A kind of Betelnut buccal tablet and preparation method thereof
Technical field
Invention belongs to food processing technology field, is specifically related to a kind of Betelnut buccal tablet and preparation method thereof.
Background technology
Semen Arecae, has another name called that white side is bulky, Fructus Canarii albi is sub, Semen Arecae is beautiful, bulky jade etc., is the dry mature seed of babassu Semen Arecae,
Originate in states such as India, Sri Lanka, Thailand, Malaysia and Philippine.Semen Arecae has 1500 at China's introducing and planting
History, is all documented in Compendium of Material Medica and " flora ".China is one of main product ground of Semen Arecae, cultivated area and yield
The most on a large scale, account for about the 20% of Gross World Product at present, be mainly distributed on Hainan, Taiwan, Guangxi, Yunnan, Fujian etc. and save
(district).In Taiwan, the Semen Arecae output value is only second to rice and becomes the agricultural product of second largest ancestor, defines emerging Semen Arecae industry;?
Hainan, Semen Arecae is only second to rubber and occupies second, is one of main source of finance of east, middle part and Mountain Areas of Southern peasant.
Semen Arecae mainly has medicinal and edible two kinds of forms, and the seed of Semen Arecae, peel, flower etc. all can be used as medicine, be that China four is big
South one of medicine, has teeth consolidating sterilization, promoting digestion, disappear the effect such as tinea pedis and anthelmintic.It addition, Semen Arecae also can as food consumption,
Especially in Southeast Asia, the South Sea Islands and surrounding area, save including Hainan of China, Taiwan, Hunan etc., people generally like
Chewing food Semen Arecae, therefore the produced Semen Arecae in the various places overwhelming majority is consumed with the form of edible areca-nut.At present, the whole world there are about the people of 1,000,000,000
Edible Bin, Semen Arecae has become the fourth-largest hobby in the world article being only second to nicotine, ethanol and caffeine, it can be seen that Semen Arecae
Consumption market is huge.
Modern study shows, Semen Arecae has anthelmintic, stimulates sympathetic nerve, excited M cholinoceptor, refreshes oneself, removing food stagnancy, promoting the circulation of QI profit
Water, dampness removing is except the life activity such as subcutaneous ulcer or effect, and the active component that its that this mainly has benefited from contains: arecoline, arecaidine,
Guvacolining and the alkaloid such as demethyl arecaidine, therefore appropriateness is chewed food Semen Arecae and is had certain dietetic therapy and health care is made
With.But Semen Arecae is rich in crude fibre and alkaloid, excessive edible areca-nut can rub oral mucosa, easily causes mucosa and repeatedly creates
Wound, forms local chronic damage, adds the alkaloid acceleration to Epithelial Cell Apoptosis, the most easily causes oral cavity disease
Disease, even produces canceration.Therefore, in order to overcome the hobby of the excessive betel quid chewing of consumer, prior art discloses some to be had
Refresh oneself, be beneficial to the succedaneum of the edible betel quid chewing of oral health etc..
As Chinese patent (publication number 101416674) discloses a kind of areca-nut chewing gum and preparation method thereof, it is the most former
Expect to be consisted of by blue or green Semen Arecae, natural liquid mixing, its percentage by weight be blue or green Semen Arecae be 80%-90%, natural liquid is
10%-20%;Described natural liquid is, by weight percentage, by xylitol 1%-8%, Semen Arecae dinner party with singsong girls in attendance 1%-8%, treasure
Pearl powder 1%-8%, Mel 5%-15%, edible gum base 0.5%-2% composition.This areca-nut chewing gum is to be cut by high-quality green grass or young crops Semen Arecae
Open, be made with Semen Arecae dinner party with singsong girls in attendance and natural liquid.This invention areca-nut chewing gum maintains the original local flavor of Semen Arecae, makes again mouthfeel
Soft fine and smooth, overcome Semen Arecae mouthfeel thick and stiff, eat and chew laborious, coarse shortcoming, and mask the bitterness of Semen Arecae, and health is done
Only, instant edible, be suitable to produce in enormous quantities, can be widely used for producing various taste, there is functions of whitening teeth, pre-anti-caries, also have
Tooth protection effect and calcium supplementing effect.
Technique scheme uses Fructus Canarii Semen Arecae to cut into pieces, is fabricated to the shape of chewing gum with Semen Arecae dinner party with singsong girls in attendance and natural liquid
Formula, although the more soft exquisiteness of mouthfeel, but Fructus Canarii Semen Arecae fiber is still present in product, is eaten for a long time and still can destroy oral cavity
Health, the succedaneum chewing hobby crowd especially as Semen Arecae has bigger defect.
