to show as degenerative focus, and lead to thermophilic around blood vessel The change of alkalescence.Even scalp sites hair follicle starts to shrink at and therefore produces very little hair, but still has a small part quiet The hair follicle of state end can be with stimulating growth.
Except prohormone because in addition to, other factors causing alopecias include: lack nursing and caused due to outside invasion Hair follicle cell aging;Because the reduction of scalp microcirculation function causes the disappearance of hair nutrition;Hair cell proliferation is very slow Slowly.Hair aging course along with people as skin, the aging of hair includes the aging of dry aging and hair follicle, two kinds Degeneracy drops and comes off along with hair.As a rule, dry aging easy initiation hair shaft is fragile or fractures, hair follicle Aging initiation alopecia.Dry aging mainly caused by extrinsic factor, it is mainly shown as: sends out tip jag, lacks Gloss, withered and yellow, coarse, dry and be difficult to combing etc..Dry aging main by extrinsic factor cause as, illumination, wind, rain, The chemical substance of air pollution, sea water or swimming pool, and hair blowing hot wind, stretch and physical factor and the hair such as excessive combing The chemical factor such as drift, have hair dyed and perm.The aging of hair follicle is mainly caused by endogenous factor, such as in human body natural's ageing process The excessive free radicals that the reasons such as radical scavenging activity decline, organism endocrine imbalance and immunologic function degression produce, also lose Biography factor and nutrient substance lack etc., and in addition also depressed, pressure is excessive and Nervous and Mental Factors and the life side such as psychentonia The factors such as formula.Hair follicle aging be mainly manifested in hair bleach, attenuate, hair follicle reduce and alopecia, alopecia etc..
All the time, improving and social development with people's living standard, people increasingly focus on personal image Build, personal image role in social life and work also more comes important.Therefore, many cosmetics are looked forward to all the time Industry always works on the research and development of hair nursing and scalp care cosmetics it is desirable to produce the product reducing alopecia simultaneously right Natural on-off cycles of hair growth is promoted to have good effect.
Content of the invention
Invention technician, on the basis of for causing alopecia reason, is prepared according to different ratio and is obtained A kind of scalp tonic liquid, this nourishing liquid has the auxiliary activity thing adjusting natural on-off cycles of hair growth function.
The scalp tonic liquid that the present invention processes alopecia and promotes natural on-off cycles of hair growth, includes:
A () accounts for the Flos lupuli (Flos Humuli Lupuli) extract of nourishing liquid weight 1-5%;
B () accounts for the Herba Rosmarini Officinalis extract of nourishing liquid weight 0.1-2%;
C () accounts for the Herba Swertiae bimaculatae extract of nourishing liquid weight 0.05-2%;
D () accounts for the auxiliary activity composition of nourishing liquid weight 0.0075-0.15%, this auxiliary activity composition extracts for artemia Thing;
(e) cosmetically acceptable carrier:
Account for the ethanol of nourishing liquid weight 8-35%;
Account for the Polyoxyl 40 Hydrogenated Castor Oil of nourishing liquid weight 0.05-3%;
Account for the d- pantothenylol of nourishing liquid weight 0.05-2%;
Appropriate preservative, essence, the deionized water of pigment, ph regulator and surplus.
Scalp tonic liquid of the present invention, wherein Flos lupuli (Flos Humuli Lupuli) extract account for nourishing liquid percentage by weight 1.5-3%;Herba Rosmarini Officinalis extracts Thing accounts for nourishing liquid percentage by weight 0.5-1%;Herba Swertiae bimaculatae extract accounts for nourishing liquid percentage by weight 0.1-0.8%;Artemia extracts Thing accounts for nourishing liquid percentage by weight 0.03-0.075%.
Scalp tonic liquid of the present invention, wherein in cosmetically acceptable carrier, ethanol accounts for nourishing liquid percentage by weight 23- 29%, Polyoxyl 40 Hydrogenated Castor Oil accounts for nourishing liquid percentage by weight 0.1-1.5%, and d- pantothenylol accounts for nourishing liquid weight of the present invention Percentage ratio is 0.1-1%.
