CN103565722B - The combination of aurantialba extract and Tremella extract application in cosmetics - Google Patents
The combination of aurantialba extract and Tremella extract application in cosmetics Download PDFInfo
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Abstract
The invention discloses the combination of aurantialba extract and the Tremella extract application in cosmetics, described cosmetics are selected from: moisture-keeping cosmetics, have the anti-inflammatory cosmetics of moisture-keeping efficacy, have the anti-aging cosmetics of moisture-keeping efficacy or have the skin-lightening cosmetic of moisture-keeping efficacy.The combination of aurantialba extract and Tremella extract has moisture-keeping efficacy, can be directly used for skin moisture-keeping, it is possible to joins in cosmetics as functional additive and uses.
Description
Technical field
The present invention relates to field of natural medicinal chemistry and cosmetic field, be specifically related to a kind of aurantialba extract for moisturizing and the combination of Tremella extract, its preparation method and the application in cosmetics thereof.The invention still further relates to comprise the cosmetic composition of the combination of aurantialba extract and Tremella extract.
Background technology
Skin is made up of epidermis, corium and subcutaneus adipose tissue, and every layer all contains moisture.The number of moisture content of skin is the key that whether soft skin is tender, plentiful, glossy Yu.Infant moisture content of skin amount higher position seems delicate gloss, old people's skin because water content is relatively low, so seem dry, wither flat, desquamation, and wrinkle even occurs.
Moisturizing is eternal theme, is to ensure that the essential condition of skin health, slow down aging, the wetting agent of developmental research excellent performance are the targets that people seek assiduously.
On the one hand the most with age, skin moisture-keeping mechanism sustains damage, and skin tissue cell and intercellular moisture reduce, when horny layer moisture drops to below 10%, skin will seem dry, follows the string, wrinkling, accelerate skin aging.On the other hand skin suffers the infringements such as sweltering heat, cold, wind, cleaning agent, ultraviolet radiation, and top layer can become more to be dried.The most how to keep the moisture of skin, reduce moisture loss particularly significant.Skin moisturizer mainly includes sealer, hygroscopic agent, hydrophilic matrix, preventing light agent and some special adding ingredients in the market.
Traditional medicine is thought, xerosis cutis is lung renal dysfunction, water liquid metabolic imbalance, the most flourish skin of body fluid, therefore the road of skin moistening is invigorating the lung and the kidney, nourishes body fluid.In Chinese medicine document, also there is the record of skin-moisturizing, skin, and compiled Chinese medicine beauty treatment prescription, be all described from theory into action.The effect of polysaccharide component has been illustrated by some modern studies in recent years, the high water absorbing ability of polysaccharide and good film property perfectly combine and can reach good moistening effect, the most gradually it is applied to skin moisture-keeping, and polysaccharide is also the main component contained by most edible fungi, these are all found safely and effectively skin moisturizer for us and bring the prospect of light.
China's Chinese medicine aboundresources, finds superior moisturizing additive for us and provides the foundation.Ancient medical book is recorded: Tremella aurantialba Bandoni et Zang, and sweet in the mouth, property are flat, YIN nourishing, lung moistening, promote the production of body fluid, supplementing the brain；Cure mainly cough due to consumptive disease, hemoptysis, pulmonary tuberculosis.Tremella aurantialba Bandoni et Zang (TremellaaurantialbaBandonietZang), for Mycophyta door fungus, also known as Tremella mesenterica Retz ex Fr., cyclopentadienyl Ruo Seerbu (Tibetan language), golden yellow Tremella, yellow ear, brain ear.Tremella aurantialba Bandoni et Zang is a kind of Tibetan medicine, cures mainly Pulmonary Diseases.Tremella aurantialba Bandoni et Zang contains golden fungus polysaccharides, various aminoacid, vitamin B group etc..Modern medicine research shows: Tremella aurantialba Bandoni et Zang is improved function of nervous system, regulation body cell physiologically active, blood fat reducing, the liver protecting, raising hemopoietic function, improves the effects such as immunity.Tremella aurantialba Bandoni et Zang is a kind of edible fungi more precious than Tremella, and because yielding poorly, expensive, application person is less, knows that its person is the most less.