As Chinese patent (publication number 102228180A) discloses a kind of Betelnut buccal tablet and preparation method thereof, extract Semen Arecae
Thing, carambola powder, Hainan Green Orange powder, Hainan green tangerine powder, Fructus Citri Limoniae powder, sweeting agent and magnesium stearate composition, its preparation process is first
Semen Arecae dry product is pulverized and sieved, extracts by ethanol microwave-ULTRASONIC COMPLEX after High Temperature High Pressure softens, after gained filter vacuum concentrates
Carry out being spray-dried to obtain Semen Arecae extract;Fresh carambola, Hainan Green Orange, Hainan green tangerine and lemon juicing, filtration, through spray dried
Dry carambola powder, Hainan Green Orange powder, Hainan green tangerine powder and Fructus Citri Limoniae powder, by dried Semen Arecae extract and carambola powder, Hainan
After green orange powder, Hainan green tangerine powder and Fructus Citri Limoniae powder carry out pelletize and sieve, add appropriate sweeting agent, magnesium stearate etc. and be sufficiently mixed
Rear tabletting i.e. obtains Betelnut buccal tablet.This invention has refreshes oneself, improves the health-care effecies such as the intestines and stomach, uses mainly as edible, health product,
It is widely used in various people, is especially suitable for the fatiguability crowds such as driver, use easy to carry, taste sweet and sour taste.
The Semen Arecae buccal tablet of technique scheme is prepared from Semen Arecae extract and other flavoring agents, has certain guarantor
Strong value, but it loses the taste of edible areca-nut substantially, especially with Hainan Green Orange powder, Hainan green tangerine powder and Fructus Citri Limoniae powder
After allotment, local flavor changes completely, is therefore difficult to become the succedaneum of edible betel quid chewing;It addition, its only carrying with Semen Arecae
Taking thing is raw material, can produce substantial amounts of Semen Arecae waste residue, and the utilization rate of Semen Arecae is the highest.
Summary of the invention
Chew food Semen Arecae and be always the living habit of the ground such as Hunan, Hainan people, chew food Semen Arecae descendant and often feel spirit
Excitement, stays in the common people of alpine belt in the past and often keeps out the cold and eliminate the fatigue after nervous work eating Semen Arecae, but excessively chew food
It is unfavorable for oral health.For the problems referred to above, the invention provides the manufacture method of a kind of Betelnut buccal tablet, it extracts with Semen Arecae
Thing, areca dregs micropowders are raw material, including extracting, prepare Semen Arecae extract powder, preparing areca dregs micropowders, pelletize, pressure
The steps such as sheet, the Betelnut buccal tablet taste prepared by the method is similar to chewing Semen Arecae, has the merit of facilitating digestion, refreshment
Effect, also reduces the risk in betel quid chewing injury oral cavity simultaneously, can become driver and like the good replacement of Semen Arecae crowd;
It addition, the utilization rate of the fruit whole to Semen Arecae of the method is high, the most do not produce Semen Arecae garbage.
The present invention is achieved through the following technical solutions.
A kind of manufacture method of Betelnut buccal tablet, the raw material including following percentage ratio is prepared from: Semen Arecae extract powder 20~
50%, areca dregs micropowders 10~40%, Sorbitol 20~40%, Mentholum 0.05~2%, magnesium stearate 1~3%;
Its preparation method comprises the following steps:
(1) extract: will dry betel nut fruit pulverize after cross 20 mesh sieves, the Semen Arecae fruit powder after sieving and water according to solid-liquid ratio 1:8~
1:10kg/L extracts, and collects lixiviating solution and areca dregs respectively, standby;
(2) Semen Arecae extract powder is prepared
A, concentration: the extracting solution that step (1) obtains is pumped in vacuum concentration pot and concentrate, obtain concentrated solution;
B, dust: concentrated solution is spray-dried, obtains Semen Arecae extract powder;
(3) areca dregs micropowders is prepared
A, it is dried: areca dregs is dried to moisture less than 10%;
B, pulverizing: pulverized by dried areca dregs, the granularity being crushed to areca dregs is less than 5 microns, obtains areca dregs
Just powder, standby;After areca dregs is pulverized, specific surface area sharply increases, the raising of follow-up enzymolysis efficiency;
C, enzymolysis: in areca dregs just powder, add the water of its weight 3-5 times quality, stir, add half fiber afterwards
Element enzyme, cellulase, carry out enzymolysis, and enzymolysis is centrifugal after terminating, and collects supernatant and precipitate;Spray after supernatant concentration
Mist is dried, and obtains enzymatic hydrolysate 1;By drying precipitate, obtain enzymatic hydrolysate 2;Merge enzymatic hydrolysate 1, enzymatic hydrolysate 2, obtain Semen Arecae
Slag zymolyte;Areca dregs just powder can produce a certain amount of dextrin by hemicellulase enzymolysis, and the cellulose meeting in areca dregs
Being become glucose by cellulase hydrolysis, therefore areca dregs zymolyte is enriched in the product of glucose and dextrin, can be as follow-up
Pelletize, the adjuvant of tabletting, this not only solves the Utilizing question of areca dregs, and can reduce the consumption of follow-up adjuvant;
D, again pulverizing: pulverized by areca dregs zymolyte, the granularity being crushed to areca dregs is less than 1 micron, obtains Semen Arecae
Slag micropowders, standby;
(4) pelletize: Semen Arecae extract powder, areca dregs micropowders, Sorbitol, Mentholum, magnesium stearate are pressed formula
Weigh and mix homogeneously, break into powder with pulverizer, cross 100 mesh sieves, by siftage atomizers spray 50%~100% ethanol
Solution pelletize, crosses 20~60 mesh sieves after granulating and drying, collect siftage, standby;
(5) tabletting: the material after pelletize stand a period of time after tabletting.
