CN105919093A - Qi-replenishing and spleen-tonifying compound lingzhi mushroom preparation and preparation method thereof - Google Patents
Qi-replenishing and spleen-tonifying compound lingzhi mushroom preparation and preparation method thereof Download PDFInfo
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The invention discloses a Qi-replenishing and spleen-tonifying compound lingzhi mushroom preparation and a preparation method thereof. The Qi-replenishing and spleen-tonifying compound lingzhi mushroom preparation comprises three ingredients, including ingredient A, ingredient B and ingredient C. The ingredient A, the ingredient B and the ingredient C are respectively composed of the following prescription components in parts by weight: the ingredient A comprises 35-38 parts of lingzhi mushrooms, 10-12 parts of shiitake mushrooms, 6-9 parts of abalone mushrooms and 6-8 parts of tremella fuciformis; the ingredient B comprises 13-16 parts of coix seeds, 5-8 parts of white hyacinth beans and 5-8 parts of millets; and the ingredient C comprises 10-20 parts of fallopia multiflora, 9-15 parts of polygonatum sibiricum, 10-15 parts of euryale ferox seeds, 3-9 parts of gymnadenia conopsea, 9-15 parts of astragalus propinquus, 6-12 parts of white atractylodes rhizomes, 9-13 parts of eleutherococcus senticosus, 3-5 parts of dried orange peels and 3-4 parts of pinellia ternate. The prepared compound lingzhi mushroom preparation has auxiliary protective effects to the injured spleen, and has comprehensive health-care effects of reinforcing physique, nourishing blood, benefiting liver, improving kidney essence, tonifying kidney, strengthening bones and tendons as well as accelerating blood-microcirculation. Moreover, the preparation method disclosed by the invention is simple, small in investment, short in process and high in production efficiency.
Description
Technical field
The invention belongs to health product technology field, be specifically related to a kind of benefit gas tonifying spleen lucid ganoderma complex preparation and preparation method thereof.
Background technology
Spleen is important lymphoid organ, has hematopoiesis, hemofiltration, removing aging haemocyte and participates in the functions such as immune response.Because it enriches containing blood volume, it is possible to urgent to other organ supplemental blood, so there being the title of " human body blood bank ", there is the title of the foundation of acquired constitution.Society, along with the increase of people's operating pressure and various dinner party are continuous, stays up late, drinks and the factor such as smoking all causes the infringement in various degree of the spleen of people, and therefore, the functional health care product with beneficial gas tonifying spleen effect is increasingly liked by consumer.
Glossy ganoderma is the fructification of On Polyporaceae glossy ganoderma.There is invigorating qi for tranquilization, relieving cough and asthma effect, cough breathe heavily for dizziness egersis, palpitation, neurasthenia, consumptive disease, the effect promoted longevity.GL-B is present in mycelium and the fructification of Ganoderma fungi, it is made up of, has the glucan of helical form stereo formation (tertiary structure) three strands of monose chains, immunity of organisms can be improved, accelerate blood microcirculation, the invalid oxygen demand improved under blood oxygen ability, reduction body inactive state, elimination interior free yl and improve the closed stratum of body cell film, anti-radiation, improve liver, marrow, blood synthetic DNA, RNA and the ability of protein, extend the life-span etc..In the prior art, Lingzhu ' product prescription is single, it is only simply formulated with Ganodenna Lucidum P.E, the drug effect of glossy ganoderma cannot be given full play to, therefore, utilize the GL-B extracted from glossy ganoderma the synthesis of compatibility various ingredients to have the compound preparation of beneficial gas tonifying spleen effect, very big meaning will be played for improving function of human body.
Summary of the invention
Present invention aims to prior art not enough, it is provided that a kind of benefit gas tonifying spleen lucid ganoderma complex preparation and preparation method thereof.Obtained compound preparation not only has auxiliary protection function to the spleen of damage, have simultaneously build up health, the benefit that nourishes blood liver, controlling nocturnal emission with astringent drugs kidney-nourishing, muscle reinforcing and bone strengthening and accelerate the comprehensive health-care effect of blood microcirculation.