Tremella, is again Tremella, is the famous food and medicament dual-purpose fungus of China, is the excellent tonic product of life lengthening, is " strengthening the body resistance " medicine that the traditional Chinese medical science is traditional.It is documented: Tremella have the kidney invigorating, lung moistening, promote the production of body fluid, many effects such as cough-relieving.Written by Zhang Renan described in " book on Chinese herbal medicine poem solution property of medicine note ": this thing has the profit of Radix Ophiopogonis to tremble with fear without it, have Rhizoma Polygonati Odorati sweet and greasy without it, it is the top grade of lung moistening nourishing YIN, can match in excellence or beauty with Radix Ginseng, Cornu Cervi Pantotrichum, Nidus collocaliae, have preventing and treating cough due to lung-heat, the dryness of the lung anxious to cough, chronic cough itching of the throat, cough band blood, chronic cough network are hindered hypochondriac pain, pain in the lung and gastritis, constipation, had blood in stool and effect of menoxenia.
The present invention by the combination application of aurantialba extract and Tremella extract in cosmetics, it is provided that moisture-keeping efficacy, help skin resist dry environment, prevent moisture loss, moisturizing skin Caring.
Summary of the invention
It is an object of the invention to provide a kind of aurantialba extract with moisture-keeping function and the combination of Tremella extract, can be directly used for skin moisture-keeping.The combination of aurantialba extract and Tremella extract also can join in cosmetics as functional additive and use.
The combination of aurantialba extract and Tremella extract has moisture-keeping efficacy, it is possible to helps skin to resist in dry environments and is dried damage.The combination of aurantialba extract and Tremella extract is used for cosmetics, there is the effect of moisturizing skin Caring, make skin brilliance moisten.
Tremella aurantialba Bandoni et Zang and Tremella are applied to food and medicine field mostly at present.But, the present inventor finds through research, and the combination of aurantialba extract and Tremella extract also has skin Caring effect of brilliance, it is possible to resist the moisture loss under dry environment, to reach moisture-keeping efficacy.
Therefore, it is an object of the present invention to provide the combination of aurantialba extract and the Tremella extract application in cosmetics.Specifically, the application in the cosmetics of moisturizing is being prepared in the combination that it is an object of the invention to provide aurantialba extract and Tremella extract.
One according to the present invention preferred embodiment, and described cosmetics can be selected from: moisture-keeping cosmetics, has the anti-inflammatory cosmetics of moisture-keeping efficacy, has the anti-aging cosmetics of moisture-keeping efficacy or has the skin-lightening cosmetic of moisture-keeping efficacy.
One according to the present invention preferred embodiment, and described cosmetics can be to be following form: fancy soap, cleansing milk, bath gel, toner/smoothing toner, skin protection curry, facial treatment milk, protective skin cream, essence, eye cream, facial film, aerosol or Sprayable.
One according to the present invention preferred embodiment, and described cosmetics also comprise the acceptable adjuvant of cosmetic field.One according to the present invention preferred embodiment, the acceptable adjuvant of described cosmetic field is selected from: solvent, solubilizing agent, preservative, antioxidant, pH adjusting agent, penetrating agent, liposome, wetting agent, thickening agent, chelating agen, skinfeel regulator, surfactant, emulsifying agent, propelling/propellant, essence, pigment, and other functional additives.
