CN106036879A - Healthcare food capable of relieving physical fatigue and making method thereof - Google Patents

Healthcare food capable of relieving physical fatigue and making method thereof Download PDF

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Publication number
CN106036879A
CN106036879A CN201610517366.5A CN201610517366A CN106036879A CN 106036879 A CN106036879 A CN 106036879A CN 201610517366 A CN201610517366 A CN 201610517366A CN 106036879 A CN106036879 A CN 106036879A
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China
Prior art keywords
parts
maltodextrin
health food
rhizoma polygonati
filtrate
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Inventor
乐智勇
彭晓辉
于向红
聂庆红
许冬瑾
马兴田
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GUANGDONG KANGMEI PHARMACEUTICAL RESEARCH INSTITUTE CO LTD
Kangmei (beijing) Pharmaceutical Research Institute Co Ltd
Kangmei Pharmaceutical Co Ltd
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GUANGDONG KANGMEI PHARMACEUTICAL RESEARCH INSTITUTE CO LTD
Kangmei (beijing) Pharmaceutical Research Institute Co Ltd
Kangmei Pharmaceutical Co Ltd
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Priority to CN201610517366.5A priority Critical patent/CN106036879A/en
Publication of CN106036879A publication Critical patent/CN106036879A/en
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

The invention relates to healthcare food capable of relieving physical fatigue and a making method thereof. The healthcare food is composed of, by weight, 150-350 parts of ginseng, 0-350 parts of wolfberry fruit, 0-300 parts of Rhizoma polygonati, 0-300 parts of Radix rehmanniae, 500-700 parts of maltodextrin and 0.5-1.5 parts of Aspartame. The healthcare food is reasonable in formulation, extensive in raw material source, nontoxic, harmless and exact in efficacy ingredient, has obvious efficacy of relieving physical fatigue and has same effect as classic qi-blood tonifying ancient formulations. The formulation is easy to be applied in large-scale production and suitable for commercial-scale production.

Description

A kind of health food for relieving physical fatigue and preparation method thereof
Technical field
The present invention relates to a kind of health food for relieving physical fatigue and preparation method thereof, belong to field of health care products.
Background technology
Along with the quickening of modern society's rhythm of life, people not only to bear study, work, the weight of the various aspects such as life Pressure, and owing to environmental pollution is day by day serious, many people are in " subhealth state " state, mainly show as susceptible fatigue etc..
Fatigue is a kind of natural phenomena, owing to work, learning tasks are heavy, caused by rhythm of life anxiety.In recent years, due to Tired induction sudden illness, causes existing disease condition to increase the weight of, and the example even threatening life gets more and more, people for The understanding of tired harm is the most deep.At present, tired main harm is concluded as " fatigue syndrome ", and this is a kind of with length Phase fatigue is the general syndrome of main performance.Modern medicine is shown experimentally that, " tired " does not develops into " tired comprehensive Disease " just take effective intervening measure, and custom of making the life better before, just can effectively alleviate the prestige of " fatigue syndrome " The side of body.
Physical fatigue disease has become as affects people's life, work and healthy big factors, and edible have alleviation The health food of physical fatigue function is necessary.Prior art has the health product of a lot of alleviating physical fatigue, but effect Inconspicuous, it is impossible to meet market demands.
Summary of the invention
In order to solve the inapparent problem of alleviating physical fatigue product effect on market, the invention provides a kind of alleviation body The significant health food of power fatigue effect.
One purpose of the present invention is to provide a kind of health food for relieving physical fatigue, its raw material be Radix Ginseng, Fructus Lycii, Rhizoma Polygonati, Radix Rehmanniae.This formula is reasonable, raw material sources are extensive, nontoxic, functional component is clear and definite, effect of alleviating physical fatigue Substantially, play the same tune on different musical instruments part with classical QI invigorating, ancient prescription of enriching blood.During this formula is readily deployed in big production simultaneously, it is suitable for business The production of change scale.