The present composition, in addition to above four kinds of active ingredients, also comprises the acceptable one-tenth of present composition cosmetics Part such as ethanol, water alcohol medium and other formula auxiliary ingredients such as vitamin, pigment, essence etc..
Advantages of the present invention:
Alopecia is the result of an extremely complex physiological process.The present invention three Plant Extracts are extracted with a kind of artemia The scientific matching of thing has collaborative Anti-hair loss effect, from preventing and treating, nourishes and protects, the stage construction such as treatment considers such as head Skin antioxidation, suppression 5-a- reductase activity and then suppression cause the generation of the dihydrotestosterone (dht) of baldness, promote keratinization thin The increment of born of the same parents, stimulates and activation hair follicle, many active factors such as energy supplement of scalp and hair follicle start with, prevent and Mitigate alopecia, resist androgenetic alopecia, prevent the complete atrophy of hair follicle, and new life goes out hair.Effect is passed through Clinical volunteers clinical testing data proves.
Brief description
Fig. 1 is sending out situation map for volunteer using product front of the present invention;
Fig. 2 is sending out situation map for same volunteer using 90 days back of product of the present invention.
Specific embodiment
Rosmarinuss Labiatae shrub adornment plant, high more than 1 meter, evergreen shrubss, strain is upright, and leaf is grayish green, narrow apicule shape, blade Dissipate pinaster fragrance, be considered from ancient times can hypermnesis medicinal herbs.Its flower is white or light green color.With Herba Rosmarini Officinalis in the present invention Leaf is that crude drug extracts, and takes Herba Rosmarini Officinalis cured leaf, and for 7% to 10%, solvent is that the ethanol water of weight 50% is carried to weight ratio Take (extraction), after 24 hours, be filtered into Herba Rosmarini Officinalis extract.Rosemary contains antioxidant, main component It is that there is the phenol of anti-oxidation function, acid, flavones ingredient;Rosemary ethereal oil is then a kind of to be made up of more than 30 kinds of volatile ingredients Liquid oily thing.Herba Rosmarini Officinalis extract has efficient, nontoxic antioxidant effect, can be widely applied to food, functional food, perfume (or spice) In material and the industry such as flavoring agent and daily-use chemical industry.Essence etc..Many documents and the biological of research Herba Rosmarini Officinalis extract all on the books are lived Property and alopecia treatment effectively (1) Herba Rosmarini Officinalis extract had comprise cell membrane, participate in neutralization tissue oxidation reaction from By base, (2) suppression causes the generation of the dihydrotestosterone (dht) of baldness.
Flos lupuli (Flos Humuli Lupuli) is Cannabaceae, grass belongs to, perennial herb trailing plant, climing long more than the 6m of Flos lupuli (Flos Humuli Lupuli), and the close life of entire body is thin Hair, and have agnail.Leaf opposite, papery, avette or palm shape, 3-5 splits, and has rough sawn tooth.Originate in Europe, America and Asia.Can be used for Beer brewing and medicinal.Flos lupuli (Flos Humuli Lupuli) is resinous, wherein has oxadiazon, different oxadiazon .beta.-bitter acid etc.;Containing volatile oil, wherein there is perfume (or spice) Leaf alkene, oxalene, linalool, Fols lupuli alcohol etc..Additionally, still having tannin, chromocor compound, choline, Fructose, sucrose, glucose etc.. Hop raw material and the place of production with natural hops or hop pellets, compression Flos lupuli (Flos Humuli Lupuli) as raw material, Xinjiang, China real estate.Production technology will After hop material is pulverized, produced using liquid co2 abstraction technique.Hop extraction physical property shape is golden yellow extremely amber sticky Liquid, has typical Flos lupuli (Flos Humuli Lupuli) fragrance.The main component of main component this product is alpha-acid, β-acid etc..Alpha-acid: 45% ± 2% β-acid: > 15 moisture :≤1.0%, product feature 100% pure natural Flos lupuli (Flos Humuli Lupuli) extract, no molten residual and chemical addition agent.Entirely Technical process is being carried out under normal temperature condition, and product completely remains feature and the fragrance of natural hops, and it act as (1) suppression The activity of 5-a- reductase processed, thus suppress the generation of dihydrotestosterone (dht);(2) the value-added catalyst of a kind of keratinocyte, (3) a kind of antioxidant of anti-peroxidation reaction, but its antioxygenic activity is slightly below Herba Rosmarini Officinalis.