As concrete scheme, described Betelnut buccal tablet includes that the raw material of following percentage ratio is prepared from: Semen Arecae extract powder 30
~40%, areca dregs micropowders 15~20%, Sorbitol 20~35%, maltodextrin 12~20%, malic acid 3%, osmanthus
Oil essence 5%, sucralose 1%, Mentholum 1%, magnesium stearate 2%;Its preparation method comprises the following steps:
(1) extract: will dry betel nut fruit pulverize after cross 20 mesh sieves, the Semen Arecae fruit powder after sieving and water according to solid-liquid ratio 1:8~
1:10kg/L extracts, and collects lixiviating solution and areca dregs respectively, standby;
(2) Semen Arecae extract powder is prepared
A, concentration: the extracting solution that step (1) obtains is pumped in vacuum concentration pot and concentrate, obtain concentrated solution;
B, dust: concentrated solution is spray-dried, obtains Semen Arecae extract powder;
(3) areca dregs micropowders is prepared
A, it is dried: areca dregs is dried to moisture less than 10%;
B, pulverizing: pulverized by dried areca dregs, the granularity being crushed to areca dregs is less than 5 microns, obtains areca dregs
Just powder, standby;
C, enzymolysis: in areca dregs just powder, add the water of its weight 3-5 times quality, stir, add half fiber afterwards
Element enzyme, cellulase, carry out enzymolysis, and enzymolysis is centrifugal after terminating, and collects supernatant and precipitate;Spray after supernatant concentration
Mist is dried, and obtains enzymatic hydrolysate 1;By drying precipitate, obtain enzymatic hydrolysate 2;Merge enzymatic hydrolysate 1, enzymatic hydrolysate 2, obtain Semen Arecae
Slag zymolyte;
D, again pulverizing: pulverized by areca dregs zymolyte, the granularity being crushed to areca dregs is less than 1 micron, obtains Semen Arecae
Slag micropowders, standby;
(4) pelletize: by Semen Arecae extract powder, areca dregs micropowders, Sorbitol, maltodextrin, malic acid, cassia oil is fragrant
Essence, sucralose, Mentholum, magnesium stearate is weighed and mix homogeneously by formula, breaks into powder with pulverizer, crosses 100 mesh sieves, will
Siftage atomizers spray 50%~100% ethanol solution pelletize, crosses 20~60 mesh sieves, collects siftage after granulating and drying,
Standby;
(5) tabletting: the material after pelletize stand a period of time after tabletting.
As concrete scheme, the extraction of described step (1) uses in ultrasound wave countercurrent extraction tank and extracts, and extraction conditions is:
Extracting temperature 70~80 DEG C, extraction time 1~2h.
As concrete scheme, the extraction of described step (1) uses warm water stirring to extract, and extraction conditions is: control extraction temperature
Degree is 36~38 DEG C, lixiviating solution pH is 6.6~7.1, extracting at constant temperature 10~30min under the mixing speed of 40~80r/min;Temperature
The parameter that water stirring is extracted close to the condition of human oral cavity betel quid chewing, as oral temperature be about 37 DEG C, pH be 6.6~7.1,
Therefore this condition extracts the nutritional labeling that obtains and to chew the nutrition of absorption, flavor substance even more like in oral cavity.
As concrete scheme, the stirring of described warm water adds amylase during extracting;
As the condition concentrated in concrete scheme, described step (2) it is: concentration time 1~2h, thickening temperature is 50~60
℃。
As concrete scheme, the condition dusted in described step (2) is: inlet temperature 180~200 DEG C, leaving air temp 80
~100 DEG C.
A kind of Betelnut buccal tablet, the raw material including following percentage ratio is prepared from: Semen Arecae extract powder 20~50%, areca dregs
Micropowders 10~40%, Sorbitol 20~40%, Mentholum 0.05~2%, magnesium stearate 1~3%;Its preparation method bag
Include following steps:
(1) extract: will dry betel nut fruit pulverize after cross 20 mesh sieves, the Semen Arecae fruit powder after sieving and water according to solid-liquid ratio 1:8~
1:10kg/L extracts, and collects lixiviating solution and areca dregs respectively, standby;
(2) Semen Arecae extract powder is prepared
A, concentration: the extracting solution that step (1) obtains is pumped in vacuum concentration pot and concentrate, obtain concentrated solution;
B, dust: concentrated solution is spray-dried, obtains Semen Arecae extract powder;
(3) areca dregs micropowders is prepared
A, it is dried: areca dregs is dried to moisture less than 10%;
B, pulverizing: pulverized by dried areca dregs, the granularity being crushed to areca dregs is less than 5 microns, obtains areca dregs
Just powder, standby;After areca dregs is pulverized, specific surface area sharply increases, the raising of follow-up enzymolysis efficiency;
C, enzymolysis: in areca dregs just powder, add the water of its weight 3-5 times quality, stir, add half fiber afterwards
Element enzyme, cellulase, carry out enzymolysis, and enzymolysis is centrifugal after terminating, and collects supernatant and precipitate;Spray after supernatant concentration
Mist is dried, and obtains enzymatic hydrolysate 1;By drying precipitate, obtain enzymatic hydrolysate 2;Merge enzymatic hydrolysate 1, enzymatic hydrolysate 2, obtain Semen Arecae
Slag zymolyte;Areca dregs just powder can produce a certain amount of dextrin by hemicellulase enzymolysis, and the cellulose meeting in areca dregs
Being become glucose by cellulase hydrolysis, therefore areca dregs zymolyte is enriched in the product of glucose and dextrin, can be as follow-up
Pelletize, the adjuvant of tabletting, this not only solves the Utilizing question of areca dregs, and can reduce the consumption of follow-up adjuvant;
D, again pulverizing: pulverized by areca dregs zymolyte, the granularity being crushed to areca dregs is less than 1 micron, obtains Semen Arecae
Slag micropowders, standby;
(4) pelletize: Semen Arecae extract powder, areca dregs micropowders, Sorbitol, Mentholum, magnesium stearate are pressed formula
Weigh and mix homogeneously, break into powder with pulverizer, cross 100 mesh sieves, by siftage atomizers spray 50%~100% ethanol
Solution pelletize, crosses 20~60 mesh sieves after granulating and drying, collect siftage, standby;
(5) tabletting: the material after pelletize stand a period of time after tabletting.
