CN106166279A - A kind of blood-activating analgetic treatment gastric ulcer medicated tea and preparation processing method - Google Patents
A kind of blood-activating analgetic treatment gastric ulcer medicated tea and preparation processing method Download PDFInfo
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- CN106166279A CN106166279A CN201610234309.6A CN201610234309A CN106166279A CN 106166279 A CN106166279 A CN 106166279A CN 201610234309 A CN201610234309 A CN 201610234309A CN 106166279 A CN106166279 A CN 106166279A
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Abstract
The invention discloses a kind of blood-activating analgetic treatment gastric ulcer medicated tea of the present invention, be made up of the raw material of following weight portion: Rhizoma Coptidis 5 15 parts, the Rhizoma Pinelliae 5 15 parts, Radix Paeoniae Rubra 5 12 parts, the Radix Paeoniae Alba 39 parts, Os Sepiae 5 12 parts, Bulbus Fritillariae Uninbracteatae 5 10 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10 16 parts, Rhizoma Corydalis 5 15 parts, Concha Arcae 6 15 parts, the Radix Aucklandiae 5 10 parts, Pericarpium Citri Reticulatae 5 10 parts, Radix Et Rhizoma Rhei 5 10 parts, 5 10 parts of Rhizoma Zingiberis Recens, Fructus Aurantii Immaturus 5 10 parts, Radix Bupleuri 5 10 parts.The invention have the advantage that inventive formulation blood-activating analgetic, blood circulation promoting and blood stasis dispelling, relieving gastric hyperacidity to alleviate stomachache, treat gastric ulcer medicine, improve body immunity, defying age, eliminating toxin and beautifying the skin, nourishing taste, the merit of resisting fatigue.
Description
Technical field
The present invention relates to a kind of blood-activating analgetic treatment gastric ulcer medicated tea, in particular, relate to a kind of blood-activating analgetic and control
Treat gastric ulcer herb tea formula and preparation method thereof technical field.
Background technology
Peptic Ulcers or peptic ulcer are a kind of common digestive tract disease, can betide esophagus, stomach or duodenum, also
Can betide near stomach-intestinal anastomosis mouth or contain in the Meckel diverticulum of gastric mucosa, because gastric ulcer and duodenal ulcer
Most common, therefore general so-called peptic ulcer refers to gastric ulcer.Why it is referred to as peptic ulcer, is because previously recognizing
Mucosa autodigestion is formed due to gastric acid and pepsin by gastric ulcer and duodenal ulcer, in fact gastric acid and
Pepsin is the one of the main reasons of ulcer, and also other reasons can form peptic ulcer.Epigastrium pain
It it is the cardinal symptom of primary disease.It is positioned at epigastrium, it is possible to after occurring in left upper abdomen or breastbone, xiphoid-process more.Often in dull pain, dull pain,
Distending pain, burn sample pain.The pain of gastric ulcer is many to be occurred in after the meal 1 hour, gradually alleviated after 1～2 hour, until under eat into
The above-mentioned rhythm and pace of moving things is reappeared again after food.Some patients can be asymptomatic, or using complication such as hemorrhage, perforation as onset symptoms, gastral cavilty is acute
Bitterly, bitter, bitter taste sour taste in the mouth, xerostomia are vomitted and smelly, constipation with dry stool, qi depression to blood stasis.
The most traditional beverage, only focuses on mouthfeel, is of low nutritive value, and does not only have blood-activating analgetic, blood circulation promoting and blood stasis dispelling, antacid
Bitterly, treatment gastric ulcer medicine, improve body immunity, defying age, eliminating toxin and beautifying the skin, nourishing taste, drop three-hypers, prevent and treat diabetes and anti-
Cancer, the function of the aspect such as anticancer, it is impossible to releasing the sufferings of client, and traditional herbal tea is by Traditional medicine infusion, flavour of a drug weight mouthfeel is poor,
Cannot preserve for a long time.The most not yet occur a kind of in good taste, improve self and increase the wriggling of the intestines and stomach, cure the disease and strengthen simultaneously
The beverage of body immunity.
Summary of the invention
The present invention is directed to the deficiency of existing product, and provide a kind of fresh juice beverage to regulate the effect of human physiological functions,
This beverage have be easily absorbed by the human body, medicinal function is notable, delicious flavour, good mouthfeel, improve self and increase the wriggling of the intestines and stomach,
Cure the disease and strengthen a kind of blood-activating analgetic treatment gastric ulcer medicated tea of the advantages such as body immunity simultaneously.
A kind of blood-activating analgetic treatment gastric ulcer medicated tea, is made up of the raw material of following weight portion: Rhizoma Coptidis 5-15 part, Rhizoma Pinelliae 5-15
Part, Radix Paeoniae Rubra 5-12 part, Radix Paeoniae Alba 3-9 part, Os Sepiae 5-12 part, Bulbus Fritillariae Uninbracteatae 5-10 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 10-16 part, Rhizoma Corydalis 5-15 part, Concha Arcae
6-15 part, Radix Aucklandiae 5-10 part, Pericarpium Citri Reticulatae 5-10 part, Radix Et Rhizoma Rhei 5-10 part, Rhizoma Zingiberis Recens 5-10 part, Fructus Aurantii Immaturus 5-10 part, Radix Bupleuri 5-10 part, Air Bladder pseudosciaenae seu Acipenser
5-10 part, new fresh Herba Dendrobii 10-20 part, Fructus Vitis viniferae 10-20 part, Mel, water are appropriate.
