CN106265462A - A kind of component-type freckle-removing beauty cream and preparation method - Google Patents
A kind of component-type freckle-removing beauty cream and preparation method Download PDFInfo
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- CN106265462A CN106265462A CN201610914087.2A CN201610914087A CN106265462A CN 106265462 A CN106265462 A CN 106265462A CN 201610914087 A CN201610914087 A CN 201610914087A CN 106265462 A CN106265462 A CN 106265462A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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Abstract
The present invention relates to a kind of component-type freckle-removing beauty cream and preparation method, belong to anti-spot beautifying skin-care product technical field.It uses in component A and B component the raw materials such as the hirudin of certain part by weight, Periostracum Cicadae, Periostracum Serpentis, kojic acid, is prepared from by present invention process.Hirudin has skin expansion blood capillary, improves corium blood microcirculation, promotes melanocyte metabolism, effect that permeability is absorbed by Skin Cell by force and easily.Periostracum Serpentis and Periostracum Cicadae can accelerate skin surface cell metabolism and epidermis speckle falling speed and new skin generates, and have enhancing skin elasticity and eliminate mottle effect.Kojic acid plays water conservation and increases skin elasticity effect, good for mottle such as freckle, Pigmented therapeutic effect.Manufacture method is simple, and speckle dispelling instant effect, treatment cycle is short, does not damage skin of face, cheap, easy to use.Solve existing chemistry cosmetics infringement skin, and existing Chinese medicine is controlled mottle and be there is cycle length, curative effect slowly, complex manufacturing, the problem that manufacturing cost is high.
Description
Technical field
The present invention relates to a kind of component-type freckle-removing beauty cream and preparation method, belong to anti-spot beautifying skin-care product technical field.
Background technology
Mottle is a kind of dermatopathy formed owing to dermal melanin increases, and is mainly in women buccal and frons
Position, freckle, cyasma, black speck, chloasma are referred to as mottle.Mottle occurs, not only affects external beauty, and can be to patient's heart
Intense stimulus, time one length is caused to may result in patient's internal organs organ lesion and cause severe disease.Therefore, speckle dispelling is without minor matter.At present
Cosmetics kind on market is more, but the general infringement hydrargyrum of skin, lead and the hormone of all containing, and use covering, " mill more
Thin " skin mode carries out speckle dispelling and whitening, and toxic and side effects is big, easily causes dependency and the anaphylaxis of skin, once disables, skin
Skin can obscure, cicatrix occurs, even face is red and swollen for some people, fester.By Chinese herbal treatment mottle, chemistry speckle dispelling can be avoided
The injury that skin is caused by the toxic and side effects of cosmetic, safe and reliable, but there is also treatment mottle cycle length, take effect slowly,
Complex manufacturing, the problem that manufacturing cost is high.
Summary of the invention
It is an object of the invention to, for above-mentioned the deficiencies in the prior art, it is provided that a kind of manufacture method is simple, and speckle dispelling takes effect
Hurry up, treatment cycle is short, has no side effect, and does not damage skin of face, cheap, component-type freckle-removing beauty cream easy to use and
Preparation method.
The present invention is to realize above-mentioned purpose by the following technical solutions:
A kind of component-type freckle-removing beauty cream, it is characterised in that: it is made up of component A and B component, wherein:
Component A is made up of the raw material of following weight parts: Hirudo live body or Hirudo live body freeze product 1～10 parts；
B component is made up of the raw material of following weight parts: Periostracum Cicadae 1～10 parts, Periostracum Serpentis 1～10 parts, kojic acid 0.01～0.04 part, cosmetic
Product simple emulsifying agent 0.1～0.5 part, Fragrance qs.
