CN106165802A - A kind of suppressing the hyperactive liver lung heat clearing peaceful network hemostasis beverage and preparation processing method - Google Patents
A kind of suppressing the hyperactive liver lung heat clearing peaceful network hemostasis beverage and preparation processing method Download PDFInfo
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/02—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation containing fruit or vegetable juices
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The invention discloses a kind of suppressing the hyperactive liver lung heat clearing peaceful network hemostasis beverage of the present invention, be made up of the raw material of following weight portion: new fresh Herba Dendrobii 15 parts, Fructus Vitis viniferae 15 parts, 5 15 parts of Folium Mori, Cortex Lycii 5 15 parts, Radix Glycyrrhizae 5 15 parts, 8 15 parts of the Radix Rehmanniae, Radix Sanguisorbae 5 10 parts, Folium Eriobotryae 5 15 parts, Radix Scutellariae 5 12 parts, 5 15 parts of Colla Corii Asini, Nodus Nelumbinis Rhizomatis 5 16 parts, south Plantula Papaveris 15 25 parts, Radix Peucedani 5 15 parts, the Rhizoma Pinelliae 5 15 parts, Mel, water are appropriate.The invention have the advantage that inventive formulation has the function such as suppressing the hyperactive liver lung heat clearing, peaceful network hemostasis, carries and drinks conveniently, improves self and increases the wriggling of the intestines and stomach, and cure the disease strengthens the beverage of body immunity simultaneously, and the shelf-life is up to 12 years.
Description
Technical field
The present invention relates to a kind of suppressing the hyperactive liver lung heat clearing peaceful network hemostasis beverage, in particular, relate to a kind of peaceful network of suppressing the hyperactive liver lung heat clearing
Hemostasis drink formula and preparation method thereof technical field.
Background technology
The most traditional beverage, only focuses on mouthfeel, is of low nutritive value, do not have suppressing the hyperactive liver lung heat clearing, peaceful network hemostasis preventing and treating lung have
Scorching, overabundant liver-fire, lung network of burning, bronchus are spat blood, are improved body immunity, defying age, eliminating toxin and beautifying the skin, nourishing taste, fall
Three-hypers, prevent and treat diabetes and anti-cancer, the function of the aspect such as anticancer, it is impossible to release the sufferings of client, and during traditional herbal tea passes through
Medicine boils, and flavour of a drug weight mouthfeel is poor, it is impossible to preserve for a long time.The most not yet occur a kind of in good taste, improve self and increase intestinal
The wriggling of stomach, cures the disease and strengthens the beverage of body immunity simultaneously.
Summary of the invention
The present invention is directed to the deficiency of existing product, and provide a kind of fresh juice beverage to regulate the effect of human physiological functions,
This beverage have be easily absorbed by the human body, medicinal function is notable, delicious flavour, good mouthfeel, improve self and increase the wriggling of the intestines and stomach,
Cure the disease and strengthen a kind of suppressing the hyperactive liver lung heat clearing peaceful network hemostasis beverage of the advantages such as body immunity simultaneously.
A kind of suppressing the hyperactive liver lung heat clearing peaceful network hemostasis beverage of the present invention, is made up of the raw material of following weight portion: new fresh Herba Dendrobii 10-20
Part, Fructus Vitis viniferae 10-20 part, Folium Mori 5-15 part, Cortex Lycii 5-15 part, Radix Glycyrrhizae 5-15 part, Radix Rehmanniae 8-15 part, Radix Sanguisorbae 5-10 part, Pi
Rake leaf 5-15 part, Radix Scutellariae 5-12 part, Colla Corii Asini 5-15 part, Nodus Nelumbinis Rhizomatis 5-16 part, Radix Peucedani 5-15 part, Rhizoma Pinelliae 5-15 part, Air Bladder pseudosciaenae seu Acipenser 5-10 part,
Mel, water are appropriate；
The preparation processing method of described a kind of suppressing the hyperactive liver lung heat clearing peaceful network hemostasis beverage, comprises the following steps；
A, fresh for Herba Dendrobii bar is put into service sink, remove surface clay stain, the fresh bar of screening high-quality Herba Dendrobii, dry standby；
B, fresh for the Herba Dendrobii cleaned up bar is put into microwave oven, keep temperature 50-60 DEG C, carry out heating 10 minutes, then take
Go out to put into rotating centrifugal juice extractor, carry out three times and squeeze the juice, add the alcohol content of Herba Dendrobii fresh bar weight 0.1-0.5 times for the first time
The Chinese liquor of 52-60 DEG C, time 10-15min, the rotating speed of juice extractor is 20～30r/s；After standing 10 minutes, add the fresh bar of Herba Dendrobii
The distilled water of weight 2-3 times, for the second time juice extractor time 10-15min, juice extractor rotating speed is 80～100r/s, stands 10min；
