CN106075315A - A kind of antianaphylactic Chinese medicine composition and preparation method thereof - Google Patents
A kind of antianaphylactic Chinese medicine composition and preparation method thereof Download PDFInfo
- Publication number
- CN106075315A CN106075315A CN201610688426.XA CN201610688426A CN106075315A CN 106075315 A CN106075315 A CN 106075315A CN 201610688426 A CN201610688426 A CN 201610688426A CN 106075315 A CN106075315 A CN 106075315A
- Authority
- CN
- China
- Prior art keywords
- parts
- chinese medicine
- medicine composition
- fructus
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/708—Rheum (rhubarb)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/58—Reptiles
- A61K35/583—Snakes; Lizards, e.g. chameleons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/238—Saposhnikovia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
- A61K36/744—Gardenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Abstract
The present invention relates to technical field of traditional Chinese medicine preparation, a kind of antianaphylactic Chinese medicine composition and preparation method thereof, is made up of the raw material of following portions by weight: Radix et Rhizoma Rhei (processed) 9～15 parts, Bombyx Batryticatus 9～15 parts, Periostracum Cicadae 9～15 parts, Zaocys 9～15 parts, Rhizoma Curcumae Longae 9～15 parts, Fructus Atriplicis Sibiricae 9～15 parts, Radix Saposhnikoviae 9～15 parts, the Fructus Kochiae 9～15 parts, Nidus Vespae 3～9 parts, Fructus Mume 3～9 parts, Fructus Gardeniae 9～15 parts.The present invention compared with the existing technology, devises antianaphylactic Chinese medicine composition and preparation method thereof, for preventing and treating the generation of anaphylactic disease, and the various complication that prevention is caused by anaphylactic disease, there is dual function；And Chinese medicine composition dose is little, taking convenience, and can preferably ensure medicine stability and effect.Its production technology is simple, production cost is low, implementation is strong, it is easy to large-scale industrial production.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicine preparation, a kind of antianaphylactic Chinese medicine composition and preparation side thereof
Method.
Background technology
Anaphylactic disease, mainly includes allergic dermatitis, allergic rhinitis, allergic asthma, anaphylactoid purpura, anaphylaxis
Shocks etc., are owing to anaphylactogen enters human body, start the immunne response that human body is undue, i.e. allergy, involve certain certain organs
Caused by tissue.
At present, normally used for the treatment of anaphylactic disease is oral anti-allergy medicine, such as chlorphenamine
(DIMETINDEN, trade name FENISTIL) tablet or liquor, An Ertai (ATARAX) etc., but this type of oral medicine has necessarily
Sedation, hypohypnosis can be caused, have cause drive a vehicle driving accident danger.Severe allergic patients with rhinitis can be adopted
Taking desensitization treatment (Hyposensibilisierung), this treatment is generally implemented in the autumn and winter season of non-allergy phase.Desensitization is controlled
The success rate treated is 50%.At present in the world anaphylaxis be there is no radical cure way, above-mentioned therapy substantially be suit the medicine to the illness the most not to because of, certain
A little medicine long-term takings there may also be some side effect.Desensitization treatment is theoretically because of therapy, also oversize because taking, about 2-3
Year, patient is difficult to adhere to, actual therapeutic effect is unsatisfactory.
Therefore, still lack at drug world at present a kind of universal effective, treatment anaphylactic disease that toxic and side effects is little
Chinese medicine composition and preparation method thereof.
Summary of the invention
It is an object of the invention to overcome the deficiencies in the prior art, it is provided that one prevents and treats anaphylactic disease effect significantly, secondary
Act on little, can the antiallergic Chinese medicine composition and preparation method thereof of long-term taking.
In order to achieve the above object, the present invention is a kind of antianaphylactic Chinese medicine composition, it is characterised in that: by following weight parts
The raw material of number is made: Radix et Rhizoma Rhei (processed) 9～15 parts, Bombyx Batryticatus 9～15 parts, Periostracum Cicadae 9～15 parts, Zaocys 9～15 parts, Rhizoma Curcumae Longae 9～15 parts,
Fructus Atriplicis Sibiricae 9～15 parts, Radix Saposhnikoviae 9～15 parts, the Fructus Kochiae 9～15 parts, Nidus Vespae 3～9 parts, Fructus Mume 3～9 parts, Fructus Gardeniae 9～15 parts.
