CN106265339A - A kind of six hours high-efficiency moisturizing compositions and preparation thereof and application - Google Patents
A kind of six hours high-efficiency moisturizing compositions and preparation thereof and application Download PDFInfo
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- CN106265339A CN106265339A CN201610825805.9A CN201610825805A CN106265339A CN 106265339 A CN106265339 A CN 106265339A CN 201610825805 A CN201610825805 A CN 201610825805A CN 106265339 A CN106265339 A CN 106265339A
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- tremella
- herba dendrobii
- radix salviae
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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Abstract
The invention discloses a kind of six hours high-efficiency moisturizing compositions and its preparation method and application, said composition is made up of Tremella extract, Herba Dendrobii extract, Radix Salviae Miltiorrhizae extract, trehalose and glycerol.Said composition can be directly used for skin moisturizing, it is also possible to adds in cosmetics, is used for resisting scaly dry skin, plays the effect of moisturizing skin Caring.
Description
Technical field
The present invention relates to cosmetic field.More particularly, to a kind of six hours high-efficiency moisturizing compositions and preparation thereof and
Application.
Background technology
Skin is made up of epidermis, corium and subcutaneus adipose tissue, and every layer all contains moisture, and the number of moisture content of skin is
Skin is tender, plentiful, glossy and softness whether key, and infant moisture content of skin higher position seems delicate gloss, old fell
Skin because water content relatively low, so seem dry, wither flat, desquamation, and wrinkle even occurs.
Moisturizing is eternal theme, is to ensure that the essential condition of skin health, slow down aging, developmental research excellent performance
Wetting agent is the target that people seek assiduously.The most with age, skin moisture-keeping mechanism sustains damage, and skin histology is thin
Born of the same parents and intercellular moisture reduce, and when horny layer moisture drops to below 10%, skin will seem dry, lose bullet
Property, wrinkling, accelerate skin aging.On the other hand skin suffers the infringements such as sweltering heat, cold, wind, cleaning agent, ultraviolet radiation,
Top layer can become more to be dried.
The most how to keep the moisture of skin, reduce moisture loss particularly significant.Skin moisturizer is main in the market
Including sealer, hygroscopic agent, hydrophilic matrix, preventing light agent and some special adding ingredients；Glycerol is normally used as moisturizing ingredient,
Moisture-keeping cosmetics product is prepared by emulsifying technology after adding surfactant, spices and essence, preservative.Its shortcoming is in the near future
Research finds, glycerin components has certain inhibitory action for skin pore, reduces the breathability of skin, and surfactant,
The external additive such as spices and essence and preservative has certain stimulation to skin, and serious meeting causes the diseases such as skin allergy
Shape.Therefore, the moisture-keeping cosmetics of the Novel moisturizing composition without external additive becomes the emphasis of industry research and exploitation.
Traditional medicine is thought, xerosis cutis is lung renal dysfunction, water liquid metabolic imbalance, the most flourish skin of body fluid, Gu Run
Fu Zhi road is invigorating the lung and the kidney, nourishes body fluid.In Chinese medicine document, also there is the record of skin-moisturizing, skin, and compiled Chinese medicine beauty treatment
Prescription, is all described from theory into action.The effect of polysaccharide component has been illustrated by some modern studies in recent years, the height of polysaccharide
Degree water absorption and good film property perfectly combine and can reach good moistening effect, are the most gradually applied to skin and protect
Wet, and polysaccharide is also the main component contained by most edible fungi, these all find safely and effectively skin moisturizer for us
Bring the prospect of light.
Tremella is a kind of edible and medicinal fungi, containing materials such as abundant polysaccharide and protein.Tremella polysaccharide is the master of Tremella
Want active substance, including acid heteroglycan, neutral heteropolysaccharide., cell wall polysaccharide, extracellular polysaccharide and acidic oligomer sugar five classes.Tremella is many
Sugar has the different physiological roles such as raising body immunity, antitumor, defying age, blood sugar lowering and blood fat reducing；Tremella protein contains
There are 17 kinds of aminoacid, 3/4 be provided that in aminoacid necessary to human body.Tremella polysaccharide is with its abundant raw material sources, uniqueness
Biological function and good edible safety, in recent years in natural function food additive, Medicines and Health Product, dailyization
The fields such as cosmetic increasingly come into one's own, and have development prospect widely.
Summary of the invention
It is an object of the present invention to provide a kind of six hours high-efficiency moisturizing compositions, said composition can be directly used for skin
Skin moisturizing, it is also possible to for cosmetics, there is the effect of moisturizing skin Caring.
Further object is that and a kind of moisturizer containing above-mentioned composition or cosmetics are provided.
For reaching above-mentioned purpose, the present invention uses following technical proposals:
A kind of six hours high-efficiency moisturizing compositions, described compositions is extracted by Tremella extract, Herba Dendrobii extract, Radix Salviae Miltiorrhizae
Thing, trehalose and glycerol composition.
