CN106074237A - A kind of plant extract type whitening water - Google Patents
A kind of plant extract type whitening water Download PDFInfo
- Publication number
- CN106074237A CN106074237A CN201610413429.2A CN201610413429A CN106074237A CN 106074237 A CN106074237 A CN 106074237A CN 201610413429 A CN201610413429 A CN 201610413429A CN 106074237 A CN106074237 A CN 106074237A
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- China
- Prior art keywords
- extract
- spartina alterniflora
- water
- dorema ammoniacum
- ammoniacum resin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/731—Cellulose; Quaternized cellulose derivatives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
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- Birds (AREA)
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- Oil, Petroleum & Natural Gas (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
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Abstract
The invention discloses a kind of plant extract type whitening water, including: Spartina alterniflora's extract, glycerol, triethanolamine, sodium lactate (60%), deionized water, hydroxymethyl cellulose and Dorema ammoniacum resin extract.The present invention using Spartina alterniflora as the primary raw material of astringent, there is the nutrient such as fatty acid, Spartina alterniflora's total flavones, there is the effect of anti-defying age oxidation, and bactericidal effect is preferable, find through experimental study, add Dorema ammoniacum resin extract, with Spartina alterniflora's fusion each other, there is whitening effect, using Spartina alterniflora as the primary raw material of astringent, with low cost.
Description
Technical field
The present invention relates to a kind of plant extract type whitening water.
Background technology
Astringent is referred to as by cosmetic water, toner/smoothing toner, astringent lotion, is the cosmetics of a kind of transparent liquid, spreads upon the table of skin
Face, is used for cleaning skin, the health of holding skin.Cosmetic water, astringent lotion and toner/smoothing toner difference are not too big, cosmetic water, convergence
It is hotter that water is more suitable for weather, compares on the face and likes that fuel-displaced weather uses, and the season that toner/smoothing toner is more suitable for being dried uses.Astringent exists
Basis skin protection has acted the effect taken over from the past and set a new course for the future.
Spartina alterniflora is subordinate to grass family, rice grass belongs to, and is a kind of herbaceos perennial, and it originates from America the Atlantic coast
And the Gulf of Mexico, suitably move in Intertidal zone.Due to Spartina alterniflora's straw intensive sturdy, underground rhizome is flourishing, it is possible to promote mud
Husky rapid subsidence and alluvial, therefore, 20 beginning of the century many countries, in order to protect beach bank protection, created land with silt, are successively introduced.Though
So Spartina alterniflora has important ecological functions in Coastal Ecosystem, but its breeding superpower in tidal beach wetland habitat
Power, threatens the marine marsh endemic species in the whole world, so many countries implement on a large scale as instruction plant
Control plan.The relevant report preparing astringent for raw material currently with Spartina alterniflora does not also have.
Dorema ammoniacum resin, for the resin of samphire Ammonia grindelia DoremaammoniacumD.Don..Spring Mo
Early summer full-bloom stage, to the just fruit phase, hurts cervical region, collects the lactescence natural gum oozed out, dries in the shade.Recorded in 1998 that " the China people are altogether
With state's the Sanitation Ministry medicine standard Uigurs medicine fascicle ".There is cold expelling gas, dry cold-damp, softening the hard mass relieving constipation, take out and let out body deep layer anomalous body
Liquid, opens effect of liver spleen impatency.For cold arthralgia, ankylosis, skin is the most swollen, oxter and Neck lymphatic tuberculosis,
Chronic cough abundant expectoration, lusterless complexion.
Summary of the invention
The problem existed for above-mentioned prior art, the present invention provides a kind of plant extract type whitening water, utilizes flower rice mutually
Grass is for prepare for main raw material(s), cheap, and whitening effect is good.
To achieve these goals, the technical solution used in the present invention is: a kind of plant extract type whitening water, including: mutually
Flower rice grass extract, glycerol, triethanolamine, sodium lactate (60%), deionized water, hydroxymethyl cellulose, Dorema ammoniacum resin are extracted
Thing.
Described whitening water formula is calculated by weight:
Spartina alterniflora's extract 20-30 part,
Glycerol 7-10 part,
Triethanolamine 6-10 part,
Sodium lactate (60%) 5-7 part,
Deionized water 70-75 part,
Hydroxymethyl cellulose 3-6 part,
Dorema ammoniacum resin extract 4-6 part.
Described Spartina alterniflora's extract is by Spartina alterniflora's raw material pulverizing, adds 7-9 times amount 80-95% alcohol reflux
Twice, merging twice extracting solution and reclaim ethanol, concentrated solution adds in macroporous resin and adsorbs, with 5-10 times of column volume 50-90% ethanol
Eluant solution, collects eluent concentrating under reduced pressure, obtains concentrated solution；Above-mentioned concentrated solution adds ethyl acetate extraction, and extract continues dense
Shorten extractum into.
