CN104489686B - Chemotherapy is had health care medicated diet and the preparation of potentiation - Google Patents
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Abstract
The invention discloses a kind of health care medicated diet that chemotherapy is had potentiation and preparation method thereof, take off and state the primary raw material medicine of weight proportion and be prepared from: the Radix Astragali 15 25, Semen Coicis 12 20, Rhizoma Dioscoreae 10 20, Rhizoma Polygonati 9 15, Rhizoma Chuanxiong 8 16, Herba Cirrohopetali Andersonii 8 12, Fructus Trichosanthis 6 15, Hericium erinaceus (Bull. Ex Fr.) Pers. 8 16, Herba Hedyotidis Diffusae 69, Testis et Pentis Canis 10 15, Carnis Pseudosciaenae 20 35, Radix Glycyrrhizae 9 15, Gallus Domesticus 45 60.The present invention can alleviate patient suffering, effectively extends the survival of patients time, promotes quality of life；Combined with chemotherapy can substantially alleviate chemotherapy toxic side effect, helps chemotherapy to smoothly complete, chemotherapy is had potentiation.
Description
Technical field
The present invention relates to field of food health care, particularly relate to a kind of health care medicated diet that chemotherapy is had potentiation and preparation.
Background technology
At present, tumor has become as another Health Killer after cardiovascular disease.Along with going deep into of clinical research, the treatment of current cancer has become multi-disciplinary Comprehensive Treatment, has the methods such as operation, radiotherapy, chemotherapy, biological immune treatment, traditional Chinese medical herbal treatment, endocrine therapy, thermotherapy, optical dynamic therapy, cold therapy and therapy of tumor.Wherein, chemotherapy is one of most common method.But, toxic and side is relatively big, particularly has an impact immune function of human body, and some medicines also have toxicity at a specified future date.Serious general reaction, digestive tract reaction, bone marrow depression etc., be to be related to the key that can chemotherapy smoothly complete.One, general reaction.Cardinal symptom has dizziness, dim eyesight, fatigue and weak, listless, inappetence, defecation imbalance etc..Chinese medical discrimination many genus QI and blood deficiency, the symptom of deficiency of both the liver and kidney.Treat suitable benefiting qi and nourishing blood, nourishing the liver and kidney.Conventional BAZHEN TANG, liter blood adjust unit's soup (Radix Astragali, Radix Codonopsis, Rhizoma Drynariae, Fructus Ligustri Lucidi etc.).Two, digestive tract reaction, nausea and vomiting.Nausea and vomiting is the untoward reaction that chemotherapy is commonplace, and often leading to patient cannot take food, and even affects continual cure.Correlational study is a lot, adds, with Chinese medicine, the nausea and vomiting that ondansetron prevention cisplatin causes, respond well.1, vomiting clear water person belongs to Deficiency and coldness of spleen and stomach, and the card of stomach-QI being unable to descend normally treats suitable invigorating the spleen and regulating the stomach, stopping nausea and vomiting by lowering the adverse flow of QI.Conventional Chenxialiujunzi medicinal soup closes Flos Caryophylli persimmon calyx powder plus-minus (Pericarpium Citri Reticulatae, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Poria, Radix Glycyrrhizae Preparata, Radix Codonopsis, Calyx Kaki etc.).2, acid regurgitation, misery person belong to the card of gastric heat, preferably use Tangerine Peel and Bamboo Shavings Decoction (Pericarpium Citri tangerinae, Caulis Bambusae In Taenia, Fructus Jujubae, Radix Codonopsis etc.).3, gastral cavilty is glutted, the breast side of body alters pain person, the card of genus incoordination between the liver and stomach, preferably adds and subtracts by XIAOYAO POWDER., often there is stomachache, diarrhoea, dysporia, mucosa necrosis, ulcer, bleeder even occurs, Chinese medical discrimination many genus taste are lacked of proper care in abdominal pain diarrhea in chemotherapy process.Stomachache can take Radix Glycyrrhizae Radix Paeoniae Decoction (Radix Paeoniae Alba, Radix Glycyrrhizae, Fructus Citri Sarcodactylis, Poria, the Radix Aucklandiae etc.)；The available banxia xiexin decoction (Rhizoma Pinelliae Preparatum, Rhizoma Coptidis, Radix Scutellariae, Rhizomadioscoreae, the Rhizoma Atractylodis Macrocephalae) of diarrhoea.Three, bone marrow depression.Most antitumor drug can cause bone marrow depression in various degree, shows as leukopenia, resistance decline, and the situations such as anemia occurs in severe patient, and wherein small number of patients can not recover normal for many years.Therefore, a big problem during bone marrow depression is chemotherapy.Preferably coordinate treatment by Chinese herbs during whole chemotherapy, to alleviate the toxicity of chemotherapeutic, protect bone marrow, the recovery of hemopoietic and reconstruction.The traditional Chinese medical science is thought, " taste biochemistry QI and blood " " kidney governing bones " " the raw marrow of bone ", and invigorating the spleen and benefiting QI, kidney tonifying, essence replenishing is that righting rises white key.Rise blood soup and have good curative effect in this respect.Liter blood soup: the Radix Astragali, Radix Pseudostellariae, the Rhizoma Atractylodis Macrocephalae, Poria, Caulis Spatholobi, Semen Cuscutae etc..Prescription is comprehensive, evident in efficacy.Four, immunologic function degression.Most antitumor drug have inhibitory action in various degree to the immunologic function of body.Improve the medicine of immunologic function, currently used most be polysaccharide (Lentinus Edodes, Polyporus, Poria, Ganoderma, Auricularia etc.).Qi-tonifying drug in Chinese medicine such as Radix Ginseng, the Radix Astragali, Ganoderma etc., drugs for nourishing yin such as Fructus Ligustri Lucidi, Fructus Corni, the Radix Rehmanniae etc., part promoting blood flow and remove blood stasis drug such as Rhizoma Curcumae, Radix Notoginseng etc., heat and toxic materials clearing away medicine such as Herba Hedyotidis Diffusae, Herba Taraxaci, Rhizoma Coptidis etc., all there is immunological enhancement, can diagnosis and prescription.Five, neurotoxicity.Part chemotherapeutics such as vinblastine, vincristine etc., have obvious toxic action to peripheral nerve, shows as that distal limbs sensory disturbance, tendon reflex be low and enteroparalysis etc..The traditional Chinese medical science is thought, the numb limbs and tense tendons that peripheral nerve toxicity causes belongs to " arthromyodynia " category.Huangdi's Internal Classics: " coagulation of blood in skin giving rise to numbness ", " its most meciless person, disease enters deeply for a long time, and Rong Wei trip is puckery, dredges, therefore the most bitterly, skin is not sought, therefore be meciless during meridians ".Therefore, Chinese traditional treatment is based on benefiting QI and nourishing blood, activating blood circulation to dissipate blood stasis.The medicines such as the Radix Astragali, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Caulis Spatholobi, Flos Carthami can be used with promoting blood circulation to remove obstruction in the collateral.Six, mucosa reaction.Some chemotherapeutics can cause various mucosa reaction, as congested in stomatitis, oral ulcer, esophagus or gastrointestinal tract mucosa etc..At most see stomatocace.Chinese traditional treatment is based on heat-clearing and toxic substances removing, nourishing YIN and benefiting blood.Dialectical can use the medicines such as Flos Lonicerae, Herba Taraxaci, Radix Ophiopogonis, the Rhizoma Anemarrhenae, Radix Rehmanniae, and add SHANGLIAOHOUFENG SAN local topical.Seven, hand-foot syndrome.Hand-foot syndrome is also called palm sole of the foot sensory deprivation erythema, mainly show as finger or the heat of toe, bitterly, erythematous swelling, severe patient is developed to desquamation, ulcer and has an intense pain.Treated with Chemotherapeutic Drugs thing can cause hand-foot syndrome, such as cytosine arabinoside, cyclophosphamide, Docetaxel, vinorelbine etc..In recent years, the hand-foot syndrome caused by capecitabine is particularly acute, and has caused the attention of people.Capecitabine dependency hand-foot syndrome incidence rate is 48%-62%, often leads to drug withdrawal or decrement, has a strong impact on curative effect and reduces the quality of life of patient, has been found to as the restricted toxicity of chronic dose.Patient, during chemotherapy, should reduce the damage probability of hands, skin of foot as far as possible, and wearable loose footgear, glove, to avoid brothers frequently to rub and excessive compression.Vitamin B6 can be taken, it is also possible to be coated with outward urea frost.The curative effect of external washout with traditional Chinese herbs is the most more satisfactory (the medicine decoction being used as a lotion such as Radix Paeoniae Rubra, Cortex Dictamni, the Fructus Kochiae, Radix Saposhnikoviae, Flos Carthami, Periostracum Cicadae, Flos Lonicerae).
Application publication number CN 103070392 A(application number
Chinese patent literature 201210574978.X) discloses a kind of nutrient and healthcare products lowering electricity chemotherapy side effect, the nutrient and healthcare products lowering electricity chemotherapy side effect of the present invention, is formed including dance young pilose antler extract, the Fructus Lycii extract of certain proportional quantity.Application publication number CN
103960710 A(application publication number CN 103960710 A) Chinese patent literature disclose a kind of health promoting decoction alleviating Chemotherapy of Tumor Patients gastrointestinal reaction, mainly take off and state the raw material of weight proportion and be prepared from: Tremella 4-10 part, Aloe 2-5 part, Folium Ginseng 1-4 part, Fructus Toosendan 1.5-6 part, Bulbus Lilii 2-6 part, Semen Pruni (stir-fry) 2-6 part, Fructus Aurantii (parched) 3-7 part.Application publication number CN 102743639 A (application number
201210227299.5) Chinese patent literature discloses a kind of health composition improving chemotherapy patients's appetite, is made up of following raw material: the Radix Astragali 40～70g, Radix Ophiopogonis 15～40g, Rhizoma Gastrodiae 10～15g, the Rhizoma Atractylodis Macrocephalae 10～25g, Poria 5～10g, Ganoderma spore powder 5～10g, Fructus Lycii 15～25g, Semen Raphani 15～25g, Rhizoma Pinelliae Preparatum 15～25g, Flos Caryophylli 10～25g, Pericarpium Citri Reticulatae 10～25g, Herba bromi japonici 1000～3000g.
Chemotherapy both can anticancer, but also can kill normal cell, make quality of life decline, and the toxic and side effects that Chang Yin is in various degree, cause some patients and can not smoothly complete each course for the treatment of, have impact on curative effect.
Summary of the invention
For the deficiencies in the prior art, it is an object of the invention to provide a kind of health care medicated diet that chemotherapy is had potentiation and preparation.The present invention can alleviate patient suffering, effectively extends the survival of patients time, promotes quality of life；Combined with chemotherapy can substantially alleviate chemotherapy toxic side effect, helps chemotherapy to smoothly complete, chemotherapy is had potentiation.
