CN106074740A - A kind of liniment treating pressure sore and preparation method thereof and using method - Google Patents
A kind of liniment treating pressure sore and preparation method thereof and using method Download PDFInfo
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- CN106074740A CN106074740A CN201610409309.5A CN201610409309A CN106074740A CN 106074740 A CN106074740 A CN 106074740A CN 201610409309 A CN201610409309 A CN 201610409309A CN 106074740 A CN106074740 A CN 106074740A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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Abstract
A kind of liniment treating pressure sore and preparation method thereof and using method, the invention belongs to technical field of traditional Chinese medicines, for the problem solving pressure sore, the present invention provides the preparation method of a kind of liniment treating pressure sore, described method comprises the following steps that A. takes fresh peony leaves, cleaning, normal temperature ventilation is placed 68 hours, dries；B. the honey with weight such as described peony leaves is taken；C. the peony leaves dried and standby honey are used gamma-rays illumination-based disinfection 5～10min；D. with the scissors after sterilizing, peony leaves is shredded, be then milled to paste；E. in described paste, add honey, continue to mill and stir to being evenly distributed, obtain described liniment.The beneficial effects of the present invention is, a kind of par is provided, easily obtains, and the liniment that the treatment works well.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicines, specifically, be a kind of liniment treating pressure sore.
Background technology
Pressure sore (pressure ulcer, PU) is also referred to as pressure ulcer or bedsore, is common in clinical position
One of complication, the current research discovery of pressure sore advisory group of the U.S.: the damaging part of pressure sore is to be confined to skin or subcutaneous group
Knitting, bone protruding part is its predilection site, and it occurs with pressure, frictional force or/and shearing force relation is the closest.
Pressure sore is one of common difficulty of being faced of world today's healthcare facility, is also to have prominent negative effect
One of health problem.The epidemiological study of this disease shows: have the incidence of 3%-12% the patient being in hospital, wherein with old age
The incidence of patient is the highest, is 10%-25%, and pressure sore may result in the death rate and increases by 6 times, then sends out in Patients of Spinal
Raw rate is higher, reaches 25%-85%, and 8% is relevant with death.Therefore, Chinese scholars is all devoted to pressure sore pathogenesis, preventing and treating
The clinical research of method and experimental study.
At the bone knuckle for often easy pressurized for the predilection site of pressure sore, such as sacrococcygeal region, heel, crista iliaca, omoplate apophysis
Place etc..It is difficult to Clinical symptoms healedmyocardial, that complexity chronic wounds is pressure sore.The tissue damage of III phase pressure sore is relatively deep, muscle,
Blood vessel, nerve etc. all have damage in various degree, repair difficulty bigger；And there may be and move under water or sinus, clean, drainage relatively
Difficulty, easily causes wound exudate and gathers in a large number, due in sepage rich in some insoluble media, including suppression wound healing
Inflammatory factor, therefore hinder wound healing；It further, since slough is easily by proteolysis, is bacterial growth and breeding
Good environment is provided, causes this phase pressure sore to have infection in various degree or bacteria planting, a large amount of endotoxin quilt of bacterium release
Wound bed absorbs, and causes cytotoxic, has a strong impact on wound healing.This phase pressure sore is generally more refractory more, if this phase pressure sore is long-term
Do not heal, or cannot get sufficient treatment and can produce various complication further, including the multidrug resistant whole body of wound local bacterial
Infect (bacteremia, septicemia), osteomyelitis etc..In addition, the long-term disunion of wound also has the possibility of canceration, i.e. squamous cell carcinoma
(Marjolin's ulcer).But, the concurrent pressure sore majority of long-term bedridden patients be III phase and more than, bring greatly to patient
Misery, has a strong impact on the quality of life of patient and family members thereof, is emphasis and the difficult point of domestic and international nurse's nursery work.
The western medicines in treatment method of pressure sore is various, external treatment of tcm include Resina Draconis, elephant hide myogenic cream, Shengji Yuhong Gao,
Superior sore throat powder, burst more spirit, MEBO, aloe, Shengji San, Ma Yinglong Emplastrum Moschus, egg membrane, sores plaster, safflower tincture,
Apply outside the medicines such as bedsore spirit；Western medical treatment method has painting outside gentamicin, metronidazole, vaseline respectively, or infrared lamp irradiates, routine
Change dressings.Having scholar to analyze discovery through Meta, external treatment of tcm treatment bedsore does not only have good curative effect, and controls with doctor trained in Western medicine
Treatment is compared, and has obvious curative effect advantage.
