CN106265462B - Component type spot-removing beauty cream and preparation method thereof - Google Patents
Component type spot-removing beauty cream and preparation method thereof Download PDFInfo
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- CN106265462B CN106265462B CN201610914087.2A CN201610914087A CN106265462B CN 106265462 B CN106265462 B CN 106265462B CN 201610914087 A CN201610914087 A CN 201610914087A CN 106265462 B CN106265462 B CN 106265462B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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Abstract
The invention relates to a component type freckle-removing beauty cream and a preparation method thereof, belonging to the technical field of freckle-removing beauty skin care products. The medicament is prepared from a component A and a component B, wherein the component A comprises hirudin, periostracum cicadae, periostracum Serpentis, kojic acid and other raw materials in certain parts by weight. The hirudin has effects of dilating skin capillary, improving dermal blood microcirculation, promoting melanocyte metabolism, and promoting absorption by skin cells. The periostracum Serpentis and periostracum Cicadae can accelerate metabolism of skin surface cell and exfoliation of epidermal macula, and promote generation of new skin, and have effects of enhancing skin elasticity and eliminating mottle. Kojic acid has effects of retaining water and increasing skin elasticity, and has good therapeutic effect on mottle such as freckle and pigmentation. Simple preparation method, quick effect for removing speckle, short treatment period, no damage to facial skin, low cost, and convenient application. Solves the problems that the existing chemical freckle-removing cosmetics damage skin, and the existing traditional Chinese medicine for treating the freckles has long period, slow curative effect, complex production process and high manufacturing cost.
Description
Technical Field
The invention relates to a component type freckle-removing beauty cream and a preparation method thereof, belonging to the technical field of freckle-removing beauty skin care products.
Background
The pigmented spots are skin diseases caused by the increase of skin melanin, are frequently generated on the cheek and forehead of women, and freckles, cyasma, black spots and chloasma are collectively called the pigmented spots. The color spots not only affect the beauty of the patient, but also cause strong stimulation to the heart of the patient, and can cause pathological changes of organs of the patient to cause serious diseases after a long time. Therefore, no matter what about removing spots. Currently, spot-removing cosmetics on the market are various, but generally contain mercury, lead and hormone which damage the skin, and mostly adopt covering and 'thinning' skin modes to remove spots and whiten skin, have large toxic and side effects, are easy to cause skin dependence and anaphylactic reaction, and once the cosmetics are stopped, the skin can be dark and has scars, and some people even have red, swollen and ulcerated faces. The Chinese herbal medicine is used for treating the color spots, the damage of toxic and side effects of the chemical freckle-removing cosmetics to skin can be avoided, the use is safe and reliable, and the problems of long period, slow effect, complex production process and high manufacturing cost of the color spot treatment are also solved.
Disclosure of Invention
The invention aims to provide the component type freckle-removing beauty cream which has the advantages of simple manufacturing method, quick freckle-removing effect, short treatment period, no toxic or side effect, no damage to facial skin, low manufacturing cost and convenient use and the preparation method thereof aiming at the defects of the prior art.
The invention realizes the purpose through the following technical scheme:
a component type spot-removing beauty cream is characterized in that: it is composed of a component A and a component B, wherein:
the component A consists of the following raw materials in parts by weight: 1-10 parts of blood-sucking leech living bodies or frozen blood-sucking leech living bodies;
the component B comprises the following raw materials in parts by weight: 1-10 parts of cicada slough, 1-10 parts of snake slough, 0.01-0.04 part of kojic acid, 0.1-0.5 part of simple emulsifier for cosmetics and a proper amount of spice.
The component type spot-removing beauty cream is prepared by the following process steps:
1) and extracting hirudin:
weighing the leech living body or the frozen leech living body according to the weight part of the component A, crushing, adding 5 times of physiological saline, stirring and extracting for 30 minutes, centrifuging, and filtering to obtain a hirudin extracting solution; filtering hirudin extractive solution with membrane, removing pigment such as hemoglobin, concentrating at low temperature below 4 deg.C, packaging into 30 vials, and lyophilizing to obtain hirudin;
2) extracting a cicada slough and snake slough concentrated solution:
crude extraction: weighing the cicada slough and the snake slough according to the weight part of the component B, cleaning the cicada slough and the snake slough, airing, crushing, mixing, adding pure water which is ten times of the total weight of the cicada slough and the snake slough, heating to 100 ℃, keeping for 2 minutes, cooling to 80 ℃, keeping the temperature at 80 ℃, stirring and extracting for 2 hours, filtering, and removing residues;
concentration: concentrating the extractive solution at 50 deg.C under reduced pressure to 20 times of original volume; cooling to room temperature, adding kojic acid, simple emulsifier for cosmetics and perfume, stirring to obtain concentrated solution, and bottling.