Described component-type freckle-removing beauty cream is prepared from by following processing step:
1), hirudin is extracted:
Weigh Hirudo live body by component A weight portion or Hirudo live body freezes product, pulverize, add 5 times of normal saline, stirring
Extract 30 minutes, centrifugal, filter to obtain hirudin extracting solution；Membrane filtration hirudin extracting solution, removes the pigments such as residual hemoglobin,
Less than 4 DEG C cryoconcentration, are distributed in 30 cillin bottles, lyophilizing, obtain hirudin；
2) Periostracum Cicadae and Periostracum Serpentis concentrated solution are extracted:
Slightly carry: weigh Periostracum Cicadae and Periostracum Serpentis respectively by B component weight portion, Periostracum Cicadae and Periostracum Serpentis are cleaned, dry, pulverize, mix, add
Periostracum Cicadae and the pure water of Periostracum Serpentis gross weight ten times, be warming up to 100 DEG C, after keeping 2 minutes, cools to 80 DEG C, keeps 80 DEG C of temperature to stir
Mix extraction 2 hours, filter, waste；
Concentrate: the extracting solution concentrating under reduced pressure below 50 DEG C that will slightly raise, be concentrated into 1/the 20 of original volume；Continue cooling
To room temperature, add kojic acid, simple emulsifying agent used for cosmetic and spice, stir and i.e. prepare concentrated solution, bottle stand-by.
The using method of described component-type freckle-removing beauty cream is as follows:
The first step: first use warm water cleaning skin, and apply face 3～5 minutes with hot towel, thoroughly to open pore；
Second step: take component A hirudin lyophilized powder, opens cillin bottle sealing, adds 3ml normal saline, rock dissolving；
3rd step: be applied to rapidly on the face by sufficient for dissolving hirudin solution, pats skin gently and fills by hirudin after smearing
Divide and absorb；
4th step: after face is the most dry, takes B component appropriate, and uniform application on the face, washes away after half an hour.
In this component-type freckle-removing beauty cream and preparation method, effect of various raw materials is as follows:
Hirudin: be that in the various active composition extracted in Hirudo and salivary gland thereof, activity is the most notable and studies
Most a kind of compositions.The small protein (polypeptide) that hirudin is made up of 65 66 aminoacid.Hirudin is to blood coagulation
Enzyme has extremely strong inhibitory action, is the strongest natural specific inhibitor of thrombin found up to now.Animal experiment is with clinical
Research shows, hirudin energy Effective Anti blood coagulation, antithrombus formation, and stops the thrombin activation of catalyzed by thrombin and blood little
The blood stasis phenomenon further such as plate reaction.Additionally, hirudin can also fibroblastic propagation of enzyme induction anticoagulant and blood coagulation
The stimulation of enzyme Human Umbilical Vein Endothelial Cells.Compared with heparin, it not only consumption few, will not cause bleeding, also not dependent on endogenous assist
The factor.
Due to hirudin molecular weight minimum (molecular weight is 4,000 7000 dalton), there is outstanding permeability and extremely strong
The effect improving microcirculation, enhancing metabolism, therefore, natural hirudin lyophilized powder can dredge and expand skin of face capillary
Blood vessel, improves corium blood microcirculation, promotes melanocyte metabolism, and penetrate to the skin rapidly deep layer, is easily inhaled by Skin Cell
Receive.On the other hand, hirudin dredging blood capillary, improves face microcirculation, promotes skin metabolism, can fundamentally solve
All kinds of skin problems such as mottle, comedo, scar print, red blood streak, pigmentation.Hirudin for oral administration, it is also possible to play general and adjust
Joint effect, these effects almost relate to all physiological activities of human body, such as: endocrine, digest, absorb, metabolism, grow, give birth to
Grow and nerve etc..In 21st Guangzhou International Cosmetic cosmetics fair of in JIUYUE, 2004, hirudin is considered as this review
The new product that science and technology gold content is the highest can be gone up.The appearance of hirudin cosmetics, indicates that the hirudin beauty treatment epoch have arrived.
Periostracum Cicadae: Chinese medicine name, its holotype is hollow like Cicadae, slightly bent.Periostracum Cicadae medicinal part: after sprouting wings for cicada Cryptotympana atrata Fabr.