Described Radix et Rhizoma Rhei (processed), Bombyx Batryticatus, Periostracum Cicadae, Zaocys, Rhizoma Curcumae Longae, Fructus Atriplicis Sibiricae, Radix Saposhnikoviae, the Fructus Kochiae, Nidus Vespae, Fructus Mume, Fructus Gardeniae
For respective water extract or extractive with organic solvent.
A kind of preparation method of antianaphylactic Chinese medicine composition, it is characterised in that: prepare as follows: step 1, take described
After the Rhizoma Curcumae Longae of parts by weight, Fructus Atriplicis Sibiricae, Radix Saposhnikoviae, Fructus Mume, Fructus Gardeniae are soaked, it is heated to reflux, forms fragrant volatile oil and medicinal liquid, wave
Increase microcrystalline Cellulose mix homogeneously in hair oil, form volatile oil figuration powder；After medicinal liquid filtered while hot, filtrate merges, shape
Become filtrate one.
Step 2, takes the Radix et Rhizoma Rhei (processed) of described parts by weight, Bombyx Batryticatus, Periostracum Cicadae, Zaocys, the Fructus Kochiae, Nidus Vespae boiling, closes
And filter after decocting liquid, form filtrate two.
Step 3, merging filtrate one and filtrate two, filter with organic solvent after concentrating, reclaim organic solvent, be condensed into thick
Cream, drying under reduced pressure is also pulverized, and is subsequently adding volatile oil figuration powder and adjuvant, after mix homogeneously, is dried, granulate and bag
Dress, forms granule.
Described adjuvant is the one in diluent, lubricant, binding agent, disintegrating agent, sweeting agent, stabilizer, preservative
Or more than one mixture.
In described step 1, soaking is 0.5～1 hour, is heated to reflux being 2～3 times, is 1～3 hour every time.
In described step 2, boiling is twice, is 0.5～2 hour for the first time, and second time is 1～3 hour.
In described step 3, organic solvent is ethanol.
In described step 3, concentration condition is 1.08～1.28 for being concentrated into relative density, adds ethanol and makes the alcohol content be
50～70%.
The present invention compared with the existing technology, devises antianaphylactic Chinese medicine composition and preparation method thereof, for preventing and treating allergy
Property disease generation, and the various complication that caused by anaphylactic disease of prevention, there is dual function；And Chinese medicine composition
Dose is little, taking convenience, and can preferably ensure medicine stability and effect.Its production technology is simple, production cost is low,
Implementation is strong, it is easy to large-scale industrial production.
Detailed description of the invention
Now the present invention is described further.
The present invention is a kind of antianaphylactic Chinese medicine composition, is made up of the raw material of following portions by weight: Radix et Rhizoma Rhei (processed) 9～15 parts,
Bombyx Batryticatus 9～15 parts, Periostracum Cicadae 9～15 parts, Zaocys 9～15 parts, Rhizoma Curcumae Longae 9～15 parts, Fructus Atriplicis Sibiricae 9～15 parts, Radix Saposhnikoviae 9～15 parts,
The Fructus Kochiae 9～15 parts, Nidus Vespae 3～9 parts, Fructus Mume 3～9 parts, Fructus Gardeniae 9～15 parts.
Wherein, Radix et Rhizoma Rhei (processed), Bombyx Batryticatus, Periostracum Cicadae, Zaocys, Rhizoma Curcumae Longae, Fructus Atriplicis Sibiricae, Radix Saposhnikoviae, the Fructus Kochiae, Nidus Vespae, Fructus Mume, Fructus Gardeniae are
Respective water extract or extractive with organic solvent.
As it is known by the man skilled in the art, actual in medicine, work is the chemical composition contained by these compositions,
The most above-mentioned each raw material can also is that the extract of these compositions, including water extract and/or extractive with organic solvent, it is considered to
Need easily to drug safety and preparation, preferably its water extract.
The Chinese medicine composition of the present invention both can be used alone, and in order to take conveniently, improves local flavor and the mouthfeel of medicine, excellent
Choosing is pharmaceutical preparation, and Chinese medicine composition and pharmaceutically acceptable carrier including the present invention are prepared from.However, it is necessary to note
Meaning, Chinese medicine composition can also be used alone by the present invention, for example with following method, Chinese medicine composition is made crude drug
For use.