The application method of the component type freckle-removing beauty cream comprises the following steps:
the first step is as follows: firstly, washing the skin with warm water, and applying a hot towel to the face for 3-5 minutes to thoroughly open pores;
the second step is that: taking the hirudin freeze-dried powder of the component A, opening a penicillin bottle for sealing, adding 3ml of normal saline, and shaking for dissolving;
the third step: quickly applying the fully dissolved hirudin solution to the face, and lightly beating the skin after application to ensure that the hirudin is fully absorbed;
the fourth step: after the face is slightly dry, taking a proper amount of the component B, uniformly coating the component B on the face, and washing after half an hour.
The efficacy of the component type spot-removing beauty cream and the preparation method of the cream are as follows:
hirudin: is one of the most significant and studied components extracted from leeches and their salivary glands. Hirudin is a small molecular protein (polypeptide) consisting of 65-66 amino acids. Hirudin has a very strong inhibitory effect on thrombin, and is the strongest natural specific thrombin inhibitor discovered so far. Animal experiments and clinical researches show that the hirudin can efficiently prevent coagulation and thrombosis, and prevent coagulation factor activation and platelet reaction catalyzed by thrombin from further blood stasis. In addition, hirudin inhibits thrombin-induced fibroblast proliferation and thrombin stimulation of endothelial cells. Compared with heparin, it has less consumption, no bleeding and no dependence on endogenous auxiliary factor.
Because the molecular weight of hirudin is extremely small (the molecular weight is 4000-7000 daltons), the hirudin has remarkable permeability and extremely strong effects of improving microcirculation and promoting metabolism, so the natural hirudin freeze-dried powder can dredge and expand facial skin capillaries, improve dermal blood microcirculation and promote melanocyte metabolism, quickly permeates into the deep layer of skin, and is easily absorbed by skin cells. On the other hand, hirudin has effects of dredging capillary vessel, improving facial microcirculation, promoting skin metabolism, and fundamentally solving various skin problems such as color spot, acne, scar, red blood streak, pigmentation, etc. The hirudin taken orally can also play a role in systemic regulation, and the functions almost relate to all physiological activities of the human body, such as: endocrine, digestive, absorptive, metabolic, growth, reproductive, and neural, among others. At the 21 st Guangzhou international beauty cosmetics exposition in 9.2004, hirudin is considered as the new product with the highest gold content in the technical society. The advent of hirudin cosmetics has marked the arrival of the hirudin cosmetic age.
Cicada slough: the name of the traditional Chinese medicine is completely like a cicada, is hollow and is slightly bent. Cicada slough is used as a medicine part: is molting shell of cicada insect after black locust emergence. Cicada slough is sweet, salty and cool in nature. Cicada slough enters lung and liver meridians. Periostracum Cicadae has effects of dispelling pathogenic wind and heat, relieving sore throat, promoting voice production, promoting eruption, improving eyesight, removing nebula, calming endogenous wind and relieving spasm. The cicada slough can accelerate the metabolism speed of skin surface cells, accelerate the shedding of epidermal spots and the generation of new skin, thereby achieving the purposes of enhancing the skin elasticity and eliminating the spots; meanwhile, the cicada slough also has the effects of relieving skin itch, relieving fever and resisting allergy.
Snake slough: the name of the traditional Chinese medicine. Is dried epidermal membrane of Elaphe carinata, Elaphe carinata or Zaocys of Colubridae. Collecting spring end and summer or winter, removing silt, and drying. Snake slough is salty, sweet and neutral in flavor. She tui enters liver meridian. Periostracum Serpentis has effects of dispelling pathogenic wind, arresting convulsion, removing nebula, and removing toxic substance. The main treatment of the snake slough is as follows: infantile convulsion, convulsion and spasm, nebula, pharyngitis, sore throat, swelling and skin pruritus. Ben Cao Jing Shu (the book of materia Medica Prime and Dredging): snake slough enters liver to avoid nausea, infantile convulsion, thorny elaeagnus, cold and heat, epilepsy attacking tongue and shaking head, adult five pathogens and speech are kept clear, liver meridian is all diseases, and the snake slough can induce various medicines to enter liver to dissipate pathogens, so the treatment is mainly for the first-class symptoms. It is good at killing parasites, so it is mainly indicated for intestinal hemorrhoids with noxious worm and malignant sores. Pathogenic factors can eliminate the pathogenic factors and reduce the adverse rise of qi, thus stopping vomiting, cough and improving eyesight. The periostracum Serpentis is the same as periostracum Cicadae, and has effects of accelerating metabolism speed of skin surface cell, accelerating exfoliation of epidermal macula and generation of new skin, enhancing skin elasticity, and eliminating macula; also has effects in relieving skin pruritus, relieving fever and resisting allergy.