For achieving the above object, the present invention adopts the following technical scheme that
A kind of benefit gas tonifying spleen lucid ganoderma complex preparation, its raw material includes tri-components of A, B and C, and in terms of parts by weight, the formula composition of tri-components of A, B and C is as follows:
Component A:
Glossy ganoderma 35 ~ 38 parts, 10 ~ 12 parts of mushroom, grey mushroom (abalonelike) 6 ~ 9 parts and 6 ~ 8 parts of white fungus；
B component:
Coix seed 13 ~ 16 parts, Semen Lablab Album 5 ~ 8 parts and maize 5 ~ 8 parts；
Component C:
The fleece-flower root 10 ~ 20 parts, sealwort 9 ~ 15 parts, Gorgon fruit 10 ~ 15 parts, Buddha's hand join 3 ~ 9 parts, the Radix Astragali 9 ~ 15 parts, the bighead atractylodes rhizome 6 ~ 12 parts, wilsonii 9 ~ 13 parts, dried orange peel 3 ~ 5 parts and the tuber of pinellia 3 ~ 4 parts.
Preferably, a kind of benefit gas tonifying spleen lucid ganoderma complex preparation, its raw material includes tri-components of A, B and C, and in terms of parts by weight, the formula composition of tri-components of A, B and C is as follows:
Component A:
Glossy ganoderma 36 parts, 12 parts of mushroom, grey mushroom (abalonelike) 7.5 parts and 6 parts of white fungus；
B component:
Coix seed 15 parts, Semen Lablab Album 6 parts and maize 7 parts；
Component C:
The fleece-flower root 15 parts, sealwort 12 parts, Gorgon fruit 12 parts, Buddha's hand join 5 parts, the Radix Astragali 10 parts, the bighead atractylodes rhizome 8 parts, wilsonii 11 parts, dried orange peel 4 parts and the tuber of pinellia 3.5 parts.
The preparation method of benefit gas tonifying spleen lucid ganoderma complex preparation as above, specifically includes following steps:
(1) preparation of GL-B: add in the water of 15 times of quality after glossy ganoderma is pulverized, keep 90 minutes after boiling, filter, the ethanol of 95wt% is added in gained filter residue, and extract 3 hours at 90 DEG C, filter to obtain glossy ganoderma slag, after being dried at 50 DEG C by glossy ganoderma slag and after ultramicro grinding, excessively 120 mesh sieves, obtain glossy ganoderma powder；The glossy ganoderma powder of gained is joined in the water that quality is glossy ganoderma powder 20 times, regulation pH is 4, add complex enzyme, the addition of complex enzyme is to carry out enzymolysis and extraction under the 1% of glossy ganoderma powder quality, stirring, and enzymolysis and extraction condition is: hydrolysis temperature is 45 ~ 55 DEG C, enzymolysis time is 60 ~ 120 minutes, described complex enzyme is Fungal Acid Protease and cellulase 1:3 in mass ratio mixing, and enzymolysis and extraction terminates rear centrifugation, takes supernatant and is enzyme-extracting solution；The daltonian film of gained enzyme-extracting solution molecular cut off 12000 ~ 15000 is carried out ultrafiltration, collects ultrafiltration permeate；Gained ultrafiltration permeate is concentrated in vacuo to the 30% of original volume, obtains concentrate；Being joined by gained concentrate in the ethanol of 95wt%, after mixing, ethanol mass percent becomes 60wt%, stands 6 ~ 8h, centrifugal segregation supernatant, collects precipitation, obtains GL-B after freeze-drying；
(2) by after clean to mushroom, grey mushroom (abalonelike) and white fungus drying, pulverize and cross 80 ~ 100 mesh sieves, by the mixing of gained powder irradiation sterilization, obtaining composite bacterium powder, standby；
(3) Semen Lablab Album selected and clean after, roast, roast temperature 150 DEG C, 20 minutes time, be cooled to room temperature, after pulverizing cross 100 mesh sieves, obtain Semen Lablab Album powder；Coix seed and maize is selected and cleans post-drying, pulverizes together, and crosses after 100 mesh sieves and be mixed together uniformly with Semen Lablab Album powder；
(4) take the fleece-flower root, sealwort, Gorgon fruit, Buddha's hand ginseng, the Radix Astragali, the bighead atractylodes rhizome, wilsonii, dried orange peel and the tuber of pinellia, add the ethanol solution of 5 times of weight 75wt%, extract 2 hours at a temperature of 90 DEG C, extract twice, filter, in filter residue, add the water of 10 times of weight, boil, extract 1.5 hours, filter, merge No. 3 extracts and be concentrated to give medicinal extract, gained medicinal extract is spray-dried, and cross 100 mesh sieves, collect dry powder；
(5) composite bacterium powder that the GL-B that step (1) prepared, step (2) obtain, step (3) pulverize after material and the dry powder blend of step (4) uniform；
(6) auxiliary material that mixture step (5) obtained adds pharmaceutically prepares capsule, granule, pill, powder or tablet.
