CN112546148A - 一种治疗慢性心衰的中药配方及其制备方法 - Google Patents

一种治疗慢性心衰的中药配方及其制备方法 Download PDF

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CN112546148A
CN112546148A CN202011315466.2A CN202011315466A CN112546148A CN 112546148 A CN112546148 A CN 112546148A CN 202011315466 A CN202011315466 A CN 202011315466A CN 112546148 A CN112546148 A CN 112546148A
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heart failure
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余骞
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Beijing Hengde Erkang Institute Of Traditional Chinese Medicine
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Abstract

本发明提供一种治疗慢性心衰的中药配方及其制备方法，涉及医药生产技术领域。该治疗慢性心衰的中药配方，其原料按重量份包括炙黄芪50‑55份、炒枣仁20‑25份、当归20‑25份、柏子仁20‑25份、生白术20‑25份、川穹20‑25份、远志20‑25份、茯苓20‑25份、熟地20‑25份、五味子20‑25份、葶苈子50‑55份、车前子50‑55份、白芍20‑25份、麦冬20‑25份、枸杞子20‑25份、炙甘草10‑15份、木香20‑25份、夜交藤20‑25份。本发明使得治疗慢性心衰的中药适用人群更加的广泛，避免应阴虚型患者或阳虚型患者患者影响药效的发挥，且药效更好，且通过在熬煮过程中将中药搅碎使得药汁散发的更加彻底，且在熬至沸腾时将中药碾压呈纤维状，使得药物充分的散发。

