CN105943566A - Preparation method for compound preparation of water-soluble silicon and traditional Chinese medicinal material or edible material extract - Google Patents
Preparation method for compound preparation of water-soluble silicon and traditional Chinese medicinal material or edible material extract Download PDFInfo
- Publication number
- CN105943566A CN105943566A CN201610251038.5A CN201610251038A CN105943566A CN 105943566 A CN105943566 A CN 105943566A CN 201610251038 A CN201610251038 A CN 201610251038A CN 105943566 A CN105943566 A CN 105943566A
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- Prior art keywords
- water
- extract
- concentration
- food materials
- soluble silicon
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- 229910052710 silicon Inorganic materials 0.000 title claims abstract description 79
- 239000010703 silicon Substances 0.000 title claims abstract description 79
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- 238000002360 preparation method Methods 0.000 title claims abstract description 55
- 150000001875 compounds Chemical class 0.000 title claims abstract description 28
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 138
- 239000002904 solvent Substances 0.000 claims abstract description 87
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 claims abstract description 78
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- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 claims description 20
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims description 18
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- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims description 6
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- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 claims description 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 2
- 239000001569 carbon dioxide Substances 0.000 claims description 2
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Classifications
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Landscapes
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- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention specifically relates to a preparation method for a compound preparation of water-soluble silicon and traditional Chinese medicinal material or edible material extract, belonging to the technical field of food and medicine. The preparation method comprises the following steps: (1) selecting raw materials for subsequent usage; (2) taking raw materials in proportion and preparing a high-concentration water-soluble silicon melt; (3) subjecting the high-concentration water-soluble silicon melt to water quenching and cooling so as to obtain a solid particle; (4) preparing an active water-soluble silicon solution from the solid particle; (5) preparing hyperconcentrated mother liquor from the active water-soluble silicon solution; (6) blending the hyperconcentrated mother liquor and purified water so as to obtain a high-concentration solvent containing active water-soluble silicon; (7) preparing traditional Chinese medicinal material or edible material extract mixed liquor; (8) preparing filtered mixed liquor; (9) preparing mixed liquor with a specific concentration; and (10) sterilizing the mixed liquor. According to the invention, artificial active water-soluble silicon and the traditional Chinese medicinal material or edible material extract are compounded to form the compound preparation and exert synergistic effect, so the compound preparation can improve the growth environment of cells, enhance human immunity and elevate the whole health level of the body.
Description
Technical field:
The invention belongs to food pharmaceutical technology field, refer in particular to a kind of water-soluble silicon and Chinese crude drug or food materials extract
The preparation method of compound preparation.
Background technology:
The health of current people is by empty gas and water, soil and the serious threat of food pollution, thus it is speculated that not
Coming 10 years, China will appear from chronic disease and the phenomenon of tumor and cancer blowout, for curing these fearful diseases,
A lot of family of China will exhaust savings, entire society and country and all will pay heavy cost.
Modern is more because addiction is immoderate, and work and rest is disorderly, and dietetic nutrition is the most scarce, senility of humanbody etc. reason,
Water circulating running system in human body can be destroyed, it can be common that blocking, then can amass poison, become sour, then
Also have and pollute.
Dredge water circulation health in self human body to run, promote cell to nutrient substance, the absorption of functional mass,
Discharge junk, dirt toxin, prevent and improve the three-hypers of modern's doubt, cardiovascular and cerebrovascular disease, sugar
Urine disease, tumor and cancer, osteoporosis, skin allergy, growth retardation, hypoimmunity etc. water route
The chronic disease that infiltration blocking is relevant, is the task of top priority！In current environmental pollution, water resource is exhausted, people
Occurred frequently current of chronic disease, improves self internal water circulation health and runs and be particularly important with urgent.
Human body 60-70% is water, and water participates in internal metabolism, the conveying medium of all materials the most internal.Water circulation bag
Include the running of aqueous water and vapourous water, water channel and air flue combination and could form water circulation health fortune in human body
The complete path of row.Activated silica is the composition foundation stone of human body cell membrane structure, is the base stock repaiied and link up canal,
It it is the material base of the unobstructed transport of aqueous water.Peripheral four Electronic Keyings of activated silica fully open, it is possible to by electricity
The hinged corresponding aminoacid of sub-key covalency and polysaccharide macro-molecular form various functional fibre, fiber architecture connective group
The space multistory framework knitted, such as bone gelatin, annulus fibrosus disci intervertebralis, ligament muscle key, vessel wall elasticity fiber,
Cell membrane fiber etc., needs the nutrition such as various enzyme, aminoacid, saccharide, mineral, vitamin during this
Element is participated.Chinese crude drug and food materials abundant species, the required nutrition that can not synthesize containing many human bodies self
Element.The present invention is the preparation that associating activated silica and Chinese crude drug and food materials extract coordinate making, and said preparation is permissible
In promotion human body, water-borne transport passage is unimpeded, supplements the basal nutrient element that biological cell is required, it is possible to for
Life and health escorts.
Summary of the invention:
It is an object of the invention to provide one and improve cell growing environment, increase body immunity, improve human body
The preparation work containing water-soluble silicon and the compound preparation of Chinese crude drug or food materials extracting solution of overall health level
Skill.