Content of the invention
It is an object of the invention to, based on pressure sore pathogenesis, use pure natural medical and food to join as medicine
Side, merges a kind of medicine with good treatment pressure sore prepared by herbal pharmacology effect.
For achieving the above object, the present invention provides a kind of following technical scheme:
The preparation method of a kind of liniment treating pressure sore, described method comprises the following steps that
A. taking fresh peony leaves, by fresh peony leaves with after distilled water wash clean, 6-8 hour is placed in normal temperature ventilation, dries in the air
Dry；
B. the honey with weight such as described peony leaves is taken；Described honey refers to ripe unprocessed Fresh Honey, described
Ripe unprocessed Fresh Honey refer to fresh, shake out after not through the honey of any processing；And there is moderate activity,
PH value 3. 30～4. 56, this pH value can help to suppress the growth and breeding of multiple pathogens；Moisture weight content is less than 20%, also
Raw sugar weight content be more than 76%, high reduced sugar, can suppress many pathogen；Enzyme values is more than 8, especially contains in honey
Glucose oxidase, it has the catalase of antibacterial action with glucose effect, bacteriostasis clearly, but due to
Enzyme is very sensitive to heat, in process, it is easy to can lose antibacterial action, so in the application, maturation is unprocessed newly
Fresh honey is necessary condition；
C. the peony leaves dried and standby honey are used gamma-rays illumination-based disinfection 5～10min；
D. carry out according to the method for surgery hand-wrist bones.Take appropriate hand disinfectant smear to each position of both hands, forearm and on
Under arm 1/3, and conscientiously rubbing 2-6min, washing down under both hands, forearm and upper arm 1/3 with circulating water, aseptic towel is thoroughly dried.Flowing
Water should reach the regulation of " standards for drinking water quality " (GB5749-2006).
The peony leaves dried is shredded by the scissors through pressuresteam sterilization E. providing with disinfection and supply center, is cut into face
Amass the fractionlet for about 1cm2, the peony leaves that the mortar through pressuresteam sterilization providing with disinfection and supply center will shred
Little slice lapping, milling time is 5-10 minute, is milled to paste；
E. in described paste, add honey, continue to grind, stir to paste, obtain described liniment.
F: ground liniment is positioned over sterile vessel, with standby.
Further, in step D, shred peony leaves for 0.8-1.2cm2Fractionlet.
The using method of a kind of liniment treating pressure sore, comprises the steps: that taking described liniment is positioned over
On aseptic oil gauze, be affixed on the pressure sore surface of a wound, coverage rate on the pressure sore surface of a wound for the liniment surface of a wound to be exceeded outer rim 5mm with
On, thickness on the pressure sore surface of a wound for the liniment is 3mm, and outer layer medical proof fabric fixed drug, in case medicine comes off, every day changes
Medicine once, treats 2-4 week altogether.
A kind of liniment treating pressure sore, described liniment includes honey and peony leaves paste, both
Ratio is 1:1.
Ancient books Shennong's Herbal is recorded: " tree peony, taste is pungent, cold.Main fever and chills, apoplexy, convulsion, frightened epilepsy, perverse trend, remove
Heavily fortified point, hemostasis stays house stomach, five viscera settling, treats ulcerative carbuncle." peony leaves has sudden change anti-oxidant, antibacterial, anti-, antitumor etc., in addition, male
Pellet leaf is cheap, draws materials conveniently, uses simultaneously and has bowl spares, moisturizes, pain relieving, and removing toxic substances is controlled sore outside can be used for and do not held back, scald
Honey as matrix, reduce scattering and disappearing of the red leaf moisture content of thing, make the III phase pressure sore surface of a wound be in wet environment.
Peony leaves: taste is pungent, cold.Main fever and chills, apoplexy, convulsion, frightened epilepsy, perverse trend, except heavily fortified point, hemostasis stays house stomach, pacifies five
Dirty, treat ulcerative carbuncle；There is sudden change anti-oxidant, antibacterial, anti-, antineoplastic effect.