The preparation processing method of described a kind of blood-activating analgetic treatment gastric ulcer medicated tea, comprises the following steps；
A, fresh for Herba Dendrobii bar is put into service sink, remove surface clay stain, the fresh bar of screening high-quality Herba Dendrobii, dry standby；
B, fresh for the Herba Dendrobii cleaned up bar is put into microwave oven, keep temperature 50-60 DEG C, carry out heating 10 minutes, then take
Go out to put into rotating centrifugal juice extractor, carry out three times and squeeze the juice, add the alcohol content of Herba Dendrobii fresh bar weight 0.1-0.5 times for the first time
The Chinese liquor of 52-60 DEG C, time 10-15min, the rotating speed of juice extractor is 20～30r/s；After standing 10 minutes, add the fresh bar of Herba Dendrobii
The distilled water of weight 2-3 times, for the second time juice extractor time 10-15min, juice extractor rotating speed is 80～100r/s, stands 10min；
After carry out third time squeeze the juice, add Herba Dendrobii fresh bar weight 3-5 times distilled water, time 20-30min, juice extractor rotating speed be 100～
150r/s, separates fresh for Herba Dendrobii bar juice with fiber filter, makes the fiber separation rate of the fresh bar of Herba Dendrobii reach more than 95%, cell damage
Rate reaches more than 80%, obtains new fresh Herba Dendrobii juice and Herba Dendrobii fresh bar fiber；The warm water that new fresh grape is put into 50-60 DEG C again cleans dry
After Jing, Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae are separated stand-by；
C, Herba Dendrobii fresh bar juice is put into and is put in pressure pan with Fructus Vitis viniferae meat, keeps pressure 0.5MP, temperature to keep 100-150 in tank
Degree, carries out infusion 10 minutes, obtains Matrix Solution I standby；
D, fresh for the Herba Dendrobii of separation bar fiber and Pericarpium Vitis viniferae are put into unglazed hermetically sealed can, in hermetically sealed can, add that to be equivalent to Herba Dendrobii fresh
Bar fiber and the Mel of Pericarpium Vitis viniferae gross weight 20-30% and the distilled water of 5-10 times of weight, stirring is smashed to 100 mesh, at 30-35
Seal at a temperature of DEG C and preserve 24h, sterilizing, filter, put into unglazed hermetically sealed can, obtain Matrix Solution standby；After extracting Matrix Solution
It is the cellulase of 0.5-0.7% that Pericarpium Vitis viniferae and Herba Dendrobii fresh bar fiber add mass volume ratio, adds the water of the mass ratio of 1:10,
Keep 35 DEG C, water soluble dietary fiber can be extracted further after 24h enzymolysis, water soluble dietary fiber is added Matrix Solution
Obtain Matrix Solution II；
E, take mix homogeneously after Radix Et Rhizoma Rhei, Rhizoma Zingiberis Recens cleaning and sterilizing, respectively with 6 times of weight 85% mol ratio ethanol extractions 2 times, each 2
Hour, merge 2 Radix Et Rhizoma Rhei, Rhizoma Zingiberis Recens ethanol extracts, receive alcohol and to be evaporated to relative density at 40 DEG C be 1.15-1.35, system
The extract obtaining Radix Et Rhizoma Rhei is standby；
Os Sepiae, Concha Arcae, Radix Aucklandiae mix and blend are put into super micron mill, and super micron mill heating keeps 120 degree of 5-6 of temperature
Minute, carry out micronizing and obtain the ultra micro mixing fine powders of 300-400 mesh；
Take Rhizoma Coptidis, the Rhizoma Pinelliae, Radix Paeoniae Rubra, the Radix Paeoniae Alba, Bulbus Fritillariae Uninbracteatae, the Pseudobulbus Bletillae (Rhizoma Bletillae), Rhizoma Corydalis, Pericarpium Citri Reticulatae, Fructus Aurantii Immaturus, Radix Bupleuri, Air Bladder pseudosciaenae seu Acipenser, mix homogeneously adds 30-60
DEG C warm water soaking, after 10 minutes, puts into reach in freezer ,-10～-20 DEG C freezing 10-20 minute, forms freezing medicine block, by freezing
Medicine block and ultra micro mixing fine powders boiling are extracted 3 times, add 1-2 times amount water for the first time, and temperature keeps 100-120 DEG C, endures
Boil 10-20 minute；Second time adds 4-6 times amount water, and temperature keeps 80-100 DEG C, carries out infusion 10 minutes；Third time adds 6-10 times
Amount water, temperature keeps 120-150 DEG C, carries out infusion 30 minutes, filters, and is concentrated into the 1/2 of original volume, adds Radix Et Rhizoma Rhei, Rhizoma Zingiberis Recens
Extract, obtain Matrix Solution III standby；
F, take Matrix Solution I through instantaneous high-temperature 110-130 DEG C, 1-2 minute, put into material-compound tank；Take Matrix Solution II through mesh
Number be 100 mesh fine filter filter after put into material-compound tank；Take Matrix Solution III again to put into after the fine filter filter that mesh number is 60 mesh
In material-compound tank；
G, by Semen Vitis viniferae through vacuum outgas, then use CO2 supercritical fluid extraction, the condition of CO2 supercritical fluid extraction is:
Extracting pressure 45MPa, extraction temperature 35-45 DEG C, extraction time 30min, isolated Oleum Vitis viniferae；
H, three kinds of Matrix Solutions are stirring evenly and then adding into Oleum Vitis viniferae at material-compound tank, seal through bottle capper and load in vial,
Packaged vial puts into temperature 100～120 DEG C, 1.5MP, sterilization in 15～21 minutes steam ovens, packaging, vanning.
Further: step B) in, after new fresh grape cleans up, put into reach in freezer ,-10～-20 DEG C freezing 5-10 minute,
Make Fructus Vitis viniferae freeze, after taking out nature defrosting, then carry out Fructus Vitis viniferae meat and Pericarpium Vitis viniferae detached job.
Further: step H) described in material-compound tank endobasal-body solution I, Matrix Solution II, Matrix Solution III, Oleum Vitis viniferae
Weight proportion be 10:0.2～0.8:5～10:0.5.
Rhizoma Coptidis is bitter；Cold, heart channel；Liver Channel；Stomach warp；Large intestine channel, pathogenic fire purging, dampness, removing toxic substances, parasite killing.Row pyretic toxicity when controlling, typhoid fever,
Intenseness of heat is vexed, feeling of fullness vomiting, bacillary dysentery, and diarrhea of heat type is suffered from abdominal pain, and lung knot is pressed, and tells, is defeated in battle, hematochezia, quenches one's thirst, infantile malnutrition, ascariasis, pertussis, pharynx
Larynx swells and ache, acute catarrhal conjunctivitis, aphtha, skin sore, eczema, the burning hot wound of soup.
