CN105920375A - 一种治疗心脑血管疾病的中药及其制备方法 - Google Patents

一种治疗心脑血管疾病的中药及其制备方法 Download PDF

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CN105920375A
CN105920375A CN201610526334.1A CN201610526334A CN105920375A CN 105920375 A CN105920375 A CN 105920375A CN 201610526334 A CN201610526334 A CN 201610526334A CN 105920375 A CN105920375 A CN 105920375A
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parts
chinese medicine
radix
root
chinese
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贾庭山
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Abstract

本发明属于中药技术领域，尤其涉及一种治疗心脑血管病的中药及其制备方法。一种治疗心脑血管疾病的中药，其特征是：包含按重量份计的以下组分制成：西洋参2‑4份，紫河车1‑3份，紫丹参5‑7份，红景天5‑7份，五味子1‑3份，当归头4‑6份，川芎4‑6份，远志肉3‑5份，水蛭4‑6份，三七4‑6份，炒酸枣仁4‑6份，肉苁蓉7‑9份，雪莲1‑3份，灵芝孢子粉3‑5份，铁皮石斛2‑4份，炙何首乌2‑4份，炙茱萸肉4‑6份，葛根4‑6份，天麻4‑6份，三叶鬼针草9‑11份。诸药相配，相得益彰，共凑益气活血化瘀通经络之功效，广泛用于心脑血管病的治疗。

Description

一种治疗心脑血管疾病的中药及其制备方法
技术领域
本发明属于中药技术领域，尤其涉及一种治疗心脑血管病的中药及其制备方法。
背景技术
目前，心脑血管疾病是一种致残率高的疾病。一旦得上这类疾病，自己很难生活自理，给家庭造成很大的经济负担和心理压力。病人自己也常常因为拖累了家人，心情不畅，反而影响了疾病的治疗。 对于心脑血管疾病，无论是从经济角度、家庭角度，还是从健康角度来讲，唯有预防才是万全之策，高明之举。早一日预防，早一点安心。中治疗心脑血管病的中药方剂，方剂药物在十几味中药原料加工制成，方剂大，配伍量复杂，成本高，产生副作用多，给以患者带来经济负担过重的问题。
发明内容
本发明的目的，是提供一种治疗心脑血管病的中药， 包含按重量份计的以下组分制成：西洋参2-4份，紫河车1-3份，紫丹参5-7份，红景天5-7份，五味子1-3份，当归头4-6份，川芎4-6份，远志肉3-5份，水蛭4-6份，三七4-6份，炒酸枣仁4-6份，肉苁蓉7-9份，雪莲1-3份，灵芝孢子粉3-5份，铁皮石斛2-4份，炙何首乌2-4份，炙茱萸肉4-6份，葛根4-6份，天麻4-6份，三叶鬼针草9-11份。