According in the preferred embodiment of the present invention, during use, in the combination of described aurantialba extract and Tremella extract, the concentration of aurantialba extract is at least 0.001mg/ml, at least 0.01mg/ml, at least 0.015mg/ml, the concentration of Tremella extract is at least 0.001mg/ml, at least 0.01mg/ml, at least 0.015mg/ml.According in the preferred embodiment of the present invention, during use, in the combination of described aurantialba extract and Tremella extract, the concentration of aurantialba extract is at most 50mg/ml, at most 40mg/ml, at most 30mg/ml, at most 20mg/ml, at most 10mg/ml, at most 5mg/ml, at most 3mg/ml, at most 2mg/ml, at most 1.5mg/ml, the concentration of Tremella extract is at most 50mg/ml, at most 40mg/ml, at most 30mg/ml, at most 20mg/ml, at most 10mg/ml, at most 5mg/ml, at most 3mg/ml, at most 2mg/ml, at most 1.5mg/ml.Such as, in one preferred embodiment, during use, in the combination of described aurantialba extract and Tremella extract, the concentration of aurantialba extract is 0.001mg/ml to 50mg/ml, and the concentration of Tremella extract is 0.001mg/ml to 50mg/ml.In one preferred embodiment, during use, in the combination of described aurantialba extract and Tremella extract, the concentration of aurantialba extract is 0.01mg/ml to 40mg/ml, and the concentration of Tremella extract is 0.01mg/ml to 40mg/ml.In one preferred embodiment, during use, in the combination of described aurantialba extract and Tremella extract, the concentration of aurantialba extract is 0.01mg/ml to 30mg/ml, and the concentration of Tremella extract is 0.01mg/ml to 30mg/ml.In one preferred embodiment, during use, in the combination of described aurantialba extract and Tremella extract, the concentration of aurantialba extract is 0.01mg/ml to 20mg/ml, and the concentration of Tremella extract is 0.01mg/ml to 20mg/ml.In one preferred embodiment, during use, in the combination of described aurantialba extract and Tremella extract, the concentration of aurantialba extract is 0.015mg/ml to 10mg/ml, and the concentration of Tremella extract is 0.015mg/ml to 10mg/ml.In one preferred embodiment, during use, in the combination of described aurantialba extract and Tremella extract, the concentration of aurantialba extract is 0.015mg/ml to 5mg/ml, and the concentration of Tremella extract is 0.015mg/ml to 5mg/ml.In one preferred embodiment, during use, in the combination of described aurantialba extract and Tremella extract, the concentration of aurantialba extract is 0.015mg/ml to 2mg/ml, and the concentration of Tremella extract is 0.015mg/ml to 2mg/ml.In one preferred embodiment, during use, in the combination of described aurantialba extract and Tremella extract, the concentration of aurantialba extract is 0.015mg/ml to 1.5mg/ml, and the concentration of Tremella extract is 0.015mg/ml to 1.5mg/ml.
One according to the present invention is preferred embodiment, in the combination of aurantialba extract and Tremella extract the weight ratio of aurantialba extract and Tremella extract be 1:5 to 5:1, more preferably weight ratio be 1:2 to 2:1, most preferably weight ratio be 1:1.
The combination of the aurantialba extract obtained prepared according to the methods of the invention and Tremella extract can be directly used for skin moisture-keeping, it is also possible to joins in cosmetics as functional additive and uses.Therefore, according to another object of the present invention, the present invention provides a kind of cosmetic composition, and described compositions contains aurantialba extract and the combination of Tremella extract and the acceptable adjuvant of cosmetic field.
The acceptable adjuvant of described cosmetic field can be selected from: solvent, solubilizing agent, preservative, antioxidant, pH adjusting agent, penetrating agent, liposome, wetting agent, thickening agent, chelating agen, skinfeel regulator, surfactant, emulsifying agent, propelling/propellant, essence, pigment, and other functional additives.
One according to the present invention preferred embodiment, and described compositions can be fancy soap, cleansing milk, bath gel, toner/smoothing toner, skin protection curry, facial treatment milk, protective skin cream, essence, eye cream, facial film, aerosol or Sprayable.These forms can be prepared by method well known to those skilled in the art.
One according to the present invention preferred embodiment, and the combination of described aurantialba extract and Tremella extract accounts for the 0.001-100% of described composition total weight.In one preferred embodiment, the combination of described aurantialba extract and Tremella extract accounts for the 0.01-50% of described composition total weight, more preferably 0.5-20%, most preferably 0.1-5%.
The combination of aurantialba extract of the present invention and Tremella extract can be extracted by method well known to those skilled in the art and be obtained, and such as, depletion ear and Tremella are appropriate, soak with appropriate vehicle, extract with suitable extracting method, are filtrated to get supernatant liquid.
One according to the present invention preferred embodiment, and appropriate vehicle is mainly water (including distilled water, deionized water etc.) or organic solvent (preferably alcohols and esters solvent)；Suitable extraction and purification process selected from following one or more: extract, decoct, reflux, supercritical, precipitate with ethanol, extraction, membrance separation and column chromatography.
The combination of aurantialba extract and Tremella extract has moisture-keeping efficacy, it is possible to give the good moisture-keeping function of skin keratinocytes, helps skin to keep moisture.After adding in cosmetics, there is the effect of moisturizing skin Caring, make skin brilliance moisten.
