CN103830632A - Chinese traditional medicine preparation for radically treating psoriasis and multiple skin diseases and preparation method and application thereof - Google Patents
Chinese traditional medicine preparation for radically treating psoriasis and multiple skin diseases and preparation method and application thereof Download PDFInfo
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- CN103830632A CN103830632A CN201410114439.7A CN201410114439A CN103830632A CN 103830632 A CN103830632 A CN 103830632A CN 201410114439 A CN201410114439 A CN 201410114439A CN 103830632 A CN103830632 A CN 103830632A
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Abstract
The invention provides a pure Chinese traditional medicine preparation for treating psoriasis and multiple skin diseases. The pure Chinese traditional medicine preparation is prepared from the following 21 Chinese traditional medicinal materials: honeysuckle flowers, cortex phellodendri chinensis, flos chrysanthemi indici, glabrous greenbrier rhizome, common ducksmeat herb, yam rhizome, radix rehmanniae, zaocys dhumnade and the like. The pure Chinese traditional medicine preparation provided by the invention has the effects of dispelling wind and nourishing blood, removing dampness to relieve itching, removing pathogenic heat from the blood and toxic materials from the body and supporting the healthy energy, has good treatment effects on the allergic reaction, epidermis proliferation cornification, lichenification, vascular inflammation and hair follicle and sebaceous gland blockage, such as the psoriasis (psora), leucoderma, neurodermatitis, dermatitis, eczema, urticaria, irritability, rubella, comedo, acne and verruca plana, is wide in clinical application treatment range without toxic and side effects, and can not injure the organs and functions of a human body and enhance the physique and the immunity of the human body even if being taken for a long time. A medicament prepared through a preparation method of the pure Chinese traditional medicine preparation is high in dissolution rate and higher in stability.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation and preparation thereof and application, be specifically related to a kind of Chinese medicine preparation that effects a radical cure the multiple dermatosis such as psoriasis and preparation method thereof and application.
Background technology
According to incompletely statistics, China has more than 400 ten thousand people to suffer from psoriasis at present, and nearly hundred million people suffered from dermatosis, and this some patients were is being waited for effectively treatment of acceptance.Although the psoriatic medicine of western medicine is a lot, because the psoriatic course of disease is long, be difficult to cure, need long-term taking medicine, this is just to gastrointestinal tract, liver, kidney and hematopoietic function are impaired, thereby cause Other diseases, have brought again new suffering of illness and worry to patient! Exploitation therapeutic effect is good and the medicine that has no side effect is numerous psoriatics' urgent needs!
Probe into from pathogeny, have many inducements: inherited genetic factors, environmental factors and Nervous and Mental Factors etc., cause immunologic hypofunction, dysbolismus, endocrine disturbance, living environments etc. are relevant.The traditional Chinese medical science is thought, internal injury caused by excess of seven emotions can make feelings will not relax, and upsets equilibrium between yin and yang, visceral dysfunction, and skin sense ailment said due to cold or exposure, in noxious dampness enters, can not get conditioning for a long time, causes psoriatic feature.
Treatment aim of the present invention is strengthening the body resistance, regulates immunologic function, and nourishing blood to suppress the hyperactive liver regulates taste, has dispelling wind to nourish blood, removing damp to relieve itching, and effect of removing pathogenic heat from blood and toxic substance from the body, outer sick treatment by oral administration of medicines, has overcome the psoriatic many drawbacks of western medical treatment for many years.
Summary of the invention
The invention provides a kind of psoriasis and other multiple dermatosis, long-term taking of effecting a radical cure to human internal organ not damaged and the newtype drug having no side effect and application thereof.
The present invention provides the preparation method of this therapeutic agent simultaneously
Technical scheme of the present invention is as follows:
The consumption of drug component of the present invention, is to grope in a large number clinical summary through inventor to draw, each amounts of components for there being good curative effect within the scope of following weight parts:
Flos Lonicerae 20-100, Cortex Phellodendri 10-80, Rhizoma Dioscoreae Septemlobae 10-70, Herba Spirodelae 15-70, Flos Chrysanthemi Indici 10-80, Radix Arnebiae (Radix Lithospermi) 10-60, Cortex Moutan 10-60, Radix Saposhnikoviae 15-70, Rhizoma Smilacis Glabrae 10-70, Fructus Kochiae 10-90, Fructus Forsythiae 15-80, Radix Salviae Miltiorrhizae 15-200, Radix Glycyrrhizae 6-300, Radix Rehmanniae 20-200, Placenta Hominis 20-200, Semen Persicae 15-80, Zaocys 6-70, favus skin 15-60, Caulis Spatholobi 15-100, Herba Schizonepetae 15-80, Herba Hedyotidis Diffusae 20-200.