The present invention is achieved in that
Water-soluble silicon and Chinese crude drug or the preparation method of the compound preparation of food materials extract, comprise the steps:
(1) select materials: according to country food grade standard, choose purity more than 90% SiO 2 powder,
The purity sodium carbonate more than 99% or sodium bicarbonate or sodium oxide powder, Chinese medicinal material extract or food materials extract or
Chinese crude drug or food materials, pure water are standby；
(2) high-concentration water-soluble melted silicon is prepared: according to SiO 2 powder, powdered sodium carbonate or bicarbonate
The parts by weight of sodium or sodium oxide powder are (1-4): the proportioning of 1 is selected materials, and put into and add in heat container through 1000 DEG C
-2000 DEG C of high-temperature fusion 8-10 hour are transformed；
(3) solid particle is prepared: use one of following method:
1. high-concentration water-soluble melted silicon prepared by step (2) is obtained solid particle through water quenching cooling；
2. high-concentration water-soluble melted silicon prepared by step (2) is first cooled to 60-600 DEG C, then through water
Quenching but obtains solid particle；
(4) active water soluble silicon solution is prepared: solid particle prepared by step (3) is placed in reaction vessel
In be heated to 150 DEG C 180 DEG C, be forced into 1-6 atmospheric pressure after, add pure water and stir, grind, dissolve
Obtain active water soluble silicon solution；
(5) ultra concentration mother solution is prepared: active water soluble silicon solution step (4) obtained adds pure water will
Silicon concentration is diluted to 8400ppm-25000ppm, as ultra concentration mother solution；
(6) solvent containing active water soluble silicon of high concentration is allocated: take the ultra concentration that step (5) makes
Mother solution adds pure water and is deployed into the active water soluble siloxane solvent of high concentration, high concentration active water soluble siloxane solvent
Concentration is 100-8400ppm；
(7) mixed liquor is made: use one of following two kinds of methods:
1. Chinese medicinal material extract or food materials extract is selected to make:
The active water soluble siloxane solvent of high concentration step (6) allocated extracts with Chinese medicinal material extract or food materials
Thing is 100:(0.01-50 according to ratio of weight and number) ratio be mixed to get mixed liquor；
2. Chinese crude drug or food materials are selected to make:
A, making powdery Chinese medicine or powdery food materials: take Chinese crude drug or food materials, dry, pulverize, sieve, do
Dry, obtain powdery Chinese medicine or the powdery food materials of 60-100 mesh；
B, by the powdery Chinese medicine in A or powdery food materials, take (0.3-1500g), add high concentration at twice
Active water soluble siloxane solvent, each 480 ± 20ml, at constant temperature at 58 62 DEG C, utilize extracting solution to extract
Method is extracted 28-32 minute, front and back merges the Chinese crude drug mixed liquor obtained for twice or food materials mixed liquor, and it is dense
Degree is equivalent to (the 0.03-150g)/100ml of Chinese crude drug or food materials；
(8) mixed liquor in step (7) is sufficiently stirred for, cooling, then 3-5 DEG C of cold preservation 0.5-5 hour
After, centrifugal filtration, obtain filtrate set aside for use；
(9) in the filtrate obtained in step (8) add pure water or/and step (5) make super dense
Contracting mother solution to total amount is 1000ml ± 50ml and controls the concentration of water-soluble silicon at 8400 ± 100ppm；Stir again
Mix, 3-5 DEG C of cold preservation, filter, remove particulate contaminant and obtain filtrate set aside for use；
(10) sterilization: the solution obtained in step (9) is sterilized.
In the preparation method of above-mentioned water-soluble silicon and the compound preparation of Chinese crude drug or food materials extract, step
(7) extracting solution extracting method described in is: ultrasonic extraction or Hot water extraction or alcohol alkali method or send out
Ferment extraction method or supercritical extraction or Multifunction hand are followed the example of or dynamically continuous overflow extracts.
At above-mentioned water-soluble silicon with the preparation method of Chinese crude drug or the compound preparation of food materials extract, also wrap
Include following steps:
(11) continue the solution obtained in step (9) to add pure water or add that step (5) makes super
Concentrated mother liquor obtains the water-soluble silicon solution that silicon concentration is 1-8400ppm；
(12) sterilization: the water-soluble silicon solution obtained in step (11) is sterilized.
In the preparation method of above-mentioned water-soluble silicon and the compound preparation of Chinese crude drug or food materials extract, described
Sterilization in step (10), (11) uses stainless steel pipes ultraviolet sterilization or boils sterilization.
At above-mentioned water-soluble silicon with the preparation method of Chinese crude drug or the compound preparation of food materials extract, also wrap
Include following steps:
(13) solution after step (10) or step (12) being sterilized is set by fill under gnotobasis
Standby fill；
(14) the product-filled labeling that step (13) is obtained；
(15) vanning: by step (14) labeling packaging products in boxes；
(16) storage: the product after step (15) being cased is put cool place, is dried, stores at lucifuge.
In the preparation method of above-mentioned water-soluble silicon and the compound preparation of Chinese crude drug or food materials extract, described
Water-soluble silicon concentration is in the case of 8400ppm, and needed for every 100ml active water soluble siloxane solvent, Chinese crude drug extracts
The usage amount of thing or food materials extract is one of following ingredients and content:
Ganoderma extract: 6 ± 0.5g/100ml；
Semen Ginkgo or Folium Ginkgo extract: 6 ± 0.5g/100ml；
Radix Notoginseng, Radix Salviae Miltiorrhizae extract: (10 ± 0.5g:10 ± 0.5g)/100ml；
Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong extract: (10 ± 0.5g:30 ± 2g)/100ml；
Radix Notoginseng, Rhizoma Gastrodiae extract: (10 ± 0.5g:30 ± 2g)/100ml；
Astragalus polysaccharides: 30 ± 2g/100ml；
Wolfberry fruit extract: 30 ± 2g/100ml；
Radix Salviae Miltiorrhizae extract: 10 ± 0.5g/100ml；
Cacumen Platycladi (Cacumen Biotae) quintessence oil: 10 ± 0.5ml/100ml；
Collagen protein: 30 ± 2g/100ml；
Aminoacid: 30g ± 2/100ml；
Hyaluronic acid: 5g ± 0.25/100ml；
Radix Ginseng extract: 5 ± 0.5g/100ml.
