RU2673723C1 - Применение содержащих изоксазолин соединений в качестве противопаразитарных средств - Google Patents

Применение содержащих изоксазолин соединений в качестве противопаразитарных средств Download PDF

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Publication number
RU2673723C1
RU2673723C1 RU2016127304A RU2016127304A RU2673723C1 RU 2673723 C1 RU2673723 C1 RU 2673723C1 RU 2016127304 A RU2016127304 A RU 2016127304A RU 2016127304 A RU2016127304 A RU 2016127304A RU 2673723 C1 RU2673723 C1 RU 2673723C1
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RU
Russia
Prior art keywords
isoxazoline
fleas
trifluoromethyl
methyl
fluralaner
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RU2016127304A
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English (en)
Russian (ru)
Inventor
Хайке ВИЛЛЬЯМС
Хартмут ЦОЛЛЕР
Аня Регина ХЕККЕРОТ
Original Assignee
Интервет Интернэшнл Б.В.
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Application filed by Интервет Интернэшнл Б.В. filed Critical Интервет Интернэшнл Б.В.
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/80Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/14Ectoparasiticides, e.g. scabicides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D261/00Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/08Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
RU2016127304A 2013-12-10 2014-12-09 Применение содержащих изоксазолин соединений в качестве противопаразитарных средств RU2673723C1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13196539 2013-12-10
EP13196539.4 2013-12-10
PCT/EP2014/076959 WO2015086551A1 (en) 2013-12-10 2014-12-09 Antiparasitic use of isoxazoline compounds

Publications (1)

Publication Number Publication Date
RU2673723C1 true RU2673723C1 (ru) 2018-11-29

Family

ID=49759099

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2016127304A RU2673723C1 (ru) 2013-12-10 2014-12-09 Применение содержащих изоксазолин соединений в качестве противопаразитарных средств

Country Status (14)

Country Link
US (1) US9655884B2 (https=)
EP (1) EP3079474B1 (https=)
JP (1) JP6530753B2 (https=)
CN (1) CN105992517B (https=)
AU (1) AU2014363695B2 (https=)
BR (1) BR112016013020B1 (https=)
CA (1) CA2932790C (https=)
DK (1) DK3079474T3 (https=)
ES (1) ES2742815T3 (https=)
HU (1) HUE046067T2 (https=)
PL (1) PL3079474T3 (https=)
PT (1) PT3079474T (https=)
RU (1) RU2673723C1 (https=)
WO (1) WO2015086551A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2823297C1 (ru) * 2023-11-20 2024-07-22 Общество с ограниченной ответственностью "ВЕТФАРМСТАНДАРТ" Ветеринарный фармацевтический продукт против эктопаразитов собак

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112017027855B1 (pt) * 2015-06-23 2022-11-16 Intervet International B.V. Composição farmacêutica, seu uso, água potável medicamentosa e método para sua preparação
CN107535510A (zh) * 2017-09-29 2018-01-05 北京科发伟业农药技术中心 一种含fluralaner的组合物
US11648238B2 (en) 2017-12-12 2023-05-16 Intervet Inc. Implantable isoxazoline pharmaceutical compositions and uses thereof
BR112022000982A2 (pt) 2019-07-22 2022-03-08 Intervet Int Bv Forma de dosagem veterinária mastigável macia
EP4075981A1 (en) * 2019-12-16 2022-10-26 Intervet International B.V. Composition for lice control
EP4077286A1 (en) 2019-12-18 2022-10-26 Elanco Tiergesundheit AG Isoxazoline derivatives as pesticides
KR20230043904A (ko) 2020-07-24 2023-03-31 엘랑코 유에스 인코포레이티드 이속사졸린 화합물 및 이의 중간체의 제조 공정
CN116744917A (zh) 2020-09-04 2023-09-12 礼蓝美国公司 适口调配物
WO2022192623A1 (en) * 2021-03-11 2022-09-15 In The Bowl Animal Health, Inc. Oral canine feed and methods for controlling flea infestations in a canine
CN117769356A (zh) * 2021-06-25 2024-03-26 碗中动物健康公司 猫科动物口服饲料和在猫科动物中控制蜱侵袭的方法
DK182016B1 (en) 2023-03-13 2025-05-28 Zoetis Services Llc Degradation of isoxazolines in ozonated sea water