Preferably, for preparing Radix Salviae Miltiorrhizae and the sea of the Tremella of Tremella extract, the Herba Dendrobii of Herba Dendrobii extract, Radix Salviae Miltiorrhizae extract
Algae sugar, the mass ratio of glycerol are 2-5:1-2:1-2:1-5:1-5.
Preferably, for preparing Radix Salviae Miltiorrhizae and the sea of the Tremella of Tremella extract, the Herba Dendrobii of Herba Dendrobii extract, Radix Salviae Miltiorrhizae extract
Algae sugar, the mass ratio of glycerol are 3:1:1:4:1.
Preferably, Tremella extract, Herba Dendrobii extract and Radix Salviae Miltiorrhizae extract in described compositions are prepared by the following method
Obtain:
(1) it is that the Tremella of 2-5:1-2:1-2, Herba Dendrobii and Radix Salviae Miltiorrhizae mix, pulverize, put in extraction pot by mass ratio；To carrying
Take addition deionized water in tank, make the most size-reduced Tremella, Herba Dendrobii and Radix Salviae Miltiorrhizae be sufficiently spread out；
(2) the mixed liquor stirring in extraction pot being warmed up to 60 DEG C, the solution adding the industrial soda that concentration is 10wt% will
The pH value of mixed liquor is transferred to 8.5-9.0, then proceedes to stirring and is warming up to 90 DEG C, and mixed liquor starts reaction, every half an hour to carrying
Taking addition concentration in tank is the NaOH solution of 1wt%, makes the pH value of mixed liquor be maintained at 8.5-9.0, when consolidating in mixed liquor contains
Amount more than 0.3wt% time, stopped reaction, by containing described Tremella extract, Herba Dendrobii extract, Radix Salviae Miltiorrhizae extract mixed liquor quiet
Put 8-12h；
(3) supernatant formed after the mixed liquor containing described Tremella extract, Herba Dendrobii extract, Radix Salviae Miltiorrhizae extract being stood
Liquid, filters with diatomite filter, precoats perlite before filtering on described diatomite filter, then starts to filter,
Obtain after filtration containing described Tremella extract, Herba Dendrobii extract, the bright colourless liquid of clarification of Radix Salviae Miltiorrhizae extract.
The preparation method of above-mentioned six hours high-efficiency moisturizing compositions, the method comprises the steps:
(1) it is that the Tremella of 2-5:1-2:1-2, Herba Dendrobii and Radix Salviae Miltiorrhizae mix, pulverize, put in extraction pot by mass ratio；
(2) in extraction pot, add deionized water, make the most size-reduced Tremella, Herba Dendrobii and Radix Salviae Miltiorrhizae be sufficiently spread out；
(3) pH value of mixed liquor in regulation extraction pot, extracts at a temperature of 60-90 DEG C；
(4) mixed liquor after extracting is filtered, concentrates, sterilizing and fill, obtain containing described Tremella extract, stone
Dry measure used in former times extract, the mixed liquor of Radix Salviae Miltiorrhizae extract.
Preferably, step (3) specifically includes following steps:
Stirring the mixed liquor in extraction pot and be warmed up to 60 DEG C, the solution adding the industrial soda that concentration is 10wt% will mixing
The pH value of liquid is transferred to 8.5-9.0, then proceedes to stirring and is warming up to 90 DEG C, and mixed liquor starts reaction, every half an hour to extraction pot
Middle addition concentration is the NaOH solution of 1wt%, makes the pH value of mixed liquor be maintained at 8.5-9.0, when the solid content in mixed liquor is big
When 0.3wt%, stopped reaction, the mixed liquor containing described Tremella extract, Herba Dendrobii extract, Radix Salviae Miltiorrhizae extract is stood 8-
12h。
Preferably, step (4) described filtration specifically includes following steps:
Take shape after the mixed liquor containing described Tremella extract, Herba Dendrobii extract, Radix Salviae Miltiorrhizae extract in extraction pot stands
The supernatant become, filters with diatomite filter, precoats perlite, obtain after filtration before filtering on diatomite filter
Clarify bright colourless liquid.
Preferably, also include that adaptation step, described adaptation step are between step (4) described filtration and concentration:
By the bright colourless liquid of clarification that is filtrated to get in macroporous resin column is placed on material-compound tank, add that to account for filtrate total
The hydroxyethyl cellulose of quality 0.03wt%, is then adjusted to 5.0-6.0 by the pH value of filtrate.
Preferably, step (4) described concentration specifically includes following steps:
Filtrate after allotment is by volume concentrated into 1/4, after concentration, in concentrated solution, adds trehalose and glycerol,
The trehalose added and the gross mass of glycerol are 1-3:2-5 with the mass ratio of concentrated solution；Preferably, the trehalose of addition and glycerol
The mass ratio of gross mass and concentrated solution be 1:2；
Step (4) described sterilizing specifically comprises the steps:
Concentrated solution after adding trehalose and glycerol stir under the temperature conditions of 90 DEG C and is incubated 30min and carries out sterilizing and obtain
Liquid after sterilizing；
Step (4) described fill specifically includes following steps:
Liquid after sterilizing is cooled to less than 50 DEG C, adds preservative, be stirred for 20-30min and make preservative the most molten
After solution canned in bucket.