Kojic acid: the chemical name is 5-hydroxy-2-hydroxymethyl-1, 4-pyrone. It is used in brewing soy sauce, bean paste and alcoholic beverage. The presence of kojic acid can be detected in many fermentation products fermented with aspergillus. Kojic acid is used in cosmetics and food processing. Kojic acid, also known as kojic acid and kojic acid, is a melanin-specific inhibitor, which can complex with copper ions in cells after entering skin cells, change the steric structure of tyrosinase, prevent the activation of tyrosinase, and thus inhibit the formation of melanin. The kojic acid whitening active agent has better tyrosinase inhibition effect than other whitening active agents. It has no action on other biological enzymes in cells, has no toxic action on cells, and can enter intercellular substance to form intercellular colloid, so as to retain water and increase skin elasticity. It has been formulated into various cosmetics to make whitening cosmetics against freckles, age spots, pigmentation, and acne.
Simple emulsifying agent for cosmetics: is a substance which promotes two mutually insoluble liquids to form a stable emulsion. The emulsifier has certain bacteriostatic action and is commonly used for resisting corrosion and keeping freshness of fruits. The emulsifier is used in cosmetics, and has the functions of solubilization, soaking, moistening, etc. besides emulsification. Cosmetic simple emulsifiers leave little chemical modification of the stratum corneum, and these new emulsifiers act only upon contact with water to transport lipid materials out of the skin for cleansing and washout.
The emulsifier used in food industry is sucrose fatty acid ester, lecithin, glycerol mono-citrate, soybean phospholipid, sorbitan fatty acid ester and dextrin. The emulsifier used in cosmetics is polyethylene oxide glycerin fatty acid ester, sorbitan polyethylene oxide tetraoleate, alkylphenol polyethylene oxide ether, sorbitol polyethylene oxide ether, etc.
Spice: is a substance which can smell fragrance by smell or taste and is a raw material for preparing essence. Fragrances are an important component of fine chemicals and consist of 3 parts, natural, synthetic and isolated fragrances. The spice has the advantages of attractive aromatic odor, body and mind relaxing and heart healing effects, is widely used in the industries of food, daily chemicals, tobacco, medicine and the like, and is closely related to the daily life of people. The plant natural perfume is essential oil, extract, tincture, balsam and absolute oil, etc. produced by using flower, branch, leaf, grass, root, bark, stem, seed or fruit, etc. of aromatic plant as raw material and through steam distillation, extraction, squeezing, absorption, etc., such as rose oil, jasmine extract, vanilla tincture, cabbage balsam, toluol resin, Narcissus chinensis, etc. The animal natural perfume is animal secretion or excretion. There are dozens of animal natural perfume, which can be made into commercial product and only 4 kinds of musk, ambergris, civet and castoreum are frequently used, and the tinctures are usually made with ethanol. Perfume and essence are widely used for perfumed soaps, detergents, various cosmetics such as cold creams, vanishing creams, hair waxes, shampoos, toilet water and perfumes, etc., skin-care cosmetics, toothpastes, air cleaners and bactericides, etc., environmental hygiene products such as candies, cookies, beverages, cigarettes, wines, soy milk, milk products, vegetable protein foods, and medicines, paper, plastics, leather, fabrics, etc.