Shell.Periostracum Cicadae sweet in the mouth, salty, cool in nature.Periostracum Cicadae returns lung, Liver Channel.Periostracum Cicadae has dispelling wind and heat pathogens, relieving sore throat to recover voice, rash, and improving eyesight is moved back
Nebula, effect of endogenous wind stopping relieving convulsion.Periostracum Cicadae can accelerate the accretion rate of skin surface cell, accelerates coming off and new rawhide of epidermis speckle
The generation of skin, thus reach to strengthen skin elasticity, the purpose of elimination mottle；Meanwhile, Periostracum Cicadae also has alleviation skin pruritus, antipyretic
And anti-allergic effects.
Periostracum Serpentis: Chinese medicine name.Dry epidermis film under sloughing off for Colubridae animal Elaphe taeniurus Cope, rat snake or Zaocys etc..Spring Mo
Early summer or collection at the beginning of the winter, remove silt, be dried.Periostracum Serpentis salty in the mouth, sweet, property is put down.Periostracum Serpentis returns Liver Channel.Periostracum Serpentis has and dispels the wind, arresting convulsion, moves back
Nebula, the effect of removing toxic substances.Periostracum Serpentis cures mainly: infantile convulsion, tic spasm, cataracta, sore throat, treats swollen, skin pruritus." Bencao Jingshu ":
Periostracum Serpentis, enters liver and wards off evil, pediatric epilepsy scared, ruined disease cold and heat, Serpentis epilepsy frequent protrusion of the tongue shakes the head, adult's five pathogenic factors, and speech is out-of-the-way more, all Liver Channel
For disease, Periostracum Serpentis can draw all medicines and enter the scattered heresy of liver, therefore main such as first-class card.Kind energy parasite killing, therefore main perianal abscess insect poison malignant boil.Heresy goes wood flat, therefore
Preventing or arresting vomiting coughs improving eyesight.Periostracum Serpentis as Periostracum Cicadae, have accelerate skin surface cell accretion rate, accelerate epidermis speckle come off and
The generation of neoplastic skin, reaches to strengthen skin elasticity, eliminates effect of mottle；The most also have alleviation skin pruritus, antipyretic and
Anti-allergic effects.
Kojic acid: chemical name is 5-hydroxy-2-hydroxamethy-1,4-pyrone.It is present in the wine of soy sauce, broad bean paste and drinks
In making.The existence of kojic acid is may detect that with aspergillosis in the fermented product that many is fermented.More kojic acid is applied and is led at cosmetics
Territory and food processing field.Kojic acid has another name called kojic acid, Qu acid, is a kind of melanin specificity inhibitor, and it enters Skin Cell
After the stereochemical structure of tryrosinase with the copper ion complexation in cell, can be changed, stop the activation of tryrosinase, thus suppress
Melanic formation.Kojic acid class whitening active agent has more preferable tryrosinase inhibition compared with other whitening active agent.It is not
Acting on other enzyme in cell, cell is not had toxic action, it can also enter in intercellular substance simultaneously, forms intercellular
Colloid, plays water conservation and increases the effect of skin elasticity.Allocated in various cosmetics at present, made for freckle, old man
The skin-lightening cosmetic of speckle, pigmentation and acne.
Simple emulsifying agent used for cosmetic: be the material promoting two kinds of immiscible liquid to form stabilized emulsion.Emulsifying
Agent has certain bacteriostasis, is usually used in fruit and plays anti-rotten preservation.Emulsifying agent is used for cosmetics, in addition to emulsification,
Also have concurrently solubilising, be impregnated with, the effect such as moistening.Simple emulsifying agent used for cosmetic stays any chemistry to repair at horny layer hardly
Decorations, this kind of New-type emulsifier simply contacts with water and works, lipid material is transported skin, reaches cleaning and the effect washed out
Really.
Emulsifying agent for food industry be mostly sucrose fatty acid ester, lecithin, glycerol list citrate, granulesten,
Sorbitan fatty acid ester and dextrin etc..Mostly emulsifying agent for cosmetics is poly(ethylene oxide) fatty acid glyceride, dehydration
Sorbitol poly(ethylene oxide) four oleate, alkylphenol polyethylene oxide ether and sorbitol poly(ethylene oxide) ether etc..
Spice: be a kind of to be smelt fragrance or the material of fragrance tasted by the sense of taste by olfactory sensation, be the raw material of preparation essence.
