CN108795628A - A kind of health wine with blood circulation-promoting effect and preparation method thereof - Google Patents

A kind of health wine with blood circulation-promoting effect and preparation method thereof Download PDF

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Publication number
CN108795628A
CN108795628A CN201810649875.2A CN201810649875A CN108795628A CN 108795628 A CN108795628 A CN 108795628A CN 201810649875 A CN201810649875 A CN 201810649875A CN 108795628 A CN108795628 A CN 108795628A
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parts
blood circulation
health
ingredient
promoting effect
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不公告发明人
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Foshan Jucheng Biochemical Technology Research and Development Co Ltd
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Foshan Jucheng Biochemical Technology Research and Development Co Ltd
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12GWINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
    • C12G3/00Preparation of other alcoholic beverages
    • C12G3/02Preparation of other alcoholic beverages by fermentation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
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    • A61K33/26Iron; Compounds thereof
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
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    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
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    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/29Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/46Eucommiaceae (Eucommia family), e.g. hardy rubber tree
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/72Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725Ziziphus, e.g. jujube
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Abstract

The invention discloses a kind of health wine with blood circulation-promoting effect and preparation method thereof, by the way that medicinal material and mineral material containing blood circulation-promoting health function is added, the functions such as immune adjusting, promoting blood circulation hemostasis, anti-oxidant, anti-mutation are played to human body, beneficial to human health, wherein health wine with blood circulation-promoting effect is made of the raw material of following parts by weight:1000~1200 parts of major ingredient ingredient, 55~85 parts of Chinese medicine health-care ingredient, 5~15 parts of Himalayan mayapple fruit flavones, 8~16 parts of motherwort polysaccharide, 5~8 parts of rhizoma chuanxiong volatile oil, 0.002~0.01 part of pyritum rotundum.The present invention is combined the healthcare function in traditional Chinese medicine ingredients with the wine that people are willing to accept so that drinks conveniently and prevent various diseases.

Description

A kind of health wine with blood circulation-promoting effect and preparation method thereof
Technical field
The invention belongs to health liquor preparing technical fields, and in particular to a kind of health wine with blood circulation-promoting effect and preparation method thereof.
Background technology
With the enhancing that people realize health care, the health liquor containing various nutritions and with healthcare function is got over Paid attention to come more people, demand is growing.For thousands of years, Chinese medicine is always the health protection of Chinese nation's procreation existence God is trusted by the people dearly, and modern medicine study proves, containing there are many chemical composition in Chinese medicine, can rise respectively The functions such as, promoting blood circulation hemostasis immune to adjusting, anti-oxidant, anti-mutation.For example promoting blood circulation is the process for promoting qi and blood to restore healthy state, It is realized generally by drug or specific movement is borrowed around here, but this process is slow and drug also has certain pair to make With, therefore how to be combined the healthcare function in traditional Chinese medicine ingredients with the wine that people are willing to accept so that it drinks convenient and prevents each Kind disease, is a very meaningful project.
Chinese invention《A kind of clearing and activating the channels and collaterals health liquor》(number of patent application:CN201710355933.6 it is provided in) a kind of logical Through health wine with blood circulation-promoting effect, including:Dipsacus root, Radix Angelicae Sinensis, Poria cocos, Radix Codonopsis, structure Qi, jujube, Ramulus Taxilli, Rhizoma Chuanxiong, pueraria lobata, Radix Astragali, Huang Company, big Radix Ophiopogonis, Morinda officinalis, Rhizoma Et Radix Notopterygii, mulligatawny, muntjac are fine and soft.What is used is all Chinese medicinal herbs, can treat cervical vertebra, lumbar vertebrae, scapulohumeral periarthritis etc.. But since absorption of human body speed is slower, so health-care effect is also more slow.
Invention content
The purpose of the present invention is to provide a kind of health wine with blood circulation-promoting effect and preparation method thereof, addition contains blood circulation-promoting health function Medicinal material and mineral material, beneficial to absorption and health.
To achieve the goals above, the present invention is realized by following technical scheme:
A kind of health wine with blood circulation-promoting effect is made of the raw material of following parts by weight:1000~1200 parts of major ingredient ingredient, Chinese medicine health-care 55~85 parts of ingredient, 5~15 parts of Himalayan mayapple fruit flavones, 8~16 parts of motherwort polysaccharide, 5~8 parts of rhizoma chuanxiong volatile oil, pyritum rotundum 0.002 ~0.01 part.
Preferably, a kind of health wine with blood circulation-promoting effect is made of the raw material of following parts by weight:1100 parts of major ingredient ingredient, Chinese medicine are protected Strong 70 parts of ingredient, 10 parts of Himalayan mayapple fruit flavones, 12 parts of motherwort polysaccharide, 6.5 parts of rhizoma chuanxiong volatile oil, 0.006 part of pyritum rotundum.
A kind of health wine with blood circulation-promoting effect of the present invention, the major ingredient ingredient are made of the raw material of following parts by weight:Glutinous rice 1000~ 1500 parts, 150~180 parts of rice, 8~12 parts of asparagus, 10~15 parts of lotus leaf, 8~10 parts of petasites tatewakianus kitam, 7~12 parts of emblic, 10~12 parts of mulberry leaf, 10~12 parts of the fruit of Chinese wolfberry, 6~8 parts of green lemon, 10~14 parts of green tea, 9~15 parts of Jasmine;The Chinese medicine Health-care components are made of the raw material of following parts by weight:1~3 part of Radix Astragali, 1~3 part of Rhizoma Atractylodis Macrocephalae, 1~3 part of Poria cocos, SEMEN SINAPIS ALBAE 3~5 Part, 4~7 parts of Radix Angelicae Sinensis, 4~7 parts of sea-buckthorn, 2~4 parts of scouring rush, 3~5 parts of wolfberry leaf, 3~5 parts of fructus amomi, 1~2 part of Cortex Eucommiae, jujube 1 ~2 parts.