After carry out third time squeeze the juice, add Herba Dendrobii fresh bar weight 3-5 times distilled water, time 20-30min, juice extractor rotating speed be 100～
150r/s, separates fresh for Herba Dendrobii bar juice with fiber filter, makes the fiber separation rate of the fresh bar of Herba Dendrobii reach more than 95%, cell damage
Rate reaches more than 80%, obtains new fresh Herba Dendrobii juice and Herba Dendrobii fresh bar fiber；The warm water that new fresh grape is put into 50-60 DEG C again cleans dry
After Jing, Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae are separated stand-by；
C, Herba Dendrobii fresh bar juice is put into and is put in pressure pan with Fructus Vitis viniferae meat, keeps pressure 0.5MP, temperature to keep 100-150 in tank
Degree, carries out infusion 10 minutes, obtains Matrix Solution I standby；
D, fresh for the Herba Dendrobii of separation bar fiber and Pericarpium Vitis viniferae are put into unglazed hermetically sealed can, in hermetically sealed can, add that to be equivalent to Herba Dendrobii fresh
Bar fiber and the Mel of Pericarpium Vitis viniferae gross weight 20-30% and the distilled water of 5-10 times of weight, stirring is smashed to 100 mesh, at 30-35
Seal at a temperature of DEG C and preserve 24h, sterilizing, filter, put into unglazed hermetically sealed can, obtain Matrix Solution standby；After extracting Matrix Solution
It is the cellulase of 0.5-0.7% that Pericarpium Vitis viniferae and Herba Dendrobii fresh bar fiber add mass volume ratio, adds the water of the mass ratio of 1:10,
Keep 35 DEG C, water soluble dietary fiber can be extracted further after 24h enzymolysis, water soluble dietary fiber is added Matrix Solution
Obtain Matrix Solution II；
E, take Folium Mori, Cortex Lycii, Radix Glycyrrhizae, the Radix Rehmanniae, Radix Sanguisorbae, Folium Eriobotryae, Radix Scutellariae, Colla Corii Asini, Nodus Nelumbinis Rhizomatis, Radix Peucedani, the Rhizoma Pinelliae, Air Bladder pseudosciaenae seu Acipenser, mixed
Close after uniformly adding 30-60 DEG C of warm water soaking 10 minutes, put into reach in freezer ,-10～-20 DEG C freezing 10-20 minute, formed cold
Freezing medicine block, freezing medicine block boiling extracted 3 times, add 1-2 times amount water for the first time, temperature keeps 100-120 DEG C, carries out infusion
10-20 minute；Second time adds 4-6 times amount water, and temperature keeps 80-100 DEG C, carries out infusion 10 minutes；Third time adds 6-10 times amount
Water, temperature keeps 120-150 DEG C, carries out infusion 30 minutes, filters, is concentrated into the 1/2 of original volume, obtains Matrix Solution III standby
With；
F, take Matrix Solution I through instantaneous high-temperature 110-130 DEG C, 1-2 minute, put into material-compound tank；Take Matrix Solution II through mesh
Number be 100 mesh fine filter filter after put into material-compound tank；Take Matrix Solution III again to put into after the fine filter filter that mesh number is 60 mesh
In material-compound tank；
G, by Semen Vitis viniferae through vacuum outgas, then use CO2 supercritical fluid extraction, the condition of CO2 supercritical fluid extraction is:
Extracting pressure 45MPa, extraction temperature 35-45 DEG C, extraction time 30min, isolated Oleum Vitis viniferae；
H, three kinds of Matrix Solutions are stirring evenly and then adding into Oleum Vitis viniferae at material-compound tank, seal through bottle capper and load in vial,
Packaged vial puts into temperature 100～120 DEG C, 1.5MP, sterilization in 15～21 minutes steam ovens, packaging, vanning.
Further: step B) in, after new fresh grape cleans up, put into reach in freezer, at the freezing 5-10 in-10～-20 DEG C
Minute, make Fructus Vitis viniferae freeze, after taking out nature defrosting, then carry out Fructus Vitis viniferae meat and Pericarpium Vitis viniferae detached job.
Further: step H) described in material-compound tank endobasal-body solution I, Matrix Solution II, Matrix Solution III, Oleum Vitis viniferae
Weight proportion be 10:0.2～0.8:5～10:0.5.
Folium Mori, dispelling wind and heat pathogens, lung heat clearing, improving eyesight.Main anemopyretic cold;Pathogenic wind-warm from the beginning of, fever and headache, perspiration and aversion to wind, breast of coughing
Bitterly;Or dryness of the lung dry cough without phlegm.
Folium Eriobotryae, has clearing away lung-heat to relieve cough, regulating the stomach and sending down the abnormal ascending QI, the effect quenched the thirst.
Radix Glycyrrhizae, and middle emergency, lung moistening, removing toxic substances, coordinating the actions of various ingredients in a prescription.
Radix Scutellariae, has heat clearing and damp drying, removing heat from blood, detoxicating functions.
Cortex Lycii, removing heat from blood is except steaming, lung heat clearing pathogenic fire reducing.
The Radix Rehmanniae, sweet in the mouth, cold.Hemopoietic removing heat from blood, cures mainly folding and falls, exhausted muscle, damaging the spleen and stomach, by arthralgia due to stagnation of blood, fills out bone marrow, long muscle.
Radix Sanguisorbae, cooling blood for hemostasis, heat-clearing and toxic substances removing, sore of subsiding a swelling.