Another object of the present invention is to provide a kind of production efficiency high, and effect is notable, and material loss is low, energy-conserving and environment-protective, Energy consumption and low cost, the preparation method of technical process simple alleviating physical fatigue health food granule.
The purpose of the present invention is achieved through the following technical solutions:
The present invention provides a kind of health food for relieving physical fatigue, is composed of the following raw materials by weight:
Radix Ginseng 150~350 parts, Fructus Lycii 0~350 parts, Rhizoma Polygonati 0~300 parts, Radix Rehmanniae 0~300 parts, maltodextrin 500 ~700 parts and aspartame 0.5~1.5 parts.
On the basis of technique scheme, the present invention can also do following improvement.
Further, described health food, it is composed of the following raw materials by weight:
Radix Ginseng 320~350 parts, Fructus Lycii 190~210 parts, Radix Rehmanniae 200~300 parts, maltodextrin 620~700 parts and Aspartame 0.5~1.5 parts.
Further, described health food, it is composed of the following raw materials by weight:
Radix Ginseng 320~350 parts, Rhizoma Polygonati 190~210 parts, Radix Rehmanniae 200~300 parts, maltodextrin 620~700 parts and Ah This Ba Tian 0.5~1.5 parts.
Further, described health food, it is composed of the following raw materials by weight:
Radix Ginseng 200~250 parts, Fructus Lycii 200~250 parts, Rhizoma Polygonati 200~300 parts, Radix Rehmanniae 200~300 parts, Fructus Hordei Germinatus Dextrin 540~580 parts and aspartame 0.5~1.5 parts.
Further, described health food, it is composed of the following raw materials by weight:
Radix Ginseng 201 parts, Fructus Lycii 201 parts, Rhizoma Polygonati 268 parts, Radix Rehmanniae 268 parts, maltodextrin 555 parts and aspartame 1.072 part.
The present invention also provides for the preparation method of a kind of health food as above, including:
1) extract: Radix Ginseng, Fructus Lycii, Rhizoma Polygonati and Radix Rehmanniae are placed in extraction pot, add above-mentioned medical material 8~12 times of quality Purified water, reflux, extract, 1~3 times, each 1~2 hour, cross 120 mesh sieves, reclaim filtrate;
2) concentrating for the first time: by 1) filtrate that obtains is placed in efficient concentration tank, is evaporated to relative density when 60 DEG C It is 1.06~1.10, then 0~4 DEG C of cold preservation is placed 24 hours, obtains the filtrate after concentration;
3) centrifugal: the filtrate after concentrating is centrifugal in centrifuge, takes the supernatant;
4) second time concentrate: by the supernatant in efficient concentration tank, when concentrating under reduced pressure becomes 60 DEG C relative density be 1.2~ The viscous solution of 1.3;
5) pelletize:
1. above-mentioned viscous solution vacuum becoming the dry cream of moisture≤5wt%, pulverizes, cross 100 mesh sieves, get dry extract powder;
2. the method pressing equal increments, is added to maltodextrin in aspartame stirring while addingly, after 100 mesh sieves, Siftage is joined mix homogeneously in above-mentioned dried cream powder end, obtains mixture;
3. the mixture ethanol soft material of volume fraction 70%~95%, crosses 14 mesh sieves, obtains granule;
4. granule is less than 3wt% through 50 DEG C of forced air dryings to moisture;
The most again with 14 mesh sieve granulate;
6) subpackage: above-mentioned granule is weighed and is distributed into every part of 5g, sealing;
7) outer package: check qualified granule labeling, stores.
On the basis of technique scheme, the present invention can also do following improvement.
Further, 1) in, Radix Ginseng, Fructus Lycii, Rhizoma Polygonati and Radix Rehmanniae are placed in extraction pot, add above-mentioned medical material 10 times The purified water of quality, heated and boiled is extracted 3 times, each 1.5 hours, is crossed 120 mesh sieves, reclaim filtrate and merge.
