CN105725209A - Dendrobium officinale granules and preparation method thereof - Google Patents

Dendrobium officinale granules and preparation method thereof Download PDF

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Publication number
CN105725209A
CN105725209A CN201610058426.1A CN201610058426A CN105725209A CN 105725209 A CN105725209 A CN 105725209A CN 201610058426 A CN201610058426 A CN 201610058426A CN 105725209 A CN105725209 A CN 105725209A
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parts
herba dendrobii
dendrobium officinale
water
concentrated extract
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CN201610058426.1A
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Chinese (zh)
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蒋承建
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Guangxi University
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Guangxi University
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses Dendrobium officinale granules. The Dendrobium officinale granules are prepared from the following components in parts by weight: 18-30 parts of Dendrobium officinale, 35-48 parts of Poria cocos, 9-20 parts of radix ginseng, 5-17 parts of wolfberry fruit, 18-32 parts of Chinese yam, and 19-33 parts of coix seed. The Dendrobium officinale granules can be used for regulating the immune function, resisting fatigue and tonifying qi and yin, is suitable for people with weak constitution and fatigability to take, especially has an excellent effect for rehabilitation after illness and on patients with excess fatigue and deficiency of lung and stomach yin, and can be used for eliminating fatigue and weakness of people caused by busy work and study so as to effectively improve the work and study efficiency.