Preferably, the major ingredient ingredient is made of the raw material of following parts by weight:1125~1375 parts of glutinous rice, rice 157.5~172.5 parts, 9~11 parts of asparagus, 11.25~13.75 parts of lotus leaf, 8.5~9.5 parts of petasites tatewakianus kitam, emblic 8.25~ 10.75 parts, 10.5~11.5 parts of mulberry leaf, 10.5~11.5 parts of the fruit of Chinese wolfberry, 6.5~7.5 parts of green lemon, 11~13 parts of green tea, jasmine 10.5~13.5 parts of jasmine;The Chinese medicine health-care ingredient is made of the raw material of following parts by weight:1.5~2.5 parts of Radix Astragali, Rhizoma Atractylodis Macrocephalae 1.5~2.5 parts, 1.5~2.5 parts of Poria cocos, 3.5~4.5 parts of SEMEN SINAPIS ALBAE, 4.75~6.25 parts of Radix Angelicae Sinensis, 4.75~6.25 parts of sea-buckthorn, 2.5~3.5 parts of scouring rush, 3.5~4.5 parts of wolfberry leaf, 3.5~4.5 parts of fructus amomi, 1.25~1.75 parts of Cortex Eucommiae, jujube 1.25~ 1.75 part.
It is highly preferred that the major ingredient ingredient is made of the raw material of following parts by weight:1250 parts of glutinous rice, 165 parts of rice, dragon It must 10 parts of dish, 12.5 parts of lotus leaf, 9 parts of petasites tatewakianus kitam, 9.5 parts of emblic, 11 parts of mulberry leaf, 11 parts of the fruit of Chinese wolfberry, 7 parts of green lemon, green tea 12 parts, 12 parts of Jasmine;The Chinese medicine health-care ingredient is made of the raw material of following parts by weight:2 parts of Radix Astragali, 2 parts of Rhizoma Atractylodis Macrocephalae, Poria cocos 2 parts, 4 parts of SEMEN SINAPIS ALBAE, 5.5 parts of Radix Angelicae Sinensis, 5.5 parts of sea-buckthorn, 3 parts of scouring rush, 4 parts of wolfberry leaf, 4 parts of fructus amomi, 1.5 parts of Cortex Eucommiae, jujube 1.5 Part.
A kind of health wine with blood circulation-promoting effect of the present invention, the preparation method of the Himalayan mayapple fruit flavones are:Dry Himalayan mayapple fruit crushed 20 ~40 mesh sieve, and are extracted using the molten method of ultrasonic wave added alcohol, are 1 by solid-liquid ratio:35~45 be added 70% ethyl alcohol, Extracting temperature be 50~ 60 DEG C, ultrasonic frequency is 2000~3000Hz, 40~50min of extraction time, and extracting solution rotary evaporation is finally removed ethyl alcohol, It is freeze-dried up to Himalayan mayapple fruit flavones.
A kind of health wine with blood circulation-promoting effect of the present invention, the preparation method of the motherwort polysaccharide are:
A. it is 1 to weigh motherwort dry product powder by solid-liquid ratio:10~20 are added 25~35min of standing after distilled water, are placed in 28~32 DEG C of water-baths, with 75~80 DEG C of heating extractions, filter residue extracts 2 times repeatedly, every time 3~4h, and extracting solution merges, rotary evaporation To the 1/5~3/5 of original volume, the sealing of 1/20~1/10 absolute ethyl alcohol of former extracting liquid volume is added overnight, polysaccharide is obtained after suction filtration Crude product;
B. by polysaccharide crude water dissolution, add activated carbon in 75~80 DEG C of water-baths, filtered after stirring 30~40min, repeated It decolourizes to obtain polysaccharide crude product solution 2~3 times;
C. the chloroform of 1/5 volume of polysaccharide crude solution is added, adds the n-butanol for 1/5 volume for being equivalent to chloroform, it will Mixture acutely shakes 20~30min, then centrifuges 8~10min with 3000~5000r/min, and liquid separation removes water layer and solvent Albuminate between layer repeats 6~8 times, protein is removed, and drying is to get motherwort after constant temperature, stirring are condensed into paste Polysaccharide.
A kind of health wine with blood circulation-promoting effect of the present invention, the preparation method of the rhizoma chuanxiong volatile oil are:The tender plant of Rhizoma Chuanxiong children is ground into 2 ~5cm, then be placed in the ground conical flask of 25mL, distilled water, which is added, makes it submerge Rhizoma Chuanxiong 1~2cm of fragment, connects the water of 25mL Separator 1 is heated with the electric hot plate of adjustable voltage, and heating is gradually heated up with 5~9 DEG C/min, and maintenance fluidized state 3~ After cooling, the volatile oil that extraction obtains is poured out from upper port by 5min.
A kind of health wine with blood circulation-promoting effect of the present invention, the preparation method of the pyritum rotundum are:By natural pyritum rotundum wash clean postposition iron It in tank, is fired to and is popular in smokeless intense fire, be 1 by solid-liquid ratio:0.5~0.8 is added vinegar, and vinegar is quenched while hot, takes out, and drying is just ?.
The present invention prepares a kind of method of health wine with blood circulation-promoting effect, includes the following steps:
(1) it first adds water to cook Chinese medicine health-care ingredient to obtain decoction liquor, isolates the dregs of a decoction;
(2) add water to cook major ingredient ingredient, after cooling, 0.15~0.45% distiller's yeast is added, container is put into after stirring evenly In in 20~28 DEG C sealing and fermenting;
(3) after being sealed by fermentation 3~4d, decocting for Chinese herbal medicine liquid is added, stirs evenly, ferment;
After (4) 10~15d, it is 6.5~6.8 to adjust pH, continues to ferment;
After (5) 15~20d, dietary alkali is added, it is 7.5~7.8 to adjust pH value, continues to ferment;
After (6) 15~20d, Wine blending liquid pH value is neutrality, squeezes to obtain wine liquid, using refined filtration to obtain the final product.
A kind of health wine with blood circulation-promoting effect prepared using the method for the invention is as a result as follows through examining:
Sense organ, for sample without precipitation, smell and flavour are normal.
Methanol, g/100mL, < 0.02
Fusel oil (in terms of isobutanol and isoamyl alcohol), g/100mL, 0.18
Cyanide, mg/L, < 0.15
Lead (in terms of Pb), mg/L < 0.25
Manganese (in terms of Mn), mg/L < 0.49
The above item-test result meets national Spirit and liqueur hygiene standard (GB2757-81).
The related introduction of the part raw material of the present invention is as follows:
Himalayan mayapple fruit flavones:It is derived from the dry mature fruit of Berberidaceae plant Chinese podophyllum root, has effects that promoting blood circulation for regulating menstruation, is used for The multiple gynecologicals such as blood stasis, difficult labour, stillborn foetus, mazischesis disease, is known as specially controlling the special efficacy Tibetan medicine of gynaecological disease, in Himalayan mayapple fruit Isoamylene radical chromocor has the multiple biological activities such as anti-oxidant, antibacterial, anti-inflammatory, promoting blood circulation.