Citations (4)

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EP1119256B1 (en) * 1998-10-09 2003-06-04 Novartis AG Oral combination of lufenuron and nitenpyram against fleas
WO2009024541A2 (en) * 2007-08-17 2009-02-26 Intervet International B.V. Isoxazoline compositions and their use as antiparasitics
RU2473541C9 (ru) * 2007-04-23 2013-06-20 Байер Кропсайенс Аг Инсектицидные арилпирролидины
WO2013150055A1 (en) * 2012-04-04 2013-10-10 Intervet International B.V. Solid oral pharmaceutical compositions for isoxazoline compounds

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TWI412322B (zh) 2005-12-30 2013-10-21 Du Pont 控制無脊椎害蟲之異唑啉
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TWI411395B (zh) 2007-12-24 2013-10-11 Syngenta Participations Ag 殺蟲化合物
US8377942B2 (en) 2008-12-18 2013-02-19 Novartis Ag Isoxazolines derivatives and their use as pesticide
HUE015568T4 (en) 2008-12-19 2017-10-30 Elanco Tiergesundheit Ag Isoxazoline derivatives and their use as pesticides
EP3216448B8 (en) 2012-02-06 2019-06-05 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal oral veterinary compositions comprising systemically-acting active agents, methods and uses thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1119256B1 (en) * 1998-10-09 2003-06-04 Novartis AG Oral combination of lufenuron and nitenpyram against fleas
RU2473541C9 (ru) * 2007-04-23 2013-06-20 Байер Кропсайенс Аг Инсектицидные арилпирролидины
WO2009024541A2 (en) * 2007-08-17 2009-02-26 Intervet International B.V. Isoxazoline compositions and their use as antiparasitics
WO2013150055A1 (en) * 2012-04-04 2013-10-10 Intervet International B.V. Solid oral pharmaceutical compositions for isoxazoline compounds

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2823297C1 (ru) * 2023-11-20 2024-07-22 Общество с ограниченной ответственностью "ВЕТФАРМСТАНДАРТ" Ветеринарный фармацевтический продукт против эктопаразитов собак
RU2847348C1 (ru) * 2024-04-27 2025-10-03 Общество С Ограниченной Ответственностью "Научно-Исследовательский Центр "Фарматол" Противопаразитарное средство для лечения и профилактики эктопаразитозов собак.
RU2847346C1 (ru) * 2024-05-13 2025-10-03 Общество С Ограниченной Ответственностью "Научно-Исследовательский Центр "Фарматол" Противопаразитарное средство для лечения и профилактики эктопаразитозов собак и кошек

Also Published As

Publication number Publication date
BR112016013020B1 (pt) 2020-12-01
WO2015086551A1 (en) 2015-06-18
DK3079474T3 (da) 2019-09-16
JP2016539960A (ja) 2016-12-22
EP3079474B1 (en) 2019-07-03
CA2932790A1 (en) 2015-06-18
ES2742815T3 (es) 2020-02-17
JP6530753B2 (ja) 2019-06-12
AU2014363695A1 (en) 2016-06-09
HUE046067T2 (hu) 2020-02-28
US20160303086A1 (en) 2016-10-20
CN105992517B (zh) 2020-03-06
CN105992517A (zh) 2016-10-05
US9655884B2 (en) 2017-05-23
AU2014363695B2 (en) 2018-12-13
PT3079474T (pt) 2019-09-10
EP3079474A1 (en) 2016-10-19
BR112016013020A2 (pt) 2017-08-08
PL3079474T3 (pl) 2019-10-31
CA2932790C (en) 2021-10-12

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