Weight (part) ratio range of the formula optimization of preparation medicine of the present invention is:
Flos Lonicerae 40-80, Cortex Phellodendri 20-70, Rhizoma Dioscoreae Septemlobae 20-60, Herba Spirodelae 30-50, Flos Chrysanthemi Indici 20-60, Radix Arnebiae (Radix Lithospermi) 20-50, Cortex Moutan 20-50, Radix Saposhnikoviae 30-65, Rhizoma Smilacis Glabrae 20-50, Fructus Kochiae 20-70, Fructus Forsythiae 30-60, Radix Salviae Miltiorrhizae 30-160, Radix Glycyrrhizae 20-100, Radix Rehmanniae 40-160, Placenta Hominis 40-160, Semen Persicae 30-50, Zaocys 15-60, favus skin 30-50, Caulis Spatholobi 30-70, Herba Schizonepetae 30-50, Herba Hedyotidis Diffusae 40-160.
Optimum weight (part) proportioning of preparation medicine of the present invention is:
Flos Lonicerae 80, Cortex Phellodendri 50, Rhizoma Dioscoreae Septemlobae 40, Herba Spirodelae 30, Flos Chrysanthemi Indici 50, Radix Arnebiae (Radix Lithospermi) 40, Cortex Moutan 40, Radix Saposhnikoviae 50, Rhizoma Smilacis Glabrae 40, the Fructus Kochiae 50, Fructus Forsythiae 45, Radix Salviae Miltiorrhizae 110, Radix Glycyrrhizae 60, the Radix Rehmanniae 120, Placenta Hominis 110, Semen Persicae 40, Zaocys 30, favus skin 45, Caulis Spatholobi 50, Herba Schizonepetae 30, Herba Hedyotidis Diffusae 70.
Above-mentioned formula of the present invention and acceptable adjuvant medically, can be made into the dosage form on any pharmaceuticss such as capsule, granule, powder, pill or oral liquid.
Preferably, the preparation method of active constituents of medicine of the present invention comprises the steps:
(1), that Flos Lonicerae, Cortex Phellodendri, Flos Chrysanthemi Indici, Rhizoma Smilacis Glabrae, Herba Spirodelae, Rhizoma Dioscoreae Septemlobae, Placenta Hominis, Zaocys, the Radix Rehmanniae, Radix Arnebiae (Radix Lithospermi), the Fructus Kochiae, favus skin, Cortex Moutan, Semen Persicae, Caulis Spatholobi, Herba Schizonepetae, Radix Saposhnikoviae, Fructus Forsythiae, Radix Salviae Miltiorrhizae, Radix Glycyrrhizae, Herba Hedyotidis Diffusae 20 Herba indigoferae Pseudotinctoriae is for subsequent use after choosing medicine, washing, oven dry;
(2), take above-mentioned 20 Herba indigoferae Pseudotinctoriae by required weight proportion, shred, concoct in rearmounted extractor, add water, decoct 2 times, each amount of water was not to have powder to be advisable;
(3), merge the liquid of boiling medicine, filtration, be condensed into the clear paste that relative density is 1.0-1.15;
(4), be chilled to after room temperature until above-mentioned clear paste, add 1-2 doubly 95% ethanol carry out precipitate with ethanol;
(5), go upper strata filtrate, reclaim ethanol, and then the concentrated relative density thick paste that is 1.25-1.33;
(6), get above-mentioned thick paste, add medically acceptable adjuvant, make various dosage forms.