Rhizoma chuanxiong volatile oil:The umbrella section type plant Rhizoma Chuanxiong of being derived from property pungent-warm, function wind-expelling pain-stopping, blood-activating and qi-promoting, active constituent Cardiovascular and cerebrovascular can be effectively expanded, and increases its blood flow, prevents coronary artery and aorta spasm, sedation and analgesia from inhibiting blood small Plate aggregation, hepatic fibrosis hyperplasia, oxygen radical release, release smooth muscle spasm etc..
Motherwort polysaccharide:It is taken from the fresh of labiate motherwort or dryly upper herb, acrid flavour, bitter, property are micro- It is cold.The thoughts of returning home, liver, bladder warp, have promoting blood circulation for regulating menstruation, inducing diuresis to remove edema, it is clearing heat and detoxicating the effect of.Motherwort polysaccharide isoreactivity substance has There is thrombolysis, anti-freezing, lipid-loweringing, reducing blood viscosity, drop erythrocyte aggregation, inhibits platelet aggregation, improves microcirculation, Green Tea Extract and subtract All multiactions of few intracellular calcium overload etc., additionally have improve immunity, hypoglycemic, reducing blood lipid, it is anti-oxidant, antitumor, The multiple biological activities such as antiviral, anti-infective, anti-radiation, anti-aging, antiallergy.
Pyritum rotundum:It is sweet in flavor, it is cold in nature, enter pericardium, Liver Channel, there is relieving convulsion and calming the nerves, analgesic therapy effect of stopping blooding cures mainly palpitaition, frightened epilepsy, intestines Wind bloody flux, stomachache, ulcerative carbuncle pyogenic infections, skeletal pain.
The present invention has following advantageous effect:
The present invention uses edible wild herbs and Chinese medicine health-care ingredient for raw material, has clearing heat and detoxicating, qi and activate blood circulation, anti-oxidant, anti-prominent The functions such as change, without side-effects, long-term drinking is good for health, promotes longevity.
Himalayan mayapple fruit flavones, motherwort polysaccharide, rhizoma chuanxiong volatile oil, pyritum rotundum is added in the present invention, and health liquor is made to live with heat-clearing Blood function is suitable for city white collar sub-health state person and drinks, can prevent disease.
Specific implementation mode
In order to make the technical means, the creative features, the aims and the efficiencies achieved by the present invention be easy to understand, tie below Specific embodiment is closed, the present invention is further explained.
Embodiment 1
A kind of health wine with blood circulation-promoting effect is made of the raw material of following parts by weight:1100 parts of major ingredient ingredient, Chinese medicine health-care ingredient 70 Part, 10 parts of Himalayan mayapple fruit flavones, 12 parts of motherwort polysaccharide, 6.5 parts of rhizoma chuanxiong volatile oil, 0.006 part of pyritum rotundum.
A kind of health wine with blood circulation-promoting effect of the present embodiment, the major ingredient ingredient are made of the raw material of following parts by weight:Glutinous rice 1250 Part, 165 parts of rice, 10 parts of asparagus, 12.5 parts of lotus leaf, 9 parts of petasites tatewakianus kitam, 9.5 parts of emblic, 11 parts of mulberry leaf, 11 parts of the fruit of Chinese wolfberry, 7 parts of green lemon, 12 parts of green tea, 12 parts of Jasmine;The Chinese medicine health-care ingredient is made of the raw material of following parts by weight:Radix Astragali 2 Part, 2 parts of Rhizoma Atractylodis Macrocephalae, 2 parts of Poria cocos, 4 parts of SEMEN SINAPIS ALBAE, 5.5 parts of Radix Angelicae Sinensis, 5.5 parts of sea-buckthorn, 3 parts of scouring rush, 4 parts of wolfberry leaf, 4 parts of fructus amomi, Du Secondary 1.5 parts, 1.5 parts of jujube.
The preparation method of a kind of health wine with blood circulation-promoting effect of the present embodiment, the Himalayan mayapple fruit flavones is:Dry Himalayan mayapple fruit crushed 30 mesh sieve, and are extracted using the molten method of ultrasonic wave added alcohol, are 1 by solid-liquid ratio:40 are added 70% ethyl alcohol, and Extracting temperature is 55 DEG C, ultrasound Wave frequency rate is 2500Hz, extraction time 45min, and extracting solution rotary evaporation is finally removed ethyl alcohol, is freeze-dried up to Himalayan mayapple fruit Flavones.
The preparation method of a kind of health wine with blood circulation-promoting effect of the present embodiment, the motherwort polysaccharide is:
A. it is 1 to weigh motherwort dry product powder by solid-liquid ratio:30min is stood after 15 addition distilled water, is placed in 30 DEG C of water-baths, With 77.5 DEG C of heating extractions, filter residue extracts 2 times, each 3.5h repeatedly, and extracting solution merges, and the 2/5 of rotary evaporation to original volume, add Enter the sealing of 1/15 absolute ethyl alcohol of former extracting liquid volume overnight, polysaccharide crude is obtained after suction filtration;
B. by polysaccharide crude water dissolution, add activated carbon in 77.5 DEG C of water-baths, filtered after stirring 35min, repeat decoloration 2 times Obtain polysaccharide crude product solution;
C. the chloroform of 1/5 volume of polysaccharide crude solution is added, adds the n-butanol for 1/5 volume for being equivalent to chloroform, it will Mixture acutely shakes 25min, then centrifuges 9min with 4000r/min, and liquid separation removes the denaturation egg between water layer and solvent layer In vain, it is repeated 7 times, protein is removed, drying is to get motherwort polysaccharide after constant temperature, stirring are condensed into paste.
A kind of health wine with blood circulation-promoting effect of the present embodiment, the preparation method of the rhizoma chuanxiong volatile oil are:The tender plant of Rhizoma Chuanxiong children is crushed It at 3.5cm, then is placed in the ground conical flask of 25mL, distilled water, which is added, makes it submerge Rhizoma Chuanxiong fragment 1.5cm, connects the water of 25mL Separator 1, is heated with the electric hot plate of adjustable voltage, and heating is gradually heated up with 7 DEG C/min, maintains fluidized state 4min, cooling Afterwards, the volatile oil that extraction obtains is poured out from upper port.
A kind of health wine with blood circulation-promoting effect of the present embodiment, the preparation method of the pyritum rotundum are:By natural pyritum rotundum wash clean postposition It in iron flask, is fired to and is popular in smokeless intense fire, be 1 by solid-liquid ratio:0.65 is added vinegar, and vinegar is quenched while hot, takes out, dry just to obtain.
