CN1343506A - Chinese patent medicine for treating allergic dermatopathy - Google Patents

Chinese patent medicine for treating allergic dermatopathy Download PDF

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Publication number
CN1343506A
CN1343506A CN00128926A CN00128926A CN1343506A CN 1343506 A CN1343506 A CN 1343506A CN 00128926 A CN00128926 A CN 00128926A CN 00128926 A CN00128926 A CN 00128926A CN 1343506 A CN1343506 A CN 1343506A
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chinese patent
radix
patent medicine
flos
cortex
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CN1124145C (en
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海国灿
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Abstract

A Chinese patent medicine for treating allergic dermatopathy is prepared from 15 Chinese-medicinal materials including scorpion, centipede, red peony root, earthworm, etc. through crushing, proportioning and preparing capsules or pills. Its advantages include high curative effect, and no residual black scar.

Description

A kind of Chinese patent medicine for the treatment of anaphylaxis dermatosis
The invention belongs to the Chinese patent medicine of treatment anaphylaxis dermatosis, promptly treat eczema, drug eruption, allergic dermatitis, prurigo, prurigo nodularis, urticarial Chinese patent medicine.
Anaphylaxis dermatosis is difficult stubborn disease, though the Chinese patent medicine of treatment anaphylaxis dermatosis is arranged now, effect is not fairly obvious, and curative effect is not as good as Western medicine, and allergic skin case patient has to adopt Western medicine, and Western medicine can not thoroughly effect a radical cure, and stays the black ecchymosis.
Purport of the present invention refers to provide a kind of Chinese patent medicine good to the anaphylaxis dermatosis therapeutic effect, with not staying the black ecchymosis after the treatment of this medicine.
Chinese patent medicine of the present invention is made by following component: (consumption is a weight portion) Scorpio 4-6 Scolopendra 3-5 Zaocys 13-17 Radix Paeoniae Rubra 13-17 Pheretima 13-17 Bombyx Batryticatus 8-12 Periostracum Cicadae 8-12 Radix Angelicae Sinensis 22-28 Flos Lonicerae 22-28 Radix Polygoni Multiflori 22-28 Cortex Lycii 22-28 Flos Chrysanthemi Indici 22-28 Radix Sophorae Flavescentis 13-17 Cortex Dictamni 27-33 Flos Carthami 8-12
The optimum ratio scope of Chinese patent medicine formula of the present invention is: (consumption is a weight portion) Scorpio 4-6 Scolopendra 3-5 Zaocys 14-16 Radix Paeoniae Rubra 14-16 Pheretima 14-16 Bombyx Batryticatus 9-11 Periostracum Cicadae 9-11 Radix Angelicae Sinensis 23-27 Flos Lonicerae 23-27 Radix Polygoni Multiflori 23-27 Cortex Lycii 23-27 Flos Chrysanthemi Indici 23-27 Radix Sophorae Flavescentis 14-16 Cortex Dictamni 28-32 Flos Carthami 9-11
The optimum weight of Chinese patent medicine of the present invention (part) proportioning is: Scorpio 5 Scolopendras 4 Zaocys 15 Radix Paeoniae Rubra 15 Pheretimas 15 Bombyx Batryticatus 10 Periostracum Cicadaes 10 Radix Angelicae Sinensis 25 Flos Lonicerae 25 Radix Polygoni Multifloris 25 Cortex Lycii 25 Flos Chrysanthemi Indicis 25 Radix Sophorae Flavescentiss 15 Cortex Dictamnis 30 Flos Carthamis 10
In the above-mentioned component:
Zaocys used weight part is that 9 parts Agkistrodon substitutes, Radix Paeoniae Rubra can substitute with the Cortex Moutan of equivalent or both shared effects better; Periostracum Cicadae can be with any substitutes in the Herba Schizonepetae of equivalent, Fructus Atriplicis Sibiricae, Radix Saposhnikoviae, the Periostracum Serpentis, but and compatibility and using; Radix Angelicae Sinensis can substitute or both are shared with the Radix Astragali of 35 weight portions; Flos Lonicerae can substitute with Caulis Lonicerae, the Fructus Forsythiae of equivalent; Cortex Dictamni used weight part is that the Fructus Kochiae of Cortex Dictamni 1/2nd is alternative or both are shared, and also available Rhizoma Atractylodis, Cortex Phellodendri, Fructus Cnidii substitute (weight is referring to embodiment); Flos Carthami can use drug for invigorating blood circulation and eliminating stasis such as Semen Persicae, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae to substitute.
In the above-mentioned component, the function of Scorpio, Scolopendra is suppressing liver-wind to relieve spasm, dispersing pathogen accumulation, pharmacology analysis, and Scorpio has blood vessel dilating, hypotensive effect, and Scolopendra contains H-subst and hemolytic protein.The function of Zaocys is a wind-damp dispelling, and arresting convulsion is jerked.The function of Radix Sophorae Flavescentis is a heat clearing and damp drying, killing parasites for relieving itching, tonneau urine.Pharmacology analysis has diuresis, and some common funguses and infusorian are had inhibitory action in various degree.The function of Cortex Dictamni is the dampness heat-clearing and toxic substances removing, and pharmacology is the water logging agent has in various degree inhibitory action to multiple pathomycete.The function of the Fructus Kochiae is a clearing away damp-heat, diuresis, dispelling wind for relieving itching.The function clearing away heat and cooling blood of Radix Paeoniae Rubra, eliminating