According to above-mentioned parts by weight, use suitable water or organic solvent to extract each raw material, preferably use
Water extracts, and then will be pulverized and mixed after each raw extract combination drying uniformly.
In the present invention, Chinese medicine composition is typically to be prepared as pharmaceutical preparation, and the most pharmaceutically acceptable carrier is to use
In the adjunct ingredient that preparation pharmaceutical preparation is conventional, include but not limited to diluent, lubricant, binding agent, disintegrating agent, sweeting agent,
One or more mixture in stabilizer, preservative etc., for different preparation types, selects different carriers to make
It is apparent to those skilled in the art for adjuvant.
Above-mentioned carrier, its consumption and usage, kind are the openest.Example diluent as mentioned include but
It is not limited to lactose, starch, microcrystalline Cellulose, mannitol etc.；Described lubricant includes but not limited to magnesium stearate, Pulvis Talci
Deng；Described binding agent includes but not limited to polyethylene Topiramate Los oxazolidinone, hydroxypropyl cellulose etc.；Described disintegrating agent include but not
It is limited to carboxymethyl cellulose, acetic acid carboxy starch sodium, polyvinylpolypyrrolidone etc.；Described sweeting agent includes but not limited to sucrose, really
Sugar, Sorbitol etc.；Described stabilizer includes but not limited to sodium carboxymethyl cellulose, cyclodextrin, xanthan gum etc.；Described is anti-
Rotten agent includes but not limited to potassium sorbate, Nipagin ester etc..
Based on above-mentioned adjuvant and other common adjuvants of this area, the Chinese medicine composition of the present invention can be prepared as difference
Pharmaceutical dosage form, include but not limited to powder, tablet, granule, capsule, soft capsule, spray etc..
The present invention prepares granule as follows: step 1, takes the Rhizoma Curcumae Longae of described parts by weight, Fructus Atriplicis Sibiricae, Radix Saposhnikoviae, crow
After prunus mume (sieb.) sieb.et zucc., Fructus Gardeniae are soaked, it is heated to reflux, increases microcrystalline Cellulose in forming fragrant volatile oil and medicinal liquid, volatile oil and mix all
Even, form volatile oil figuration powder；After medicinal liquid filtered while hot, filtrate merges, and forms filtrate one.
Step 2, takes the Radix et Rhizoma Rhei (processed) of described parts by weight, Bombyx Batryticatus, Periostracum Cicadae, Zaocys, the Fructus Kochiae, Nidus Vespae boiling, closes
And filter after decocting liquid, form filtrate two.
Step 3, merging filtrate one and filtrate two, filter with organic solvent after concentrating, reclaim organic solvent, be condensed into thick
Cream, drying under reduced pressure is also pulverized, and is subsequently adding volatile oil figuration powder and adjuvant, after mix homogeneously, is dried, granulate and bag
Dress, forms granule.
In the present invention, method for concentration used and drying means are the method that this area arbitrarily can use, for example with vacuum
Concentrate or room temperature concentrating under reduced pressure, for example with being spray-dried or lyophilization.Method filtrate separated with residue can be
The method that this area arbitrarily can use, the method such as filtering or being centrifuged.
Preferably, in step 1, soaking is 0.5～1 hour, is heated to reflux being 2～3 times, is 1～3 hour every time.
In step 2, boiling is twice, is 0.5～2 hour for the first time, and second time is 1～3 hour.In step 3, organic solvent is
Ethanol.In step 3, concentration condition is 1.08～1.28 for being concentrated into relative density, adds ethanol and makes alcohol content be 50～70%.
Use above-mentioned preferred way, the maximally effective effect that ensure that extraction and the stability of product, and make to produce work
Skill is simple, reduces production cost.
On the basis of the above, the invention also discloses above-mentioned Chinese medicine composition to prevent and treat in anaphylactic disease medicine in preparation
Purposes.The Chinese medicine composition of the present invention may be used for preparing the medicine preventing and treating anaphylactic disease, especially pollen hypersensitivity and/or mistake
The drug desensitization of quick property rhinitis.As it is known by the man skilled in the art, when treating anaphylactic disease, generally have the use of drug combination
Method, therefore by the present invention with other Claritin drug combination to play comprehensive antiallergic, stop multiple sensitization chemistry to be situated between
The effect of matter release is apparent from.