Colla Corii Asini, YIN nourishing of enriching blood, moisturize, hemostasis.For blood deficiency and yellow complexion, dizziness cardiopalmus, dysphoria and insomnia, xeropulmonary cough.
Nodus Nelumbinis Rhizomatis, returns liver, lung, stomach warp, astringing to arrest bleeding, blood stasis dispelling.
Radix Peucedani, dissipates wind heat clearing away, lowering the adverse-rising QI to resolve phlegm.For affection due to external wind and heat, lung-heat phlegm stagnancy, cough with asthma abundant expectoration, expectorant Huang food sticky, inverse
Less, chest and diaphragm is full vexed.
The Rhizoma Pinelliae, drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.Controlling damp-phlegm cold drink, vomiting, regurgitation, cough with asthma abundant expectoration, chest and diaphragm is swollen
Full, syncope due to accumulation of phlegm is had a headache, dizzy sleeplessness.
The natural tradition medicinal and edible Chinese medicine above with multiple health care is share, there is suppressing the hyperactive liver lung heat clearing, Ning Luozhi
Effect of blood, has treatment lung and has scorching, overabundant liver-fire, lung network of burning, bronchus spitting of blood, dyspepsia, the merit of fatigue.Pass through
Great many of experiments screens the proportioning of each component, scientific and reasonable；And whole preparation technology is rationally and extract drugs rate efficiency is high, can be very
Retain well the effective ingredient in raw material, do not bring any impurity, and sweet mouthfeel into, have no side effect.
The invention has the beneficial effects as follows:
1, the formula of the present invention, has promoting the production of body fluid to quench thirst, gastric acid secretion, helps digest, and health body-building has calm nerves and declines
Weak, lessen fatigue, containing various trace elements such as calcium, ferrum, zinc, selenium, sodium etc., raising body immunity, defying age, toxin expelling are supported
Face, nourish taste, three-hypers drops, to prevent and treat diabetes and anti-cancer, the aspect such as anticancer the most powerful, regulates human physiological functions.
2, the present invention is rich in anthocyanidin, it is possible to protection human body is from the damage of free radical, it is possible to strengthens blood vessel elasticity, relax
Blood vessel, increases systemic blood circulation, has certain blood pressure reduction effect；Immune system ability can be strengthened, there is strong anti-oxidation, resist
Suddenly change, alleviate the function such as hepatosis, protection cardiovascular；
3, the medium-height grass such as Folium Mori, Cortex Lycii, Radix Glycyrrhizae, the Radix Rehmanniae, Radix Sanguisorbae, Folium Eriobotryae, Radix Scutellariae, Colla Corii Asini, Nodus Nelumbinis Rhizomatis, Radix Peucedani, the Rhizoma Pinelliae are added
Medical instrument has the function such as suppressing the hyperactive liver lung heat clearing, peaceful network hemostasis.
4, the products taste that the production technology of the present invention and preparation method draw is sour-sweet tasty and refreshing, rich in dendrobium polysaccharide, has
The highest health care and medical value, long-term drink can with YIN nourishing skin care, change skin colour, defying age, life lengthening, and
Carrying and drink conveniently, improve self and increase the wriggling of the intestines and stomach, cure the disease and strengthen the beverage of body immunity simultaneously, the shelf-life is up to 1-
2 years.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further described, in order to those skilled in the art knows more about
The present invention, but and it is not so limited the present invention.
Embodiment 1
A kind of suppressing the hyperactive liver lung heat clearing peaceful network hemostasis beverage, is made up of the raw material of following weight portion: new fresh Herba Dendrobii 15 parts, Fructus Vitis viniferae 15 parts, Mulberry
8 parts of leaf, Cortex Lycii 8 parts, Radix Glycyrrhizae 8 parts, 8 parts of the Radix Rehmanniae, Radix Sanguisorbae 8 parts, Folium Eriobotryae 8 parts, Radix Scutellariae 8 parts, 8 parts of Colla Corii Asini, Nodus Nelumbinis Rhizomatis 8 parts,
South Plantula Papaveris 20 parts, Radix Peucedani 8 parts, the Rhizoma Pinelliae 8 parts, Air Bladder pseudosciaenae seu Acipenser 5-10 part, Mel, water are appropriate；
The preparation processing method of a kind of suppressing the hyperactive liver lung heat clearing peaceful network hemostasis beverage, described preparation method comprises the following steps；
A, fresh for Herba Dendrobii bar is put into service sink, remove surface clay stain, the fresh bar of screening high-quality Herba Dendrobii, dry standby；
Fresh for the Herba Dendrobii cleaned up bar is put into microwave oven by B, keeps temperature 50-60 DEG C, carries out heating 10 minutes, further take out
Put into rotating centrifugal juice extractor, carry out three times and squeeze the juice, add the alcohol content 52 of Herba Dendrobii fresh bar weight 0.1-0.5 times for the first time
DEG C Chinese liquor, time 15min, the rotating speed of juice extractor is 30r/s；After standing 10 minutes, add the steaming of Herba Dendrobii fresh bar weight 2.5 times
Distilled water, for the second time juice extractor time 15min, juice extractor rotating speed is 80r/s, stands 10min；After carry out third time squeeze the juice, add
The distilled water of Herba Dendrobii fresh bar weight 3-5 times, time 30min, juice extractor rotating speed is 150r/s, by fresh for Herba Dendrobii bar juice and fiber mistake
Filter separate, make the fiber separation rate of the fresh bar of Herba Dendrobii reach more than 95%, broken cell rate reaches more than 80%, obtain new fresh Herba Dendrobii juice and
Herba Dendrobii fresh bar fiber；Again new fresh grape is put into after the warm water of 55 DEG C cleans up, Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae are separated
Stand-by；After new fresh grape cleans up, put into reach in freezer ,-10 ~-20 DEG C of freezings 10 minutes, make Fructus Vitis viniferae freeze, take out certainly
After so thawing, then carry out Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae detached job.
