CN105963710A - 具有延长的体内功效的生长激素 - Google Patents

具有延长的体内功效的生长激素 Download PDF

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Publication number
CN105963710A
CN105963710A CN201610416630.6A CN201610416630A CN105963710A CN 105963710 A CN105963710 A CN 105963710A CN 201610416630 A CN201610416630 A CN 201610416630A CN 105963710 A CN105963710 A CN 105963710A
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China
Prior art keywords
conjugate
nhc
growth hormone
independently selected
syndrome
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CN201610416630.6A
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English (en)
Chinese (zh)
Inventor
N.L.约翰森
H.S.安德森
J.布夏特
C.贝伦斯
L.诺斯科夫-劳里特森
J.苏
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Novo Nordisk AS
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Novo Nordisk AS
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Publication of CN105963710A publication Critical patent/CN105963710A/zh
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    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
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    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/27Growth hormone [GH], i.e. somatotropin
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  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
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  • Chemical & Material Sciences (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
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  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Neurosurgery (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Psychiatry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pain & Pain Management (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Dermatology (AREA)
  • Toxicology (AREA)
CN201610416630.6A 2009-08-06 2010-08-06 具有延长的体内功效的生长激素 Pending CN105963710A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP09167350.9 2009-08-06
EP09167350 2009-08-06
US23296709P 2009-08-11 2009-08-11
US61/232967 2009-08-11
CN2010800357644A CN102612376A (zh) 2009-08-06 2010-08-06 具有延长的体内功效的生长激素

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CN105963710A true CN105963710A (zh) 2016-09-28

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CN2010800357644A Pending CN102612376A (zh) 2009-08-06 2010-08-06 具有延长的体内功效的生长激素

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US (4) US8841249B2 (cg-RX-API-DMAC7.html)
EP (1) EP2461831B1 (cg-RX-API-DMAC7.html)
JP (2) JP6086528B2 (cg-RX-API-DMAC7.html)
CN (2) CN105963710A (cg-RX-API-DMAC7.html)
WO (1) WO2011015649A1 (cg-RX-API-DMAC7.html)

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