Accompanying drawing explanation
Fig. 1 shows combination comparison of moistening effect in different time sections of 1.5mg/ml Tremella extract, 1.5mg/ml aurantialba extract, 0.75mg/ml aurantialba extract+0.75mg/ml Tremella extract.
Detailed description of the invention
Unless otherwise defined, all technology used herein and scientific terminology have the identical meanings that one skilled in the art of the present invention are commonly understood by.Although can be used for implementing or testing the present invention with similar or equivalent any method described herein and material, but described herein be preferred method and material.For the purpose of the present invention, following term is defined below.
Terms used herein " about " refers to compared with the quantity with reference product, level, numerical value, dimension, size or consumption, and difference may be up to quantity, level, numerical value, dimension, size or the consumption of 30%, 20% or 10%.
In full piece specification and claims, Unless Otherwise Requested, following word " comprises " and its variant " contains " and " including " is understood to mean that and includes described entirety or step, or one group of overall or step, but be not excluded for other overall or step any, or other group overall or step.
According to the present invention, term " aurantialba extract " refers to the extract containing effective ingredient extracted from Tremella aurantialba Bandoni et Zang by any appropriate ways.Term " Tremella extract " refers to the extract containing effective ingredient extracted from Tremella by any appropriate ways.
According to the present invention, term " cosmetics " refers to smear, spray or other similar approach, intersperse among any position of human body surface, such as skin, hair, refer to toenail, lips and teeth etc., to reach to clean, maintain, improve looks, modify and change outward appearance, or correction human scent, the chemical industrial product for the purpose of maintaining a good state or fine chemical product.According in the preferred embodiment of the present invention, described cosmetics include: moisture-keeping cosmetics, have the anti-inflammatory cosmetics of moisture-keeping efficacy, and have defying age or the skin-lightening cosmetic of moisture-keeping efficacy.
Present invention also offers a kind of cosmetic composition, described compositions contains aurantialba extract and the combination of Tremella extract and the acceptable adjuvant of cosmetic field.Described " the acceptable adjuvant of cosmetic field " can be selected from: solvent, solubilizing agent, preservative, antioxidant, pH adjusting agent, penetrating agent, liposome, wetting agent, thickening agent, chelating agen, skinfeel regulator, surfactant, emulsifying agent, propelling/propellant, essence, pigment, and other functional additives.
In a preferred embodiment in accordance with the present invention, described cosmetic composition can be the forms such as fancy soap, cleansing milk, bath gel, toner/smoothing toner, skin protection curry, facial treatment milk, protective skin cream, essence, eye cream, facial film, aerosol or spraying.These forms of cosmetic composition can be prepared by method well known to those skilled in the art.
Present inventors discovered unexpectedly that: the combination of aurantialba extract and Tremella extract has moisture-keeping efficacy, can be directly used for skin moisture-keeping, it is possible to join in cosmetic composition as functional additive and use.The aurantialba extract prepared according to the inventive method and the combination of Tremella extract, and comprise the cosmetic composition of the combination of aurantialba extract and Tremella extract, skin can be helped to resist in dry environments and to be dried damage, moisturizing skin Caring, make skin brilliance moisten.
Tremella aurantialba Bandoni et Zang and Tremella are all the edible fungi of Tremellales Tremellaceae Tremella.Tremella aurantialba Bandoni et Zang is difficult due to domesticating and cultivating, and yield is few, the most precious, and price is also relatively expensive.Tremella is a kind of common edible fungi, and containing the mucopolysaccharide body of the compositions such as abundant glucose, trehalose, polyacid pentose and mannitol, structure is similar with generally acknowledged moisturizing raw material hyaluronic acid, and moisturizing power is strong, is natural high-quality moisturizing ingredient.Aurantialba extract and Tremella extract are used as cosmetics moisturizing material combination, both can promote moisture-keeping efficacy, the cost that aurantialba extract is used alone, more Applied economy can be reduced again.
During use, in the combination of aurantialba extract and Tremella extract, the concentration of aurantialba extract and Tremella extract can be 0.01mg/ml to 20mg/ml respectively.Such as, during use, in the combination of aurantialba extract and Tremella extract, the concentration of aurantialba extract and Tremella extract can be 0.01mg/ml to 10mg/ml, preferably 0.015mg/ml to 5mg/ml respectively.If added in cosmetics as additive, in terms of the gross weight of cosmetic composition, described cosmetic composition can comprise the aurantialba extract of 0.001-100% and the combination of Tremella extract.In one preferred embodiment of the invention, the combination of described aurantialba extract and Tremella extract accounts for the about 0.5-20% of described composition total weight.