The present embodiment prepares a kind of method of health wine with blood circulation-promoting effect, includes the following steps:
(1) it first adds water to cook Chinese medicine health-care ingredient to obtain decoction liquor, isolates the dregs of a decoction;
(2) add water to cook major ingredient ingredient, after cooling, 0.3% distiller's yeast is added, is put into after stirring evenly in container in 24 DEG C It is sealed by fermentation;
(3) after being sealed by fermentation 3.5d, decocting for Chinese herbal medicine liquid is added, stirs evenly, ferment;
(4) after 12.5d, it is 6.6 to adjust pH, continues to ferment;
(5) after 17.5d, dietary alkali is added, it is 7.7 to adjust pH value, continues to ferment;
(6) after 17.5d, Wine blending liquid pH value is neutrality, squeezes to obtain wine liquid, using refined filtration to obtain the final product.
A kind of health wine with blood circulation-promoting effect prepared using the present embodiment the method is as a result as follows through examining:
Sense organ, for sample without precipitation, smell and flavour are normal.
Methanol, g/100mL, < 0.02
Fusel oil (in terms of isobutanol and isoamyl alcohol), g/100mL, 0.18
Cyanide, mg/L, < 0.15
Lead (in terms of Pb), mg/L < 0.25
Manganese (in terms of Mn), mg/L < 0.49
The above item-test result meets national Spirit and liqueur hygiene standard (GB2757-81).
Embodiment 2
A kind of health wine with blood circulation-promoting effect is made of the raw material of following parts by weight:1000 parts of major ingredient ingredient, Chinese medicine health-care ingredient 55 Part, 5 parts of Himalayan mayapple fruit flavones, 8 parts of motherwort polysaccharide, 5 parts of rhizoma chuanxiong volatile oil, 0.002 part of pyritum rotundum.
A kind of health wine with blood circulation-promoting effect of the present embodiment, the major ingredient ingredient are made of the raw material of following parts by weight:Glutinous rice 1000 Part, 150 parts of rice, 8 parts of asparagus, 10 parts of lotus leaf, 8 parts of petasites tatewakianus kitam, 7 parts of emblic, 10 parts of mulberry leaf, 10 parts of the fruit of Chinese wolfberry, green lemon 6 parts of lemon, 10 parts of green tea, 9 parts of Jasmine;The Chinese medicine health-care ingredient is made of the raw material of following parts by weight:It is 1 part of Radix Astragali, white It is 1 part of art, 1 part of Poria cocos, 3 parts of SEMEN SINAPIS ALBAE, 4 parts of Radix Angelicae Sinensis, 4 parts of sea-buckthorn, 2 parts of scouring rush, 3 parts of wolfberry leaf, 3 parts of fructus amomi, 1 part of Cortex Eucommiae, red 1 part of jujube.
The preparation method of a kind of health wine with blood circulation-promoting effect of the present embodiment, the Himalayan mayapple fruit flavones is:Dry Himalayan mayapple fruit crushed 20 mesh sieve, and are extracted using the molten method of ultrasonic wave added alcohol, are 1 by solid-liquid ratio:35 are added 70% ethyl alcohol, and Extracting temperature is 50 DEG C, ultrasound Wave frequency rate is 2000Hz, extraction time 40min, and extracting solution rotary evaporation is finally removed ethyl alcohol, is freeze-dried up to Himalayan mayapple fruit Flavones.
The preparation method of a kind of health wine with blood circulation-promoting effect of the present embodiment, the motherwort polysaccharide is:
A. it is 1 to weigh motherwort dry product powder by solid-liquid ratio:25min is stood after 10 addition distilled water, is placed in 28 DEG C of water-baths, With 75 DEG C of heating extractions, filter residue extracts 2 times, each 3h repeatedly, and extracting solution merges, and the 1/5 of rotary evaporation to original volume, it is added former The sealing of 1/20 absolute ethyl alcohol of extracting liquid volume overnight, obtains polysaccharide crude after suction filtration;
B. by polysaccharide crude water dissolution, add activated carbon in 75 DEG C of water-baths, filtered after stirring 30min, repeat to decolourize 2 times Polysaccharide crude solution;
C. the chloroform of 1/5 volume of polysaccharide crude solution is added, adds the n-butanol for 1/5 volume for being equivalent to chloroform, it will Mixture acutely shakes 20min, then centrifuges 8min with 3000r/min, and liquid separation removes the denaturation egg between water layer and solvent layer In vain, it is repeated 6 times, protein is removed, drying is to get motherwort polysaccharide after constant temperature, stirring are condensed into paste.
A kind of health wine with blood circulation-promoting effect of the present embodiment, the preparation method of the rhizoma chuanxiong volatile oil are:The tender plant of Rhizoma Chuanxiong children is crushed It at 2cm, then is placed in the ground conical flask of 25mL, distilled water, which is added, makes it submerge Rhizoma Chuanxiong fragment 1cm, connects the water separation of 25mL Device 1, is heated with the electric hot plate of adjustable voltage, and heating is gradually heated up with 5 DEG C/min, maintains fluidized state 3min, after cooling, from Upper port pours out the volatile oil that extraction obtains.
A kind of health wine with blood circulation-promoting effect of the present embodiment, the preparation method of the pyritum rotundum are:By natural pyritum rotundum wash clean postposition It in iron flask, is fired to and is popular in smokeless intense fire, be 1 by solid-liquid ratio:0.5 is added vinegar, and vinegar is quenched while hot, takes out, dry just to obtain.
The present embodiment prepares a kind of method of health wine with blood circulation-promoting effect, includes the following steps:
(1) it first adds water to cook Chinese medicine health-care ingredient to obtain decoction liquor, isolates the dregs of a decoction;
(2) add water to cook major ingredient ingredient, after cooling, 0.15% distiller's yeast is added, is put into after stirring evenly in container in 20 DEG C be sealed by fermentation;
(3) after being sealed by fermentation 3d, decocting for Chinese herbal medicine liquid is added, stirs evenly, ferment;
(4) after 10d, it is 6.5 to adjust pH, continues to ferment;
(5) after 15d, dietary alkali is added, it is 7.5 to adjust pH value, continues to ferment;
(6) after 15d, Wine blending liquid pH value is neutrality, squeezes to obtain wine liquid, using refined filtration to obtain the final product.