The technical scheme is that
Chemotherapy is had the health care medicated diet of potentiation, takes off and state the primary raw material medicine of weight proportion and be prepared from: Radix Astragali 15-25, Semen Coicis 12-20, Rhizoma Dioscoreae 10-20, Rhizoma Polygonati 9-15, Rhizoma Chuanxiong 8-16, Herba Cirrohopetali Andersonii 8-12, Fructus Trichosanthis 6-15, Hericium erinaceus (Bull. Ex Fr.) Pers. 8-16, Herba Hedyotidis Diffusae 6-9, Testis et Pentis Canis 10-15, Carnis Pseudosciaenae 20-35, Radix Glycyrrhizae 9-15, Gallus Domesticus 45-60.
Have the health care medicated diet of potentiation to chemotherapy, preferred scheme is, takes off and states the primary raw material medicine of weight proportion and be prepared from: Radix Astragali 17-22, Semen Coicis 15-18, Rhizoma Dioscoreae 13-17, Rhizoma Polygonati 11-13, Rhizoma Chuanxiong 10-14, Herba Cirrohopetali Andersonii 9-11, Fructus Trichosanthis 8-12, Hericium erinaceus (Bull. Ex Fr.) Pers. 10-13, Herba Hedyotidis Diffusae 6.5-8, Testis et Pentis Canis 12-14, Carnis Pseudosciaenae 27-32, Radix Glycyrrhizae 11-14, Gallus Domesticus 48-56.
Have the health care medicated diet of potentiation to chemotherapy, scheme more preferably is, takes off and states the primary raw material medicine of weight proportion and be prepared from: the Radix Astragali 19, Semen Coicis 17, Rhizoma Dioscoreae 15, Rhizoma Polygonati 12, Rhizoma Chuanxiong 12, Herba Cirrohopetali Andersonii 10, Fructus Trichosanthis 10, Hericium erinaceus (Bull. Ex Fr.) Pers. 11, Herba Hedyotidis Diffusae 7, Testis et Pentis Canis 12.5, Carnis Pseudosciaenae 29, Radix Glycyrrhizae 13, Gallus Domesticus 52.
Above-mentioned have the keep healthy preparation method of medicated diet of potentiation and be chemotherapy:
(1) being cleaned by Carnis Pseudosciaenae, gill, fish body is cut sth. askew two cuttves, puts salt applied, pickles 8-16 hour；
(2) by Gallus Domesticus unhairing and internal organs, wash clean, it is cut into small pieces, puts in boiling water and roll 4-12 minute, pick up and drain the water；
(3) Radix Astragali, Rhizoma Polygonati, Rhizoma Chuanxiong, Herba Cirrohopetali Andersonii, Fructus Trichosanthis, Hericium erinaceus (Bull. Ex Fr.) Pers., Herba Hedyotidis Diffusae and Radix Glycyrrhizae are cleaned respectively, tighten in then medicine is loaded gauze bag；
(4) putting in saucepan by step (1) and step (2) gained, add water, amount of water is Carnis Pseudosciaenae and 3-4.5 times of Gallus Domesticus gross weight, step (3) gained medicated bag is put in big fire after boiling, beat offscum after boiling, put into refined salt, monosodium glutamate, onion parts, add a cover and change low baking temperature pot 25-40 minute；
(5) Testis et Pentis Canis is cleaned section, tighten in Rhizoma Dioscoreae is loaded gauze bag, put into together with Semen Coicis in above-mentioned pot, add a cover continuation pot 50-70 minute, pick medicated bag, to obtain final product.
Preferably it is in step (1), pickles 10-14 hour.
Preferably it is in step (2), puts in boiling water and roll 5-9 minute.
Preferably being in step (4), amount of water is Carnis Pseudosciaenae and 3.5-4 times of Gallus Domesticus gross weight.
Preferably it is in step (4), adds a cover and change low baking temperature pot 28-35 minute.
Preferably it is in step (5), adds a cover continuation pot 55-65 minute.
More preferably, in step (1), 12 hours are pickled.
More preferably, in step (2), put in boiling water and roll 7 minutes.
More preferably, in step (4), amount of water is 3.8 times of Carnis Pseudosciaenae and Gallus Domesticus gross weight.
More preferably, in step (4), add a cover and change low baking temperature pot 32 minutes.
More preferably, in step (5), add a cover continuation pot 60 minutes.
What the present invention provided has the health care medicated diet preparation simplicity of potentiation to chemotherapy.In addition, the excellent results of the present invention is also manifested by:
1, alleviate patient suffering, effectively extend the survival of patients time, promote quality of life；
2, there is the effects such as invigorating QI to consolidate the body surface resistance, spleen reinforcing nourishing the stomach, nourishing YIN and moistening the lung, blood-activating and qi-promoting, heat-clearing and toxic substances removing, invigorating the liver and kidney, replenishing QI and blood, facilitation protected to body's immunity, enhance ability of self contending with, thus reach to make chemotherapeutic sensitivity purpose；
3, combined with chemotherapy of the present invention can substantially alleviate chemotherapy toxic side effect, helps chemotherapy to smoothly complete；
4, medicine source is easy to get；
5, allowing patient obtain treatment in enjoying delicious food, patient is prone to accept；
6, safely, effectively, have no side effect.
Detailed description of the invention
Describe technical scheme in detail below in conjunction with embodiment and experimental example, but protection domain is not limited to this.
Used by the present invention, the pharmacology of main raw material of Chinese medicine is as follows:
The Radix Astragali: base: for leguminous plant Radix Astagali or the dry root of Radix Astragali.The property of medicine: sweet, temperature.Return lung, spleen channel.Function cures mainly: invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and bursts for a long time and does not holds back, blood deficiency dull yellowish colored skin, and interior-heat is quenched one's thirst, chronic nephritis proteinuria, diabetes.