In the preparation method of above-mentioned water-soluble silicon and the compound preparation of Chinese crude drug or food materials extract, described
Water-soluble silicon concentration in the case of 8400ppm, Chinese crude drug or food needed for every 100ml active water soluble siloxane solvent
The usage amount of material is one of following ingredients and content:
Ganoderma: 30 ± 1.5g/100ml；
Semen Ginkgo or Folium Ginkgo: 30 ± 1.5g/100ml；
Radix Notoginseng, Radix Salviae Miltiorrhizae: (50 ± 2.5g:50 ± 2.5g)/100ml；
Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong: (50 ± 2.5g:150 ± 7.5g)/100ml；
Radix Notoginseng, Rhizoma Gastrodiae: (50 ± 2.5g:150 ± 7.5g)/100ml；
The Radix Astragali: 150 ± 7.5g/100ml；
Fructus Lycii: 150 ± 7.5g/100ml；
Radix Salviae Miltiorrhizae: 50 ± 2.5g/100ml；
Radix Ginseng: 25 ± 1.3g/100ml.
In the preparation method of above-mentioned water-soluble silicon and the compound preparation of Chinese crude drug or food materials extract, described
Compound preparation prepare in the environment of relative insulation carbon dioxide.
The advantage that the present invention highlights compared to existing technology is:
1, the present invention artificial active water soluble silicon derives from the silicate of high-quality particular modulus (1-4), silicon
Hydrochlorate is commonly used to industrial circle, and particular modulus silicate is selected to optimize by further, it is used for
Food and medicine field, Combined with Chinese Herbal material and food materials extracting solution are made special dietary solution and are supplemented organism and must seek
Support the shortage of element.
2, the artificial active water soluble silicon of the present invention and Chinese crude drug or the compound preparation of food materials extracting solution, both associations
Same-action, improves cell growing environment, increases body immunity, improves the health level that human body is overall.
3, present invention active water soluble siloxane solvent makees Extraction medium, the Chinese crude drug that more can effectively extract or food materials
Effective ingredient, active water soluble silicon have efficient permeability and decompose emulsifying capacity, can be by some lipids
Insoluble effective ingredient is decomposed into water soluble ingredient, is more conducive to transported in human body utilization.
4, the activated silica in the active water soluble silicon pharmaceutical solutions of high concentration of the present invention can dilute hydrolysis and excites and release
Putting hydrion, in human body, reproducibility hydrion has selectivity non-oxidizability, can be harmful to certainly by competition binding
By base, dredge silting；Activated silica framework space, builds path, assists infiltration；Chinese crude drug or food materials provide
Nutrition, combines efficiently, improves the nutrient environment of cell comprehensively, improves cellular immunity, promotes human body whole
Body health vigor.
Detailed description of the invention:
With specific embodiment, the invention will be further described below:
Embodiment one:
The present embodiment is chosen Ganoderma extract and is carried out the preparation of water-soluble silicon and the compound preparation of Ganoderma extract.
Water-soluble silicon and Chinese crude drug or the preparation method of the compound preparation of food materials extract, at relative insulation dioxy
Carrying out in the environment of changing carbon, substantial length of operation selects to carry out in hermetic container or pipeline, reduces with empty as far as possible
The contact of gas, comprises the steps:
(1) select materials: according to the food grade standard of country, choose: 1, the purity silicon dioxide powder more than 90%
End, purity more than 99% powdered sodium carbonate or sodium bicarbonate powder or sodium oxide powder, 2, take Ganoderma extract
60g or raw material Ganoderma 300g, 3, pure water standby.
Various data show that the pharmacological action of Ganoderma lucidum (Leyss. Ex Fr.) Karst. is substantially superior to other lucidum variety, and effective one-tenth of 85%
Dividing and concentrate on cap, therefore this case uses Ganoderma lucidum (Leyss. Ex Fr.) Karst. extracting solution.
(2) high-concentration water-soluble melted silicon is prepared: according to the SiO 2 powders of 2.5 parts, 1 part of sodium carbonate powder
The ratio of end or sodium bicarbonate powder or sodium oxide powder carries out proportioning, and puts in electric kiln or gas kiln
It is transformed through 1000 DEG C of-2000 DEG C of high-temperature fusion 8-10 hour.Temperature and melting time are according to practical situation
Any value within the above range.
(3) solid particle is prepared: use one of following method:
1. high-concentration water-soluble melted silicon prepared by step (2) is obtained solid particle through water quenching cooling；
2. high-concentration water-soluble melted silicon prepared by step (2) is first cooled to 60-600 DEG C, then through shrend
Cooling obtains solid particle；When using this step, the chilling temperature of high-concentration water-soluble melted silicon can be upper
In the range of stating, any value, is typically based on practical situation and selects.
(4) active water soluble silicon solution is prepared: the solid particle of preparation in step (3) is placed in reaction vessel
In be heated to 150 DEG C 180 DEG C, pressurization 1-6 atmospheric pressure after, add pure water and stir, grind, dissolve
To active water soluble silicon solution.The temperature of reaction vessel and pressure are according to practical situation value within the above range.
