CN106085877A - A kind of mycelium combined by Fructus Jujubae, Fructus Lycii, Cordyceps - Google Patents

A kind of mycelium combined by Fructus Jujubae, Fructus Lycii, Cordyceps Download PDF

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CN106085877A
CN106085877A CN201610479820.2A CN201610479820A CN106085877A CN 106085877 A CN106085877 A CN 106085877A CN 201610479820 A CN201610479820 A CN 201610479820A CN 106085877 A CN106085877 A CN 106085877A
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cordyceps
fructus
fructus lycii
mycelium
fructus jujubae
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黄秀英
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    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/062Ascomycota
    • A61K36/066Clavicipitaceae
    • A61K36/068Cordyceps

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Abstract

A kind of mycelium combined by Fructus Jujubae, Fructus Lycii, Cordyceps, it is to be that primary raw material is as culture medium with Fructus Jujubae, Fructus Lycii, cordyceps species will be accessed after medium sterilization, then cultivate and cover with culture medium to mycelia and obtain Fructus Jujubae, Fructus Lycii, Cordyceps combination mycelia block, finally mycelia block is ground into mycelium after shining or drying.By implementing the present invention, by biotechnology, Fructus Jujubae, Fructus Lycii, Cordyceps composition are formed the Fructus Jujubae of novel characteristic, Fructus Lycii, Cordyceps combination mycelium, the formation of product not only has characteristic, novelty, and makes its nutrition more be enriched with, and its function and health-care effect are more prominent.It is the health product of a kind of novel characteristic.Meanwhile, Fructus Jujubae, Fructus Lycii, the process for producing of Cordyceps combination mycelia block have the features such as cultivation period is short, process for producing simple, the production efficiency of product is high and stablizes.