C, Herba Dendrobii fresh bar juice is put into and is put in pressure pan with Fructus Vitis viniferae meat, keeps pressure 0.5MP, temperature to keep 120 in tank
Degree, carries out infusion 10 minutes, obtains Matrix Solution I standby；
D, fresh for the Herba Dendrobii of separation bar fiber and Pericarpium Vitis viniferae are put into unglazed hermetically sealed can, in hermetically sealed can, add that to be equivalent to Herba Dendrobii fresh
Bar fiber and the Mel of Pericarpium Vitis viniferae gross weight 20-30% and the distilled water of 6 times of weight, stirring is smashed to 100 mesh, 30-35 DEG C of temperature
Degree lower seal preserves 24h, sterilizing, filters, puts into unglazed hermetically sealed can, obtain Matrix Solution standby；Extract the Fructus Vitis viniferae after Matrix Solution
It is the cellulase of 0.5-0.7% that skin and Herba Dendrobii fresh bar fiber add mass volume ratio, adds the water of the mass ratio of 1:10, keeps
35 DEG C, water soluble dietary fiber can be extracted after 24h enzymolysis further, water soluble dietary fiber is added Matrix Solution and obtains
Matrix Solution II；；Rich in anthocyanidin in Pericarpium Vitis viniferae, it is possible to protection human body is from the damage of free radical, it is possible to enhancing blood vessel elasticity,
Lax blood vessel, increases systemic blood circulation, has certain blood pressure reduction effect；Immune system ability can be strengthened, there is strong antioxygen
Change, mutation, alleviate hepatosis, protection function, Pericarpium Vitis viniferae and the Herba Dendrobii fresh bar fiber such as cardiovascular together with stir smash through
Anthocyanidin mentioned by hydromel, can protect the quality of anthocyanidin while farthest extracting anthocyanidin.By water solublity meals
Food fiber adds Matrix Solution and obtains Matrix Solution II, can increase effect of the wriggling of the intestines and stomach, it is ensured that metabolic waste is normally discharged
External；Adsorb various metabolic waste, be allowed to normally excrete, improve the comprehensive utilization value of Herba Dendrobii.
E, take Folium Mori, Cortex Lycii, Radix Glycyrrhizae, the Radix Rehmanniae, Radix Sanguisorbae, Folium Eriobotryae, Radix Scutellariae, Colla Corii Asini, Nodus Nelumbinis Rhizomatis, south Plantula Papaveris, Radix Peucedani, half
After summer, Air Bladder pseudosciaenae seu Acipenser mix homogeneously add 30-60 DEG C of warm water soaking 10 minutes, put into reach in freezer ,-10～-20 DEG C of freezings 20 minutes,
Forming freezing medicine block, freezing medicine block boiling extracted 3 times, add 1-2 times amount water for the first time, temperature keeps 100-120 DEG C, enters
Row infusion 10-20 minute；Second time adds 6 times amount water, and temperature keeps 80-100 DEG C, carries out infusion 10 minutes；Third time adds 6-10
Times amount water, temperature keeps 120-150 DEG C, carries out infusion 30 minutes, filters, is concentrated into the 1/2 of original volume, obtains Matrix Solution
III is standby；Chinese medicine foamed good after after freezing, cell wall crystallization ruptures, and forms freezing medicine block, then in high temperature infusion makes
The composition of medicine farthest extracts.
F, take Matrix Solution I through instantaneous high-temperature 120 DEG C, 1-2 minute, put into material-compound tank；Take Matrix Solution II through mesh
Number be 100 mesh fine filter filter after put into material-compound tank；Take Matrix Solution III again to put into after the fine filter filter that mesh number is 60 mesh
In material-compound tank；
G, by Semen Vitis viniferae through vacuum outgas, then use CO2 supercritical fluid extraction, the condition of CO2 supercritical fluid extraction is:
Extracting pressure 45MPa, extraction temperature 35-45 DEG C, extraction time 30min, isolated Oleum Vitis viniferae；Supercritical extraction can be
Extract under room temperature 37 DEG C and CO2 gas blanket, effectively prevent oxidation and the loss of heat-sensitive substance.Therefore,
The effective ingredient of medicinal plants is remain in extract, and can be high boiling point, low volatility, the easy material being pyrolyzed the lowest
Extract under its boiling temperature；
H, three kinds of Matrix Solutions are stirring evenly and then adding into Oleum Vitis viniferae at material-compound tank, and described material-compound tank endobasal-body solution I, matrix are molten
Liquid II, Matrix Solution III, the weight proportion of Oleum Vitis viniferae are 10:0.5:6:0.5., seal through bottle capper and load vial
In, packaged vial puts into temperature 100～120 DEG C, 1.5MP, sterilization in 15～21 minutes steam ovens, packaging, dress
Case, carries and drinks conveniently, and the shelf-life is up to 1-2.