The application in cosmetics of the above-mentioned compositions for skin moisturizing, described cosmetics selected from moisture-keeping cosmetics,
There are the cosmetics of the no special class of long-acting moisture-keeping efficacy, there are the special defects cosmetics of moisture-keeping efficacy or there is moisture-keeping efficacy
Makeup cosmetic；
Described cosmetics include following form: color make-up, BB frost, fancy soap, cleansing milk, bath gel, toner/smoothing toner, skin protection curry,
Facial treatment milk, protective skin cream, essence, eye cream, facial film, aerosol or Sprayable.
Beneficial effects of the present invention is as follows:
The present invention will use water extraction active substance therein and formed with trehalose, glycerol after Tremella, Herba Dendrobii, Radix Salviae Miltiorrhizae mixing
Compositions, there is good moistening effect, this compositions can be directly as moisturizer, it is also possible to add cosmetics to
In, make cosmetics have effect of moisturizing skin Caring, help skin to resist in dry environments and be dried damage, make skin brilliance moisten
Pool；The present invention uses natural extracts to replace typical glycerol moisturizing ingredient；Without surfactant, preservative, balsamic
The compositions such as essence, to skin-friendly, are suitable for being used in various skin quality, and do not result in the allergy of skin；Product preparation need not
The emulsifying technology of Traditional makeup, the cosmetic gel that the fine proportioning only utilizing raw material mutual i.e. can stably be deposited produces
Product.
Accompanying drawing explanation
Fig. 1 is that tester uses the relative increment rate of moisture of skin after the skin care item of the compositions containing embodiment 1 preparation；
Fig. 2 is that tester uses the test of skin hydration rate after the skin care item of the compositions containing embodiment 1 preparation；
Fig. 3 be tester use containing embodiment 1 preparation compositions skin care item after moisture of skin scatter and disappear test；
Fig. 4 is that after tester uses the skin care item of the compositions containing embodiment 1 preparation, skin relative moisture scatters and disappears rate.
Detailed description of the invention
In order to be illustrated more clearly that the present invention, below in conjunction with preferred embodiment, the present invention is described further.Ability
Field technique personnel should be appreciated that following specifically described content is illustrative and be not restrictive, and should not limit this with this
The protection domain of invention.
The invention provides a kind of six hours high-efficiency moisturizing compositions, described compositions includes that Tremella extract, Herba Dendrobii carry
Take thing, Radix Salviae Miltiorrhizae extract, trehalose and glycerol；For preparing the Tremella of Tremella extract, the Herba Dendrobii of Herba Dendrobii extract, Radix Salviae Miltiorrhizae carry
Take the Radix Salviae Miltiorrhizae of thing, trehalose, the mass ratio of glycerol are 2-5:1-2:1-2:1-5:1-5.
The inventors found that by Tremella, Herba Dendrobii, Radix Salviae Miltiorrhizae mixing after with water extraction active substance therein and with sea
The compositions that algae sugar, glycerol are formed, has good moistening effect, and this compositions can be directly as moisturizer, it is possible to
To add in cosmetics, make cosmetics have effect of moisturizing skin Caring, help skin to resist in dry environments and be dried damage,
Skin brilliance is made to moisten；Cosmetics said herein can be moisture-keeping cosmetics, have the change of the no special class of long-acting moisture-keeping efficacy
Cosmetic, has the special defects cosmetics of moisture-keeping efficacy or has the makeup cosmetic of moisture-keeping efficacy；These cosmetics include with
Lower form: color make-up, BB frost, cleansing milk, bath gel, toner/smoothing toner, skin protection curry, facial treatment milk, protective skin cream, essence, eye cream, face
Film, aerosol or Sprayable.
Tremella, is again Tremella, is the famous food and medicament dual-purpose fungus of China, is the excellent tonic product of life lengthening, is the traditional Chinese medical science
Traditional " strengthening the body resistance " medicine.It is documented: Tremella have the kidney invigorating, lung moistening, promote the production of body fluid, many effects such as cough-relieving.Zhang Renan institute
Write described in " book on Chinese herbal medicine the poem solution property of medicine note ": this thing has the profit of Radix Ophiopogonis to tremble with fear without it, have Rhizoma Polygonati Odorati sweet and greasy without it, be lung moistening benefit
Cloudy is top grade, can match in excellence or beauty with Radix Ginseng, Cornu Cervi Pantotrichum, Nidus collocaliae, has preventing and treating cough due to lung-heat, the dryness of the lung anxious to cough, chronic cough itching of the throat, cough band blood, for a long time
Cough network to hinder hypochondriac pain, pain in the lung and gastritis, constipation, have blood in stool and effect of menoxenia.
