CN105288341A - Traditional Chinese medicine oral liquid for treating allergic dermatitis and preparation method - Google Patents
Traditional Chinese medicine oral liquid for treating allergic dermatitis and preparation method Download PDFInfo
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- CN105288341A CN105288341A CN201510759266.9A CN201510759266A CN105288341A CN 105288341 A CN105288341 A CN 105288341A CN 201510759266 A CN201510759266 A CN 201510759266A CN 105288341 A CN105288341 A CN 105288341A
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Abstract
The invention discloses traditional Chinese medicine oral liquid for treating allergic dermatitis and a preparation method. The traditional Chinese medicine oral liquid is prepared from, by weight, 10-14 parts of herba schizonepetae, 28-32 parts of caulis spatholobi, 38-42 parts of semen coicis, 13-17 parts of periostracum cicada, 28-32 parts of semen sesami nigrum, 8-12 parts of safflower, 13-17 parts of zaocys dhumnade, 18-22 parts of prepared fleece flower roots, 13-17 parts of prepared rehmannia roots, 28-32 parts of fructus kochiae, 18-22 parts of lithospermum, 8-12 parts of cocklebur fruits, 23-27 parts of dittany bark, 18-22 parts of roses and 4-8 parts of liquorice. The traditional Chinese medicine oral liquid has the effects of dispelling wind and arresting itching, clearing heat and promoting dieresis and achieving detoxication and killing bacteria, and is a traditional Chinese medicine composition which is safe, reliable, free of any toxic and side effect, high in effective ingredient use rate and fast in effect taking.
Description
Technical field
The present invention relates to a kind of Chinese medicine oral liquid for the treatment of allergic dermatitis, belong to the field of Chinese medicines.
Background technology
Allergic dermatitis is the dermatosis caused by anaphylactogen, mainly refer to the skin disorders such as human contact causes red swelling of the skin, itches to some anaphylactogen, welt, decortication, it is a large class disease in dermatosis, symptom can have redness, itches, bitterly, especially the most obvious with pruritus, the cause of disease can be divided into constitutional to stimulate and allergy two kinds 1. PICD: contactant has very strong zest to skin, and anyone all dermatitis can occur after contacting, and is called that constitutional stimulates.Constitutional stimulation is divided into two kinds, and a kind of zest is very strong, falls ill after contact in the short time, another kind is more weak, and long period contact sequela, as soap, organic solvent etc., 2. allergic contact dermatitis: contactant is non-stimulated substantially, after a few peoples contact this material sensitization, again contact this material, through 12-48 hour contact site and near generation dermatitis, the material of contact dermatitis can be caused a lot, mainly contain animality, vegetalitas and chemical three kinds, the western medical treatment Main Means taked this disease at present takes antibiotic, but western medicine is temporary transient symptom management mostly, and it is harmful unhelpful to take too many antibiotic, because abuse of antibiotics may cause bottleneck throat normal flora to be lacked of proper care, and resistance can be caused to strengthen, immune function of human body goes down, cause Relapse rate difficulty more.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide a kind of Chinese medicine oral liquid for the treatment of allergic dermatitis, it has effect of dispelling wind for relieving itching, clearing away heat-damp and promoting diuresis, detoxicating, killing bacteria.
The present invention is achieved through the following technical solutions:
Treat a Chinese medicine oral liquid for allergic dermatitis, be made up of following raw material: Herba Schizonepetae 10-14 part, Caulis Spatholobi 28-32 part, Semen Coicis 38-42 part, Periostracum Cicadae 13-17 part, Semen Sesami Nigrum 28-32 part, Flos Carthami 8-12 part, Zaocys 13-17 part, Radix Polygoni Multiflori Preparata 18-22 part, Radix Rehmanniae Preparata 13-17 part, Fructus Kochiae 28-32 part, Radix Arnebiae (Radix Lithospermi) 18-22 part, Fructus Xanthii 8-12 part, Cortex Dictamni 23-27 part, Flos Rosae Rugosae 18-22 part, Radix Glycyrrhizae 4-8 part.
Preferably, each parts by weight of raw materials is: Herba Schizonepetae 12 parts, Caulis Spatholobi 30 parts, Semen Coicis 40 parts, Periostracum Cicadae 15 parts, Semen Sesami Nigrum 30 parts, 10 parts, Flos Carthami, Zaocys 15 parts, Radix Polygoni Multiflori Preparata 20 parts, Radix Rehmanniae Preparata 15 parts, the Fructus Kochiae 30 parts, Radix Arnebiae (Radix Lithospermi) 20 parts, Fructus Xanthii 10 parts, Cortex Dictamni 25 parts, Flos Rosae Rugosae 20 parts, 6 parts, Radix Glycyrrhizae.