Compared with the prior art, the invention has the beneficial effects that:
the component type spot-removing beauty cream is prepared by adopting a certain weight part of a component A as a raw material hirudin and a certain weight part of a component B as a raw material of cicada slough, snake slough, kojic acid, spice and a simple emulsifying agent for cosmetics through the process of the invention. The hirudin has effects of dredging and dilating facial skin capillary, improving dermal blood microcirculation, promoting melanocyte metabolism, and rapidly permeating into skin deep layer to be absorbed by skin cells. The periostracum Serpentis is the same as periostracum Cicadae, and has effects of accelerating metabolism speed of skin surface cell, accelerating exfoliation of epidermal macula and generation of new skin, enhancing skin elasticity, and eliminating macula; also has effects in relieving skin pruritus, relieving fever and resisting allergy. Compared with other whitening active agents, the kojic acid whitening active agent has better tyrosinase inhibition effect, does not act on other biological enzymes in cells, has no toxic action on the cells, can enter intercellular substance to form intercellular colloid, and plays roles in retaining water and increasing skin elasticity; has good whitening effect on treating stains such as freckles, age spots, pigmentation and acnes. Cosmetic simple emulsifiers leave little chemical modification in the stratum corneum, and these new emulsifiers act only in contact with water to transport lipid out of the skin for cleansing and washout. The perfume has attractive aromatic odor, can relieve the mind and body, and cure the heart, is a common additive for cosmetics, and is safe and reliable to use. The skin-care product effectively avoids the damage of toxic and side effects of chemical freckle-removing cosmetics to skin, has the advantages of simple preparation method, quick freckle-removing effect, short treatment period, no toxic or side effect, no damage to facial skin, low cost and convenient use. Solves the problems of the prior chemical freckle-removing cosmetics on skin damage and the problems of long treatment period, slow curative effect, complex production process and high manufacturing cost of the prior Chinese herbal medicine for treating the freckles.
Detailed Description
A component type spot-removing beauty cream is characterized in that: the component type freckle-removing beauty cream consists of a component A and a component B, wherein:
the component A consists of the following raw materials in parts by weight: 1-10 parts of blood-sucking leech living bodies or frozen blood-sucking leech living bodies;
the component B comprises the following raw materials in parts by weight: 1-10 parts of cicada slough, 1-10 parts of snake slough, 0.01-0.04 part of kojic acid, 0.1-0.5 part of simple emulsifier for cosmetics and a proper amount of spice.
The component type spot-removing beauty cream is prepared by the following process steps:
1) and extracting hirudin:
weighing the leech living body or the frozen leech living body according to the weight part of the component A, crushing, adding 5 times of physiological saline, stirring and extracting for 30 minutes, centrifuging, and filtering to obtain a hirudin extracting solution; filtering the hirudin extractive solution with membrane, removing pigment such as residual hemoglobin, concentrating at low temperature below 4 deg.C, averagely packaging into at least 30 vials, and lyophilizing to obtain hirudin;
2) extracting a cicada slough and snake slough concentrated solution:
crude extraction: weighing the cicada slough and the snake slough according to the weight part of the component B, cleaning the cicada slough and the snake slough, airing, crushing, mixing, adding pure water which is ten times of the total weight of the cicada slough and the snake slough, heating to 100 ℃, keeping for 2 minutes, cooling to 80 ℃, keeping the temperature at 80 ℃, stirring and extracting for 2 hours, filtering, and discarding residues.
Concentration: concentrating the extractive solution at 50 deg.C under reduced pressure to 20 times of original volume; cooling to room temperature (25 deg.C), adding kojic acid, simple emulsifier for cosmetics and perfume, stirring to obtain concentrated solution, and packaging.
The application method of the component type freckle-removing beauty cream comprises the following steps:
the first step is as follows: firstly, washing the skin with warm water, and applying a hot towel to the face for 3-5 minutes to thoroughly open pores;
the second step is that: taking the hirudin freeze-dried powder of the component A, opening a penicillin bottle for sealing, adding 3ml of normal saline, and shaking for dissolving;
the third step: quickly applying the fully dissolved hirudin solution to the face, and lightly beating the skin after application to ensure that the hirudin is fully absorbed;
the fourth step: after the face is slightly dry, taking a proper amount of the component B, uniformly coating the component B on the face, and washing after half an hour.
