CN105963527A - Traditional Chinese medicine extracting solution capable of quickly healing wound and preparation method thereof - Google Patents
Traditional Chinese medicine extracting solution capable of quickly healing wound and preparation method thereof Download PDFInfo
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Abstract
The invention relates to quick wound healing medicine, in particular to a traditional Chinese medicine extracting solution capable of quickly healing a wound and a preparation method thereof. The traditional Chinese medicine extracting solution is prepared from radix angelica sinensis, radix sanguisorbae, radix lithospermi, radix et rhizoma rhei, coptidis rhizomes, cortex phellodendri, rhizoma polygoni cuspidate, frankincense, diverse wormwood herb, rhizoma bletillae, radix angelicae dahuricae, myrrh, cortex meliae, borneol and dragon's blood. Compared with the prior art, the traditional Chinese medicine extracting solution has the advantages that all the Chinese herbs cooperate with one another through scientific compatibility to achieve the highest herbal efficacy; meanwhile, the ingredients of the Chinese herbs are effectively extracted through the unique preparation method to fully achieve the herbal efficacy of the Chinese herbs; in addition, little toxicity and few side effects of the Chinese herbs can be effectively removed by adopting the extracting solution mode, and then the purpose of quickly healing the wound is achieved.
Description
Technical field
The present invention relates to wound healing medicine, particularly relate to a kind of wound healing Chinese medicine extraction liquid and preparation method thereof.
Background technology
In the daily life of the mankind, the mankind are often as be not intended to or other situations cause phenomenon that wound occur, therefore, from ancient times to the present, skin trauma, damage are all surgical clinical commonly encountered diseases, and such as burn and scald, various wound, skin ulcer, mucosa injury etc. broadly fall into surgical wound, as cured not in time, pathogenic factor and antibacterial invade, not only can expand wound surface, skin ulceration, even cause infection, produce septicemia, cause death.Repair in trauma is one of study hotspot in surgical field all the time.Wound healing is the pathological process caused after wound, is jointly to be participated in by multiple somatomedin, cytokine, inflammatory cell and repair cell, the complicated and process of hight coordinate.Wound is complicated, and influence factor is numerous, except fibroblast, inflammatory cell, somatomedin, Fn Fiberonectin trace element, pH value etc., also extracellular matrix, epidermis cell and cytokine profiles.
Modern medicine is thought, the agglutination of wound surface is generally divided into local inflammation reaction, cell proliferation and differentiation and Reconstruction 3 the most different stage overlapping again.These 3 any one links of stage are affected, and all may cause the prolongation of wound healing time, therefore, effectively control local infection, promote cell proliferation, increase collage synthesis and wound surface nutrition, become the acceleration effective method of wound healing.
Specifically, skin wound healing is the repair process after skin histology sustains damage, and repair process includes that inflammatory reaction, hyperplasia and cambium are reinvented.Inflammatory reaction includes various cytokine, leukocyte etc.；Cell neogenesis includes the autologous propagation of fibroblast or mesenchymal cell is divided into fibroblast etc.；Tissue remodeling includes the skin histology being rearranged into certain function in order of fibroblast.Thus, fibroblast is the host cell composition in dermis of skin, and it has together constituted with the main body of corium with collagen fiber, elastic fiber and the matrix components self secreted.The major function of fibroblast is: synthesize and secrete collagen fiber, elastic fiber, Matrix protein material and some somatomedin, the elasticity and toughness maintaining skin is had important function, and the minimizing of fibroblast is also the major reason causing wrinkle to produce.
But Shortcomings in conventional wound medicine.Such as disinfectant (povidone iodine etc.), the use of adhesive bandage, sterilizing effect can be played, but trauma pain can not be reduced；External lidocaine emulsifiable paste and aerosol, can play analgesic effect, but it is poor to control infection；Other is with Chinese medicine extract as principal agent, is mostly medical mechanical domain, and quality control standard is the strictest；It mostly is ointment, liniment in topical drug dosage form, is administered and there is inconvenience.