Herba Dendrobii sweet in the mouth, cold nature, enter stomach, kidney channel, nourishing YIN and clearing away heat, lung moistening nourishing the stomach, strengthening the tendons and bones." China's pharmacy dictionary "
" specially growing the gas-liquid of lung stomach, gas-liquid is rushed prosperous, and kidney water is spontaneous, " says that he is good at YIN nourishing and the production of body fluid promoting, treats all diseases of Yin and fluid deficiency to claim it；Herba Dendrobii
Having the function of nourishing YIN and benefiting blood, Qing Dynasty's " property of medicine opinion " says that essence, nourishing stomach-YIN, physical strength profiting are amassed in Herba Dendrobii energy the kidney invigorating；Herba Dendrobii is contained within enriching
Polysaccharose substance, experiment prove dendrobium polysaccharide have strengthen immunologic function effect, peritoneal macrophage can be strengthened red to chicken
The phagocytic activity of cell；After human body enters middle age, owing to internal cloudy liquid reduces day by day, thus accelerate skin aging, make
Limit is black or crumple, Herba Dendrobii contains the lymphatic temperament of volume, has moist Nutrition to human body skin；Shennong's Herbal is by Herba Dendrobii
Being classified as and have the medicine that " make light of one's life by commiting suicide and prolong life " acts on, modern study shows, Herba Dendrobii contains various trace elements, these trace element pair
Good health and a long life in human body have close relationship, Herba Dendrobii to the anti-aging effects of human body than anti-ageing to human body of general medicine
Old effect is more extensive, more comprehensively.
Radix Salviae Miltiorrhizae bitter in the mouth, micro-pungent, cold nature；The heart, spleen, liver, the medicine of kidney blood system；Having blood circulation promoting and blood stasis dispelling, nourishing blood to tranquillize the mind, removing heat from blood disappears
Swollen effect；Also there is reinforcement myocardial contraction, improve cardiac function, coronary artery dilating, promote reparation and the regeneration of tissue.
Trehalose is pure natural saccharide, very safety and stability, all contains it in a lot of organisms, to the work in a lot of biologies
Property material has the effect come back to life, and is widely used in food and medicine industry, trehalose application on cosmetics be based on
Its holding cell viability with excellence and the characteristic of biomacromolecule activity；Skin Cell, especially epidermis cell high temperature,
Under the environment such as high and cold, dry, intensive ultraviolet radiation, easily dry out generation keratinization, and even death comes off and makes skin damage；
Trehalose can form one layer of special protecting film at cell surface layer in this case, and the mucus separated out from film is not only moistened
Skin Cell, also there is the function being radiate by external heat.Thus protect the skin will not be impaired；So trehalose quilt
It is owing to it has superpower holding cell viability and the characteristic of biomacromolecule activity for cosmetics, at high temperature, is dried, by force
Under the environment such as ultraviolet, one layer of special protecting film can be formed at cell surface layer, the original nutrition of skin and water can not only be kept
Point, moreover it is possible to nourishes rough skin cell.Skin sunburn can be avoided simultaneously, reduce melanin deposition, effective defying age.
And this natural saccharide of trehalose, it is present in many desert plants, when plant dries up, formation one layer is glassy
Substrate, protect its internal structure, until rainwater is come, plant can play " extremely " and demutation, substantial amounts of research and reality miraculously
Trampling and show, trehalose can protect epidermis cell membrane structure, activating cell effectively, nurses one's health skin, makes skin health nature, has bullet
Property.
Glycerol also has moisturizing skin care, soft skin of removing ornaments and formal dress, and moistens brothers, and effect that profit body is anti-drying.
Embodiment 1
A kind of six hours high-efficiency moisturizing compositions, said composition by Tremella extract, Herba Dendrobii extract, Radix Salviae Miltiorrhizae extract,
Trehalose and glycerol composition；For prepare the Tremella of Tremella extract, the Herba Dendrobii of Herba Dendrobii extract, Radix Salviae Miltiorrhizae extract Radix Salviae Miltiorrhizae with
Trehalose, the mass ratio of glycerol are 3:1:1:4:1.