所述的治疗心脑血管疾病的中药，还包含按重量份计的以下组分制成：降香1-3份，檀香1-3份，炙木耳5-7份，人参2-4份，益智仁2-4份，黄芪9-11份，姜黄4-6份，藏红花4-6份，赤芍1-3份，仙茅2-4份，淫羊藿4-6份，炙双钩藤2-4份，桂皮1-3份，枸杞子3-5份，薤白1-3份，瓜蒌2-4份，砂仁1-3份。
所述的治疗心脑血管疾病的中药：还包含按重量份计的以下组分制成：地龙3-5份，柏子仁3-5份，穿山龙1-3份，石菖蒲1-3份，毛冬青2-4份，决明子2-4份，合欢皮 2-4份，炒山楂片4-6份，地骨皮3-5份，地黄3-5份，郁金2-4份，炙甘草2-4份，鹿茸1-3份，夜交藤3-5份，刺蒺藜2-4份，翻白草1-3份，威灵仁1-3份。
所述的治疗心脑血管疾病的中药，还包含按重量份计的以下组分制成：独活1-3份，桔梗1-3份，全蝎4-6份，泽泻4-6份，冰片1-3份，大枣（无核）1-3份，党参1-3份，莪术2-4份，生龙骨粉2-4份，白芍2-4份，丝瓜络1-3份，乳香或没药2-4份，骨碎补1-3份，番泻叶1-3份，生山药3-5份。
所述的治疗心脑血管疾病的中药：还包含按重量份计的以下组分制成：生赫石3-5份，牡丹皮1-3份，蜈蚣2-4份，知母0.3-0.7份，制附子0.3-0.7份，生大黄0.5-1.5份，芒硝0.3-0.7份，玉米须2-4份，冬瓜皮1-3份，制桑枝1-3份，芡实0.3-0.7份，禹白附0.3-0.7份。
所述的治疗心脑血管疾病的中药：还包含按重量份计的以下组分制成：麦冬2-4份，鸡血藤2-4份，炙桑寄生7-9份，炙杜仲2-3份，锁阳2-3份，柴胡1-3份，补骨脂2-3份，绞股蓝4-6份，狗脊1-2份，制川牛膝3-5份，薏苡仁2-4份，续断1-3份，白术1-3份，桃仁2-4份，陈皮1-3份，熟地黄2-3份，茯苓2-3份，厚朴1-3份，菟丝子2-4份，沙苑子0.5-1.5份，元胡1-3份，瓜萎仁2-4份，黑蚂蚁粉3-5份，墨旱莲2-4份，伸筋草1-3份，木防已1-3份，延胡索2-4份，罗布麻2-4份，徐长卿1-3份，女贞子1-3份，车前子1-3份，葶苈子1-3份，薄荷叶1-3份，南瓜籽2-4份，粉草薢1-3份，黄精4-6份，腊梅花1-3份，白前1-3份，海藻1-3份，蒲公英1-3份，南沙参1-3份，百合2-4份，生牡蛎3-5份，桂枝1-3份，桑叶1-3份，胆南星1-3份，草拔1-3份。
治疗心脑血管疾病的中药，还包含按重量份计的以下组分制成：穿心莲0.3-0.7份，防风0.3-0.7份，黄柏0.3-0.5份，僵蚕0.5-1.5份，栀子0.3-0.7份，茯苓0.3-0.75份，制南星0.3-0.7份，郁金0.3-0.7份，苏木0.3-0.7份，金荞麦1-3份，刘寄奴0.3-0.7份，三棱0.3-0.7份，金竹叶0.5-1.5份，菟丝子0.3-0.7份，沙苑子0.3-0.7份，续断0.3-0.7份，葫芦巴0.3-0.7份，韭子0.3-0.7份，木桶0.3-0.7份。
所述的治疗心脑血管病的中药，所述中药剂型为胶囊剂、粉剂。
一种治疗心脑血管病的中药制备方法，具体步骤为：
（1）按上述重量份进行配料；
（2）将各原料粉碎过70-90目筛，得中药组合物粉剂；将所得中药组合物粉剂按照0.25g/粒剂量按照胶囊剂的加工方法加工成胶囊状剂型。
一种治疗心脑血管病的中药在制备冠心病，心肌梗塞，心绞痛的药物中的应用。
本发明的有益效果是：本发明的药物高达百余种原料制备而成，经提取、微粉化，加工精制而成。其剂型包括胶囊剂、片剂、颗粒剂。诸药相配，相得益彰，共凑益气活血化瘀通经络之功效，用于心脑血管病的治疗，有显著的效果，总有效率达97.73%。