Embodiment 2
A kind of suppressing the hyperactive liver lung heat clearing peaceful network hemostasis beverage, is made up of the raw material of following weight portion: be made up of the raw material of following weight portion: by
The raw material of following weight portion is made: new fresh Herba Dendrobii 10 parts, Fructus Vitis viniferae 10 parts, 5 parts of Folium Mori, Cortex Lycii 5 parts, Radix Glycyrrhizae 5 parts, the Radix Rehmanniae 8
Part, Radix Sanguisorbae 5 parts, Folium Eriobotryae 5 parts, Radix Scutellariae 5 parts, 5 parts of Colla Corii Asini, Nodus Nelumbinis Rhizomatis 5 parts, south Plantula Papaveris 15 parts, Radix Peucedani 5 parts, the Rhizoma Pinelliae 5 parts, Air Bladder pseudosciaenae seu Acipenser 5
Part, Mel, water are appropriate；Processing method is with embodiment 1.
Embodiment 3
A kind of suppressing the hyperactive liver lung heat clearing peaceful network hemostasis beverage, is made up of the raw material of following weight portion: be made up of the raw material of following weight portion: new
Fresh Herba Dendrobii 20 parts, Fructus Vitis viniferae 20 parts, 15 parts of Folium Mori, Cortex Lycii 15 parts, Radix Glycyrrhizae 15 parts, 15 parts of the Radix Rehmanniae, Radix Sanguisorbae 10 parts, Folium Eriobotryae 15
Part, Radix Scutellariae 12 parts, 15 parts of Colla Corii Asini, Nodus Nelumbinis Rhizomatis 16 parts, south Plantula Papaveris 25 parts, Radix Peucedani 15 parts, the Rhizoma Pinelliae 15 parts, 10 parts of Air Bladder pseudosciaenae seu Acipenser, Mel, water are fitted
Amount；Processing method is with embodiment 1.
Clinical experiment divides three parts:
(1) animal acute toxicity and chronic toxicity experiment:
1, animal acute toxicity test
Medicine: the embodiment of the present invention 1, embodiment 2 and embodiment 3 medicated tea add the medicated tea powder paste that rice flour is made.
Experimental animal: regular grade NIH mice, body weight 18g ± 2g, male and female half and half.
Method and result:
By three kinds of each 50g of medicated tea, add rice flour.Experiment mice is randomly divided into three groups of male and female half and half, respectively three kinds of medicated tea of feeding
Powder is stuck with paste, volume 1ml/10g body weight, and close observation 8 hours is also noted down, and continues to observe 7 days；In 7 days, mice is without death, OK
For vivaciously, food ration is as usual, and hair color light is without loose dirt, without fainting from fear addicted to saliva, and eye, mouth, nose, ear and crissum secretions without exception,
Without the rotten toe that docks.5 execution of selection from three groups respectively, finding of naked eye: the important organs such as the heart, liver, lung, gastric and thymus, not
See abnormal change, show that two kinds of these nutritive powders are all without acute toxicity.
2, long-term toxicity test for animals
Medicine: the embodiment of the present invention 1, embodiment 2 and embodiment 3 gained medicated tea add the medicated tea powder paste that rice flour is made.
Animal: regular grade SD rat, body weight 200g ± 10g, male and female half and half.
Method and result:
The configuration that three kinds of medicated tea powder are stuck with paste: be divided into high, medium and low three dosage groups, respectively the 200 of edible for patients amount, 100,
50g；Experimental mouse is randomly divided into three groups, and the medicated tea powder that feeding modulates continuously respectively is stuck with paste, and continuous feeding 40 days observes animal
General toxic reaction and the order of severity, place after death by rule of operation check each position, and carry out hematology, ALT, BUN and the heart,
The pathological examination of the main organs such as liver, spleen, lung, kidney, stomach；
Through long-term feeding, all there is not toxic reaction in two groups of rats.Growth promoter is good.Macroscopic appearance and main organs have no
Abnormal.Peripheral hemogram and Serum ALT, BUN compare with matched group without pathologic change.The pathological replacement heart, liver, spleen, lung, kidney, stomach
Deng the most significant change, it is understood that through proved by pathology, three kinds of medicated tea powder are stuck with paste and showed animal without chronic toxicity.
By two above toxicity test, it was demonstrated that the medicated tea that the present invention is made by embodiment 1, embodiment 2 and embodiment 3 is
Safety, have no side effect, can be used to clinical patients is carried out clinical trial.