(5) ultra concentration mother solution is prepared: active water soluble silicon solution step (4) obtained adds pure water,
Silicon concentration is diluted to 8400-25000ppm, as ultra concentration mother solution.
(6) the active water soluble siloxane solvent of high concentration is allocated: take the ultra concentration mother solution that step (5) makes and add
Pure water is deployed into the active water soluble siloxane solvent of high concentration, and the concentration of active water soluble siloxane solvent is according to reality
Produce needs to control at 100-8400ppm.Under room temperature, pure water dilution can be added and be deployed into the activity of variable concentrations
Water-soluble silicon solvent.
(7) mixed liquor is made: use one of following two kinds of methods:
One is directly to select Ganoderma extract to make:
The active water soluble siloxane solvent of the high concentration allocated according to step (6) and Ganodernaa lucidum extract are with reference to weight
Portion rate is 100:(0.01-50) ratio be mixed to get mixed liquor.Active water soluble siloxane solvent carries with Ganoderma lucidum (Leyss. Ex Fr.) Karst.
The weight fraction ratio taking thing can any value within the above range.
The present embodiment when the concentration of active water soluble siloxane solvent is 8400ppm, the active water soluble of 100ml
Siloxane solvent selects the Ganodernaa lucidum extract of 6g.Different according to concentration, the weight of the regulation Ganodernaa lucidum extract of equal proportion,
As: when concentration is 4200ppm, the active water soluble siloxane solvent of 100ml selects the Ganodernaa lucidum extract of 3g, with
Secondary analogize.
Another kind is to select Ganoderma to make:
A, making ganoderma lucidum powder: take Ganoderma lucidum (Leyss. Ex Fr.) Karst., dry, pulverize, sieve, be dried, obtain 60-100 purpose
Ganoderma lucidum powder；
B, by the ganoderma lucidum powder in A, take 300g, at twice add high concentration active water soluble siloxane solvent, often
Secondary 500ml, constant temperature, at 58 62 DEG C, utilizes extracting solution extracting method to extract 28-32 minute, front and back merges
The ganoderma lucidum powder extracting solution obtained for twice, obtains concentration and is equivalent to the Ganoderma of Ganoderma former mycopowder 30g/100ml and carries
Take liquid (concentration of active water soluble siloxane solvent is 8400ppm).Different according to concentration, the regulation spirit of equal proportion
Sesame weight, such as: when concentration is 4200ppm, the active water soluble siloxane solvent of 100ml selects the Ganoderma lucidum (Leyss. Ex Fr.) Karst. of 15g,
Analogize with secondary.
Described extracting solution extracting method is: ultrasonic extraction or Hot water extraction or alcohol alkali method or fermentation
Extraction method or supercritical extraction or Multifunction hand are followed the example of or dynamically continuous overflow extracts.
(8) being sufficiently stirred for by the mixed liquor obtained in step (7), cooling, 3-5 DEG C DEG C of cold preservation 0.5-5 is little
Time, centrifugal filtering, obtain filtrate set aside for use.Refrigerated storage temperature and time according to practical situation in above-mentioned scope
Interior arbitrarily value.
(9) filtrate step (8) obtained adds pure water or/and the ultra concentration that makes of step (5) is female
Liquid to total amount is 1000ml, it is allowed to there are error.And control the concentration of water-soluble silicon 8400ppm ±
100ppm；Being stirred for, 3-5 DEG C of cold preservation, or cloth cotton by (1-5umPP) filters, and removes particulate contaminant and obtains
To filtrate set aside for use.By mode detectable concentrations such as ICP atom luminescence analysis or atom extinction brightness methods,
Refrigerated storage temperature and time are according to practical situation any value within the above range.
(10) sterilization: the filtrate obtained in step (9) is sterilized by stainless steel pipes ultraviolet sterilizer,
Obtain solution.
(11) continue the solution obtained in step (9) to add pure water dilution or add that step (5) makes super
Concentrated mother liquor obtains the solution of various water-soluble silicon solution variable concentrations, and concentration is 1-8400ppm；Making
Cheng Zhong, owing to water-soluble silicon has loss, it is therefore desirable to adds pure water or adds ultra concentration mother solution regulation concentration,
Concrete concentration selects according to practical situation.
(12) solution obtained in step (11) is used stainless steel pipes ultraviolet sterilization or boil sterilize into
Row sterilization.
(13) solution after step (10) or (12) being sterilized passes through filling apparatus fill under gnotobasis.
(14) step (13) is obtained product-filled labeling；
(15) vanning: by the labeling packaging products in boxes of step (14).
(16) storage: the finished product after step (15) being cased is put cool place, is dried, stores at lucifuge.
Embodiment two:
The present embodiment is essentially identical with embodiment one, and its difference is: when preparing high-concentration water-soluble silicon solution,
The number ratio of silicon dioxide, powdered sodium carbonate or sodium bicarbonate powder or sodium oxide powder is 3:1, namely
3 parts of silicon dioxide, 1 part of powdered sodium carbonate or sodium bicarbonate powder or sodium oxide powder.
Embodiment three:
The present embodiment is essentially identical with embodiment one, and its difference is: when preparing high-concentration water-soluble silicon solution,
The number ratio of silicon dioxide, powdered sodium carbonate or sodium bicarbonate powder or sodium oxide powder is 3.5:1, the most just
It is 3.5 parts of silicon dioxide, 1 part of powdered sodium carbonate or sodium bicarbonate powder or sodium oxide powder.