Tremella aurantialba Bandoni et Zang (TremellaaurantialbaBandonietZang), for Mycophyta door fungus, also known as Tremella mesenterica Retz ex Fr., cyclopentadienyl Ruo Seerbu (Tibetan language), golden yellow Tremella, yellow ear, brain ear.Tremella aurantialba Bandoni et Zang is a kind of Tibetan medicine, cures mainly Pulmonary Diseases.Tremella aurantialba Bandoni et Zang contains golden fungus polysaccharides, various aminoacid, vitamin B group etc..Modern medicine research shows: Tremella aurantialba Bandoni et Zang is improved function of nervous system, regulation body cell physiologically active, blood fat reducing, the liver protecting, raising hemopoietic function, improves the effects such as immunity.Tremella aurantialba Bandoni et Zang is a kind of edible fungi more precious than Tremella, and because yielding poorly, expensive, application person is less, knows that its person is the most less.
Tremella, is again Tremella, is the famous food and medicament dual-purpose fungus of China, is the excellent tonic product of life lengthening, is " strengthening the body resistance " medicine that the traditional Chinese medical science is traditional.It is documented: Tremella have the kidney invigorating, lung moistening, promote the production of body fluid, many effects such as cough-relieving.Written by Zhang Renan described in " book on Chinese herbal medicine poem solution property of medicine note ": this thing has the profit of Radix Ophiopogonis to tremble with fear without it, have Rhizoma Polygonati Odorati sweet and greasy without it, it is the top grade of lung moistening nourishing YIN, can match in excellence or beauty with Radix Ginseng, Cornu Cervi Pantotrichum, Nidus collocaliae, have preventing and treating cough due to lung-heat, the dryness of the lung anxious to cough, chronic cough itching of the throat, cough band blood, chronic cough network are hindered hypochondriac pain, pain in the lung and gastritis, constipation, had blood in stool and effect of menoxenia.
The modern study of Tremella aurantialba Bandoni et Zang is concentrated mainly on its edible and medical value.Tremella aurantialba Bandoni et Zang contains trace element such as enriching fatty, protein and phosphorus, sulfur, manganese, ferrum, magnesium, calcium, potassium, is a kind of tonic food.The nourishing the human Body of Tremella aurantialba Bandoni et Zang is worth and is better than the colloid mushroom such as Tremella, Auricularia, is a kind of preferable senior dinner delicacies and health-care good product.Its medicinal function includes: 1. improve organism metabolism function, the growth of suppression tumor cell.2. regulation organism metabolism function, improves body nutriture, improves body blood Lactoferrin and the content of blood plasma.3. body defying age, anti-anoxia ability, blood fat reducing, cholesterol reducing are improved.4. promote liver lipid metabolism, prevent fat from accumulating at liver, improve liver detoxification function.Often edible can illness prevention and fitness, slow down aging effectively.
The modern study of Tremella is then concentrated mainly on its edibility.It is tonic medicine simply, moist and oiliness stagnant, has spleen reinforcing appetizing, QI invigorating bowel relieving, the merit of sleeping stomach invigorating.Tremella is also to plant the diet food rich in dietary fiber, and its dietary fiber can help gastrointestinal peristalsis, reduces fat absorption.
All being not directed to the combination of aurantialba extract and the Tremella extract application in cosmetics in document, the combination of more not mentioned aurantialba extract and Tremella extract has moistening effect.Therefore, present invention firstly provides Tremella aurantialba Bandoni et Zang and there is moisture-keeping efficacy, can add as functional additive in the cosmetic composition of moisturizing, help skin to resist in dry environments and be dried damage, moisturizing skin Caring.
The combination of aurantialba extract of the present invention and Tremella extract can be extracted by method well known to those skilled in the art and be obtained, and such as, depletion ear and Tremella are appropriate, soak with appropriate vehicle, extract with suitable extracting method, are filtrated to get supernatant liquid.
One according to the present invention preferred embodiment, and appropriate vehicle is mainly water (including distilled water, deionized water etc.) or organic solvent (preferably alcohols and esters solvent)；Suitable extraction and purification process selected from following one or more: extract, decoct, reflux, supercritical, precipitate with ethanol, extraction, membrance separation and column chromatography.