Spice is the important component part of fine chemicals, and it is by natural perfume material, synthetic perfume and mono-isolate 3 part composition
's.Spice possesses spectacular aromatic odor, releive body and mind and effect for the treatment of more soul, is widely used in food, day
The industries such as change, Nicotiana tabacum L., medicine, closely bound up with daily life.Vegetal natural perfume is the flower using fragrant plant,
Branch, leaf, grass, root, skin, stem, seed or fruit etc. are raw material, by methods such as steam distillation, extraction, milling process, absorption processes, raw
The quintessence oil that output is come, extractum, tincture, face cream, balsam and absolute oil etc., such as Oleum Rosae Rugosae, concrete of jasmine, vanilla tincture, white orchid
Face cream, tells LUXIANG resin, narcissus absolute oil etc..Animality natural perfume material is secretions or the Excreta of animal.The natural perfume (or spice) of animality
Material has ten several, it is possible to form commodity and only Moschus, Ambra Grisea, Zibethum and the castoreum 4 kinds of often application, conventional ethanol
Use after being made into tincture.Spices and essence is widely used in fancy soap, detergent, various cosmetics such as cold cream, vanishing cream, sends out
The environmental healths such as breast, pomade, shampoo, floral water and perfume etc., skin cosmetic, toothpaste, air freshener and antibacterial are used
Product, confection, cookies, beverage, cigarette, wine, soyabean milk, milk product, vegetable protein food, and medicine, paper, plastics, leather, fabric
Deng perfuming.
The present invention having the beneficial effects that compared with prior art:
This component-type freckle-removing beauty cream and preparation method use the raw material hirudin of component A certain part by weight and B component necessarily to weigh
Amount the raw material Periostracum Cicadae of part, Periostracum Serpentis, kojic acid, spice, simple emulsifying agent used for cosmetic, be prepared from by present invention process.Hirudo
Element has dredging and expansion skin of face blood capillary, improves corium blood microcirculation, promotes melanocyte metabolism, and rapidly
Effect that the deep layer that penetrates to the skin is absorbed by Skin Cell.Periostracum Serpentis, as Periostracum Cicadae, has the metabolism accelerating skin surface cell
Speed, accelerates coming off and the generation of neoplastic skin of epidermis speckle, reaches to strengthen skin elasticity, eliminates effect of mottle；Simultaneously
Also there is alleviation skin pruritus, antipyretic and anti-allergic effects.Kojic acid class whitening active agent relatively other whitening active agent has more preferably
Tryrosinase inhibition, it does not act on other enzyme in cell, therefore cell is not had toxic action, simultaneously it
Can also enter in intercellular substance, form intercellular colloid, play water conservation and increase the effect of skin elasticity；For mottle such as freckle,
The treatment of senile plaque, pigmentation and acne, whitening effect are fine.Simple emulsifying agent used for cosmetic is hardly at skin keratin
Layer leaves any chemical modification, and this kind of New-type emulsifier simply contacts with water and works, and lipid material is transported skin, reaches
Cleaning and the effect washed out.Spice possesses spectacular aromatic odor, body and mind of can releiving, treatment more soul, is that cosmetics are commonly used
Additive, safe and reliable.It is prevented effectively from the injury that skin is caused by the toxic and side effects of chemistry cosmetics, manufacturer
Method is simple, and speckle dispelling instant effect, treatment cycle is short, has no side effect, and does not damage skin of face, cheap, easy to use.Solve
The cosmetics infringement to skin of existing chemistry, and existing Chinese herbal medicine controls mottle to there is treatment cycle length, curative effect slow, produces
Complex process, the problem that manufacturing cost is high.
Detailed description of the invention
A kind of component-type freckle-removing beauty cream, it is characterised in that: this component-type freckle-removing beauty cream is made up of component A and B component,
Wherein:
Component A is made up of the raw material of following weight parts: Hirudo live body or Hirudo live body freeze product 1～10 parts；
B component is made up of the raw material of following weight parts: Periostracum Cicadae 1～10 parts, Periostracum Serpentis 1～10 parts, kojic acid 0.01～0.04 part, cosmetic
Product simple emulsifying agent 0.1～0.5 part, Fragrance qs.