Further, 2) and 4) in, the condition of described concentrating under reduced pressure is respectively-0.06~-0.08MP, and temperature is respectively 70 DEG C~80 DEG C.
Further, 3) in, described it is centrifuged as centrifugal under 14000r/min.
Further, 5) in, the ethanol of described soft material volume fraction 80% processed.
The invention has the beneficial effects as follows:
The preparation method of health food for relieving physical fatigue of the present invention use suitable extraction solid-liquid ratio, Extracting temperature, Extraction time and extraction time carry out micro-boiling and extract, and extraction ratio is high, and the crude extract amount obtained is conducive at concentration, centrifugation Reason, the required time cycle is short, and production efficiency is high, energy-conserving and environment-protective, energy consumption and low cost, and technical process is simple, is beneficial to be turned into continuously Industry, required material equipment is universal, is particularly adapted to batch production, can be used for the big production of industry, is with a wide range of applications.
Health food for relieving physical fatigue of the present invention is raw materials used has a following function:
Radix Ginseng is Araliaceae, Panax herbaceos perennial, is commonly called as people's rank, Coprinus atramentarius (Bull.) Fr. (Coprinus sterquilinus Fr.), Herba Stellariae Saxatilis, Radix Ginseng etc., and property is flat, micro- Temperature, sweet in the mouth, micro-hardship, to return spleen, lung meridian, heart channel, there is strongly invigorating primordial QI, multiple arteries and veins takes off admittedly, invigorating the spleen to benefit the lung, promoting the production of body fluid to quench thirst, Fructus Alpiniae Oxyphyllae of calming the nerves Effect.
Fructus Lycii is the dry mature fruit of plant of Solanaceae lycium barbarum Lycium barbarum L..It is mainly used in asthenia Damage of essence, soreness of waist and knee joint, vertigo and tinnitus, interior-heat quenches one's thirst, blood deficiency and yellow complexion, and blurred vision is not clear." property of medicine opinion " is mentioned: " can tonification essence Various symptoms and signs of deficiency, easy color, bleach, improving eyesight, calm the nerves.
Rhizoma Polygonati is the dry rhizome of liliaceous plant P. kingianum, Rhizoma Polygonati or Polygonatum cyrtonema Hua, and sweet in the mouth, property are flat, return spleen, lung, kidney Warp.Different by medical material shape, practise respectively and be referred to as " polygonatum sibiricum Redoute ", " RHIZOMA POLYGONATI ZINGIBERIFORME ", " big Rhizoma Polygonati "." Mingyi Bielu " is classified as Top grade, claim Rhizoma Polygonati tool the kidney invigorating and essence nourishing, nourshing Yin and drynsessmoistening prescription merit, for nourishing and fit keeping function and treatment deficiency of kidney essence, deficiency of the lung cough caused by dryness and spleen The longest history of disease that insufficiency of stomach is weak, is one of traditional Chinese medical science common drug.
Radix Rehmanniae is that scrophulariaceae rehmannia glutinosa plant Rehmanniag lutinosa Libosch. slowly bakees to about most probably dry Tuber.It is mainly used in warming febrile disease to join the army blood, fever of the body xerostomia, crimson tongue or the symptom such as red, has clearing away heat and promoting production of body fluid YIN nourishing, the merit nourished blood Effect.
Detailed description of the invention
Principle and feature to the present invention are described below, and example is served only for explaining the present invention, is not intended to limit Determine the scope of the present invention.
Embodiment 1
A kind of health food for relieving physical fatigue, is composed of the following raw materials by weight:
Radix Ginseng 201 parts, Fructus Lycii 201 parts, Rhizoma Polygonati 268 parts, maltodextrin 730 parts and aspartame 1 part.