The Betelnut buccal tablet using the present invention has intrinsic local flavor and the effective ingredient of Semen Arecae, especially this buccal tablet and oral cavity
Local flavor during betel quid chewing is very close to, and can reduce excessive betel quid chewing cause oral cavity as the succedaneum of chewing Semen Arecae
The risk of injury, and without scum, beneficially environmental protection, and there is the function of refreshment, facilitating digestion, it is adaptable to driver class people
Group, safe ready;It addition, the inventive method achieves the comprehensive utilization of the whole fruit of Semen Arecae, Semen Arecae garbage will not be produced.
Detailed description of the invention
Below in conjunction with detailed description of the invention, the present invention is described further, it is pointed out that implementation below is only
It is the form enumerated indicative explaination that the present invention is done, but protection scope of the present invention is not limited to that, all
The technical staff in field each falls within protection scope of the present invention with the replacement of the equivalence that the present invention is done by the spirit of the present invention.
Embodiment 1
A kind of manufacture method of Betelnut buccal tablet, the raw material including following percentage ratio is prepared from: Semen Arecae extract powder 20~
50%, areca dregs micropowders 10~40%, Sorbitol 20~40%, Mentholum 0.05~2%, magnesium stearate 1~3%;
Its preparation method comprises the following steps:
(1) extract: will dry betel nut fruit pulverize after cross 20 mesh sieves, the Semen Arecae fruit powder after sieving and water according to solid-liquid ratio 1:8~
1:10kg/L extracts, and collects lixiviating solution and areca dregs respectively, standby;
(2) Semen Arecae extract powder is prepared
A, concentration: the extracting solution that step (1) obtains is pumped in vacuum concentration pot and concentrate, obtain concentrated solution;
B, dust: concentrated solution is spray-dried, obtains Semen Arecae extract powder;
(3) areca dregs micropowders is prepared
A, it is dried: areca dregs is dried to moisture less than 10%;
B, pulverizing: pulverized by dried areca dregs, the granularity being crushed to areca dregs is less than 5 microns, obtains areca dregs
Just powder, standby;
C, enzymolysis: in areca dregs just powder, add the water of its weight 3-5 times quality, stir, add half fiber afterwards
Element enzyme, cellulase, carry out enzymolysis, and enzymolysis is centrifugal after terminating, and collects supernatant and precipitate;Spray after supernatant concentration
Mist is dried, and obtains enzymatic hydrolysate 1;By drying precipitate, obtain enzymatic hydrolysate 2;Merge enzymatic hydrolysate 1, enzymatic hydrolysate 2, obtain Semen Arecae
Slag zymolyte;
D, again pulverizing: pulverized by areca dregs zymolyte, the granularity being crushed to areca dregs is less than 1 micron, obtains Semen Arecae
Slag micropowders, standby;
(4) pelletize: Semen Arecae extract powder, areca dregs micropowders, Sorbitol, Mentholum, magnesium stearate are pressed formula
Weigh and mix homogeneously, break into powder with pulverizer, cross 100 mesh sieves, by siftage atomizers spray 50%~100% ethanol
Solution pelletize, crosses 20~60 mesh sieves after granulating and drying, collect siftage, standby;
(5) tabletting: the material after pelletize stand a period of time after tabletting.