The Rhizoma Pinelliae, enters lung, spleen, stomach three warp, drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.
Radix Paeoniae Rubra, bitter, it is slightly cold.Return Liver Channel.There is clearing away heat and cooling blood, effect of blood circulation promoting and blood stasis dispelling.
The Radix Paeoniae Alba, suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating.For dizziness of having a headache, hypochondriac pain, stomachache, limb pain twin.
Os Sepiae, relieving gastric hyperacidity to alleviate stomachache, hemostasis, synthetism, bone defect healing, radioprotective, antitumor, antiulcer etc. act on.
Bulbus Fritillariae Uninbracteatae, relieving cough and resolving phlegm, the merit of heat clearing away eliminating stagnation.
The Pseudobulbus Bletillae (Rhizoma Bletillae), bitter in the mouth, sweet, puckery, cold in nature, return lung, liver, stomach warp.There is astringing to arrest bleeding, the merit of detumescence and promoting granulation, go out in being used for
The all cards of blood.
Rhizoma Corydalis, acrid in the mouth, hardship, warm in nature.There are promoting blood circulation to remove blood stasis, the function of promoting the circulation of QI pain relieving.
Concha Arcae, returns lung, stomach, Liver Channel.Expectorant blood stasis dispelling, hard masses softening and resolving, relieving gastric hyperacidity to alleviate stomachache.
The Radix Aucklandiae, the abdominal distention caused by stagnation of QI in spleen and stomach, lack of appetite vomiting, the hypochondriac pain caused for QI stagnation of the liver and galibladder, spleen invigorating disappears stagnant.
The stagnant gas of adjustable gastrointestinal.
Pericarpium Citri Reticulatae, bitter in the mouth, pungent, warm in nature.Return lung, spleen channel.Regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.
Radix Et Rhizoma Rhei, bitter, cold.Return spleen, stomach, large intestine, liver, pericardium channel.Heat and toxic materials clearing away, clearing away heat-fire, removing pathogenic heat from blood and toxic substance from the body, removing blood stasis leads to
Warp, dampness removing jaundice eliminating.
Rhizoma Zingiberis Recens, seasoning, warming middle-JIAO, also there are fabulous sterilization, antiinflammatory, expelling summer-heat, detoxifying effect.
Fructus Aurantii Immaturus, bitter, pungent, sour, temperature.Return spleen, stomach, large intestine channel, stop in stagnant；Feeling of fullness distending pain；Constipation；After dysentery
Weight；Blocked-up chest etc..
Radix Bupleuri, acrid in the mouth, hardship, cold nature.Reconciling superficies and interior, dispersing the stagnated live-QI to relieve the stagnation of QI, ascending up spleen-Qi and Yang, preventing the attack (or recurrence) of malaria of bringing down a fever, for cold, fever,
Alternate attack of chill and fever, distending pain in the chest and hypochondrium.
Fructus Vitis viniferae is the most delicious and tasty, and nutritive value is the highest, containing mineral calcium, potassium, phosphorus, ferrum and multiple in Fructus Vitis viniferae
Vitamin B1, vitamin B2, vitamin B6, vitamin C and Citrin etc., possibly together with the aminoacid of multiple needed by human body, multiple
Fruit acid contributes to digestion, suitably eats a little Fructus Vitis viniferae more, can be good for Pi stomach function regulating, and to neurasthenia, overfatigue is of great advantage and has.
The natural tradition medicinal and edible Chinese medicine above with multiple health care is share, blood-activating analgetic, blood circulation promoting and blood stasis dispelling, system
Acid pain relieving, treats gastric ulcer medicine, improves body immunity, defying age, eliminating toxin and beautifying the skin, nourishing taste, the merit of resisting fatigue.By greatly
The proportioning of the amount each component of experiment screening, scientific and reasonable；And whole preparation technology is rationally and extract drugs rate efficiency is high, can be very well
Ground retains the effective ingredient in raw material, does not bring any impurity, and sweet mouthfeel into, has no side effect.
The invention has the beneficial effects as follows:
1, the formula of the present invention, has promoting the production of body fluid to quench thirst, gastric acid secretion, helps digest, and health body-building has calm nerves and declines
Weak, lessen fatigue, containing various trace elements such as calcium, ferrum, zinc, selenium, sodium etc., raising body immunity, defying age, toxin expelling are supported
Face, nourish taste, three-hypers drops, to prevent and treat diabetes and anti-cancer, the aspect such as anticancer the most powerful, regulates human physiological functions.
2, the present invention is rich in anthocyanidin, it is possible to protection human body is from the damage of free radical, it is possible to strengthens blood vessel elasticity, relax
Blood vessel, increases systemic blood circulation, has certain blood pressure reduction effect；Immune system ability can be strengthened, there is strong anti-oxidation, resist
Suddenly change, alleviate the function such as hepatosis, protection cardiovascular；
3, add the Chinese herbal medicine such as Rhizoma Coptidis, the Rhizoma Pinelliae, Radix Paeoniae Rubra, the Radix Paeoniae Alba, Bulbus Fritillariae Uninbracteatae, the Pseudobulbus Bletillae (Rhizoma Bletillae), Rhizoma Corydalis, Pericarpium Citri Reticulatae, Fructus Aurantii Immaturus, Radix Bupleuri and there is blood stasis dispelling only
Bitterly, blood circulation promoting and blood stasis dispelling, relieving gastric hyperacidity to alleviate stomachache, treat gastric ulcer medicine, improve body immunity, defying age, eliminating toxin and beautifying the skin, nourishing taste, anti-
The functions such as fatigue.
4, the products taste that the production technology of the present invention and preparation method draw is sour-sweet tasty and refreshing, rich in dendrobium polysaccharide, has
The highest health care and medical value, long-term drink can with YIN nourishing skin care, change skin colour, defying age, life lengthening, and
Carrying and drink conveniently, improve self and increase the wriggling of the intestines and stomach, cure the disease and strengthen the beverage of body immunity simultaneously, the shelf-life is up to 1-
2 years.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further described, in order to those skilled in the art knows more about
The present invention, but and it is not so limited the present invention.