3, the embodiment of the present invention drinks effect research:
(1) investigation method:
1. crowd is drunk: general population
2. Ganderwa: 20 days
3. number is drunk: 50 people
4. drinking method: 3 times for each person every day, each 300mL
5. index: after drinking, substantially sensation easily fatigue, lung have scorching, overabundant liver-fire, lung network of burning, bronchus spitting of blood, food stagnation
Do not disappear, anorexia, the transference cure such as middle gas not province, and mouthfeel is the most sour-sweet for effective；After drinking, sensation easily fatigue, lung have dry
Heat, overabundant liver-fire, lung network of burning, bronchus spitting of blood；Food stagnation does not disappears, anorexia, middle gas do not save remission, and mouthfeel is the sourest
Sweet, it is designated as effectively.It is invalid to be then designated as without obvious comfort after drinking.
(2) survey result
Survey result is shown in Table 1.Be test result indicate that by table 1, embodiment 1,2,3 has the respondent of 98% to feel that the present invention is carried
The beverage mouthfeel of confession is the most sour-sweet, and above-mentioned clinical symptom disappearance or be eased, the respondent of only 2% drink after without substantially
Increase comfort.
The each embodiment of table 1 drinks effect research table
| Group/effect | Obvious effective rate (number) | Effective percentage (number) | Inefficiency (number) |
| Embodiment 1 | 44%(22) | 54%(27) | 2%(1) |
| Embodiment 2 | 42%(21) | 56%(28) | 2%(1) |
| Embodiment 3 | 42%(21) | 56%(28) | 2%(1) |
Embodiment contrast groups A
Comparative example 4,5,6 is added without the nutrition such as new fresh Herba Dendrobii, Fructus Vitis viniferae, Mel, water soluble dietary fiber and Oleum Vitis viniferae and becomes
Point, according to the raw material that the Chinese medicine part of embodiment 1,2,3 above is original, preparation for processing is traditional side of boiling
Method；The investigation method of using method and using effect is with above.
Table 2 embodiment contrast groups A drinks effect research
| Group/effect | Obvious effective rate (number) | Effective percentage (number) | Inefficiency (number) |
| Comparative example 4 | 36%(18) | 40%(20) | 24%(12) |
| Comparative example 5 | 40%(20) | 40%(20) | 20%(10) |
| Comparative example 6 | 46%(23) | 34%(17) | 20%(10) |
Embodiment contrast groups B
Comparative example 7,8,9 is added without the nutrition such as new fresh Herba Dendrobii, Fructus Vitis viniferae, Mel, water soluble dietary fiber and Oleum Vitis viniferae and becomes
Point, according to the raw material that the Chinese medicine part of embodiment 1,2,3 above is original, preparation for processing uses in embodiment 1
The preparation processing method of step E；The investigation method of using method and using effect is with above.
Table 3 embodiment contrast groups B drinks effect research
| Group/effect | Obvious effective rate (number) | Effective percentage (number) | Inefficiency (number) |
| Comparative example 7 | 32%(16) | 56%(28) | 12%(6) |
| Comparative example 8 | 28%(14) | 52%(31) | 10%(5) |
| Comparative example 9 | 36%(18) | 52%(26) | 12%(6) |
Embodiment contrast groups C
The processing method of comparative example 10,11,12 respectively corresponding embodiment 1,2,3 and formula, different be formula in
Without Air Bladder pseudosciaenae seu Acipenser composition；The investigation method of using method and using effect is with above.
Table 4 embodiment contrast groups C drinks effect research
| Group/effect | Obvious effective rate (number) | Effective percentage (number) | Inefficiency (number) |
| Comparative example 10 | 44%(22) | 46%(23) | 10%(5) |
| Comparative example 11 | 38%(19) | 50%(25) | 12%(6) |
| Comparative example 12 | 40%(20) | 48%(24) | 12%(6) |
Conclusion:
Contrasted by table 2 and table 1 and can be seen that
The inefficient number of embodiment contrast groups A is about 10 times of embodiment 1,2,3；This shows Chinese crude drug formula of the present invention
And between the nutritional labeling such as water soluble dietary fiber and Oleum Vitis viniferae, creating the most collaborative pharmacological action, aqueous soluble dietary is fine
Dimension increases effect of the wriggling of the intestines and stomach and promotes the human body absorption to ingredient, it is ensured that metabolic waste normally excretes, additionally
The anthocyanidin that contains in Pericarpium Vitis viniferae, resveratrol, have strong anti-oxidation, mutation, alleviate hepatosis, protection cardiovascular etc.
Function, strengthens immune system ability；Associate with Chinese medicine and improve assimilation effect and improve the mouthfeel of Chinese medicine, through the essence of the present invention simultaneously
The extraction of heart configuration and at utmost ingredient, Chinese crude drug formula of the present invention and preparation method occur in that beat all technology
Effect.
Table 2 and table 3 contrast can be seen that
About inefficient number is embodiment contrast groups B 2 times of embodiment contrast groups A, embodiment contrast groups B and traditional
Embodiment contrast groups A of boiling method has compared significant raising at therapeutic effect, and this shows that Chinese crude drug of the present invention is through step
The preparation processing method of rapid E has had significant raising than traditional boiling method, the extraction degree of active ingredient.