In above-mentioned preparation method, the preferred version of each step is: (1), by Flos Lonicerae, Cortex Phellodendri, Flos Chrysanthemi Indici, Rhizoma Smilacis Glabrae, Herba Spirodelae, Rhizoma Dioscoreae Septemlobae, Placenta Hominis, Zaocys, the Radix Rehmanniae, Radix Arnebiae (Radix Lithospermi), the Fructus Kochiae, favus skin, Cortex Moutan, Semen Persicae, Caulis Spatholobi, Herba Schizonepetae, Radix Saposhnikoviae, Fructus Forsythiae, Radix Salviae Miltiorrhizae, Radix Glycyrrhizae, Herba Hedyotidis Diffusae 20 Herba indigoferae Pseudotinctoriae, each is for subsequent use after concocting (very important) through choosing medicine, washing, oven dry; (2) by required weight proportion take above-mentioned 20 simply medicine be placed in extractor: decoct with water 2 times; Decoct for the first time institute's amount of water and be 8 times of raw material weight, soak and within 1 hour, decoct 1-2 hour; Decocting is for the second time to add water 6 times to measure, and soaks 1 hour, decocts 1-2 hour, and (3) collecting decoction filtration, is at 70-80 ℃, is concentrated to relative density and is 1.07 clear paste; (4) be chilled to after room temperature until above-mentioned clear paste, adding ethanol to make containing alcohol amount is 65%, leaves standstill and within 24-36 hour, carries out precipitate with ethanol; (5) take out upper strata filtrate, the form sediment ethanol of precipitate 50-60% of gained of alcohol is fully washed to the filtrate merging of cleaning mixture and precipitate with ethanol gained; By the decompression filtrate recycling ethanol after merging, and be condensed into the thick paste of 1.25-1.33.(6) get above-mentioned thick paste, add medically acceptable adjuvant, make various dosage forms.
The active component of medicine of the present invention can add the various adjuvants while preparing different dosage form, as conventional method of Chinese medicinal such as disintegrating agent, lubricant, binding agents, is prepared into any dosage form, as capsule, granule, powder, pill or oral liquid etc.
In preparation method of the present invention, in preferred steps (6), by the thick paste making, add cane sugar powder, dextrin soft material processed, oven dry adds appropriate wetting agent after pulverizing, and granulates, dry.More preferably: the clear paste portion of obtaining, 1.8 parts of cane sugar powders, 2.1 parts of soft materials processed of dextrin, oven dry adds ethanol after pulverizing, and cross 14 mesh sieves and granulate, 65 ℃ of oven dry, granulate, sieves, subpackage.
Medicament selection Flos Lonicerae of the present invention, Flos Chrysanthemi Indici, Cortex Phellodendri, pathogenic fire reducing removing toxic substances, the Radix Rehmanniae, Semen Persicae, the refrigerant blood of Radix Arnebiae (Radix Lithospermi), hemopoietic, nourshing Yin and drynsessmoistening prescription, Rhizoma Smilacis Glabrae, Herba Spirodelae, Rhizoma Dioscoreae Septemlobae clearing away heat-damp and promoting diuresis, Placenta Hominis, Herba Hedyotidis Diffusae are supported flesh and consolidate, Zaocys, the Fructus Kochiae, favus skin, Cortex Moutan, wind-repellent itching-relieving, through focus, Caulis Spatholobi, Radix Salviae Miltiorrhizae blood circulation promoting and blood stasis dispelling, skin moistening toxin expelling, Herba Schizonepetae, Radix Saposhnikoviae, Fructus Forsythiae dispel the wind disappear heresy, strengthen body resistance and relieve exterior syndrome, the removing toxic substances of Radix Glycyrrhizae, stomach function regulating, adjust property of traditional Chinese.By these drug regimens, make each efficacy of drugs produce synergism, all medicines coordinate gather altogether removing pathogenic heat from blood and toxic substance from the body, expelling wind and removing dampness, strengthening body resistance and dispelling evil, blood circulation promoting and blood stasis dispelling, support flesh skin moistening, thereby effectively treat dermatosis.This side's primary treatment psoriasis, also can be used for treating vitiligo, eczema, dermatitis, allergy, urticaria, acne, acne, viral dermatosis etc.
The present invention applies for many years, and treatment patient thousands of examples have clinically proved unrivaled superiority.Medication effect of the present invention is good, does not recur, and takes medicine conveniently, has no side effect etc.
The specific embodiment
The preparation of medicinal granule of the present invention: embodiment writes out a prescription as follows: Flos Lonicerae 80g, Cortex Phellodendri 50g, Rhizoma Dioscoreae Septemlobae 40g, Herba Spirodelae 30g, Flos Chrysanthemi Indici 50g, Radix Arnebiae (Radix Lithospermi) 40g, Cortex Moutan 40g, Radix Saposhnikoviae 50g, Rhizoma Smilacis Glabrae 40g, Fructus Kochiae 50g, Fructus Forsythiae 45g, Radix Salviae Miltiorrhizae 110g, Radix Glycyrrhizae 60g, Radix Rehmanniae 120g, Placenta Hominis 110g, Semen Persicae 40g, Zaocys 30g, favus skin 45g, Caulis Spatholobi 50g, Herba Schizonepetae 30g, Herba Hedyotidis Diffusae 70g.