The beneficial effects of the present invention is:The present invention combines modern pharmacological research according to traditional medicine theory; the GL-B of one of composition maximally effective in glossy ganoderma is extracted; can the most directly give play to the invigorating qi for tranquilization of glossy ganoderma, invigorated the spleen and benefited qi and improve the function of immunity; synergistic function can be played again with other compatibility composition; meet the phase minister of traditional medicine, assist opinion with a task mutually; not only to damage spleen have auxiliary protection function, have simultaneously build up health, nourish blood benefit liver, controlling nocturnal emission with astringent drugs kidney-nourishing, muscle reinforcing and bone strengthening and accelerate blood microcirculation comprehensive health-care effect；Additionally, the preparation method of the present invention is simple, small investment, flow process is short, and production efficiency is high.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention will be further described, but the present invention is not limited only to these embodiments.
Embodiment 1
A kind of benefit gas tonifying spleen lucid ganoderma complex preparation, its raw material includes tri-components of A, B and C, and in terms of parts by weight, the formula composition of tri-components of A, B and C is as follows:
Component A:
Glossy ganoderma 35 parts, 10 parts of mushroom, grey mushroom (abalonelike) 6 parts and 6 parts of white fungus；
B component:
Coix seed 13 parts, Semen Lablab Album 5 parts and maize 5 parts；
Component C:
The fleece-flower root 10 parts, sealwort 9 parts, Gorgon fruit 10 parts, Buddha's hand join 3 parts, the Radix Astragali 9 parts, the bighead atractylodes rhizome 6 parts, wilsonii 9 parts, dried orange peel 3 parts and the tuber of pinellia 3 parts.
The preparation method of benefit gas tonifying spleen lucid ganoderma complex preparation as above, specifically includes following steps:
(1) preparation of GL-B: add in the water of 15 times of quality after glossy ganoderma is pulverized, keep 90 minutes after boiling, filter, the ethanol of 95wt% is added in gained filter residue, and extract 3 hours at 90 DEG C, filter to obtain glossy ganoderma slag, after being dried at 50 DEG C by glossy ganoderma slag and after ultramicro grinding, excessively 120 mesh sieves, obtain glossy ganoderma powder；The glossy ganoderma powder of gained is joined in the water that quality is glossy ganoderma powder 20 times, regulation pH is 4, add complex enzyme, the addition of complex enzyme is to carry out enzymolysis and extraction under the 1% of glossy ganoderma powder quality, stirring, and enzymolysis and extraction condition is: hydrolysis temperature is 45 DEG C, enzymolysis time is 120 minutes, described complex enzyme is Fungal Acid Protease and cellulase 1:3 in mass ratio mixing, and enzymolysis and extraction terminates rear centrifugation, takes supernatant and is enzyme-extracting solution；The daltonian film of gained enzyme-extracting solution molecular cut off 12000 is carried out ultrafiltration, collects ultrafiltration permeate；Gained ultrafiltration permeate is concentrated in vacuo to the 30% of original volume, obtains concentrate；Being joined by gained concentrate in the ethanol of 95wt%, after mixing, ethanol mass percent becomes 60wt%, stands 6h, centrifugal segregation supernatant, collects precipitation, obtains GL-B after freeze-drying；
(2) by after clean to mushroom, grey mushroom (abalonelike) and white fungus drying, pulverize and cross 80 mesh sieves, by the mixing of gained powder irradiation sterilization, obtaining composite bacterium powder, standby；
(3) Semen Lablab Album selected and clean after, roast, roast temperature 150 DEG C, 20 minutes time, be cooled to room temperature, after pulverizing cross 100 mesh sieves, obtain Semen Lablab Album powder；Coix seed and maize is selected and cleans post-drying, pulverizes together, and crosses after 100 mesh sieves and be mixed together uniformly with Semen Lablab Album powder；
(4) take the fleece-flower root, sealwort, Gorgon fruit, Buddha's hand ginseng, the Radix Astragali, the bighead atractylodes rhizome, wilsonii, dried orange peel and the tuber of pinellia, add the ethanol solution of 5 times of weight 75wt%, extract 2 hours at a temperature of 90 DEG C, extract twice, filter, in filter residue, add the water of 10 times of weight, boil, extract 1.5 hours, filter, merge No. 3 extracts and be concentrated to give medicinal extract, gained medicinal extract is spray-dried, and cross 100 mesh sieves, collect dry powder；
(5) composite bacterium powder that the GL-B that step (1) prepared, step (2) obtain, step (3) pulverize after material and the dry powder blend of step (4) uniform；
(6) auxiliary material that mixture step (5) obtained adds pharmaceutically prepares capsule, granule, pill, powder or tablet.