Description

A kind of dendrobium officinale granula and preparation method thereof
Technical field
The present invention relates to food processing field, particularly relate to a kind of dendrobium officinale granula and preparation method thereof.
Background technology
Herba Dendrobii belongs to the orchid family herbaceos perennial, is a kind of famous and precious resources of medicinal plant, containing polysaccharide, stilbene The Multiple components such as class, alkaloid, aminoacid and trace element, have enhancing immunity, stimulate hemopoietic, antioxidation, antitumor, anti-tired Labor, blood sugar lowering, the multiple biological activity such as promote the production of body fluid.Dendrobium officinale is typically born in height above sea level at the mountain region of about 1600 meters and gas Under the conditions of waiting warm and moist and half cloudy half light.Dendrobium officinale is distributed in the countries such as East Asia, Southeast Asia and Australia and ground District;The ground such as Anhui, Zhejiang, Yunnan, Guangxi, Hunan, Guizhou it are distributed mainly in China.Herba Dendrobii is to have been carried out in China Artificial culture, yield rise year by year.After iron-sheet dendrobe fresh product compares deep processing, product has been maximally maintained Herba Dendrobii Effective ingredient, and in Herba Dendrobii rich in effective ingredient be also easier to be absorbed by human body.Due to iron sheet stone Dry measure used in former times natural propagation rate is extremely low, adds that people are the most immoderate to excavate, and in recent years, wild resource is on the verge of exhaustion, only passes through Tissue-culturing rapid propagation nursery, implements artificial culture and produces, could ensure the sustainable development of Herba Dendrobii Chinese crude drug, meet market need Ask.Up to the present, being fully dissolved out for Herba Dendrobii effective ingredient and absorb again without good solution, this is right A kind of huge loss beyond doubt for this rare medicinal herbs.
Chinese medicine granules refers to extract and proper auxiliary materials or the mixing of part fine medicinal material powder, the dry granule made of Chinese crude drug Shape dosage form.Chinese medicine granules is to combine the feature of decoction, medicated wine and syrup and a kind of form of Chinese drug of growing up, both keeps Decoction absorbs rapid feature fast, effective, overcomes again before decoction is taken and to decoct temporarily, be long placed in and the most mould lose rotten feature, Also can cover the bitterness of some Chinese medicine.Alternatively " Chinese medicine granules is prepared slices of Chinese crude drugs Processing methods technique and form improvement grinds The progress studied carefully, is based on Chinese medical theory clinical practice needs, and Chinese crude drug and tcm and herbal slice is carried out the one of special processing Plant the novel form increased evident in efficacy being easy to carry and taking ".Start to come across the seventies in last century, take owing to it carries Convenient, the Chinese medicine in the eighties in last century produces in industry once with the speed development being incremented by 41.9% year.
The extraction of Chinese medicinal granule, concentrate, be dried, adjuvant selects, method of granulating and granularity selection etc. all should be carried out preferably With detailed research.Owing to Chinese medicine ingredients is complicated, should embody the self-character of guidance of traditional Chinese medicine theory, Chinese medicine to be retained passes Controlling agent reasonably essence, attention composition and the Close relation etc. of curative effect, so the problem that the preparation of Chinese medicine granules is crucial It is the technique of extracting to crude drug and dry technology research.
Extraction is the unit operation of separating effective ingredient from medicinal raw material, is directly connected to containing of product effective ingredient Amount, affects the enforcement of inherent quality, clinical efficacy, economic benefit and GMP.Research and the production of Chinese medicine preparation are former from conventional formulation The ball of powder molding, the rise being scattered to extraction type preparation such as granule, extractum sheet, capsule, oral liquid, injection etc. and development, be The feature of half a century Chinese medicine preparation progress, belongs to and enters the period improving preparation from conventional formulation.Owing to Chinese medicine ingredients is multiple Miscellaneous, the self-character of guidance of traditional Chinese medicine theory to be embodied, the rational own job of Chinese medicine conventional formulation to be retained as far as possible, focus on composition The aspects such as the Close relation with curative effect, the research of extracting technique of Chinese medicine and selection are particularly significant, are also considerably complicated Problem.
Summary of the invention
In order to solve the deficiency that existing technology exists, the invention provides a kind of dendrobium officinale granula and preparation method thereof.
The technical scheme that the present invention provides is as follows:
A kind of dendrobium officinale granula, raw material forms according to following ratio of weight and number: Herba Dendrobii 18-30 part, Poria 35-48 Part, Radix Ginseng 9-20 part, Fructus Lycii 5-17 part, Rhizoma Dioscoreae 18-32 part, Semen Coicis 19-33 part.
Further illustrating, raw material forms according to following ratio of weight and number: Herba Dendrobii 20 parts, 38 parts of Poria, Radix Ginseng 10 parts, Fructus Lycii 15 parts, Rhizoma Dioscoreae 20 parts, Semen Coicis 25 parts.
Further illustrate, the preparation method of a kind of dendrobium officinale granula, comprise the steps:
(1) Herba Dendrobii is put in water clean up, dry rear cutout and become the Herba Dendrobii segment of a length of 0.2-0.6cm;
(2) being soaked in water by Herba Dendrobii segment, soak time is 5 hours;
(3) being put in water by Herba Dendrobii segment and decoct, decocting time is 2 hours, and temperature is 100-120 DEG C, obtains filtering residue A With filtrate A;
(4) filtering residue A Poria, Radix Ginseng, Fructus Lycii, Rhizoma Dioscoreae and Semen Coicis being put in water and decocted, decocting time is 1 hour, Temperature is 95-120 DEG C, obtains filtering residue B and liquor B;
(5) filtrate A and liquor B being stirred, pour in concentrating under reduced pressure tank after filtration, being evaporated to relative density is 1.15-1.20, obtains concentrated extract, and temperature is: 60-75 DEG C, and vacuum is: 0.07-0.09MPa,
(6) concentrated extract is placed under ultrasonic ultraviolet sterilization;
(7) adding quality in concentrated extract is concentrated extract cyclodextrin, is spray dried to extract powder;
(8) dry granulation, the granulate that sieves i.e. obtains Herba Dendrobii granule.
Herba Dendrobii is the dry stem of orchid Herba Dendrobii, sweet in the mouth, and cold nature returns stomach, kidney channel.There is stomach reinforcing raw Tianjin, the function of nourishing YIN and clearing away heat.Modern medicine and pharmacology research show, Herba Dendrobii mainly contain polysaccharide, aminoacid and trace element, The luxuriant and rich with fragrance chemical composition such as class and a small amount of alkaloid, has the pharmacological actions such as enhancing immunity, resisting fatigue, antitumor, blood sugar lowering.