Method for making: by side 20 simply through choosing medicine, washing, after drying, weigh, the process of preparing Chinese medicine is placed in extractor, add water 8 times, invade bubble and within 1 hour, decoct 1-2 hour, decocting is for the second time the 6 times of amounts that add water, invade bubble 1 hour, decoct 1 hour, collecting decoction filters, at 70-80 ℃, be concentrated to relative density and be 1.07 clear paste, be chilled to after room temperature until above-mentioned clear paste, adding 95% ethanol to make containing alcohol amount is 65%, leave standstill and within 24-36 hour, carry out alcohol shallow lake, take out upper strata filtrate, reclaim ethanol, and be condensed into the thick paste of 1.25-1.33, get 1 part of above-mentioned thick paste, add 1.8 parts of cane sugar powders, 2.1 parts of soft materials processed of dextrin, dry to pulverize and add appropriate amount of ethanol, crossing 14 mesh sieves granulates, at 65 ℃, dry, granulate, sieve, subpackage and get final product.
Other dosage form adopts above-mentioned active substance extracting method successively, prepares the dosage forms such as tablet, decoction, capsule, powder, pill and oral liquid with conventional method of Chinese medicinal.
Different dosage form and instructions of taking:
Test example:
Data and method:
1, case inclusion criteria: (1) is agreed to enter clinically diagnosed cases through me, and the age, between 18～65 years old, meets " clinical common disease diagnosis and treatment standard ".(2) in (1), find psoriasis vulgaris diagnostic criteria, signature Informed Consent Form person.(3) not system applies glucocorticoid, immunosuppressant and immunomodulator in all patients 1 month.(4) without gestation, age of sucking and plan during treating the Women of Childbearing Age of giving birth in 2 years.(5) autoimmune disease and other serious systemic diseases such as rheumatic arthritis, without hypertension, aldosterone disease, hypokalemia, myopathy and other serious organ and systemic disease, hepatic and renal function is without abnormal person.
2, ordinary circumstance: treatment group 38 examples, male 23 examples, female's 15 examples, age 18-69 year, on average (35.63 ± 22.86) year, the course of disease is the shortest 10 days, the longest 42 years, wherein drips shape 8 examples, speckle shape 9 examples, mix shape 16 examples, erythrodermic 5 examples, matched group 30 examples, man's 12 examples, female's 18 examples, age 18-66 year, average (36.23 ± 21.84) year, the course of disease is the shortest 12 days, the longest 29 years, wherein drips shape 6 examples, speckle shape 8 examples, mix shape 12 examples, erythrodermic 4 examples.
3, Therapeutic Method: treatment group adopts granule of the present invention oral, every day 3 times, each 20g; It is oral that matched group is taken XIAOYIN PIAN, every day 3 times, each 6; Take medicine continuously and within 8 weeks, carry out therapeutic evaluation.1-3 month course for the treatment of, follow up a case by regular visits to half a year.
4, criterion: carry out PASI scoring according to the scope of patient's erythema, infiltration, squama and serious Cheng Du before and after treatment, and calculate treatment front and back PASI change percentage in arid, computational methods are as follows: PASI change percentage in arid=(total score after the front total score-treatment for the treatment of) front total score × 100% of/treatment.Percentage rate >95% is recovery from illness, and 61%-95% is effective, and 31%-60% be effectively, and percentage rate <30% is invalid, total effective rate=(base heal number of cases+effective number of cases)/always case load × 100%.During treatment, detect blood pressure and serum potassium, occur serious adverse reaction exit observe routine person be judged to invalid.The effective case of fundamental sum is followed up a case by regular visits to half a year, and PASI scoring is judged to without recurrence without increased perosn.
5, statistical procedures: to PASI scoring before and after every group for the treatment of, carry out respectively t check, two groups of total effectively number of cases for the treatment of are carried out to x
2check.
Result:
17 examples of fully recovering in treatment group 38 examples account for 44.7%, effective 13 examples, effective 5 examples, invalid 3 examples, total effective rate 92.1%.In matched group 30 examples base more 4 examples account for 13.3%, effective 9 examples, effective 6 examples, invalid 11 examples, 63.3%, two group of total effective rate difference of total effective rate has statistical significance (x
2=3.95, P<0.05).Before and after two groups of treatments, PASI diversity of values all has statistical significance, (t=2.10, p<0.05).See the following form.
