CN106109493A - One is exclusively used in hypo-allergenic combination medicament during planting tooth - Google Patents
One is exclusively used in hypo-allergenic combination medicament during planting tooth Download PDFInfo
- Publication number
- CN106109493A CN106109493A CN201610637578.7A CN201610637578A CN106109493A CN 106109493 A CN106109493 A CN 106109493A CN 201610637578 A CN201610637578 A CN 201610637578A CN 106109493 A CN106109493 A CN 106109493A
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- CN
- China
- Prior art keywords
- sodium
- combination medicament
- hypo
- exclusively used
- tooth
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/16—Fluorine compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/42—Phosphorus; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0063—Periodont
Abstract
The invention discloses belong to the one of oral cavity health preparation technical field be exclusively used in plant tooth during hypo-allergenic combination medicament.This combination medicament comprises the material for the treatment of hemodia, the reduction material of dentinal sensitivity pain, pH value regulator, stabilizer, flavour enhancer and deionized water；This combination medicament is directly applied to dental surface or uses dens supporter to be applied to dental surface, hemodia symptom and the pain caused by allergy can be alleviated immediately.
Description
Technical field
The invention belongs to oral cavity health preparation field, be exclusively used in hypo-allergenic combination medicine during planting tooth particularly to one
Agent, for preventing hemodia and alleviating the pain caused by allergy.
Background technology
Hemodia is primarily due to when enamel is destroyed, and when dentin exposes, various stimulations are in dentin table
Face, makes dentin flow velocity change, and this abnormal flow passes to dental pulp, causes nerve fiber excited and produces the pain sensation.Tooth
Tooth allergy is one of most common oral health issue, and it directly affects the quality of life of people.Although grinding of antagonism allergy toothpaste
System report is a lot, but most develop all antiallergic as the miscellaneous function of cleaning of teeth, and typically to use one section the longest
Time (more than 3 weeks) just can take effect, special anti-allergic agent is the most few, and research finds, fluoride by with the tooth of tooth this
Matter effect, can form one layer of hard fluor-apatite at dental surface, thus improve adamantine hardness；Strontium chloride, nitric acid
Potassium can make the permeability of dental tissue significantly reduce, and reduces the Yin Yuan periodontal tissue sensitivity to various stimulations；Gel or colloid
Complex mechanicalness can close the mouth of pipe matching dential canaliculi, can play anti-allergic effects at short notice.But, in the market
The product that the combination of these several respects is used for dental sensitivity treatment is not also had been reported that.
Summary of the invention
Instant invention overcomes the deficiencies in the prior art, it is provided that one is exclusively used in hypo-allergenic combination medicament during planting tooth, should
The using method of compositions is to be directly applied to the dental surface after planting tooth or use dens supporter to be applied to dental surface, can be immediately
Alleviate hemodia symptom and the pain caused by allergy.
For solving above-mentioned technical problem, the present invention by the following technical solutions:
One is exclusively used in hypo-allergenic combination medicament during planting tooth, and it includes, it is characterised in that: described combination medicament comprises treatment
The material of hemodia, the reduction material of dentinal sensitivity pain, pH value regulator, stabilizer and deionized water;Described each group
The percentage by weight divided is as follows:
The material 3%-5% for the treatment of hemodia
Reduce the material 0.1%-0.2% of dentinal sensitivity pain
PH value regulator 0.1%-2%
Stabilizer 1%-2%
Deionized water 90.8%-95.8%
The material of described treatment hemodia is one or more in sodium fluoride, potassium fluoride, sodium monofluorophosphate；Described reduction tooth
The material of tooth hyperalgesia is strontium chloride and/or potassium nitrate；Described pH value regulator is sodium hydroxide, potassium hydroxide, carbonic acid
One or more in sodium, sodium bicarbonate, triethanolamine；Described stabilizer is sodium pyrophosphate, sodium dihydrogen phosphate, EDTA, EDTA
One or more in disodium, EDETATE SODIUM calcium, 1-hydroxy ethylidene-1,1-diphosphonic acid.
Further, the material of described treatment hemodia is sodium fluoride.
Further, the material of described reduction dentinal sensitivity pain is strontium chloride.
Further, described pH value regulator is sodium hydroxide.
Further, described stabilizer is sodium pyrophosphate.
Compared with prior art, the invention has the beneficial effects as follows: the tooth antiallergic composition that the present invention provides can stand
I.e. alleviate hemodia symptom and the pain caused by allergy.Tested patient was with latter 10 seconds, and effective percentage can reach 80%
More than and.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated.Embodiments of the present invention include but not limited to following
Embodiment.
Following non-limiting example is further discussed below the preferred embodiment in the scope of the invention.Without departing substantially from the present invention
In the case of scope, a lot of changes of the present embodiment are possible.
Embodiment 1
Weight percentages of components (%)
Sodium fluoride 5%
Strontium chloride 0.2%
Sodium hydroxide 2%
Sodium pyrophosphate 2%
Deionized water 90.8%
Preparation method: then other material beyond dehydrogenation sodium oxide is added in deionized water and dissolve, be eventually adding hydroxide
Sodium stirs and i.e. obtains tooth antiallergic composition.
Embodiment 2
Weight percentages of components (%)
Sodium fluoride 3%
Strontium chloride 0.1%
Sodium hydroxide 0.1%
Sodium pyrophosphate 1%
Deionized water 95.8%
Preparation method: then other material beyond dehydrogenation sodium oxide is added in deionized water and dissolve, be eventually adding hydroxide
Sodium stirs and i.e. obtains tooth antiallergic composition.