Embodiment four: the present embodiment is essentially identical with embodiment one, its difference is: select Semen Ginkgo or Semen Ginkgo
Leaf extract.Semen Ginkgo or Folium Ginkgo extract are to extract from Semen Ginkgo or Folium Ginkgo.Molten at active water soluble silicon
When the concentration of agent is 8400ppm, the active water soluble siloxane solvent of 100ml selects the Semen Ginkgo of 6g or Folium Ginkgo to carry
Take thing.Different according to concentration, the regulation Semen Ginkgo of equal proportion or the weight of Folium Ginkgo extract, such as: concentration is
During 2100ppm, the active water soluble siloxane solvent of 100ml selects Semen Ginkgo or the Folium Ginkgo extract of 1.5g, with
This analogizes.
Embodiment five: the present embodiment is essentially identical with embodiment one, its difference is: select Semen Ginkgo or Semen Ginkgo
Leaf.When the concentration of active water soluble siloxane solvent is 8400ppm, the active water soluble siloxane solvent of 100ml is selected
30g Semen Ginkgo or Folium Ginkgo.Different according to concentration, the regulation Semen Ginkgo of equal proportion or the weight of Folium Ginkgo, such as:
When concentration is 1050ppm, the active water soluble siloxane solvent of 100ml selects 3.75g Semen Ginkgo or Folium Ginkgo, with
This analogizes.
Embodiment six: the present embodiment is essentially identical with embodiment one, its difference is: select Radix Notoginseng, Radix Salviae Miltiorrhizae
Extract.Radix Notoginseng, Radix Salviae Miltiorrhizae extract are extracted according to weight ratio 1:1 by Radix Notoginseng, Radix Salviae Miltiorrhizae.At active water soluble silicon
When the concentration of solvent is 8400ppm, the active water soluble siloxane solvent of 100ml select 10g Radix Notoginseng extract,
The Radix Salviae Miltiorrhizae extract of 10g.Different according to concentration, regulation Radix Notoginseng, the weight of Radix Salviae Miltiorrhizae extract of equal proportion, such as:
When concentration is 8000ppm, the active water soluble siloxane solvent of 100ml select the Radix Notoginseng extract of 9.52g, 9.52
The Radix Salviae Miltiorrhizae extract of g, by that analogy.
Embodiment seven: the present embodiment is essentially identical with embodiment one, its difference is: select Radix Notoginseng, Radix Salviae Miltiorrhizae.
Radix Notoginseng, Radix Salviae Miltiorrhizae weight ratio are 1:1.When the concentration of active water soluble siloxane solvent is 8400ppm, 100ml's
Active water soluble siloxane solvent selects the Radix Notoginseng of 50g, the Radix Salviae Miltiorrhizae of 50g.Different according to concentration, the regulation of equal proportion
Radix Notoginseng, the weight of Radix Salviae Miltiorrhizae, such as: when concentration is 1680ppm, the active water soluble siloxane solvent of 100ml is selected
The Radix Notoginseng of 10g, the Radix Salviae Miltiorrhizae of 10g, by that analogy.
Embodiment eight: the present embodiment is essentially identical with embodiment one, its difference is: select Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong
Extract.Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong extract are extracted according to weight ratio 1:3 by Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong.At active water soluble silicon
When the concentration of solvent is 8400ppm, the active water soluble siloxane solvent of 100ml select 10g Radix Salviae Miltiorrhizae extract,
The Rhizoma Chuanxiong extract of 30g.Different according to concentration, regulation Radix Salviae Miltiorrhizae, the weight of Rhizoma Chuanxiong extract of equal proportion, such as:
When concentration is 7000ppm, the active water soluble siloxane solvent of 100ml selects the Radix Salviae Miltiorrhizae extract of 8.33g, 24.99g
Rhizoma Chuanxiong extract, by that analogy.
Embodiment nine: the present embodiment is essentially identical with embodiment one, its difference is: select Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong.
Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong weight ratio are 1:3.When the concentration of active water soluble siloxane solvent is 8400ppm, 100ml's
Active water soluble siloxane solvent selects the Radix Salviae Miltiorrhizae of 50g, the Rhizoma Chuanxiong of 150g.Different according to concentration, the tune of equal proportion
Joint Radix Salviae Miltiorrhizae, the weight of Rhizoma Chuanxiong, such as: when concentration is 560ppm, the active water soluble siloxane solvent of 100ml is selected
3.33g Radix Salviae Miltiorrhizae, the Rhizoma Chuanxiong of 10g, by that analogy.
Embodiment ten: the present embodiment is essentially identical with embodiment one, its difference is: select Radix Notoginseng, Rhizoma Gastrodiae
Extract.Radix Notoginseng, Rhizoma Gastrodiae extract are extracted according to weight ratio 1:3 by Radix Notoginseng, Rhizoma Gastrodiae.At active water soluble
When the concentration of siloxane solvent is 8400ppm, the active water soluble siloxane solvent of 100ml select 10g Radix Notoginseng extract,
The Rhizoma Gastrodiae extract of 30g.Different according to concentration, regulation Radix Notoginseng, the weight of Rhizoma Gastrodiae extract of equal proportion, such as:
When concentration is 210ppm, the active water soluble siloxane solvent of 100ml selects the Radix Notoginseng extract of 1g, 3g
Rhizoma Gastrodiae extract, by that analogy.