Described component-type freckle-removing beauty cream is prepared from by following processing step:
1), hirudin is extracted:
Weigh Hirudo live body by component A weight portion or Hirudo live body freezes product, pulverize, add 5 times of normal saline, stirring
Extract 30 minutes, centrifugal, filter to obtain hirudin extracting solution；Membrane filtration hirudin extracting solution, removes the pigments such as residual hemoglobin,
After less than 4 DEG C cryoconcentration, average mark loads at least 30 cillin bottles, and lyophilizing obtains hirudin；
2) Periostracum Cicadae and Periostracum Serpentis concentrated solution are extracted:
Slightly carry: weigh Periostracum Cicadae and Periostracum Serpentis respectively by B component weight portion, Periostracum Cicadae and Periostracum Serpentis are cleaned, dry, pulverize, mix, add
Periostracum Cicadae and the pure water of Periostracum Serpentis gross weight ten times, be warming up to 100 DEG C, is cooled to 80 DEG C after keeping 2 minutes, keeps 80 DEG C of temperature, stirs
Mix extraction 2 hours, filter, waste.
Concentrate: the extracting solution concentrating under reduced pressure below 50 DEG C that will slightly raise, be concentrated into 1/the 20 of original volume；Continue
It is cooled to room temperature (25 DEG C), adds kojic acid, simple emulsifying agent used for cosmetic and spice, stir and i.e. prepare concentrated solution, subpackage
Stand-by.
The using method of described component-type freckle-removing beauty cream is as follows:
The first step: first use warm water cleaning skin, and apply face 3～5 minutes with hot towel, thoroughly to open pore；
Second step: take component A hirudin lyophilized powder, opens cillin bottle sealing, adds 3ml normal saline, rock dissolving；
3rd step: be applied to rapidly on the face by sufficient for dissolving hirudin solution, pats skin gently and fills by hirudin after smearing
Divide and absorb；
4th step: after face is the most dry, takes B component appropriate, and uniform application on the face, washes away after half an hour.
The concrete manufacturing process of this component-type freckle-removing beauty cream and preparation method is as follows:
Embodiment 1(every part is 50g):
Component A: weigh Hirudo or Hirudo freezes product 4 parts i.e. 200g, add 5 times i.e. 1000ml(1000g) normal saline,
Stir 30 minutes, filter to obtain hirudin extracting solution 900ml；The impurity such as membrane filtration removal hemoglobin, less than 4 DEG C cryoconcentration,
To be concentrated to stopping concentration during 200ml, gained stillness of night average mark is loaded in 30 cillin bottles, and lyophilizing i.e. obtains hirudin lyophilizing
Powder；
B component: weighing Periostracum Cicadae 2 parts is 100g and Periostracum Serpentis 1 part i.e. 50g, cleans with pure water and air-dries, pulverize, adds Periostracum Cicadae and Periostracum Serpentis
Gross weight ten times is 1500ml(1500g) pure water, heats up 100 DEG C, keeps 2 minutes, be cooled to 80 DEG C, keep 80 DEG C of stirrings to extract
2 hours, filter, obtain filtrate 1400ml, continue to be concentrated into 70ml and stop concentrating；Filtrate is cooled to room temperature (25 DEG C), adds song
Acid 0.02 part i.e. 1g and emulsifying agent 0.2 part are 10g(10ml), instill qs Fragrance, be uniformly mixed, i.e. obtain Periostracum Cicadae and Serpentis
Slough off concentrated solution, bottle standby.