Table 1 is compared with table 4:
The formula of embodiment contrast groups C does not contains Air Bladder pseudosciaenae seu Acipenser, and the invalid number of embodiment contrast groups C is 5 times of left sides of embodiment 1,2,3
Right；And effective percentage number has and has declined；Containing abundant collagen protein and omega 3 unsaturated fatty acid in Air Bladder pseudosciaenae seu Acipenser, right
Blood fat controls useful, can strengthen gastrointestinal digestive and absorptive functions, improves appetite, is conducive to preventing and treating inappetence, anorexia, digestion
The diseases such as bad, abdominal distention, constipation, show Air Bladder pseudosciaenae seu Acipenser serve in formula collaborative and priming return through effect, Air Bladder pseudosciaenae seu Acipenser is in formula
Application effect achieves unexpected technique effect.
In sum, a kind of suppressing the hyperactive liver lung heat clearing peaceful network hemostasis beverage that the present invention provides has sour-sweet mouthfeel, has again simultaneously
Have treatment easily tired, lung have scorching, overabundant liver-fire, lung network of burning, bronchus spitting of blood, food stagnation do not disappear, anorexia, middle gas not
The merit of province, improves body immunity, defying age, eliminating toxin and beautifying the skin, nourishing taste, drops three-hypers, prevents and treats diabetes and anti-cancer, anticancer etc.
Aspect is the most powerful.And all raw materials is all from medicine-food two-purpose natural plants, have no side effect.
The above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art
For Yuan, under the premise without departing from the principles of the invention, it is also possible to make some improvements and modifications, these improvements and modifications also should
It is considered as protection scope of the present invention.
Claims (5)
1. a suppressing the hyperactive liver lung heat clearing peaceful network hemostasis beverage, it is characterised in that be made up of the raw material of following weight portion: new fresh Herba Dendrobii 10-
20 parts, Fructus Vitis viniferae 10-20 part, Folium Mori 5-15 part, Cortex Lycii 5-15 part, Radix Glycyrrhizae 5-15 part, Radix Rehmanniae 8-15 part, Radix Sanguisorbae 5-10 part,
Folium Eriobotryae 5-15 part, Radix Scutellariae 5-12 part, Colla Corii Asini 5-15 part, Nodus Nelumbinis Rhizomatis 5-16 part, Radix Peucedani 5-15 part, Rhizoma Pinelliae 5-15 part, Air Bladder pseudosciaenae seu Acipenser 5-10
Part, Mel, water are appropriate；
The preparation processing method of described a kind of suppressing the hyperactive liver lung heat clearing peaceful network hemostasis beverage, comprises the following steps；
A, fresh for Herba Dendrobii bar is put into service sink, remove surface clay stain, the fresh bar of screening high-quality Herba Dendrobii, dry standby；
B, fresh for the Herba Dendrobii cleaned up bar is put into microwave oven, keep temperature 50-60 DEG C, carry out heating 10 minutes, then take
Go out to put into rotating centrifugal juice extractor, carry out three times and squeeze the juice, add the alcohol content of Herba Dendrobii fresh bar weight 0.1-0.5 times for the first time
The Chinese liquor of 52-60 DEG C, time 10-15min, the rotating speed of juice extractor is 20～30r/s；After standing 10 minutes, add the fresh bar of Herba Dendrobii
The distilled water of weight 2-3 times, for the second time juice extractor time 10-15min, juice extractor rotating speed is 80～100r/s, stands 10min；
After carry out third time squeeze the juice, add Herba Dendrobii fresh bar weight 3-5 times distilled water, time 20-30min, juice extractor rotating speed be 100～
150r/s, separates fresh for Herba Dendrobii bar juice with fiber filter, makes the fiber separation rate of the fresh bar of Herba Dendrobii reach more than 95%, cell damage
Rate reaches more than 80%, obtains new fresh Herba Dendrobii juice and Herba Dendrobii fresh bar fiber；The warm water that new fresh grape is put into 50-60 DEG C again cleans dry
After Jing, Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae are separated stand-by；
C, Herba Dendrobii fresh bar juice is put into and is put in pressure pan with Fructus Vitis viniferae meat, keeps pressure 0.5MP, temperature to keep 100-150 in tank
Degree, carries out infusion 10 minutes, obtains Matrix Solution I standby；
D, fresh for the Herba Dendrobii of separation bar fiber and Pericarpium Vitis viniferae are put into unglazed hermetically sealed can, in hermetically sealed can, add that to be equivalent to Herba Dendrobii fresh
Bar fiber and the Mel of Pericarpium Vitis viniferae gross weight 20-30% and the distilled water of 5-10 times of weight, stirring is smashed to 100 mesh, at 30-35
Seal at a temperature of DEG C and preserve 24h, sterilizing, filter, put into unglazed hermetically sealed can, obtain Matrix Solution standby；After extracting Matrix Solution