Pharmacological action:
Herba Schizonepetae: nature and flavor with return through: pungent, tepor; Return lung, Liver Channel, function with cure mainly: induce sweat loose wind, rash; For flu, headache, measles, rubella, skin infection from the beginning of; Parch to black treating hematochezia, metrorrhagia, puerperal blood faints.
Caulis Spatholobi: nature and flavor with return through: bitter, sweet, temperature; Return liver, kidney channel, function with cure mainly: enrich blood, invigorate blood circulation, dredging collateral; For menoxenia, blood deficiency and yellow complexion, paralysis and numbness, rheumatic arthralgia.
Semen Coicis: nature and flavor with return through: sweet, light, cool; Return spleen, stomach, lung meridian, function with cure mainly: spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal, heat clearing away row dense; For edema, beriberi, dysuria, arthralgia chiefly caused by damp pathogen contracture, diarrhea due to hypofunction of the spleen, lung abscess, intestinal carbuncle; Verruca plana.
Periostracum Cicadae: nature and flavor with return through: sweet, cold; Return lung, Liver Channel, function with cure mainly: loose wind heat extraction, sore-throat relieving, rash, nebula removing, spasmolytic; For anemopyretic cold, pharyngalgia, hoarseness, measles without adequate eruption, rubella pruritus, cataract, convulsion with spasms, tetanus.
Semen Sesami Nigrum: nature and flavor with return through: sweet, flat; Return liver, kidney, large intestine channel, function with cure mainly: invigorating the liver and kidney, benefiting essence-blood, intestine moistening is dry; For dizziness and blurred vision, Hiccough and deaf, early whitening of beard and hair, post disease alopecia, dryness of the intestine constipation.
Flos Carthami: nature and flavor with return through: pungent, temperature; GUIXIN, Liver Channel, function with cure mainly: promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain; For amenorrhea, dysmenorrhea, lochia, note of the ancient Chinese abdominal mass mass in the abdomen, injury from falling down, skin infection swells and ache.
Zaocys: nature and flavor with return through: sweet, flat; Return Liver Channel, function with cure mainly: dispel the wind, dredging collateral, relieving convulsion; For rheumatoid arthritis stubborn, numbness contracture, apoplexy facial hemiparalysis, hemiplegia, tic spasm, tetanus, leprosy scabies, scrofula malignant boil.
Radix Polygoni Multiflori Preparata: nature and flavor with return through: bitter, sweet, puckery, tepor; Return liver, the heart, kidney channel; Function with cure mainly: invigorating the liver and kidney, benefiting essence-blood, black beard and hair, bone and muscle strengthening, changes turbid blood fat reducing; For blood deficiency and yellow complexion, vertigo and tinnitus. early whitening of beard and hair, soreness of the waist and knees, numb limbs and tense tendons, bleeding not during menses, hyperlipemia.
Radix Rehmanniae Preparata: nature and flavor with return through: sweet, tepor; Return liver, kidney channel; Function with cure mainly: nourishing YIN and supplementing blood, beneficial essence fills out marrow; For the hepatic and renal YIN deficiency, soreness of the waist and knees, osteopyrexia and fever, night sweat is passed out semen, and interior-heat is quenched one's thirst, blood deficiency and yellow complexion, severe palpitation, menoxenia, and metrostaxis is dizzy, tinnitus, early whitening of beard and hair.
The Fructus Kochiae: nature and flavor with return through: pungent, bitter, cold; Return kidney, urinary bladder channel, function with cure mainly: clearing away heat-damp and promoting diuresis, dispelling wind for relieving itching; For difficulty and pain in micturition, pudendal pruritus leukorrhagia, rubella, eczema, skin pruritus.
Radix Arnebiae (Radix Lithospermi): nature and flavor with return through: sweet, salty, cold; GUIXIN, Liver Channel, function with cure mainly: removing heat from blood, invigorate blood circulation, detoxicating, killing bacteria; Contain for heat in blood poison, macule purple is black, measles without adequate eruption, skin infection, eczema, burn due to hot liquid or fire.
Fructus Xanthii: nature and flavor with return through: pungent, bitter, temperature; Poisonous; Return lung meridian, function with cure mainly: loose wind dehumidifies, clearing the nasal passage; For headche due to wind-cold, nasal sinusitis watery nasal discharge, rubella pruritus, arthralgia chiefly caused by damp pathogen contracture.
Cortex Dictamni: nature and flavor hardship is salty, cold; Gui Jing enters spleen, stomach warp; Function cures mainly: dispel the wind, dampness, heat clearing away, removing toxic substances; Control wind heat sore, scabies, itchy skin eruption, rheumatic arthralgia, jaundice.
Flos Rosae Rugosae: nature and flavor with return through sweet, micro-hardship, temperature; Return liver, spleen channel, function with cure mainly: promoting QI circulation for relieving depression, and blood, pain relieving; For stomachache due to hyperactive liver-QI attacking the stomach, lack of appetite vomiting and nausea, menoxenia, falls and flutters the pain of injury.