1) extract: the various raw materials of proportional quantity are placed in extraction pot the purified water adding 10 times of quality, and heated and boiled carries Take 3 times, each 1.5 hours, cross 120 mesh sieves, reclaim filtrate and merge.
2) concentrate: take the filtrate after merging and subtract under the conditions of-0.06~-0.08MP, 70 DEG C~80 DEG C in efficient concentration tank When pressure is concentrated into 60 DEG C, relative density is that 1.06~1.10,0~4 DEG C of cold preservations are placed 24 hours, obtains the filtrate after concentration.
3) centrifugal: the filtrate after concentrating is in centrifuge, centrifugal under 14000r/min, takes the supernatant.
4) concentrate: the supernatant is reduced pressure dense in efficient concentration tank under the conditions of-0.06~-0.08MP, 70 DEG C~80 DEG C When shortening 60 DEG C into, relative density is the viscous solution of 1.2~1.3.
5) pelletize: 1. above-mentioned viscous solution is put in vacuum drying oven and makes dry cream (moisture≤5wt%), then with beating at a high speed Powder machine is pulverized, and crosses 100 mesh sieves, and get dry extract powder.2. the method pressing equal increments, joins maltodextrin stirring while addingly In aspartame, cross 100 mesh sieves, siftage is joined mix homogeneously in above-mentioned dried cream powder end, obtains mixture.3. mixture is used The ethanol soft material of volume fraction 80%, crosses 14 mesh sieves, obtains granule.4. granule is less than 3wt% through 50 DEG C of forced air dryings to moisture. The most again with 14 mesh sieve granulate.
6) subpackage: above-mentioned granule is weighed and is distributed into every part of 5g, sealing.
7) outer package: check qualified granule labeling, stores.
Through inspection, in granule prepared by the present embodiment, crude polysaccharides content is 385mg/100g.
Embodiment 2
A kind of health food for relieving physical fatigue, raw material is composed of the following raw materials by weight:
Radix Ginseng 201 parts, Fructus Lycii 201 parts, Radix Rehmanniae 268 parts, maltodextrin 720 parts and aspartame 1.1 parts.
1) extracting: the raw material of proportional quantity is placed in extraction pot the purified water adding 10 times of quality, heated and boiled extracts 3 Secondary, each 1.5 hours, cross 120 mesh sieves, reclaim filtrate, merging filtrate.
2) concentrate: take the filtrate after merging-0.06~-0.08MP, 70 DEG C~80 DEG C of concentrating under reduced pressure in efficient concentration tank It is that 1.06~1.10,0~4 DEG C of cold preservations are placed 24 hours to relative density when 60 DEG C, obtains the filtrate after concentration.
3) centrifugal: the filtrate after concentrating is in centrifuge, centrifugal under 14000r/min, takes the supernatant.
4) concentrate: by the supernatant in efficient concentration tank at-0.06~-0.08MP, 70 DEG C~80 DEG C concentrating under reduced pressure become When 60 DEG C, relative density is the viscous solution of 1.2~1.3.
5) pelletize: 1. above-mentioned viscous solution is put in vacuum drying oven the dry cream making moisture≤5wt%, then with beating at a high speed Powder machine is pulverized, and crosses 100 mesh sieves, and get dry extract powder.2. the method pressing equal increments, maltodextrin is added to stirring while addingly Ah In this Ba Tian, cross 100 mesh sieves, siftage is joined mix homogeneously in above-mentioned dried cream powder end, obtains mixture.3. volume fraction is used The ethanol soft material of 80%, crosses 14 mesh sieves, obtains granule.4. granule is less than 3wt% through 50 DEG C of forced air dryings to moisture.The most again with 14 Mesh sieve granulate.
6) subpackage: above-mentioned granule is weighed and is distributed into every part of 5g, sealing.
7) outer package: check qualified granule labeling, stores.
Through inspection, in granule prepared by the present embodiment, crude polysaccharides content is 344mg/100g.