Description

A kind of mycelium combined by Fructus Jujubae, Fructus Lycii, Cordyceps
Technical field
The invention belongs to biological technical field, be specifically related to a kind of mycelia combined by Fructus Jujubae, Fructus Lycii, Cordyceps Body.
Background technology
Described Cordyceps, is also Cordyceps militaris, is a kind of rich in cordycepin, high protein, amino acid whose edible fungi, is first-class Excellent tonic product.Current tame Cordyceps militaris mainly has two classes: a class is that artificial breeding forms with the raw bacterium of worm pupa, and second Class is modal on market, and artificial breeding forms with frumentum, the Semen Tritici aestivi raw bacterium of fermentation.
Cordyceps militaris (L.) Link. grass length 5~8 centimeters, golden yellow, orange colour, belong to Eumycota Cordyceps with Cordyceps of Qinghai Province, There is similar medicinal and nourishing effects.Thinking the Research on kinds having become as induction Cordyceps sporophore both at home and abroad, Cordyceps militaris is eaten Can match in excellence or beauty with traditional Cordyceps with medical value, the Cordyceps militaris cordycepin content of artificial culture is higher than tradition Cordyceps Tens times.
Modern medicine and pharmacology research proves, Cordyceps militaris (L.) Link. contains rich in protein, 18 kinds of aminoacid, 17 kinds of trace units Element, 12 kinds of vitamin: A, B1, B2, B6, B12, C, D, E equal size is higher than mushrooms, has nourishing the lung and kidney, hemostasis and phlegm, expansion The effect such as trachea, calmness, anti-each bacterioid, blood pressure lowering.Through Hong Kong, Korea S, Japan, Canada, the U.S. and domestic state more than ten Research and the detection of the countries in the world such as individual unit prove, Cordyceps militaris is the Ideal Substitute of tradition Cordyceps.
Cordyceps militaris is prepared as tea beverage, tool defying age, resisting fatigue, anticancer, antiinflammatory, antibacterial, protect the heart, protect the liver, lung moistening, benefit The multiple medical care effects such as kidney and enhancing body, U.S. face black hair.Also general nutritional health food it is different from only to nutrient in a certain respect Deficiency carry out supplementing and strengthening, but on the whole two-ways regulation function of human body balance, transfer internal body vigor, regulate people Body metabolism function, improves autoimmune ability, promotes whole internal organs or organ function normalization.
Along with technical research constantly deeply, brand-new Cordyceps militaris product is obtained by biological submerged fermentation technology Scarlet caterpiller fungus mycelia.Detect through relevant departments: scarlet caterpiller fungus mycelia has the effective ingredient that Cordyceps militaris is identical, wherein crude polysaccharides And the content of Cordyceps militaris polysaccharide and protein is significantly larger than natural Cordyceps militaris.Cordyceps militaris bacterium is produced by biological submerged fermentation technology Filament, the features such as it is with short production cycle, technique is simple, production efficiency is high, stable, are that the main of artificial culture Cordyceps militaris product is sent out Exhibition direction.The by-product of the current raw material main food produced used by scarlet caterpiller fungus mycelia or plant amylum, rice meal, Semen Maydis Powder, analysis for soybean powder etc., and to add a little mineral element on the basis of above-mentioned raw materials be carbon and nitrogen sources, mycelium passes through after cultivating again Dry and be ground into powder.Mycelium can have been run off by its nutritional labeling after drying.Additionally produce by such technique In addition to function that mycelium product out has except product itself, effect, the poor morphology of its product formation, mouthfeel are the best, very To without any taste, it is impossible to attract much attention, so product promotion poor effect.
Summary of the invention
The purpose of the present invention be exactly overcome the deficiency of above-mentioned technology and provide brand-new by Fructus Jujubae, Fructus Lycii, Cordyceps combination and A kind of mycelium become.Specifically include: this mycelium be with Fructus Jujubae, Fructus Lycii be primary raw material as culture medium, culture medium is gone out Access cordyceps species after bacterium, then cultivate and cover with culture medium to mycelia and obtain Fructus Jujubae, Fructus Lycii, Cordyceps combination mycelia block, finally Mycelia block is ground into mycelium after shining or drying.
Described Fructus Jujubae, has another name called Fructus Jujubae.Feature is that vitamin content is the highest, has the good reputation of " natural complex ball ", tool There is nourishing YIN and invigorating YANG, the effect enriched blood.Fructus Jujubae is a kind of nutrient excellent product, is described as " king of BAIGUO ".It is raw that Fructus Jujubae contains abundant dimension The necessary multivitamin of human body and 18 kinds of aminoacid, mineral such as element A, B, C, the wherein content of vitamin C (ascorbic acid) Unexpectedly be up to Fructus Vitis viniferae, 70~80 times of Fructus Mali pumilae, the content of rutin (Citrin) is the highest, both vitamin to anti-cancer and prevention Hypertension, hyperlipidemia have certain effect.Fructus Jujubae sweet in the mouth warm in nature, containing protein, fat, sugar, calcium, phosphorus, ferrum, magnesium and abundant Vitamin A, vitamin C, vitamin B1, vitamin B2, additionally contain carotene etc., and nutrition is the abundantest, among the people have " my god It eats Fructus Jujubae, and all one's life bears one's age well " say.The fruit that people like is not only by Fructus Jujubae, be also simply nourishing spleen and stomach, nourishing blood to tranquillize the mind, The good medicine promoted health and cured diseases.Puerpera eats Fructus Jujubae, energy invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind, accelerates body and restores;Oldaged physically weak person eats Fructus Jujubae, energy health invigorating, slow down aging;The people