Embodiment 2
A kind of benefit gas tonifying spleen lucid ganoderma complex preparation, its raw material includes tri-components of A, B and C, and in terms of parts by weight, the formula composition of tri-components of A, B and C is as follows:
Component A:
Glossy ganoderma 38 parts, 12 parts of mushroom, grey mushroom (abalonelike) 9 parts and 8 parts of white fungus；
B component:
Coix seed 16 parts, Semen Lablab Album 8 parts and maize 8 parts；
Component C:
The fleece-flower root 20 parts, sealwort 15 parts, Gorgon fruit 15 parts, Buddha's hand join 9 parts, the Radix Astragali 15 parts, the bighead atractylodes rhizome 12 parts, wilsonii 13 parts, dried orange peel 5 parts and the tuber of pinellia 4 parts.
The preparation method of benefit gas tonifying spleen lucid ganoderma complex preparation as above, specifically includes following steps:
(1) preparation of GL-B: add in the water of 15 times of quality after glossy ganoderma is pulverized, keep 90 minutes after boiling, filter, the ethanol of 95wt% is added in gained filter residue, and extract 3 hours at 90 DEG C, filter to obtain glossy ganoderma slag, after being dried at 50 DEG C by glossy ganoderma slag and after ultramicro grinding, excessively 120 mesh sieves, obtain glossy ganoderma powder；The glossy ganoderma powder of gained is joined in the water that quality is glossy ganoderma powder 20 times, regulation pH is 4, add complex enzyme, the addition of complex enzyme is to carry out enzymolysis and extraction under the 1% of glossy ganoderma powder quality, stirring, and enzymolysis and extraction condition is: hydrolysis temperature is 55 DEG C, enzymolysis time is 60 minutes, described complex enzyme is Fungal Acid Protease and cellulase 1:3 in mass ratio mixing, and enzymolysis and extraction terminates rear centrifugation, takes supernatant and is enzyme-extracting solution；The daltonian film of gained enzyme-extracting solution molecular cut off 15000 is carried out ultrafiltration, collects ultrafiltration permeate；Gained ultrafiltration permeate is concentrated in vacuo to the 30% of original volume, obtains concentrate；Being joined by gained concentrate in the ethanol of 95wt%, after mixing, ethanol mass percent becomes 60wt%, stands 8h, centrifugal segregation supernatant, collects precipitation, obtains GL-B after freeze-drying；
(2) by after clean to mushroom, grey mushroom (abalonelike) and white fungus drying, pulverize and cross 100 mesh sieves, by the mixing of gained powder irradiation sterilization, obtaining composite bacterium powder, standby；
(3) Semen Lablab Album selected and clean after, roast, roast temperature 150 DEG C, 20 minutes time, be cooled to room temperature, after pulverizing cross 100 mesh sieves, obtain Semen Lablab Album powder；Coix seed and maize is selected and cleans post-drying, pulverizes together, and crosses after 100 mesh sieves and be mixed together uniformly with Semen Lablab Album powder；
(4) take the fleece-flower root, sealwort, Gorgon fruit, Buddha's hand ginseng, the Radix Astragali, the bighead atractylodes rhizome, wilsonii, dried orange peel and the tuber of pinellia, add the ethanol solution of 5 times of weight 75wt%, extract 2 hours at a temperature of 90 DEG C, extract twice, filter, in filter residue, add the water of 10 times of weight, boil, extract 1.5 hours, filter, merge No. 3 extracts and be concentrated to give medicinal extract, gained medicinal extract is spray-dried, and cross 100 mesh sieves, collect dry powder；
(5) composite bacterium powder that the GL-B that step (1) prepared, step (2) obtain, step (3) pulverize after material and the dry powder blend of step (4) uniform；
(6) auxiliary material that mixture step (5) obtained adds pharmaceutically prepares capsule, granule, pill, powder or tablet.