Radix Glycyrrhizae: nature and flavor with return through: sweet, flat; GUIXIN, lung, spleen, stomach warp, function with cure mainly: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription; For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Another technical problem to be solved by this invention is to provide a kind of preparation method preparing above-mentioned Chinese medicine oral liquid.
Another technical problem to be solved by this invention is achieved through the following technical solutions:
Treat a preparation method for the Chinese medicine oral liquid of allergic dermatitis, be prepared from by following methods:
(1) raw material Semen Sesami Nigrum, Flos Carthami, Flos Rosae Rugosae, Radix Arnebiae (Radix Lithospermi) cold water soak 10-30 minute is got, then put into decocting machine and decoct with water twice, first time adds above-mentioned raw material weight and 6-10 soak by water 1-2 hour doubly, second time adds above-mentioned raw materials weight and 5-8 soak by water 1-2 hour doubly, collecting decoction, filters, and collects filtrate, obtain filtrate, for subsequent use;
(2) raw material Herba Schizonepetae, Caulis Spatholobi, Semen Coicis, Periostracum Cicadae, Zaocys, Radix Polygoni Multiflori Preparata, Radix Rehmanniae Preparata, the Fructus Kochiae, Fructus Xanthii, Cortex Dictamni, Radix Glycyrrhizae cold water soak 10-30 minute is got, then put into decocting machine and decoct with water twice, first time adds above-mentioned raw material weight and 6-10 soak by water 1-2 hour doubly, second time adds above-mentioned raw materials weight and 5-8 soak by water 1-2 hour doubly, collecting decoction, filters, and collects filtrate, obtain filtrate, for subsequent use;
(3) admixing medical solutions is obtained by putting into high speed centrifuge centrifugalize under rotating speed is 10000-30000r/min after gained filtrate mixing in gained filtrate in step (1) and step (2), then the ethanol of 60-90% is added by volume, leave standstill 24-48 hour, filter, filtrate recycling ethanol, refilter, obtain admixing medical solutions, for subsequent use;
(4) gained admixing medical solutions in step (3) is put into ultrafilter to filter, the average pore size scope of the filter membrane of described ultrafilter is 20-500nm, and the pressure limit crossed in filter fly is 0.05-0.7MPa, and the scope of the crossflow velocity in filter process is 1-6m/s, obtain filtrate, for subsequent use;
(5) gained filtrate in step (4) is sent into receiver, in receiver, be evaporated to the extractum of relative density 1.10-1.15 during 60-70 DEG C, obtain extractum, for subsequent use;
(6) by gained clear paste in step (5) by sodium hydroxide solution adjust ph to 6.0-8.0, embedding is in clean vial again, steam sterilization 25-35min sterilizing under 100-103 DEG C of condition after lid is rolled in fill, and warehouse-in is finished product, must treat the Chinese medicine oral liquid of allergic dermatitis.
Preferably, a kind of preparation method for the treatment of the Chinese medicine oral liquid of allergic dermatitis, is prepared from by following methods:
(1) raw material Semen Sesami Nigrum, Flos Carthami, Flos Rosae Rugosae, Radix Arnebiae (Radix Lithospermi) cold water soak 10 minutes is got, then put into decocting machine and decoct with water twice, first time adds the soak by water 1 hour of above-mentioned raw material weight and 10 times, second time adds the soak by water 1 hour of above-mentioned raw materials weight and 8 times, collecting decoction, filters, and collects filtrate, obtain filtrate, for subsequent use;
(2) raw material Herba Schizonepetae, Caulis Spatholobi, Semen Coicis, Periostracum Cicadae, Zaocys, Radix Polygoni Multiflori Preparata, Radix Rehmanniae Preparata, the Fructus Kochiae, Fructus Xanthii, Cortex Dictamni, Radix Glycyrrhizae cold water soak 10 minutes is got, then put into decocting machine and decoct with water twice, first time adds the soak by water 1 hour of above-mentioned raw material weight and 10 times, second time adds the soak by water 1 hour of above-mentioned raw materials weight and 8 times, collecting decoction, filters, and collects filtrate, obtain filtrate, for subsequent use;
(3) admixing medical solutions is obtained by putting into high speed centrifuge centrifugalize under rotating speed is 18000r/min after gained filtrate mixing in gained filtrate in step (1) and step (2), then the ethanol of 80% is added by volume, leave standstill 48 hours, filter, filtrate recycling ethanol, refilter, obtain admixing medical solutions, for subsequent use;
(4) gained admixing medical solutions in step (3) is put into ultrafilter to filter, the average pore size of the filter membrane of described ultrafilter is 40nm, and the pressure limit crossed in filter fly is 0.3MPa, and the scope of the crossflow velocity in filter process is 3.5m/s, obtain filtrate, for subsequent use;
(5) gained filtrate in step (4) is sent into receiver, when being evaporated to 60 DEG C in receiver, the extractum of relative density 1.10, obtains extractum, for subsequent use;
(6) by gained clear paste sodium hydroxide solution adjust ph to 7.0 in step (5), embedding is in clean vial again, steam sterilization 35min sterilizing under 100 DEG C of conditions after lid is rolled in fill, and warehouse-in is finished product, must treat the Chinese medicine oral liquid of allergic dermatitis.