Summary of the invention
The present invention is directed to the deficiency of pure existence in above-mentioned traditional wound medicine, propose wound healing Chinese medicine extraction liquid that a kind of formula is reasonable, simple for production, wound healing fast, healed and preparation method thereof.
In order to achieve the above object, the technical solution used in the present invention is, the present invention provides a kind of wound healing Chinese medicine extraction liquid, it is characterized in that, including following active princlple: Radix Angelicae Sinensis, Radix Sanguisorbae, Radix Arnebiae (Radix Lithospermi), Radix Et Rhizoma Rhei, Rhizoma Coptidis, Cortex Phellodendri, Rhizoma Polygoni Cuspidati, Olibanum, Herba Artemisiae Anomalae, Pseudobulbus Bletillae (Rhizoma Bletillae), the Radix Angelicae Dahuricae, Myrrha, Cortex Meliae, Borneolum Syntheticum, Sanguis Draxonis.
As preferably, include following active princlple according to parts by weight: Radix Angelicae Sinensis 5 parts～10 parts, Radix Sanguisorbae 10 parts～20 parts, Radix Arnebiae (Radix Lithospermi) 5 parts～10 parts, Radix Et Rhizoma Rhei 5 parts～10 parts, Rhizoma Coptidis 7 parts～15 parts, Cortex Phellodendri 5 parts～10 parts, Rhizoma Polygoni Cuspidati 3 parts～8 parts, Olibanum 5 parts～10 parts, Herba Artemisiae Anomalae 5 parts～10 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 5 parts～10 parts, the Radix Angelicae Dahuricae 5 parts～10 parts, Myrrha 7 parts～15 parts, Cortex Meliae 5 parts～10 parts, Borneolum Syntheticum 2 parts～8 parts, Sanguis Draxonis 5 parts～10 parts.
It is further preferred that include following active princlple according to parts by weight: Radix Angelicae Sinensis 10 parts, Radix Sanguisorbae 20 parts, Radix Arnebiae (Radix Lithospermi) 10 parts, Radix Et Rhizoma Rhei 10 parts, Rhizoma Coptidis 8 parts, Cortex Phellodendri 10 parts, Rhizoma Polygoni Cuspidati 5 parts, Olibanum 8 parts, Herba Artemisiae Anomalae 10 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 7 parts, the Radix Angelicae Dahuricae 8 parts, Myrrha 7 parts, Cortex Meliae 5 parts, Borneolum Syntheticum 6 parts, Sanguis Draxonis 10 parts.
Present invention also offers the method preparing above-mentioned wound healing Chinese medicine extraction liquid, comprise the following steps:
A, by ready Chinese medicine component in boiling water rapid soaking filter under, pull out the most rapidly, drain；
B, will drain after Chinese medicine cutting become unqualified shape, in being then placed in pot, dry pot stir-fries；
C, will stir-fry after Chinese medicine put in pot, add water, slow fire boils 1 hour；
D, after liquid medicine cooling in pot, Chinese medicine and liquid medicine are put into fermentation tank, add strain, ferment；
E, after fermentation completes, take out the Chinese medicine that ferments and liquid medicine, filter, obtain filtrate；
F, carrying out high temperature compressed by filtrate, being compressed to relative concentration is 1.5～1.7, i.e. obtains finished product.
As preferably, in described step c, amount of water is 2～3 times of Chinese medicine gross weight.
As preferably, in described Step d, strain is the mixture of yeast and bacillus bifidus, amount is Chinese medicine gross weight 1%～the 4% of described interpolation strain.
As preferably, the mass ratio of described yeast and bacillus bifidus is 1:1.5.
As preferably, described bacillus bifidus is at least one probiotics in bifidobacterium longum, bifidobacterium breve, avette bacillus bifidus, bifidobacterium thermophilum.