Embodiment 3
A kind of benefit gas tonifying spleen lucid ganoderma complex preparation, its raw material includes tri-components of A, B and C, and in terms of parts by weight, the formula composition of tri-components of A, B and C is as follows:
Component A:
Glossy ganoderma 36 parts, 12 parts of mushroom, grey mushroom (abalonelike) 7.5 parts and 6 parts of white fungus；
B component:
Coix seed 15 parts, Semen Lablab Album 6 parts and maize 7 parts；
Component C:
The fleece-flower root 15 parts, sealwort 12 parts, Gorgon fruit 12 parts, Buddha's hand join 5 parts, the Radix Astragali 10 parts, the bighead atractylodes rhizome 8 parts, wilsonii 11 parts, dried orange peel 4 parts and the tuber of pinellia 3.5 parts.
The preparation method of benefit gas tonifying spleen lucid ganoderma complex preparation as above, specifically includes following steps:
(1) preparation of GL-B: add in the water of 15 times of quality after glossy ganoderma is pulverized, keep 90 minutes after boiling, filter, the ethanol of 95wt% is added in gained filter residue, and extract 3 hours at 90 DEG C, filter to obtain glossy ganoderma slag, after being dried at 50 DEG C by glossy ganoderma slag and after ultramicro grinding, excessively 120 mesh sieves, obtain glossy ganoderma powder；The glossy ganoderma powder of gained is joined in the water that quality is glossy ganoderma powder 20 times, regulation pH is 4, add complex enzyme, the addition of complex enzyme is to carry out enzymolysis and extraction under the 1% of glossy ganoderma powder quality, stirring, and enzymolysis and extraction condition is: hydrolysis temperature is 50 DEG C, enzymolysis time is 90 minutes, described complex enzyme is Fungal Acid Protease and cellulase 1:3 in mass ratio mixing, and enzymolysis and extraction terminates rear centrifugation, takes supernatant and is enzyme-extracting solution；The daltonian film of gained enzyme-extracting solution molecular cut off 13500 is carried out ultrafiltration, collects ultrafiltration permeate；Gained ultrafiltration permeate is concentrated in vacuo to the 30% of original volume, obtains concentrate；Being joined by gained concentrate in the ethanol of 95wt%, after mixing, ethanol mass percent becomes 60wt%, stands 7h, centrifugal segregation supernatant, collects precipitation, obtains GL-B after freeze-drying；
(2) by after clean to mushroom, grey mushroom (abalonelike) and white fungus drying, pulverize and cross 90 mesh sieves, by the mixing of gained powder irradiation sterilization, obtaining composite bacterium powder, standby；
(3) Semen Lablab Album selected and clean after, roast, roast temperature 150 DEG C, 20 minutes time, be cooled to room temperature, after pulverizing cross 100 mesh sieves, obtain Semen Lablab Album powder；Coix seed and maize is selected and cleans post-drying, pulverizes together, and crosses after 100 mesh sieves and be mixed together uniformly with Semen Lablab Album powder；
(4) take the fleece-flower root, sealwort, Gorgon fruit, Buddha's hand ginseng, the Radix Astragali, the bighead atractylodes rhizome, wilsonii, dried orange peel and the tuber of pinellia, add the ethanol solution of 5 times of weight 75wt%, extract 2 hours at a temperature of 90 DEG C, extract twice, filter, in filter residue, add the water of 10 times of weight, boil, extract 1.5 hours, filter, merge No. 3 extracts and be concentrated to give medicinal extract, gained medicinal extract is spray-dried, and cross 100 mesh sieves, collect dry powder；
(5) composite bacterium powder that the GL-B that step (1) prepared, step (2) obtain, step (3) pulverize after material and the dry powder blend of step (4) uniform；
(6) auxiliary material that mixture step (5) obtained adds pharmaceutically prepares capsule, granule, pill, powder or tablet.