Embodiment 3
A kind of health food for relieving physical fatigue, raw material is composed of the following components:
Radix Ginseng 201 parts, Rhizoma Polygonati 268 parts, Radix Rehmanniae 268 parts, maltodextrin 720 parts and aspartame 1.2 parts.
1) extracting: the various raw materials of proportional quantity are placed in extraction pot 10 times of quality purified water of addition, heated and boiled extracts 3 Secondary, each 1.5 hours, cross 120 mesh sieves, reclaim filtrate, merging filtrate.
2) concentrate: take the filtrate after merging-0.06~-0.08MP, 70 DEG C~80 DEG C of concentrating under reduced pressure in efficient concentration tank It is that 1.06~1.10,0~4 DEG C of cold preservations are placed 24 hours to relative density when 60 DEG C, obtains the filtrate after concentration.
3) centrifugal: the filtrate after concentrating is in centrifuge, centrifugal under 14000r/min, takes the supernatant.
4) concentrate: the supernatant-0.06~-0.08MP, 70 DEG C~80 DEG C of concentrating under reduced pressure in efficient concentration tank are become 60 DEG C time relative density be the viscous solution of 1.2~1.3.
5) pelletize: 1. above-mentioned viscous solution is put in vacuum drying oven the dry cream making moisture≤5wt%, then with beating at a high speed Powder machine is pulverized, and crosses 100 mesh sieves, and get dry extract powder.2. the method pressing equal increments, maltodextrin is added to stirring while addingly Ah In this Ba Tian, cross 100 mesh sieves, siftage is joined mix homogeneously in above-mentioned dried cream powder end, obtains mixture.3. mixture body The ethanol soft material of fraction 80%, crosses 14 mesh sieves, obtains granule.4. granule is less than 3wt% through 50 DEG C of forced air dryings to moisture.⑤ Again with 14 mesh sieve granulate.
6) subpackage: above-mentioned granule is weighed and is distributed into every part of 5g, sealing.
7) outer package: check qualified granule labeling, stores.
Through inspection, in granule prepared by the present embodiment, crude polysaccharides content is 312mg/100g.
Embodiment 4
A kind of health food for relieving physical fatigue, raw material is composed of the following components:
Radix Ginseng 201 parts, Fructus Lycii 201 parts, Rhizoma Polygonati 268 parts, Radix Rehmanniae 268 parts, maltodextrin 555 parts and aspartame 1.072 part.
1) extracting: the various raw materials of proportional quantity are placed in extraction pot 10 times of quality purified water of addition, heated and boiled extracts 3 Secondary, each 1.5 hours, cross 120 mesh sieves, reclaim filtrate, merging filtrate.
2) concentrate: take the filtrate after merging-0.06~-0.08MP, 70 DEG C~80 DEG C of concentrating under reduced pressure in efficient concentration tank It is that 1.06~1.10,0~4 DEG C of cold preservations are placed 24 hours to relative density when 60 DEG C, obtains the filtrate after concentration.
3) centrifugal: the filtrate after concentrating is in centrifuge, centrifugal under 14000r/min, takes the supernatant.
4) concentrate: the supernatant-0.06~-0.08MP, 70 DEG C~80 DEG C of concentrating under reduced pressure in efficient concentration tank are become 60 DEG C time relative density be the viscous solution of 1.2~1.3.
5) pelletize: 1. above-mentioned viscous solution is put in vacuum drying oven the dry cream making moisture≤5wt%, then with beating at a high speed Powder machine is pulverized, and crosses 100 mesh sieves, and get dry extract powder.2. the method pressing equal increments, maltodextrin is added to stirring while addingly Ah In this Ba Tian, cross 100 mesh sieves, siftage is joined mix homogeneously in above-mentioned dried cream powder end, obtains mixture.3. mixture body The ethanol soft material of fraction 80%, crosses 14 mesh sieves, obtains granule.4. granule is less than 3wt% through 50 DEG C of forced air dryings to moisture.⑤ Again with 14 mesh sieve granulate.