A kind of health wine with blood circulation-promoting effect prepared using the present embodiment the method is as a result as follows through examining:
Sense organ, for sample without precipitation, smell and flavour are normal.
Methanol, g/100mL, < 0.02
Fusel oil (in terms of isobutanol and isoamyl alcohol), g/100mL, 0.18
Cyanide, mg/L, < 0.15
Lead (in terms of Pb), mg/L < 0.25
Manganese (in terms of Mn), mg/L < 0.49
The above item-test result meets national Spirit and liqueur hygiene standard (GB2757-81).
Embodiment 3
A kind of health wine with blood circulation-promoting effect is made of the raw material of following parts by weight:1200 parts of major ingredient ingredient, Chinese medicine health-care ingredient 85 Part, 15 parts of Himalayan mayapple fruit flavones, 16 parts of motherwort polysaccharide, 8 parts of rhizoma chuanxiong volatile oil, 0.01 part of pyritum rotundum.
A kind of health wine with blood circulation-promoting effect of the present embodiment, the major ingredient ingredient are made of the raw material of following parts by weight:Glutinous rice 1500 Part, 180 parts of rice, 12 parts of asparagus, 15 parts of lotus leaf, 10 parts of petasites tatewakianus kitam, 12 parts of emblic, 12 parts of mulberry leaf, 12 parts of the fruit of Chinese wolfberry, blueness 8 parts of lemon, 14 parts of green tea, 15 parts of Jasmine;The Chinese medicine health-care ingredient is made of the raw material of following parts by weight:3 parts of Radix Astragali, 3 parts of Rhizoma Atractylodis Macrocephalae, 3 parts of Poria cocos, 5 parts of SEMEN SINAPIS ALBAE, 7 parts of Radix Angelicae Sinensis, 7 parts of sea-buckthorn, 4 parts of scouring rush, 5 parts of wolfberry leaf, 5 parts of fructus amomi, 2 parts of Cortex Eucommiae, 2 parts of jujube.
The preparation method of a kind of health wine with blood circulation-promoting effect of the present embodiment, the Himalayan mayapple fruit flavones is:Dry Himalayan mayapple fruit crushed 40 mesh sieve, and are extracted using the molten method of ultrasonic wave added alcohol, are 1 by solid-liquid ratio:45 are added 70% ethyl alcohol, and Extracting temperature is 60 DEG C, ultrasound Wave frequency rate is 3000Hz, extraction time 50min, and extracting solution rotary evaporation is finally removed ethyl alcohol, is freeze-dried up to Himalayan mayapple fruit Flavones.
The preparation method of a kind of health wine with blood circulation-promoting effect of the present embodiment, the motherwort polysaccharide is:
A. it is 1 to weigh motherwort dry product powder by solid-liquid ratio:35min is stood after 20 addition distilled water, is placed in 32 DEG C of water-baths, With 80 DEG C of heating extractions, filter residue extracts 2 times, each 4h repeatedly, and extracting solution merges, and the 3/5 of rotary evaporation to original volume, it is added former The sealing of 1/10 absolute ethyl alcohol of extracting liquid volume overnight, obtains polysaccharide crude after suction filtration;
B. by polysaccharide crude water dissolution, add activated carbon in 80 DEG C of water-baths, filtered after stirring 40min, repeat to decolourize 3 times Polysaccharide crude solution;
C. the chloroform of 1/5 volume of polysaccharide crude solution is added, adds the n-butanol for 1/5 volume for being equivalent to chloroform, it will Mixture acutely shakes 30min, then centrifuges 10min with 5000r/min, and liquid separation removes the denaturation egg between water layer and solvent layer In vain, it is repeated 8 times, protein is removed, drying is to get motherwort polysaccharide after constant temperature, stirring are condensed into paste.
A kind of health wine with blood circulation-promoting effect of the present embodiment, the preparation method of the rhizoma chuanxiong volatile oil are:The tender plant of Rhizoma Chuanxiong children is crushed It at 5cm, then is placed in the ground conical flask of 25mL, distilled water, which is added, makes it submerge Rhizoma Chuanxiong fragment 2cm, connects the water separation of 25mL Device 1, is heated with the electric hot plate of adjustable voltage, and heating is gradually heated up with 9 DEG C/min, maintains fluidized state 5min, after cooling, from Upper port pours out the volatile oil that extraction obtains.
A kind of health wine with blood circulation-promoting effect of the present embodiment, the preparation method of the pyritum rotundum are:By natural pyritum rotundum wash clean postposition It in iron flask, is fired to and is popular in smokeless intense fire, be 1 by solid-liquid ratio:0.8 is added vinegar, and vinegar is quenched while hot, takes out, dry just to obtain.
The present embodiment prepares a kind of method of health wine with blood circulation-promoting effect, includes the following steps:
(1) it first adds water to cook Chinese medicine health-care ingredient to obtain decoction liquor, isolates the dregs of a decoction;
(2) add water to cook major ingredient ingredient, after cooling, 0.45% distiller's yeast is added, is put into after stirring evenly in container in 28 DEG C be sealed by fermentation;
(3) after being sealed by fermentation 4d, decocting for Chinese herbal medicine liquid is added, stirs evenly, ferment;
(4) after 15d, it is 6.8 to adjust pH, continues to ferment;
(5) after 20d, dietary alkali is added, it is 7.8 to adjust pH value, continues to ferment;
(6) after 20d, Wine blending liquid pH value is neutrality, squeezes to obtain wine liquid, using refined filtration to obtain the final product.
A kind of health wine with blood circulation-promoting effect prepared using the present embodiment the method is as a result as follows through examining:
Sense organ, for sample without precipitation, smell and flavour are normal.
Methanol, g/100mL, < 0.02
Fusel oil (in terms of isobutanol and isoamyl alcohol), g/100mL, 0.18
Cyanide, mg/L, < 0.15
Lead (in terms of Pb), mg/L < 0.25
Manganese (in terms of Mn), mg/L < 0.49
The above item-test result meets national Spirit and liqueur hygiene standard (GB2757-81).
Embodiment 4
A kind of health wine with blood circulation-promoting effect is made of the raw material of following parts by weight:1000 parts of major ingredient ingredient, Chinese medicine health-care ingredient 85 Part, 5 parts of Himalayan mayapple fruit flavones, 16 parts of motherwort polysaccharide, 5 parts of rhizoma chuanxiong volatile oil, 0.01 part of pyritum rotundum.