stasis to stop pain, fire is let out in liver heat removing.Pharmacology: paeoniflorin has spasmolysis preferably, and blood pressure lowering is arranged, effects such as coronary blood flow increasing and antalgic and sedative, anti-frightened Jue, antiinflammatory, antiulcer; Strong bacteriostasis is arranged, influenza virus is also had certain inhibitory action.The function of Pheretima is the heat clearing away arresting convulsion, clearing lung, relieving asthma, the collateral dredging of passing through.Pharmacology is that lumbrifebrine has good refrigeration function.The function of the Radix Astragali is a tonifying Qi and lifting yang, and the QI invigorating row stagnates, strengthening superficial resistance to stop perspiration, holder skin ulcer granulation promoting, diuresis detumescent.Pharmacology: the blood vessel dilating effect is arranged, can improve cutaneous circulation and nutriture, bring high blood pressure down diuresis.Also have the liver protecting, prevent the effect that liver glycogen reduces.The Cortex Moutan function is a clearing away heat and cooling blood, promoting blood circulation to remove blood stasis.The function of Flos Carthami, promoting blood circulation to restore menstrual flow, reducing swelling and alleviating pain.The function of Bombyx Batryticatus is for dispeling the wind, and expelling wind to relieve convulsion reduces phlegm, dispelling pathogenic wind and eliminating phlegm, dispersing swelling and dissipating binds.The function of Periostracum Cicadae is a dispelling wind and heat pathogens, and rash is antipruritic, improving acuity of vision and removing nebula, expelling wind to relieve convulsion.The function of Radix Angelicae Sinensis is invigorated blood circulation for enriching blood, promoting the circulation of QI to relieve pain; Loosening bowel to relieve constipation.The function of Flos Lonicerae is a heat-clearing and toxic substances removing, dispelling wind and heat pathogens.Pharmacology: various bacteria is had in various degree inhibitory action.Dermatophytes and leptospira also there are inhibition usefulness, reduce the tired absorption of intestinal, can slightly prevent gastric ulcer cholesterol.The function of Radix Polygoni Multiflori be enrich and benefit essence and blood power a little less than, but the diffusing merit of row is arranged, but double preventing the attack (or recurrence) of malaria, detoxifcation, loosening bowel to relieve constipation.The function of Cortex Lycii is a clearind deficient heat, the lung heat clearing fire, and cooling blood for hemostasis, pharmacology: blood pressure lowering is arranged, decreased heart rate, accelerated breathing, the blocking-up sympathetic nerve does not reach direct vasodilator slightly, blood sugar lowering, effect such as bring down a fever.The function of Flos Chrysanthemi Indici is a dispelling wind and heat pathogens, makes eye bright pancake liver-yang, heat-clearing and toxic substances removing.Pharmacology: bacillus, coccus, fungus are had in various degree inhibitory action, can suppress capillary permeability and antiinflammatory action is arranged.
The synergism of each component is as follows in this Chinese patent medicine: Scorpio, Scolopendra, Pheretima, Zaocys, Bombyx Batryticatus, Periostracum Cicadae have the effect of the detoxifying and relieving itching of dispeling the wind: Radix Sophorae Flavescentis, Cortex Dictamni, the Fructus Kochiae, the Radix Astragali, Cortex Moutan, Flos Carthami, Radix Paeoniae Rubra, Radix Angelicae Sinensis, Flos Lonicerae, Radix Polygoni Multiflori, Cortex Lycii, Flos Chrysanthemi Indici have the dampness dissipating blood stasis, promoting blood circulation and cooling blood, the effect that the QI invigorating row stagnates.
Production technology: with Chinese medicine material drying and crushing to the 100 order fine powder of above-mentioned component.Thin medicated powder is made capsule with common process, and every contains medicated powder 0.45g-0.5g.Also can be made into the watered pill.Also available conventional formulation technology is made powder or oral liquid.
Chinese patent medicine of the present invention shows that through clinical use result following advantage is arranged:
1, this Chinese patent medicine is a raw material with plant, animal Chinese crude drug, and wherein four kinds contain toxicity animal dosage and meet the provisions of the relevant regulations issued by the State.
2, this Chinese patent medicine can replace expensive import Western medicine, can effect a radical cure the black speck of leaving over behind the western medicine.
For showing the therapeutic effect of Chinese patent medicine of the present invention to anaphylaxis dermatosis, Chinese patent medicine of the present invention is through the clinical observation of 1232 routine systems.Wherein male 801 examples, women 431 examples, the age between 4 to 85 years old, the course of disease 2 years to 50 years.3 months observation periods, a week is a course of treatment, and take effect a general course of treatment, general four courses of treatment.
Instructions of taking: 9 gram/days, 3 grams/time, every day three times, each oral 6 capsules.Also can the oral watered pill, every day three times, each 2g-3g.
The clinical efficacy standard