The present invention is expanded on further below in conjunction with specific embodiment.It should be appreciated, however, that these embodiments are merely to illustrate the present invention and are not meant to limit the scope of the invention.The test method of unreceipted actual conditions in the following example, generally according to normal condition, or according to the condition proposed by manufacturer.Except as otherwise noted, all of percentage ratio and number are by mass.
Embodiment 1
The Tremella aurantialba Bandoni et Zang taking pulverizing is appropriate, is poured in extraction pot, adds 40 times amount (W/V) water, is sufficiently stirred for mixing, and under the conditions of 60 DEG C, insulation extraction 2 hours, filter, discard filtering residue, and filtrate is gained.
The Tremella taking pulverizing is appropriate, is poured in extraction pot, adds 40 times amount (W/V) water, is sufficiently stirred for mixing, and under the conditions of 60 DEG C, insulation extraction 2 hours, filter, discard filtering residue, and filtrate is gained.
Embodiment 2
The Tremella aurantialba Bandoni et Zang taking pulverizing is appropriate, is poured in extraction pot, adds 20 times amount (W/V) water, is sufficiently stirred for mixing, and insulation extraction 2 hours under the conditions of 80 DEG C, discontinuity is stirred, and extracts 2 times；Filtering, discard filtering residue, merging filtrate, filtrate heating is concentrated into appropriate, places cooling.It is slowly added to 95% ethanol while stirring, makes ethanol final concentration of 60～75%, stand overnight.Filtering, take supernatant, add ethyl acetate and extract 3 times, extract flings to solvent, adds ethanol in proper amount and dissolves.
The Tremella taking pulverizing is appropriate, is poured in extraction pot, adds 20 times amount (W/V) water, is sufficiently stirred for mixing, and insulation extraction 2 hours under the conditions of 80 DEG C, discontinuity is stirred, and extracts 2 times；Filtering, discard filtering residue, merging filtrate, filtrate heating is concentrated into appropriate, places cooling.It is slowly added to 95% ethanol while stirring, makes ethanol final concentration of 60～75%, stand overnight.Filtering, take supernatant, add ethyl acetate and extract 3 times, extract flings to solvent, adds ethanol in proper amount and dissolves.
Embodiment 3
The Tremella aurantialba Bandoni et Zang taking pulverizing is appropriate, is poured in extraction pot, adds 20 times amount (W/V) water, is sufficiently stirred for mixing, and insulation extraction 2 hours under the conditions of 80 DEG C, discontinuity is stirred, and extracts 2 times；Filtering, discard filtering residue, merging filtrate, filtrate heating is concentrated into appropriate, places cooling.It is slowly added to 95% ethanol while stirring, makes ethanol final concentration of 60～75%, stand overnight.Filter, take filtering residue and reclaim ethanol at reduced pressure conditions to without alcohol taste, residue addition suitable quantity of water dissolving.
The Tremella taking pulverizing is appropriate, is poured in extraction pot, adds 20 times amount (W/V) water, is sufficiently stirred for mixing, and insulation extraction 2 hours under the conditions of 80 DEG C, discontinuity is stirred, and extracts 2 times；Filtering, discard filtering residue, merging filtrate, filtrate heating is concentrated into appropriate, places cooling.It is slowly added to 95% ethanol while stirring, makes ethanol final concentration of 60～75%, stand overnight.Filter, take filtering residue and reclaim ethanol at reduced pressure conditions to without alcohol taste, residue addition suitable quantity of water dissolving.
Embodiment 4
The Tremella aurantialba Bandoni et Zang taking pulverizing is appropriate, is poured in extraction pot, adds 20 times amount (W/V) water, is sufficiently stirred for mixing, and 1 hour post-heating of merceration, to boiling, keeps micro-boiling 2 hours, extracts 2 times；Filtering, discard filtering residue, merge 2 filtrates, filtrate heating is concentrated into appropriate, is centrifuged and discards sediment after cooling.Supernatant adds deionized water and mixes in right amount, join in the most pretreated D101 macroporous resin column (purchased from Tianjin insecticide factory, preprocessing process: being dipped to ethanol solution for several times with 95% ethanol is clear, post is rushed to without ethanol taste again) with water, first it is eluted to distilled water the most colourless, then with 4 times amount 50% ethanol elutions, collects ethanol elution, eluent concentrating under reduced pressure reclaims ethanol to without alcohol taste, residual liquid addition suitable quantity of water dissolving (also can add the appropriate hydrotropy of propylene glycol).