According to above-mentioned formula proportion, preparation comprises the steps: for the method for the compositions of skin moisturizing
(1) it is that the Tremella of 3:1:1, Herba Dendrobii and Radix Salviae Miltiorrhizae mix, pulverize, put in extraction pot by mass ratio；
(2) in extraction pot, add appropriate amount of deionized water, be added to make the most size-reduced Tremella, Herba Dendrobii and Radix Salviae Miltiorrhizae fully soak
Profit is launched；
(3) the mixed liquor stirring in extraction pot being warmed up to 60 DEG C, addition concentration is that the sodium hydroxide solution of 10wt% will
The pH value of mixed liquor is transferred to 8.5-9.0, then proceedes to stirring and is warming up to 90 DEG C, and mixed liquor starts reaction, every half an hour to carrying
Taking addition concentration in tank is the NaOH solution of 1wt%, makes the pH value of mixed liquor be maintained at 8.5-9.0, when consolidating in mixed liquor contains
Amount more than 0.3wt% time, stopped reaction, by containing described Tremella extract, Herba Dendrobii extract, Radix Salviae Miltiorrhizae extract mixed liquor quiet
Put 10h；
(4) take after the mixed liquor containing Tremella extract, Herba Dendrobii extract, Radix Salviae Miltiorrhizae extract in extraction pot stands and formed
Supernatant, filter with diatomite filter, filter before on diatomite filter precoat perlite, obtain clear after filtration
Clear bright colourless liquid；
Bright for the clarification being filtrated to get colourless liquid is sequentially passed through two macroporous resin column and carries out ion exchange, then put
In material-compound tank, adding the hydroxyethyl cellulose (HEC) accounting for filtrate gross mass 0.03wt% in material-compound tank, adding concentration is
The NaOH solution of 1wt%, is adjusted to 5.0-6.0 by the pH value of filtrate；
The filtrate having adjusted pH value is by volume concentrated into 1/4, after concentration, in concentrated solution, adds trehalose and sweet
Oil, the trehalose of addition and the gross mass of glycerol are 1:2 with the mass ratio of concentrated solution, and trehalose is 1:3 with the mass ratio of glycerol；
Concentrated solution after adding trehalose and glycerol stirs insulation 30min under the temperature conditions of 90 DEG C and carries out sterilizing,
Obtain liquid after sterilizing；I.e. for the compositions of skin moisturizing；
Liquid after sterilizing is cooled to less than 50 DEG C, adds preservative, be stirred for 20-30min and make preservative the most molten
After solution canned in bucket.
Embodiment 2
A kind of six hours high-efficiency moisturizing compositions, said composition by Tremella extract, Herba Dendrobii extract, Radix Salviae Miltiorrhizae extract,
Trehalose and glycerol composition；For prepare the Tremella of Tremella extract, the Herba Dendrobii of Herba Dendrobii extract, Radix Salviae Miltiorrhizae extract Radix Salviae Miltiorrhizae with
Trehalose, the mass ratio of glycerol are 4:1:1:1:5:95.
According to above-mentioned formula proportion, preparation comprises the steps: for the method for the compositions of skin moisturizing
(1) it is that the Tremella of 4:1:1, Herba Dendrobii and Radix Salviae Miltiorrhizae mix, pulverize, put in extraction pot by mass ratio；
(2) in extraction pot, add appropriate amount of deionized water, be added to make the most size-reduced Tremella, Herba Dendrobii and Radix Salviae Miltiorrhizae fully soak
Profit is launched；
(3) the mixed liquor stirring in extraction pot being warmed up to 60 DEG C, adding the sodium carbonate liquor that concentration is 10wt% will mix
The pH value closing liquid is transferred to 8.5-9.0, then proceedes to stirring and is warming up to 90 DEG C, and mixed liquor starts reaction, every half an hour to extraction
Adding concentration in tank is the NaOH solution of 1wt%, makes the pH value of mixed liquor be maintained at 8.5-9.0, when the solid content in mixed liquor
During more than 0.3wt%, stopped reaction, the mixed liquor containing described Tremella extract, Herba Dendrobii extract, Radix Salviae Miltiorrhizae extract is stood
10h；
(4) take after the mixed liquor containing Tremella extract, Herba Dendrobii extract, Radix Salviae Miltiorrhizae extract in extraction pot stands and formed
Supernatant, filter with diatomite filter, filter before on diatomite filter precoat perlite, obtain clear after filtration
Clear bright colourless liquid；
Bright for the clarification being filtrated to get colourless liquid is sequentially passed through two macroporous resin column and carries out ion exchange, then put
In material-compound tank, adding the hydroxyethyl cellulose (HEC) accounting for filtrate gross mass 0.03wt% in material-compound tank, adding concentration is
The NaOH solution of 1wt%, is adjusted to 5.0-6.0 by the pH value of filtrate；
The filtrate having adjusted pH value is by volume concentrated into 1/4, after concentration, in concentrated solution, adds trehalose and sweet
Oil, the trehalose of addition and the gross mass of glycerol are 1:2 with the mass ratio of concentrated solution, and trehalose is 1:3 with the mass ratio of glycerol；
Concentrated solution after adding trehalose and glycerol stirs insulation 30min under the temperature conditions of 90 DEG C and carries out sterilizing,
Obtain liquid after sterilizing；I.e. for the compositions of skin moisturizing；
Liquid after sterilizing is cooled to less than 50 DEG C, adds preservative, be stirred for 20-30min and make preservative the most molten
After solution canned in bucket.
Embodiment 3
A kind of six hours high-efficiency moisturizing compositions, said composition by Tremella extract, Herba Dendrobii extract, Radix Salviae Miltiorrhizae extract,
Trehalose and glycerol composition；For prepare the Tremella of Tremella extract, the Herba Dendrobii of Herba Dendrobii extract, Radix Salviae Miltiorrhizae extract Radix Salviae Miltiorrhizae with
Trehalose, the mass ratio of glycerol are 3:1:2:5:2:90.