As preferably, in described Step d, controlling fermentation temperature 24 DEG C～28 DEG C in fermentation tank, fermentation time is 28～48 hours.
Compared with prior art, advantages of the present invention and good effect are,
1, the present invention is by providing a kind of Chinese medicine extraction liquid, utilize the compatibility of science, make between each Chinese medicine the most collaborative, play maximum drug effect, simultaneously, utilize unique preparation method, effectively the composition of Chinese medicine is extracted, give full play to the drug effect of Chinese medicine, and, use the mode of extracting solution, it is also possible to the effective removal micro-toxicity of Chinese medicine and little side effect, and then reach the purpose of rapid healing wound.
Detailed description of the invention
In order to be more clearly understood that the above-mentioned purpose of the present invention, feature and advantage, below in conjunction with embodiment, the present invention will be further described.It should be noted that in the case of not conflicting, the feature in embodiments herein and embodiment can be mutually combined.
Elaborate a lot of detail in the following description so that fully understanding the present invention, but, the present invention can be different from other modes described here with employing and implement, and therefore, the present invention is not limited to the restriction of the specific embodiment of description described below.
Embodiment 1, the present embodiment provides a kind of wound healing Chinese medicine extraction liquid, including following active princlple: Radix Angelicae Sinensis 5 parts, Radix Sanguisorbae 10 parts, Radix Arnebiae (Radix Lithospermi) 5 parts, Radix Et Rhizoma Rhei 5 parts, Rhizoma Coptidis 7 parts, Cortex Phellodendri 5 parts, Rhizoma Polygoni Cuspidati 3 parts, Olibanum 5 parts, Herba Artemisiae Anomalae 5 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 5 parts, the Radix Angelicae Dahuricae 5 parts, Myrrha 7 parts, Cortex Meliae 5 parts, Borneolum Syntheticum 2 parts, Sanguis Draxonis 5 parts.
In above-mentioned formula, Radix Angelicae Sinensis has enriches blood；Invigorate blood circulation；Menstruction regulating and pain relieving；Moisturize effect of laxation, it is possible to enrich blood, invigorate blood circulation, and there is antibacterial, arteriosclerosis effect；Radix Sanguisorbae has cooling blood for hemostasis, heat-clearing and toxic substances removing, effect of detumescence sore；Radix Arnebiae (Radix Lithospermi), has removing heat from blood, invigorates blood circulation, effect of removing toxic substances rash；Radix Et Rhizoma Rhei has effect of blood circulation promoting and blood stasis dispelling；Rhizoma Coptidis has a heat clearing and damp drying, eliminating fire and detoxication, more can and Radix Et Rhizoma Rhei between more preferable compatibility, improve effect；Cortex Phellodendri, has effect of heat-clearing and toxic substances removing, heat clearing and damp drying；Rhizoma Polygoni Cuspidati has effect of heat-clearing and toxic substances removing, and has treatment burn due to hot liquid or fire, injury from falling down, the effect of carbuncle sore tumefacting virus；Olibanum has more significant analgesic activity, and can have more intensive bacteriostasis；Herba Artemisiae Anomalae has the effect of hemostasis of curing the wound；Pseudobulbus Bletillae (Rhizoma Bletillae) has astringing to arrest bleeding, effect of detumescence and promoting granulation；The Radix Angelicae Dahuricae has evacuation of pus of invigorating blood circulation, effect of granulation promoting pain relieving；Myrrha has the effect such as promoting blood circulation and stopping pain, detumescence and promoting granulation；Cortex Meliae has effect of heat clearing away；Borneolum Syntheticum has effect of reducing swelling and alleviating pain；Sanguis Draxonis has blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, astringing to arrest bleeding, the remarkable efficacy such as hard masses softening and resolving, promoting tissue regeneration and ulcer healing, by above-mentioned Chinese medicinal ingredients, with Sanguis Draxonis, Herba Artemisiae Anomalae, Radix Sanguisorbae, Radix Et Rhizoma Rhei as monarch drug, it is equipped with Radix Arnebiae (Radix Lithospermi), Rhizoma Coptidis, the Radix Angelicae Dahuricae, Myrrha, Radix Angelicae Sinensis, Pseudobulbus Bletillae (Rhizoma Bletillae) are ministerial drug, finally it is equipped with the medicines such as Cortex Phellodendri, Rhizoma Polygoni Cuspidati, Olibanum, Borneolum Syntheticum, reaching the purpose of wound healing, and eliminate in wound healing process, some of generation are uncomfortable, such as, the symptom such as infection, pain.