It is the cellulase of 0.5-0.7% that Pericarpium Vitis viniferae and Herba Dendrobii fresh bar fiber add mass volume ratio, adds the water of the mass ratio of 1:10,
Keep 35 DEG C, water soluble dietary fiber can be extracted further after 24h enzymolysis, water soluble dietary fiber is added Matrix Solution
Obtain Matrix Solution II；
E, take Folium Mori, Cortex Lycii, Radix Glycyrrhizae, the Radix Rehmanniae, Radix Sanguisorbae, Folium Eriobotryae, Radix Scutellariae, Colla Corii Asini, Nodus Nelumbinis Rhizomatis, south Plantula Papaveris, Radix Peucedani, the Rhizoma Pinelliae,
Air Bladder pseudosciaenae seu Acipenser；After mix homogeneously adds 30-60 DEG C of warm water soaking 10 minutes, putting into reach in freezer ,-10～-20 DEG C, freezing 10-20 divides
Clock, forms freezing medicine block, freezing medicine block boiling is extracted 3 times, add 1-2 times amount water for the first time, and temperature keeps 100-120
DEG C, carry out infusion 10-20 minute；Second time adds 4-6 times amount water, and temperature keeps 80-100 DEG C, carries out infusion 10 minutes；For the third time
Adding 6-10 times amount water, temperature keeps 120-150 DEG C, carries out infusion 30 minutes, filters, is concentrated into the 1/2 of original volume, obtains matrix
Solution III is standby；
F, take Matrix Solution I through instantaneous high-temperature 110-130 DEG C, 1-2 minute, put into material-compound tank；Take Matrix Solution II through mesh
Number be 100 mesh fine filter filter after put into material-compound tank；Take Matrix Solution III again to put into after the fine filter filter that mesh number is 60 mesh
In material-compound tank；
G, by Semen Vitis viniferae through vacuum outgas, then use CO2 supercritical fluid extraction, the condition of CO2 supercritical fluid extraction is:
Extracting pressure 45MPa, extraction temperature 35-45 DEG C, extraction time 30min, isolated Oleum Vitis viniferae；
H, three kinds of Matrix Solutions are stirring evenly and then adding into Oleum Vitis viniferae at material-compound tank, seal through bottle capper and load in vial,
Packaged vial puts into temperature 100～120 DEG C, 1.5MP, sterilization in 15～21 minutes steam ovens, packaging, vanning.
A kind of suppressing the hyperactive liver lung heat clearing peaceful network hemostasis beverage the most according to claim 1, it is characterised in that step B) in, fresh Portugal
After grape clean up, put into reach in freezer ,-10～-20 DEG C freezing 5-10 minute, make Fructus Vitis viniferae freeze, take out after nature thaws,
Carry out Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae detached job again.
A kind of suppressing the hyperactive liver lung heat clearing peaceful network hemostasis beverage the most according to claim 1, it is characterised in that step H) described in dispensing
Tank endobasal-body solution I, Matrix Solution II, Matrix Solution III, the weight proportion of Oleum Vitis viniferae are 10:0.2～0.8:5～10:
0.5。
A kind of suppressing the hyperactive liver lung heat clearing peaceful network hemostasis beverage the most according to claim 1, it is characterised in that former by following weight portion
Material is made: new fresh Herba Dendrobii 10 parts, Fructus Vitis viniferae 10 parts, 5 parts of Folium Mori, Cortex Lycii 5 parts, Radix Glycyrrhizae 5 parts, 8 parts of the Radix Rehmanniae, Radix Sanguisorbae 5 parts, Folium Eriobotryae
5 parts of leaf, Radix Scutellariae 5 parts, 5 parts of Colla Corii Asini, Nodus Nelumbinis Rhizomatis 5 parts, Radix Peucedani 5 parts, the Rhizoma Pinelliae 5 parts, 5 parts of Air Bladder pseudosciaenae seu Acipenser, Mel, water are appropriate.
A kind of suppressing the hyperactive liver lung heat clearing peaceful network hemostasis beverage the most according to claim 1, it is characterised in that former by following weight portion
Material is made: new fresh Herba Dendrobii 20 parts, Fructus Vitis viniferae 20 parts, 15 parts of Folium Mori, Cortex Lycii 15 parts, Radix Glycyrrhizae 15 parts, 15 parts of the Radix Rehmanniae, Radix Sanguisorbae 10
Part, Folium Eriobotryae 15 parts, Radix Scutellariae 12 parts, 15 parts of Colla Corii Asini, Nodus Nelumbinis Rhizomatis 16 parts, Radix Peucedani 15 parts, the Rhizoma Pinelliae 15 parts, 10 parts of Air Bladder pseudosciaenae seu Acipenser, Mel, water are fitted
Amount.
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| CN201610234365.XA Pending CN106165802A (en) | 2016-04-17 | 2016-04-17 | A kind of suppressing the hyperactive liver lung heat clearing peaceful network hemostasis beverage and preparation processing method |
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103300450A (en) * | 2013-06-14 | 2013-09-18 | 浙江大学 | Preparation method of raw dendrobium officinale pulp beverage |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103300450A (en) * | 2013-06-14 | 2013-09-18 | 浙江大学 | Preparation method of raw dendrobium officinale pulp beverage |
Non-Patent Citations (2)
| Title |
|---|
| 宋芳等: "超临界二氧化碳萃取葡萄籽油及其脂肪酸的分析", 《中国食品工业》 * |
| 李文亮等: "《千家妙方上》", 31 July 1982, 战士出版社 * |
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