Swertia plant, annual herb, high 10-40 centimetre.Stem is single or branch, four prismatics, carries purple.Leaf pair Raw, stockless, wire lanceolar, long 2-4 centimetre, tip is tapering, and base portion is narrow, full edge.Chemical analysis are to work as medicine, containing swertiamarin about 2-4%, also contains swertisin, gentisin, gentisin glucoside etc..Double speckle Herba Swertiae bimaculataes contain isovitexin, different Orientin;Also dihydroxy -4 containing 1,3-, the 1-o- β-d- Glucopyranose. of 5- dimethoxy xanthone and this xanthone Glycoside and 3- ο-β-d glucopyanoside;Contain swertiamarin and sweroside again.When the swertiamarin separating in medicine, through skin surface It is easy to absorb, decomposes after absorption, generate 5-formyl-3,4-dihydro-1H-2-benzopyran-1-one., expansible blood capillary, and activate or promote the enzyme of Skin Cell System, improves the biochemical function of skin histology.In the present invention, Herba Swertiae bimaculatae follows the example of extraction using alcohol extraction, and main active ingredient is river deer tooth Dish hardship glycosides, in extract, the content of swertiamarin is not less than weight and compares 3%.Document shows, Herba Swertiae bimaculatae plant is wide in Japan General accept and be used for for oral administration and external, for processing various illness, Japanese s.utsunomiya, t.ni shiura and The research of y.hagihara Tokushima University Dermatology system shows, Herba Swertiae bimaculatae extract provides oxygen part and nutrition to hair follicle tissue, because This can directly stimulate, activate hair follicle, promote the blood circulation of hair root, and activation hair cell simultaneously and then is converted into promotion The growth power of hair.
Auxiliary activity composition
Auxiliary activity composition of the present invention combines Ya Shilan company of U.S. biothairapytmHair care based on biotechnology Research/development platform: i.e. 1, the unique research/development platform based on ex vivo supravital scalp hair follicles tissue slice investigative technique ability;2、 Concern root of hair health degree is thus provide long-acting aesthetic effect;3rd, the Biofunctional raw material of innovation is absorbed in scalp, hair follicle The related key organism label of health.
Auxiliary activity composition of the present invention is to adjust composition such as selected from the natural on-off cycles of hair growth of Ya Shilan (arshland) company, a kind of Corn extract capauxeintmBiofunct ional, inci name: water (and) glycerol (and) hydrolysed corn albumen, this jade Rice extracts are by controlling hair density, the crucial biomarker of linking up of richness excites inspiration;A kind of rice extract dynagentmBiofunct ional, inci name: water (and) glycerol (and) hydrolyzed yeast albumen;A kind of rice protein, protectagentmBiofunct ional, inci name: water (and) glycerol (and) hydrolysed rice albumen, Inspiration Sources are in ' head Dry cell system ' a kind of rice extract, help ease off the pressure and protect natural on-off cycles of hair growth;A kind of artemia extract gp4g Sp biofunct ional, consisting of, artemia extract, phenoxyethanol, potassium sorbate, water, wherein: water: 97.366%, Artemia extract artemia extract:1.5%, phenoxyethanol: 1.0% 3 potassium sorbate: 0.134%, artemia therein extracts Thing artemia extract is active ingredient.Artemia is also referred to as saline fairy shrimp.Folks of china is also referred to as salt insect or shrimps, point Arthropoda, Branchiata, Crustachia, Branchiopoda, Anostraca, saline fairy shrimp section, genus artemia are belonged on class (artemia) artemia, as a kind of good laboratory animal material of important food organisms section, is constantly subjected to the extensive weight of people Depending on.Artemia extract is a kind of plankton extractions, has superpower effect of energizing, rich in nucleotide, is proven to have and is directed to The effect of ambient pressure environment (including photoaging and the aging pressure of ambient temperature) effective protection, moisturizing effects, because contained egg White matter and other moisturizing composition combine and so that scalp is kept certain humidity and prevent from being dehydrated.
