CN106389215A - Whitening lotion prepared from puncturevine caltrop fruit - Google Patents
Whitening lotion prepared from puncturevine caltrop fruit Download PDFInfo
- Publication number
- CN106389215A CN106389215A CN201610953913.4A CN201610953913A CN106389215A CN 106389215 A CN106389215 A CN 106389215A CN 201610953913 A CN201610953913 A CN 201610953913A CN 106389215 A CN106389215 A CN 106389215A
- Authority
- CN
- China
- Prior art keywords
- fructus tribuli
- whitening
- buddleoside
- caltrop fruit
- puncturevine caltrop
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses whitening lotion prepared from puncturevine caltrop fruit. Effective components of the whitening lotion comprise buddleoside, puncturevine caltrop fruit extract and substrates, wherein the weight ratio of the puncturevine caltrop fruit extract to the buddleoside is (10:1)-(20:1), the substrates comprise vitamin E magnesium phosphate, polyglyceryl-3 diisostearate, glycolic acid, linseed oil and hyaluronic acid. The puncturevine caltrop fruit extract is taken as the main raw material, the buddleoside and certain substrates are added, the cost is low, the puncturevine caltrop fruit extract is mixed with a small amount of buddleoside to have a good synergetic effect on whitening, and the whitening effect is improved substantially especially when the weight ratio of the puncturevine caltrop fruit extract to the buddleoside is (10:1)-(20:1).
Description
Technical field
The present invention relates to a kind of Fructus Tribuli whitening lotion, belong to cosmetic skin care product field.
Background technology
Astringent is referred to as by cosmetic water, toner/smoothing toner, astringent lotion, is a kind of cosmetics of transparent liquid, is applied to the table of skin
Face, for cleaning skin, keeping the health of skin.Cosmetic water, astringent lotion and toner/smoothing toner difference are not too big, cosmetic water, convergence
Water is more suitable for that weather is warmmer, compares the fuel-displaced weather of love on the face and uses, the season that toner/smoothing toner is more suitable for drying uses.Astringent exists
Acted the effect taken over from the past and set a new course for the future, the raising with people's quality of the life and people are to beautiful pursuit, astringent in basic skin protection
Kind class is more and more various.
Fructus Tribuli（Scientific name：Tribulus terrestris L.）Also known as Fructus Atriplicis Sibiricae, people in the wrong etc..Stem prostration, no hair, soft by length
Hair or long bristle.All parts of the country are distributed.It is born in sand ground, wasteland, hillside, the residential area ground such as nearby.Feedstuff can be made when blue or green fresh.Really
Be used as medicine can flat liver improving eyesight, dissipate be in fashion blood.Between fruit thorniness easy-adhesion domestic animal hair, damage coat quality.
Linarin (【English name】Buddleoside) 【No. CAS】480-36-4 have anti-aging effects, oxygen lack resistant function,
Anti- pessimal stimulation acts on, to body dual regulation, antifatigue effect, suppression blood glucose rise effect, toxicity and mutagenicity
The research of teratogenesis aspect, the impact to learning and memory.The current utilization for Fructus Tribuli extract and linarin is particularly in U.S.
The application of white astringent have not been reported.
Content of the invention
The problem existing for above-mentioned prior art, the present invention provides a kind of Fructus Tribuli whitening lotion, with low cost, whitening
Effect is good.
To achieve these goals, the technical solution used in the present invention is：Effective ingredient includes linarin, Fructus Tribuli is extracted
Thing, glycerol, according to weight ratio, the weight of described Fructus Tribuli extract and linarin is than 10:1-20:1.
Linarin 0.2%, Fructus Tribuli extract 4%, glycerol 5%, propylene glycol 3%, allantoin 2%, hydroxyethyl cellulose 0.8%, mountain
Pears, 2%, hyaluronate sodium 0.8% and water surplus are constituted.
The present invention, with Fructus Tribuli extract as primary raw material, adds linarin and some substrate, it is cheap, and Fructus Tribuli carries
Take thing to mix with a small amount of linarin and good synergy plays for whitening, particularly the weight of Fructus Tribuli extract and linarin
Amount compares 15:1, whitening effect increases substantially.
Specific embodiment
The invention will be further described below.、
Embodiment 1：
The processing technology of described Fructus Tribuli extract is 1) by the Fructus Tribuli after vacuum drying, pulverize in pulverizer and obtain Fructus Tribuli powder
End, Fructus Tribuli powder is placed in the extraction kettle of supercritical extraction, 2) supercritical CO 2 is used as solvent, concentration is 65% second
Alcohol does entrainer；3) adjust extraction kettle extracting pressure is controlled in 25～30MPa, temperature control at 45 DEG C, CO2 flow-control
In 9L/h, extraction time controls in 2h, obtains Fructus Tribuli extract.
It is respectively according to weight proportion：Linarin 0.2%, Fructus Tribuli extract 4%, glycerol 5%, propylene glycol 3%, allantoin 2%,
Hydroxyethyl cellulose 0.8%, Pyrusussuriensiss, 2%, hyaluronate sodium 0.8% and water surplus are constituted.