The specific preparation process of the component type spot-removing beauty cream and the preparation method is as follows:
example 1 (50 g per serving):
the component A comprises: weighing 4 parts of blood-sucking leech or blood-sucking leech jelly, namely 200g, adding 5 times of physiological saline, namely 1000ml (1000 g), stirring for 30 minutes, and filtering to obtain 900ml of hirudin extracting solution; filtering with membrane to remove impurities such as hemoglobin, concentrating at 4 deg.C below, stopping concentrating when the concentration reaches 200ml, packaging the obtained clear solution in 30 penicillin bottles, and lyophilizing to obtain hirudin lyophilized powder;
the component B comprises: weighing 2 parts of periostracum cicadae (100 g) and 1 part of periostracum Serpentis (50 g), washing with pure water, air drying, pulverizing, adding 1500ml (1500 g) of pure water ten times of the total weight of periostracum cicadae and periostracum Serpentis, heating to 100 deg.C, holding for 2 min, cooling to 80 deg.C, holding 80 deg.C, stirring and extracting for 2 hr, filtering to obtain 1400ml of filtrate, concentrating to 70ml, and stopping concentration; cooling the filtrate to room temperature (25 deg.C), adding kojic acid 0.02 part (1 g) and emulsifier 0.2 part (10 g) into the filtrate, adding appropriate amount of perfume dropwise, stirring, mixing to obtain periostracum Cicadae and periostracum Serpentis concentrated solution, and bottling.
Example 2 (50 g per serving):
the component A comprises: weighing 1 part of blood-sucking leech jelly, namely 50g, adding 5 times of 250ml (250 g) of normal saline, stirring for half an hour, filtering to obtain 240ml of hirudin extracting solution, filtering by a membrane to remove impurities such as hemoglobin, concentrating at a low temperature below 4 ℃, stopping concentrating when the concentration reaches 200ml, subpackaging the obtained clear solution in 30 penicillin bottles on average, and freeze-drying to obtain the hirudin freeze-dried powder. (Single bottle hirudin content one quarter of example 1)
The component B comprises: weighing 1 part of cicada slough, namely 50g, and 1 part of snake slough, namely 50g, washing with pure water, air-drying, crushing, adding 1000g (1000 ml) of pure water which is ten times of the total weight of the cicada slough and the snake slough, heating to 100 ℃, keeping the temperature for 2 minutes, cooling to 80 ℃, stirring and extracting for 2 hours at 80 ℃, filtering to obtain 900ml of filtrate, continuously concentrating the filtrate to 45ml, cooling to room temperature (25 ℃), adding 0.01 part, namely 0.5g of kojic acid and 0.1 part, namely 5g (5 ml) of simple emulsifier for cosmetics, dripping a proper amount of spice, stirring and mixing uniformly to obtain a concentrated solution of the cicada slough and the snake slough, and bottling for later use.
Example 3 (50 g per serving):
the component A comprises: weighing 10 parts of blood-sucking leech jelly, namely 500g, adding 5 times of 2500g (2500 ml) of normal saline, stirring for half an hour, filtering to obtain 2350ml of hirudin extracting solution, filtering by a membrane to remove impurities such as hemoglobin, stopping concentration when the concentration is reduced to 300ml at a low temperature below 4 ℃, and evenly packaging the obtained clear solution into 60 cillin bottles for freeze-drying to obtain the hirudin freeze-dried powder. (hirudin content 16% higher than in example 1)
The component B comprises: weighing 10 parts of cicada slough, namely 500g, and 10 parts of snake slough, namely 500g, washing with pure water, air-drying, crushing, adding 10000g (10000 ml) of pure water which is ten times of the total weight of the cicada slough and the snake slough, heating to 100 ℃, keeping the temperature for 2 minutes, cooling to 80 ℃, stirring and extracting for 2 hours at 80 ℃, filtering to obtain 9000ml of filtrate, continuously concentrating the filtrate to 450ml, cooling to room temperature (25 ℃), adding 0.04 part, namely 2g of kojic acid and 0.5 part, namely 25g (25 ml) of emulsifier, dripping a proper amount of spice, stirring and mixing uniformly to obtain a concentrated solution of the cicada slough and the snake slough, and bottling for later use (the dosage of two.
Recording the use effect:
the chloasma of the face of a male aged 48 years old or about faces of the male fails to be removed by using other cosmetics, and the chloasma is faded, the face is white and reddish and the skin color changes obviously after the male is used for one month.
The freckles are obviously faded after the product is used for one month in a male, 32 years old and the left face and the right face of the male.
The female of a user, 56 years old, rural female, insolate throughout the year, the left and right facial color is yellow and brown, the cheek spots are obvious, the color of the skin is obviously improved, the cheek spots are obviously faded by using the product in February, and the change is very obvious.