6) subpackage: above-mentioned granule is weighed and is distributed into every part of 5g, sealing.
7) outer package: check qualified granule labeling, stores.
Through inspection, granule prepared by the present embodiment slightly middle polyoses content is 430mg/100g.
Safety according to " health food inspection with assessment technique specification " (version in 2003) and functional trial are evaluated Program and method, the health food preparing the embodiment of the present invention 1 to embodiment 4 has carried out toxicology, and (prepared by embodiment 4 Health food be sample), function assessment (health food prepared by embodiment 1-4 is sample) evaluate.Experimental technique is as follows, real Test the results detailed in Table 1 to table 11.
1 acute toxicity test
1.1 laboratory animal SPF level KM mices, 20, male and female half and half, body weight 19~21g.
1.2 test method finished product tested material distilled water be configured to concentration be 0.5g/mL, maximum gavage capacity 30mL/Kg BW, gavage on the one give 20 mices (i.e. dosage is 30.0g/Kg BW, is equivalent to human body recommended amounts 120 times) for twice.Before gavage Water is can't help in animal fasting in 16 hours, and twice gavage is spaced 4 hours.Continuous Observation 14 days after gavage, and record animal poisoning symptom And death condition.On-test and at the end of weigh the weight of animals.
2 three genetic toxicity tests
2.1 Salmonella reversion test
2.1.1 experimental strain: Salmonella typhimurium histidine deficient TA97, TA98, TA100, TA102 tetra-strain
2.1.2 experimental technique and step: use the rat liver homogenate S9 of MOLTOX company of the U.S. as Activated in Vitro system. Be divided into 5 dosage, if negative control, certainly beam back change, Positive mutants agent comparison.
2.2 sperm malformation test
2.2.1 laboratory animal: SPF level KM mice, 25, male, body weight 25~35g.
2.2.2 experimental technique and step: be randomly divided into 5 groups by body weight, respectively negative control group, positive controls and High, medium and low three dosage groups, often group 5.
2.3 Micronucleus test
2.3.1 laboratory animal SPF level KM mice, 50, male and female half and half, body weight 25~30 parts.
2.3.2 5 groups it are randomly divided into, respectively negative control group, positive controls and high, medium and low three dosage groups, often groups Each 5 of male and female.
2.4 30 days feeding trials
2.4.1 laboratory animal SPF level SD rat 80, male and female half and half, 4 week old, body weight 60~80g.
2.4.2 test method is randomly divided into 4 groups by body weight, i.e. one negative control group and high, medium and low three dosage groups, Often each 10 of male and female of group.
Overall toxicological experiment result shows, this health food is more than 30.0g/Kg to the maximum tolerated dose of experimental animal BW (is equivalent to 120 times of human body recommended amounts), by acute toxicity grading criteria evaluation, belongs to nontoxic level.Salmonella reversion test, mouse bone marrow cells Polychromatic erythrocyte micronucleus test, mouse inbred strain result are feminine gender.Within 30 days, feeding trial result shows rat Have no obvious toxic-side effects.Result of the test is shown in Table 1 to table 8.
Table 1 sample acute toxicity test in mice result
Table 2 sample Salmonella reversion test result of the test for the first time
Table 3 positive thing comparison result of the test for the first time
Table 4 sample Salmonella reversion test second time result of the test
Table 5 positive thing comparison second time result of the test
Table 6 sample mouse inbred strain result
Note:Other deformities: include tail folding, double end, double tails etc.;*: compare with negative control group, P < 0.01.
The impact on Micronuclei In The Mouse Bone Marrow incidence rate of table 7 sample
Note: * *: compare with negative control group, P < 0.01;PCE: polychromatic erythrocyte, NCE: mature erythrocyte.