Treat psoriatic effect comparison table for two groups
| Group | Number of cases | Before treatment | After treatment | T value | P value |
| Treatment group | 38 | 11.13±4.70 | 2.61±3.31 | 11.59 | <0.001 |
| Matched group | 30 | 11.28±4.70 | 4.62±4.34 | 9.13 | <0.001 |
Before and after two groups for the treatment of psoriasises, PASI scoring relatively
| Number of cases | Clinical cure | Effective | Effectively | Invalid | Clinical cure rate (%) | Total effective rate (%) |
| 38 | 17 | 13 | 5 | 3 | 44.7 | 92.1 |
| 30 | 4 | 9 | 6 | 11 | 13.3 | 63.3 |
Without exiting case, to follow up a case by regular visits to after half a year, treatment group is without recurrent cases, and matched group recurs 2 examples.
Untoward reaction: none routine untoward reaction for the treatment of group occurs.There are chronic abdominal pain 3 examples in matched group, diarrhea 2 examples, and constipation 1 example, sexual hypofunction 5 examples, transaminase's 2 examples that raise, after symptomatic treatment, make the overall process of 13 routine patient's completed treatments.
The above embodiment of the present invention is only used to clearly illustrate example of the present invention, and be not the restriction to embodiments of the present invention, for those of ordinary skill in the field, can also make on the basis of the above description other multi-form variation and variation.Here exhaustive without also giving all modes, and these belong to apparent variation or variation that spirit of the present invention is extended, still among protection scope of the present invention.
Claims (10)
1. radical cure psoriasis and a various dermopathic medicine, is characterized in that it is mainly by making with the raw material of following weight parts proportioning:
Flos Lonicerae 20-100, Cortex Phellodendri 10-80, Rhizoma Dioscoreae Septemlobae 10-70, Herba Spirodelae 15-70, Flos Chrysanthemi Indici 10-80, Radix Arnebiae (Radix Lithospermi) 10-60, Cortex Moutan 10-60, Radix Saposhnikoviae 15-70, Rhizoma Smilacis Glabrae 10-70, Fructus Kochiae 10-90, Fructus Forsythiae 15-80, Radix Salviae Miltiorrhizae 15-200, Radix Glycyrrhizae 6-300, Radix Rehmanniae 20-200, Placenta Hominis 20-200, Semen Persicae 15-80, Zaocys 6-70, favus skin 15-60, Caulis Spatholobi 15-100, Herba Schizonepetae 15-80, Herba Hedyotidis Diffusae 20-200.
2. medicine according to claim 1, wherein the weight portion proportioning of each raw material is:
Flos Lonicerae 40-80, Cortex Phellodendri 20-70, Rhizoma Dioscoreae Septemlobae 20-60, Herba Spirodelae 30-50, Flos Chrysanthemi Indici 20-60, Radix Arnebiae (Radix Lithospermi) 20-50, Cortex Moutan 20-50, Radix Saposhnikoviae 30-65, Rhizoma Smilacis Glabrae 20-50, Fructus Kochiae 20-70, Fructus Forsythiae 30-60, Radix Salviae Miltiorrhizae 30-160, Radix Glycyrrhizae 20-100, Radix Rehmanniae 40-160, Placenta Hominis 40-160, Semen Persicae 30-50, Zaocys 15-60, favus skin 30-50, Caulis Spatholobi 30-70, Herba Schizonepetae 30-50, Herba Hedyotidis Diffusae 40-160.
3. medicine according to claim 2, wherein the weight portion proportioning of each raw material is:
Flos Lonicerae 80, Cortex Phellodendri 50, Rhizoma Dioscoreae Septemlobae 40, Herba Spirodelae 30, Flos Chrysanthemi Indici 50, Radix Arnebiae (Radix Lithospermi) 40, Cortex Moutan 40, Radix Saposhnikoviae 50, Rhizoma Smilacis Glabrae 40, the Fructus Kochiae 50, Fructus Forsythiae 45, Radix Salviae Miltiorrhizae 110, Radix Glycyrrhizae 60, the Radix Rehmanniae 120, Placenta Hominis 110, Semen Persicae 40, Zaocys 30, favus skin 45, Caulis Spatholobi 50, Herba Schizonepetae 30, Herba Hedyotidis Diffusae 70.
