CN105992517B - 异噁唑啉化合物的抗寄生虫用途 - Google Patents
异噁唑啉化合物的抗寄生虫用途 Download PDFInfo
- Publication number
- CN105992517B CN105992517B CN201480067168.2A CN201480067168A CN105992517B CN 105992517 B CN105992517 B CN 105992517B CN 201480067168 A CN201480067168 A CN 201480067168A CN 105992517 B CN105992517 B CN 105992517B
- Authority
- CN
- China
- Prior art keywords
- fleas
- flea
- isoxazoline
- fluralaner
- isoxazoline compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/80—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Environmental Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13196539 | 2013-12-10 | ||
| EP13196539.4 | 2013-12-10 | ||
| PCT/EP2014/076959 WO2015086551A1 (en) | 2013-12-10 | 2014-12-09 | Antiparasitic use of isoxazoline compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105992517A CN105992517A (zh) | 2016-10-05 |
| CN105992517B true CN105992517B (zh) | 2020-03-06 |
Family
ID=49759099
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201480067168.2A Active CN105992517B (zh) | 2013-12-10 | 2014-12-09 | 异噁唑啉化合物的抗寄生虫用途 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US9655884B2 (https=) |
| EP (1) | EP3079474B1 (https=) |
| JP (1) | JP6530753B2 (https=) |
| CN (1) | CN105992517B (https=) |
| AU (1) | AU2014363695B2 (https=) |
| BR (1) | BR112016013020B1 (https=) |
| CA (1) | CA2932790C (https=) |
| DK (1) | DK3079474T3 (https=) |
| ES (1) | ES2742815T3 (https=) |
| HU (1) | HUE046067T2 (https=) |
| PL (1) | PL3079474T3 (https=) |
| PT (1) | PT3079474T (https=) |
| RU (1) | RU2673723C1 (https=) |
| WO (1) | WO2015086551A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112017027855B1 (pt) * | 2015-06-23 | 2022-11-16 | Intervet International B.V. | Composição farmacêutica, seu uso, água potável medicamentosa e método para sua preparação |
| CN107535510A (zh) * | 2017-09-29 | 2018-01-05 | 北京科发伟业农药技术中心 | 一种含fluralaner的组合物 |
| US11648238B2 (en) | 2017-12-12 | 2023-05-16 | Intervet Inc. | Implantable isoxazoline pharmaceutical compositions and uses thereof |
| BR112022000982A2 (pt) | 2019-07-22 | 2022-03-08 | Intervet Int Bv | Forma de dosagem veterinária mastigável macia |
| EP4075981A1 (en) * | 2019-12-16 | 2022-10-26 | Intervet International B.V. | Composition for lice control |
| EP4077286A1 (en) | 2019-12-18 | 2022-10-26 | Elanco Tiergesundheit AG | Isoxazoline derivatives as pesticides |
| KR20230043904A (ko) | 2020-07-24 | 2023-03-31 | 엘랑코 유에스 인코포레이티드 | 이속사졸린 화합물 및 이의 중간체의 제조 공정 |
| CN116744917A (zh) | 2020-09-04 | 2023-09-12 | 礼蓝美国公司 | 适口调配物 |
| WO2022192623A1 (en) * | 2021-03-11 | 2022-09-15 | In The Bowl Animal Health, Inc. | Oral canine feed and methods for controlling flea infestations in a canine |
| CN117769356A (zh) * | 2021-06-25 | 2024-03-26 | 碗中动物健康公司 | 猫科动物口服饲料和在猫科动物中控制蜱侵袭的方法 |
| DK182016B1 (en) | 2023-03-13 | 2025-05-28 | Zoetis Services Llc | Degradation of isoxazolines in ozonated sea water |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1323161A (zh) * | 1998-10-09 | 2001-11-21 | 诺瓦提斯公司 | 防治跳蚤的虱螨脲和烯淀虫胺口服组合物 |
| CN101778566A (zh) * | 2007-08-17 | 2010-07-14 | 英特威国际有限公司 | 异噁唑啉组合物及其作为抗寄生虫药的用途 |
| WO2013150055A1 (en) * | 2012-04-04 | 2013-10-10 | Intervet International B.V. | Solid oral pharmaceutical compositions for isoxazoline compounds |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1984001100A1 (en) | 1982-09-17 | 1984-03-29 | Edward Ireland | Improved dental matrix band |