Embodiment 1
A kind of blood-activating analgetic treatment gastric ulcer medicated tea, is made up of the raw material of following weight portion: Rhizoma Coptidis 10 parts, the Rhizoma Pinelliae 10 parts, Radix Paeoniae Rubra
10 parts, the Radix Paeoniae Alba 8 parts, Os Sepiae 10 parts, Bulbus Fritillariae Uninbracteatae 8 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 12 parts, Rhizoma Corydalis 12 parts, Concha Arcae 12 parts, the Radix Aucklandiae 8 parts, Pericarpium Citri Reticulatae 8 parts,
Radix Et Rhizoma Rhei 8 parts, 8 parts of Rhizoma Zingiberis Recens, Fructus Aurantii Immaturus 10 parts, Radix Bupleuri 8 parts, 8 parts of Air Bladder pseudosciaenae seu Acipenser, new fresh Herba Dendrobii 15 parts, Fructus Vitis viniferae 15 parts, Mel, water are appropriate.
The preparation processing method of a kind of blood-activating analgetic treatment gastric ulcer medicated tea, described preparation method comprises the following steps；
A, fresh for Herba Dendrobii bar is put into service sink, remove surface clay stain, the fresh bar of screening high-quality Herba Dendrobii, dry standby；
Fresh for the Herba Dendrobii cleaned up bar is put into microwave oven by B, keeps temperature 50-60 DEG C, carries out heating 10 minutes, further take out
Put into rotating centrifugal juice extractor, carry out three times and squeeze the juice, add the alcohol content 52 of Herba Dendrobii fresh bar weight 0.1-0.5 times for the first time
DEG C Chinese liquor, time 15min, the rotating speed of juice extractor is 30r/s；After standing 10 minutes, add the steaming of Herba Dendrobii fresh bar weight 2.5 times
Distilled water, for the second time juice extractor time 15min, juice extractor rotating speed is 80r/s, stands 10min；After carry out third time squeeze the juice, add
The distilled water of Herba Dendrobii fresh bar weight 3-5 times, time 30min, juice extractor rotating speed is 150r/s, by fresh for Herba Dendrobii bar juice and fiber mistake
Filter separate, make the fiber separation rate of the fresh bar of Herba Dendrobii reach more than 95%, broken cell rate reaches more than 80%, obtain new fresh Herba Dendrobii juice and
Herba Dendrobii fresh bar fiber；Again new fresh grape is put into after the warm water of 55 DEG C cleans up, Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae are separated
Stand-by；After new fresh grape cleans up, put into reach in freezer ,-10 ~-20 DEG C of freezings 10 minutes, make Fructus Vitis viniferae freeze, take out certainly
After so thawing, then carry out Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae detached job.
C, Herba Dendrobii fresh bar juice is put into and is put in pressure pan with Fructus Vitis viniferae meat, keeps pressure 0.5MP, temperature to keep 120 in tank
Degree, carries out infusion 10 minutes, obtains Matrix Solution I standby；
D, fresh for the Herba Dendrobii of separation bar fiber and Pericarpium Vitis viniferae are put into unglazed hermetically sealed can, in hermetically sealed can, add that to be equivalent to Herba Dendrobii fresh
Bar fiber and the Mel of Pericarpium Vitis viniferae gross weight 20-30% and the distilled water of 6 times of weight, stirring is smashed to 100 mesh, 30-35 DEG C of temperature
Degree lower seal preserves 24h, sterilizing, filters, puts into unglazed hermetically sealed can, obtain Matrix Solution standby；Extract the Fructus Vitis viniferae after Matrix Solution
It is the cellulase of 0.5-0.7% that skin and Herba Dendrobii fresh bar fiber add mass volume ratio, adds the water of the mass ratio of 1:10, keeps
35 DEG C, water soluble dietary fiber can be extracted after 24h enzymolysis further, water soluble dietary fiber is added Matrix Solution and obtains
Matrix Solution II；Rich in anthocyanidin in Pericarpium Vitis viniferae, it is possible to protection human body is from the damage of free radical, it is possible to enhancing blood vessel elasticity,
Lax blood vessel, increases systemic blood circulation, has certain blood pressure reduction effect；Immune system ability can be strengthened, there is strong antioxygen
Change, mutation, alleviate hepatosis, protection function, Pericarpium Vitis viniferae and the Herba Dendrobii fresh bar fiber such as cardiovascular together with stir smash through
Anthocyanidin mentioned by hydromel, can protect the quality of anthocyanidin while farthest extracting anthocyanidin.By water solublity meals
Food fiber adds Matrix Solution and obtains Matrix Solution II, can increase effect of the wriggling of the intestines and stomach, it is ensured that metabolic waste is normally discharged
External；Adsorbing various metabolic waste, be allowed to normally excrete, the comprehensive utilization value improving Herba Dendrobii improves human body centering simultaneously
The absorption of medicine composition.
E, take mix homogeneously after Radix Et Rhizoma Rhei, Rhizoma Zingiberis Recens cleaning and sterilizing, respectively with 6 times of weight 85% mol ratio ethanol extractions 2 times, often
Secondary 2 hours, merge 2 Radix Et Rhizoma Rhei, Rhizoma Zingiberis Recens ethanol extracts, receive alcohol and to be evaporated to relative density at 40 DEG C be 1.15-1.35,
The extract preparing Radix Et Rhizoma Rhei is standby；
Os Sepiae, Concha Arcae, Radix Aucklandiae mix and blend are put into super micron mill, and super micron mill heating keeps 120 degree of 5-6 of temperature
Minute, carry out micronizing and obtain the ultra micro mixing fine powders of 300-400 mesh；
Take Rhizoma Coptidis, the Rhizoma Pinelliae, Radix Paeoniae Rubra, the Radix Paeoniae Alba, Bulbus Fritillariae Uninbracteatae, the Pseudobulbus Bletillae (Rhizoma Bletillae), Rhizoma Corydalis, Pericarpium Citri Reticulatae, Fructus Aurantii Immaturus, Radix Bupleuri, Air Bladder pseudosciaenae seu Acipenser, mix homogeneously adds 30-60
DEG C warm water soaking, after 10 minutes, puts into reach in freezer ,-10～-20 DEG C freezing 10-20 minute, forms freezing medicine block, by freezing
Medicine block and ultra micro mixing fine powders boiling are extracted 3 times, add 1-2 times amount water for the first time, and temperature keeps 100-120 DEG C, endures
Boil 10-20 minute；Second time adds 4-6 times amount water, and temperature keeps 80-100 DEG C, carries out infusion 10 minutes；Third time adds 6-10 times
Amount water, temperature keeps 120-150 DEG C, carries out infusion 30 minutes, filters, and is concentrated into the 1/2 of original volume, adds Radix Et Rhizoma Rhei, Rhizoma Zingiberis Recens
Extract, obtain Matrix Solution III standby；
The hard to bear medicine boiled is pulverized and improves its extract drugs efficiency, make whole formula drug effect farthest be utilized.