being more especially engaged in mental work and neurastheniac, boil soup generation with Fructus Jujubae Tea, can feel at ease to keep god, appetite stimulator.Have the people of tea addiction, cross drink night, toss about in bed sleeplessness unavoidably, if decocting soup generation with Fructus Jujubae every night Tea, can exempt the hardship of insomnia.In season in spring and autumn, first tremble with fear and first warm up, Fructus Jujubae adds several Folium Mori and decocts Tang Daicha, cold sense can be prevented Emit;Summertime is hot, and Fructus Jujubae and Folium Nelumbinis are with boiling and can relieve summer heat by promoting the circulation of QI;Severe cold of winter, Fructus Jujubae Tonga fresh ginger brown sugar, warming the stomach of can dispeling cold.Red Fructus Jujubae is natural beauty food, also can replenishing QI to invigorate the spleen, promote QI and blood biochemistry circulation and defying age.Fructus Jujubae is not only a kind of deep by old The food that the common people like, is also the Chinese medicine commonly used simply.Modern pharmacological research finds, containing more protein, ammonia in Fructus Jujubae Base acid, saccharide, organic acid, vitamin A, vitamin B2. vitamin C, P etc., and microelements of calcium, phosphorus, potassium, ferrum, magnesium, Aluminum and substantial amounts of cyclic adenosine monophosphate etc..Its warm in nature, sweet in the mouth, has invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind, born fluid, solution poison of drug, obtundent Effect of property.The method that " the nourishing the liver soup " of the traditional Chinese medical science the most useful Fructus Jujubae prescription carrys out liver-nourishing, toxin-expelling.Hubei Provincial Hospital of TCM state of internal organs liver Sick director of the Institute doctoral advisor professor Sheng Guoguang introduces, Fructus Jujubae have protect the liver, spleen invigorating, reduction cholesterol, raise leukocyte, Antiallergic etc. act on.
Described Fructus Lycii is that people are to the system of species under the Lyciums such as commodity Fructus Lycii, plant lycium barbarum, China Fructus Lycii Claim (Chinese medicine claims Fructus Lycii).With fine jade treasure Ganoderma, Changbai Mountain Radix Ginseng, Donga Colla Corii Asini referred to as Chinese medicine four are precious.The Main Ingredients and Appearance of Fructus Lycii: Lycium barbarum polysaccharide, Fructus Lycii contain glycine betaine (betane), atropine (atropine), hyoscyamine (gyoscyamine), Fructus Lycii color Element etc..Wherein, lycium barbarum polysaccharide is a kind of water soluble polysaccharide, is topmost active component in Fructus Lycii, and relative molecular mass is 68- 200, become domestic and international study hotspot.The most again with immunomodulating and the most study of antitumor action of lycium barbarum polysaccharide.? Lycium barbarum polysaccharide has promotion immunity, defying age, antitumor, removing free radical, resisting fatigue, radioprotective, guarantor to have a lot of research to show The effects such as liver, reproductive function protection and improvement.Glycine betaine, chemical name is 1-carboxy-N, N, N-betaine, is changing With amino acid similarity in structure, belong to quaternary amine alkaloids.Glycine betaine is one of alkaloid main in FRUCTUS LYCII, leaf, handle. Lipid metabolism or lipotropic effect are caused by Fructus Lycii mainly due to contained glycine betaine, and it plays methyl supply in vivo The effect of body.Research about Fructus Lycii glycine betaine is only limitted to the domestic mensuration at content, extraction process and the life to lycium plant Reason effect (enhancing salt tolerance) research aspect, the pharmacological effect about Fructus Lycii glycine betaine is studied seldom.Wolfberry pigment is present in All kinds of present-color materials in Fructus Lycii berry, are the important physiologically active ingredients of seed of Fructus Lycii.Mainly include-carotene, phylloxanthin and Other coloring matters.Carotenoid contained by Fructus Lycii then has very important medical value.A lot of researchs have turned out Chinese holly Qi seed pigment has raising immune function of human body, prevent and suppress tumor and prevention of arterial is atherosis etc. acts on.Carotene is The main active of wolfberry pigment, has antioxidation and the synthesis important physiological function such as precursor as vitamin A.
The present invention is achieved through the following technical solutions:
A kind of mycelium combined by Fructus Jujubae, Fructus Lycii, Cordyceps, is in technical scheme: this mycelium is with Fructus Jujubae, Fructus Lycii For primary raw material as culture medium, by accessing cordyceps species after medium sterilization, then cultivate and cover with culture medium to mycelia and obtain To Fructus Jujubae, Fructus Lycii, Cordyceps combination mycelia block, finally mycelia block is ground into mycelium after shining or drying.
Specifically include following steps:
1, Fructus Jujubae collection and process: gather and parch, without rotten, the normal red date as raw materials of color and luster, then by extracting red date stone and break It is broken into as niblet size standby.
2, Fructus Lycii gathers and processes: collection parches, is raw material without rotten, the normal Fructus Lycii of color and luster.
3, preparation culture medium: culture medium is the rice meal group of the Fructus Jujubae by 48%, the Fructus Lycii of 40%, the Semen Maydis powder of 7% and 5% Becoming, first mix above-mentioned various raw materials stir to obtain compound, then admixes in compound with the brown sugar water of 3%, The moisture content of compound is adjusted to 55-60%, then mixed material is sub-packed in culture vessel, and charge weight is that mixed material exists Thickness in culture vessel is 2-3cm, the most conventionally must produce after sterilizing and use culture medium.
4, inoculation: access cordyceps species in an aseptic environment.
5, cultivation: the culture vessel connected kind is moved on to culturing room and carries out lucifuge cultivation, temperature be 20~23 DEG C, relatively Humidity is to cultivate in the environment of 60~65% to mycelia to cover with culture medium.