More both effectiveness test confirm artemia extract for adjust with the related cellular stress factor of sensitivity have very strong Effect, thus playing effect of calm scalp, recent studies have shown that artemia extract during hair restoration Effectively adjustment effect (j.cosmet.sci., 62,469 482september/october 2011).Auxiliary activity of the present invention becomes Part preferably artemia (artemia) extract, artemia (artemia) extract of the present invention refers to Ya Shilan trade name gp4g Artemia active ingredient in spbiofunctional, artemia extract accounts for scalp tonic liquid percentage by weight of the present invention 0.0075% to 0.15%, optimize further and be weight percentage 0.03% to 0.075%.
Cosmetically acceptable carrier: the present invention also comprises cosmetically acceptable carrier such as, and solvent adopts dehydrated alcohol With the mixed solution of deionized water, wherein dehydrated alcohol accounts for nourishing liquid percentage by weight 8-35% of the present invention, one-step optimization of going forward side by side For 23-29%;Wetting agent adopts glycerol, propylene glycol, 1.3 butanediols and d- pantothenylol, the present invention preferred d- pantothenylol, and d- pantothenylol accounts for this Invention nourishing liquid percentage by weight is 0.05-2%, is optimized for 0.1-1% further;Account for percentage by weight 0.05-3% of the present invention Polyoxyl 40 Hydrogenated Castor Oil, and optimize the Polyoxyl 40 Hydrogenated Castor Oil of the 0.1-1.5% that is weight percentage;In right amount Preservative, essence, pigment, ph regulator, have nursing role composition such as have skin protection or hair care effect plant extract Thing, hydrolytic collagen, fibroin, lanolin derivative;Bright protective agent, antioxidant, free radical scavenger;Hair brightener, Vitamin etc..
Scalp tonic liquid of the present invention comprises using method such as, takes the hair nutrition liquid of q.s and on scalp, and uses handss Finger belly is gently patted and is massaged until absorbing.
The present invention three Plant Extracts and a kind of combination of artemia extract are particularly suitable for protective agent and the head of hair There is long accelerator, and be applied to hair articles for use as active component and obtain nourishing and protected effect, thus preferably right Androgen antagonist alopecia.Alopecia therefore can be mitigated, prevent the complete atrophy of hair follicle, and new life goes out hair.Effect Fruit is proved by clinical volunteers clinical testing data.
From quantitative angle, the composition components of hair nourishing liquid of the present invention are as follows:
Three extracts and auxiliary activity composition composition account for nourishing liquid percentage by weight of the present invention be 1.1575% to 9.15%.Remaining composition is 90.8%% to 98.8%.
Four kinds of active substances meet following ratio:
H > r > sw > coa
Wherein: h- Flos lupuli (Flos Humuli Lupuli) extract percentage by weight, r- Herba Rosmarini Officinalis extract percentage by weight, sw- Herba Swertiae bimaculatae extracts Thing percentage by weight, coa auxiliary activity Ingredient Wt percentage ratio.
Four kinds of active matters, every kind of to account for nourishing liquid percentage by weight of the present invention as follows
H- Flos lupuli (Flos Humuli Lupuli) extract accounts for nourishing liquid percentage by weight 1-5% of the present invention,
R- Herba Rosmarini Officinalis extract accounts for nourishing liquid percentage by weight 0.1-2% of the present invention
Sw- Herba Swertiae bimaculatae extract accounts for nourishing liquid percentage by weight 0.05-2% ratio of the present invention
Coa- auxiliary activity composition, artemia extract accounts for nourishing liquid percentage by weight 0.0075-0.15% of the present invention
Four kinds of active matters, every kind of account for nourishing liquid percentage by weight of the present invention and are optimized for further:
H- Flos lupuli (Flos Humuli Lupuli) extract accounts for nourishing liquid percentage by weight 1.5-3% of the present invention,
R- Herba Rosmarini Officinalis extract accounts for nourishing liquid percentage by weight 0.5-1% of the present invention
Sw- Herba Swertiae bimaculatae extract accounts for nourishing liquid percentage by weight 0.1-0.8% of the present invention,
Coa- auxiliary activity composition, artemia extract accounts for nourishing liquid percentage by weight 0.03-0.075% of the present invention
It is below the embodiment of scalp tonic liquid of the present invention:
Embodiment
The non-limiting example of of the present invention scalp tonic liquid is presented herein below.Being only given to illustrate of these embodiments Purpose, can not be interpreted as limitation of the invention, because without departing from the spirit and scope of the present invention, can be right The present invention carries out many changes.In these embodiments, unless stated otherwise, all of concentration is all percentage by weight.