F, take Matrix Solution I through instantaneous high-temperature 120 DEG C, 1-2 minute, put into material-compound tank；Take Matrix Solution II through mesh
Number be 100 mesh fine filter filter after put into material-compound tank；Take Matrix Solution III again to put into after the fine filter filter that mesh number is 60 mesh
In material-compound tank；
G, by Semen Vitis viniferae through vacuum outgas, then use CO2 supercritical fluid extraction, the condition of CO2 supercritical fluid extraction is:
Extracting pressure 45MPa, extraction temperature 35-45 DEG C, extraction time 30min, isolated Oleum Vitis viniferae；Supercritical extraction can be
Extract under room temperature 37 DEG C and CO2 gas blanket, effectively prevent oxidation and the loss of heat-sensitive substance.Therefore,
The effective ingredient of medicinal plants is remain in extract, and can be high boiling point, low volatility, the easy material being pyrolyzed the lowest
Extract under its boiling temperature；
H, three kinds of Matrix Solutions are stirring evenly and then adding into Oleum Vitis viniferae at material-compound tank, and described material-compound tank endobasal-body solution I, matrix are molten
Liquid II, Matrix Solution III, the weight proportion of Oleum Vitis viniferae are 10:0.5:6:0.5.Sealing through bottle capper loads in vial,
Packaged vial puts into temperature 100～120 DEG C, 1.5MP, sterilization in 15～21 minutes steam ovens, packaging, vanning,
Carrying and drink conveniently, the shelf-life is up to 1-2.
Embodiment 2
A kind of blood-activating analgetic treatment gastric ulcer medicated tea, is made up of the raw material of following weight portion: Rhizoma Coptidis 5 parts, the Rhizoma Pinelliae 5 parts, Radix Paeoniae Rubra 5
Part, the Radix Paeoniae Alba 3 parts, Os Sepiae 5 parts, Bulbus Fritillariae Uninbracteatae 5 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10 parts, Rhizoma Corydalis 5 parts, Concha Arcae 6 parts, the Radix Aucklandiae 5 parts, Pericarpium Citri Reticulatae 5 parts, Radix Et Rhizoma Rhei 5
Part, 5 parts of Rhizoma Zingiberis Recens, Fructus Aurantii Immaturus 5 parts, Radix Bupleuri 5 parts, 5 parts of Air Bladder pseudosciaenae seu Acipenser, new fresh Herba Dendrobii 10 parts, Fructus Vitis viniferae 10 parts, Mel, water appropriate.Processing side
Method is with embodiment 1.
Embodiment 3
A kind of blood-activating analgetic treatment gastric ulcer medicated tea, is made up of the raw material of following weight portion: Rhizoma Coptidis 15 parts, the Rhizoma Pinelliae 15 parts, Radix Paeoniae Rubra
12 parts, the Radix Paeoniae Alba 9 parts, Os Sepiae 12 parts, Bulbus Fritillariae Uninbracteatae 10 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 16 parts, Rhizoma Corydalis 15 parts, Concha Arcae 15 parts, the Radix Aucklandiae 10 parts, Pericarpium Citri Reticulatae 10
Part, Radix Et Rhizoma Rhei 10 parts, 10 parts of Rhizoma Zingiberis Recens, Fructus Aurantii Immaturus 10 parts, Radix Bupleuri 10 parts, 10 parts of Air Bladder pseudosciaenae seu Acipenser, new fresh Herba Dendrobii 20 parts, Fructus Vitis viniferae 20 parts, Mel, water
In right amount.Processing method is with embodiment 1.
Clinical experiment divides three parts:
(1) animal acute toxicity and chronic toxicity experiment:
1, animal acute toxicity test
Medicine: the embodiment of the present invention 1, embodiment 2 and embodiment 3 medicated tea add the medicated tea powder paste that rice flour is made.
Experimental animal: regular grade NIH mice, body weight 18g ± 2g, male and female half and half.
Method and result:
By three kinds of each 50g of medicated tea, add rice flour.Experiment mice is randomly divided into three groups of male and female half and half, respectively three kinds of medicated tea of feeding
Powder is stuck with paste, volume 1ml/10g body weight, and close observation 8 hours is also noted down, and continues to observe 7 days；In 7 days, mice is without death, OK
For vivaciously, food ration is as usual, and hair color light is without loose dirt, without fainting from fear addicted to saliva, and eye, mouth, nose, ear and crissum secretions without exception,
Without the rotten toe that docks.5 execution of selection from three groups respectively, finding of naked eye: the important organs such as the heart, liver, lung, gastric and thymus, not
See abnormal change, show that two kinds of these nutritive powders are all without acute toxicity.
2, long-term toxicity test for animals
Medicine: the embodiment of the present invention 1, embodiment 2 and embodiment 3 gained medicated tea add the medicated tea powder paste that rice flour is made.
Animal: regular grade SD rat, body weight 200g ± 10g, male and female half and half.
Method and result:
The configuration that three kinds of medicated tea powder are stuck with paste: be divided into high, medium and low three dosage groups, respectively the 200 of edible for patients amount, 100,
50g；Experimental mouse is randomly divided into three groups, and the medicated tea powder that feeding modulates continuously respectively is stuck with paste, and continuous feeding 40 days observes animal
General toxic reaction and the order of severity, place after death by rule of operation check each position, and carry out hematology, ALT, BUN and the heart,
The pathological examination of the main organs such as liver, spleen, lung, kidney, stomach；
Through long-term feeding, all there is not toxic reaction in two groups of rats.Growth promoter is good.Macroscopic appearance and main organs have no
Abnormal.Peripheral hemogram and Serum ALT, BUN compare with matched group without pathologic change.The pathological replacement heart, liver, spleen, lung, kidney, stomach
Deng the most significant change, it is understood that through proved by pathology, three kinds of medicated tea powder are stuck with paste and showed animal without chronic toxicity.