Honey: sweet is flat.Return lung, spleen, large intestine channel.Main bowl spares, moisturizes, pain relieving, removing toxic substances.For the empty pain of gastral cavity abdomen, the dryness of the lung is done
Cough, the dry constipation of intestines；Control outward sore not hold back, scald.
The mechanism of action of honey: 1. honey in faintly acid, and the optimum pH value of bacterial growth is 7.2-7.4, existing
Proving for pharmacology, not heated natural honey is to suppurative staphylococcus aureus, beta hemolytic streptococcus, green pus bar
Bacterium, part Escherichia coli all have obvious bactericidal action.The high osmosis that multiple saturated sugar in honey is formed, destroys the life of bacterium
Long environment, makes bacterium dehydration death；2. honey makes the surface of a wound moisten, and moistening surface of a wound environment meets modern wound wet union side
Method, promotes the effect of wound active material, absorbs the toxicity secretion of wound, is difficult to adhesion, mitigates mechanical injuries, changes simultaneously
The blood circulation of kind pressure sore, suppression local tissue necrosis and bacterial growth, reduce the surface of a wound and ooze out, promote body tissue regeneration, add
Speed ulcer healing；3. honey is at normal temperatures in highly viscous state, can prevent and stop invasion or the diffusion of bacterium, changes wound
The microenvironment of local.The hypertonicity of honey, can draw liquid and the moist environment that keeps wound healing from the circulation of deep layer,
Mitigate pain of patients changing dressing, to surface of a wound nonirritant, not damaged, have no side effect, the immunologic function of human body can also be regulated；4. honey
In glucose oxidase and gluconic acid diluted by wound fluid, produce low concentration hydrogen peroxide, peroxidating Hydrogen Energy sting
Swash the Angiogenesis of transport oxygen and nutrition, promote new connective tissue growth, strengthen the repair of body；5. honey is containing abundant
The nutriments such as sugar, vitamin, amino acid, trace element and enzyme, directly feed histocyte and utilize, provide energy, promote wound
Mouth regeneration, improves the resistance against diseases of body.
The beneficial effects of the present invention is, a kind of par is provided, easily obtains, and the medicine for external application that the treatment works well
Thing.
Detailed description of the invention
Below in conjunction with specific embodiment, this case is described further:
Embodiment 1
A. taking fresh peony leaves, by fresh peony leaves with after distilled water wash clean, 6-8 hour is placed in normal temperature ventilation, dries in the air
Dry；
B. the honey with weight such as described peony leaves is taken;
C. the peony leaves dried and standby honey are used gamma-rays illumination-based disinfection 8min；
D. carry out according to the method for surgery hand-wrist bones.Take appropriate hand disinfectant smear to each position of both hands, forearm and on
Under arm 1/3, and conscientiously rubbing 2-6min, washing down under both hands, forearm and upper arm 1/3 with circulating water, aseptic towel is thoroughly dried, flowing
Water should reach the regulation of " standards for drinking water quality " (GB5749-2006).
The peony leaves dried is shredded by the scissors through pressuresteam sterilization E. providing with disinfection and supply center, is cut into face
Amass as 1cm2The fractionlet of left and right, the peony leaves that the mortar through pressuresteam sterilization providing with disinfection and supply center will shred
Little slice lapping, milling time is 5-10 minute, is milled to paste, and described paste humidity is 20%；
E. in described paste, add honey, continue to grind, stir to paste, obtain described liniment, paste
With the weight of honey than for 1:1.
F: ground liniment is positioned over sterile vessel, with standby.
G: be placed in liniment on aseptic oil gauze, (area is for beyond surface of a wound outer rim 5mm, thickness to be affixed on the pressure sore surface of a wound
For 3mm), outer layer medical proof fabric fixed drug, in case medicine comes off, change dressings every day once, general 3 days, it is seen that wound exudate
Reducing, substantially not having smell, skin takes a turn for the better, and treats 5 days, and the surface of a wound can grow fresh granulation tissue, general treatment 2 weeks-4
In week, pressure sore can be healed.