Poria is the dry sclerotia of On Polyporaceae Poria, sweet in the mouth, light, and property is put down, GUIXIN, lung, spleen, kidney channel.There is profit Water eliminating dampness by diuresis, the function of spleen invigorating mind calming.Modern medicine and pharmacology research shows, Poria is mainly composed of β-pachyman and three mushrooms chemical combination Thing second phthalein pachymic acid, pachymic acid and 3 beta-hydroxy Pilus Caprae seu Ovis steroid trienic acids.There is the merits such as raising immunity, antitumor, anti-liver cirrhosis Energy.
Radix Ginseng is the dry root and rhizome of Araliaceae Radix Ginseng, sweet in the mouth, micro-hardship, and property is put down, and returns spleen, lung, heart channel.Have big Invigorating primordial QI, multiple arteries and veins takes off admittedly, and invigorating the spleen to benefit the lung promotes the production of body fluid, the function calmed the nerves.Modern medicine and pharmacology research shows, Radix Ginseng is mainly containing multiple people The compositions such as ginseng saponin, saccharide, volatile oil, peptide, aminoacid, trace element and organic acid, multivitamin, choline and enzyme.Have Resisting fatigue, enhancing immunity, antitumor, blood sugar lowering and the anti-ageing effect of waiting for a long time.
The method have the advantages that
A kind of dendrobium officinale granula that the present invention provides and preparation method thereof regulating immunological function, resisting fatigue, boosting qi and nourishing yin, Be applicable to have a delicate constitution and fatiguability person, especially to rehabilitation after being ill, overwork, lung-stomach yin deficiency shower has good work With, people are by the spiritlessness and weakness caused by busy working and learning in elimination, can be effectively improved working and learning efficiency.
Detailed description of the invention
Below in conjunction with the embodiment of the present invention, the technical scheme in the embodiment of the present invention is clearly and completely described, Obviously, described embodiment is only a part of embodiment of the present invention rather than whole embodiments.Based on the reality in the present invention Execute example, the every other embodiment that field those of ordinary skill is obtained under not making creative work premise, broadly fall into The scope of protection of the invention.
Embodiment 1
A kind of dendrobium officinale granula, raw material forms according to following ratio of weight and number: Herba Dendrobii 18 parts, 35 parts of Poria, Radix Ginseng 9 Part, Fructus Lycii 5 parts, Rhizoma Dioscoreae 18 parts, Semen Coicis 19 parts.
The preparation method of a kind of dendrobium officinale granula, comprises the steps:
(1) Herba Dendrobii is put in water clean up, dry rear cutout and become the Herba Dendrobii segment of a length of 0.2cm;
(2) being soaked in water by Herba Dendrobii segment, soak time is 5 hours;
(3) being put in water by Herba Dendrobii segment and decoct, decocting time is 2 hours, and temperature is 100 DEG C, obtains filtering residue A and filter Liquid A;
(4) filtering residue A Poria, Radix Ginseng, Fructus Lycii, Rhizoma Dioscoreae and Semen Coicis being put in water and decocted, decocting time is 1 hour, Temperature is 95 DEG C, obtains filtering residue B and liquor B;
(5) filtrate A and liquor B being stirred, pour in concentrating under reduced pressure tank after filtration, being evaporated to relative density is 1.15, obtain concentrated extract, temperature is: 60 DEG C, and vacuum is: 0.07MPa,
(6) concentrated extract is placed under ultrasonic ultraviolet sterilization;
(7) adding quality in concentrated extract is concentrated extract cyclodextrin, is spray dried to extract powder;
(8) dry granulation, the granulate that sieves i.e. obtains Herba Dendrobii granule.
Embodiment 2
A kind of dendrobium officinale granula, raw material forms according to following ratio of weight and number: Herba Dendrobii 30 parts, 48 parts of Poria, Radix Ginseng 20 parts, Fructus Lycii 17 parts, Rhizoma Dioscoreae 32 parts, Semen Coicis 33 parts.
The preparation method of a kind of dendrobium officinale granula, comprises the steps:
(1) Herba Dendrobii is put in water clean up, dry rear cutout and become the Herba Dendrobii segment of a length of 0.6cm;
(2) being soaked in water by Herba Dendrobii segment, soak time is 5 hours;
(3) being put in water by Herba Dendrobii segment and decoct, decocting time is 2 hours, and temperature is 120 DEG C, obtains filtering residue A and filter Liquid A;
(4) filtering residue A Poria, Radix Ginseng, Fructus Lycii, Rhizoma Dioscoreae and Semen Coicis being put in water and decocted, decocting time is 1 hour, Temperature is 120 DEG C, obtains filtering residue B and liquor B;
(5) filtrate A and liquor B being stirred, pour in concentrating under reduced pressure tank after filtration, being evaporated to relative density is 1.20, obtain concentrated extract, temperature is: 75 DEG C, and vacuum is: 0.09MPa,
(6) concentrated extract is placed under ultrasonic ultraviolet sterilization;
(7) adding quality in concentrated extract is concentrated extract cyclodextrin, is spray dried to extract powder;
(8) dry granulation, the granulate that sieves i.e. obtains Herba Dendrobii granule.
Embodiment 3
A kind of dendrobium officinale granula, raw material forms according to following ratio of weight and number: Herba Dendrobii 20 parts, 39 parts of Poria, Radix Ginseng 16 parts, Fructus Lycii 12 parts, Rhizoma Dioscoreae 20 parts, Semen Coicis 25 parts.
The preparation method of a kind of dendrobium officinale granula, it is characterised in that comprise the steps:
(1) Herba Dendrobii is put in water clean up, dry rear cutout and become the Herba Dendrobii segment of a length of 0.4cm;
(2) being soaked in water by Herba Dendrobii segment, soak time is 5 hours;
(3) being put in water by Herba Dendrobii segment and decoct, decocting time is 2 hours, and temperature is 110 DEG C, obtains filtering residue A and filter Liquid A;
(4) filtering residue A Poria, Radix Ginseng, Fructus Lycii, Rhizoma Dioscoreae and Semen Coicis being put in water and decocted, decocting time is 1 hour, Temperature is 95-120 DEG C, obtains filtering residue B and liquor B;
(5) filtrate A and liquor B being stirred, pour in concentrating under reduced pressure tank after filtration, being evaporated to relative density is 1.19, obtain concentrated extract, temperature is: 66 DEG C, and vacuum is: 0.08MPa,
(6) concentrated extract is placed under ultrasonic ultraviolet sterilization;
(7) adding quality in concentrated extract is concentrated extract cyclodextrin, is spray dried to extract powder;
(8) dry granulation, the granulate that sieves i.e. obtains Herba Dendrobii granule.
Above-described embodiment is the present invention preferably embodiment, but embodiments of the present invention are not by above-described embodiment Limit, the change made under other any spirit without departing from the present invention and principle, modify, substitute, combine, simplify, All should be the substitute mode of equivalence, within being included in protection scope of the present invention.