By two above toxicity test, it was demonstrated that the medicated tea that the present invention is made by embodiment 1, embodiment 2 and embodiment 3 is
Safety, have no side effect, can be used to clinical patients is carried out clinical trial.
3, the embodiment of the present invention drinks effect research:
(1) investigation method:
1. crowd is drunk: general population
2. Ganderwa: 30 days
3. number is drunk: 50 people
4. drinking method: 3 times for each person every day, after meal each 500mL
5. index: after drinking substantially gastral cavilty severe pain, vomit bitter, bitter taste sour taste in the mouth, xerostomia and smelly, constipation with dry stool, qi depression to blood stasis etc.
Transference cure, and mouthfeel is the most sour-sweet for effective；Drink rear gastral cavilty severe pain, vomit bitter, bitter taste sour taste in the mouth, xerostomia and dry stool smelly, big
The remissions such as knot, qi depression to blood stasis, inappetence, and mouthfeel is the most sour-sweet, is designated as effectively.Then remember without obvious comfort after drinking
For invalid.
(2) survey result
Survey result is shown in Table 1.Be test result indicate that by table 1, embodiment 1,2,3 has the respondent of 98% to feel that the present invention is carried
The beverage mouthfeel of confession is the most sour-sweet, and above-mentioned clinical symptom disappearance or be eased, the respondent of only 2% drink after without substantially
Increase comfort.
The each embodiment of table 1 drinks effect research table
| Group/effect | Obvious effective rate (number) | Effective percentage (number) | Inefficiency (number) |
| Embodiment 1 | 44%(22) | 54%(27) | 2%(1) |
| Embodiment 2 | 42%(21) | 56%(28) | 2%(1) |
| Embodiment 3 | 42%(21) | 56%(28) | 2%(1) |
Embodiment contrast groups A
Comparative example 4,5,6 is added without the nutrition such as new fresh Herba Dendrobii, Fructus Vitis viniferae, Mel, water soluble dietary fiber and Oleum Vitis viniferae and becomes
Point, according to the raw material that the Chinese medicine part of embodiment 1,2,3 above is original, preparation for processing is traditional side of boiling
Method；The investigation method of using method and using effect is with above.
Table 2 embodiment contrast groups A drinks effect research
| Group/effect | Obvious effective rate (number) | Effective percentage (number) | Inefficiency (number) |
| Comparative example 4 | 36%(18) | 40%(20) | 24%(12) |
| Comparative example 5 | 40%(20) | 40%(20) | 20%(10) |
| Comparative example 6 | 46%(23) | 34%(17) | 20%(10) |
Embodiment contrast groups B
Comparative example 7,8,9 is added without the nutrition such as new fresh Herba Dendrobii, Fructus Vitis viniferae, Mel, water soluble dietary fiber and Oleum Vitis viniferae and becomes
Point, according to the raw material that the Chinese medicine part of embodiment 1,2,3 above is original, preparation for processing uses in embodiment 1
The preparation processing method of step E；The investigation method of using method and using effect is with above.
Table 3 embodiment contrast groups B drinks effect research
| Group/effect | Obvious effective rate (number) | Effective percentage (number) | Inefficiency (number) |
| Comparative example 7 | 32%(16) | 56%(28) | 12%(6) |
| Comparative example 8 | 28%(14) | 52%(31) | 10%(5) |
| Comparative example 9 | 36%(18) | 52%(26) | 12%(6) |
Embodiment contrast groups C
The processing method of comparative example 10,11,12 respectively corresponding embodiment 1,2,3 and formula, different be formula in
Without Air Bladder pseudosciaenae seu Acipenser composition；The investigation method of using method and using effect is with above.
Table 4 embodiment contrast groups C drinks effect research
| Group/effect | Obvious effective rate (number) | Effective percentage (number) | Inefficiency (number) |
| Comparative example 10 | 44%(22) | 46%(23) | 10%(5) |
| Comparative example 11 | 38%(19) | 50%(25) | 12%(6) |
| Comparative example 12 | 40%(20) | 48%(24) | 12%(6) |
Conclusion:
Contrasted by table 2 and table 1 and can be seen that
The inefficient number of embodiment contrast groups A is about 10 times of embodiment 1,2,3；This shows Chinese crude drug formula of the present invention
And between the nutritional labeling such as water soluble dietary fiber and Oleum Vitis viniferae, creating the most collaborative pharmacological action, aqueous soluble dietary is fine
Dimension increases effect of the wriggling of the intestines and stomach and promotes the human body absorption to ingredient, it is ensured that metabolic waste normally excretes, additionally
The anthocyanidin that contains in Pericarpium Vitis viniferae, resveratrol, have strong anti-oxidation, mutation, alleviate hepatosis, protection cardiovascular etc.
Function, strengthens immune system ability；Associate with Chinese medicine and improve assimilation effect and improve the mouthfeel of Chinese medicine, through the essence of the present invention simultaneously
The extraction of heart configuration and at utmost ingredient, Chinese crude drug formula of the present invention and preparation method occur in that beat all technology
Effect.
Table 2 and table 3 contrast can be seen that
About inefficient number is embodiment contrast groups B 2 times of embodiment contrast groups A, embodiment contrast groups B and traditional
Embodiment contrast groups A of boiling method has compared significant raising at therapeutic effect, and this shows that Chinese crude drug of the present invention is through step
The preparation processing method of rapid E has had significant raising than traditional boiling method, the extraction degree of active ingredient.
Table 1 is compared with table 4:
The formula of embodiment contrast groups C does not contains Air Bladder pseudosciaenae seu Acipenser, and the invalid number of embodiment contrast groups C is 5 times of left sides of embodiment 1,2,3
Right；And effective percentage number has and has declined；Show Air Bladder pseudosciaenae seu Acipenser serve in formula collaborative and priming return through effect, Air Bladder pseudosciaenae seu Acipenser should
Unexpected technique effect is achieved by effect.