Embodiment 4
A kind of benefit gas tonifying spleen lucid ganoderma complex preparation, its raw material includes tri-components of A, B and C, and in terms of parts by weight, the formula composition of tri-components of A, B and C is as follows:
Component A:
Glossy ganoderma 37 parts, 11 parts of mushroom, grey mushroom (abalonelike) 8 parts and 6 parts of white fungus；
B component:
Coix seed 15 parts, Semen Lablab Album 7 parts and maize 6 parts；
Component C:
The fleece-flower root 16 parts, sealwort 10 parts, Gorgon fruit 12.5 parts, Buddha's hand join 6.8 parts, the Radix Astragali 11 parts, the bighead atractylodes rhizome 9 parts, wilsonii 10 parts, dried orange peel 3 parts and the tuber of pinellia 4 parts.
The preparation method of benefit gas tonifying spleen lucid ganoderma complex preparation as above, specifically includes following steps:
(1) preparation of GL-B: add in the water of 15 times of quality after glossy ganoderma is pulverized, keep 90 minutes after boiling, filter, the ethanol of 95wt% is added in gained filter residue, and extract 3 hours at 90 DEG C, filter to obtain glossy ganoderma slag, after being dried at 50 DEG C by glossy ganoderma slag and after ultramicro grinding, excessively 120 mesh sieves, obtain glossy ganoderma powder；The glossy ganoderma powder of gained is joined in the water that quality is glossy ganoderma powder 20 times, regulation pH is 4, add complex enzyme, the addition of complex enzyme is to carry out enzymolysis and extraction under the 1% of glossy ganoderma powder quality, stirring, and enzymolysis and extraction condition is: hydrolysis temperature is 48 DEG C, enzymolysis time is 80 minutes, described complex enzyme is Fungal Acid Protease and cellulase 1:3 in mass ratio mixing, and enzymolysis and extraction terminates rear centrifugation, takes supernatant and is enzyme-extracting solution；The daltonian film of gained enzyme-extracting solution molecular cut off 14000 is carried out ultrafiltration, collects ultrafiltration permeate；Gained ultrafiltration permeate is concentrated in vacuo to the 30% of original volume, obtains concentrate；Being joined by gained concentrate in the ethanol of 95wt%, after mixing, ethanol mass percent becomes 60wt%, stands 6.5h, centrifugal segregation supernatant, collects precipitation, obtains GL-B after freeze-drying；
(2) by after clean to mushroom, grey mushroom (abalonelike) and white fungus drying, pulverize and cross 100 mesh sieves, by the mixing of gained powder irradiation sterilization, obtaining composite bacterium powder, standby；
(3) Semen Lablab Album selected and clean after, roast, roast temperature 150 DEG C, 20 minutes time, be cooled to room temperature, after pulverizing cross 100 mesh sieves, obtain Semen Lablab Album powder；Coix seed and maize is selected and cleans post-drying, pulverizes together, and crosses after 100 mesh sieves and be mixed together uniformly with Semen Lablab Album powder；
(4) take the fleece-flower root, sealwort, Gorgon fruit, Buddha's hand ginseng, the Radix Astragali, the bighead atractylodes rhizome, wilsonii, dried orange peel and the tuber of pinellia, add the ethanol solution of 5 times of weight 75wt%, extract 2 hours at a temperature of 90 DEG C, extract twice, filter, in filter residue, add the water of 10 times of weight, boil, extract 1.5 hours, filter, merge No. 3 extracts and be concentrated to give medicinal extract, gained medicinal extract is spray-dried, and cross 100 mesh sieves, collect dry powder；
(5) composite bacterium powder that the GL-B that step (1) prepared, step (2) obtain, step (3) pulverize after material and the dry powder blend of step (4) uniform；
(6) auxiliary material that mixture step (5) obtained adds pharmaceutically prepares capsule, granule, pill, powder or tablet.
The foregoing is only presently preferred embodiments of the present invention, all impartial changes done according to scope of the present invention patent and modification, all should belong to the covering scope of the present invention.