Embodiment 2(every part is 50g):
Component A: weigh Hirudo freezing product 1 part is 50g, adds 5 times i.e. 250ml(250g) normal saline, stirs half an hour, mistake
Filtering to obtain hirudin extracting solution 240ml, membrane filtration removes the impurity such as hemoglobin, and less than 4 DEG C cryoconcentration are to be concentrated to 200ml
Time stop concentrate, in 30 cillin bottles of the gained stillness of night average subpackage, lyophilizing i.e. obtains hirudin lyophilized powder.(single bottle of hirudin contains
Amount is 1/4th of embodiment 1)
B component: weighing Periostracum Cicadae 1 part is 50g and Periostracum Serpentis 1 part i.e. 50g, cleans with pure water and air-dries, pulverize, adds Periostracum Cicadae and Periostracum Serpentis is total
Weight ten times is 1000g(1000ml) pure water, it is warming up to 100 DEG C, is incubated 2 minutes, is cooled to 80 DEG C, keep 80 DEG C of stirrings to extract
2 hours, filtering, obtain filtrate 900ml, filtrate continues to be concentrated into 45ml, is cooled to room temperature (25 DEG C), adds 0.01 part i.e. 0.5g bent
Acid and 0.1 part i.e. 5g(5ml) simple emulsifying agent used for cosmetic, instill qs Fragrance, be uniformly mixed and i.e. obtain Periostracum Cicadae and Serpentis
The concentrated solution sloughed off, bottles standby.
Embodiment 3(every part 50g):
Component A: weigh Hirudo freezing product 10 parts is 500g, adds 5 times i.e. 2500g(2500ml) normal saline, stirring half is little
Time, filtering to obtain hirudin extracting solution 2350ml, membrane filtration removes the impurity such as hemoglobin, when less than 4 DEG C cryoconcentration are to 300ml
Stopping concentrating, gained stillness of night average mark is loaded on lyophilizing in 60 cillin bottles, i.e. obtains hirudin lyophilized powder.(hirudin content ratio
Embodiment 1 is high by 16%)
B component: weighing Periostracum Cicadae 10 parts is 500g and Periostracum Serpentis 10 parts i.e. 500g, cleans with pure water and air-dries, pulverize, adds Periostracum Cicadae Periostracum Serpentis
Gross weight ten times is 10000g(10000ml) pure water, it is warming up to 100 DEG C, is incubated 2 minutes, is cooled to 80 DEG C, keep 80 DEG C of stirrings
Extracting 2 hours, filter, obtain filtrate 9000ml, filtrate continues to be concentrated into 450ml, is cooled to room temperature (25 DEG C), adds 0.04 part i.e.
2g kojic acid and 0.5 part i.e. 25g(25ml) emulsifying agent, instill qs Fragrance, be uniformly mixed and i.e. obtain the dense of Periostracum Cicadae and Periostracum Serpentis
Contracting liquid, bottle standby (for bimestrial consumption).
Using effect record:
User male, 48 years old, left and right face chloasma, use the failure of other cosmetics speckle dispelling, use this product January, chloasma disappears
Moving back, complexion is pale red, and the colour of skin is changed significantly.
User male, 32 years old, left and right face all had a freckle, used this product January, and freckle is significantly desalinated.
User women, 56 years old, rural females, it to be exposed to the sun throughout the year, brown partially that One's face was like wax in left and right, cheek speckle is obvious, uses
This product February, the colour of skin significantly highlights, the notable fading of cheek speckle, and change is clearly.
This component-type freckle-removing beauty cream and preparation method are the most notable by extracting activity from Hirudo and salivary gland thereof
Hirudin make hirudin lyophilized powder, can dredge and expand skin of face blood capillary, improve face microcirculation, improve corium
Blood microcirculation, promotes skin metabolism and melanocyte metabolism, can fundamentally solve mottle, comedo, scar print, red
All kinds of skin problem such as the blood streak, pigmentation.Manufacture method is simple, uses also very convenient, and freckle effect is good, instant effect.Very
Being suitable for facial colour spot patient to use, cost is low, not injured skin, safe and reliable.
The above is presently preferred embodiments of the present invention, and the flesh and blood of the present invention is not made by the example above explanation
Any pro forma restriction, person of an ordinary skill in the technical field is the technology of the foundation present invention after having read this specification
Any simple modification that above detailed description of the invention is made by essence or deformation, and the technology contents possibly also with the disclosure above
Changed or be modified to the Equivalent embodiments of equivalent variations, all still fallen within the range of technical solution of the present invention, without departing from
The spirit and scope of the invention.