The cure mechanism of the present invention is: the Chinese medicines such as Bombyx Batryticatus, Periostracum Cicadae, Zaocys, Radix Saposhnikoviae, Nidus Vespae, Fructus Mume have antiallergic and make
With.Concrete mechanism is that Bombyx Batryticatus has anticoagulation；Periostracum Cicadae can reduce reflex myotonia reaction, reduce striate tonicity,
Neuroganglion is had slight blocking effect；Radix Saposhnikoviae has inhibitory action to the delayed hypersensitivity caused by DNCB；Nidus Vespae extracting solution and
Zaocys all has inhibitory action to acute and chronic inflammation；Radix Glycyrrhizae has the suppression of similar adrenocortical hormone and mineralocorticoid
Inflammation, anti-allergic effects；Fructus Mume has the effect of relieving cough and moistening lung, and Semen Coicis has the effect etc. of antibacterial detumescence.The Chinese medicine of the present invention
Compositions fully combines modern's dietary habit feature and natural environment feature, and part antiallergic Chinese medicine characteristic, prescription
The Chinese medicinal granule preventing and treating anaphylactic disease formed, has reliable curative effect, has higher safety simultaneously.
Medicament made by the present invention, is taken after mixing it with water by boiled water, one time 10～20 grams (1～3 bag), every day 1～3 times, the course for the treatment of 1
～3 months.According to the practical situation of different cases, can be adjusted correspondingly.
The present invention is for Clinical allergy disease, such as pollinosis patient outcomes: according to the most general pollen hypersensitivity
Disease and allergic rhinitis diagnostic criteria: clinic randomly chooses Allergic Rhinitis 20: perennial onset, have the most continuously
Making a call to more than 3 sneeze, stream thin nasal discharge and three main clinical manifestation of nasal mucosa swelling, number of days of falling ill in a year is accumulative more than 6 months,
In one day, disease time is accumulative more than 0.5 hour；The course of disease at least one year, pollen hypersensitivity patient 20: Seasonal Incidence, every year
Morbidity season is basically identical, and is consistent with pollen pollinating period, within least two years, falls ill in same season, and there is typical case stage of attack
Clinical symptoms and sign, stage of attack nasal discharge and/or conjunctiva scraping blade, eosinophilic granulocyte positive, or nasal mucosa scraping blade loose
The i.e. basophil of cell is positive;, pollen allergen tuerculoderma is positive, at least one be ++ or ++ more than, or become
Should the former nasal provocation test positive, the eye conjunctival butter positive.
Giving the preparation of the pharmaceutical composition of the present invention during anaphylaxis, the medication cycle is one week, three times a day, every time
Dosage is 15g；Matched group chooses 20 pollen allergic patients, 20 Allergic Rhinitis respectively according to above-mentioned standard, respectively
Taking antihistamine drug zyrtec of routine, chemical name: cetirizine dihydrochloride, specification 10mg, use one week continuously, usage is used
Amount specifies according to its description.
Experimental group, in pollen hypersensitivity group, cure or be clearly better 16 people, the effect that take a favorable turn 4 people.In allergic rhinitis group,
Cure or 15 people that are clearly better, the effect that take a favorable turn 4 people, slight or invalid 1 people of effect.Matched group, in pollen hypersensitivity group, cure or
Be clearly better 4 people, the effect that take a favorable turn 5 people, slight or invalid 11 people of effect.In allergic rhinitis group, cure or be clearly better 2
People, the effect that take a favorable turn 4 people, slight or invalid 14 people of effect.
It was found that, the Chinese medicine composition of the present invention can take effect after taking half an hour, effect is notable.From the above
It can be seen that the Chinese medicine composition of the present invention is respectively provided with for pollen allergic patients and Allergic Rhinitis significantly treats effect
Really.