Semen Coicis: have another name called Semen Coicis, Semen Coicis, NLIUGU, base: for the kernel of grass Semen Coicis.The property of medicine: sweet light, be slightly cold, nontoxic.Return spleen, stomach, lung, large intestine channel.Function cures mainly: clearing away heat-damp and promoting diuresis, except rheumatism, diuresis, lung benefiting evacuation of pus, strengthening the spleen and stomach, bone and muscle strengthening.Curing mainly rheumatism general pain, hygropyretic beriberi, damp and hot muscular contracture contracture, arthralgia chiefly caused by damp pathogen, edema, lung withers lung abscess, coughs vomiting bloody pus, sore throat carbuncle, acute appendicitis pyretic stranguria.
Rhizoma Dioscoreae: base: this product is the dry rhizome of Dioscoreaceae plant Rhizoma Dioscoreae.The property of medicine: sweet, flat.Return spleen, lung, kidney channel.Function cures mainly: spleen reinforcing nourishing the stomach, and promote the production of body fluid lung benefiting, the kidney invigorating arresting seminal emission.For insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung breathes with cough, and emission due to deficiency of the kidney, leukorrhagia, frequent micturition, deficiency-heat is quenched one's thirst.Rhizoma Dioscoreae (parched with bran) spleen reinforcing stomach invigorating.For insufficiency of the spleen lack of appetite, loose stool of having loose bowels, leukorrhagia.
Rhizoma Polygonati: base: for Liliaceae HUANGJING ZANYU CAPSULE Rhizoma Polygonati, Polygonatum cyrtonema Hua and the rhizome of P. kingianum.The property of medicine: sweet, flat.Return spleen, lung, kidney channel.Function cures mainly: nourishing YIN and moistening the lung, invigorating the spleen and replenishing QI, Zishen fill fine.Cure mainly deficiency of YIN chronic cough, xeropulmonary cough；Insufficiency of the spleen weak, lack of appetite xerostomia, quench one's thirst；Deficiency of the kidney soreness of the waist and knees, impotence and seminal emission, tinnitus mesh is dark, and early whitening of beard and hair, body weakness with emaciation is thin, wind favus disease.
Rhizoma Chuanxiong: base: for the dry rhizome of samphire Rhizoma Chuanxiong.The property of medicine: pungent, temperature.Return liver, gallbladder, pericardium channel.Function cures mainly: blood-activating and qi-promoting, wind-expelling pain-stopping.For menoxenia. amenorrhea dysmenorrhea, abdominal mass stomachache, breast side of body twinge, tumbling and swelling, headache, rheumatic arthralgia.
Herba Cirrohopetali Andersonii: base: for the herb that the orchid family volume lobe epidendrum comb cap volume lobe is blue.Composition: herb composition Han bibenzyl: volume lobe orchid bibenzyl is surely peaceful, big aspidistra phenol, volume lobe orchid bibenzyl is fixed, and volume lobe orchid bibenzyl is peaceful, batatasins；Also containing luxuriant and rich with fragrance constituents: volume lobe Lan Feiding, roll up lobe Lan Feiling.The property of medicine: temperature, sweet, nontoxic.Function cures mainly: expelling wind and removing dampness, invigorates blood circulation, cough-relieving, helps digestion long-pending.Curing mainly rheumatic arthralgia, traumatic injury, cough is spitted blood, food stagnation, asthenia.
Fructus Trichosanthis: another name Fructus Trichosanthis, Gua Lou, medicine melon, for Cucurbitaceae Trichosanthes Fructus Trichosanthis and the fruit of trichosanthes rosthornii Harms.The property of medicine: hardship sweet, micro-, cold.Return lung, stomach, large intestine channel.Function cures mainly: removing heat-phlegm, and relieving stuffiness of the chest by dispersing aggregation of pathogens moisturizes laxation.Cure mainly cough due to lung-heat, the thoracic obstruction, blocked-up chest, quench one's thirst, constipation, carbuncle sore tumefacting virus.
Hericium erinaceus (Bull. Ex Fr.) Pers.: another name monkey mushroom, hedgehog bacterium, Rrinaceus earopaeus bacterium, Hericium caput-medusae, Hericium erinaceus (Bull. Ex Fr.) Pers., for hedgehog fungus section fungus Hericium erinaceus (Bull. Ex Fr.) Pers., the sporophore of Hydnum.The property of medicine: sweet, flat.Return spleen, stomach warp.Function cures mainly: strengthening the spleen and nourishing the stomach, calms the nerves, anticancer.Main body void is weak, dyspepsia, insomnia, gastroduodenal ulcer, chronic gastritis, digestive tract tumor.
Herba Hedyotidis Diffusae: base: for the whole herb with root of Radix Rubiae kind plant Herba Hedyotidis Diffusae.Chemical analysis: separate 1 alkane, stigmasterol, ursolic acid, oleanolic acid, cupreol, cupreol-D-Glucose glycoside, P-coumaric acid etc. in herb.The property of medicine: bitter, sweet, cold." Guangxi Chinese medicinal herbal ": " entering the heart, liver, spleen three warp " function cures mainly: heat clearing away, dampness removing, removing toxic substances.Control dyspnea and cough due to lung-heat, tonsillitis.Pharyngolaryngitis, appendicitis, dysentery, urinary tract infection, jaundice, hepatitis, pelvic inflammatory disease, adnexitis, carbuncle furuncle, venom, tumor.Also can be used for alimentary tract cancer.
Testis et Pentis Canis: base: for the kidney of Canis animals Canis familiaris L..Chemical analysis: containing androgen, protein, fat.The property of medicine: sweet, salty, temperature.Return kidney channel.Function cures mainly: the kidney invigorating warming YANG.Main coldness of the body of suffering from a deficiency of the kidney.