The Tremella taking pulverizing is appropriate, is poured in extraction pot, adds 20 times amount (W/V) water, is sufficiently stirred for mixing, and 1 hour post-heating of merceration, to boiling, keeps micro-boiling 2 hours, extracts 2 times；Filtering, discard filtering residue, merge 2 filtrates, filtrate heating is concentrated into appropriate, is centrifuged and discards sediment after cooling.Supernatant adds deionized water and mixes in right amount, join in the most pretreated D101 macroporous resin column (purchased from Tianjin insecticide factory, preprocessing process: being dipped to ethanol solution for several times with 95% ethanol is clear, post is rushed to without ethanol taste again) with water, first it is eluted to distilled water the most colourless, then with 4 times amount 50% ethanol elutions, collects ethanol elution, eluent concentrating under reduced pressure reclaims ethanol to without alcohol taste, residual liquid addition suitable quantity of water dissolving (also can add the appropriate hydrotropy of propylene glycol).
Embodiment 5
The Tremella aurantialba Bandoni et Zang taking pulverizing is appropriate, is poured in extraction pot, adds 30 times amount (W/V) water, is sufficiently stirred for mixing, and 1 hour post-heating of merceration, to boiling, keeps micro-boiling 2 hours, extracts 1～2 time；Filtering, discard filtering residue, merge 2 filtrates, after cotton balls coarse filtration, upper membrane separation device (Xiamen Filter and Membrane Technology Co., Ltd., model: RNF-0460), regulates suitable pressure and flow, isolates molecular weight effective part group between 2000～200000.
The Tremella taking pulverizing is appropriate, is poured in extraction pot, adds 30 times amount (W/V) water, is sufficiently stirred for mixing, and 1 hour post-heating of merceration, to boiling, keeps micro-boiling 2 hours, extracts 1～2 time；Filtering, discard filtering residue, merge 2 filtrates, after cotton balls coarse filtration, upper membrane separation device (Xiamen Filter and Membrane Technology Co., Ltd., model: RNF-0460), regulates suitable pressure and flow, isolates molecular weight effective part group between 2000～200000.
Embodiment 6: resist the moisture loss experiment under dry environment
Aurantialba extract sample solution used in the present embodiment is the aurantialba extract for preparing of embodiment 1 and Tremella extract.
6.1. experimental principle
Water is to be done eternal random motion by the molecular molecule of moisture.When in a dry environment, in hydrone easy movement to air, now moisture the most slowly scatters and disappears.
6.2. experimental technique
For simulated skin state, select the microscope slide of 25.4 × 76.2mm, stick 3M adhesive tape.Aurantialba extract is configured to certain density aqueous solution, weighs the sample of about 200mg, by its uniform application on microscope slide, put into the instrument of constant temperature and humidity.This experiment is carried out under room temperature (25 DEG C), uses saturated ammonium sulfate solution to control the constant humidity environment of 80%.Weighing after certain time (30,60,90,120,150 minutes), calculate the percentage of water loss of sample, compare moisturizing rate by the size of percentage of water loss, percentage of water loss the least expression moistening effect is the best.
Percentage of water loss (%)=(M2-M3)/(M2-M1) × 100%
M1 microscope slide weight (g)
M2 places front gross weight (g) after smearing
M3 smear after place after gross weight (g)
Tremella aurantialba Bandoni et Zang and Tremella are all the edible fungi of Tremellales Tremellaceae Tremella.Tremella aurantialba Bandoni et Zang is difficult due to domesticating and cultivating, and yield is few, the most precious, and price is also relatively expensive.Tremella is a kind of common edible fungi, and containing the mucopolysaccharide body of the compositions such as abundant glucose, trehalose, polyacid pentose and mannitol, structure is similar with generally acknowledged moisturizing raw material hyaluronic acid, and moisturizing power is strong, is natural high-quality moisturizing ingredient.Aurantialba extract and Tremella extract are used as cosmetics moisturizing material combination, both can promote moisture-keeping efficacy, the cost that aurantialba extract is used alone, more Applied economy can be reduced again.