6, cultivate mycelia block: when Cordyceps mycelium covers with culture medium, continue to cultivate Fructus Jujubae and Chinese holly intertexture connection to mycelia Become mycelia block.
7, dry: through shining or drying to material moisture less than 8% in the environment of mycelia block is placed below 50 °.
8, finished product: the mycelia block through shining or dry is crushed to cross 100-120 mesh and obtains finished product mycelium.
The present invention both had the following advantages:
1, the proposed by the invention a kind of mycelium its preparation method combined by Fructus Jujubae, Fructus Lycii, Cordyceps is novel, raw Production. art is simply, easily implement.
2, by implementing the present invention, by biotechnology Fructus Jujubae, Fructus Lycii, the combination of Cordyceps combination another characteristic of formation Body Fructus Jujubae, Fructus Lycii, Cordyceps combination mycelium, the formation of product not only has characteristic, novelty, and makes its nutrition richer Collection, and its function and health-care effect are more prominent.It is the health product of a kind of novel characteristic.
3, by implementing the present invention, final products Fructus Jujubae, Fructus Lycii, Cordyceps combine mycelial process for producing tool There are the features such as cultivation period is short, process for producing simple, the production efficiency of product is high and stablizes.
4, by implementing the present invention, the product purpose of formation is extensive, can be as being prepared as medicine, health product, characteristic food The raw material of product additive.Also the health product obtaining a kind of characteristic can be loaded in capsule.Not only there is extraordinary market prospect, and The economic benefit produced also can highly significant.
Detailed description of the invention
Below in conjunction with embodiment, the method for the present invention is further illustrated.
A kind of mycelium combined by Fructus Jujubae, Fructus Lycii, Cordyceps, is in technical scheme: this mycelium be with Fructus Jujubae, Fructus Lycii is primary raw material as culture medium, will access cordyceps species after medium sterilization, then cultivates to mycelia and covers with culture medium And obtain Fructus Jujubae, Fructus Lycii, Cordyceps combination mycelia block, finally mycelia block is ground into mycelium after shining or drying.
Embodiment 1:
1, Fructus Jujubae collection and process: gather and parch, without rotten, the normal red date as raw materials of color and luster, then by extracting red date stone and break It is broken into as niblet size standby.
2, Fructus Lycii gathers and processes: collection parches, is raw material without rotten, the normal Fructus Lycii of color and luster.
3, preparation culture medium: culture medium is the rice meal group of the Fructus Jujubae by 48%, the Fructus Lycii of 40%, the Semen Maydis powder of 7% and 5% Becoming, first mix above-mentioned various raw materials stir to obtain compound, then admixes in compound with the brown sugar water of 3%, The moisture content of compound is adjusted to 55-60%, then mixed material is sub-packed in culture vessel, and charge weight is that mixed material exists Thickness in culture vessel is 2-3cm, the most conventionally must produce after sterilizing and use culture medium.
4, inoculation: access the cordyceps species of 7-8 point in an aseptic environment.
5, cultivation: the culture vessel connected kind is moved on to culturing room and carries out lucifuge cultivation, temperature be 20~23 DEG C, relatively Humidity is to cultivate in the environment of 60~65% to mycelia to cover with culture medium.
6, cultivate mycelia block: when Cordyceps mycelium covers with culture medium, continue to cultivate Fructus Jujubae and Chinese holly intertexture connection to mycelia Become mycelia block.
7, dry: through shining or drying to material moisture less than 8% in the environment of mycelia block is placed below 50 °.
8, finished product: the mycelia block through shining or dry is crushed to cross 100-120 mesh and obtains finished product mycelium.
9, commodity: mycelium is dispensed in capsule to obtain a kind of Fructus Jujubae, Fructus Lycii, Cordyceps combination mycelium capsule.
Embodiment 2:
1, Fructus Jujubae collection and process: gather and parch, without rotten, the normal red date as raw materials of color and luster, then by extracting red date stone and break It is broken into as niblet size standby.
2, Fructus Lycii gathers and processes: collection parches, is raw material without rotten, the normal Fructus Lycii of color and luster.
3, preparation culture medium: culture medium is the rice meal group of the Fructus Jujubae by 48%, the Fructus Lycii of 40%, the Semen Maydis powder of 7% and 5% Becoming, first mix above-mentioned various raw materials stir to obtain compound, then admixes in compound with the brown sugar water of 3%, The moisture content of compound is adjusted to 55-60%, then mixed material is sub-packed in culture vessel, and charge weight is that mixed material exists Thickness in culture vessel is 2-3cm, the most conventionally must produce after sterilizing and use culture medium.
4, inoculation: access 10~the cordyceps species of 12% according to the weight of culture medium in an aseptic environment.
5, cultivation: the culture vessel connected kind is moved on to culturing room and carries out lucifuge cultivation, temperature be 20~23 DEG C, relatively Humidity is to cultivate in the environment of 60~65% to mycelia to cover with culture medium.
6, cultivate mycelia block: when Cordyceps mycelium covers with culture medium, continue to cultivate Fructus Jujubae and Chinese holly intertexture connection to mycelia Become mycelia block.
7, dry: through shining or drying to material moisture less than 8% in the environment of mycelia block is placed below 50 °.
8, finished product: the mycelia block through shining or dry is crushed to cross 100-120 mesh and obtains finished product mycelium.
9, commodity: mycelium is dispensed in capsule to obtain a kind of Fructus Jujubae, Fructus Lycii, Cordyceps combination mycelium capsule.