Description

一种治疗慢性心衰的中药配方及其制备方法
技术领域
本发明涉及医药生产技术领域，具体为一种治疗慢性心衰的中药配方及 其制备方法。
背景技术
以中国传统医药理论指导采集、炮制、制剂，说明作用机理，指导临床 应用的药物，统称为中药。简而言之，中药就是指在中医理论指导下，用于 预防、治疗、诊断疾病并具有康复与保健作用的物质。中药主要来源于天然 药及其加工品，包括植物药、动物药、矿物药及部分化学、生物制品类药物。 由于中药以植物药居多，故有“诸药以草为本”的说法，药物之所以能够针 对病情，是由于各种药物本身各自具有若干特性和作用，前人将之称为药物 的偏性，把药物与疗效有关的性质和性能统称为药性，它包括药物发挥疗效 的物质基础和治疗过程中所体现出来的作用。它是药物性质与功能的高度概 括。研究药性形成的机制及其运用规律的理论称为药性理论，其基本内容包 括四气五味、升降浮沉、归经、有毒无毒、配伍、禁忌等。
在现有技术中慢性心衰通过中药治疗时效果差，受到阴虚型和阳虚型影 响会造成药物配方减配，造成药物效果不好，且传统的熬制方法造成药汁熬 制不彻底。
发明内容
(一)解决的技术问题
针对现有技术的不足，本发明提供了一种治疗慢性心衰的中药配方及其 制备方法，解决了治疗慢性心衰的中药适用范围低且中药有效成分熬制不彻 底的问题。
(二)技术方案
为实现以上目的，本发明通过以下技术方案予以实现：一种治疗慢性心 衰的中药配方，其原料按重量份包括炙黄芪50-55份、炒枣仁20-25份、当 归20-25份、柏子仁20-25份、生白术20-25份、川穹20-25份、远志20-25 份、茯苓20-25份、熟地20-25份、五味子20-25份、葶苈子50-55份、车 前子50-55份、白芍20-25份、麦冬20-25份、枸杞子20-25份、炙甘草10-15 份、木香20-25份、夜交藤20-25份。
优选的，所述治疗慢性心衰的中药配方中阴虚型患者另加：南沙参20-25 份、黑附片50-55份、肉桂20-25份、丹参20-25份、瓜蒌30-35份，阳虚 型患者另加：生地30-35份、天冬20-25份、桂枝20-25份、知母20-25份、 玄参30-35份。
一种治疗慢性心衰的中药的制备方法，具体制备方法如下：
步骤一：将配方中的中药通过比例称取，然后通过清水浸泡一小时，通 过毛刷将中药表面进行清洗；
步骤二：将清洗后的中药通过搅碎机进行搅碎，将搅碎后的中药放在熬 药罐内，加入清水，浸泡半个小时，且浸泡压力环境为10-15Mpa；
步骤四：步骤二中浸泡的中药放在大火进行大火熬至沸腾，沸腾十五分 钟后换小火煎煮，煎煮五十分钟后将药汁倒出；
步骤五：将煎煮后的中药进行过滤，将药渣过滤干净，将过滤药渣后的 药汁密封煮至沸腾，且药液在沸腾过程中药渣通过熬药罐内的按压辊，使得 按压辊将中药碾碎呈纤维状；
步骤六：将过滤煮沸后的药汁密封保存，将其冷却，通过真空保存，再 通过将中药通过真空无菌袋进行定量包装，且每袋定量包装的量为200毫升。
优选的，所述袋装中药每天一剂即为每天一袋，且14天为一个疗程，所 述袋装中药的保存温度为20-30摄氏度之间。
优选的，所述袋装中药在饮用前通过开水加热至四十三摄氏度至五十摄 氏度之间。
(三)有益效果
本发明提供了一种治疗慢性心衰的中药配方及其制备方法。具备以下有 益效果：
1、本发明通过设置适用于阴虚型患者和阳虚型患者的治疗慢性心衰的 中药，使得中药的适用范围更广，且阴虚型和阳虚型慢性心衰患者不会因为 药性冲突导致中药治疗不变药效吸收率低且对药物配方要求高的问题。
2、本发明在中药原料熬煮使进行充分的搅碎，使得中药熬制使药效充分 发挥出来，使得药性更加的强劲，节约中药，使得中药使用量少，降低药用 成本。
具体实施方式
下面将对本发明实施例中的技术方案进行清楚、完整地描述，显然，所 描述的实施例仅仅是本发明一部分实施例，而不是全部的实施例。基于本发 明中的实施例，本领域普通技术人员在没有做出创造性劳动前提下所获得的 所有其他实施例，都属于本发明保护的范围。
实施例一：
本发明实施例提供一种治疗慢性心衰的中药配方，其原料按重量份包括 炙黄芪50份、炒枣仁20份、当归20份、柏子仁20份、生白术20份、川穹 20份、远志20份、茯苓20份、熟地20份、五味子20份、葶苈子50份、车 前子50份、白芍20份、麦冬20份、枸杞子20份、炙甘草10份、木香20 份、夜交藤20份。
治疗慢性心衰的中药配方中阴虚型患者另加：南沙参20份、黑附片50 份、肉桂20份、丹参20份、瓜蒌30份，阳虚型患者另加：生地30份、天 冬20份、桂枝20份、知母20份、玄参30份。
一种治疗慢性心衰的中药的制备方法，具体制备方法如下：
步骤一：将配方中的中药通过比例称取，然后通过清水浸泡一小时，通 过毛刷将中药表面进行清洗；
步骤二：将清洗后的中药通过搅碎机进行搅碎，将搅碎后的中药放在熬 药罐内，加入清水，浸泡半个小时，且浸泡压力环境为10Mpa；
步骤四：步骤二中浸泡的中药放在大火进行大火熬至沸腾，沸腾十五分 钟后换小火煎煮，煎煮五十分钟后将药汁倒出；
步骤五：将煎煮后的中药进行过滤，将药渣过滤干净，将过滤药渣后的 药汁密封煮至沸腾，且药液在沸腾过程中药渣通过熬药罐内的按压辊，使得 按压辊将中药碾碎呈纤维状；
步骤六：将过滤煮沸后的药汁密封保存，将其冷却，通过真空保存，再 通过将中药通过真空无菌袋进行定量包装，且每袋定量包装的量为200毫升。
袋装中药每天一剂即为每天一袋，且14天为一个疗程，袋装中药的保存 温度为20摄氏度之间。袋装中药在饮用前通过开水加热至四十三摄氏度。
实施例二：
其原料按重量份包括炙黄芪51份、炒枣仁21份、当归21份、柏子仁21 份、生白术21份、川穹21份、远志21份、茯苓21份、熟地21份、五味子 21份、葶苈子51份、车前子51份、白芍21份、麦冬21份、枸杞子21份、 炙甘草11份、木香21份、夜交藤21份。
治疗慢性心衰的中药配方中阴虚型患者另加：南沙参21份、黑附片51 份、肉桂21份、丹参21份、瓜蒌31份，阳虚型患者另加：生地31份、天 冬21份、桂枝21份、知母21份、玄参31份。
实施例三：
其原料按重量份包括炙黄芪52份、炒枣仁22份、当归22份、柏子仁22 份、生白术22份、川穹22份、远志22份、茯苓22份、熟地22份、五味子 22份、葶苈子52份、车前子52份、白芍22份、麦冬22份、枸杞子22份、 炙甘草12份、木香22份、夜交藤22份。
治疗慢性心衰的中药配方中阴虚型患者另加：南沙参22份、黑附片52 份、肉桂22份、丹参22份、瓜蒌32份，阳虚型患者另加：生地32份、天 冬22份、桂枝22份、知母22份、玄参32份。
实施例四：
其原料按重量份包括炙黄芪53份、炒枣仁23份、当归23份、柏子仁23 份、生白术23份、川穹23份、远志23份、茯苓23份、熟地23份、五味子 23份、葶苈子53份、车前子53份、白芍23份、麦冬23份、枸杞子23份、 炙甘草13份、木香23份、夜交藤23份。
治疗慢性心衰的中药配方中阴虚型患者另加：南沙参23份、黑附片53 份、肉桂23份、丹参23份、瓜蒌33份，阳虚型患者另加：生地33份、天 冬23份、桂枝23份、知母23份、玄参33份。
实施例五：
其原料按重量份包括炙黄芪54份、炒枣仁24份、当归24份、柏子仁24 份、生白术24份、川穹24份、远志24份、茯苓24份、熟地24份、五味子 24份、葶苈子54份、车前子54份、白芍24份、麦冬24份、枸杞子24份、 炙甘草14份、木香24份、夜交藤24份。
治疗慢性心衰的中药配方中阴虚型患者另加：南沙参24份、黑附片54 份、肉桂24份、丹参24份、瓜蒌34份，阳虚型患者另加：生地34份、天 冬24份、桂枝24份、知母24份、玄参34份。
实施例六：
其原料按重量份包括炙黄芪55份、炒枣仁25份、当归25份、柏子仁25 份、生白术25份、川穹25份、远志25份、茯苓25份、熟地25份、五味子 25份、葶苈子55份、车前子55份、白芍25份、麦冬25份、枸杞子25份、 炙甘草15份、木香25份、夜交藤25份。
治疗慢性心衰的中药配方中阴虚型患者另加：南沙参25份、黑附片55 份、肉桂25份、丹参25份、瓜蒌35份，阳虚型患者另加：生地35份、天 冬25份、桂枝25份、知母25份、玄参35份。
各实施例bnp指数大于1006ng/L的患者bnp指数变化时间
Figure BDA0002791217920000061
尽管已经示出和描述了本发明的实施例，对于本领域的普通技术人员而 言，可以理解在不脱离本发明的原理和精神的情况下可以对这些实施例进行 多种变化、修改、替换和变型，本发明的范围由所附权利要求及其等同物限 定。

Claims (5)

1.一种治疗慢性心衰的中药配方，其特征在于：其原料按重量份包括炙黄芪50-55份、炒枣仁20-25份、当归20-25份、柏子仁20-25份、生白术20-25份、川穹20-25份、远志20-25份、茯苓20-25份、熟地20-25份、五味子20-25份、葶苈子50-55份、车前子50-55份、白芍20-25份、麦冬20-25份、枸杞子20-25份、炙甘草10-15份、木香20-25份、夜交藤20-25份。
2.根据权利要求1所述的一种治疗慢性心衰的中药配方，其特征在于：所述治疗慢性心衰的中药配方中阴虚型患者另加：南沙参20-25份、黑附片50-55份、肉桂20-25份、丹参20-25份、瓜蒌30-35份，阳虚型患者另加：生地30-35份、天冬20-25份、桂枝20-25份、知母20-25份、玄参30-35份。
3.一种治疗慢性心衰的中药的制备方法，其特征在于：具体制备方法如下：
步骤一：将配方中的中药通过比例称取，然后通过清水浸泡一小时，通过毛刷将中药表面进行清洗；
步骤二：将清洗后的中药通过搅碎机进行搅碎，将搅碎后的中药放在熬药罐内，加入清水，浸泡半个小时，且浸泡压力环境为10-15Mpa；
步骤四：步骤二中浸泡的中药放在大火进行大火熬至沸腾，沸腾十五分钟后换小火煎煮，煎煮五十分钟后将药汁倒出；
步骤五：将煎煮后的中药进行过滤，将药渣过滤干净，将过滤药渣后的药汁密封煮至沸腾，且药液在沸腾过程中药渣通过熬药罐内的按压辊，使得按压辊将中药碾碎呈纤维状；
步骤六：将过滤煮沸后的药汁密封保存，将其冷却，通过真空保存，再通过将中药通过真空无菌袋进行定量包装，且每袋定量包装的量为200毫升。
4.根据权利要求3所述的一种治疗慢性心衰的中药的制备方法，其特征在于：所述袋装中药每天一剂即为每天一袋，且14天为一个疗程，所述袋装中药的保存温度为20-30摄氏度之间。
5.根据权利要求3所述的一种治疗慢性心衰的中药的制备方法，其特征在于：所述袋装中药在饮用前通过开水加热至四十三摄氏度至五十摄氏度之间。
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