Claims (3)

1. a dendrobium officinale granula, it is characterised in that raw material forms according to following ratio of weight and number: Herba Dendrobii 18-30 Part, Poria 35-48 part, Radix Ginseng 9-20 part, Fructus Lycii 5-17 part, Rhizoma Dioscoreae 18-32 part, Semen Coicis 19-33 part.
A kind of dendrobium officinale granula the most according to claim 1, it is characterised in that raw material is according to following ratio of weight and number Composition: Herba Dendrobii 20 parts, 38 parts of Poria, Radix Ginseng 10 parts, Fructus Lycii 15 parts, Rhizoma Dioscoreae 20 parts, Semen Coicis 25 parts.
The preparation method of a kind of dendrobium officinale granula the most according to claim 1, it is characterised in that comprise the steps:
(1) Herba Dendrobii is put in water clean up, dry rear cutout and become the Herba Dendrobii segment of a length of 0.2-0.6cm;
(2) being soaked in water by Herba Dendrobii segment, soak time is 5 hours;
(3) being put in water by Herba Dendrobii segment and decoct, decocting time is 2 hours, and temperature is 100-120 DEG C, obtains filtering residue A With filtrate A;
(4) filtering residue A Poria, Radix Ginseng, Fructus Lycii, Rhizoma Dioscoreae and Semen Coicis being put in water and decocted, decocting time is 1 hour, Temperature is 95-120 DEG C, obtains filtering residue B and liquor B;
(5) filtrate A and liquor B being stirred, pour in concentrating under reduced pressure tank after filtration, being evaporated to relative density is 1.15-1.20, obtains concentrated extract, and temperature is: 60-75 DEG C, and vacuum is: 0.07-0.09MPa,
(6) concentrated extract is placed under ultrasonic ultraviolet sterilization;
(7) adding quality in concentrated extract is concentrated extract cyclodextrin, is spray dried to extract powder;
(8) dry granulation, the granulate that sieves i.e. obtains Herba Dendrobii granule.
CN201610058426.1A 2016-01-28 2016-01-28 Dendrobium officinale granules and preparation method thereof Pending CN105725209A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106690011A (en) * 2016-12-06 2017-05-24 黄山市皖乡农业科技有限公司 Dendrobium candidum nutritious porridge and preparation method thereof
CN113080454A (en) * 2021-05-10 2021-07-09 皖西学院 Dendrobium huoshanense ginseng oral liquid and preparation process and application thereof
CN113827664A (en) * 2021-10-19 2021-12-24 广东轻工职业技术学院 Instant dendrobium officinale micro-particle powder electuary and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102988828A (en) * 2012-11-21 2013-03-27 光明食品集团云南石斛生物科技开发有限公司 Preparation method of dendrobium officinale granula
CN102988827A (en) * 2012-11-21 2013-03-27 光明食品集团云南石斛生物科技开发有限公司 Dendrobium officinale granula
CN104824108A (en) * 2015-05-12 2015-08-12 范瑾 Traditional Chinese medicinal cake for preventing and treating type 2 diabetes and preparation method of traditional Chinese medicinal cake

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102988828A (en) * 2012-11-21 2013-03-27 光明食品集团云南石斛生物科技开发有限公司 Preparation method of dendrobium officinale granula
CN102988827A (en) * 2012-11-21 2013-03-27 光明食品集团云南石斛生物科技开发有限公司 Dendrobium officinale granula
CN104824108A (en) * 2015-05-12 2015-08-12 范瑾 Traditional Chinese medicinal cake for preventing and treating type 2 diabetes and preparation method of traditional Chinese medicinal cake

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106690011A (en) * 2016-12-06 2017-05-24 黄山市皖乡农业科技有限公司 Dendrobium candidum nutritious porridge and preparation method thereof
CN113080454A (en) * 2021-05-10 2021-07-09 皖西学院 Dendrobium huoshanense ginseng oral liquid and preparation process and application thereof
CN113827664A (en) * 2021-10-19 2021-12-24 广东轻工职业技术学院 Instant dendrobium officinale micro-particle powder electuary and preparation method thereof

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Application publication date: 20160706