Beneficial effect: the present invention has effect of dispelling wind for relieving itching, clearing away heat-damp and promoting diuresis, detoxicating, killing bacteria, be a kind of safe and reliable, without any side effects, effective ingredient utilization rate is high, the Chinese medicine composition of instant effect.
The present invention adopts pure Chinese medicine to be raw material, according to pathogenic factor and the Clinical symptoms of allergic dermatitis, under instruction of Chinese Medicine theory, carry out prescription be prepared from the basis not being raw-material activity, show through clinical efficacy, this medicine has definite curative effect to allergic dermatitis, is the ideal treatment medication of a kind of allergic dermatitis patient.
Model case
Case 1: Miss Wu, 31 years old, medical history: treatment long erythema on the face, and have pruritus, 2 years, western medical treatment, drug withdrawal is recurred again, now turns Chinese traditional treatment, takes 1 course for the treatment of of Chinese medicine oral liquid of the present invention, scratchiness alleviates, erythema, pimple reduce, and continue to take 3 courses for the treatment of, symptom disappears completely, cure completely, so far without recurrence.
Case 2: Mrs Dong, 23 years old, medical history: patient main suit suffers from allergic dermatitis 2 years, and erythema, pimple increase the weight of on the face recently, takes 1 course for the treatment of of Chinese medicine oral liquid of the present invention, scratchiness alleviates, erythema, pimple reduce, and continue to take 3 courses for the treatment of, symptom disappears completely, cure completely, follow up a case by regular visits to 1 year without recurrence.
Case 3: Mr. Cao, 35 years old, medical history: large stretch of red rash on the face, pruritus, nearly erythema, pimple on the face increase the weight of, and take 1 course for the treatment of of Chinese medicine oral liquid of the present invention, scratchiness alleviates, and erythema, pimple reduce, continue to take 3 courses for the treatment of, symptom disappears completely, cures completely, follows up a case by regular visits to 1 year without recurrence.
Case 4: Mrs He, 50 years old, medical history: patient skin is easily irritated, whenever running into irritated thing, skin with regard to Pruritus, swelling unbearably, take 1 course for the treatment of of Chinese medicine oral liquid of the present invention, scratchiness alleviates, and erythema, pimple reduce, continue to take 3 courses for the treatment of, symptom disappears completely, cures completely, follows up a case by regular visits to 1 year without recurrence.
Case 5: Mr. Liu, 27 years old, medical history: skin is easily irritated, around the eye socket of face, around the bridge of the nose, all there is large area red rash, very itch, diagnosis: allergic dermatitis, takes 1 course for the treatment of of Chinese medicine oral liquid of the present invention, scratchiness alleviates, erythema, pimple reduce, and continue to take 3 courses for the treatment of, symptom disappears completely, cure completely, follow up a case by regular visits to 1 year without recurrence.
Case 6: Mrs Qu, 55 years old, medical history: patient's large stretch of red rash on the face, pruritus, scratching causes wound infection to be suppurated, take 1 course for the treatment of of Chinese medicine oral liquid of the present invention, scratchiness alleviates, and erythema, pimple reduce, continue to take 3 courses for the treatment of, symptom disappears completely, cures completely, follows up a case by regular visits to 1 year without recurrence.
Clinical data
General data: this Chinese medicine composition is applied to clinical observation case 50 example, man 30 example, female 20 example, age 16-63 year.
Diagnosis basis: (1) immunoenzyme technics phase erythra be more common in face and extremity stretch side or elbow and the moon state's nest, in erythema, pimple and the pleomorphism infringement such as to ooze out; (2) the infringement of young and adult is often for limbs bend side or stretch the lichenification erythra of side, in chronic recurrent process; Individual or family in Atopic history, such as: asthma, allergic rhinitis, atopic dermatitis; (4) acute pruritus; (5) lab testing can have eosinophil leucocyte to increase, and SERUM IgE raises.
Therapeutic Method: take oral liquid of the present invention, every day 2 times, each 30ml one week is a course for the treatment of, prohibits eat raw, hot and cold, to stimulate stomach food at period in a medicine.
Curative effect determinate standard: (1) fully recovers: skin lesion all disappears, gargalesthesia disappears; (2) effective: skin lesion and gargalesthesia disappear more than 80%; (3) effective: skin lesion and gargalesthesia disappear 50%; (4) invalid: skin lesion and gargalesthesia all do not go down.