Embodiment 2
Weight percentages of components (%)
Sodium fluoride 4%
Strontium chloride 0.15%
Sodium hydroxide 1%
Sodium pyrophosphate 1.5%
Deionized water 93.35%
Preparation method: then other material beyond dehydrogenation sodium oxide is added in deionized water and dissolve, be eventually adding hydroxide
Sodium stirs and i.e. obtains tooth antiallergic composition.
The patient of 60 easy allergy of tooth is divided into four groups, to three kinds of tooth antiallergic combinations in embodiment 1-3
Thing and at present elimination hemodia symptom conventional use of antiallergic toothpaste are tested.Each group patient is accepting various stimulations
After, use above-mentioned three kinds of compositionss and toothpaste respectively, observe each patient and use rear reaction.From test result, the group of the present invention
Compound can quickly eliminate hemodia symptom, and uses toothpaste to need just can take effect for more than 3 weeks.It is the present invention's as mentioned above
Embodiment.The present invention is not limited to above-mentioned embodiment, and anyone should learn that the structure made under the enlightenment of the present invention becomes
Changing, every have same or like technical scheme, within each falling within protection scope of the present invention with the present invention.
Claims (5)
1. being exclusively used in a hypo-allergenic combination medicament during planting tooth, it includes, it is characterised in that: described combination medicament comprises to be controlled
Treat the material of hemodia, reduce the material of dentinal sensitivity pain, pH value regulator, stabilizer and deionized water;Described respectively
The percentage by weight of component is as follows:
The material 3%-5% for the treatment of hemodia
Reduce the material 0.1%-0.2% of dentinal sensitivity pain
PH value regulator 0.1%-2%
Stabilizer 1%-2%
Deionized water 90.8%-95.8%
The material of described treatment hemodia is one or more in sodium fluoride, potassium fluoride, sodium monofluorophosphate；Described reduction tooth
The material of tooth hyperalgesia is strontium chloride and/or potassium nitrate；Described pH value regulator is sodium hydroxide, potassium hydroxide, carbonic acid
One or more in sodium, sodium bicarbonate, triethanolamine；Described stabilizer is sodium pyrophosphate, sodium dihydrogen phosphate, EDTA, EDTA
One or more in disodium, EDETATE SODIUM calcium, 1-hydroxy ethylidene-1,1-diphosphonic acid.
One the most according to claim 1 is exclusively used in hypo-allergenic combination medicament during planting tooth, it is characterised in that control described in:
The material treating hemodia is sodium fluoride.
One the most according to claim 1 is exclusively used in hypo-allergenic combination medicament during planting tooth, it is characterised in that: described fall
The material of low dentinal sensitivity pain is strontium chloride.
One the most according to claim 1 is exclusively used in hypo-allergenic combination medicament during planting tooth, it is characterised in that: described
PH value regulator is sodium hydroxide.
One the most according to claim 1 is exclusively used in hypo-allergenic combination medicament during planting tooth, it is characterised in that: described surely
Determining agent is sodium pyrophosphate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610637578.7A CN106109493A (en) | 2016-08-05 | 2016-08-05 | One is exclusively used in hypo-allergenic combination medicament during planting tooth |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610637578.7A CN106109493A (en) | 2016-08-05 | 2016-08-05 | One is exclusively used in hypo-allergenic combination medicament during planting tooth |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106109493A true CN106109493A (en) | 2016-11-16 |
Family
ID=57254754
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610637578.7A Pending CN106109493A (en) | 2016-08-05 | 2016-08-05 | One is exclusively used in hypo-allergenic combination medicament during planting tooth |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106109493A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108653398A (en) * | 2018-07-18 | 2018-10-16 | 苏州工业园区方津口腔诊所有限公司 | One kind being exclusively used in hypo-allergenic combination medicament during plant tooth |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1688281A (en) * | 2002-08-05 | 2005-10-26 | 高露洁-棕榄公司 | Dentinal desensitizing toothpaste |
| CN101507689A (en) * | 2009-04-02 | 2009-08-19 | 南昌普洋科技有限公司 | Gel for bleaching and whitening teeth |
| CN101829329A (en) * | 2010-05-11 | 2010-09-15 | 李少君 | Tooth antiallergic composition |
-
2016
- 2016-08-05 CN CN201610637578.7A patent/CN106109493A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1688281A (en) * | 2002-08-05 | 2005-10-26 | 高露洁-棕榄公司 | Dentinal desensitizing toothpaste |
| CN101507689A (en) * | 2009-04-02 | 2009-08-19 | 南昌普洋科技有限公司 | Gel for bleaching and whitening teeth |
| CN101829329A (en) * | 2010-05-11 | 2010-09-15 | 李少君 | Tooth antiallergic composition |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108653398A (en) * | 2018-07-18 | 2018-10-16 | 苏州工业园区方津口腔诊所有限公司 | One kind being exclusively used in hypo-allergenic combination medicament during plant tooth |
| CN108653398B (en) * | 2018-07-18 | 2021-06-04 | 苏州工业园区方津口腔诊所有限公司 | Anti-allergy combined medicament special for tooth implantation process |
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| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20161116 |
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| RJ01 | Rejection of invention patent application after publication |