典型病例：
病例1：
张某某，男，63岁，2014年8月在济南第五人民医院做心脏支架手术，术后高血压、冠心病、背胀，伴随阵发性心绞痛，经常失眠，心率不齐，全身无力，不能从事体力劳动。服药5天后睡眠改善，10天后冠心病症明显改善，全身有力，可适当劳动，2月后，冠心病症状全面缓解，血压和血糖正常可控。现在身体状况正常。
病例2：
吕某某，女，62岁，2004年乳腺癌，在山东省肿瘤医院出院后，在济南铁路职工医院查出冠心病、高血压综合症，病史长达10余年，经常失眠，内心烦燥，心率不齐，体弱乏力，气血不足，出大汗。服药3天后睡眠改善，新陈代谢正常，大便通畅，10天左右体质增强，冠心病症明显改善。2月后，冠心病症状全面缓解，血压和血糖正常可控。现在身体状况正常。
病例3：
马某某，男，72岁，2014年以前，先后两次在山东省立医院做心脏支架手术一次（三个支架），心脏搭桥手术一次。冠以病症十分严重，心率不齐，肝肾功能下降。服药5天后睡眠改善，新陈代谢正常，大便通畅，10天左右体质增强，肝肾功能增强，冠心病症明显改善。2月后，冠心病症状全面缓解，血压和血糖正常可控。现在身体状况基本正常。
《根据药物临床试验质量管理规范》和《中药新药临床研究指导原则》，本发明的中药进行了治疗心脑血管病的临床研究。资料与方法：本发明中药组132例，其中男62例，女60例，年龄46-75，平均年龄63岁，病期6个月到10年。以三个周为一个疗程，连用两个疗程，随访3个月。结果发现：本发明中药治疗组132例，临床痊愈105例，显效13例，有效11例，总有效97.73%。结论，本发明中药对心脑血管病有显著疗效。
具体实施方式：
实施例1
一种治疗心脑血管疾病的中药，包含按重量份计的以下组分制成：西洋参3份，紫河车2份，紫丹参6份，红景天6份，五味子2份，当归头5份，川芎5份，远志肉4份，水蛭5份，三七5份，炒酸枣仁5份，肉苁蓉8份，雪莲2份，灵芝孢子粉4份，铁皮石斛3份，炙何首乌3份，炙茱萸肉5份，葛根5份，天麻5份，三叶鬼针草10份。降香2份，檀香2份，炙木耳6份，人参3份，益智仁3份，黄芪10份，姜黄5份，藏红花5份，赤芍2份，仙茅3份，淫羊藿5份，炙双钩藤3份，桂皮2份，枸杞子4份，薤白2份，瓜蒌3份，砂仁2份。地龙4份，柏子仁4份，穿山龙2份，石菖蒲2份，毛冬青3份，决明子3份，合欢皮 3份，炒山楂片5份，地骨皮4份，地黄4份，郁金3份，炙甘草3份，鹿茸2份，夜交藤4份，刺蒺藜3份，翻白草2份，威灵仁2份。独活2份，桔梗2份，全蝎5份，泽泻5份，冰片2份，大枣（无核）2份，党参2份，莪术3份，生龙骨粉3份，白芍3份，丝瓜络2份，乳香或没药3份，骨碎补2份，番泻叶2份，生山药4份。生赫石4份，牡丹皮2份，蜈蚣3份，知母0.5份，制附子0.5份，生大黄1份，芒硝0.5份，玉米须3份，冬瓜皮2份，制桑枝2份，芡实0.5份，禹白附0.5份。
一种治疗心脑血管病的中药制备方法
（1）按上述重量份进行配料；
（2）将各原料粉碎过70-90目筛，得中药组合物粉剂；将所得中药组合物粉剂按照0.25g/粒剂量按照胶囊剂的加工方法加工成胶囊状剂型。
根据该实施例制得的产品对于冠心病（心脏病），心肌梗塞的有效率达到97%。
实施例2