Carnis Pseudosciaenae: base: belong to the meat of animal Carnis Pseudosciaenae and Carnis Pseudosciaenae for Sciaenidae Channa argus.Composition: use part containing protein, fat, moisture, calcium, phosphorus, ferrum, sulphuric acid element, riboflavin, nicotinic acid, iodine etc..The property of medicine: sweet, salty, flat.Return stomach, liver, kidney channel.Function cures mainly: QI invigorating nourishing the stomach, the kidney invigorating, improving eyesight.Cure mainly after being ill, puerperal asthenia, hypogalactia, lumbago due to renal deficiency, edema, blurring of vision.
Radix Glycyrrhizae: base: for the dry root and rhizome of glycyrrhizic legume, Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L..The property of medicine: sweet, flat.GUIXIN, lung, spleen, stomach warp.Function cures mainly: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, institute's abdomen, extremity contraction urgency pain, carbuncle sore tumefacting virus, cushion toxicity, strong.
Gallus Domesticus: base: go the entirety of feather and internal organs for Phasianidae animal Gallus Domesticus.Chemical analysis: the elements such as cupric, zinc, manganese, also containing carotene, Gallus Domesticus melanocyte etc..Pharmacological action: eating Os Gallus Domesticus can enhancing human body immunity function.The property of medicine: sweet, flat.Return liver, kidney, lung meridian.Function cures mainly: invigorating the liver and kidney, replenishing QI and blood, reducing the asthenic fever.Main asthenia is won thin, and steaming bone and consumptive fever is quenched one's thirst, seminal emission, chronic diarrhea, chronic dysentery, metrorrhagia, leukorrhagia.
Embodiment 1Have the health care medicated diet of potentiation to chemotherapy, the primary raw material medicine taking following weight parts is prepared from (every part is 20g): the Radix Astragali 15 parts, Semen Coicis 12 parts, Rhizoma Dioscoreae 10 parts, Rhizoma Polygonati 9 parts, Rhizoma Chuanxiong 8 parts, Herba Cirrohopetali Andersonii 8 parts, Fructus Trichosanthis 6 parts, Hericium erinaceus (Bull. Ex Fr.) Pers. 8 parts, Herba Hedyotidis Diffusae 6 parts, Testis et Pentis Canis 10 parts, Carnis Pseudosciaenae 20 parts, 9 parts of Radix Glycyrrhizae, Gallus Domesticus 45 parts.
Above-mentioned have the keep healthy preparation method of medicated diet of potentiation and be chemotherapy:
(1) being cleaned by Carnis Pseudosciaenae, gill, fish body is cut sth. askew two cuttves, puts salt applied, pickles 8 hours；
(2) by Gallus Domesticus unhairing and internal organs, wash clean, it is cut into small pieces, puts in boiling water and roll 4 minutes, pick up and drain the water；
(3) Radix Astragali, Rhizoma Polygonati, Rhizoma Chuanxiong, Herba Cirrohopetali Andersonii, Fructus Trichosanthis, Hericium erinaceus (Bull. Ex Fr.) Pers., Herba Hedyotidis Diffusae and Radix Glycyrrhizae are cleaned respectively, tighten in then medicine is loaded gauze bag；
(4) putting in saucepan by step (1) and step (2) gained, add water, amount of water is 3 times of Carnis Pseudosciaenae and Gallus Domesticus gross weight, step (3) gained medicated bag is put in big fire after boiling, beat offscum after boiling, put into refined salt, monosodium glutamate, onion parts, add a cover and change low baking temperature pot 25 minutes；
(5) Testis et Pentis Canis is cleaned section, tighten in Rhizoma Dioscoreae is loaded gauze bag, put into together with Semen Coicis in above-mentioned pot, add a cover continuation pot 50 minutes, pick medicated bag, to obtain final product.
Chemotherapy of the present invention has the using method of the health care medicated diet of potentiation: food meat is eaten soup, every day twice.
Embodiment 2 Have the health care medicated diet of potentiation to chemotherapy, the primary raw material medicine taking following weight parts is prepared from (every part is 20g): the Radix Astragali 25 parts, Semen Coicis 20 parts, Rhizoma Dioscoreae 20 parts, Rhizoma Polygonati 15 parts, Rhizoma Chuanxiong 16 parts, Herba Cirrohopetali Andersonii 12 parts, Fructus Trichosanthis 15 parts, Hericium erinaceus (Bull. Ex Fr.) Pers. 16 parts, Herba Hedyotidis Diffusae 9 parts, Testis et Pentis Canis 15 parts, Carnis Pseudosciaenae 35 parts, 15 parts of Radix Glycyrrhizae, Gallus Domesticus 60 parts.
Above-mentioned have the keep healthy preparation method of medicated diet of potentiation and be chemotherapy:
(1) being cleaned by Carnis Pseudosciaenae, gill, fish body is cut sth. askew two cuttves, puts salt applied, pickles 16 hours；
(2) by Gallus Domesticus unhairing and internal organs, wash clean, it is cut into small pieces, puts in boiling water and roll 12 minutes, pick up and drain the water；
(3) Radix Astragali, Rhizoma Polygonati, Rhizoma Chuanxiong, Herba Cirrohopetali Andersonii, Fructus Trichosanthis, Hericium erinaceus (Bull. Ex Fr.) Pers., Herba Hedyotidis Diffusae and Radix Glycyrrhizae are cleaned respectively, tighten in then medicine is loaded gauze bag；
(4) putting in saucepan by step (1) and step (2) gained, add water, amount of water is 4.5 times of Carnis Pseudosciaenae and Gallus Domesticus gross weight, step (3) gained medicated bag is put in big fire after boiling, beat offscum after boiling, put into refined salt, monosodium glutamate, onion parts, add a cover and change low baking temperature pot 40 minutes；
(5) Testis et Pentis Canis is cleaned section, tighten in Rhizoma Dioscoreae is loaded gauze bag, put into together with Semen Coicis in above-mentioned pot, add a cover continuation pot 70 minutes, pick medicated bag, to obtain final product.