According to above-mentioned formula proportion, preparation comprises the steps: for the method for the compositions of skin moisturizing
(1) it is that the Tremella of 3:1:2, Herba Dendrobii and Radix Salviae Miltiorrhizae mix, pulverize, put in extraction pot by mass ratio；
(2) in extraction pot, add appropriate amount of deionized water, be added to make the most size-reduced Tremella, Herba Dendrobii and Radix Salviae Miltiorrhizae fully soak
Profit is launched；
(3) the mixed liquor stirring in extraction pot being warmed up to 60 DEG C, addition concentration is that the sodium bicarbonate solution of 10wt% will
The pH value of mixed liquor is transferred to 8.5-9.0, then proceedes to stirring and is warming up to 90 DEG C, and mixed liquor starts reaction, every half an hour to carrying
Taking addition concentration in tank is the NaOH solution of 1wt%, makes the pH value of mixed liquor be maintained at 8.5-9.0, when consolidating in mixed liquor contains
Amount more than 0.3wt% time, stopped reaction, by containing described Tremella extract, Herba Dendrobii extract, Radix Salviae Miltiorrhizae extract mixed liquor quiet
Put 10h；
(4) take after the mixed liquor containing Tremella extract, Herba Dendrobii extract, Radix Salviae Miltiorrhizae extract in extraction pot stands and formed
Supernatant, filter with diatomite filter, filter before on diatomite filter precoat perlite, obtain clear after filtration
Clear bright colourless liquid；
Bright for the clarification being filtrated to get colourless liquid is sequentially passed through two macroporous resin column and carries out ion exchange, then put
In material-compound tank, in material-compound tank, add the hydroxyethyl cellulose (HEC) accounting for filtrate gross mass 0.03wt%, adding concentration be
The NaOH solution of 1wt%, is adjusted to 5.0-6.0 by the pH value of filtrate；
The filtrate having adjusted pH value is by volume concentrated into 1/4, after concentration, in concentrated solution, adds trehalose and sweet
Oil, the trehalose of addition and the gross mass of glycerol are 1:2 with the mass ratio of concentrated solution, and trehalose is 1:3 with the mass ratio of glycerol；
Concentrated solution after adding trehalose and glycerol stirs insulation 30min under the temperature conditions of 90 DEG C and carries out sterilizing,
Obtain liquid after sterilizing；I.e. for the compositions of skin moisturizing；
Liquid after sterilizing is cooled to less than 50 DEG C, adds preservative, be stirred for 20-30min and make preservative the most molten
After solution canned in bucket.
Embodiment 4
The present invention is for the skin performance of keeping humidity experiment of the compositions of skin moisturizing
Select 30 volunteers (between age 25-45 year, men and women does not limits), respectively inside arm at wrist 5cm with
A, B two region chosen by machine；The curry of the moisture-keeping composition prepared containing 5.0wt% embodiment 1 is uniformly smeared in a-quadrant, used
Curry mastic based on formula without any moisturizing ingredient.With B district as blank, carry out moisturizing evaluation:
1. use the skin of curry of the moisture-keeping composition containing 5.0wt% embodiment 1 preparation at 6 hours interior skin beauty waters
Split-phase is to increment rate；Relatively increment rate refer to the water-retention value of skin after sample with unused before the numerical value that shows of the ratio of numerical value
For adding how many；The standard of test is cosmetic industry standard QB/T 4256.
Result, as it is shown in figure 1, test result shows, employs the moisture-keeping composition containing 5.0% embodiment 1 preparation
The water retention of the skin area of curry is higher than not having to use the skin of the curry of the moisture-keeping composition containing 5.0% embodiment 1 preparation
The water retention in region, the curve explanation in Fig. 1 has in 6 hours mixed with the cosmetics of the moisture-keeping composition of embodiment 1 preparation
Significantly continue moisturizing effect.
2. the skin using the curry of the moisture-keeping composition containing 5.0wt% embodiment 1 preparation is locked at 6 hours interior skin
Water effect；The standard of test is cosmetic industry standard QB/T 4256.
Result, as in figure 2 it is shown, test result shows, employs the moisture-keeping composition containing 5.0% embodiment 1 preparation
The lock water effect of the skin area of curry is higher than not having to use the skin of the curry of the moisture-keeping composition containing 5.0% embodiment 1 preparation
The lock water effect in skin region, the cosmetics of the moisture-keeping composition that the curve explanation in Fig. 2 is prepared mixed with embodiment 1 are in 6 hours
There is significantly lock water effect.
3. use the skin of curry of the moisture-keeping composition containing 5.0wt% embodiment 1 preparation at 6 hours interior skin beauty waters
Test is lost in dispersion；
The standard of test is cosmetic industry standard QB/T 4256.
Result, as it is shown on figure 3, test result shows, employs the moisture-keeping composition containing 5.0% embodiment 1 preparation
The lock water effect of the skin area of curry is higher than not having to use the skin of the curry of the moisture-keeping composition containing 5.0% embodiment 1 preparation
The lock water effect in skin region, the cosmetics of the moisture-keeping composition that the curve explanation in Fig. 2 is prepared mixed with embodiment 1 are in 6 hours
There is significantly lock water effect.