Claims (3)
1. a component-type freckle-removing beauty cream, it is characterised in that: it is made up of component A and B component, wherein:
Component A is made up of the raw material of following weight parts: Hirudo live body or Hirudo live body freeze product 1～10 parts；
B component is made up of the raw material of following weight parts: Periostracum Cicadae 1～10 parts, Periostracum Serpentis 1～10 parts, kojic acid 0.01～0.04 part, cosmetic
Product simple emulsifying agent 0.1～0.5 part, Fragrance qs.
2. the preparation method for the component-type freckle-removing beauty cream described in claim 1, it is characterised in that: it is by such as
Lower processing step is prepared from:
1), hirudin is extracted:
Weigh Hirudo live body by component A weight portion or Hirudo live body freezes product, pulverize, add 5 times of normal saline, stirring
Extract 30 minutes, centrifugal, filter to obtain hirudin extracting solution；Membrane filtration hirudin extracting solution, removes the pigments such as residual hemoglobin,
After less than 4 DEG C cryoconcentration, average mark loads at least 30 cillin bottles, and lyophilizing obtains hirudin；
2) Periostracum Cicadae and Periostracum Serpentis concentrated solution are extracted:
Slightly carry: weigh Periostracum Cicadae and Periostracum Serpentis respectively by B component weight portion, Periostracum Cicadae and Periostracum Serpentis are cleaned, dry, pulverize, mix, add
Periostracum Cicadae and the pure water of Periostracum Serpentis gross weight ten times, be warming up to 100 DEG C, is incubated 2 minutes, is cooled to 80 DEG C, keeps 80 DEG C of temperature stirrings
Extract 2 hours, filter, waste；
Concentrate: the extracting solution concentrating under reduced pressure below 50 DEG C that will slightly raise, be concentrated into 1/the 20 of original volume；It is cooled to room
Temperature, adds kojic acid, simple emulsifying agent used for cosmetic and spice, stirs and i.e. prepare concentrated solution, bottle stand-by.
A kind of component-type freckle-removing beauty cream the most according to claim 1 and preparation method, it is characterised in that: described component
The using method of type freckle-removing beauty cream is as follows:
The first step: first use warm water cleaning skin, and apply face 3～5 minutes with hot towel, thoroughly to open pore；
Second step: take component A hirudin lyophilized powder, opens cillin bottle sealing, adds 3ml normal saline, rock dissolving；
3rd step: be applied to rapidly on the face by sufficient for dissolving hirudin solution, pats skin gently and fills by hirudin after smearing
Divide and absorb；
4th step: after face is the most dry, takes B component appropriate, and uniform application on the face, washes away after half an hour.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610914087.2A CN106265462B (en) | 2016-10-20 | 2016-10-20 | Component type spot-removing beauty cream and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610914087.2A CN106265462B (en) | 2016-10-20 | 2016-10-20 | Component type spot-removing beauty cream and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108653158A (en) * | 2017-03-27 | 2018-10-16 | 上海莱妃化妆品有限公司 | There are the cosmetics and preparation method of auxiliary repair to sensitive skin |
| CN109260046A (en) * | 2018-09-28 | 2019-01-25 | 重庆雅素生物科技有限公司 | Hirudin repairs application, composition and the preparation method of skin red capillary or hormone face |
| CN111249170A (en) * | 2020-04-01 | 2020-06-09 | 广州今盛美精细化工有限公司 | Hirudin and application thereof in preparation of cosmetics |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108653158A (en) * | 2017-03-27 | 2018-10-16 | 上海莱妃化妆品有限公司 | There are the cosmetics and preparation method of auxiliary repair to sensitive skin |
| CN109260046A (en) * | 2018-09-28 | 2019-01-25 | 重庆雅素生物科技有限公司 | Hirudin repairs application, composition and the preparation method of skin red capillary or hormone face |
| CN111249170A (en) * | 2020-04-01 | 2020-06-09 | 广州今盛美精细化工有限公司 | Hirudin and application thereof in preparation of cosmetics |
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| CN106265462B (en) | 2020-11-27 |
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