Embodiment-
Embodiment-
Highly preferred embodiment of the present invention is:
Component Weight (%)
Dehydrated alcohol 28.0
Polyoxyl 40 Hydrogenated Castor Oil 1.4
Flos lupuli (Flos Humuli Lupuli) extract 2.8
Herba Rosmarini Officinalis extract 0.9
Herba Swertiae bimaculatae extract 0.7
Artemia extract 0.07
D- pantothenylol 0.95
Preservative, essence, pigment, ph regulator In right amount
Deionized water Add to 100%
The checking of Anti-hair loss effect
Using method: the daily usage amount arranging about 6 milliliters of nourishing liquids of an ampulla, adhere to using an ampulla daily, use Before hair nourishing liquid of the present invention with using during hair nourishing liquid of the present invention, have one's hair wash 2-3 time weekly, had one's hair wash using faintly acid fragrant Ripple has one's hair wash (ph value 5.5);Wipe hair with towel after hair washing, by the nourishing liquid in ampulla be applied on hair and and gently by Rub scalp 1 minute, and after hair washing, hair is under leather hard using optimal.
Method of testing: select 60 volunteers having alopecia it is desirable to no allergy, no wound, unsystematic local disease Scalp health person, by image viewing, the trophophase of volunteer's hair and resting stage ratio are less than normal condition, are divided into 4 groups, point The embodiment of the present invention (first group), (second group), contrast 1 (the 3rd group) and contrast 2 (the 4th groups) Dui Ying not used.Continue Using 90 days, and carry out sensory evaluation and hair image evaluation using 45 days with using 90 days respectively.For using the present invention Before and after scalp tonic liquid, Tables 1 and 2 is shown in the photosensitive assessment of volunteer's Anti-hair loss.
Table 1
By table 1, the embodiment of the present invention (first group), the embodiment of the present invention (second group), present invention contrast 1 (the Three groups) and the present invention contrast 2 (the 4th groups), persistently using 90 days, and respectively using 45 days with carried out sense organ using 90 days and comment Estimate result to show: the embodiment of the present invention (first group) and the embodiment of the present invention (second group) contrast 1 the (the 3rd with the present invention Group) and (the 4th group) contrast of present invention contrast 2, reduces first group and second group of the percentage ratio of hair alopecia amount apparently higher than the 3rd With the 4th group, illustrate the present invention " a kind of process alopecia and promote natural on-off cycles of hair growth scalp tonic liquid " there is good hair anticreep Effect;Found by the 3rd group and the 4th group of Data Comparison: the 4th group is that the embodiment of present invention contrast 2 takes off for reducing hair The percentage ratio (during combing, during hair washing, during sleep) falling is all higher than the embodiment of present invention contrast 1, illustrates to contrast the hair life in 2 Long regulatory factor, the interpolation of artemia extract has certain effect to hair anticreep and hair strengthening tool.
Table 2
By table 2, the embodiment of the present invention (first group), the embodiment of the present invention (second group), present invention contrast 1 (the Three groups) and the present invention contrast 2 (the 4th groups), persistently using 90 days, and respectively using 45 days and using 90 days to natural on-off cycles of hair growth Improvement be estimated showing: the embodiment of the present invention (first group) and the embodiment of the present invention (second group) and present invention contrast 1 (the 3rd group) and (the 4th group) contrast of present invention contrast 2, promote first group and second group of the percentage ratio of natural on-off cycles of hair growth apparently higher than Third and fourth group, illustrate that the present invention " a kind of process alopecia and the scalp tonic liquid promoting natural on-off cycles of hair growth " has good anticreep With the effect promoting natural on-off cycles of hair growth, after wherein having extraordinary experimenter to use 90 days, originally overgrowed with thin on rare hair Little fine hair, is shown in Fig. 1, Fig. 2 respectively.This is that hair is returned to the distinctive markss of trophophase from resting stage.