4. use the skin phase that the skin of the curry of the moisture-keeping composition containing 5.0wt% embodiment 1 preparation is interior at 6 hours
To moisture loss rate；The skin relative moisture rate of scattering and disappearing refers to this time point of numerical value of being measured by instrument and a upper time point
The result of numerical value contrast；The standard of test is cosmetic industry standard QB/T 4256.
As shown in Figure 4, test result shows result, employs the moisture-keeping composition containing 5.0wt% embodiment 1 preparation
The lock water effect of the skin area of curry is higher than not having to use the curry of the moisture-keeping composition containing 5.0wt% embodiment 1 preparation
The lock water effect of skin area, the curve explanation in Fig. 2 is little 6 mixed with the cosmetics of the moisture-keeping composition of embodiment 1 preparation
Time interior there is significantly lock water effect.
Embodiment 5
With embodiment 1, embodiment 2, embodiment 3, the compositions prepared carries out contrast experiment.
Experimental technique
For simulated skin state, select the microscope slide of 21 × 80mm, stick adhesive tape.Compositions is configured to certain density
Aqueous solution, weighs the aqueous solution of about 100mg, by its uniform application on microscope slide, puts into the instrument of constant temperature and humidity；This experiment
Carry out under room temperature (25 DEG C), use saturated ammonium sulfate solution to control the constant humidity environment of 80%；Certain time (20,40,
60,100,200 minutes) after weigh, calculate sample moisturizing rate, moisturizing rate the biggest expression moistening effect is the best.Experimental result is such as
Shown in table 1.
Moisturizing rate (%)=1-(b-c)/(b-a) × 100%；
A microscope slide weight (g)；
B places front gross weight (g) after smearing；
C smear after place after gross weight (g)；
Table 1
These results suggest that, combination prepared by the present invention has good moisture-keeping efficacy, it has been found that when trehalose and sweet
When the mass ratio of oil is 4:1, the moistening effect of compositions is best, additionally, the matter of Tremella, Herba Dendrobii, Radix Salviae Miltiorrhizae, trehalose, glycerol, water
Amount ratio, the when of being then 3:1:1:4:1:100, has best moistening effect.
Obviously, the above embodiment of the present invention is only for clearly demonstrating example of the present invention, and is not right
The restriction of embodiments of the present invention, for those of ordinary skill in the field, the most also may be used
To make other changes in different forms, cannot all of embodiment be given exhaustive here, every belong to this
What bright technical scheme was extended out obviously changes or changes the row still in protection scope of the present invention.
Claims (10)
1. six hours high-efficiency moisturizing compositions, it is characterised in that: described compositions by Tremella extract, Herba Dendrobii extract and
Radix Salviae Miltiorrhizae extract, trehalose, glycerol form.
Six hours the most according to claim 1 high-efficiency moisturizing compositions, it is characterised in that: for preparing Tremella extract
Tremella, the Herba Dendrobii of Herba Dendrobii extract, the Radix Salviae Miltiorrhizae of Radix Salviae Miltiorrhizae extract are 2-5:1-2:1-2:1-5 with trehalose, the mass ratio of glycerol:
1-5。
Six hours the most according to claim 1 high-efficiency moisturizing compositions, it is characterised in that: for preparing Tremella extract
Tremella, the Herba Dendrobii of Herba Dendrobii extract, the Radix Salviae Miltiorrhizae of Radix Salviae Miltiorrhizae extract are 3:1:1:4:1 with trehalose, the mass ratio of glycerol.
Six hours the most according to claim 1 high-efficiency moisturizing compositions, it is characterised in that: the Tremella in described compositions carries
Take thing, Herba Dendrobii extract and Radix Salviae Miltiorrhizae extract to prepare by the following method:
(1) it is that the Tremella of 2-5:1-2:1-2, Herba Dendrobii and Radix Salviae Miltiorrhizae mix, pulverize, put in extraction pot by mass ratio；To extraction pot
Middle addition deionized water, makes the most size-reduced Tremella, Herba Dendrobii and Radix Salviae Miltiorrhizae be sufficiently spread out；
(2) the mixed liquor stirring in extraction pot being warmed up to 60 DEG C, the solution adding the industrial soda that concentration is 10wt% will mixing
The pH value of liquid is transferred to 8.5-9.0, then proceedes to stirring and is warming up to 90 DEG C, and mixed liquor starts reaction, every half an hour to extraction pot
Middle addition concentration is the NaOH solution of 1wt%, makes the pH value of mixed liquor be maintained at 8.5-9.0, when the solid content in mixed liquor is big
When 0.3wt%, stopped reaction, the mixed liquor containing described Tremella extract, Herba Dendrobii extract, Radix Salviae Miltiorrhizae extract is stood 8-
12h；
(3) supernatant formed after the mixed liquor containing described Tremella extract, Herba Dendrobii extract, Radix Salviae Miltiorrhizae extract being stood,
Filter with diatomite filter, on described diatomite filter, before filtering, precoat perlite, then start to filter, filter
After obtain containing described Tremella extract, Herba Dendrobii extract, the bright colourless liquid of clarification of Radix Salviae Miltiorrhizae extract.