The hirudin freeze-dried powder is prepared by extracting hirudin with the most obvious activity from blood sucking leeches and salivary glands thereof, can dredge and expand capillary vessels of facial skin, improve facial microcirculation, improve dermal blood microcirculation, promote skin metabolism and melanocyte metabolism, and can fundamentally solve various skin problems such as color spots, whelks, scars, red blood streaks, pigmentation and the like. Simple preparation method, convenient use, good speckle removing effect and quick response. Is very suitable for patients with facial color spots, has low cost, does not damage skin, and is safe and reliable to use.
While the foregoing is directed to embodiments of the present invention, other and further embodiments of the invention may be devised without departing from the basic scope thereof, and the scope thereof is determined by the claims that follow.
Claims (2)
1. A component type spot-removing beauty cream is characterized in that: it is composed of a component A and a component B, wherein:
the component A is prepared from the following raw materials in parts by weight: 1-10 parts of blood-sucking leech living bodies or frozen blood-sucking leech living bodies;
the component B is prepared from the following raw materials in parts by weight: 1-10 parts of cicada slough, 1-10 parts of snake slough, 0.01-0.04 part of kojic acid, 0.1-0.5 part of simple emulsifying agent for cosmetics and a proper amount of spice;
the component type spot-removing beauty cream is prepared by the following process steps:
1) and extracting hirudin:
weighing the leech living body or the frozen leech living body according to the weight part of the component A, crushing, adding 5 times of physiological saline, stirring and extracting for 30 minutes, centrifuging, and filtering to obtain a hirudin extracting solution; filtering the hirudin extract with membrane, removing residual hemoglobin, concentrating at low temperature below 4 deg.C, averagely packaging into at least 30 vials, and lyophilizing to obtain hirudin;
2) extracting a cicada slough and snake slough concentrated solution:
crude extraction: weighing the cicada slough and the snake slough according to the weight part of the component B, cleaning the cicada slough and the snake slough, airing, crushing, mixing, adding pure water which is ten times of the total weight of the cicada slough and the snake slough, heating to 100 ℃, keeping the temperature for 2 minutes, cooling to 80 ℃, keeping the temperature at 80 ℃, stirring and extracting for 2 hours, filtering, and removing residues;
concentration: concentrating the extractive solution at 50 deg.C under reduced pressure to 20 times of original volume; cooling to room temperature, adding kojic acid, simple emulsifier for cosmetics and perfume, stirring to obtain concentrated solution, and bottling.
2. The spot-removing cosmetic cream of claim 1, which is characterized in that: the application method of the component type freckle-removing beauty cream comprises the following steps:
the first step is as follows: firstly, washing the skin with warm water, and applying a hot towel to the face for 3-5 minutes to thoroughly open pores;
the second step is that: taking the hirudin freeze-dried powder of the component A, opening a penicillin bottle for sealing, adding 3ml of normal saline, and shaking for dissolving;
the third step: quickly applying the fully dissolved hirudin solution to the face, and lightly beating the skin after application to ensure that the hirudin is fully absorbed;
the fourth step: after the face is slightly dry, taking a proper amount of the component B, uniformly coating the component B on the face, and washing after half an hour.
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| CN108653158A (en) * | 2017-03-27 | 2018-10-16 | 上海莱妃化妆品有限公司 | There are the cosmetics and preparation method of auxiliary repair to sensitive skin |
| CN109260046A (en) * | 2018-09-28 | 2019-01-25 | 重庆雅素生物科技有限公司 | Hirudin repairs application, composition and the preparation method of skin red capillary or hormone face |
| CN111249170A (en) * | 2020-04-01 | 2020-06-09 | 广州今盛美精细化工有限公司 | Hirudin and application thereof in preparation of cosmetics |
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|---|---|---|---|---|
| CN1522689A (en) * | 2003-09-12 | 2004-08-25 | 周维海 | Leech extract cosmetics and method for making same |
| CN1732897A (en) * | 2005-08-16 | 2006-02-15 | 周维海 | Face-beautifying skin-caring lotion with leech extract and its preparation process |
| KR20130028548A (en) * | 2011-09-09 | 2013-03-19 | 박수미 | Cosmetic composition for skin cell regeneration, anti-inflammation and skin calming effect, and preparing method thereof |
| CN104056062A (en) * | 2014-06-13 | 2014-09-24 | 周建国 | Externally applied medicine for whitening skin and removing freckles and scars |
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| CN106265462A (en) | 2017-01-04 |
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