Embodiment 2
A kind of manufacture method of Betelnut buccal tablet, the raw material including following percentage ratio is prepared from: Semen Arecae extract powder 20%,
Areca dregs micropowders 40%, Sorbitol 30%, Mentholum 2%, magnesium stearate 3%;Its preparation method comprises the following steps:
(1) extract: will dry betel nut fruit pulverize after cross 20 mesh sieves, the Semen Arecae fruit powder after sieving and water according to solid-liquid ratio 1:8~
1:10kg/L extracts, and collects lixiviating solution and areca dregs respectively, standby;
(2) Semen Arecae extract powder is prepared
A, concentration: the extracting solution that step (1) obtains is pumped in vacuum concentration pot and concentrate, obtain concentrated solution;
B, dust: concentrated solution is spray-dried, obtains Semen Arecae extract powder;
(3) areca dregs micropowders is prepared
A, it is dried: areca dregs is dried to moisture less than 10%;
B, pulverizing: pulverized by dried areca dregs, the granularity being crushed to areca dregs is less than 5 microns, obtains areca dregs
Just powder, standby;
C, enzymolysis: in areca dregs just powder, add the water of its weight 3-5 times quality, stir, add half fiber afterwards
Element enzyme, cellulase, carry out enzymolysis, and enzymolysis is centrifugal after terminating, and collects supernatant and precipitate;Spray after supernatant concentration
Mist is dried, and obtains enzymatic hydrolysate 1;By drying precipitate, obtain enzymatic hydrolysate 2;Merge enzymatic hydrolysate 1, enzymatic hydrolysate 2, obtain Semen Arecae
Slag zymolyte;
D, again pulverizing: pulverized by areca dregs zymolyte, the granularity being crushed to areca dregs is less than 1 micron, obtains Semen Arecae
Slag micropowders, standby;
(4) pelletize: Semen Arecae extract powder, areca dregs micropowders, Sorbitol, Mentholum, magnesium stearate are pressed formula
Weigh and mix homogeneously, break into powder with pulverizer, cross 100 mesh sieves, by siftage atomizers spray 50%~100% ethanol
Solution pelletize, crosses 20~60 mesh sieves after granulating and drying, collect siftage, standby;
(5) tabletting: the material after pelletize stand a period of time after tabletting.
Embodiment 3
A kind of manufacture method of Betelnut buccal tablet, the raw material including following percentage ratio is prepared from: Semen Arecae extract powder 50%,
Areca dregs micropowders 10%, Sorbitol 20%, Mentholum 0.05%, magnesium stearate 1%;Its preparation method includes following step
Rapid:
(1) extract: will dry betel nut fruit pulverize after cross 20 mesh sieves, the Semen Arecae fruit powder after sieving and water according to solid-liquid ratio 1:8~
1:10kg/L extracts, and collects lixiviating solution and areca dregs respectively, standby;
(2) Semen Arecae extract powder is prepared
A, concentration: the extracting solution that step (1) obtains is pumped in vacuum concentration pot and concentrate, obtain concentrated solution;
B, dust: concentrated solution is spray-dried, obtains Semen Arecae extract powder;
(3) areca dregs micropowders is prepared
A, it is dried: areca dregs is dried to moisture less than 10%;
B, pulverizing: pulverized by dried areca dregs, the granularity being crushed to areca dregs is less than 5 microns, obtains areca dregs
Just powder, standby;
C, enzymolysis: in areca dregs just powder, add the water of its weight 3-5 times quality, stir, add half fiber afterwards
Element enzyme, cellulase, carry out enzymolysis, and enzymolysis is centrifugal after terminating, and collects supernatant and precipitate;Spray after supernatant concentration
Mist is dried, and obtains enzymatic hydrolysate 1;By drying precipitate, obtain enzymatic hydrolysate 2;Merge enzymatic hydrolysate 1, enzymatic hydrolysate 2, obtain Semen Arecae
Slag zymolyte;
D, again pulverizing: pulverized by areca dregs zymolyte, the granularity being crushed to areca dregs is less than 1 micron, obtains Semen Arecae
Slag micropowders, standby;
(4) pelletize: Semen Arecae extract powder, areca dregs micropowders, Sorbitol, Mentholum, magnesium stearate are pressed formula
Weigh and mix homogeneously, break into powder with pulverizer, cross 100 mesh sieves, by siftage atomizers spray 50%~100% ethanol
Solution pelletize, crosses 20~60 mesh sieves after granulating and drying, collect siftage, standby;
(5) tabletting: the material after pelletize stand a period of time after tabletting.
Embodiment 4
A kind of manufacture method of Betelnut buccal tablet, the raw material including following percentage ratio is prepared from: Semen Arecae extract powder 30%,
Areca dregs micropowders 30%, Sorbitol 30%, Mentholum 1%, magnesium stearate 2%;Its preparation method comprises the following steps:
(1) extract: will dry betel nut fruit pulverize after cross 20 mesh sieves, the Semen Arecae fruit powder after sieving and water according to solid-liquid ratio 1:8~
1:10kg/L extracts, and collects lixiviating solution and areca dregs respectively, standby;
(2) Semen Arecae extract powder is prepared
A, concentration: the extracting solution that step (1) obtains is pumped in vacuum concentration pot and concentrate, obtain concentrated solution;
B, dust: concentrated solution is spray-dried, obtains Semen Arecae extract powder;
(3) areca dregs micropowders is prepared
A, it is dried: areca dregs is dried to moisture less than 10%;
B, pulverizing: pulverized by dried areca dregs, the granularity being crushed to areca dregs is less than 5 microns, obtains areca dregs
Just powder, standby;
C, enzymolysis: in areca dregs just powder, add the water of its weight 3-5 times quality, stir, add half fiber afterwards
Element enzyme, cellulase, carry out enzymolysis, and enzymolysis is centrifugal after terminating, and collects supernatant and precipitate;Spray after supernatant concentration
Mist is dried, and obtains enzymatic hydrolysate 1;By drying precipitate, obtain enzymatic hydrolysate 2;Merge enzymatic hydrolysate 1, enzymatic hydrolysate 2, obtain Semen Arecae
Slag zymolyte;
D, again pulverizing: pulverized by areca dregs zymolyte, the granularity being crushed to areca dregs is less than 1 micron, obtains Semen Arecae
Slag micropowders, standby;
(4) pelletize: Semen Arecae extract powder, areca dregs micropowders, Sorbitol, Mentholum, magnesium stearate are pressed formula
Weigh and mix homogeneously, break into powder with pulverizer, cross 100 mesh sieves, by siftage atomizers spray 50%~100% ethanol
Solution pelletize, crosses 20~60 mesh sieves after granulating and drying, collect siftage, standby;
(5) tabletting: the material after pelletize stand a period of time after tabletting.