Claims (8)
1. an antianaphylactic Chinese medicine composition, it is characterised in that: it is made up of the raw material of following portions by weight: Radix et Rhizoma Rhei (processed) 9～15 parts,
Bombyx Batryticatus 9～15 parts, Periostracum Cicadae 9～15 parts, Zaocys 9～15 parts, Rhizoma Curcumae Longae 9～15 parts, Fructus Atriplicis Sibiricae 9～15 parts, Radix Saposhnikoviae 9～15 parts,
The Fructus Kochiae 9～15 parts, Nidus Vespae 3～9 parts, Fructus Mume 3～9 parts, Fructus Gardeniae 9～15 parts.
A kind of antianaphylactic Chinese medicine composition the most as claimed in claim 1, it is characterised in that: described Radix et Rhizoma Rhei (processed), Bombyx Batryticatus, Cicadae
Clothing, Zaocys, Rhizoma Curcumae Longae, Fructus Atriplicis Sibiricae, Radix Saposhnikoviae, the Fructus Kochiae, Nidus Vespae, Fructus Mume, Fructus Gardeniae are respective water extract or organic solvent carries
Take thing.
3. the preparation method of an antianaphylactic Chinese medicine composition as claimed in claim 1, it is characterised in that: make as follows
Standby: step 1, take the Rhizoma Curcumae Longae of described parts by weight, after Fructus Atriplicis Sibiricae, Radix Saposhnikoviae, Fructus Mume, Fructus Gardeniae soak, be heated to reflux, form perfume
Volatile oil and medicinal liquid, increase microcrystalline Cellulose mix homogeneously, form volatile oil figuration powder in volatile oil；Medicinal liquid filtered while hot
After, filtrate merges, and forms filtrate one；Step 2, take the Radix et Rhizoma Rhei (processed) of described parts by weight, Bombyx Batryticatus, Periostracum Cicadae, Zaocys, the Fructus Kochiae,
Nidus Vespae boiling, filters after collecting decoction, forms filtrate two；Step 3, merging filtrate one and filtrate two, filter with organic solvent
After crossing concentration, reclaiming organic solvent, be condensed into thick paste, drying under reduced pressure is also pulverized, and is subsequently adding volatile oil figuration powder and adjuvant,
After mix homogeneously, it is dried, granulate and packaging, forms granule.
The preparation method of a kind of antianaphylactic Chinese medicine composition the most as claimed in claim 3, it is characterised in that: described adjuvant is
One or more mixture in diluent, lubricant, binding agent, disintegrating agent, sweeting agent, stabilizer, preservative.
The preparation method of a kind of antianaphylactic Chinese medicine composition the most as claimed in claim 3, it is characterised in that: described step 1
In, soaking is 0.5～1 hour, is heated to reflux being 2～3 times, is 1～3 hour every time.
The preparation method of a kind of antianaphylactic Chinese medicine composition the most as claimed in claim 3, it is characterised in that: described step 2
In, boiling is twice, is 0.5～2 hour for the first time, and second time is 1～3 hour.
The preparation method of a kind of antianaphylactic Chinese medicine composition the most as claimed in claim 3, it is characterised in that: described step 3
In, organic solvent is ethanol.