The preparation method of six hours the most as claimed in claim 1 high-efficiency moisturizing compositions, it is characterised in that described method includes
Following steps:
(1) it is that the Tremella of 2-5:1-2:1-2, Herba Dendrobii and Radix Salviae Miltiorrhizae mix, pulverize, put in extraction pot by mass ratio；
(2) in extraction pot, add deionized water, make the most size-reduced Tremella, Herba Dendrobii and Radix Salviae Miltiorrhizae be sufficiently spread out；
(3) pH value of mixed liquor in regulation extraction pot, extracts at a temperature of 60-90 DEG C；
(4) mixed liquor after extracting is filtered, concentrates, sterilizing and fill, obtain carrying containing described Tremella extract, Herba Dendrobii
Take the mixed liquor of thing, Radix Salviae Miltiorrhizae extract.
Preparation method the most according to claim 5, it is characterised in that step (3) specifically includes following steps:
Mixed liquor in extraction pot is stirred and is warmed up to 60 DEG C, add the aqueous slkali that concentration is 10wt% and the pH value of mixed liquor is adjusted
To 8.5-9.0, then proceeding to stirring and be warming up to 90 DEG C, mixed liquor starts reaction, adds concentration every half an hour in extraction pot
For the NaOH solution of 1wt%, the pH value of mixed liquor is made to be maintained at 8.5-9.0, when the solid content in mixed liquor is more than 0.3wt%
Time, stopped reaction, the mixed liquor containing described Tremella extract, Herba Dendrobii extract, Radix Salviae Miltiorrhizae extract is stood 8-12h.
Preparation method the most according to claim 5, it is characterised in that step (4) described filtration specifically includes following steps:
Take formation after the mixed liquor containing described Tremella extract, Herba Dendrobii extract, Radix Salviae Miltiorrhizae extract in extraction pot stands
Supernatant, filters with diatomite filter, precoats perlite, obtain after filtration before filtering on described diatomite filter
Clarify bright colourless liquid.
Preparation method the most according to claim 5, it is characterised in that also include between step (4) described filtration and concentration
Adaptation step, described adaptation step is:
By the bright colourless liquid of clarification that is filtrated to get in macroporous resin column is placed on material-compound tank, add and account for filtrate gross mass
The hydroxyethyl cellulose of 0.03wt%, is then adjusted to 5.0-6.0 by the pH value of filtrate.
Preparation method the most according to claim 5, it is characterised in that step (4) described concentration specifically includes following steps:
Filtrate after allotment is by volume concentrated into 1/4, after concentration, in concentrated solution, adds trehalose and glycerol, add
Trehalose and the gross mass of glycerol and the mass ratio of concentrated solution be 1-3:2-5；Preferably, the trehalose of addition and glycerol is total
Quality is 1:2 with the mass ratio of concentrated solution；
Step (4) described sterilizing specifically comprises the steps:
Concentrated solution after adding trehalose and glycerol stir under the temperature conditions of 90 DEG C and is incubated 30min and carries out sterilizing and gone out
Liquid after bacterium；
Step (4) described fill specifically includes following steps:
Liquid after sterilizing is cooled to less than 50 DEG C, adds preservative, be stirred for after 20-30min makes preservative fully dissolve
Canned in bucket.
The application in cosmetics of six hours the most as claimed in claim 1 high-efficiency moisturizing compositions, it is characterised in that: described
Cosmetics are selected from moisture-keeping cosmetics, have the cosmetics of the no special class of long-acting moisture-keeping efficacy, have the special defects of moisture-keeping efficacy
Cosmetics or there is the makeup cosmetic of moisture-keeping efficacy；
Described cosmetics include following form: color make-up, BB frost, fancy soap, cleansing milk, bath gel, toner/smoothing toner, skin protection curry, skin protection
Emulsion, protective skin cream, essence, eye cream, facial film, aerosol or Sprayable.
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| CN114642613A (en) * | 2020-12-17 | 2022-06-21 | 太和康美(北京)中医研究院有限公司 | Jelly mask and preparation process thereof |
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| CN113616546A (en) * | 2021-07-14 | 2021-11-09 | 上海加新生物科技有限公司 | Peach resin polysaccharide gum capable of brightening skin, application and extraction preparation method thereof |
| CN113616546B (en) * | 2021-07-14 | 2024-02-02 | 上海加新生物科技有限公司 | Peach resin polysaccharide gum capable of brightening skin, application and extraction preparation method thereof |
| CN114276470A (en) * | 2021-12-28 | 2022-04-05 | 亿利耐雀生物科技有限公司 | Dendrobium polysaccharide and preparation method and application thereof |
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