一种治疗心脑血管疾病的中药，包含按重量份计的以下组分制成：西洋参3份，紫河车2份，紫丹参6份，红景天6份，五味子2份，当归头5份，川芎5份，远志肉4份，水蛭5份，三七5份，炒酸枣仁5份，肉苁蓉8份，雪莲2份，灵芝孢子粉4份，铁皮石斛3份，炙何首乌3份，炙茱萸肉5份，葛根5份，天麻5份，三叶鬼针草10份。降香2份，檀香2份，炙木耳6份，人参3份，益智仁3份，黄芪10份，姜黄5份，藏红花5份，赤芍2份，仙茅3份，淫羊藿5份，炙双钩藤3份，桂皮2份，枸杞子4份，薤白2份，瓜蒌3份，砂仁2份。地龙4份，柏子仁4份，穿山龙2份，石菖蒲2份，毛冬青3份，决明子3份，合欢皮 3份，炒山楂片5份，地骨皮4份，地黄4份，郁金3份，炙甘草3份，鹿茸2份，夜交藤4份，刺蒺藜3份，翻白草2份，威灵仁2份。独活2份，桔梗2份，全蝎5份，泽泻5份，冰片2份，大枣（无核）2份，党参2份，莪术3份，生龙骨粉3份，白芍3份，丝瓜络2份，乳香或没药3份，骨碎补2份，番泻叶2份，生山药4份。生赫石4份，牡丹皮2份，蜈蚣3份，知母0.5份，制附子0.5份，生大黄1份，芒硝0.5份，玉米须3份，冬瓜皮2份，制桑枝2份，芡实0.5份，禹白附0.5份。麦冬3份，鸡血藤3份，炙桑寄生8份，炙杜仲2.5份，锁阳2.5份，柴胡2份，补骨脂2.5份，绞股蓝5份，狗脊1.5份，制川牛膝4份，薏苡仁3份，续断2份，白术2份，桃仁3份，陈皮2份，熟地黄2.5份，茯苓2.5份，厚朴2份，菟丝子3份，沙苑子1份，元胡2份，瓜萎仁3份，黑蚂蚁粉4份，墨旱莲3份，伸筋草2份，木防已2份，延胡索3份，罗布麻3份，徐长卿2份，女贞子2份，车前子2份，葶苈子2份，薄荷叶2份，南瓜籽3份，粉草薢2份，黄精5份，腊梅花2份，白前2份，海藻2份，蒲公英2份，南沙参2份，百合3份，生牡蛎4份，桂枝2份，桑叶2份，胆南星2份，草拔2份。
制备工艺同实施例1。
利用该实施例制备的产品不仅能够有效的治疗冠心病,心率失常,心绞痛之外,对于出大汗,心梗,失眠,便秘的病人疗效显著,总有效率为97.73%。
实施例3
一种治疗心脑血管疾病的中药，包含按重量份计的以下组分制成：西洋参3份，紫河车2份，紫丹参6份，红景天6份，五味子2份，当归头5份，川芎5份，远志肉4份，水蛭5份，三七5份，炒酸枣仁5份，肉苁蓉8份，雪莲2份，灵芝孢子粉4份，铁皮石斛3份，炙何首乌3份，炙茱萸肉5份，葛根5份，天麻5份，三叶鬼针草10份。降香2份，檀香2份，炙木耳6份，人参3份，益智仁3份，黄芪10份，姜黄5份，藏红花5份，赤芍2份，仙茅3份，淫羊藿5份，炙双钩藤3份，桂皮2份，枸杞子4份，薤白2份，瓜蒌3份，砂仁2份。地龙4份，柏子仁4份，穿山龙2份，石菖蒲2份，毛冬青3份，决明子3份，合欢皮 3份，炒山楂片5份，地骨皮4份，地黄4份，郁金3份，炙甘草3份，鹿茸2份，夜交藤4份，刺蒺藜3份，翻白草2份，威灵仁2份。独活2份，桔梗2份，全蝎5份，泽泻5份，冰片2份，大枣（无核）2份，党参2份，莪术3份，生龙骨粉3份，白芍3份，丝瓜络2份，乳香或没药3份，骨碎补2份，番泻叶2份，生山药4份。生赫石4份，牡丹皮2份，蜈蚣3份，知母0.5份，制附子0.5份，生大黄1份，芒硝0.5份，玉米须3份，冬瓜皮2份，制桑枝2份，芡实0.5份，禹白附0.5份。