The preparation method of a kind of antianaphylactic Chinese medicine composition the most as claimed in claim 3, it is characterised in that: described step 3
In, concentration condition is 1.08～1.28 for being concentrated into relative density, adds ethanol and makes alcohol content be 50～70%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610688426.XA CN106075315A (en) | 2016-08-19 | 2016-08-19 | A kind of antianaphylactic Chinese medicine composition and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610688426.XA CN106075315A (en) | 2016-08-19 | 2016-08-19 | A kind of antianaphylactic Chinese medicine composition and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106075315A true CN106075315A (en) | 2016-11-09 |
Family
ID=58069939
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610688426.XA Withdrawn CN106075315A (en) | 2016-08-19 | 2016-08-19 | A kind of antianaphylactic Chinese medicine composition and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106075315A (en) |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1343506A (en) * | 2000-09-15 | 2002-04-10 | 海国灿 | Chinese patent medicine for treating allergic dermatopathy |
| CN101032590A (en) * | 2007-04-04 | 2007-09-12 | 王欣 | Chinese medicinal composition to be taken orally for curing eczema |
| CN102526546A (en) * | 2012-01-04 | 2012-07-04 | 田胜利 | Chinese medicinal composition and preparation and preparation method thereof |
| CN103393802A (en) * | 2013-08-13 | 2013-11-20 | 台州标盟知识产权代理有限公司 | Tradtional Chinese medicine composition for treating cholinergic urticaria |
| CN103463254A (en) * | 2013-08-26 | 2013-12-25 | 荣成市科学技术情报研究所 | Traditional Chinese medicine composition for treating allergic rhinitis |
| CN104940760A (en) * | 2015-06-10 | 2015-09-30 | 青州市食用菌研究所 | Four compositions for preventing and treating acute epidemic disease and preparation processes thereof |
-
2016
- 2016-08-19 CN CN201610688426.XA patent/CN106075315A/en not_active Withdrawn
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1343506A (en) * | 2000-09-15 | 2002-04-10 | 海国灿 | Chinese patent medicine for treating allergic dermatopathy |
| CN101032590A (en) * | 2007-04-04 | 2007-09-12 | 王欣 | Chinese medicinal composition to be taken orally for curing eczema |
| CN102526546A (en) * | 2012-01-04 | 2012-07-04 | 田胜利 | Chinese medicinal composition and preparation and preparation method thereof |
| CN103393802A (en) * | 2013-08-13 | 2013-11-20 | 台州标盟知识产权代理有限公司 | Tradtional Chinese medicine composition for treating cholinergic urticaria |
| CN103463254A (en) * | 2013-08-26 | 2013-12-25 | 荣成市科学技术情报研究所 | Traditional Chinese medicine composition for treating allergic rhinitis |
| CN104940760A (en) * | 2015-06-10 | 2015-09-30 | 青州市食用菌研究所 | Four compositions for preventing and treating acute epidemic disease and preparation processes thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102895432A (en) | Prescription and preparation method of rejoicing powder having new dosage form | |
| CN103830535B (en) | Pharmaceutical composition for the treatment of rhinitis and its production and use | |
| WO2014094632A1 (en) | Pharmaceutical composition for treating headache, and preparation method thereof | |
| CN102526546A (en) | Chinese medicinal composition and preparation and preparation method thereof | |
| CN104666373A (en) | Novel use of Eurycoma longifolia Jack | |
| CN101129588A (en) | Medicinal granules for conjunctivitis | |
| CN102657834A (en) | Traditional Chinese medical composition for treatment of alcoholism and preparation process thereof | |
| JP2002154979A (en) | Medicine composition for i type allergy and method for producing the same | |
| CN107890528B (en) | Traditional Chinese medicine composition for treating hyperuricemia and preparation method thereof | |
| CN104436145B (en) | It is a kind of to prevent and/or treatment allergic rhinitis and the pharmaceutical composition of allergic asthma | |
| CN106362004A (en) | Compound fresh dendrobium nobile granules and preparation method thereof | |
| CN102579870A (en) | Traditional Tibetan medicine composition and preparation for treating liver diseases, and preparation method thereof | |
| CN101019926A (en) | Chinese medicine for treating cardiac and cerebral vascular diseases and its prepn process | |
| CN106075315A (en) | A kind of antianaphylactic Chinese medicine composition and preparation method thereof | |
| CN102166282B (en) | Anti-allergic or desensitized pharmaceutical composition | |
| CN111150774A (en) | Application of black nightshade fruit in preventing and treating new coronavirus or influenza virus infection | |
| CN110559322A (en) | Sea-buckthorn compound hard capsule for treating depression and preventing anxiety depression and preparation method thereof | |
| CN103800449B (en) | A kind of Chinese medicine composition for the treatment of Yin Xu Nei Re Zheng type 2 diabetes mellitus | |
| CN112641855B (en) | A Chinese medicinal composition for treating or preventing common cold, and its preparation method | |
| CN108379395A (en) | A kind of clear pest anti virus herb composition | |
| CN112089810B (en) | Medicine for treating glaucoma and preparation method thereof | |
| CN102302655A (en) | Loquat acne removing capsules | |
| CN107929374B (en) | Preparation method of traditional Chinese medicine preparation for treating senile dementia | |
| CN107213343A (en) | A kind of canker sore Chinese medicine ointment containing bletilla and preparation method thereof | |
| CN102166329A (en) | Medicine for treating leukopenia caused by chronic hepatitis B or interferon and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20161109 |