Model case one:XXX, man, 59 years old.Suffer from nasopharyngeal carcinoma, chemotherapy four times.Pain in the lumbar region recently, to local hospital inspection, doctor says and has occurred in that Bone tumour.Due to chemotherapy, causing patient to eat does not has appetite, and health is more empty.Using the present invention to have the health care medicated diet of potentiation to chemotherapy, food meat is eaten soup, every day twice.After taking two weeks, having a meal and have an appetite, health takes a turn for the better.After taking 1 month, again carry out chemotherapy, and chemotherapy smoothly completes, do not have when chemotherapy any untoward reaction, health to recover steadily.After 2 months, check metastatic lesion has disappeared.
Embodiment 3Have the health care medicated diet of potentiation to chemotherapy, the primary raw material medicine taking following weight parts is prepared from (every part is 20g): the Radix Astragali 17 parts, Semen Coicis 15 parts, Rhizoma Dioscoreae 13 parts, Rhizoma Polygonati 11 parts, Rhizoma Chuanxiong 10 parts, Herba Cirrohopetali Andersonii 9 parts, Fructus Trichosanthis 8 parts, Hericium erinaceus (Bull. Ex Fr.) Pers. 10 parts, Herba Hedyotidis Diffusae 6.5 parts, Testis et Pentis Canis 12 parts, Carnis Pseudosciaenae 27 parts, 11 parts of Radix Glycyrrhizae, Gallus Domesticus 48 parts.
Above-mentioned have the keep healthy preparation method of medicated diet of potentiation and be chemotherapy:
(1) being cleaned by Carnis Pseudosciaenae, gill, fish body is cut sth. askew two cuttves, puts salt applied, pickles 10 hours；
(2) by Gallus Domesticus unhairing and internal organs, wash clean, it is cut into small pieces, puts in boiling water and roll 5 minutes, pick up and drain the water；
(3) Radix Astragali, Rhizoma Polygonati, Rhizoma Chuanxiong, Herba Cirrohopetali Andersonii, Fructus Trichosanthis, Hericium erinaceus (Bull. Ex Fr.) Pers., Herba Hedyotidis Diffusae and Radix Glycyrrhizae are cleaned respectively, tighten in then medicine is loaded gauze bag；
(4) putting in saucepan by step (1) and step (2) gained, add water, amount of water is 3.5 times of Carnis Pseudosciaenae and Gallus Domesticus gross weight, step (3) gained medicated bag is put in big fire after boiling, beat offscum after boiling, put into refined salt, monosodium glutamate, onion parts, add a cover and change low baking temperature pot 28 minutes；
(5) Testis et Pentis Canis is cleaned section, tighten in Rhizoma Dioscoreae is loaded gauze bag, put into together with Semen Coicis in above-mentioned pot, add a cover continuation pot 55 minutes, pick medicated bag, to obtain final product.
Model case two:XXX, female, 62 years old.Occur the year before having a stomach-ache, acid regurgitation, the symptom such as defecate irregular, starting her thinks it is that old gastropathy is violated, and oneself is in and has taken some stomach medicines relieved the pain, but effect is undesirable.Checking to local hospital, diagnostic result is gastric cancer comprehensively.Carry out chemotherapy, symptom and the performances such as after chemotherapy, appearance is dizzy, fatigue and weak, lethargy, inappetence, insomnia and dreamful sleep, xerostomia, defecation imbalance.Using the present invention to have the health care medicated diet of potentiation to chemotherapy, food meat is eaten soup, every day twice.After edible 10 days, above-mentioned symptom has taken a turn for the better.After edible 20 days, above-mentioned symptom disappears substantially.After 1 month, carrying out chemotherapy, chemotherapy smoothly completes, and does not has any untoward reaction when chemotherapy.Checking after 2 months, her gastric cancer has obtained effective control, and health constantly recovers.
Embodiment 4Have the health care medicated diet of potentiation to chemotherapy, the primary raw material medicine taking following weight parts is prepared from (every part is 20g): the Radix Astragali 22 parts, Semen Coicis 18 parts, Rhizoma Dioscoreae 17 parts, Rhizoma Polygonati 13 parts, Rhizoma Chuanxiong 14 parts, Herba Cirrohopetali Andersonii 11 parts, Fructus Trichosanthis 12 parts, Hericium erinaceus (Bull. Ex Fr.) Pers. 13 parts, Herba Hedyotidis Diffusae 8 parts, Testis et Pentis Canis 14 parts, Carnis Pseudosciaenae 32 parts, 14 parts of Radix Glycyrrhizae, Gallus Domesticus 56 parts.
Above-mentioned have the keep healthy preparation method of medicated diet of potentiation and be chemotherapy:
(1) being cleaned by Carnis Pseudosciaenae, gill, fish body is cut sth. askew two cuttves, puts salt applied, pickles 14 hours；
(2) by Gallus Domesticus unhairing and internal organs, wash clean, it is cut into small pieces, puts in boiling water and roll 9 minutes, pick up and drain the water；
(3) Radix Astragali, Rhizoma Polygonati, Rhizoma Chuanxiong, Herba Cirrohopetali Andersonii, Fructus Trichosanthis, Hericium erinaceus (Bull. Ex Fr.) Pers., Herba Hedyotidis Diffusae and Radix Glycyrrhizae are cleaned respectively, tighten in then medicine is loaded gauze bag；
(4) putting in saucepan by step (1) and step (2) gained, add water, amount of water is 4 times of Carnis Pseudosciaenae and Gallus Domesticus gross weight, step (3) gained medicated bag is put in big fire after boiling, beat offscum after boiling, put into refined salt, monosodium glutamate, onion parts, add a cover and change low baking temperature pot 35 minutes；
(5) Testis et Pentis Canis is cleaned section, tighten in Rhizoma Dioscoreae is loaded gauze bag, put into together with Semen Coicis in above-mentioned pot, add a cover continuation pot 65 minutes, pick medicated bag, to obtain final product.