In sum, a kind of blood-activating analgetic treatment gastric ulcer medicated tea that the present invention provides, blood-activating analgetic, blood circulation promoting and blood stasis dispelling, system
Acid pain relieving, treats gastric ulcer medicine, has sour-sweet mouthfeel, improves body immunity, defying age, eliminating toxin and beautifying the skin, nourishing taste, fall
Three-hypers, to prevent and treat diabetes and anti-cancer, the aspect such as anticancer the most powerful.And all raw materials is all from medicine-food two-purpose natural plants, nothing
Toxic and side effects.
The above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art
For Yuan, under the premise without departing from the principles of the invention, it is also possible to make some improvements and modifications, these improvements and modifications also should
It is considered as protection scope of the present invention.
Claims (7)
1. a blood-activating analgetic treatment gastric ulcer medicated tea, it is characterised in that be made up of the raw material of following weight portion: Rhizoma Coptidis 5-15
Part, Rhizoma Pinelliae 5-15 part, Radix Paeoniae Rubra 5-12 part, Radix Paeoniae Alba 3-9 part, Os Sepiae 5-12 part, Bulbus Fritillariae Uninbracteatae 5-10 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 10-16 part, Rhizoma Corydalis 5-
15 parts, Concha Arcae 6-15 part, Radix Aucklandiae 5-10 part, Pericarpium Citri Reticulatae 5-10 part, Radix Et Rhizoma Rhei 5-10 part, Rhizoma Zingiberis Recens 5-10 part, Fructus Aurantii Immaturus 5-10 part, Radix Bupleuri
5-10 part, Air Bladder pseudosciaenae seu Acipenser 5-10 part, new fresh Herba Dendrobii 10-20 part, Fructus Vitis viniferae 10-20 part, Mel, water are appropriate.
A kind of blood-activating analgetic treatment gastric ulcer medicated tea the most according to claim 1, it is characterised in that by following weight portion
Raw material is made: Rhizoma Coptidis 10 parts, the Rhizoma Pinelliae 10 parts, Radix Paeoniae Rubra 10 parts, the Radix Paeoniae Alba 8 parts, Os Sepiae 10 parts, Bulbus Fritillariae Uninbracteatae 8 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 12 parts, Rhizoma Corydalis
12 parts, Concha Arcae 12 parts, the Radix Aucklandiae 8 parts, Pericarpium Citri Reticulatae 8 parts, Radix Et Rhizoma Rhei 8 parts, 8 parts of Rhizoma Zingiberis Recens, Fructus Aurantii Immaturus 10 parts, Radix Bupleuri 8 parts, 8 parts of Air Bladder pseudosciaenae seu Acipenser, fresh
Herba Dendrobii 15 parts, Fructus Vitis viniferae 15 parts, Mel, water are appropriate.
A kind of blood-activating analgetic treatment gastric ulcer medicated tea the most according to claim 1, it is characterised in that by following weight portion
Raw material is made: Rhizoma Coptidis 5 parts, the Rhizoma Pinelliae 5 parts, Radix Paeoniae Rubra 5 parts, the Radix Paeoniae Alba 3 parts, Os Sepiae 5 parts, Bulbus Fritillariae Uninbracteatae 5 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10 parts, Rhizoma Corydalis 5 parts,
Concha Arcae 6 parts, the Radix Aucklandiae 5 parts, Pericarpium Citri Reticulatae 5 parts, Radix Et Rhizoma Rhei 5 parts, 5 parts of Rhizoma Zingiberis Recens, Fructus Aurantii Immaturus 5 parts, Radix Bupleuri 5 parts, 5 parts of Air Bladder pseudosciaenae seu Acipenser, new fresh Herba Dendrobii 10
Part, Fructus Vitis viniferae 10 parts, Mel, water are appropriate.
A kind of blood-activating analgetic treatment gastric ulcer medicated tea the most according to claim 1, it is characterised in that by following weight portion
Raw material is made: Rhizoma Coptidis 15 parts, the Rhizoma Pinelliae 15 parts, Radix Paeoniae Rubra 12 parts, the Radix Paeoniae Alba 9 parts, Os Sepiae 12 parts, Bulbus Fritillariae Uninbracteatae 10 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 16 parts, Rhizoma Corydalis
15 parts, Concha Arcae 15 parts, the Radix Aucklandiae 10 parts, Pericarpium Citri Reticulatae 10 parts, Radix Et Rhizoma Rhei 10 parts, 10 parts of Rhizoma Zingiberis Recens, Fructus Aurantii Immaturus 10 parts, Radix Bupleuri 10 parts, Air Bladder pseudosciaenae seu Acipenser 10
Part, new fresh Herba Dendrobii 20 parts, Fructus Vitis viniferae 20 parts, Mel, water are appropriate.