The preparation method of Dorema ammoniacum resin extract is:
Dorema ammoniacum resin, pulverizes, excessively 10-50 mesh sieve, employing supercritical carbon dioxide extraction method, extraction temperature 40 DEG C-50 DEG C,
Extracting pressure 20MPa-30MPa, extraction time 1-2h, extract volatile oil, collects volatile oil, obtains Dorema ammoniacum resin extract.
Spartina alterniflora as the primary raw material of astringent, is had the nutrition such as fatty acid, Spartina alterniflora's total flavones by the present invention
Element, has the effect of anti-defying age oxidation, and bactericidal effect is preferable, find through experimental study, add Dorema ammoniacum resin
Extract and Spartina alterniflora's fusion each other have collaborative whitening effect, the most former using Spartina alterniflora as astringent
Material, with low cost.
Detailed description of the invention
Example of the present invention is the description of the invention and can not limit the present invention, in the implication suitable with the present invention
With any change in scope and adjustment, all it is considered as within the scope of the invention.
Embodiment 1:
Spartina alterniflora's raw material pulverizing, adds 7-9 times amount 80-95% alcohol reflux twice, merges twice extracting solution and reclaims second
Alcohol, concentrated solution adds in macroporous resin and adsorbs, and with 5-10 times of column volume 50-90% ethanol solution eluting, collects eluent decompression dense
Contracting, obtains concentrated solution；Above-mentioned concentrated solution adds ethyl acetate extraction, and extract continues to be condensed into Spartina alterniflora's extract.
Dorema ammoniacum resin, pulverizes, excessively 10-50 mesh sieve, employing supercritical carbon dioxide extraction method, and extraction temperature 40 DEG C-
50 DEG C, extracting pressure 20MPa-30MPa, extraction time 1-2h, extract volatile oil, collect volatile oil, obtain Dorema ammoniacum resin and carry
Take thing.
Described whitening water formula is calculated by weight:
Spartina alterniflora's extract 20 parts, glycerol 7 parts, triethanolamine 6 parts, sodium lactate (60%) 5 part, deionized water 75 parts, hydroxyl
Methylcellulose 3 parts, Dorema ammoniacum resin extract 4 parts.
Embodiment 2:
Method be that embodiment 1 is identical, difference is that formula is: Spartina alterniflora's extract 30 parts, glycerol 10 parts, triethanolamine
10 parts, sodium lactate (60%) 7 part, deionized water 75 parts, hydroxymethyl cellulose 6 parts, Dorema ammoniacum resin extract 6 parts.
Embodiment 3:
Method be that embodiment 1 is identical, difference is that formula is: Spartina alterniflora's extract 25 parts, glycerol 8 parts, triethanolamine 8
Part, sodium lactate (60%) 6 part, deionized water 70 parts, hydroxymethyl cellulose 5 parts, Dorema ammoniacum resin extract 5 parts..
Comparative example 1
Method be that embodiment 1 is identical, difference is that formula is: Spartina alterniflora's extract 30 parts, glycerol 10 parts, triethanolamine
10 parts, sodium lactate (60%) 7 part, deionized water 75 parts.
Comparative example 2
Method be that embodiment 1 is identical, difference is that formula is: glycerol 10 parts, triethanolamine 10 parts, sodium lactate (60%) 7
Part, deionized water 75 parts, hydroxymethyl cellulose 10 parts.
Test method
Effect example:
Detection method:
Melanin genesis test in suppression mouse melanin cell.
By B16 mouse melanin tumor cell with 1 × 105The density of individual/ml is connected to the culture dish of a diameter of 9cm, at 37 DEG C
5%CO2Under conditions of cultivate 2 days, abandon supernatant, add the sample solution 18-22ml after filtration sterilization, be then incubated for 3 days, abandon
Supernatant, PBS washs, and every hole adds the trypsin solution peptic cell 3min of 0.5ml mass percent 0.2%, and every ware adds 2ml dimension
Hold liquid and terminate digestion. after piping and druming mixing, every kind of concentration is taken out 0.5ml and is made cell counting. remaining cell suspension with 2500r/min from
Heart 5min, abandons supernatant, adds NaoH solution in precipitation, and heating makes melanin dissolve, and selects the enzyme linked immunological of 490nm wavelength
Absorbance is surveyed on detector.