Embodiment 11: the present embodiment is essentially identical with embodiment one, its difference is: select Radix Notoginseng, sky
Fiber crops.Radix Notoginseng, Rhizoma Gastrodiae weight ratio are 1:3.When the concentration of active water soluble siloxane solvent is 8400ppm, 100ml
Active water soluble siloxane solvent select the Radix Notoginseng of 50g, the Rhizoma Gastrodiae of 150g.Different according to concentration, equal proportion
Regulation Radix Notoginseng, the weight of Rhizoma Gastrodiae extract, such as: during 700ppm, the active water soluble siloxane solvent choosing of 100ml
With the Radix Notoginseng of 4.16g, the Rhizoma Gastrodiae of 12.5g, by that analogy.
Embodiment 12: the present embodiment is essentially identical with embodiment one, its difference is: select astragalus polysaccharides.
Astragalus polysaccharides extracts from the Radix Astragali.When the concentration of active water soluble siloxane solvent is 8400ppm, the work of 100ml
Property water-soluble silicon solvent select 30g astragalus polysaccharides.Different according to concentration, the regulation astragalus polysaccharides of equal proportion
Weight, such as: when concentration is 6000ppm, the active water soluble siloxane solvent of 100ml selects 21.42g's
Astragalus polysaccharides, by that analogy.
Embodiment 13: the present embodiment is essentially identical with embodiment one, its difference is: select the Radix Astragali.?
When the concentration of active water soluble siloxane solvent is 8400ppm, the active water soluble siloxane solvent of 100ml selects 150g
The Radix Astragali.Different according to concentration, the weight of the regulation Radix Astragali of equal proportion, such as: when concentration is 560ppm,
The active water soluble siloxane solvent of 100ml selects the Radix Astragali of 10g, by that analogy.
Embodiment 14: the present embodiment is essentially identical with embodiment one, its difference is: select Fructus Lycii to extract
Thing.Wolfberry fruit extract extracts from Fructus Lycii.When the concentration of active water soluble siloxane solvent is 8400ppm, 100ml
Active water soluble siloxane solvent select 30g wolfberry fruit extract.Different according to concentration, the regulation Chinese holly of equal proportion
The weight of Qi extract, such as: when concentration is 5000ppm, the active water soluble siloxane solvent of 100ml selects 17.86g
Wolfberry fruit extract, by that analogy.
Embodiment 15: the present embodiment is essentially identical with embodiment one, its difference is: select Fructus Lycii.?
When the concentration of active water soluble siloxane solvent is 8400ppm, the active water soluble siloxane solvent of 100ml selects 150g
Fructus Lycii.Different according to concentration, the weight of the regulation Fructus Lycii of equal proportion, such as: when concentration is 840ppm,
The active water soluble siloxane solvent of 100ml selects the Fructus Lycii of 15g.
Embodiment 16: the present embodiment is essentially identical with embodiment one, its difference is: select Radix Salviae Miltiorrhizae to extract
Thing, is also TANSHINONES.Radix Salviae Miltiorrhizae extract extracts from Radix Salviae Miltiorrhizae.Concentration at active water soluble siloxane solvent is
During 8400ppm, the active water soluble siloxane solvent of 100ml selects the Radix Salviae Miltiorrhizae extract of 10g.It is different according to concentration,
The weight of the regulation Radix Salviae Miltiorrhizae extract of equal proportion, such as: when concentration is 420ppm, the active water soluble of 100ml
Siloxane solvent selects the Radix Salviae Miltiorrhizae extract of 0.5g, by that analogy.
Embodiment 17: the present embodiment is essentially identical with embodiment one, its difference is: select Radix Salviae Miltiorrhizae.?
When the concentration of active water soluble siloxane solvent is 8400ppm, the active water soluble siloxane solvent of 100ml selects 50g's
Radix Salviae Miltiorrhizae.Different according to concentration, the weight of the regulation Radix Salviae Miltiorrhizae extract of equal proportion, such as: concentration is 1680ppm
Time, the active water soluble siloxane solvent of 100ml selects the Radix Salviae Miltiorrhizae of 10g, by that analogy.
Embodiment 18: the present embodiment is essentially identical with embodiment one, its difference is: select Cacumen Platycladi (Cacumen Biotae) quintessence oil.
Cacumen Platycladi (Cacumen Biotae) quintessence oil extracts from Cacumen Platycladi, juniper leaf.When the concentration of active water soluble siloxane solvent is 8400ppm,
The active water soluble siloxane solvent of 100ml selects the Cacumen Platycladi (Cacumen Biotae) quintessence oil of 10ml.Different according to concentration, the tune of equal proportion
The weight of joint Cacumen Platycladi (Cacumen Biotae) quintessence oil, when being 2100ppm such as concentration, the active water soluble siloxane solvent of 100ml selects 2.5ml
Cacumen Platycladi (Cacumen Biotae) quintessence oil, by that analogy.
Embodiment 19: the present embodiment is essentially identical with embodiment one, its difference is: select collagen protein.
Collagen protein is from fish skin or Corii Sus domestica or Os Sus domestica or the first-class middle extraction of Os Bovis seu Bubali.Dense at active water soluble siloxane solvent
When degree is for 8400ppm, the active water soluble siloxane solvent of 100ml selects the collagen protein of 30g.According to concentration not
With, the weight of the regulation collagen protein of equal proportion, when being 2100ppm such as concentration, the activity of 100ml is water-soluble
Property siloxane solvent select 7.5g collagen protein, by that analogy.