Embodiment 2
As embodiment 1 processing technology, difference is：Linarin 0.3%, Fructus Tribuli extract 4.5%, glycerol 5%, the third two
Alcohol 3%, allantoin 2%, hydroxyethyl cellulose 0.8%, Pyrusussuriensiss, 2%, hyaluronate sodium 0.8% and water surplus are constituted.
Embodiment 3
Fructus Tribuli extract with for linarin ratio be 10:1, both account for 5% at gross weight, and other include glycerol 5%, propylene glycol 3%, allantois
Element 2%, hydroxyethyl cellulose 0.8%, Pyrusussuriensiss, 2%, hyaluronate sodium 0.8% and water surplus are constituted.
Embodiment 4
Fructus Tribuli extract with for linarin ratio be 5:1, both account for 5% at gross weight, and other include glycerol 5%, propylene glycol 3%, allantoin
2%, hydroxyethyl cellulose 0.8%, Pyrusussuriensiss, 2%, hyaluronate sodium 0.8% and water surplus are constituted.
Embodiment 5
Fructus Tribuli extract with for linarin ratio be 2:1, both account for 5% at gross weight, and other include glycerol 5%, propylene glycol 3%, allantoin
2%, hydroxyethyl cellulose 0.8%, Pyrusussuriensiss, 2%, hyaluronate sodium 0.8% and water surplus are constituted.
Detection method：
Middle melanin genesis test in suppression mouse melanin cell.
By B16 mouse melanin tumor cell with 1 × 105The density of individual/ml is connected to the culture dish of a diameter of 9cm, at 37 DEG C
5%CO2Under conditions of cultivate 2 days, abandon supernatant, add the sample solution 18-22ml after filtration sterilization, be then incubated for 3 days, abandon
Supernatant, PBS washs, and every hole adds the trypsin solution peptic cell 3min of 0.5ml mass percent 0.2%, and every ware adds 2ml dimension
Hold liquid and terminate digestion. after piping and druming mixes, every kind of concentration is taken out 0.5ml and is made cell counting. remaining cell suspension with 2500r/min from
Heart 5min, abandons supernatant, adds NaoH solution in precipitation, and heating makes melanin dissolve, and selects the enzyme linked immunological of 490nm wavelength
Absorbance is surveyed on detector.
B16 cell suppression ratio=(1- (medicine hole absorbance+medicine hole cell density)+(control wells absorbance+right
According to hole cell density)) × 100%.
Middle melanin genesis test in suppression mouse melanin cell, result is as follows
A is Fructus Tribuli extract, and B is linarin,
Above-mentioned test result indicate that, Fructus Tribuli extract and linarin by a certain percentage (15：1) fusion each other have collaborative
Whitening effect, can effectively suppress melanin to generate, and effect is significant.And between other ratios, then have no synergism, whitening
DeGrain.
Claims (3)
1. a kind of Fructus Tribuli whitening lotion is it is characterised in that effective ingredient includes linarin, Fructus Tribuli extract, glycerol, and the third two
Alcohol, allantoin, hydroxyethyl cellulose, hyaluronate sodium and water surplus are constituted.
2. a kind of Fructus Tribuli whitening lotion according to claim 1 is it is characterised in that according to weight ratio, described Fructus Tribuli
The weight of extract and linarin is than 1:1-20:1.
3. a kind of Fructus Tribuli whitening lotion according to claim 1 it is characterised in that described inclusion linarin 0.2%,
Fructus Tribuli extract 4%, glycerol 5%, propylene glycol 3%, allantoin 2%, hydroxyethyl cellulose 0.8%, Pyrusussuriensiss, 2%, hyaluronate sodium 0.8%
Constitute with water surplus.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610953913.4A CN106389215A (en) | 2016-11-03 | 2016-11-03 | Whitening lotion prepared from puncturevine caltrop fruit |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610953913.4A CN106389215A (en) | 2016-11-03 | 2016-11-03 | Whitening lotion prepared from puncturevine caltrop fruit |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106389215A true CN106389215A (en) | 2017-02-15 |
Family
ID=58014411
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610953913.4A Pending CN106389215A (en) | 2016-11-03 | 2016-11-03 | Whitening lotion prepared from puncturevine caltrop fruit |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106389215A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107737059A (en) * | 2017-12-04 | 2018-02-27 | 刘晓冰 | A kind of centella whitening lotion |
| CN107822990A (en) * | 2017-12-04 | 2018-03-23 | 刘晓冰 | A kind of Sargent gloryvine whitening lotion |
-
2016
- 2016-11-03 CN CN201610953913.4A patent/CN106389215A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107737059A (en) * | 2017-12-04 | 2018-02-27 | 刘晓冰 | A kind of centella whitening lotion |
| CN107822990A (en) * | 2017-12-04 | 2018-03-23 | 刘晓冰 | A kind of Sargent gloryvine whitening lotion |
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| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20170215 |
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| WD01 | Invention patent application deemed withdrawn after publication |