A kind of health wine with blood circulation-promoting effect of the present embodiment, the major ingredient ingredient are made of the raw material of following parts by weight:Glutinous rice 1125 Part, 157.5 parts of rice, 9 parts of asparagus, 11.25 parts of lotus leaf, 8.5 parts of petasites tatewakianus kitam, 8.25 parts of emblic, 10.5 parts of mulberry leaf, matrimony vine 10.5 parts of son, 6.5 parts of green lemon, 11 parts of green tea, 10.5 parts of Jasmine;The Chinese medicine health-care ingredient by following parts by weight former material Material composition:1.5 parts of Radix Astragali, 1.5 parts of Rhizoma Atractylodis Macrocephalae, 1.5 parts of Poria cocos, 3.5 parts of SEMEN SINAPIS ALBAE, 4.75 parts of Radix Angelicae Sinensis, 4.75 parts of sea-buckthorn, scouring rush 2.5 parts, 3.5 parts of wolfberry leaf, 3.5 parts of fructus amomi, 1.25 parts of Cortex Eucommiae, 1.25 parts of jujube.
The preparation method of a kind of health wine with blood circulation-promoting effect of the present embodiment, the Himalayan mayapple fruit flavones is:Dry Himalayan mayapple fruit crushed 25 mesh sieve, and are extracted using the molten method of ultrasonic wave added alcohol, are 1 by solid-liquid ratio:37.5 are added 70% ethyl alcohol, and Extracting temperature is 52.5 DEG C, Ultrasonic frequency is 2250Hz, extraction time 42.5min, and extracting solution rotary evaporation is finally removed ethyl alcohol, is freeze-dried to obtain the final product Himalayan mayapple fruit flavones.
The preparation method of a kind of health wine with blood circulation-promoting effect of the present embodiment, the motherwort polysaccharide is:
A. it is 1 to weigh motherwort dry product powder by solid-liquid ratio:27.5min is stood after 12.5 addition distilled water, is placed in 29 DEG C Water-bath, with 76 DEG C of heating extractions, filter residue extracts 2 times, each 3.5h repeatedly, and extracting solution merges, and the 3/ of rotary evaporation to original volume 5, the sealing of 1/20 absolute ethyl alcohol of former extracting liquid volume is added overnight, polysaccharide crude is obtained after suction filtration;
B. by polysaccharide crude water dissolution, add activated carbon in 76 DEG C of water-baths, filtered after stirring 32.5min, repeat decoloration 3 times Obtain polysaccharide crude product solution;
C. the chloroform of 1/5 volume of polysaccharide crude solution is added, adds the n-butanol for 1/5 volume for being equivalent to chloroform, it will Mixture acutely shakes 22.5min, then centrifuges 8.5min with 3500r/min, and liquid separation removes the change between water layer and solvent layer Property albumen, be repeated 7 times, protein removed, constant temperature, stirring are condensed into after paste drying to get motherwort polysaccharide.
A kind of health wine with blood circulation-promoting effect of the present embodiment, the preparation method of the rhizoma chuanxiong volatile oil are:The tender plant of Rhizoma Chuanxiong children is crushed It at 3cm, then is placed in the ground conical flask of 25mL, distilled water, which is added, makes it submerge Rhizoma Chuanxiong fragment 1.5cm, connects the moisture of 25mL It 1 from device, is heated with the electric hot plate of adjustable voltage, heating is gradually heated up with 6 DEG C/min, maintain fluidized state 3.5min, it is cooling Afterwards, the volatile oil that extraction obtains is poured out from upper port.
A kind of health wine with blood circulation-promoting effect of the present embodiment, the preparation method of the pyritum rotundum are:By natural pyritum rotundum wash clean postposition It in iron flask, is fired to and is popular in smokeless intense fire, be 1 by solid-liquid ratio:0.6 is added vinegar, and vinegar is quenched while hot, takes out, dry just to obtain.
The present embodiment prepares a kind of method of health wine with blood circulation-promoting effect, includes the following steps:
(1) it first adds water to cook Chinese medicine health-care ingredient to obtain decoction liquor, isolates the dregs of a decoction;
(2) add water to cook major ingredient ingredient, after cooling, 0.23% distiller's yeast is added, is put into after stirring evenly in container in 22 DEG C be sealed by fermentation;
(3) after being sealed by fermentation 3.5d, decocting for Chinese herbal medicine liquid is added, stirs evenly, ferment;
(4) after 11d, it is 6.7 to adjust pH, continues to ferment;
(5) after 16d, dietary alkali is added, it is 7.6 to adjust pH value, continues to ferment;
(6) after 16d, Wine blending liquid pH value is neutrality, squeezes to obtain wine liquid, using refined filtration to obtain the final product.
A kind of health wine with blood circulation-promoting effect prepared using the present embodiment the method is as a result as follows through examining:
Sense organ, for sample without precipitation, smell and flavour are normal.
Methanol, g/100mL, < 0.02
Fusel oil (in terms of isobutanol and isoamyl alcohol), g/100mL, 0.18
Cyanide, mg/L, < 0.15
Lead (in terms of Pb), mg/L < 0.25
Manganese (in terms of Mn), mg/L < 0.49
The above item-test result meets national Spirit and liqueur hygiene standard (GB2757-81).
Embodiment 5
A kind of health wine with blood circulation-promoting effect is made of the raw material of following parts by weight:1200 parts of major ingredient ingredient, Chinese medicine health-care ingredient 55 Part, 15 parts of Himalayan mayapple fruit flavones, 8 parts of motherwort polysaccharide, 8 parts of rhizoma chuanxiong volatile oil, 0.002 part of pyritum rotundum.
A kind of health wine with blood circulation-promoting effect of the present embodiment, the major ingredient ingredient are made of the raw material of following parts by weight:Glutinous rice 1375 Part, 172.5 parts of rice, 11 parts of asparagus, 13.75 parts of lotus leaf, 9.5 parts of petasites tatewakianus kitam, 10.75 parts of emblic, 11.5 parts of mulberry leaf, Chinese holly 11.5 parts of matrimony vine, 7.5 parts of green lemon, 13 parts of green tea, 13.5 parts of Jasmine;The Chinese medicine health-care ingredient by following parts by weight original Material forms:2.5 parts of Radix Astragali, 2.5 parts of Rhizoma Atractylodis Macrocephalae, 2.5 parts of Poria cocos, 4.5 parts of SEMEN SINAPIS ALBAE, 6.25 parts of Radix Angelicae Sinensis, 6.25 parts of sea-buckthorn, scouring rush 3.5 parts, 4.5 parts of wolfberry leaf, 4.5 parts of fructus amomi, 1.75 parts of Cortex Eucommiae, 1.75 parts of jujube.