5. the preparation processing method of a blood-activating analgetic treatment gastric ulcer medicated tea, it is characterised in that comprise the following steps；
A, fresh for Herba Dendrobii bar is put into service sink, remove surface clay stain, the fresh bar of screening high-quality Herba Dendrobii, dry standby；
B, fresh for the Herba Dendrobii cleaned up bar is put into microwave oven, keep temperature 50-60 DEG C, carry out heating 10 minutes, then take
Go out to put into rotating centrifugal juice extractor, carry out three times and squeeze the juice, add the alcohol content of Herba Dendrobii fresh bar weight 0.1-0.5 times for the first time
The Chinese liquor of 52-60 DEG C, time 10-15min, the rotating speed of juice extractor is 20～30r/s；After standing 10 minutes, add the fresh bar of Herba Dendrobii
The distilled water of weight 2-3 times, for the second time juice extractor time 10-15min, juice extractor rotating speed is 80～100r/s, stands 10min；
After carry out third time squeeze the juice, add Herba Dendrobii fresh bar weight 3-5 times distilled water, time 20-30min, juice extractor rotating speed be 100～
150r/s, separates fresh for Herba Dendrobii bar juice with fiber filter, makes the fiber separation rate of the fresh bar of Herba Dendrobii reach more than 95%, cell damage
Rate reaches more than 80%, obtains new fresh Herba Dendrobii juice and Herba Dendrobii fresh bar fiber；The warm water that new fresh grape is put into 50-60 DEG C again cleans dry
After Jing, Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae are separated stand-by；
C, Herba Dendrobii fresh bar juice is put into and is put in pressure pan with Fructus Vitis viniferae meat, keeps pressure 0.5MP, temperature to keep 100-150 in tank
Degree, carries out infusion 10 minutes, obtains Matrix Solution I standby；
D, fresh for the Herba Dendrobii of separation bar fiber and Pericarpium Vitis viniferae are put into unglazed hermetically sealed can, in hermetically sealed can, add that to be equivalent to Herba Dendrobii fresh
Bar fiber and the Mel of Pericarpium Vitis viniferae gross weight 20-30% and the distilled water of 5-10 times of weight, stirring is smashed to 100 mesh, at 30-35
Seal at a temperature of DEG C and preserve 24h, sterilizing, filter, put into unglazed hermetically sealed can, obtain Matrix Solution standby；After extracting Matrix Solution
It is the cellulase of 0.5-0.7% that Pericarpium Vitis viniferae and Herba Dendrobii fresh bar fiber add mass volume ratio, adds the water of the mass ratio of 1:10,
Keep 35 DEG C, water soluble dietary fiber can be extracted further after 24h enzymolysis, water soluble dietary fiber is added Matrix Solution
Obtain Matrix Solution II；
E, take mix homogeneously after Radix Et Rhizoma Rhei, Rhizoma Zingiberis Recens cleaning and sterilizing, respectively with 6 times of weight 85% mol ratio ethanol extractions 2 times, each 2
Hour, merge 2 Radix Et Rhizoma Rhei, Rhizoma Zingiberis Recens ethanol extracts, receive alcohol and to be evaporated to relative density at 40 DEG C be 1.15-1.35, system
The extract obtaining Radix Et Rhizoma Rhei is standby；
Os Sepiae, Concha Arcae, Radix Aucklandiae mix and blend are put into super micron mill, and super micron mill heating keeps 120 degree of 5-6 of temperature
Minute, carry out micronizing and obtain the ultra micro mixing fine powders of 300-400 mesh；
Taking Rhizoma Coptidis, the Rhizoma Pinelliae, Radix Paeoniae Rubra, the Radix Paeoniae Alba, Bulbus Fritillariae Uninbracteatae, the Pseudobulbus Bletillae (Rhizoma Bletillae), Rhizoma Corydalis, Pericarpium Citri Reticulatae, Fructus Aurantii Immaturus, Radix Bupleuri, Air Bladder pseudosciaenae seu Acipenser, mix homogeneously adds 30-60
DEG C warm water soaking, after 10 minutes, puts into reach in freezer ,-10～-20 DEG C freezing 10-20 minute, forms freezing medicine block, by freezing
Medicine block and ultra micro mixing fine powders boiling are extracted 3 times, add 1-2 times amount water for the first time, and temperature keeps 100-120 DEG C, endures
Boil 10-20 minute；Second time adds 4-6 times amount water, and temperature keeps 80-100 DEG C, carries out infusion 10 minutes；Third time adds 6-10 times
Amount water, temperature keeps 120-150 DEG C, carries out infusion 30 minutes, filters, and is concentrated into the 1/2 of original volume, adds Radix Et Rhizoma Rhei, Rhizoma Zingiberis Recens
Extract, obtain Matrix Solution III standby；
F, take Matrix Solution I through instantaneous high-temperature 110-130 DEG C, 1-2 minute, put into material-compound tank；Take Matrix Solution II through mesh
Number be 100 mesh fine filter filter after put into material-compound tank；Take Matrix Solution III again to put into after the fine filter filter that mesh number is 60 mesh
In material-compound tank；
G, by Semen Vitis viniferae through vacuum outgas, then use CO2 supercritical fluid extraction, the condition of CO2 supercritical fluid extraction is:
Extracting pressure 45MPa, extraction temperature 35-45 DEG C, extraction time 30min, isolated Oleum Vitis viniferae；
H, three kinds of Matrix Solutions are stirring evenly and then adding into Oleum Vitis viniferae at material-compound tank, seal through bottle capper and load in vial,
Packaged vial puts into temperature 100～120 DEG C, 1.5MP, sterilization in 15～21 minutes steam ovens, packaging, vanning.
The preparation processing method of a kind of blood-activating analgetic the most according to claim 5 treatment gastric ulcer medicated tea, it is characterised in that
Step B) in, after new fresh grape cleans up, put into reach in freezer ,-10～-20 DEG C freezing 5-10 minute, make Fructus Vitis viniferae freeze,
After taking out nature defrosting, then carry out Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae detached job.
The preparation processing method of a kind of blood-activating analgetic the most according to claim 5 treatment gastric ulcer medicated tea, it is characterised in that
Step H) described in material-compound tank endobasal-body solution I, Matrix Solution II, Matrix Solution III, the weight proportion of Oleum Vitis viniferae be 10:
0.2～0.8:5～10:0.5.
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|---|---|---|---|---|
| CN111053815A (en) * | 2020-01-16 | 2020-04-24 | 广州同康药业有限公司 | A kind of traditional Chinese medicine composition for preventing acute gastric ulcer and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103300450A (en) * | 2013-06-14 | 2013-09-18 | 浙江大学 | Preparation method of raw dendrobium officinale pulp beverage |
-
2016
- 2016-04-17 CN CN201610234309.6A patent/CN106166279A/en active Pending
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103300450A (en) * | 2013-06-14 | 2013-09-18 | 浙江大学 | Preparation method of raw dendrobium officinale pulp beverage |
Non-Patent Citations (2)
| Title |
|---|
| 宋芳等: "超临界二氧化碳萃取葡萄籽油及其脂肪酸的分析", 《中国食品工业》 * |
| 李文亮等: "《千家妙方（上册）》", 31 May 1999, 战士出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111053815A (en) * | 2020-01-16 | 2020-04-24 | 广州同康药业有限公司 | A kind of traditional Chinese medicine composition for preventing acute gastric ulcer and preparation method thereof |
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