Therapeutic effect: by this side treatment allergic dermatitis patient 50 example, wherein clinical recovery 40 example, effective 9 examples, effective 1 example, invalid 0 example, total effective rate is 100%.
Detailed description of the invention
Embodiment 1
The present invention treats the preparation of allergic dermatitis Chinese medicine oral liquid, and the weight portion of each raw material is: Herba Schizonepetae 14 parts, Caulis Spatholobi 32 parts, Semen Coicis 42 parts, Periostracum Cicadae 17 parts, Semen Sesami Nigrum 32 parts, 12 parts, Flos Carthami, Zaocys 17 parts, Radix Polygoni Multiflori Preparata 22 parts, Radix Rehmanniae Preparata 17 parts, the Fructus Kochiae 32 parts, Radix Arnebiae (Radix Lithospermi) 22 parts, Fructus Xanthii 12 parts, Cortex Dictamni 27 parts, Flos Rosae Rugosae 22 parts, 8 parts, Radix Glycyrrhizae;
Be prepared from by following methods:
(1) raw material Semen Sesami Nigrum, Flos Carthami, Flos Rosae Rugosae, Radix Arnebiae (Radix Lithospermi) cold water soak 10-30 minute is got, then put into decocting machine and decoct with water twice, first time adds above-mentioned raw material weight and 6-10 soak by water 1-2 hour doubly, second time adds above-mentioned raw materials weight and 5-8 soak by water 1-2 hour doubly, collecting decoction, filters, and collects filtrate, obtain filtrate, for subsequent use;
(2) raw material Herba Schizonepetae, Caulis Spatholobi, Semen Coicis, Periostracum Cicadae, Zaocys, Radix Polygoni Multiflori Preparata, Radix Rehmanniae Preparata, the Fructus Kochiae, Fructus Xanthii, Cortex Dictamni, Radix Glycyrrhizae cold water soak 10-30 minute is got, then put into decocting machine and decoct with water twice, first time adds above-mentioned raw material weight and 6-10 soak by water 1-2 hour doubly, second time adds above-mentioned raw materials weight and 5-8 soak by water 1-2 hour doubly, collecting decoction, filters, and collects filtrate, obtain filtrate, for subsequent use;
(3) admixing medical solutions is obtained by putting into high speed centrifuge centrifugalize under rotating speed is 10000-30000r/min after gained filtrate mixing in gained filtrate in step (1) and step (2), then the ethanol of 60-90% is added by volume, leave standstill 24-48 hour, filter, filtrate recycling ethanol, refilter, obtain admixing medical solutions, for subsequent use;
(4) gained admixing medical solutions in step (3) is put into ultrafilter to filter, the average pore size scope of the filter membrane of described ultrafilter is 20-500nm, and the pressure limit crossed in filter fly is 0.05-0.7MPa, and the scope of the crossflow velocity in filter process is 1-6m/s, obtain filtrate, for subsequent use;
(5) gained filtrate in step (4) is sent into receiver, in receiver, be evaporated to the extractum of relative density 1.10-1.15 during 60-70 DEG C, obtain extractum, for subsequent use;
(6) by gained clear paste in step (5) by sodium hydroxide solution adjust ph to 6.0-8.0, embedding is in clean vial again, steam sterilization 25-35min sterilizing under 100-103 DEG C of condition after lid is rolled in fill, and warehouse-in is finished product, must treat the Chinese medicine oral liquid of allergic dermatitis.
Usage: oral, every day 2 times, each 30ml.