Experiment confirms, the combination of aurantialba extract and Tremella extract has good moisture-keeping efficacy, be applied in combination as Tremella aurantialba Bandoni et Zang and Tremella extract are each halved consumption, then the moistening effect that combination is reached is even more significantly than the moistening effect being used alone aurantialba extract or Tremella extract.
Claims (10)
1. the aurantialba extract of non-treatment purpose and the combination of Tremella extract application in helping skin to resist the cosmetics being dried damage, wherein, described aurantialba extract and Tremella extract are adopted and are used water as Extraction solvent.
Apply the most as claimed in claim 1, it is characterised in that described cosmetics are moisture-keeping cosmetics.
Apply the most as claimed in claim 2, it is characterised in that described moisture-keeping cosmetics is selected from: there are the anti-inflammatory cosmetics of moisture-keeping efficacy, there is the anti-aging cosmetics of moisture-keeping efficacy or there is the skin-lightening cosmetic of moisture-keeping efficacy.
Apply the most as claimed in claim 1, it is characterised in that described cosmetics are following forms: fancy soap, cleansing milk, bath gel, toner/smoothing toner, skin protection curry, facial treatment milk, protective skin cream, essence, eye cream, facial film, aerosol or Sprayable.
Apply the most as claimed in claim 1, it is characterised in that described cosmetics also comprise the acceptable adjuvant of cosmetic field.
Apply the most as claimed in claim 5, it is characterized in that, the acceptable adjuvant of described cosmetic field is selected from: solvent, solubilizing agent, preservative, antioxidant, pH adjusting agent, penetrating agent, liposome, wetting agent, thickening agent, chelating agen, skinfeel regulator, surfactant, emulsifying agent, propelling/propellant, essence, pigment.
Applying the most as claimed in claim 1, it is characterised in that during use, in the combination of described aurantialba extract and Tremella extract, the concentration of aurantialba extract is 0.01mg/ml to 20mg/ml, and the concentration of Tremella extract is 0.01mg/ml to 20mg/ml.
Applying the most as claimed in claim 7, it is characterised in that during use, in the combination of described aurantialba extract and Tremella extract, the concentration of aurantialba extract is 0.01mg/ml to 10mg/ml, and the concentration of Tremella extract is 0.01mg/ml to 10mg/ml.
Applying the most as claimed in claim 7, it is characterised in that during use, in the combination of described aurantialba extract and Tremella extract, the concentration of aurantialba extract is 0.015mg/ml to 5mg/ml, and the concentration of Tremella extract is 0.015mg/ml to 5mg/ml.
Apply the most as claimed in claim 1, it is characterised in that in the combination of described aurantialba extract and Tremella extract, the weight ratio of aurantialba extract and Tremella extract is 1:1.
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| CN201210269076.5A CN103565722B (en) | 2012-07-30 | 2012-07-30 | The combination of aurantialba extract and Tremella extract application in cosmetics |
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| CN201210269076.5A CN103565722B (en) | 2012-07-30 | 2012-07-30 | The combination of aurantialba extract and Tremella extract application in cosmetics |
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| CN103565722A CN103565722A (en) | 2014-02-12 |
| CN103565722B true CN103565722B (en) | 2016-08-03 |
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| CN105193661A (en) * | 2015-10-11 | 2015-12-30 | 庄健峰 | Moisturizing and anti-inflammatory essence cream and preparation method thereof |
| CN105534812A (en) * | 2016-01-19 | 2016-05-04 | 中山百鸥医药科技有限公司 | Essence and preparation method thereof |
| CN107661262A (en) * | 2017-10-28 | 2018-02-06 | 安徽孔氏奇医药科技有限公司 | One kind is compacted radioresistance eye cream and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1451312A (en) * | 2002-04-18 | 2003-10-29 | 中华全国供销合作社昆明食用菌研究所 | Pure Jin'er fungus product and producing method thereof |
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| CN1451312A (en) * | 2002-04-18 | 2003-10-29 | 中华全国供销合作社昆明食用菌研究所 | Pure Jin'er fungus product and producing method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 暴增海等.我国金耳资源及其开发利用研究.《自然资源》.1996,(第4期), * |
| 陈岗.银耳多糖的功能特性及其应用.《中国食品添加剂》.2011,(第4期), * |
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