Embodiment 20: the present embodiment is essentially identical with embodiment one, its difference is: select aminoacid.
Aminoacid from vegetable protein (such as: Semen sojae atricolor etc.) or animal proteinum (such as Pupa bombycis or silkworm silk or Medulla sus domestica or Medulla Bovis seu Bubali or
Bone etc.) middle extraction.When the concentration of active water soluble siloxane solvent is 8400ppm, the activity of 100ml is water-soluble
Property siloxane solvent select 30g aminoacid.Different according to concentration, the amino acid whose weight of regulation of equal proportion, as
During concentration 840ppm, the active water soluble siloxane solvent of 100ml selects the aminoacid of 3g, by that analogy.
Embodiment 21: the present embodiment is essentially identical with embodiment one, its difference is: select hyalomitome
Acid.Hyaluronic acid is obtained by saccharine material fermentation.When the concentration of active water soluble siloxane solvent is 8400ppm,
The active water soluble siloxane solvent of 100ml selects the hyaluronic acid of 5g.Different according to concentration, the regulation of equal proportion
The weight of hyaluronic acid, during such as concentration 4200ppm, the active water soluble siloxane solvent of 100ml selects 2.5g
Hyaluronic acid, by that analogy.
Embodiment 22: the present embodiment is essentially identical with embodiment one, its difference is: select Radix Ginseng to carry
Take thing.Radix Ginseng extract is extracted by Radix Ginseng.When the concentration of active water soluble siloxane solvent is 8400ppm, 100ml
Active water soluble siloxane solvent select 5g Radix Ginseng extract.Different according to concentration, the regulation Radix Ginseng of equal proportion
The weight of extract, during such as concentration 4200ppm, the active water soluble siloxane solvent of 100ml selects 2.5g's
Radix Ginseng extract, by that analogy.
Embodiment 23: the present embodiment is essentially identical with embodiment one, its difference is: select Radix Ginseng.
When the concentration of active water soluble siloxane solvent is 8400ppm, the active water soluble siloxane solvent of 100ml selects 25g
Radix Ginseng.Different according to concentration, the weight of the regulation Radix Ginseng extract of equal proportion, if concentration is 336ppm
Time, the active water soluble siloxane solvent of 100ml selects the Radix Ginseng of 1g, by that analogy.
Above-described embodiment is only one of presently preferred embodiments of the present invention, not limits the present invention's with this
Practical range, therefore: the equivalence change that all shapes under this invention, structure, principle are done, all should
Within being covered by protection scope of the present invention.
Claims (8)
1. water-soluble silicon and Chinese crude drug or the preparation method of the compound preparation of food materials extract, it is characterised in that:
Comprise the steps:
(1) select materials: according to country food grade standard, choose purity more than 90% SiO 2 powder,
The purity sodium carbonate more than 99% or sodium bicarbonate or sodium oxide powder, Chinese medicinal material extract or food materials extract or
Chinese crude drug or food materials, pure water are standby；
(2) high-concentration water-soluble melted silicon is prepared: according to SiO 2 powder, powdered sodium carbonate or bicarbonate
The parts by weight of sodium or sodium oxide powder are (1-4): the proportioning of 1 is selected materials, and put into and add in heat container through 1000 DEG C
-2000 DEG C of high-temperature fusion 8-10 hour are transformed；
(3) solid particle is prepared: use one of following method:
1. high-concentration water-soluble melted silicon prepared by step (2) is obtained solid particle through water quenching cooling；
2. high-concentration water-soluble melted silicon prepared by step (2) is first cooled to 60-600 DEG C, then through water
Quenching but obtains solid particle；
(4) active water soluble silicon solution is prepared: solid particle prepared by step (3) is placed in reaction vessel
In be heated to 150 DEG C 180 DEG C, be forced into 1-6 atmospheric pressure after, add pure water and stir, grind, dissolve
Obtain active water soluble silicon solution；
(5) ultra concentration mother solution is prepared: active water soluble silicon solution step (4) obtained adds pure water will
Silicon concentration is diluted to 8400-25000ppm, as ultra concentration mother solution；
(6) the active water soluble siloxane solvent of high concentration is allocated: take the ultra concentration mother solution that step (5) makes and add
Pure water is deployed into the active water soluble siloxane solvent of high concentration, and the concentration of high concentration active water soluble siloxane solvent is
100-8400ppm；
(7) mixed liquor is made: use one of following two kinds of methods:
1. Chinese medicinal material extract or food materials extract is selected to make:
The active water soluble siloxane solvent of high concentration step (6) allocated extracts with Chinese medicinal material extract or food materials
Thing is 100:(0.01-50 according to ratio of weight and number) ratio be mixed to get mixed liquor；
2. Chinese crude drug or food materials are selected to make:
A, making powdery Chinese medicine or powdery food materials: take Chinese crude drug or food materials, dry, pulverize, sieve, do
Dry, obtain powdery Chinese medicine or the powdery food materials of 60-100 mesh；
(8) mixed liquor in step (7) is sufficiently stirred for, cooling, then B, by the powdery Chinese medicine in A
Material or powdery food materials, take (0.3-1500g), adds the active water soluble siloxane solvent of high concentration at twice, often
Secondary 480 ± 20ml, at constant temperature at 58 62 DEG C, utilizes extracting solution extracting method to extract 28-32 minute, front
Chinese crude drug mixed liquor that rear merging obtains for twice or food materials mixed liquor, its concentration is equivalent to Chinese crude drug or food materials
(0.03-150g)/100ml；
After 3-5 DEG C of cold preservation 0.5-5 hour, centrifugal filtration, obtain filtrate set aside for use；
(9) in the filtrate obtained in step (8) add pure water or/and step (5) make super dense
Contracting mother solution to total amount is 1000ml ± 50ml and controls the concentration of water-soluble silicon at 8400ppm ± 100ppm；
It is stirred for, 3-5 DEG C of cold preservation 0.5-5 hour, filters, remove particulate contaminant and obtain filtrate set aside for use；
(10) sterilization: the filtrate obtained in step (9) is sterilized.