Case one:
Lin, female, 62 years old, unfavorable more than 2 years of limb activity on the right side of patient, CBR, right side sacrococcygeal region showed 3*
4.5cm2The III phase pressure sore of size, color is red, a small amount of sepage, has a little smell, and surrounding skin is peeled, and gives peony leaves 100g,
It is prepared according to the preparation method of plaster, standby paste peony leaves is taken and is placed in right amount on aseptic oil gauze, will contain aseptic
Yarn side is affixed on the pressure sore surface of a wound (area for beyond surface of a wound outer rim 5mm, thickness is 3mm), outer layer medical proof fabric fixed drug,
In case medicine comes off.Changing dressings every day once, treating the 3rd day, sepage absorbs, and smell disappears, and treats the 5th day, grows fresh granulation
Tissue, treats the 10th day, and the surface of a wound covers with fresh granulation tissue, smooth, treats 14 days altogether, and pressure sore is healed.
Case two:
Lee, man, 74 years old, right hip fracture was postoperative, and after lying up two weeks, right heel skin shows a 3*1.5cm2Greatly
Little III phase pressure sore, color is pink, has a small amount of sepage, has a little smell, and surrounding skin is red and swollen, gives peony leaves 100g and honey
100g, is prepared according to the preparation method of plaster, standby paste peony leaves and honey mixt are taken be placed in right amount aseptic
On oil gauze, will contain and aseptic be affixed on the pressure sore surface of a wound (area for beyond surface of a wound outer rim 5mm, thickness is 3mm) by yarn side, outer layer is used
Medical proof fabric fixed drug, in case medicine comes off.Change dressings every day once, treat the 3rd day, without sepage, odorlessness, grow green meat
Bud tissue, treats the 7th day, and the surface of a wound covers with fresh granulation tissue, smooth, treats 12 days altogether, and pressure sore is healed.
The medicine for the treatment of pressure sore described in the present patent application, low cost, evident in efficacy, have no side effect, there is wide answering
Use prospect.
Claims (3)
1. the preparation method of the liniment treating pressure sore, it is characterised in that described method comprises the following steps that
A. taking fresh peony leaves, cleaning, 6-8 hour is placed in normal temperature ventilation, dries；
B. taking the honey with weight such as described peony leaves, described honey refers to ripe unprocessed Fresh Honey, its pH value
Being 3. 30～4. 56, moisture weight content is below 20%, and reduced sugar weight content is more than 76%, and enzyme values is more than 8；
C. the peony leaves dried and standby honey are used gamma-rays illumination-based disinfection 5～10min；
D. with the scissors after sterilizing, peony leaves is shredded, be then milled to paste；
E. in described paste, add honey, continue to mill and stir to being evenly distributed, obtain described liniment.
2. preparation method as claimed in claim 1, it is characterised in that in step D, shred peony leaves for 0.8-1.2cm2's
Fractionlet.
3. the liniment treating pressure sore, it is characterised in that described liniment includes honey and peony leaves paste
Thing, both weight is than for 1:1.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610409309.5A CN106074740A (en) | 2016-06-13 | 2016-06-13 | A kind of liniment treating pressure sore and preparation method thereof and using method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610409309.5A CN106074740A (en) | 2016-06-13 | 2016-06-13 | A kind of liniment treating pressure sore and preparation method thereof and using method |
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| Publication Number | Publication Date |
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| CN106074740A true CN106074740A (en) | 2016-11-09 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610409309.5A Pending CN106074740A (en) | 2016-06-13 | 2016-06-13 | A kind of liniment treating pressure sore and preparation method thereof and using method |
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| CN (1) | CN106074740A (en) |
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- 2016-06-13 CN CN201610409309.5A patent/CN106074740A/en active Pending
Non-Patent Citations (5)
| Title |
|---|
| 崔飞飞，等: "天然蜂蜜联合紫花地丁敷料促进Ⅲ期压疮愈合的临床观察", 《护理研究》 * |
| 范青生，等: "《保健食品配方原理与依据》", 28 February 2007, 中国医药科技出版社 * |
| 葛英: "不同浓度蜂蜜抑菌性实验报告", 《蜜蜂杂质》 * |
| 陈赟: "牡丹叶湿敷对Ⅲ期压疮抗氧化机制研究", 《中国优秀硕士学位论文全文数据库（医药卫生科技辑）》 * |
| 雷运清，等: "《中华蜜蜂活框饲养技术》", 31 July 2013, 湖北科学技术出版社 * |
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Application publication date: 20161109 |
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