Recovery from illness is rotten to the corn, ooze out, crust, erythema pimple, squama, pruritus transference cure, and it is ruddy originally that skin recovers.
Produce effects was treated through half a year, rotten to the corn, ooze out stop, squama comes off, still have new erythema pimple to occur, the pruritus symptom does not disappear.
Invalid erosion, ooze out and continue development, new erythema pimple occurs, and violent pruritus symptom is still deposited.
According to above-mentioned standard, the clinical efficacy result such as the following table of this Chinese patent medicine.
The sick kind Total routine number Recovery from illness Produce effects Invalid
Number Percentage ratio Number Percentage ratio Number Percentage ratio
Eczema 400 ?340 ?85% 60 ?15% 0 ?0
Drug eruption 56 ?50 ?89.2% 6 ?10.7% 0 ?0
Allergic dermatitis 78 ?69 ?88.4% 9 ?11.5% 0 ?0
Prurigo 223 ?212 ?95% 11 ?4.5% 0 ?0
Prurigo nodularis 189 ?186 ?98% 3 ?1% 0 ?0
Urticaria 286 ?283 ?98.1% 3 ?1% 0 ?0
Find out from the clinical efficacy structural table, this Chinese patent medicine evident in efficacy, none example is invalid.
Followingly describe Chinese patent medicine of the present invention in detail, but Chinese patent medicine of the present invention is not limited to embodiment according to embodiment.
The weight of embodiment one (part) proportioning is: Scorpio 5 Scolopendras 4 Zaocys 15 Radix Paeoniae Rubra 15 Pheretimas 15 Bombyx Batryticatus 10 Periostracum Cicadaes 10 Radix Angelicae Sinensis 25 Flos Lonicerae 25 Radix Polygoni Multifloris 25 Cortex Lycii 25 Flos Chrysanthemi Indicis 25 Radix Sophorae Flavescentiss 15 Cortex Dictamnis 30 Flos Carthamis 10
Embodiment two is to be Flos Lonicerae in 25 the Caulis Lonicerae alternate embodiment one with weight portion.Flos Lonicerae among also alternative other embodiment.
Embodiment three is that to add weight portion on the basis of embodiment one be 15 the Fructus Kochiae.Also can on the basis of other embodiment, add weight portion and be 15 the Fructus Kochiae.
According to tcm theory, the Chinese patent medicine of this treatment anaphylaxis dermatosis also can be formed following main
Embodiment.
Embodiment four and not existing together of embodiment one are the Radix Paeoniae Rubra with in 15 parts the Cortex Moutan alternate embodiment one.Radix Paeoniae Rubra among also alternative other embodiment.
Embodiment five increases by 15 parts Cortex Moutan on the basis of embodiment one.Also can on the basis of other embodiment, increase by 15 parts Cortex Moutan.
Embodiment six is with the Zaocys in the Agkistrodon alternate embodiment one of 9 weight portions.Zaocys among also alternative other embodiment.
Embodiment seven, embodiment eight, embodiment nine, embodiment ten are Periostracum Cicadaes of choosing successively respectively in Herba Schizonepetae, Fructus Atriplicis Sibiricae, Radix Saposhnikoviae, the Periostracum Serpentis difference alternate embodiment one, and the weight portion of choosing is 10 parts.Periostracum Cicadae among also alternative other embodiment.
Embodiment 11 is to be Radix Angelicae Sinensis in 35 the Radix Astragali alternate embodiment one with weight portion.Radix Angelicae Sinensis among also alternative other embodiment.
Embodiment 12 is that to add weight portion on the basis of embodiment one be 35 the Radix Astragali.The Radix Astragali among also alternative other embodiment.
Embodiment 13 is to be Flos Lonicerae in 25 the Fructus Forsythiae alternate embodiment one with weight portion.Flos Lonicerae among also alternative other embodiment.
Embodiment 14 is the Fructus Forsythiaes that add weight portion 25 on the basis of embodiment one.The Fructus Forsythiae that also can on the basis of embodiment, add weight portion 25.
Embodiment 15 is to be Cortex Dictamni in 15 the Fructus Kochiae alternate embodiment one with weight portion.Cortex Dictamni among also alternative other embodiment.
Embodiment 16 is to be Cortex Dictamni in 18 the Rhizoma Atractylodis alternate embodiment one with weight portion.Cortex Dictamni among also alternative other embodiment.
Embodiment 17 is to be Cortex Dictamni in 30 the Cortex Phellodendri alternate embodiment one with weight portion.Cortex Dictamni among also alternative other embodiment.
Embodiment 18 is to be Cortex Dictamni in 30 the Fructus Cnidii alternate embodiment one with weight portion.Cortex Dictamni among also alternative other embodiment.
Embodiment 19 is to be Flos Carthami in 10 the Semen Persicae alternate embodiment one with weight portion.Flos Carthami among also alternative other embodiment.
Embodiment 20 is to be Flos Carthami in 10 the Rhizoma Chuanxiong alternate embodiment one with weight portion.Flos Carthami among also alternative other embodiment.
Embodiment 21 is to be Flos Carthami in 10 the Radix Salviae Miltiorrhizae alternate embodiment one with weight portion.Flos Carthami among also alternative other embodiment.
The weight portion of the medical material of above-mentioned various embodiment is 2kg, drying and crushing to 100 order fine powder.Thin medicated powder routinely technology make capsule, every contains medicated powder 0.45g-0.5g.Also can make the watered pill routinely.Also available conventional formulation technology is made powder or oral liquid.