Claims (1)

1. a kind of mycelium combined by Fructus Jujubae, Fructus Lycii, Cordyceps, it is characterised in that: this mycelium is to be with Fructus Jujubae, Fructus Lycii Primary raw material, as culture medium, by accessing cordyceps species after medium sterilization, is then cultivated and is covered with culture medium to mycelia and obtain Fructus Jujubae, Fructus Lycii, Cordyceps combination mycelia block, be finally ground into mycelium by mycelia block after shining or drying;
Specifically include following steps:
(1) Fructus Jujubae collection and process: gather and parch, without rotten, the normal red date as raw materials of color and luster, then by extracting red date stone and break It is broken into as niblet size standby;
(2) Fructus Lycii gathers and processes: collection parches, is raw material without rotten, the normal Fructus Lycii of color and luster;
(3) culture medium is prepared: culture medium is made up of the rice meal of Fructus Jujubae, the Fructus Lycii of 40%, the Semen Maydis powder of 7% and 5% of 48%, first Mix above-mentioned various raw materials stir to obtain compound, then admixes in compound with the brown sugar water of 3%, mixing The moisture content of material is adjusted to 55-60%, then mixed material is sub-packed in culture vessel, and charge weight is that mixed material is being cultivated Thickness in container is 2-3cm, the most conventionally must produce after sterilizing and use culture medium;
(4) inoculation: access cordyceps species in an aseptic environment;
(5) cultivation: the culture vessel connected kind is moved on to culturing room and carries out lucifuge cultivation, temperature be 20~23 DEG C, the wettest Degree is to cultivate in the environment of 60~65% to mycelia to cover with culture medium;
(6) cultivate mycelia block: when Cordyceps mycelium covers with culture medium, continue cultivation, to mycelia, Fructus Jujubae and Chinese holly intertexture are connected into bacterium Silk block;
(7) dry: through shining or drying to material moisture less than 8% in the environment of mycelia block is placed below 50 °;
(8) finished product: the mycelia block through shining or dry is crushed to cross 100-120 mesh and obtains finished product mycelium.
CN201610479820.2A 2016-06-28 2016-06-28 A kind of mycelium combined by Fructus Jujubae, Fructus Lycii, Cordyceps Pending CN106085877A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109550040A (en) * 2019-01-22 2019-04-02 广西壮仁堂生物科技有限公司 A kind of Chinese medicine peptide composition of strengthen immunity

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103820299A (en) * 2012-11-19 2014-05-28 水塔(北京)老陈醋生物科学有限公司 Worm grass mycelium fermented vinegar and preparation method thereof
CN104350942A (en) * 2014-10-21 2015-02-18 广西平果利华茧丝绸有限公司 Method for preparing cordyceps mycelia through mulberry twig powder and silkworm chrysalis powder

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103820299A (en) * 2012-11-19 2014-05-28 水塔(北京)老陈醋生物科学有限公司 Worm grass mycelium fermented vinegar and preparation method thereof
CN104350942A (en) * 2014-10-21 2015-02-18 广西平果利华茧丝绸有限公司 Method for preparing cordyceps mycelia through mulberry twig powder and silkworm chrysalis powder

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109550040A (en) * 2019-01-22 2019-04-02 广西壮仁堂生物科技有限公司 A kind of Chinese medicine peptide composition of strengthen immunity

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