Model case three:XXX, female, 62 years old.Main suit: more than diagnosing acute Lymphocytic leukemia ALL2 in August, 1, the 8th chemotherapy.This patient retrieval section after the 5th course for the treatment of chemotherapy is alleviated, and escalated dose thereafter applies import chemotherapeutic, but still can not complete incidence graph.After 8th chemotherapy, heavier side reaction and fever rambunctious, agranulocytosis occur.Using the present invention to have the health care medicated diet of potentiation to chemotherapy, food meat is eaten soup, every day twice.Edible 2 weeks, its spirit, feed recovered as usual, the involved and abstruse smoothness that is able to of defecating, and antibiotic hormone fever in nearly January rambunctious is thoroughly controlled, and hemogram is obviously improved improvement.Edible 1 month, having a blood test as, liver function is all normal, bone marrow smear is complete lasting remission, and patient is without any discomfort.After 1 first quarter moon, again carrying out chemotherapy, chemotherapy smoothly completes, and patient is normal without the most serious chemotherapy side effect, hemogram and life indication.Checking after 3 months that prompting Morbidity control is good, long-term observation is in good health.
Embodiment 5Have the health care medicated diet of potentiation to chemotherapy, the primary raw material medicine taking following weight parts is prepared from (every part is 20g): the Radix Astragali 19 parts, Semen Coicis 17 parts, Rhizoma Dioscoreae 15 parts, Rhizoma Polygonati 12 parts, Rhizoma Chuanxiong 12 parts, Herba Cirrohopetali Andersonii 10 parts, Fructus Trichosanthis 10 parts, Hericium erinaceus (Bull. Ex Fr.) Pers. 11 parts, Herba Hedyotidis Diffusae 7 parts, Testis et Pentis Canis 12.5 parts, Carnis Pseudosciaenae 29 parts, 13 parts of Radix Glycyrrhizae, Gallus Domesticus 52 parts.
Above-mentioned have the keep healthy preparation method of medicated diet of potentiation and be chemotherapy:
(1) being cleaned by Carnis Pseudosciaenae, gill, fish body is cut sth. askew two cuttves, puts salt applied, pickles 12 hours；
(2) by Gallus Domesticus unhairing and internal organs, wash clean, it is cut into small pieces, puts in boiling water and roll 7 minutes, pick up and drain the water；
(3) Radix Astragali, Rhizoma Polygonati, Rhizoma Chuanxiong, Herba Cirrohopetali Andersonii, Fructus Trichosanthis, Hericium erinaceus (Bull. Ex Fr.) Pers., Herba Hedyotidis Diffusae and Radix Glycyrrhizae are cleaned respectively, tighten in then medicine is loaded gauze bag；
(4) putting in saucepan by step (1) and step (2) gained, add water, amount of water is 3.8 times of Carnis Pseudosciaenae and Gallus Domesticus gross weight, step (3) gained medicated bag is put in big fire after boiling, beat offscum after boiling, put into refined salt, monosodium glutamate, onion parts, add a cover and change low baking temperature pot 32 minutes；
(5) Testis et Pentis Canis is cleaned section, tighten in Rhizoma Dioscoreae is loaded gauze bag, put into together with Semen Coicis in above-mentioned pot, add a cover continuation pot 60 minutes, pick medicated bag, to obtain final product.
Test exampleGained of the present invention has a clinical practice of the health care medicated diet (embodiment 5) of potentiation to chemotherapy: in April, 2009 in December ,-2012,212 example Patients with Middle-late Malignant Tumors are screened in 9 hospitals, and have visible focus through proved by pathology, make a definite diagnosis rear and accept chemotherapy in hospital, KPS marks more than 60 points, more than March life cycle, every Index for examination meets chemotherapy indication.Wherein male 118 example, women 94 example, oldest 74 years old, minimum 28 years old of age, 59 years old mean age.Diagnosing tumor standard and by stages see " the China's common cancer diagnosis and treatment specification " that Ministry of Health of the People's Republic of China issues.Exclusion standard: 1. do not meet above-mentioned standard；2. psychotic；3. allergic constitution or to multi-medicament allergy sufferers.Being randomly divided into two groups, treatment group and matched group (often organizing 106 people), treatment group uses products obtained therefrom combined with chemotherapy of the present invention, matched group chemotherapy.Treatment group begins to use the health care medicated diet that gained of the present invention has potentiation to chemotherapy for 1 week before chemotherapy, using method: food meat is eaten soup, and every day twice, 1 month is 1 course for the treatment of, shares two courses for the treatment of.
Curative effect is observed: the leading indicator of potentiation: tumor body changes；The secondary index of potentiation: symptom improves situation, animation evaluation (Ka Shi scoring), tumor index of correlation changes, the heart, liver, kidney and hemopoietic system inspection.Efficacy determination: (1) is divided into according to the criterion of WHO tumor efficiency: 1. complete incidence graph (CR): cases of complete remission, continues more than 4 weeks.2. part alleviates (PR): tumor regression more than 50%, continues more than 4 weeks, occurs without new pathological changes.3. stable (NC): tumor regression less than 50% or increase, within 25%, continue more than 4 weeks, occur without new pathological changes.4. (PD) is deteriorated: tumor increases more than 25%, or has new pathological changes (note: tumor size is with the product representation of two mutually perpendicular diameters of maximum) occur.Effectively include that complete incidence graph and part are alleviated.Degree comparative result is alleviated as shown in table 1 after two groups of treatments.(2) Ka Shi scoring (KPS): be chosen as reduction, stable, raising three grades.Treating and terminate to mark front and each course for the treatment of, after terminating all courses for the treatment of, before relatively treatment, >=10 points of persons of scoring increase are " improve and improve ", and scoring >=10 points of persons of minimizing are " reduction ", and≤10 points of persons of increase and decrease that mark are " stablizing ".Effectively include improving and stable.Two groups for the treatment of Life For The Residents of Three Gorges Reservoir Before evaluation (KPS) result of variations are as shown in table 2.
