CN105963482A - Traditional Chinese medicine composition for treating gout - Google Patents
Traditional Chinese medicine composition for treating gout Download PDFInfo
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- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/90—Smilacaceae (Catbrier family), e.g. greenbrier or sarsaparilla
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Abstract
The invention relates to a traditional Chinese medicine composition for treating gout. The composition is prepared from the following raw materials in parts by weight: 18-22 parts of dioscorea nipponica, 13-17 parts of fructus polygoni orientalis, 28-32 parts of glabrous greenbrier rhizome, 18-22 parts of calcite, 18-22 parts of ramulus euonymi, 18-22 parts of yam rhizome, 13-17 parts of kuh-seng, 13-17 parts of radix sileris, 13-17 parts of semen sojae germinatum and 4-8 parts of radix glycyrrhizae preparata. The traditional Chinese medicine composition has the advantages of being good in curative effect, small in side effect and capable of thoroughly treating gout.
Description
Technical field
The invention belongs to pharmaceutical technology field, be specifically related to a kind of Chinese medicine composition treating gout.
Background technology
The general intermittent attack of gout, mainly shows as the positions such as big toe joint, ankle joint and articulations digitorum manus red and swollen during morbidity,
And be attended by acupuncture, lancinate as sharp property pain, most of patients also can occur together hyperpyrexia, and the general course of disease patient more than 5 years will
Occur gout calculus, gout calculus may result in joint gross distortion, makes patient normally to walk, even cannot taking pen, book,
The every-day objects such as chopsticks, tophus treatment meeting ulceration voluntarily not in time, wound is not healed, and is eventually compeled because of infection
Patient's amputation is made to disable.Some patients also can be super because of diseases, the especially course of disease such as gout premature coronary heart disease, hypertension, diabetes
Cross the gouty nephropathy patient of more than 10 years, if the state of an illness is not controlled by, it is easy to cause renal colic, hematuria kidney until drawing
Sending out renal failure and uremia, finally, some patients have to rely on renal transplantation to sustain life；Gouty arthritis be by
Caused by disorders of purine metabolism, serum Uric Acid Concentration increases, thus urate crystal is deposited on a kind of metabolic osteoarthrosis that joint causes
Disease, sodium urate crystals is proved to be the non-microorganism pathogen of GA, and the immune inflammation of its induction rises in the morbidity of GA
Important function, acute GA outbreak is mainly by synovial membrane inflammatory cell infiltration, uric acid deposition, tissue local necrosis, and urate in early days is tied
Brilliant shedding in synovial fluid from calm synovial membrane, the protein in synovial fluid is adsorbed in crystal surface immediately, and be synovial cell,
Multinuclear leucocyte, monocyte, macrophage are swallowed, synovial membrane surface hyperemia edema, caused by cell infiltration；At therapeutics
On, current medicine such as nonsteroidal anti-inflammatory, colchicine etc. are all heavier and clinical because of offer limited effectiveness or untoward reaction
Applying limited, therefore, the high-efficiency low-toxicity medicine continuing to explore the acute GA for the treatment of is significant.
Summary of the invention
It is an object of the invention to overcome the deficiencies in the prior art to provide the treatment that a kind of therapeutic effect is good, side effect is little
The Chinese medicine composition of gout.
The object of the present invention is achieved like this: a kind of Chinese medicine composition treating gout, described compositions is by following
Raw material by weight prepares: Rhizoma Dioscoreae Nipponicae 18-22 part, Fructus Polygoni Orientalis 13-17 part, Rhizoma Smilacis Glabrae 28-32 part, Mirabilitum crystallina 18-22 part,
Ramulus Euonymi 18-22 part, Bi 18-22 part, Radix Sophorae Flavescentis 13-17 part, Radix Saposhnikoviae 13-17 part, Semen Glycine Germinatum 13-17 part, Radix Glycyrrhizae Preparata 4-8
Part.
The Chinese medicine composition of described treatment gout is prepared by following raw material by weight: Rhizoma Dioscoreae Nipponicae 20 parts, Herba Polygoni Orientalis
Son 15 parts, Rhizoma Smilacis Glabrae 30 parts, Mirabilitum crystallina 20 parts, Ramulus Euonymi 20 parts, Bi 20 parts, Radix Sophorae Flavescentis 15 parts, Radix Saposhnikoviae 15 parts, Semen Glycine Germinatum 15
Part, Radix Glycyrrhizae Preparata 6 parts.