Embodiment 2
The present invention treats the preparation of allergic dermatitis Chinese medicine oral liquid, and the weight portion of each raw material is: Herba Schizonepetae 12 parts, Caulis Spatholobi 30 parts, Semen Coicis 40 parts, Periostracum Cicadae 15 parts, Semen Sesami Nigrum 30 parts, 10 parts, Flos Carthami, Zaocys 15 parts, Radix Polygoni Multiflori Preparata 20 parts, Radix Rehmanniae Preparata 15 parts, the Fructus Kochiae 30 parts, Radix Arnebiae (Radix Lithospermi) 20 parts, Fructus Xanthii 10 parts, Cortex Dictamni 25 parts, Flos Rosae Rugosae 20 parts, 6 parts, Radix Glycyrrhizae;
Be prepared from by following methods:
(1) raw material Semen Sesami Nigrum, Flos Carthami, Flos Rosae Rugosae, Radix Arnebiae (Radix Lithospermi) cold water soak 10-30 minute is got, then put into decocting machine and decoct with water twice, first time adds above-mentioned raw material weight and 6-10 soak by water 1-2 hour doubly, second time adds above-mentioned raw materials weight and 5-8 soak by water 1-2 hour doubly, collecting decoction, filters, and collects filtrate, obtain filtrate, for subsequent use;
(2) raw material Herba Schizonepetae, Caulis Spatholobi, Semen Coicis, Periostracum Cicadae, Zaocys, Radix Polygoni Multiflori Preparata, Radix Rehmanniae Preparata, the Fructus Kochiae, Fructus Xanthii, Cortex Dictamni, Radix Glycyrrhizae cold water soak 10-30 minute is got, then put into decocting machine and decoct with water twice, first time adds above-mentioned raw material weight and 6-10 soak by water 1-2 hour doubly, second time adds above-mentioned raw materials weight and 5-8 soak by water 1-2 hour doubly, collecting decoction, filters, and collects filtrate, obtain filtrate, for subsequent use;
(3) admixing medical solutions is obtained by putting into high speed centrifuge centrifugalize under rotating speed is 10000-30000r/min after gained filtrate mixing in gained filtrate in step (1) and step (2), then the ethanol of 60-90% is added by volume, leave standstill 24-48 hour, filter, filtrate recycling ethanol, refilter, obtain admixing medical solutions, for subsequent use;
(4) gained admixing medical solutions in step (3) is put into ultrafilter to filter, the average pore size scope of the filter membrane of described ultrafilter is 20-500nm, and the pressure limit crossed in filter fly is 0.05-0.7MPa, and the scope of the crossflow velocity in filter process is 1-6m/s, obtain filtrate, for subsequent use;
(5) gained filtrate in step (4) is sent into receiver, in receiver, be evaporated to the extractum of relative density 1.10-1.15 during 60-70 DEG C, obtain extractum, for subsequent use;
(6) by gained clear paste in step (5) by sodium hydroxide solution adjust ph to 6.0-8.0, embedding is in clean vial again, steam sterilization 25-35min sterilizing under 100-103 DEG C of condition after lid is rolled in fill, and warehouse-in is finished product, must treat the Chinese medicine oral liquid of allergic dermatitis.
Usage: oral, every day 2 times, each 30ml.
Embodiment 3
The present invention treats the preparation of allergic dermatitis Chinese medicine oral liquid, and the weight portion of each raw material is: Herba Schizonepetae 10 parts, Caulis Spatholobi 28 parts, Semen Coicis 38 parts, Periostracum Cicadae 13 parts, Semen Sesami Nigrum 28 parts, 8 parts, Flos Carthami, Zaocys 13 parts, Radix Polygoni Multiflori Preparata 18 parts, Radix Rehmanniae Preparata 13 parts, the Fructus Kochiae 28 parts, Radix Arnebiae (Radix Lithospermi) 18 parts, Fructus Xanthii 8 parts, Cortex Dictamni 23 parts, Flos Rosae Rugosae 18 parts, 4 parts, Radix Glycyrrhizae;
Be prepared from by following methods:
(1) raw material Semen Sesami Nigrum, Flos Carthami, Flos Rosae Rugosae, Radix Arnebiae (Radix Lithospermi) cold water soak 10-30 minute is got, then put into decocting machine and decoct with water twice, first time adds above-mentioned raw material weight and 6-10 soak by water 1-2 hour doubly, second time adds above-mentioned raw materials weight and 5-8 soak by water 1-2 hour doubly, collecting decoction, filters, and collects filtrate, obtain filtrate, for subsequent use;
(2) raw material Herba Schizonepetae, Caulis Spatholobi, Semen Coicis, Periostracum Cicadae, Zaocys, Radix Polygoni Multiflori Preparata, Radix Rehmanniae Preparata, the Fructus Kochiae, Fructus Xanthii, Cortex Dictamni, Radix Glycyrrhizae cold water soak 10-30 minute is got, then put into decocting machine and decoct with water twice, first time adds above-mentioned raw material weight and 6-10 soak by water 1-2 hour doubly, second time adds above-mentioned raw materials weight and 5-8 soak by water 1-2 hour doubly, collecting decoction, filters, and collects filtrate, obtain filtrate, for subsequent use;
(3) admixing medical solutions is obtained by putting into high speed centrifuge centrifugalize under rotating speed is 10000-30000r/min after gained filtrate mixing in gained filtrate in step (1) and step (2), then the ethanol of 60-90% is added by volume, leave standstill 24-48 hour, filter, filtrate recycling ethanol, refilter, obtain admixing medical solutions, for subsequent use;
(4) gained admixing medical solutions in step (3) is put into ultrafilter to filter, the average pore size scope of the filter membrane of described ultrafilter is 20-500nm, and the pressure limit crossed in filter fly is 0.05-0.7MPa, and the scope of the crossflow velocity in filter process is 1-6m/s, obtain filtrate, for subsequent use;
(5) gained filtrate in step (4) is sent into receiver, in receiver, be evaporated to the extractum of relative density 1.10-1.15 during 60-70 DEG C, obtain extractum, for subsequent use;
(6) by gained clear paste in step (5) by sodium hydroxide solution adjust ph to 6.0-8.0, embedding is in clean vial again, steam sterilization 25-35min sterilizing under 100-103 DEG C of condition after lid is rolled in fill, and warehouse-in is finished product, must treat the Chinese medicine oral liquid of allergic dermatitis.