Table 8 sample on the impact of rat blood biochemical indicator (N=10)
Note: each dosage group compares with negative control group, P > 0.05.
2 function assessments test (function of physical fatigue alleviation)
Per os gavage gives the health food 30 days of mice embodiment 1 to embodiment 4 preparation, compares with matched group (distilled water) Relatively, each embodiment group can significantly improve the mice burden swimming time;Reduce the serum urea content after mice swimming;Improve mice Hepatic glycogen content;And embodiment 4 effect is best;Prompting, product of the present invention has function of relieving physical fatigue, embodiment 4 Effect is best, illustrates that Radix Rehmanniae and Radix Ginseng, Fructus Lycii, Rhizoma Polygonati compatibility have the effect of Synergistic.The results are shown in Table 9 to table 11.
The impact on the mice burden swimming time of table 9 sample
Note: each dosage group compares with negative control group, * P < 0.05, * * P < 0.01.
Table 10 sample is on the impact of serum urea content after mouse movement
Note: each dosage group compares with negative control group, * P < 0.05, * * P < 0.01.
The impact on Mouse Liver glycogen content of table 11 sample
Note: each dosage group compares with negative control group, * P < 0.05.
The foregoing is only presently preferred embodiments of the present invention, not in order to limit the present invention, all spirit in the present invention and Within principle, any modification, equivalent substitution and improvement etc. made, should be included within the scope of the present invention.

Claims (10)

1. a health food for relieving physical fatigue, it is characterised in that be composed of the following raw materials by weight:
Radix Ginseng 150~350 parts, Fructus Lycii 0~350 parts, Rhizoma Polygonati 0~300 parts, Radix Rehmanniae 0~300 parts, maltodextrin 500~ 700 parts and aspartame 0.5~1.5 parts.
Health food the most according to claim 1, it is characterised in that be composed of the following raw materials by weight:
Radix Ginseng 320~350 parts, Fructus Lycii 190~210 parts, Radix Rehmanniae 200~300 parts, maltodextrin 620~700 parts and A Si Ba Tian 0.5~1.5 parts.
Health food the most according to claim 1, it is characterised in that be composed of the following raw materials by weight:
Radix Ginseng 320~350 parts, Rhizoma Polygonati 190~210 parts, Radix Rehmanniae 200~300 parts, maltodextrin 620~700 parts and A Siba Sweet 0.5~1.5 part.
Health food the most according to claim 1, it is characterised in that be composed of the following raw materials by weight:
Radix Ginseng 200~250 parts, Fructus Lycii 200~250 parts, Rhizoma Polygonati 200~300 parts, Radix Rehmanniae 200~300 parts, maltodextrin 540~580 parts and aspartame 0.5~1.5 parts.
Health food the most according to claim 1, it is characterised in that be composed of the following raw materials by weight:
Radix Ginseng 201 parts, Fructus Lycii 201 parts, Rhizoma Polygonati 268 parts, Radix Rehmanniae 268 parts, maltodextrin 555 parts and aspartame 1.072 Part.
6. the preparation method of the health food as described in claim 1-5 is arbitrary, it is characterised in that including:
1) extract: Radix Ginseng, Fructus Lycii, Rhizoma Polygonati and Radix Rehmanniae are placed in extraction pot, add the pure of above-mentioned medical material 8~12 times of quality Change water, reflux, extract, 1~3 times, each 1~2 hour, cross 120 mesh sieves, reclaim filtrate;
2) concentrating for the first time: by 1) filtrate that obtains is placed in efficient concentration tank, and being evaporated to relative density when 60 DEG C is 1.06~1.10, then 0~4 DEG C of cold preservation places 24 hours, obtains the filtrate after concentration;
3) centrifugal: the filtrate after concentrating is centrifugal in centrifuge, takes the supernatant;
4) second time concentrates: by the supernatant in efficient concentration tank, when concentrating under reduced pressure becomes 60 DEG C, relative density is 1.2~1.3 Viscous solution;
5) pelletize:
1. above-mentioned viscous solution vacuum becoming the dry cream of moisture≤5wt%, pulverizes, cross 100 mesh sieves, get dry extract powder;
2. the method pressing equal increments, is added to maltodextrin in aspartame stirring while addingly, after 100 mesh sieves, and will sieve Lower thing joins mix homogeneously in above-mentioned dried cream powder end, obtains mixture;
3. the mixture ethanol soft material of volume fraction 70%~95%, crosses 14 mesh sieves, obtains granule;
4. granule is less than 3wt% through 50 DEG C of forced air dryings to moisture;
The most again with 14 mesh sieve granulate;
6) subpackage: above-mentioned granule is weighed and is distributed into every part of 5g, sealing;
7) outer package: check qualified granule labeling, stores.