麦冬3份，鸡血藤3份，炙桑寄生8份，炙杜仲2.5份，锁阳2.5份，柴胡2份，补骨脂2.5份，绞股蓝5份，狗脊1.5份，制川牛膝4份，薏苡仁3份，续断2份，白术2份，桃仁3份，陈皮2份，熟地黄2.5份，茯苓2.5份，厚朴2份，菟丝子3份，沙苑子1份，元胡2份，瓜萎仁3份，黑蚂蚁粉4份，墨旱莲3份，伸筋草2份，木防已2份，延胡索3份，罗布麻3份，徐长卿2份，女贞子2份，车前子2份，葶苈子2份，薄荷叶2份，南瓜籽3份，粉草薢2份，黄精5份，腊梅花2份，白前2份，海藻2份，蒲公英2份，南沙参2份，百合3份，生牡蛎4份，桂枝2份，桑叶2份，胆南星2份，草拔2份。穿心莲0.5份，防风0.5份，黄柏0.5份，僵蚕1份，栀子0.5份，茯苓0.5份，制南星0.5份，郁金0.5份，苏木0.5份，金荞麦2份，刘寄奴0.5份，三棱0.5份，金竹叶1份，菟丝子0.5份，沙苑子0.5份，续断0.5份，葫芦巴0.5份，韭子0.5份，木桶0.5份。
制备工艺同实施例1。
采用该实施例制得的产品。不仅能够有效的治疗冠心病,心率失常,心绞痛之外,对于出大汗,心梗,失眠,便秘，及脑梗，脑血栓，及脑中风的病人效果同样显著，总有效率达到97.72%。

Claims (10)

1.一种治疗心脑血管疾病的中药，其特征是：包含按重量份计的以下组分制成：西洋参2-4份，紫河车1-3份，紫丹参5-7份，红景天5-7份，五味子1-3份，当归头4-6份，川芎4-6份，远志肉3-5份，水蛭4-6份，三七4-6份，炒酸枣仁4-6份，肉苁蓉7-9份，雪莲1-3份，灵芝孢子粉3-5份，铁皮石斛2-4份，炙何首乌2-4份，炙茱萸肉4-6份，葛根4-6份，天麻4-6份，三叶鬼针草9-11份。
2.如权利要求1所述的治疗心脑血管疾病的中药，其特征是：还包含按重量份计的以下组分制成：降香1-3份，檀香1-3份，炙木耳5-7份，人参2-4份，益智仁2-4份，黄芪9-11份，姜黄4-6份，藏红花4-6份，赤芍1-3份，仙茅2-4份，淫羊藿4-6份，炙双钩藤2-4份，桂皮1-3份，枸杞子3-5份，薤白1-3份，瓜蒌2-4份，砂仁1-3份。
3. 如权利要求2所述的治疗心脑血管疾病的中药，其特征是：还包含按重量份计的以下组分制成：地龙3-5份，柏子仁3-5份，穿山龙1-3份，石菖蒲1-3份，毛冬青2-4份，决明子2-4份，合欢皮 2-4份，炒山楂片4-6份，地骨皮3-5份，地黄3-5份，郁金2-4份，炙甘草2-4份，鹿茸1-3份，夜交藤3-5份，刺蒺藜2-4份，翻白草1-3份，威灵仁1-3份。
4.如权利要求3所述的治疗心脑血管疾病的中药，其特征是：还包含按重量份计的以下组分制成：独活1-3份，桔梗1-3份，全蝎4-6份，泽泻4-6份，冰片1-3份，大枣（无核）1-3份，党参1-3份，莪术2-4份，生龙骨粉2-4份，白芍2-4份，丝瓜络1-3份，乳香或没药2-4份，骨碎补1-3份，番泻叶1-3份，生山药3-5份。
5.如权利要求4所述的治疗心脑血管疾病的中药，其特征是：还包含按重量份计的以下组分制成：生赫石3-5份，牡丹皮1-3份，蜈蚣2-4份，知母0.3-0.7份，制附子0.3-0.7份，生大黄0.5-1.5份，芒硝0.3-0.7份，玉米须2-4份，冬瓜皮1-3份，制桑枝1-3份，芡实0.3-0.7份，禹白附0.3-0.7份。