nullWhen specifically preparing，First，By ready Chinese medicine component in boiling water rapid soaking filter under，Pull out the most rapidly，Drain，Quickly immersed with being beneficial to kill the antibacterial on some surfaces，And do not affect the drug effect of Chinese medicine，After Chinese medicine drains，Chinese medicine cutting is become unqualified shape，Put into the dry pot of pot to stir-fry，The purpose that dry pot stir-fries is Radix Angelicae Sinensis、Sanguis Draxonis、The active ingredient of the Chinese medicines such as Cortex Phellodendri is in the sweat in later stage，Preferably decompose out，Improve the effect of herb fermenting，After the time that stir-fries has the temperature of 30～40 DEG C with medicine，Stopping stir-fries，After waiting to stir-fry，After stir-frying, Chinese medicinal powder is put in pot，Add water，Amount of water is 2～3 times of Chinese medicine gross weight，Then slow fire boils 1 hour，After having boiled，After liquid medicine cooling in pot，Chinese medicine and the liquid medicine that boils are put into fermentation tank，Add strain，The addition of strain is the 1%～4% of Chinese medicine gross weight，In the present embodiment，It is 1%，Strain is preferably the mixture of yeast and bacillus bifidus，Can certainly be single yeast or bacillus bifidus，In the present embodiment，The mass ratio of yeast and bacillus bifidus is 1:1.5，Specifically，Bifidus bacillus is the mixed bacteria of bifidobacterium longum and bifidobacterium breve，Then seal，Then temperature 24 DEG C～28 DEG C in fermentation tank is controlled，Fermentation time is to ferment for 36 hours；After fermentation completes, take out the Chinese medicine and liquid medicine fermented, filter, obtain filtrate；Then, carrying out high temperature compressed by filtrate, being compressed to relative concentration is 1.5～1.7, i.e. obtains finished product.
Embodiment 2, the present embodiment provides a kind of wound healing Chinese medicine extraction liquid, including following active princlple: Radix Angelicae Sinensis 10 parts, Radix Sanguisorbae 20 parts, Radix Arnebiae (Radix Lithospermi) 10 parts, Radix Et Rhizoma Rhei 10 parts, Rhizoma Coptidis 15 parts, Cortex Phellodendri 10 parts, Rhizoma Polygoni Cuspidati 8 parts, Olibanum 10 parts, Herba Artemisiae Anomalae 10 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 10 parts, the Radix Angelicae Dahuricae 10 parts, Myrrha 15 parts, Cortex Meliae 10 parts, Borneolum Syntheticum 8 parts, Sanguis Draxonis 10 parts.