The preparation method of a kind of health wine with blood circulation-promoting effect of the present embodiment, the Himalayan mayapple fruit flavones is:Dry Himalayan mayapple fruit crushed 35 mesh sieve, and are extracted using the molten method of ultrasonic wave added alcohol, are 1 by solid-liquid ratio:42.5 are added 70% ethyl alcohol, and Extracting temperature is 57.5 DEG C, Ultrasonic frequency is 2750Hz, extraction time 47.5min, and extracting solution rotary evaporation is finally removed ethyl alcohol, is freeze-dried to obtain the final product Himalayan mayapple fruit flavones.
The preparation method of a kind of health wine with blood circulation-promoting effect of the present embodiment, the motherwort polysaccharide is:
A. it is 1 to weigh motherwort dry product powder by solid-liquid ratio:32.5min is stood after 17.5 addition distilled water, is placed in 31 DEG C Water-bath, with 79 DEG C of heating extractions, filter residue extracts 2 times, each 3.5h repeatedly, and extracting solution merges, and the 1/ of rotary evaporation to original volume 5, the sealing of 1/10 absolute ethyl alcohol of former extracting liquid volume is added overnight, polysaccharide crude is obtained after suction filtration;
B. by polysaccharide crude water dissolution, add activated carbon in 78 DEG C of water-baths, filtered after stirring 37.5min, repeat decoloration 3 times Obtain polysaccharide crude product solution;
C. the chloroform of 1/5 volume of polysaccharide crude solution is added, adds the n-butanol for 1/5 volume for being equivalent to chloroform, it will Mixture acutely shakes 27.5min, then centrifuges 9.5min with 4500r/min, and liquid separation removes the change between water layer and solvent layer Property albumen, be repeated 7 times, protein removed, constant temperature, stirring are condensed into after paste drying to get motherwort polysaccharide.
A kind of health wine with blood circulation-promoting effect of the present embodiment, the preparation method of the rhizoma chuanxiong volatile oil are:The tender plant of Rhizoma Chuanxiong children is crushed It at 4cm, then is placed in the ground conical flask of 25mL, distilled water, which is added, makes it submerge Rhizoma Chuanxiong fragment 1.5cm, connects the moisture of 25mL It 1 from device, is heated with the electric hot plate of adjustable voltage, heating is gradually heated up with 8 DEG C/min, maintain fluidized state 4.5min, it is cooling Afterwards, the volatile oil that extraction obtains is poured out from upper port.
A kind of health wine with blood circulation-promoting effect of the present embodiment, the preparation method of the pyritum rotundum are:By natural pyritum rotundum wash clean postposition It in iron flask, is fired to and is popular in smokeless intense fire, be 1 by solid-liquid ratio:0.7 is added vinegar, and vinegar is quenched while hot, takes out, dry just to obtain.
The present embodiment prepares a kind of method of health wine with blood circulation-promoting effect, includes the following steps:
(1) it first adds water to cook Chinese medicine health-care ingredient to obtain decoction liquor, isolates the dregs of a decoction;
(2) add water to cook major ingredient ingredient, after cooling, 0.4% distiller's yeast is added, is put into after stirring evenly in container in 26 DEG C It is sealed by fermentation;
(3) after being sealed by fermentation 3.5d, decocting for Chinese herbal medicine liquid is added, stirs evenly, ferment;
(4) after 14d, it is 6.7 to adjust pH, continues to ferment;
(5) after 19d, dietary alkali is added, it is 7.7 to adjust pH value, continues to ferment;
(6) after 19d, Wine blending liquid pH value is neutrality, squeezes to obtain wine liquid, using refined filtration to obtain the final product.
A kind of health wine with blood circulation-promoting effect prepared using the present embodiment the method is as a result as follows through examining:
Sense organ, for sample without precipitation, smell and flavour are normal.
Methanol, g/100mL, < 0.02
Fusel oil (in terms of isobutanol and isoamyl alcohol), g/100mL, 0.18
Cyanide, mg/L, < 0.15
Lead (in terms of Pb), mg/L < 0.25
Manganese (in terms of Mn), mg/L < 0.49
The above item-test result meets national Spirit and liqueur hygiene standard (GB2757-81).
Several embodiments of the invention above described embodiment only expresses, the description thereof is more specific and detailed, but simultaneously Cannot the limitation to the scope of the claims of the present invention therefore be interpreted as.It should be pointed out that for those of ordinary skill in the art For, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to the guarantor of the present invention Protect range.

Claims (10)

1. a kind of health wine with blood circulation-promoting effect, which is characterized in that be made of the raw material of following parts by weight:Major ingredient ingredient 1000~1200 Part, 55~85 parts of Chinese medicine health-care ingredient, 5~15 parts of Himalayan mayapple fruit flavones, 8~16 parts of motherwort polysaccharide, 5~8 parts of rhizoma chuanxiong volatile oil, 0.002~0.01 part of pyritum rotundum.
2. a kind of health wine with blood circulation-promoting effect according to claim 1, which is characterized in that be made of the raw material of following parts by weight: 1100 parts of major ingredient ingredient, 70 parts of Chinese medicine health-care ingredient, 10 parts of Himalayan mayapple fruit flavones, 12 parts of motherwort polysaccharide, rhizoma chuanxiong volatile oil 6.5 Part, 0.006 part of pyritum rotundum.
3. a kind of health wine with blood circulation-promoting effect according to claim 1 or 2, which is characterized in that the major ingredient ingredient is by following weight The raw material composition of part:1000~1500 parts of glutinous rice, 150~180 parts of rice, 8~12 parts of asparagus, 10~15 parts of lotus leaf, mountain Reveal 8~10 parts of dish, 7~12 parts of emblic, 10~12 parts of mulberry leaf, 10~12 parts of the fruit of Chinese wolfberry, 6~8 parts of green lemon, green tea 10~14 Part, 9~15 parts of Jasmine;The Chinese medicine health-care ingredient is made of the raw material of following parts by weight:1~3 part of Radix Astragali, Rhizoma Atractylodis Macrocephalae 1~3 Part, 1~3 part of Poria cocos, 3~5 parts of SEMEN SINAPIS ALBAE, 4~7 parts of Radix Angelicae Sinensis, 4~7 parts of sea-buckthorn, 2~4 parts of scouring rush, 3~5 parts of wolfberry leaf, fructus amomi 3~5 parts, 1~2 part of Cortex Eucommiae, 1~2 part of jujube.