4. according to the medicine described in claim 1,2 or 3, it is characterized in that forming the dosage form on any pharmaceutics with medically acceptable adjuvant.
5. medicine according to claim 4, it is characterized in that and medically acceptable adjuvant composition capsule, granule, powder, pill or oral liquid.
6. the preparation method of medicine according to claim 4, it comprises the following steps:
(1), that Flos Lonicerae, Cortex Phellodendri, Flos Chrysanthemi Indici, Rhizoma Smilacis Glabrae, Herba Spirodelae, Rhizoma Dioscoreae Septemlobae, Placenta Hominis, Zaocys, the Radix Rehmanniae, Radix Arnebiae (Radix Lithospermi), the Fructus Kochiae, favus skin, Cortex Moutan, Semen Persicae, Caulis Spatholobi, Herba Schizonepetae, Radix Saposhnikoviae, Fructus Forsythiae, Radix Salviae Miltiorrhizae, Radix Glycyrrhizae, Herba Hedyotidis Diffusae 20 Herba indigoferae Pseudotinctoriae is for subsequent use after choosing medicine, washing, oven dry, the process of preparing Chinese medicine;
(2), take above-mentioned 20 Herba indigoferae Pseudotinctoriae by required weight proportion, shred, put in extractor, add water, decoct 2 times;
(3), merge the liquid of boiling medicine, filtration, be condensed into the clear paste that relative density is 1.0-1.15;
(4), be chilled to after room temperature until above-mentioned clear paste, add 1-2 doubly 95% ethanol carry out precipitate with ethanol;
(5), go upper strata filtrate, reclaim ethanol, and then the concentrated relative density thick paste that is 1.25-1.33;
(6), get above-mentioned thick paste, add medically acceptable adjuvant, make various dosage forms.
7. the preparation method of medicine according to claim 6, is characterized in that: in step (2): decoct with water 2 times; Decoct for the first time institute's amount of water and be 8 times of raw material weight, soak 1 hour, decoct 1-2 hour; Decocting is for the second time to add water 6 times to measure, and soaks 1 hour, and decoction 1-2 hour, in step (3): be at 70-80 ℃, be concentrated to relative density and be 1.07 clear paste; In step (4): adding ethanol to make containing alcohol amount is 65%, leaves standstill and within 2436 hours, carries out precipitate with ethanol; In step (5): the precipitate of precipitate with ethanol gained is fully washed with the ethanol of 50-60%, and the filtrate of cleaning mixture and precipitate with ethanol gained merges; By the decompression filtrate recycling ethanol after merging, be condensed into thick paste.
8. the preparation method of medicine according to claim 7, step (6) is wherein: the thick paste of obtaining, add cane sugar powder, dextrin soft material processed, ovendry power adds appropriate wetting agent after pulverizing, and granulates dry.
9. the preparation method of medicine according to claim 8, wherein in step (1): the consumption of 20 Herba indigoferae Pseudotinctoriae is counted with weight portion: Flos Lonicerae 80, Cortex Phellodendri 50, Rhizoma Dioscoreae Septemlobae 40, Herba Spirodelae 30, Flos Chrysanthemi Indici 50, Radix Arnebiae (Radix Lithospermi) 40, Cortex Moutan 40, Radix Saposhnikoviae 50, Rhizoma Smilacis Glabrae 40, the Fructus Kochiae 50, Fructus Forsythiae 45, Radix Salviae Miltiorrhizae 110, Radix Glycyrrhizae 60, the Radix Rehmanniae 120, Placenta Hominis 110, Semen Persicae 40, Zaocys 30, favus skin 45, Caulis Spatholobi 50, Herba Schizonepetae 30, Herba Hedyotidis Diffusae 70;
In step (6): 1 part of the thick paste of obtaining, add 1.8 parts of cane sugar powders, 2.1 parts of soft materials processed of dextrin, add ethanol after ovendry power, cross 14 mesh sieves and granulate, 55-65 ℃ of oven dry; Granulate, sieves, subpackage.
10. the application of the medicine described in above-mentioned arbitrary claim in the dermopathic medicine of preparation treatment.
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| CN111228429A (en) * | 2020-02-24 | 2020-06-05 | 薛飞 | A compound composition containing Chinese medicinal materials and western medicines for treating dermatoses, and its preparation method |
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