Embodiment 5
A kind of manufacture method of Betelnut buccal tablet, the raw material including following percentage ratio is prepared from: Semen Arecae extract powder 30~
40%, areca dregs micropowders 15~20%, Sorbitol 20~35%, maltodextrin 12~20%, malic acid 3%, cassia oil
Essence 5%, sucralose 1%, Mentholum 1%, magnesium stearate 2%;Its preparation method comprises the following steps:
(1) extract: will dry betel nut fruit pulverize after cross 20 mesh sieves, the Semen Arecae fruit powder after sieving and water according to solid-liquid ratio 1:8~
1:10kg/L extracts, and collects lixiviating solution and areca dregs respectively, standby;
(2) Semen Arecae extract powder is prepared
A, concentration: the extracting solution that step (1) obtains is pumped in vacuum concentration pot and concentrate, obtain concentrated solution;
B, dust: concentrated solution is spray-dried, obtains Semen Arecae extract powder;
(3) areca dregs micropowders is prepared
A, it is dried: areca dregs is dried to moisture less than 10%;
B, pulverizing: pulverized by dried areca dregs, the granularity being crushed to areca dregs is less than 5 microns, obtains areca dregs
Just powder, standby;
C, enzymolysis: in areca dregs just powder, add the water of its weight 3-5 times quality, stir, add half fiber afterwards
Element enzyme, cellulase, carry out enzymolysis, and enzymolysis is centrifugal after terminating, and collects supernatant and precipitate;Spray after supernatant concentration
Mist is dried, and obtains enzymatic hydrolysate 1;By drying precipitate, obtain enzymatic hydrolysate 2;Merge enzymatic hydrolysate 1, enzymatic hydrolysate 2, obtain areca dregs
Zymolyte;
D, again pulverizing: pulverized by areca dregs zymolyte, the granularity being crushed to areca dregs is less than 1 micron, obtains Semen Arecae
Slag micropowders, standby;
(4) pelletize: by Semen Arecae extract powder, areca dregs micropowders, Sorbitol, maltodextrin, malic acid, cassia oil is fragrant
Essence, sucralose, Mentholum, magnesium stearate is weighed and mix homogeneously by formula, breaks into powder with pulverizer, crosses 100 mesh sieves, will
Siftage atomizers spray 50%~100% ethanol solution pelletize, crosses 20~60 mesh sieves, collects siftage after granulating and drying,
Standby;
(5) tabletting: the material after pelletize stand a period of time after tabletting.
Embodiment 6
A kind of manufacture method of Betelnut buccal tablet, the raw material including following percentage ratio is prepared from: Semen Arecae extract powder 20~
50%, areca dregs micropowders 10~40%, Sorbitol 20~40%, Mentholum 0.05~2%, magnesium stearate 1~3%;
Its preparation method comprises the following steps:
(1) extract: will dry betel nut fruit pulverize after cross 20 mesh sieves, the Semen Arecae fruit powder after sieving and water according to solid-liquid ratio 1:8~
1:10kg/L extracts, and extraction uses in ultrasound wave countercurrent extraction tank and extracts, and extraction conditions is: Extracting temperature 70~80 DEG C,
Extraction time 1~2h, collect lixiviating solution and areca dregs respectively, standby;
(2) Semen Arecae extract powder is prepared
A, concentration: the extracting solution that step (1) obtains is pumped in vacuum concentration pot and concentrate, obtain concentrated solution;
B, dust: concentrated solution is spray-dried, obtains Semen Arecae extract powder;
(3) areca dregs micropowders is prepared
A, it is dried: areca dregs is dried to moisture less than 10%;
B, pulverizing: pulverized by dried areca dregs, the granularity being crushed to areca dregs is less than 5 microns, obtains areca dregs
Just powder, standby;
C, enzymolysis: in areca dregs just powder, add the water of its weight 3-5 times quality, stir, add half fiber afterwards
Element enzyme, cellulase, carry out enzymolysis, and enzymolysis is centrifugal after terminating, and collects supernatant and precipitate;Spray after supernatant concentration
Mist is dried, and obtains enzymatic hydrolysate 1;By drying precipitate, obtain enzymatic hydrolysate 2;Merge enzymatic hydrolysate 1, enzymatic hydrolysate 2, obtain Semen Arecae
Slag zymolyte;
D, again pulverizing: pulverized by areca dregs zymolyte, the granularity being crushed to areca dregs is less than 1 micron, obtains Semen Arecae
Slag micropowders, standby;
(4) pelletize: Semen Arecae extract powder, areca dregs micropowders, Sorbitol, Mentholum, magnesium stearate are pressed formula
Weigh and mix homogeneously, break into powder with pulverizer, cross 100 mesh sieves, by siftage atomizers spray 50%~100% ethanol
Solution pelletize, crosses 20~60 mesh sieves after granulating and drying, collect siftage, standby;
(5) tabletting: the material after pelletize stand a period of time after tabletting.