The Chinese medicine composition of described treatment gout is prepared by following raw material by weight: Rhizoma Dioscoreae Nipponicae 18 parts, Herba Polygoni Orientalis
Son 13 parts, Rhizoma Smilacis Glabrae 28 parts, Mirabilitum crystallina 18 parts, Ramulus Euonymi 18 parts, Bi 18 parts, Radix Sophorae Flavescentis 13 parts, Radix Saposhnikoviae 13 parts, Semen Glycine Germinatum 13
Part, Radix Glycyrrhizae Preparata 4 parts.
The invention have the advantages that the present invention based on Traditional Chinese medical theory, with reference to modern pharmacological research achievement, by Chinese medicine
Combination principle is made, and has treatment gout remarkably productive, evident in efficacy, can really take stopgap measures and effect a permanent cure, and will not recur, and the present invention has
Have abundant raw material, the advantage that cheap, drug safety, using effect are good.
The pharmacological property of each crude drug of the present invention is analyzed as follows:
1) Rhizoma Dioscoreae Nipponicae: perennial voluble herb.Rhizome horizontal walk, cylindrical, yellowish-brown.Stem is left-handed, up to 5 meters, is close to without hair, dry
Dry rhizome, star elongated cylindrical, long 10～20 centimetres, diameter about 1.5 centimetres, have most irregular branch. appearance khaki, have
Most thin longitudinal grins and the fibrous root residue of projection, full-shape is slightly like Cornu Cervi.Matter is hard, and section is faint yellow, mealiness, it is seen that most fine-mesheds
Vascular bundle be dispersed in, feeble QI, bitter in the mouth.The longest with rhizome, khaki, the hard person of matter is preferably.
Nature and flavor are put down；Bitter.Return liver；Lung meridian.
Function cures mainly: expelling wind and removing dampness；Promoting blood circulation to remove obstruction in the collateral；Cough-relieving.Before main air arthralgia chiefly caused by damp pathogen；Numb limbs and tense tendons；Obstruction of qi in the chest and cardialgia；Chronic Airway
Scorching；Traumatic injury；Malaria；Carbuncle.
2) Fructus Polygoni Orientalis: this product is the dry mature fruit of polygonaceae plant smartweed;Another name water Polygonum, Herba Polygoni Orientalis reality, river knotweed,
River knotweed, bright pink son, for the dry fruit of plant Herba Polygoni Orientalis, in oblateness, diameter 2 ~ 3 millimeters, thickness 1 ~ 1.5 millimeter.Surface is dark brown
Color, or rufous, glossy, two sides nick enters, and its central authorities are the wire of micro-protuberance, and tip has the base for post of thorn-like projection, base
There are the fruit stem trace of light brown slightly projection, sometimes residual film quality perianth in portion, and feeble QI is weak, lightly seasoned, enriches with full, and color red and black person is
Good.
Meridian distribution of property and flavor: salty, is slightly cold.Heat clearing away, softening the hard mass.
Function cures mainly: have scattered blood eliminating mass, removing food stagnancy pain relieving, inducing diuresis to remove edema function.For mass in the abdomen abdominal distention, hepatosplenomegaly, neck drenches
Fawn on core, quench one's thirst, stomachache.Consumption 4.5 ~ 9g, heavy dose can be to 30g；Suitable amount used externally is endured cream or smashes long-pending, invigorating spleen to remove dampness；Control flank
Disease is amassed, and dropsy has a stomach-ache, lack of appetite abdominal distention, acute catarrhal conjunctivitis, and skin ulcer swells, scrofula.
3) Rhizoma Smilacis Glabrae: climb shape shrub for Liliaceae perennial evergreen, part of being used as medicine only selects its dried rhizome.
Meridian distribution of property and flavor: sweet light is flat.Return Liver Channel；Stomach warp；Spleen channel.
Function cures mainly: removing toxic substances, dehumidifying, profit joint, cures mainly: control syphilis, stranguria with turbid discharge, muscles and bones spasm and pain, tinea pedis, treats furuncle, carbuncle,
Limbs contracture caused by scrofula, syphilis and mercurialism, bones and muscles pain.
4) Mirabilitum crystallina: being a kind of Ore Chinese crude drug, heat clearing and fire purging medicine, also known as Mirabilitum crystallina, water stone, magpie stone, this product is natural
Sedimentary mineral monoclinic system calcium sulfate or trigonal system calcium carbonate mineral.