Usage: oral, every day 2 times, each 30ml.
Claims (6)
1. treat a Chinese medicine oral liquid for allergic dermatitis, it is characterized in that: be made up of following raw material: Herba Schizonepetae 10-14 part, Caulis Spatholobi 28-32 part, Semen Coicis 38-42 part, Periostracum Cicadae 13-17 part, Semen Sesami Nigrum 28-32 part, Flos Carthami 8-12 part, Zaocys 13-17 part, Radix Polygoni Multiflori Preparata 18-22 part, Radix Rehmanniae Preparata 13-17 part, Fructus Kochiae 28-32 part, Radix Arnebiae (Radix Lithospermi) 18-22 part, Fructus Xanthii 8-12 part, Cortex Dictamni 23-27 part, Flos Rosae Rugosae 18-22 part, Radix Glycyrrhizae 4-8 part.
2. a kind of Chinese medicine oral liquid for the treatment of allergic dermatitis according to claim 1, is characterized in that: the weight portion of each raw material is: Herba Schizonepetae 12 parts, Caulis Spatholobi 30 parts, Semen Coicis 40 parts, Periostracum Cicadae 15 parts, Semen Sesami Nigrum 30 parts, 10 parts, Flos Carthami, Zaocys 15 parts, Radix Polygoni Multiflori Preparata 20 parts, Radix Rehmanniae Preparata 15 parts, the Fructus Kochiae 30 parts, Radix Arnebiae (Radix Lithospermi) 20 parts, Fructus Xanthii 10 parts, Cortex Dictamni 25 parts, Flos Rosae Rugosae 20 parts, 6 parts, Radix Glycyrrhizae.
3. a kind of Chinese medicine oral liquid for the treatment of allergic dermatitis according to claim 1, is characterized in that: the weight portion of each raw material is: Herba Schizonepetae 14 parts, Caulis Spatholobi 32 parts, Semen Coicis 42 parts, Periostracum Cicadae 17 parts, Semen Sesami Nigrum 32 parts, 12 parts, Flos Carthami, Zaocys 17 parts, Radix Polygoni Multiflori Preparata 22 parts, Radix Rehmanniae Preparata 17 parts, the Fructus Kochiae 32 parts, Radix Arnebiae (Radix Lithospermi) 22 parts, Fructus Xanthii 12 parts, Cortex Dictamni 27 parts, Flos Rosae Rugosae 22 parts, 8 parts, Radix Glycyrrhizae.
4. a kind of Chinese medicine oral liquid for the treatment of allergic dermatitis according to claim 1, is characterized in that: the weight portion of each raw material is: Herba Schizonepetae 10 parts, Caulis Spatholobi 28 parts, Semen Coicis 38 parts, Periostracum Cicadae 13 parts, Semen Sesami Nigrum 28 parts, 8 parts, Flos Carthami, Zaocys 13 parts, Radix Polygoni Multiflori Preparata 18 parts, Radix Rehmanniae Preparata 13 parts, the Fructus Kochiae 28 parts, Radix Arnebiae (Radix Lithospermi) 18 parts, Fructus Xanthii 8 parts, Cortex Dictamni 23 parts, Flos Rosae Rugosae 18 parts, 4 parts, Radix Glycyrrhizae.