Found by the 3rd group and the 4th group of Data Comparison: the 4th group is the embodiment of present invention contrast 2 for promotion head Occur long percentage ratio to be more than the embodiment of present invention contrast 1, illustrate to contrast the active ingredient uniquely containing in 2, artemia extracts Thing has certain effect to promotion natural on-off cycles of hair growth tool.

Claims (3)

1. a kind of scalp tonic liquid processing alopecia and promoting natural on-off cycles of hair growth, includes:
A () accounts for the Flos lupuli (Flos Humuli Lupuli) extract of nourishing liquid weight 1-5%;
B () accounts for the Herba Rosmarini Officinalis extract of nourishing liquid weight 0.1-2%;
C () accounts for the Herba Swertiae bimaculatae extract of nourishing liquid weight 0.05-2%;
D () accounts for the artemia extract auxiliary activity composition of nourishing liquid weight 0.0075-0.15%;
E () cosmetically acceptable carrier, this carrier component and content are:
Account for the ethanol of nourishing liquid weight 8-35%;
Account for the Polyoxyl 40 Hydrogenated Castor Oil of nourishing liquid weight 0.05-3%;
Account for the d- pantothenylol of nourishing liquid weight 0.05-2%;
Appropriate preservative, essence, the deionized water of pigment, ph regulator and surplus.
2. scalp tonic liquid according to claim 1, wherein Flos lupuli (Flos Humuli Lupuli) extract account for nourishing liquid percentage by weight 1.5- 3%;Herba Rosmarini Officinalis extract accounts for nourishing liquid percentage by weight 0.5-1%;Herba Swertiae bimaculatae extract accounts for nourishing liquid percentage by weight 0.1- 0.8%;Artemia extract accounts for nourishing liquid percentage by weight 0.03-0.075%.
3. scalp tonic liquid according to claim 1, wherein in cosmetically acceptable carrier, ethanol accounts for nourishing liquid weight Percentage ratio 23-29%, Polyoxyl 40 Hydrogenated Castor Oil accounts for nourishing liquid percentage by weight 0.1-1.5%, and d- pantothenylol accounts for the present invention Nourishing liquid percentage by weight is 0.1-1%.
CN201610814302.1A 2016-09-09 2016-09-09 Scalp nourishing liquid for treating alopecia and promoting hair growth Active CN106333916B (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108992385A (en) * 2018-08-27 2018-12-14 天津市康婷生物工程有限公司 Hair essence is educated in a kind of hair follicle reparation
CN112137951A (en) * 2020-10-23 2020-12-29 天津强微特生物科技有限公司 Silicone-oil-free transparent amino acid shampoo capable of strengthening hair and repairing scalp barrier and preparation method thereof

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US6447762B1 (en) * 1999-01-29 2002-09-10 Colomer Group Spain, S.L. Hair lotion useful for treatment of hair loss and stimulating hair growth
CN103494754A (en) * 2013-08-27 2014-01-08 星彤(上海)化妆品科技有限公司 Anti-hair loss and hair-regeneration shampoo prepared from herbal essence and biochemical components and preparation method thereof
CN105919899A (en) * 2016-06-27 2016-09-07 北京普世安生物科技有限公司 Hair re-growing nourishing dew and preparation method thereof

Patent Citations (3)

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Publication number Priority date Publication date Assignee Title
US6447762B1 (en) * 1999-01-29 2002-09-10 Colomer Group Spain, S.L. Hair lotion useful for treatment of hair loss and stimulating hair growth
CN103494754A (en) * 2013-08-27 2014-01-08 星彤(上海)化妆品科技有限公司 Anti-hair loss and hair-regeneration shampoo prepared from herbal essence and biochemical components and preparation method thereof
CN105919899A (en) * 2016-06-27 2016-09-07 北京普世安生物科技有限公司 Hair re-growing nourishing dew and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108992385A (en) * 2018-08-27 2018-12-14 天津市康婷生物工程有限公司 Hair essence is educated in a kind of hair follicle reparation
CN112137951A (en) * 2020-10-23 2020-12-29 天津强微特生物科技有限公司 Silicone-oil-free transparent amino acid shampoo capable of strengthening hair and repairing scalp barrier and preparation method thereof

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