nullWhen specifically preparing，First，By ready Chinese medicine component in boiling water rapid soaking filter under，Pull out the most rapidly，Drain，Quickly immersed with being beneficial to kill the antibacterial on some surfaces，And do not affect the drug effect of Chinese medicine，After Chinese medicine drains，Chinese medicine cutting is become unqualified shape，Put into the dry pot of pot to stir-fry，The purpose that dry pot stir-fries is Radix Angelicae Sinensis、Sanguis Draxonis、The active ingredient of the Chinese medicines such as Cortex Phellodendri is in the sweat in later stage，Preferably decompose out，Improve the effect of herb fermenting，After the time that stir-fries has the temperature of 30～40 DEG C with medicine，Stopping stir-fries，After waiting to stir-fry，After stir-frying, Chinese medicinal powder is put in pot，Add water，Amount of water is 2～3 times of Chinese medicine gross weight，Then slow fire boils 1 hour，After having boiled，After liquid medicine cooling in pot，Chinese medicine and the liquid medicine that boils are put into fermentation tank，Add strain，The addition of strain is the 1%～4% of Chinese medicine gross weight，In the present embodiment，It is 3%，Strain is preferably the mixture of yeast and bacillus bifidus，Can certainly be single yeast or bacillus bifidus，In the present embodiment，The mass ratio of yeast and bacillus bifidus is 1:1.5，Specifically，Bifidus bacillus is the mixed bacteria of avette bacillus bifidus and bifidobacterium thermophilum，Then seal，Then temperature 24 DEG C～28 DEG C in fermentation tank is controlled，Fermentation time is to ferment for 28 hours；After fermentation completes, take out the Chinese medicine and liquid medicine fermented, filter, obtain filtrate；Then, carrying out high temperature compressed by filtrate, being compressed to relative concentration is 1.5～1.7, i.e. obtains finished product.
Embodiment 3, the present embodiment provides a kind of wound healing Chinese medicine extraction liquid, including following active princlple: Radix Angelicae Sinensis 10 parts, Radix Sanguisorbae 20 parts, Radix Arnebiae (Radix Lithospermi) 10 parts, Radix Et Rhizoma Rhei 10 parts, Rhizoma Coptidis 8 parts, Cortex Phellodendri 10 parts, Rhizoma Polygoni Cuspidati 5 parts, Olibanum 8 parts, Herba Artemisiae Anomalae 10 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 7 parts, the Radix Angelicae Dahuricae 8 parts, Myrrha 7 parts, Cortex Meliae 5 parts, Borneolum Syntheticum 6 parts, Sanguis Draxonis 10 parts.
nullWhen specifically preparing，First，By ready Chinese medicine component in boiling water rapid soaking filter under，Pull out the most rapidly，Drain，Quickly immersed with being beneficial to kill the antibacterial on some surfaces，And do not affect the drug effect of Chinese medicine，After Chinese medicine drains，Chinese medicine cutting is become unqualified shape，Put into the dry pot of pot to stir-fry，The purpose that dry pot stir-fries is Radix Angelicae Sinensis、Sanguis Draxonis、The active ingredient of the Chinese medicines such as Cortex Phellodendri is in the sweat in later stage，Preferably decompose out，Improve the effect of herb fermenting，After the time that stir-fries has the temperature of 30～40 DEG C with medicine，Stopping stir-fries，After waiting to stir-fry，After stir-frying, Chinese medicinal powder is put in pot，Add water，Amount of water is 2～3 times of Chinese medicine gross weight，Then slow fire boils 1 hour，After having boiled，After liquid medicine cooling in pot，Chinese medicine and the liquid medicine that boils are put into fermentation tank，Add strain，The addition of strain is the 1%～4% of Chinese medicine gross weight，In the present embodiment，It is 4%，Strain is preferably the mixture of yeast and bacillus bifidus，Can certainly be single yeast or bacillus bifidus，In the present embodiment，The mass ratio of yeast and bacillus bifidus is 1:1.5，Specifically，Bifidus bacillus is the mixed bacteria of avette bacillus bifidus and bifidobacterium thermophilum，Then seal，Then temperature 24 DEG C～28 DEG C in fermentation tank is controlled，Fermentation time is to ferment for 48 hours；After fermentation completes, take out the Chinese medicine and liquid medicine fermented, filter, obtain filtrate；Then, carrying out high temperature compressed by filtrate, being compressed to relative concentration is 1.5～1.7, i.e. obtains finished product.