Embodiment 7
A kind of manufacture method of Betelnut buccal tablet, the raw material including following percentage ratio is prepared from: Semen Arecae extract powder 20~
50%, areca dregs micropowders 10~40%, Sorbitol 20~40%, Mentholum 0.05~2%, magnesium stearate 1~3%;
Its preparation method comprises the following steps:
(1) extract: will dry betel nut fruit pulverize after cross 20 mesh sieves, the Semen Arecae fruit powder after sieving and water according to solid-liquid ratio 1:8~
1:10kg/L extracts, and extraction uses warm water stirring to extract, and extraction conditions is: controlling extraction temperature is 36~38 DEG C, extraction
Liquid pH is 6.6~7.1, extracting at constant temperature 10~30min under the mixing speed of 40~80r/min, collects lixiviating solution and Bin respectively
Bulky slag, standby;
(2) Semen Arecae extract powder is prepared
A, concentration: the extracting solution that step (1) obtains is pumped in vacuum concentration pot and concentrate, obtain concentrated solution;
B, dust: concentrated solution is spray-dried, obtains Semen Arecae extract powder;
(3) areca dregs micropowders is prepared
A, it is dried: areca dregs is dried to moisture less than 10%;
B, pulverizing: pulverized by dried areca dregs, the granularity being crushed to areca dregs is less than 5 microns, obtains areca dregs
Just powder, standby;
C, enzymolysis: in areca dregs just powder, add the water of its weight 3-5 times quality, stir, add half fiber afterwards
Element enzyme, cellulase, carry out enzymolysis, and enzymolysis is centrifugal after terminating, and collects supernatant and precipitate;Spray after supernatant concentration
Mist is dried, and obtains enzymatic hydrolysate 1;By drying precipitate, obtain enzymatic hydrolysate 2;Merge enzymatic hydrolysate 1, enzymatic hydrolysate 2, obtain Semen Arecae
Slag zymolyte;
D, again pulverizing: pulverized by areca dregs zymolyte, the granularity being crushed to areca dregs is less than 1 micron, obtains Semen Arecae
Slag micropowders, standby;
(4) pelletize: Semen Arecae extract powder, areca dregs micropowders, Sorbitol, Mentholum, magnesium stearate are pressed formula
Weigh and mix homogeneously, break into powder with pulverizer, cross 100 mesh sieves, by siftage atomizers spray 50%~100% ethanol
Solution pelletize, crosses 20~60 mesh sieves after granulating and drying, collect siftage, standby;
(5) tabletting: the material after pelletize stand a period of time after tabletting.
Embodiment 8
A kind of manufacture method of Betelnut buccal tablet, the raw material including following percentage ratio is prepared from: Semen Arecae extract powder 20~
50%, areca dregs micropowders 10~40%, Sorbitol 20~40%, Mentholum 0.05~2%, magnesium stearate 1~3%;
Its preparation method comprises the following steps:
(1) extract: will dry betel nut fruit pulverize after cross 20 mesh sieves, the Semen Arecae fruit powder after sieving and water according to solid-liquid ratio 1:8~
1:10kg/L extracts, and extraction uses warm water stirring to extract, and extraction conditions is: controlling extraction temperature is 36~38 DEG C, extraction
Liquid pH is 6.6~7.1, extracting at constant temperature 10~30min under the mixing speed of 40~80r/min, collects lixiviating solution and Bin respectively
Bulky slag, standby;The stirring of described warm water adds amylase during extracting;
(2) Semen Arecae extract powder is prepared
A, concentration: the extracting solution that step (1) obtains is pumped in vacuum concentration pot and concentrate, obtain concentrated solution;
B, dust: concentrated solution is spray-dried, obtains Semen Arecae extract powder;
(3) areca dregs micropowders is prepared
A, it is dried: areca dregs is dried to moisture less than 10%;
B, pulverizing: pulverized by dried areca dregs, the granularity being crushed to areca dregs is less than 5 microns, obtains areca dregs
Just powder, standby;
C, enzymolysis: in areca dregs just powder, add the water of its weight 3-5 times quality, stir, add half fiber afterwards
Element enzyme, cellulase, carry out enzymolysis, and enzymolysis is centrifugal after terminating, and collects supernatant and precipitate;Spray after supernatant concentration
Mist is dried, and obtains enzymatic hydrolysate 1;By drying precipitate, obtain enzymatic hydrolysate 2;Merge enzymatic hydrolysate 1, enzymatic hydrolysate 2, obtain Semen Arecae
Slag zymolyte;
D, again pulverizing: pulverized by areca dregs zymolyte, the granularity being crushed to areca dregs is less than 1 micron, obtains Semen Arecae
Slag micropowders, standby;
(4) pelletize: Semen Arecae extract powder, areca dregs micropowders, Sorbitol, Mentholum, magnesium stearate are pressed formula
Weigh and mix homogeneously, break into powder with pulverizer, cross 100 mesh sieves, by siftage atomizers spray 50%~100% ethanol
Solution pelletize, crosses 20~60 mesh sieves after granulating and drying, collect siftage, standby;
(5) tabletting: the material after pelletize stand a period of time after tabletting.