5. a kind of preparation method for the treatment of the Chinese medicine oral liquid of allergic dermatitis according to claim 1 and 2, is characterized in that: be prepared from by following methods:
(1) raw material Semen Sesami Nigrum, Flos Carthami, Flos Rosae Rugosae, Radix Arnebiae (Radix Lithospermi) cold water soak 10-30 minute is got, then put into decocting machine and decoct with water twice, first time adds above-mentioned raw material weight and 6-10 soak by water 1-2 hour doubly, second time adds above-mentioned raw materials weight and 5-8 soak by water 1-2 hour doubly, collecting decoction, filters, and collects filtrate, obtain filtrate, for subsequent use;
(2) raw material Herba Schizonepetae, Caulis Spatholobi, Semen Coicis, Periostracum Cicadae, Zaocys, Radix Polygoni Multiflori Preparata, Radix Rehmanniae Preparata, the Fructus Kochiae, Fructus Xanthii, Cortex Dictamni, Radix Glycyrrhizae cold water soak 10-30 minute is got, then put into decocting machine and decoct with water twice, first time adds above-mentioned raw material weight and 6-10 soak by water 1-2 hour doubly, second time adds above-mentioned raw materials weight and 5-8 soak by water 1-2 hour doubly, collecting decoction, filters, and collects filtrate, obtain filtrate, for subsequent use;
(3) admixing medical solutions is obtained by putting into high speed centrifuge centrifugalize under rotating speed is 10000-30000r/min after gained filtrate mixing in gained filtrate in step (1) and step (2), then the ethanol of 60-90% is added by volume, leave standstill 24-48 hour, filter, filtrate recycling ethanol, refilter, obtain admixing medical solutions, for subsequent use;
(4) gained admixing medical solutions in step (3) is put into ultrafilter to filter, the average pore size scope of the filter membrane of described ultrafilter is 20-500nm, and the pressure limit crossed in filter fly is 0.05-0.7MPa, and the scope of the crossflow velocity in filter process is 1-6m/s, obtain filtrate, for subsequent use;
(5) gained filtrate in step (4) is sent into receiver, in receiver, be evaporated to the extractum of relative density 1.10-1.15 during 60-70 DEG C, obtain extractum, for subsequent use;
(6) by gained clear paste in step (5) by sodium hydroxide solution adjust ph to 6.0-8.0, embedding is in clean vial again, steam sterilization 25-35min sterilizing under 100-103 DEG C of condition after lid is rolled in fill, and warehouse-in is finished product, must treat the Chinese medicine oral liquid of allergic dermatitis.
6. a kind of preparation method for the treatment of the Chinese medicine oral liquid of allergic dermatitis according to claim 1 and 2, is characterized in that: be prepared from by following methods:
(1) raw material Semen Sesami Nigrum, Flos Carthami, Flos Rosae Rugosae, Radix Arnebiae (Radix Lithospermi) cold water soak 10 minutes is got, then put into decocting machine and decoct with water twice, first time adds the soak by water 1 hour of above-mentioned raw material weight and 10 times, second time adds the soak by water 1 hour of above-mentioned raw materials weight and 8 times, collecting decoction, filters, and collects filtrate, obtain filtrate, for subsequent use;
(2) raw material Herba Schizonepetae, Caulis Spatholobi, Semen Coicis, Periostracum Cicadae, Zaocys, Radix Polygoni Multiflori Preparata, Radix Rehmanniae Preparata, the Fructus Kochiae, Fructus Xanthii, Cortex Dictamni, Radix Glycyrrhizae cold water soak 10 minutes is got, then put into decocting machine and decoct with water twice, first time adds the soak by water 1 hour of above-mentioned raw material weight and 10 times, second time adds the soak by water 1 hour of above-mentioned raw materials weight and 8 times, collecting decoction, filters, and collects filtrate, obtain filtrate, for subsequent use;
(3) admixing medical solutions is obtained by putting into high speed centrifuge centrifugalize under rotating speed is 18000r/min after gained filtrate mixing in gained filtrate in step (1) and step (2), then the ethanol of 80% is added by volume, leave standstill 48 hours, filter, filtrate recycling ethanol, refilter, obtain admixing medical solutions, for subsequent use;
(4) gained admixing medical solutions in step (3) is put into ultrafilter to filter, the average pore size of the filter membrane of described ultrafilter is 40nm, and the pressure limit crossed in filter fly is 0.3MPa, and the scope of the crossflow velocity in filter process is 3.5m/s, obtain filtrate, for subsequent use;
(5) gained filtrate in step (4) is sent into receiver, when being evaporated to 60 DEG C in receiver, the extractum of relative density 1.10, obtains extractum, for subsequent use;
(6) by gained clear paste sodium hydroxide solution adjust ph to 7.0 in step (5), embedding is in clean vial again, steam sterilization 35min sterilizing under 100 DEG C of conditions after lid is rolled in fill, and warehouse-in is finished product, must treat the Chinese medicine oral liquid of allergic dermatitis.
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1316268A (en) * | 2001-03-08 | 2001-10-10 | 刁金山 | Qufengbaidu pill for treating skin itchings |
| CN1343506A (en) * | 2000-09-15 | 2002-04-10 | 海国灿 | Chinese patent medicine for treating allergic dermatopathy |
| CN103830632A (en) * | 2014-03-26 | 2014-06-04 | 刘洪� | Chinese traditional medicine preparation for radically treating psoriasis and multiple skin diseases and preparation method and application thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1343506A (en) * | 2000-09-15 | 2002-04-10 | 海国灿 | Chinese patent medicine for treating allergic dermatopathy |
| CN1316268A (en) * | 2001-03-08 | 2001-10-10 | 刁金山 | Qufengbaidu pill for treating skin itchings |
| CN103830632A (en) * | 2014-03-26 | 2014-06-04 | 刘洪� | Chinese traditional medicine preparation for radically treating psoriasis and multiple skin diseases and preparation method and application thereof |
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| 凌沛学: "《中药学概论》", 31 August 2007, 中国轻工业出版社 * |
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