Toxicity test
Taking ICR mice, before experiment, water 15h is can't help in fasting, is divided into 19 groups (the trial drug group of each embodiment 6 groups, matched groups 1 group).Each group mouse tail vein is administered, and tests 1 group and is the most according to dosage respectively 500mg/kg, 1000mg/kg, 2000mg/kg, 5000mg/kg, 10000mg/kg, 20000mg/kg to 6 groups of dosages of test, and control group mice gives same volume distilled water.Examine and record and be administered the toxic reaction and death condition at once occurred to mice in 7d；Bliss ' s method is used to calculate LD50.The following form of experimental result:
| Group | mg/Kg |
| Embodiment 1 group | 5970.6mg/Kg |
| Embodiment 2 group | 6078.4mg/Kg |
| Embodiment 3 group | 6540.8mg/Kg |
The LD50 of medicine is at more than 5970mg/kg as seen from the above table, it is clear that the toxicity of this medicine is the lowest, in rational range, few to the toxic and side effects of human body.
Chinese medicine extraction liquid prepared by the embodiment of the present invention may be used for the wound for the treatment of and includes: the infection of injury of human, human body thin T bacterium, skin and the hemorrhage oozing of blood of muscular tissue.Wherein injury of human includes: scratch, sword device hurts, are stabbed, blast injury (damage that shock wave causes), burn, cold injury, animal bite, chemical injury, radiation injury and above-mentioned in the damage etc. that causes of two or more combination；Human body antibacterial sense includes: epidermis or muscular tissue abscess, rotten, ulcer etc.；Skin and the hemorrhage oozing of blood of muscular tissue include: gingival hemorrhage, epistaxis etc..Using method is: daily 2～3 times, a 100ml, it is also possible to smear use.
Clinical case:
Case 1 patient female, 61 years old, careless incised wound left hand thumb palmar when cutting the dish, straight cut, injures muscle, at once pain, bleed, treatment of distal thumb can not bend, use the present invention provide Chinese medicine extraction liquid, take and be applied in wound surface in right amount, wrapping, and according to dosage take extracting solution, within three days, change a medicine, wound healing after 1 week.
Case 2 patient man, 40 years old, femoribus internus intramuscular infection produced abscess, rear incision and drainage, smear in drainage strip the present invention offer Chinese medicine extraction liquid, in right amount, wrapping, and according to dosage take extracting solution, within three days, change a medicine, wound healing after first quarter moon.
Case 3 patient female, 12 years old, hand was scalded, and used the Chinese medicine extraction liquid of the present invention, takes appropriate painting and is spread on scald wound, and after one hour, pain eliminates, and according to dosage took extracting solution, and every day 2～smear a medicine, wound healing after 4 weeks for 3 times, did not had cicatrix.
The above; it it is only presently preferred embodiments of the present invention; it it is not the restriction that the present invention is made other form; any those skilled in the art are changed possibly also with the technology contents of the disclosure above or are modified as the Equivalent embodiments of equivalent variations is applied to other field; but it is every without departing from technical solution of the present invention content; any simple modification, equivalent variations and the remodeling made above example according to the technical spirit of the present invention, still falls within the protection domain of technical solution of the present invention.
Claims (9)
1. a wound healing Chinese medicine extraction liquid, it is characterised in that include following active princlple: Radix Angelicae Sinensis,
Radix Sanguisorbae, Radix Arnebiae (Radix Lithospermi), Radix Et Rhizoma Rhei, Rhizoma Coptidis, Cortex Phellodendri, Rhizoma Polygoni Cuspidati, Olibanum, Herba Artemisiae Anomalae, Pseudobulbus Bletillae (Rhizoma Bletillae), the Radix Angelicae Dahuricae, Myrrha,
Cortex Meliae, Borneolum Syntheticum, Sanguis Draxonis.