Embodiment 9
A kind of manufacture method of Betelnut buccal tablet, the raw material including following percentage ratio is prepared from: Semen Arecae extract powder 20~
50%, areca dregs micropowders 10~40%, Sorbitol 20~40%, Mentholum 0.05~2%, magnesium stearate 1~3%;
Its preparation method comprises the following steps:
(1) extract: will dry betel nut fruit pulverize after cross 20 mesh sieves, the Semen Arecae fruit powder after sieving and water according to solid-liquid ratio 1:8~
1:10kg/L extracts, and collects lixiviating solution and areca dregs respectively, standby;
(2) Semen Arecae extract powder is prepared
A, concentration: the extracting solution that step (1) obtains is pumped in vacuum concentration pot and concentrate, concentration time 1~2h, concentrate temperature
Degree is 50~60 DEG C, obtains concentrated solution;
B, dust: concentrated solution is spray-dried, obtains Semen Arecae extract powder;
(3) areca dregs micropowders is prepared
A, it is dried: areca dregs is dried to moisture less than 10%;
B, pulverizing: pulverized by dried areca dregs, the granularity being crushed to areca dregs is less than 5 microns, obtains areca dregs
Just powder, standby;
C, enzymolysis: in areca dregs just powder, add the water of its weight 3-5 times quality, stir, add half fiber afterwards
Element enzyme, cellulase, carry out enzymolysis, and enzymolysis is centrifugal after terminating, and collects supernatant and precipitate;Spray after supernatant concentration
Mist is dried, and obtains enzymatic hydrolysate 1;By drying precipitate, obtain enzymatic hydrolysate 2;Merge enzymatic hydrolysate 1, enzymatic hydrolysate 2, obtain Semen Arecae
Slag zymolyte;
D, again pulverizing: pulverized by areca dregs zymolyte, the granularity being crushed to areca dregs is less than 1 micron, obtains Semen Arecae
Slag micropowders, standby;
(4) pelletize: Semen Arecae extract powder, areca dregs micropowders, Sorbitol, Mentholum, magnesium stearate are pressed formula
Weigh and mix homogeneously, break into powder with pulverizer, cross 100 mesh sieves, by siftage atomizers spray 50%~100% ethanol
Solution pelletize, crosses 20~60 mesh sieves after granulating and drying, collect siftage, standby;
(5) tabletting: the material after pelletize stand a period of time after tabletting.
Embodiment 10
A kind of manufacture method of Betelnut buccal tablet, the raw material including following percentage ratio is prepared from: Semen Arecae extract powder 20~
50%, areca dregs micropowders 10~40%, Sorbitol 20~40%, Mentholum 0.05~2%, magnesium stearate 1~3%;
Its preparation method comprises the following steps:
(1) extract: will dry betel nut fruit pulverize after cross 20 mesh sieves, the Semen Arecae fruit powder after sieving and water according to solid-liquid ratio 1:8~
1:10kg/L extracts, and collects lixiviating solution and areca dregs respectively, standby;
(2) Semen Arecae extract powder is prepared
A, concentration: the extracting solution that step (1) obtains is pumped in vacuum concentration pot and concentrate, obtain concentrated solution;
B, dust: concentrated solution is spray-dried, inlet temperature 180~200 DEG C are set, leaving air temp 80~100 DEG C,
Obtain Semen Arecae extract powder;
(3) areca dregs micropowders is prepared
A, it is dried: areca dregs is dried to moisture less than 10%;
B, pulverizing: pulverized by dried areca dregs, the granularity being crushed to areca dregs is less than 5 microns, obtains areca dregs
Just powder, standby;
C, enzymolysis: in areca dregs just powder, add the water of its weight 3-5 times quality, stir, add half fiber afterwards
Element enzyme, cellulase, carry out enzymolysis, and enzymolysis is centrifugal after terminating, and collects supernatant and precipitate;Spray after supernatant concentration
Mist is dried, and obtains enzymatic hydrolysate 1;By drying precipitate, obtain enzymatic hydrolysate 2;Merge enzymatic hydrolysate 1, enzymatic hydrolysate 2, obtain Semen Arecae
Slag zymolyte;
D, again pulverizing: pulverized by areca dregs zymolyte, the granularity being crushed to areca dregs is less than 1 micron, obtains Semen Arecae
Slag micropowders, standby;
(4) pelletize: Semen Arecae extract powder, areca dregs micropowders, Sorbitol, Mentholum, magnesium stearate are pressed formula
Weigh and mix homogeneously, break into powder with pulverizer, cross 100 mesh sieves, by siftage atomizers spray 50%~100% ethanol
Solution pelletize, crosses 20~60 mesh sieves after granulating and drying, collect siftage, standby;
(5) tabletting: the material after pelletize stand a period of time after tabletting.
Embodiment 11
Betelnut buccal tablet prepared by method as described in embodiment 1.