Preparation method the most according to claim 6, it is characterised in that 1) in, by Radix Ginseng, Fructus Lycii, Rhizoma Polygonati and the Radix Rehmanniae Huang is placed in extraction pot, adds the purified water of above-mentioned 10 times of quality of medical material, and heated and boiled is extracted 3 times, each 1.5 hours, crosses 120 Mesh sieve, reclaims filtrate and merges.
Preparation method the most according to claim 6, it is characterised in that 2) and 4) in, the condition of described concentrating under reduced pressure is divided Not Wei-0.06~-0.08MP, temperature is respectively 70 DEG C~80 DEG C.
Preparation method the most according to claim 6, it is characterised in that 3) in, described be centrifuged under 14000r/min from The heart.
Preparation method the most according to claim 6, it is characterised in that 5) in, described soft material volume fraction 80% processed Ethanol.
CN201610517366.5A 2016-07-04 2016-07-04 Healthcare food capable of relieving physical fatigue and making method thereof Pending CN106036879A (en)

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CN107114761A (en) * 2017-06-13 2017-09-01 通化康元生物科技有限公司 Inonotus obliquus ginseng sealwort piece
CN108354176A (en) * 2017-12-19 2018-08-03 康美(北京)药物研究院有限公司 Health food and preparation method thereof containing pueraria lobata
CN108420075A (en) * 2018-05-09 2018-08-21 江苏自然之道生物科技有限公司 A kind of product for alleviating physical fatigue
CN112841654A (en) * 2021-01-29 2021-05-28 石家庄以岭药业股份有限公司 Anti-fatigue composition and anti-fatigue health food containing same

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CN103099833A (en) * 2011-11-14 2013-05-15 甘肃创兴生物工程有限责任公司 Soft capsule helpful for relieving sports fatigue and delaying aging and preparation method thereof
CN104082822A (en) * 2014-07-22 2014-10-08 湖南湘泉药业股份有限公司 Rhizome polygonati, medlar and ginseng solid beverage and preparation method thereof

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CN1142924A (en) * 1995-05-11 1997-02-19 毕长宏 Health drink
CN101322774A (en) * 2008-03-25 2008-12-17 深圳力瑞医药科技有限公司 Medicament composition with fatigue-resisting function and preparation method and application thereof
CN101747446A (en) * 2008-12-04 2010-06-23 东北师范大学 Method for extracting anti-fatigue acidic ginseng polysaccharide
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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107114761A (en) * 2017-06-13 2017-09-01 通化康元生物科技有限公司 Inonotus obliquus ginseng sealwort piece
CN108354176A (en) * 2017-12-19 2018-08-03 康美(北京)药物研究院有限公司 Health food and preparation method thereof containing pueraria lobata
CN108420075A (en) * 2018-05-09 2018-08-21 江苏自然之道生物科技有限公司 A kind of product for alleviating physical fatigue
CN112841654A (en) * 2021-01-29 2021-05-28 石家庄以岭药业股份有限公司 Anti-fatigue composition and anti-fatigue health food containing same

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Application publication date: 20161026