Wound healing Chinese medicine extraction liquid the most according to claim 1, it is characterised in that according to weight
Amount number includes following active princlple: Radix Angelicae Sinensis 5 parts～10 parts, Radix Sanguisorbae 10 parts～20 parts, Radix Arnebiae (Radix Lithospermi) 5 parts～10
Part, Radix Et Rhizoma Rhei 5 parts～10 parts, Rhizoma Coptidis 7 parts～15 parts, Cortex Phellodendri 5 parts～10 parts, Rhizoma Polygoni Cuspidati 3 parts～8 parts, breast
Perfume 5 parts～10 parts, Herba Artemisiae Anomalae 5 parts～10 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 5 parts～10 parts, the Radix Angelicae Dahuricae 5 parts～10 parts, Myrrha 7
Part～15 parts, Cortex Meliae 5 parts～10 parts, Borneolum Syntheticum 2 parts～8 parts, Sanguis Draxonis 5 parts～10 parts.
Wound healing Chinese medicine extraction liquid the most according to claim 2, it is characterised in that according to weight
Amount number includes following active princlple: Radix Angelicae Sinensis 10 parts, Radix Sanguisorbae 20 parts, Radix Arnebiae (Radix Lithospermi) 10 parts, Radix Et Rhizoma Rhei 10 parts,
Rhizoma Coptidis 8 parts, Cortex Phellodendri 10 parts, Rhizoma Polygoni Cuspidati 5 parts, Olibanum 8 parts, Herba Artemisiae Anomalae 10 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 7 parts, the Radix Angelicae Dahuricae
8 parts, Myrrha 7 parts, Cortex Meliae 5 parts, Borneolum Syntheticum 6 parts, Sanguis Draxonis 10 parts.
4. the method preparing wound healing Chinese medicine extraction liquid described in above-mentioned 1～3 any one, its feature
It is, comprises the following steps:
A, by ready Chinese medicine component in boiling water rapid soaking filter under, pull out the most rapidly, drain；
B, will drain after Chinese medicine cutting become unqualified shape, in being then placed in pot, dry pot stir-fries；
C, will stir-fry after Chinese medicine put in pot, add water, slow fire boils 1 hour；
D, after liquid medicine cooling in pot, Chinese medicine and liquid medicine are put into fermentation tank, add strain, carry out sending out
Ferment；
E, after fermentation completes, take out the Chinese medicine that ferments and liquid medicine, filter, obtain filtrate；
F, carrying out high temperature compressed by filtrate, being compressed to relative concentration is 1.5～1.7, i.e. obtains finished product.
The preparation method of wound healing Chinese medicine extraction liquid the most according to claim 4, its feature exists
In, in described step c, amount of water is 2～3 times of Chinese medicine gross weight.
The preparation method of wound healing Chinese medicine extraction liquid the most according to claim 4, its feature exists
In, in described Step d, strain is the mixture of yeast and bacillus bifidus, and the amount of described interpolation strain is
The 1%～4% of Chinese medicine gross weight.
The preparation method of wound healing Chinese medicine extraction liquid the most according to claim 6, its feature exists
In, the mass ratio of described yeast and bacillus bifidus is 1:1.5.
The preparation method of wound healing Chinese medicine extraction liquid the most according to claim 7, its feature exists
In, described bacillus bifidus is bifidobacterium longum, bifidobacterium breve, avette bacillus bifidus, bifidobacterium thermophilum
In at least one probiotics.
The preparation method of wound healing Chinese medicine extraction liquid the most according to claim 4, its feature exists
In, in described Step d, controlling fermentation temperature 24 DEG C～28 DEG C in fermentation tank, fermentation time is 28～48 little
Time.
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| CN111789915A (en) * | 2020-08-31 | 2020-10-20 | 吴荣东 | External Chinese herbal medicine powder dressing for diabetic foot and preparation method thereof |
| CN114767786A (en) * | 2022-05-13 | 2022-07-22 | 中南民族大学 | External skin-generating oil for preventing and treating liquid nitrogen ultralow-temperature frostbite and preparation method and application thereof |
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Application publication date: 20160928 |