6.如权利要求5所述的治疗心脑血管疾病的中药，其特征是：还包含按重量份计的以下组分制成：麦冬2-4份，鸡血藤2-4份，炙桑寄生7-9份，炙杜仲2-3份，锁阳2-3份，柴胡1-3份，补骨脂2-3份，绞股蓝4-6份，狗脊1-2份，制川牛膝3-5份，薏苡仁2-4份，续断1-3份，白术1-3份，桃仁2-4份，陈皮1-3份，熟地黄2-3份，茯苓2-3份，厚朴1-3份，菟丝子2-4份，沙苑子0.5-1.5份，元胡1-3份，瓜萎仁2-4份，黑蚂蚁粉3-5份，墨旱莲2-4份，伸筋草1-3份，木防已1-3份，延胡索2-4份，罗布麻2-4份，徐长卿1-3份，女贞子1-3份，车前子1-3份，葶苈子1-3份，薄荷叶1-3份，南瓜籽2-4份，粉草薢1-3份，黄精4-6份，腊梅花1-3份，白前1-3份，海藻1-3份，蒲公英1-3份，南沙参1-3份，百合2-4份，生牡蛎3-5份，桂枝1-3份，桑叶1-3份，胆南星1-3份，草拔1-3份。
7.如权利要求6所述的治疗心脑血管疾病的中药，其特征是，还包含按重量份计的以下组分制成：穿心莲0.3-0.7份，防风0.3-0.7份，黄柏0.3-0.5份，僵蚕0.5-1.5份，栀子0.3-0.7份，茯苓0.3-0.75份，制南星0.3-0.7份，郁金0.3-0.7份，苏木0.3-0.7份，金荞麦1-3份，刘寄奴0.3-0.7份，三棱0.3-0.7份，金竹叶0.5-1.5份，菟丝子0.3-0.7份，沙苑子0.3-0.7份，续断0.3-0.7份，葫芦巴0.3-0.7份，韭子0.3-0.7份，木桶0.3-0.7份。
8.如权利要求1-7任一权利要求所述的治疗心脑血管病的中药，其特征是：所述中药剂型为胶囊剂、粉剂。
9.根据权利要求1所述的一种治疗心脑血管病的中药制备方法，其特
征是：具体步骤为：
（1）按上述重量份进行配料；
（2）将各原料粉碎过70-90目筛，得中药组合物粉剂；将所得中药组合物粉剂按照0.25g/粒剂量按照胶囊剂的加工方法加工成胶囊状剂型。
10.如权利要求7所述的一种治疗心脑血管病的中药在制备冠心病，心肌梗塞，心绞痛的药物中的应用。
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CN109091636A (zh) * 2018-10-30 2018-12-28 右江民族医学院 一种治疗冠心病的壮药配方及其制备方法
CN109663069A (zh) * 2018-12-21 2019-04-23 上海胡庆余堂健康产业有限公司 一种疏通血管、保护心脑的复方制剂、制备方法及制备装置
CN112999328A (zh) * 2019-12-04 2021-06-22 防城港济仁堂中医门诊部 一种治疗冠心病和心梗的中药方剂及其制备方法和应用
CN111544547A (zh) * 2020-05-27 2020-08-18 贾庭山 一种治疗心脑血管疾病的中药组合物及其制备方法和应用
CN112220910A (zh) * 2020-11-26 2021-01-15 璧电户 一种包含附子的中药组合物及其制备方法
CN116019846A (zh) * 2023-02-14 2023-04-28 北京安吉贝玛健康科技有限公司 一种用于治疗心脑血管病的配方及其制备方法

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Application publication date: 20160907