CN1061142C - 一种基于微粒光散射的免疫分析方法 - Google Patents

一种基于微粒光散射的免疫分析方法 Download PDF

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Publication number
CN1061142C
CN1061142C CN93119931A CN93119931A CN1061142C CN 1061142 C CN1061142 C CN 1061142C CN 93119931 A CN93119931 A CN 93119931A CN 93119931 A CN93119931 A CN 93119931A CN 1061142 C CN1061142 C CN 1061142C
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China
Prior art keywords
microsphere
analyte
potpourri
dimension
light scattering
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Expired - Fee Related
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CN93119931A
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English (en)
Chinese (zh)
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CN1092866A (zh
Inventor
W·P·汉森
M·仙纳拉佐
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Sienna Biotech Inc
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Sienna Biotech Inc
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/553Metal or metal coated
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02Investigating particle size or size distribution
    • G01N15/0205Investigating particle size or size distribution by optical means

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CN93119931A 1992-12-22 1993-12-21 一种基于微粒光散射的免疫分析方法 Expired - Fee Related CN1061142C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US99490392A 1992-12-22 1992-12-22
US994,903 1992-12-22

Publications (2)

Publication Number Publication Date
CN1092866A CN1092866A (zh) 1994-09-28
CN1061142C true CN1061142C (zh) 2001-01-24

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CN93119931A Expired - Fee Related CN1061142C (zh) 1992-12-22 1993-12-21 一种基于微粒光散射的免疫分析方法

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US (1) US5589401A (US20060003336A1-20060105-C00008.png)
EP (1) EP0676045A4 (US20060003336A1-20060105-C00008.png)
JP (1) JPH08505231A (US20060003336A1-20060105-C00008.png)
KR (1) KR0171452B1 (US20060003336A1-20060105-C00008.png)
CN (1) CN1061142C (US20060003336A1-20060105-C00008.png)
AU (1) AU670489B2 (US20060003336A1-20060105-C00008.png)
CA (1) CA2151060A1 (US20060003336A1-20060105-C00008.png)
TW (1) TW239881B (US20060003336A1-20060105-C00008.png)
WO (1) WO1994015193A1 (US20060003336A1-20060105-C00008.png)

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FR2797690B1 (fr) * 1999-08-20 2001-10-12 Bio Merieux Procede de detection d'un analyte et necessaire pour la mise en oeuvre de ce procede
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US7781172B2 (en) 2003-11-21 2010-08-24 Kimberly-Clark Worldwide, Inc. Method for extending the dynamic detection range of assay devices
US7247500B2 (en) 2002-12-19 2007-07-24 Kimberly-Clark Worldwide, Inc. Reduction of the hook effect in membrane-based assay devices
US20040197819A1 (en) 2003-04-03 2004-10-07 Kimberly-Clark Worldwide, Inc. Assay devices that utilize hollow particles
US7851209B2 (en) 2003-04-03 2010-12-14 Kimberly-Clark Worldwide, Inc. Reduction of the hook effect in assay devices
US20050112703A1 (en) 2003-11-21 2005-05-26 Kimberly-Clark Worldwide, Inc. Membrane-based lateral flow assay devices that utilize phosphorescent detection
US7943395B2 (en) 2003-11-21 2011-05-17 Kimberly-Clark Worldwide, Inc. Extension of the dynamic detection range of assay devices
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JP4730304B2 (ja) * 2004-05-20 2011-07-20 和光純薬工業株式会社 ヒアルロン酸バインディングプロテインを用いたヒアルロン酸の測定方法
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CN110998294A (zh) * 2017-08-10 2020-04-10 Jvc建伍株式会社 分析方法和分析装置
CN111398577A (zh) * 2020-06-08 2020-07-10 南京颐兰贝生物科技有限责任公司 一种定量免疫检测方法
EP4409288A1 (en) * 2021-10-01 2024-08-07 PNP Research LLC Optical background suppression in binding assays that employ polymeric microspheres

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Also Published As

Publication number Publication date
US5589401A (en) 1996-12-31
AU5873494A (en) 1994-07-19
EP0676045A1 (en) 1995-10-11
WO1994015193A1 (en) 1994-07-07
KR0171452B1 (ko) 1999-05-01
CA2151060A1 (en) 1994-07-07
JPH08505231A (ja) 1996-06-04
AU670489B2 (en) 1996-07-18
CN1092866A (zh) 1994-09-28
EP0676045A4 (en) 1998-02-04
TW239881B (US20060003336A1-20060105-C00008.png) 1995-02-01

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