Water-soluble silicon the most according to claim 1 and Chinese crude drug or the system of the compound preparation of food materials extract
Preparation Method, it is characterised in that: described in step (7), extracting solution extracting method is: ultrasonic extraction or heat
Water extract method or alcohol alkali method or fermented extracted method or supercritical extraction or Multifunction hand are followed the example of or dynamically connect
Continuous overflow is extracted.
Water-soluble silicon the most according to claim 1 and Chinese crude drug or the system of the compound preparation of food materials extract
Preparation Method, it is characterised in that: also comprise the steps:
(11) continue the solution obtained in step (10) to add pure water or add that step (5) makes super
Concentrated mother liquor obtains the water-soluble silicon solution that silicon concentration is 1-8400ppm；
(12) sterilization: the water-soluble silicon solution obtained in step (11) is sterilized.
Water-soluble silicon the most according to claim 3 and Chinese crude drug or the system of the compound preparation of food materials extract
Preparation Method, it is characterised in that: the sterilization in described step (10), (11) uses stainless steel pipes ultraviolet
Line sterilizes or boils sterilization.
Water-soluble silicon the most according to claim 3 and Chinese crude drug or the system of the compound preparation of food materials extract
Preparation Method, it is characterised in that: also comprise the steps:
(13) solution after step (10) or step (12) being sterilized is set by fill under gnotobasis
Standby fill；
(14) the product-filled labeling that step (13) is obtained；
(15) vanning: by step (14) labeling packaging products in boxes；
(16) storage: the product after step (15) being cased is put cool place, is dried, stores at lucifuge.
Water-soluble silicon the most according to claim 1 and Chinese crude drug or the system of the compound preparation of food materials extract
Preparation Method, it is characterised in that: described water-soluble silicon concentration in the case of 8400ppm, every 100ml activated water
Needed for dissolubility siloxane solvent, the usage amount of Chinese medicinal material extract or food materials extract is one of following ingredients and content:
Ganoderma extract: 6 ± 0.5g/100ml；
Semen Ginkgo or Folium Ginkgo extract: 6 ± 0.5g/100ml；
Radix Notoginseng, Radix Salviae Miltiorrhizae extract: (10 ± 0.5g:10 ± 0.5g)/100ml；
Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong extract: (10 ± 0.5g:30 ± 2g)/100ml；
Radix Notoginseng, Rhizoma Gastrodiae extract: (10 ± 0.5g:30 ± 2g)/100ml；
Astragalus polysaccharides: 30 ± 2g/100ml；
Wolfberry fruit extract: 30 ± 2g/100ml；
Radix Salviae Miltiorrhizae extract: 10 ± 0.5g/100ml；
Cacumen Platycladi (Cacumen Biotae) quintessence oil: 10 ± 0.5ml/100ml；
Collagen protein: 30 ± 2g/100ml；
Aminoacid: 30 ± 2g/100ml；
Hyaluronic acid: 5 ± 0.25g/100ml；
Radix Ginseng extract: 5 ± 0.5g/100ml.
Water-soluble silicon the most according to claim 1 and Chinese crude drug or the system of the compound preparation of food materials extract
Preparation Method, it is characterised in that: described water-soluble silicon concentration in the case of 8400ppm, every 100ml activated water
Needed for dissolubility siloxane solvent, the usage amount of Chinese crude drug or food materials is one of following ingredients and content:
Ganoderma: 30 ± 1.5g/100ml；
Semen Ginkgo or Folium Ginkgo: 30 ± 1.5g/100ml；
Radix Notoginseng, Radix Salviae Miltiorrhizae: (50 ± 2.5g:50 ± 2.5g)/100ml；
Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong: (50 ± 2.5g:150 ± 7.5g)/100ml；
Radix Notoginseng, Rhizoma Gastrodiae: (50 ± 2.5g:150 ± 7.5g)/100ml；
The Radix Astragali: 150 ± 7.5g/100ml；
Fructus Lycii: 150 ± 7.5g/100ml；
Radix Salviae Miltiorrhizae: 50 ± 2.5g/100ml；
Radix Ginseng: 25 ± 1.3g/100ml.
Water-soluble silicon the most according to claim 1 and Chinese crude drug or the system of the compound preparation of food materials extract
Preparation Method, it is characterised in that: described compound preparation is prepared in the environment of relative insulation carbon dioxide.
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| CN107156569A (en) * | 2017-04-05 | 2017-09-15 | 北海市韩能生物科技有限公司 | The drink of containing water-soluble silicon element |
| WO2019074131A1 (en) * | 2017-10-15 | 2019-04-18 | 株式会社パークフォレスト | Antiallergic agent including panax ginseng extract extracted using silicate |
| JP2019193617A (en) * | 2018-05-03 | 2019-11-07 | キム，ドン スル | Manufacturing method of food additive based on silicon |
| CN115778859A (en) * | 2022-12-23 | 2023-03-14 | 李克明 | Skin conditioner |
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