Meridian distribution of property and flavor is pungent: pungent, salty, cold.GUIXIN, stomach, kidney channel.
Function cures mainly: clearing away heat-fire, profit key, detumescence, and for calentura excessive thirst, erysipelas is scalded.
5) Ramulus Euonymi: branch is elongated circle, is about 40～50cm, diameter 0.4～1cm.Rough surface, dull gray is green to ash
Green, has vertical wrinkle and canescence to indulge raw hole skin.Suberin wing 4, flat sheet-like, the thickest at nearly stem, the thinnest, wide by 4
～10mm, surface taupe brown, to dark brownish red, has fine densification to indulge straight burr or wavy bending texture, the existing horizontal dimpled grain having.
Branch is hard and tough, section yellowish white, fibroid, feeble QI, mildly bitter flavor.Wing light weight is crisp, and section is smooth, brown color, fine grained,
Feeble QI, taste is micro-puckery
Nature and flavor with return through: cold in nature, bitter in the mouth.Return Liver Channel.
Function with cure mainly: promoting blood circulation to remove blood stasis, parasite killing.For amenorrhea, postnatal blood stasis stomachache, abdominal pain due to worm stagnation.
6) Bi: rhizome is Bamboo-shaped, and class is cylindrical, has branch, surface shrinkage, often remains stem and withers cicatrix and not eliminating
Most elongated fibrous root.Commodity mostly are irregular thin slice, not of uniform size, thickness about 0.5mm, and edge is irregular, and have has brownish black
Or the crust of taupe brown.Tangent plane yellow-white or light taupe brown, smooth, fine and smooth, there are mealiness and irregular yellow muscle arteries and veins decorative pattern (dimension
Tube bank), illumination is regarded, significantly.Matter pine, frangibility.Feeble QI, taste base, micro-pungent., tangent plane yellow-white person big and thin with sheet is
Good.
Nature and flavor are put down through: property with returning, bitter in the mouth.Return Liver Channel, stomach warp, bladder warp.
Function with cure mainly: rheumatic arthralgia；Stranguria with turbid discharge；Skin ulcer rash pruritus；Ecthyma.
7) Radix Sophorae Flavescentis: the mutation belonged to for pulse family Radix Sophorae Flavescentis.It is distributed in Russia, Japan, India, Korea and China's Mainland etc.
Ground, is grown on height above sea level 1, the area of 500 meters, and many lifes are in hillside, sand ground grass slope spinney and near field, the most not yet by people
Work introducing and planting.
Nature and flavor with return through bitter in the mouth；Cold in nature.Return liver；Kidney；Large intestine；Small intestine meridian；Bladder；Heart channel；Bladder warp.
Function with cure mainly: heat clearing and damp drying；Wind dispelling insecticide.Main damp-heat dysentery；Discharging fresh blood stool；Jaundice；Dysuria；Edema；
Leukorrhagia；Pudendal pruritus；Scabies；Leprosy；Skin pruritus；Noxious dampness skin infection.
8) Radix Saposhnikoviae: Radix Saposhnikoviae is Chinese crude drug, is the root of Umbelliferae herbaceos perennial Radix Saposhnikoviae.
Nature and flavor with return through: acrid in the mouth, sweet, slightly warm in nature.Return bladder, liver, spleen channel.
Function with cure mainly: expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion jerks surely, diseases caused by exogenous pathogenic factor exterior syndrome, rubella pruritus, rheumatic arthralgia, broken wound
Wind.
9) Semen Glycine Germinatum: forming for drying after the germination of legume soybean, autumn gathers, puts shady and cool dry after shelling
Dry place, standby.
Nature and flavor with return through: property is sweet, flat；Return spleen, stomach warp.
Function with cure mainly: have removing summer-heat pathogenic factor in the exterior, the function of point dampness removing heat.Control hygropyrexia from the beginning of, damp and hot do not change, antiperspirant is few, the feeling of stuffiness in chest, water
Swelling is full, dysuria, arthralgia chiefly caused by damp pathogen, clonic spasm of the muscle, arthralgia with restlessness.