Claims (7)

1, a kind of Chinese patent medicine for the treatment of anaphylaxis dermatosis is characterized in that it is the medicament Scorpio 4-6 Scolopendra 3-5 Zaocys 13-17 Radix Paeoniae Rubra 13-17 Pheretima 13-17 Bombyx Batryticatus 8-12 Periostracum Cicadae 8-12 Radix Angelicae Sinensis 22-28 Flos Lonicerae 22-28 Radix Polygoni Multiflori 22-28 Cortex Lycii 22-28 Flos Chrysanthemi Indici 22-28 Radix Sophorae Flavescentis 13-17 Cortex Dictamni 27-33 Flos Carthami 8-12 that is made by the following weight proportion raw material
2, the Chinese patent medicine of treatment anaphylaxis dermatosis according to claim 1, the weight proportion that it is characterized in that each raw material are Scorpio 4-6 Scolopendra 3-5 Zaocys 14-16 Radix Paeoniae Rubra 14-16 Pheretima 14-16 Bombyx Batryticatus 9-11 Periostracum Cicadae 9-11 Radix Angelicae Sinensis 23-27 Flos Lonicerae 23-27 Radix Polygoni Multiflori 23-27 Cortex Lycii 23-27 Flos Chrysanthemi Indici 23-27 Radix Sophorae Flavescentis 14-16 Cortex Dictamni 28-32 Flos Carthami 9-11
3, Chinese patent medicine according to claim 2, the weight proportion that it is characterized in that each raw material are Scorpio 5 Scolopendras 4 Zaocys 15 Radix Paeoniae Rubra 15 Pheretimas 15 Bombyx Batryticatus 10 Periostracum Cicadaes 10 Radix Angelicae Sinensis 25 Flos Lonicerae 25 Radix Polygoni Multifloris 25 Cortex Lycii 25 Flos Chrysanthemi Indicis 25 Radix Sophorae Flavescentiss 15 Cortex Dictamnis 30 Flos Carthamis 10
4, the Chinese patent medicine of treatment anaphylaxis dermatosis according to claim 3 is characterized in that: be to be that 25 Caulis Lonicerae substitutes Flos Lonicerae wherein with weight portion.
5, the Chinese patent medicine according to claim 3 treatment anaphylaxis dermatosis is characterized in that: add weight portion again and be 15 the Fructus Kochiae.
6, are described Chinese patent medicines according to claim 1 or 2 or 3 or 4 or 5, it is characterized in that said medicament is said any dosage form on the pharmaceutics.
7, Chinese patent medicine according to claim 6 is characterized in that said dosage form is the capsule or the watered pill.
CN00128926A 2000-09-15 2000-09-15 Chinese patent medicine for treating allergic dermatopathy Expired - Fee Related CN1124145C (en)

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