Alleviate degree after the group treatment of 1 liang of table to compare
As can be seen from Table 1, treatment group clinical effective rate is
73.58%, matched group is 31.13%, and treatment group effective percentage is apparently higher than matched group, and difference has significance (P ＜ 0.05).
2 liang of table group treatment Life For The Residents of Three Gorges Reservoir Before evaluation (KPS) change
From table 2, treatment group KPS scoring effective percentage is 97.17%, and matched group is 64.15%.Two groups are compared, and treatment group is substantially better than matched group (P ＜ 0.05).
The present invention, with the Radix Astragali, Semen Coicis, Rhizoma Dioscoreae and Rhizoma Polygonati etc. as primary raw material, makes the health care medicated diet to chemotherapy with potentiation.Radix Astragali invigorating QI to consolidate the body surface resistance in side, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Semen Coicis clearing away heat-damp and promoting diuresis, except rheumatism, diuresis, lung benefiting evacuation of pus, strengthening the spleen and stomach, bone and muscle strengthening.Rhizoma Dioscoreae spleen reinforcing nourishing the stomach, promote the production of body fluid lung benefiting, the kidney invigorating arresting seminal emission.Rhizoma Polygonati nourishing YIN and moistening the lung, invigorating the spleen and replenishing QI, Zishen fill fine.Rhizoma Chuanxiong blood-activating and qi-promoting, wind-expelling pain-stopping.Herba Cirrohopetali Andersonii expelling wind and removing dampness, invigorates blood circulation, cough-relieving, helps digestion long-pending.Fructus Trichosanthis removing heat-phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens, moisturize laxation.Hericium erinaceus (Bull. Ex Fr.) Pers. circulation of qi promoting helps digestion, spleen benefiting and stimulating the appetite, Fructus Alpiniae Oxyphyllae of calming the nerves.Herba Hedyotidis Diffusae heat clearing away, dampness removing, removing toxic substances.Testis et Pentis Canis the kidney invigorating warming YANG.Carnis Pseudosciaenae QI invigorating nourishing the stomach, the kidney invigorating, improving eyesight.Radix Glycyrrhizae invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Gallus Domesticus invigorating the liver and kidney, replenishing QI and blood, reducing the asthenic fever.All medicines share, and have the effects such as invigorating QI to consolidate the body surface resistance, spleen reinforcing nourishing the stomach, nourishing YIN and moistening the lung, blood-activating and qi-promoting, heat-clearing and toxic substances removing, invigorating the liver and kidney, replenishing QI and blood, facilitation protected to body's immunity, enhance ability of self contending with, thus reach to make chemotherapeutic sensitivity purpose.
Finally it should be noted that, embodiment is the detailed description of the invention that the present invention is optimum, it is not limited to the present invention, although the present invention being described in detail with reference to previous embodiment, for a person skilled in the art, technical scheme described in foregoing embodiments still can be modified by it, or wherein portion of techniques feature is carried out equivalent.All within the spirit and principles in the present invention, any modification, equivalent substitution and improvement etc. made, should be included within the scope of the present invention.
Claims (1)
1. there is potentiation to chemotherapy keep healthy the preparation method of medicated diet, it is characterised in that take the crude drug of following portions by weight: the Radix Astragali 19, Semen Coicis 17, Rhizoma Dioscoreae 15, Rhizoma Polygonati 12, Rhizoma Chuanxiong 12, Herba Cirrohopetali Andersonii 10, Fructus Trichosanthis 10, Hericium erinaceus (Bull. Ex Fr.) Pers. 11, Herba Hedyotidis Diffusae 7, Testis et Pentis Canis 12.5, Carnis Pseudosciaenae 29, Radix Glycyrrhizae 13, Gallus Domesticus 52；Step is as follows:
(1) being cleaned by Carnis Pseudosciaenae, gill, fish body is cut sth. askew two cuttves, puts salt applied, pickles 12 hours；
(2) by Gallus Domesticus unhairing and internal organs, wash clean, it is cut into small pieces, puts in boiling water and roll 7 minutes, pick up and drain the water；
(3) Radix Astragali, Rhizoma Polygonati, Rhizoma Chuanxiong, Herba Cirrohopetali Andersonii, Fructus Trichosanthis, Hericium erinaceus (Bull. Ex Fr.) Pers., Herba Hedyotidis Diffusae and Radix Glycyrrhizae are cleaned respectively, tighten in then medicine is loaded gauze bag；
(4) putting in saucepan by step (1) and step (2) gained, add water, amount of water is 3.8 times of Carnis Pseudosciaenae and Gallus Domesticus gross weight, step (3) gained medicated bag is put in big fire after boiling, beat offscum after boiling, put into refined salt, monosodium glutamate, onion parts, add a cover and change low baking temperature pot 32 minutes；
(5) Testis et Pentis Canis is cleaned section, tighten in Rhizoma Dioscoreae is loaded gauze bag, put into together with Semen Coicis in above-mentioned pot, add a cover continuation pot 60 minutes, pick medicated bag, to obtain final product.
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