B16 cell suppression ratio=(1-(medicine hole absorbance+medicine porocyte density)+(control wells absorbance+right
According to porocyte density)) × 100%.
Melanin genesis test in suppression mouse melanin cell, result is as follows
Suppression ratio (%)
Embodiment 1 66.2
Embodiment 2 63.7
Embodiment 3 62.3
Comparative example 1 20.3
Comparative example 2 10.5
Above-mentioned test result indicate that, Dorema ammoniacum resin extract and Spartina alterniflora's fusion each other have the merit of collaborative whitening
Effect, can effectively suppress melanin to generate, and effect is notable.
Above-described embodiment is the present invention preferably embodiment, but embodiments of the present invention are not by above-described embodiment
Limiting, the change made under other any spirit without departing from the present invention and principle is modified alternative combinations and is simplified,
All should be the substitute mode of equivalence, within being included in protection scope of the present invention.
Claims (4)
1. a plant extract type whitening water, it is characterised in that including: Spartina alterniflora's extract, glycerol, triethanolamine, lactic acid
Sodium (60%), deionized water, hydroxymethyl cellulose and Dorema ammoniacum resin extract.
A kind of plant extract type whitening water the most according to claim 1, it is characterised in that described whitening water formula is by weight
Amount is calculated as:
Spartina alterniflora's extract 20-30 part,
Glycerol about 7-10 part,
Triethanolamine 6-10 part,
Sodium lactate (60%) 5-7 part,
Deionized water about 70-75 part,
Hydroxymethyl cellulose 3-6 part,
Dorema ammoniacum resin extract 4-6 part.
A kind of plant extract type whitening water the most according to claim 1, it is characterised in that Spartina alterniflora's extract makes work
Skill comprises the following steps: Spartina alterniflora's extract is by Spartina alterniflora's raw material pulverizing, adds about 7-9 times amount 80-95% alcohol reflux
Extracting twice, merge twice extracting solution and reclaim ethanol, concentrated solution adds in macroporous resin and adsorbs, with 5-10 times of column volume 50-90%
Ethanol solution eluting, collects eluent concentrating under reduced pressure, obtains concentrated solution；Above-mentioned concentrated solution adds ethyl acetate extraction, and extract continues
Continue and be condensed into extractum.
A kind of plant extract type whitening water the most according to claim 2, it is characterised in that including: Dorema ammoniacum resin extract
Preparation method be:
(1) Dorema ammoniacum resin, pulverizes, and crosses 10-50 mesh sieve, uses supercritical carbon dioxide extraction method, extraction temperature 40 DEG C-50
DEG C, extracting pressure 20MPa-30MPa, extraction time 1-2h, extract volatile oil, collect volatile oil, obtain Dorema ammoniacum resin extract
Thing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610413429.2A CN106074237A (en) | 2016-06-14 | 2016-06-14 | A kind of plant extract type whitening water |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610413429.2A CN106074237A (en) | 2016-06-14 | 2016-06-14 | A kind of plant extract type whitening water |
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| Publication Number | Publication Date |
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| CN106074237A true CN106074237A (en) | 2016-11-09 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201610413429.2A Pending CN106074237A (en) | 2016-06-14 | 2016-06-14 | A kind of plant extract type whitening water |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105997641A (en) * | 2016-06-14 | 2016-10-12 | 孙跃 | Plant extracting type toning lotion |
| CN107802593A (en) * | 2017-12-07 | 2018-03-16 | 广州赛莱拉干细胞科技股份有限公司 | A kind of lightening compositions containing Radix Astragali stem cell extract and its application |
| KR20190135245A (en) * | 2018-05-28 | 2019-12-06 | 영남대학교 산학협력단 | Composition for anti-oxidation, skin whitening comprising Spartina alterniflora extracts as an active ingredient |
-
2016
- 2016-06-14 CN CN201610413429.2A patent/CN106074237A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105997641A (en) * | 2016-06-14 | 2016-10-12 | 孙跃 | Plant extracting type toning lotion |
| CN107802593A (en) * | 2017-12-07 | 2018-03-16 | 广州赛莱拉干细胞科技股份有限公司 | A kind of lightening compositions containing Radix Astragali stem cell extract and its application |
| KR20190135245A (en) * | 2018-05-28 | 2019-12-06 | 영남대학교 산학협력단 | Composition for anti-oxidation, skin whitening comprising Spartina alterniflora extracts as an active ingredient |
| KR102077069B1 (en) * | 2018-05-28 | 2020-02-13 | 영남대학교 산학협력단 | Composition for anti-oxidation, skin whitening comprising Spartina alterniflora extracts as an active ingredient |
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Application publication date: 20161109 |