10) Radix Glycyrrhizae Preparata: be leguminous plant, Radix Glycyrrhizae Preparata is the Radix Glycyrrhizae baked with honey, is commonly called as concocting, it is simply that put in pot by Mel
Being smelt middle honey, use slow fire instead and add Radix Glycyrrhizae sheet and stir uniformly, 3 ~ 5 min take the dish out of the pot, and put barn or time baking oven 60 ~ C is dried to tack-free
Taking out, cool, Radix Glycyrrhizae Preparata is similar round or oval section, and surface red brown or taupe brown are micro-glossy, tangent plane yellow
To buff, cambium ring is obvious, ray irradiation shape.
Nature and flavor with return through sweet in the mouth, flat.GUIXIN, lung, spleen, stomach warp.
Function with cure mainly: spleen reinforcing stomach function regulating, Yiqi and vein recovery.For weakness of the spleen and stomach, fatigue and weakness, severe palpitation, irregularly intermittent and regularly intermittent pulse, can solve
Radix Aconiti Lateralis Preparata poison.
Specific embodiment
Below in conjunction with embodiment, the present invention is further illustrated.
Embodiment
In the specific implementation, the Chinese medicine composition for the treatment of gout is prepared the present invention by following raw material by weight: wear mountain
Dragon 18 parts, Fructus Polygoni Orientalis 13 parts, Rhizoma Smilacis Glabrae 28 parts, Mirabilitum crystallina 18 parts, Ramulus Euonymi 18 parts, Bi 18 parts, Radix Sophorae Flavescentis 13 parts, Radix Saposhnikoviae 13
Part, Semen Glycine Germinatum 13 parts, Radix Glycyrrhizae Preparata 4 parts.
The present invention, based on Traditional Chinese medical theory, with reference to modern pharmacological research achievement, is made by drug matching principle, has and control
Treatment gout is remarkably productive, evident in efficacy, can really take stopgap measures and effect a permanent cure, and will not recur, and it is low that the present invention has abundant raw material, price
Advantage honest and clean, that drug safety, using effect are good.
Claims (3)
1. the Chinese medicine composition treating gout, it is characterised in that: described compositions is by following raw material system by weight
: Rhizoma Dioscoreae Nipponicae 18-22 part, Fructus Polygoni Orientalis 13-17 part, Rhizoma Smilacis Glabrae 28-32 part, Mirabilitum crystallina 18-22 part, Ramulus Euonymi 18-22 part, Bi
18-22 part, Radix Sophorae Flavescentis 13-17 part, Radix Saposhnikoviae 13-17 part, Semen Glycine Germinatum 13-17 part, Radix Glycyrrhizae Preparata 4-8 part.
A kind of Chinese medicine composition treating gout, it is characterised in that: described compositions is by following
Raw material by weight prepares: Rhizoma Dioscoreae Nipponicae 20 parts, Fructus Polygoni Orientalis 15 parts, Rhizoma Smilacis Glabrae 30 parts, Mirabilitum crystallina 20 parts, Ramulus Euonymi 20 parts,
Bi 20 parts, Radix Sophorae Flavescentis 15 parts, Radix Saposhnikoviae 15 parts, Semen Glycine Germinatum 15 parts, Radix Glycyrrhizae Preparata 6 parts.
A kind of Chinese medicine composition treating gout, it is characterised in that: described compositions is by following
Raw material by weight prepares: Rhizoma Dioscoreae Nipponicae 18 parts, Fructus Polygoni Orientalis 13 parts, Rhizoma Smilacis Glabrae 28 parts, Mirabilitum crystallina 18 parts, Ramulus Euonymi 18 parts,
Bi 18 parts, Radix Sophorae Flavescentis 13 parts, Radix Saposhnikoviae 13 parts, Semen Glycine Germinatum 13 parts, Radix Glycyrrhizae Preparata 4 parts.
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| CN108186720A (en) * | 2018-03-26 | 2018-06-22 | 成都中医药大学 | A kind of pharmaceutical composition and its preparation method and application |
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| CN104689173A (en) * | 2015-03-13 | 2015-06-10 | 青岛大学附属医院 | Traditional Chinese medicine compound preparation for treating gout |
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| CN104689173A (en) * | 2015-03-13 | 2015-06-10 | 青岛大学附属医院 | Traditional Chinese medicine compound preparation for treating gout |
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| 唐奇志: "渗湿定痛汤治疗急性痛风性关节炎60例临床研究", 《新中医》 * |
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| CN108186720A (en) * | 2018-03-26 | 2018-06-22 | 成都中医药大学 | A kind of pharmaceutical composition and its preparation method and application |
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Application publication date: 20160928 |