| CN1103544C (zh) * | 1996-08-02 | 2003-03-26 | 诺瓦提斯公司 | 陆栖哺乳动物用2,4－二烯酸型杀虫剂系统性给药的改进方法 |
| US20070043011A1 (en) | 2003-09-30 | 2007-02-22 | Eitatsu Ikeda | Substituted benzanilide compound and noxious organism controlling agent |
| CN101768129B (zh) | 2004-03-05 | 2012-05-23 | 日产化学工业株式会社 | 异*唑啉取代苯甲酰胺化合物的制备中间体 |
| TWI412322B (zh) | 2005-12-30 | 2013-10-21 | Du Pont | 控制無脊椎害蟲之異唑啉 |
| WO2008108448A1 (ja) | 2007-03-07 | 2008-09-12 | Nissan Chemical Industries, Ltd. | イソキサゾリン置換ベンズアミド化合物及び有害生物防除剤 |
| DE102007028871A1 (de) | 2007-06-22 | 2008-12-24 | Clariant International Limited | Verfahren zur Herstellung von reinem C.I. Pigment Orange 74 |
| TWI430995B (zh) | 2007-06-26 | 2014-03-21 | Du Pont | 萘異唑啉無脊椎有害動物控制劑 |
| KR101769728B1 (ko) | 2007-06-27 | 2017-08-18 | 이 아이 듀폰 디 네모아 앤드 캄파니 | 동물 해충 방제 방법 |
| TWI411395B (zh) | 2007-12-24 | 2013-10-11 | Syngenta Participations Ag | 殺蟲化合物 |
| US8377942B2 (en) | 2008-12-18 | 2013-02-19 | Novartis Ag | Isoxazolines derivatives and their use as pesticide |
| HUE015568T4 (en) | 2008-12-19 | 2017-10-30 | Elanco Tiergesundheit Ag | Isoxazoline derivatives and their use as pesticides |
| EP3216448B8 (en) | 2012-02-06 | 2019-06-05 | Boehringer Ingelheim Animal Health USA Inc. | Parasiticidal oral veterinary compositions comprising systemically-acting active agents, methods and uses thereof |
-
2014
- 2014-12-09 US US15/101,430 patent/US9655884B2/en active Active
- 2014-12-09 ES ES14809838T patent/ES2742815T3/es active Active
- 2014-12-09 PL PL14809838T patent/PL3079474T3/pl unknown
- 2014-12-09 CN CN201480067168.2A patent/CN105992517B/zh active Active
- 2014-12-09 PT PT14809838T patent/PT3079474T/pt unknown
- 2014-12-09 HU HUE14809838A patent/HUE046067T2/hu unknown
- 2014-12-09 JP JP2016537438A patent/JP6530753B2/ja active Active
- 2014-12-09 CA CA2932790A patent/CA2932790C/en active Active
- 2014-12-09 DK DK14809838.7T patent/DK3079474T3/da active
- 2014-12-09 BR BR112016013020-0A patent/BR112016013020B1/pt active IP Right Grant
- 2014-12-09 EP EP14809838.7A patent/EP3079474B1/en not_active Revoked
- 2014-12-09 RU RU2016127304A patent/RU2673723C1/ru active
- 2014-12-09 AU AU2014363695A patent/AU2014363695B2/en active Active
- 2014-12-09 WO PCT/EP2014/076959 patent/WO2015086551A1/en not_active Ceased
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1323161A (zh) * | 1998-10-09 | 2001-11-21 | 诺瓦提斯公司 | 防治跳蚤的虱螨脲和烯淀虫胺口服组合物 |
| CN101778566A (zh) * | 2007-08-17 | 2010-07-14 | 英特威国际有限公司 | 异噁唑啉组合物及其作为抗寄生虫药的用途 |
| WO2013150055A1 (en) * | 2012-04-04 | 2013-10-10 | Intervet International B.V. | Solid oral pharmaceutical compositions for isoxazoline compounds |
Also Published As
| Publication number | Publication date |
|---|---|
| BR112016013020B1 (pt) | 2020-12-01 |
| WO2015086551A1 (en) | 2015-06-18 |
| DK3079474T3 (da) | 2019-09-16 |
| JP2016539960A (ja) | 2016-12-22 |
| EP3079474B1 (en) | 2019-07-03 |
| CA2932790A1 (en) | 2015-06-18 |
| RU2673723C1 (ru) | 2018-11-29 |
| ES2742815T3 (es) | 2020-02-17 |
| JP6530753B2 (ja) | 2019-06-12 |
| AU2014363695A1 (en) | 2016-06-09 |
| HUE046067T2 (hu) | 2020-02-28 |
| US20160303086A1 (en) | 2016-10-20 |
| CN105992517A (zh) | 2016-10-05 |
| US9655884B2 (en) | 2017-05-23 |
| AU2014363695B2 (en) | 2018-12-13 |
| PT3079474T (pt) | 2019-09-10 |
| EP3079474A1 (en) | 2016-10-19 |
| BR112016013020A2 (pt) | 2017-08-08 |
| PL3079474T3 (pl) | 2019-10-31 |
| CA2932790C (en) | 2021-10-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |