CN105919124A - Fresh ginger capsule preparation for preventing nausea and vomiting and preparation method thereof - Google Patents

Fresh ginger capsule preparation for preventing nausea and vomiting and preparation method thereof Download PDF

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Publication number
CN105919124A
CN105919124A CN201610262382.4A CN201610262382A CN105919124A CN 105919124 A CN105919124 A CN 105919124A CN 201610262382 A CN201610262382 A CN 201610262382A CN 105919124 A CN105919124 A CN 105919124A
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CN
China
Prior art keywords
powder
vomiting
fructus
zingiberis recens
rhizoma zingiberis
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Pending
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CN201610262382.4A
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Chinese (zh)
Inventor
金如兰
韩菲
金如林
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Tongling City Shejia Tribute Ginger Plant
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Tongling City Shejia Tribute Ginger Plant
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Priority to CN201610262382.4A priority Critical patent/CN105919124A/en
Publication of CN105919124A publication Critical patent/CN105919124A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention discloses a fresh ginger capsule preparation for preventing nausea and vomiting and a preparation method thereof. The fresh ginger capsule preparation consists of the following raw materials: fresh gingers, wheat germ, egg white powder, dried Chinese yams, pine nut kernels, rosa roxburghii, papayas, carrot powder, yellow rice wine, chenopodium quinoa, elaeagnus angustifolia, etc. The beneficial effects are as follows: the fresh gingers have functions of preventing nausea and stopping vomiting. A research proves that the effective rates of the fresh ginger dry powder on treating the symptoms of headaches, dizziness, nausea, vomiting caused by exercises reach 90%, and the drug efficacy is sustainable for 4 hours or above. The active ingredients in the fresh gingers are extracted, the raw materials in a scientific ratio are prepared into the capsule preparation, and the capsule preparation is convenient for consumption and carrying, and has obvious effects of preventing motion sickness and seasickness and relieving dizziness after exercises.

Description

A kind of Rhizoma Zingiberis Recens capsule preparations preventing nausea and vomiting and preparation method thereof
Technical field
The present invention relates to technical field of health care food, particularly relate to a kind of Rhizoma Zingiberis Recens capsule preparations preventing nausea and vomiting and Preparation method.
Background technology
Rhizoma Zingiberis Recens common name Rhizoma Zingiberis Recens, for the fresh and tender stem of zingiber, belongs to perennial herb perennial plant and originates in Southeast Asia, and China is certainly Gu just has cultivation, Sichuan, middle part and southern areas to be generally distributed, and composition and the function of Rhizoma Zingiberis Recens are studied widely, the perfume (or spice) of Rhizoma Zingiberis Recens Gas and local flavor depend on its ethereal oil Rhizoma Zingiberis Recens quintessence oil, and the pungent local flavor of Rhizoma Zingiberis Recens is peppery essentially from the Rhizoma Zingiberis Recens in nonvolatile oil ginger oil resin Containing many trace element and the composition useful to human body in element, and Rhizoma Zingiberis Recens.Containing a small amount of volatile oil, fat, pungent in Rhizoma Zingiberis Recens Capsaicin, protein, vitamin, starch and mineral element, containing several amino acids, vitamin and hexahydrocurcumin and ferrum, copper, manganese, The trace element such as zinc, chromium, nickel, cobalt, germanium.The active ingredient of Rhizoma Zingiberis Recens mainly includes volatile oil and gingerol, and gingerol is in Rhizoma Zingiberis Recens There is the general name of pungent one class material, for the mixture of many kinds of substance composition.Gingerol is not only the master of Rhizoma Zingiberis Recens characteristic flavor Want taste compound, be also Rhizoma Zingiberis Recens be the major function factor of multiple pharmacological effect.The present invention combines in Rhizoma Zingiberis Recens beneficiating ingredient with many Plant natural health food and make the formulation products with health-care effect, meet the popular demand to health-oriented products.
Summary of the invention
The object of the invention is contemplated to make up the defect of prior art, it is provided that a kind of Rhizoma Zingiberis Recens capsule system preventing nausea and vomiting Agent and preparation method thereof.
The present invention is achieved by the following technical solutions:
A kind of Rhizoma Zingiberis Recens capsule preparations preventing nausea and vomiting, is made up of the raw material of following weight portion: Rhizoma Zingiberis Recens 330-340, wheat germ Bud 34-35, meringue powder 12-13, Dry Rhizoma Dioscoreae 27-28, Semen pini koraiensis 9-10, Fructus Rosae Normalis 20-21, Fructus Caricae 11-12, Radix Dauci Sativae powder 3-4, Yellow wine 14-15, Quinoa 22-23, Fructus Elaeagni Angustifoliae 5-6, water are appropriate.
The preparation method of the Rhizoma Zingiberis Recens capsule preparations according to the prevention nausea and vomiting described in claim l, comprises the steps:
(1) choose fresh high-quality to clean peeling without the Rhizoma Zingiberis Recens gone mouldy and cut fritter, blanching 3-5 minute in boiling water, pull out cool to Carrying out micronizing after room temperature, add 0.1-0.2% ascorbic acid mix homogeneously, the water adding 5-6 times amount is placed in 60-65 DEG C of temperature Heating in water bath under the conditions of degree, ultrasonic extraction 3-4 time, filter off residue after taking out cooling, be placed in a centrifuge centrifugal treating 20-30 Minute, centrifuge speed is 1800-2000r/min, extracts supernatant standby;
(2) by obtained supernatant through Rotary Evaporators concentration, soluble solid is 30-40%, is concentrated by gained Liquid crosses macroporous adsorptive resins;With 0-99% ethanol, macroporous adsorbent resin is carried out gradient elution successively, collect eluate, concentrate, Carry out micronizing process after drying, obtain effective components of ginger superfine powder;
(3) Fructus Rosae Normalis, Fructus Caricae, Fructus Elaeagni Angustifoliae take sarcocarp, and cleaning with Fructus Tritici aestivi, Dry Rhizoma Dioscoreae, Semen pini koraiensis, Quinoa and being placed on concentration is 3- The saline of 4% soaks 40-50 minute, pulls out and after cleaning, add appropriate water polishing pulping, mix homogeneously with other residual componentss Ultrafiltrate is obtained by ultrafiltration apparatus after processing;
(4) being stirred by step (3) gained ultrafiltrate addition 4-5% modifying agent, the composition of modifying agent is maltodextrin, xanthan Glue, sodium bicarbonate, ratio is 5:4:1, pulverizes after vacuum lyophilization, obtains nutrition and adds lyophilized powder;
(5) water of effective components of ginger superfine powder, nutrition interpolation lyophilized powder addition mass parts 2-3 times amount is stirred as bag Core material, with konjaku powder, maltodextrin, soybean protein isolate mixture for containment wall material, containment wall material component ratio is 2: 1:1, spray-dried equipment microcapsule granulating technique makes microcapsule, then after 121-130 DEG C of high-temperature short-time sterilization processes Make capsule preparations, pack.
The invention have the advantage that Rhizoma Zingiberis Recens have prevent from feeling sick, antiemetic effect, there are some researches prove, Rhizoma Zingiberis Recens dry powder to because of Headache that motion causes, dizziness, the effective percentage of the symptom such as Nausea and vomiting reach 90%, and sustainable more than 4 hours of drug effect, the present invention Extract effective ingredient in Rhizoma Zingiberis Recens and make instant edible and the capsule preparations carried through scientific matching, pre-carsickness-proof, seasick, alleviate Dizzy symptom after motion, has obvious effect.
Detailed description of the invention
A kind of Rhizoma Zingiberis Recens capsule preparations preventing nausea and vomiting, is made up of the raw material of following weight portion: Rhizoma Zingiberis Recens 330, wheat germ Bud 34, meringue powder 12, Dry Rhizoma Dioscoreae 27, Semen pini koraiensis 9, Fructus Rosae Normalis 20, Fructus Caricae 11, Radix Dauci Sativae powder 3, yellow wine 14, Quinoa 22, Fructus Elaeagni Angustifoliae 5, Water is appropriate.
The preparation method of the Rhizoma Zingiberis Recens capsule preparations according to the prevention nausea and vomiting described in claim l, comprises the steps:
(1) choosing fresh high-quality to clean peeling without the Rhizoma Zingiberis Recens gone mouldy and cut fritter, in boiling water, blanching 3 minutes, pull out and cool to room Carrying out micronizing after temperature, add 0.1% ascorbic acid mix homogeneously, the water adding 5 times amount is placed in water-bath under 60 DEG C of temperature conditionss Heating, ultrasonic extraction 3 times, filter off residue after taking out cooling, be placed in a centrifuge centrifugal treating 20 minutes, centrifuge speed is 1800r/min, extracts supernatant standby;
(2) by obtained supernatant through Rotary Evaporators concentration, soluble solid is 30%, by gained concentrated solution Cross macroporous adsorptive resins;With 0-99% ethanol, macroporous adsorbent resin is carried out gradient elution successively, collect eluate, concentrate, do Carry out micronizing process after dry, obtain effective components of ginger superfine powder;
(3) Fructus Rosae Normalis, Fructus Caricae, Fructus Elaeagni Angustifoliae take sarcocarp, and cleaning with Fructus Tritici aestivi, Dry Rhizoma Dioscoreae, Semen pini koraiensis, Quinoa and being placed on concentration is 3% Saline in soak 40 minutes, pull out and after cleaning, add appropriate water polishing pulping, warp after mixing homogeneously with other residual componentss Ultrafiltration apparatus obtains ultrafiltrate after processing;
(4) step (3) gained ultrafiltrate is added 4% modifying agent to stir, the composition of modifying agent be maltodextrin, xanthan gum, Sodium bicarbonate, ratio is 5:4:1, pulverizes after vacuum lyophilization, obtains nutrition and adds lyophilized powder;
(5) water of effective components of ginger superfine powder, nutrition interpolation lyophilized powder addition mass parts 2 times amount is stirred as cored Material, with konjaku powder, maltodextrin, soybean protein isolate mixture for containment wall material, containment wall material component ratio is 2:1: 1, spray-dried equipment microcapsule granulating technique makes microcapsule, then makes glue after 130 DEG C of high-temperature short-time sterilization process Capsule preparation, packs.

Claims (2)

1. the Rhizoma Zingiberis Recens capsule preparations preventing nausea and vomiting, it is characterised in that be made up of the raw material of following weight portion: Rhizoma Zingiberis Recens 330-340, Fructus Tritici aestivi 34-35, meringue powder 12-13, Dry Rhizoma Dioscoreae 27-28, Semen pini koraiensis 9-10, Fructus Rosae Normalis 20-21, Fructus Caricae 11- 12, Radix Dauci Sativae powder 3-4, yellow wine 14-15, Quinoa 22-23, Fructus Elaeagni Angustifoliae 5-6, water are appropriate.
2. according to the preparation method of the Rhizoma Zingiberis Recens capsule preparations preventing nausea and vomiting described in claim l, it is characterised in that include Following steps:
(1) choose fresh high-quality to clean peeling without the Rhizoma Zingiberis Recens gone mouldy and cut fritter, blanching 3-5 minute in boiling water, pull out cool to Carrying out micronizing after room temperature, add 0.1-0.2% ascorbic acid mix homogeneously, the water adding 5-6 times amount is placed in 60-65 DEG C of temperature Heating in water bath under the conditions of degree, ultrasonic extraction 3-4 time, filter off residue after taking out cooling, be placed in a centrifuge centrifugal treating 20-30 Minute, centrifuge speed is 1800-2000r/min, extracts supernatant standby;
(2) by obtained supernatant through Rotary Evaporators concentration, soluble solid is 30-40%, is concentrated by gained Liquid crosses macroporous adsorptive resins;With 0-99% ethanol, macroporous adsorbent resin is carried out gradient elution successively, collect eluate, concentrate, Carry out micronizing process after drying, obtain effective components of ginger superfine powder;
(3) Fructus Rosae Normalis, Fructus Caricae, Fructus Elaeagni Angustifoliae take sarcocarp, and cleaning with Fructus Tritici aestivi, Dry Rhizoma Dioscoreae, Semen pini koraiensis, Quinoa and being placed on concentration is 3- The saline of 4% soaks 40-50 minute, pulls out and after cleaning, add appropriate water polishing pulping, mix homogeneously with other residual componentss Ultrafiltrate is obtained by ultrafiltration apparatus after processing;
(4) being stirred by step (3) gained ultrafiltrate addition 4-5% modifying agent, the composition of modifying agent is maltodextrin, xanthan Glue, sodium bicarbonate, ratio is 5:4:1, pulverizes after vacuum lyophilization, obtains nutrition and adds lyophilized powder;
(5) water of effective components of ginger superfine powder, nutrition interpolation lyophilized powder addition mass parts 2-3 times amount is stirred as bag Core material, with konjaku powder, maltodextrin, soybean protein isolate mixture for containment wall material, containment wall material component ratio is 2: 1:1, spray-dried equipment microcapsule granulating technique makes microcapsule, then after 121-130 DEG C of high-temperature short-time sterilization processes Make capsule preparations, pack.
CN201610262382.4A 2016-04-26 2016-04-26 Fresh ginger capsule preparation for preventing nausea and vomiting and preparation method thereof Pending CN105919124A (en)

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Application Number Priority Date Filing Date Title
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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1189979A (en) * 1998-01-07 1998-08-12 张铁山 Tasty health ginger and its production
CN101658662A (en) * 2008-08-28 2010-03-03 牛全道 Smoking quitting wine and preparation method thereof
CN103300307A (en) * 2013-05-15 2013-09-18 高跃忠 Preparation process of ginger extract
CN103623373A (en) * 2013-12-03 2014-03-12 江苏省人民医院 Orally-taken traditional Chinese medicine
CN103653136A (en) * 2013-12-02 2014-03-26 孙淑芬 Apple pineapple raw ginger juice and producing method thereof
CN104824215A (en) * 2015-04-20 2015-08-12 仝玉红 Chinese-date and fresh ginger life-preserving traditional Chinese medicine tea beverage and preparation method
CN104906540A (en) * 2015-06-09 2015-09-16 山东省医学科学院附属医院 Preparation method and application of traditional Chinese medicine ointment for preventing and treating delayed nausea and vomiting caused by chemotherapy

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1189979A (en) * 1998-01-07 1998-08-12 张铁山 Tasty health ginger and its production
CN101658662A (en) * 2008-08-28 2010-03-03 牛全道 Smoking quitting wine and preparation method thereof
CN103300307A (en) * 2013-05-15 2013-09-18 高跃忠 Preparation process of ginger extract
CN103653136A (en) * 2013-12-02 2014-03-26 孙淑芬 Apple pineapple raw ginger juice and producing method thereof
CN103623373A (en) * 2013-12-03 2014-03-12 江苏省人民医院 Orally-taken traditional Chinese medicine
CN104824215A (en) * 2015-04-20 2015-08-12 仝玉红 Chinese-date and fresh ginger life-preserving traditional Chinese medicine tea beverage and preparation method
CN104906540A (en) * 2015-06-09 2015-09-16 山东省医学科学院附属医院 Preparation method and application of traditional Chinese medicine ointment for preventing and treating delayed nausea and vomiting caused by chemotherapy

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Application publication date: 20160907