4. a kind of health wine with blood circulation-promoting effect according to claim 3, which is characterized in that the major ingredient ingredient is by following parts by weight Raw material form:1125~1375 parts of glutinous rice, 157.5~172.5 parts of rice, 9~11 parts of asparagus, lotus leaf 11.25~13.75 Part, 8.5~9.5 parts of petasites tatewakianus kitam, 8.25~10.75 parts of emblic, 10.5~11.5 parts of mulberry leaf, 10.5~11.5 parts of the fruit of Chinese wolfberry, 6.5~7.5 parts of green lemon, 11~13 parts of green tea, 10.5~13.5 parts of Jasmine;The Chinese medicine health-care ingredient is by following parts by weight Raw material composition:1.5~2.5 parts of Radix Astragali, 1.5~2.5 parts of Rhizoma Atractylodis Macrocephalae, 1.5~2.5 parts of Poria cocos, 3.5~4.5 parts of SEMEN SINAPIS ALBAE, when Return 4.75~6.25 parts, 4.75~6.25 parts of sea-buckthorn, 2.5~3.5 parts of scouring rush, 3.5~4.5 parts of wolfberry leaf, fructus amomi 3.5~4.5 Part, 1.25~1.75 parts of Cortex Eucommiae, 1.25~1.75 parts of jujube.
5. a kind of health wine with blood circulation-promoting effect according to claim 4, which is characterized in that the major ingredient ingredient is by following parts by weight Raw material form:1250 parts of glutinous rice, 165 parts of rice, 10 parts of asparagus, 12.5 parts of lotus leaf, 9 parts of petasites tatewakianus kitam, 9.5 parts of emblic, 11 parts of mulberry leaf, 11 parts of the fruit of Chinese wolfberry, 7 parts of green lemon, 12 parts of green tea, 12 parts of Jasmine;The Chinese medicine health-care ingredient is by following weight The raw material composition of part:2 parts of Radix Astragali, 2 parts of Rhizoma Atractylodis Macrocephalae, 2 parts of Poria cocos, 4 parts of SEMEN SINAPIS ALBAE, 5.5 parts of Radix Angelicae Sinensis, 5.5 parts of sea-buckthorn, 3 parts of scouring rush, 4 parts of wolfberry leaf, 4 parts of fructus amomi, 1.5 parts of Cortex Eucommiae, 1.5 parts of jujube.
6. a kind of health wine with blood circulation-promoting effect according to claim 1 or 2, which is characterized in that the preparation side of the Himalayan mayapple fruit flavones Method is:Dry Himalayan mayapple fruit be crushed into 20~40 mesh sieve, extracted using the molten method of ultrasonic wave added alcohol, be 1 by solid-liquid ratio:35~45 add Enter 70% ethyl alcohol, Extracting temperature is 50~60 DEG C, and ultrasonic frequency is 2000~3000Hz, 40~50min of extraction time, finally Extracting solution rotary evaporation is removed into ethyl alcohol, is freeze-dried up to Himalayan mayapple fruit flavones.
7. a kind of health wine with blood circulation-promoting effect according to claim 1 or 2, which is characterized in that the preparation side of the motherwort polysaccharide Method is:
A. it is 1 to weigh motherwort dry product powder by solid-liquid ratio:10~20 distilled water are added after stand 25~35min, be placed in 28~ 32 DEG C of water-baths, with 75~80 DEG C of heating extractions, filter residue extracts 2 times repeatedly, every time 3~4h, and extracting solution merges, rotary evaporation to original The 1/5~3/5 of volume is added the sealing of 1/20~1/10 absolute ethyl alcohol of former extracting liquid volume overnight, polysaccharide crude is obtained after suction filtration;
B. by polysaccharide crude water dissolution, add activated carbon in 75~80 DEG C of water-baths, filtered after stirring 30~40min, repeat decoloration 2 ~3 times polysaccharide crude product solution;
C. the chloroform of 1/5 volume of polysaccharide crude solution is added, adds the n-butanol for 1/5 volume for being equivalent to chloroform, will mix Then the violent 20~30min of concussion of object centrifuges 8~10min with 3000~5000r/min, liquid separation remove water layer and solvent layer it Between albuminate, repeat 6~8 times, protein removed, it is more to get motherwort that constant temperature, stirring are condensed into drying after paste Sugar.
8. a kind of health wine with blood circulation-promoting effect according to claim 1 or 2, which is characterized in that the preparation side of the rhizoma chuanxiong volatile oil Method is:The tender plant of Rhizoma Chuanxiong children is ground into 2~5cm, then is placed in the ground conical flask of 25mL, distilled water, which is added, makes it submerge river Rhizome of chuanxiong 1~2cm of fragment connects the separator 1 of 25mL, is heated with the electric hot plate of adjustable voltage, is gradually added with 5~9 DEG C/min Heat heating maintains 3~5min of fluidized state, and after cooling, the volatile oil that extraction obtains is poured out from upper port.
9. a kind of health wine with blood circulation-promoting effect according to claim 1 or 2, which is characterized in that the preparation method of the pyritum rotundum is: It by natural pyritum rotundum wash clean postposition iron flask, is fired to and is popular in smokeless intense fire, be 1 by solid-liquid ratio:0.5~0.8 is added acid Vinegar, while hot vinegar quench, take out, it is dry just.
10. a kind of prepare such as a kind of method of health wine with blood circulation-promoting effect of claim 1~9 any one of them, which is characterized in that including Following steps:
(1) it first adds water to cook Chinese medicine health-care ingredient to obtain decoction liquor, isolates the dregs of a decoction;
(2) add water to cook major ingredient ingredient, after cooling, be added 0.15~0.45% distiller's yeast, be put into after stirring evenly in container in 20~28 DEG C of sealing and fermentings;
(3) after being sealed by fermentation 3~4d, decocting for Chinese herbal medicine liquid is added, stirs evenly, ferment;
After (4) 10~15d, it is 6.5~6.8 to adjust pH, continues to ferment;
After (5) 15~20d, dietary alkali is added, it is 7.5~7.8 to adjust pH value, continues to ferment;
After (6) 15~20d, Wine blending liquid pH value is neutrality, squeezes to obtain wine liquid, using refined filtration to obtain the final product.
CN201810649875.2A 2018-06-21 2018-06-21 A kind of health wine with blood circulation-promoting effect and preparation method thereof Withdrawn CN108795628A (en)

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