Claims (3)
1. a beneficial gas tonifying spleen lucid ganoderma complex preparation, it is characterised in that: the raw material of described compound preparation includes tri-components of A, B and C, and in terms of parts by weight, the formula composition of tri-components of A, B and C is as follows:
Component A:
Glossy ganoderma 35 ~ 38 parts, 10 ~ 12 parts of mushroom, grey mushroom (abalonelike) 6 ~ 9 parts and 6 ~ 8 parts of white fungus；
B component:
Coix seed 13 ~ 16 parts, Semen Lablab Album 5 ~ 8 parts and maize 5 ~ 8 parts；
Component C:
The fleece-flower root 10 ~ 20 parts, sealwort 9 ~ 15 parts, Gorgon fruit 10 ~ 15 parts, Buddha's hand join 3 ~ 9 parts, the Radix Astragali 9 ~ 15 parts, the bighead atractylodes rhizome 6 ~ 12 parts, wilsonii 9 ~ 13 parts, dried orange peel 3 ~ 5 parts and the tuber of pinellia 3 ~ 4 parts.
A kind of benefit gas tonifying spleen lucid ganoderma complex preparation the most according to claim 1, it is characterised in that: described compound preparation includes tri-components of A, B and C, and in terms of parts by weight, the formula composition of tri-components of A, B and C is as follows:
Component A:
Glossy ganoderma 36 parts, 12 parts of mushroom, grey mushroom (abalonelike) 7.5 parts and 6 parts of white fungus；
B component:
Coix seed 15 parts, Semen Lablab Album 6 parts and maize 7 parts；
Component C:
The fleece-flower root 15 parts, sealwort 12 parts, Gorgon fruit 12 parts, Buddha's hand join 5 parts, the Radix Astragali 10 parts, the bighead atractylodes rhizome 8 parts, wilsonii 11 parts, dried orange peel 4 parts and the tuber of pinellia 3.5 parts.
3. the beneficial gas tonifying spleen lucid ganoderma complex preparation prepared as described in claim 1-2, it is characterised in that: specifically include following steps:
(1) preparation of GL-B: add in the water of 15 times of quality after glossy ganoderma is pulverized, keep 90 minutes after boiling, filter, the ethanol of 95wt% is added in gained filter residue, and extract 3 hours at 90 DEG C, filter to obtain glossy ganoderma slag, after being dried at 50 DEG C by glossy ganoderma slag and after ultramicro grinding, excessively 120 mesh sieves, obtain glossy ganoderma powder；The glossy ganoderma powder of gained is joined in the water that quality is glossy ganoderma powder 20 times, regulation pH is 4, add complex enzyme, the addition of complex enzyme is to carry out enzymolysis and extraction under the 1% of glossy ganoderma powder quality, stirring, and enzymolysis and extraction condition is: hydrolysis temperature is 45 ~ 55 DEG C, enzymolysis time is 60 ~ 120 minutes, described complex enzyme is Fungal Acid Protease and cellulase 1:3 in mass ratio mixing, and enzymolysis and extraction terminates rear centrifugation, takes supernatant and is enzyme-extracting solution；The daltonian film of gained enzyme-extracting solution molecular cut off 12000 ~ 15000 is carried out ultrafiltration, collects ultrafiltration permeate；Gained ultrafiltration permeate is concentrated in vacuo to the 30% of original volume, obtains concentrate；Being joined by gained concentrate in the ethanol of 95wt%, after mixing, ethanol mass percent becomes 60wt%, stands 6 ~ 8h, centrifugal segregation supernatant, collects precipitation, obtains GL-B after freeze-drying；
(2) by after clean to mushroom, grey mushroom (abalonelike) and white fungus drying, pulverize and cross 80 ~ 100 mesh sieves, by the mixing of gained powder irradiation sterilization, obtaining composite bacterium powder, standby；
(3) Semen Lablab Album selected and clean after, roast, roast temperature 150 DEG C, 20 minutes time, be cooled to room temperature, after pulverizing cross 100 mesh sieves, obtain Semen Lablab Album powder；Coix seed and maize is selected and cleans post-drying, pulverizes together, and crosses after 100 mesh sieves and be mixed together uniformly with Semen Lablab Album powder；
(4) take the fleece-flower root, sealwort, Gorgon fruit, Buddha's hand ginseng, the Radix Astragali, the bighead atractylodes rhizome, wilsonii, dried orange peel and the tuber of pinellia, add the ethanol solution of 5 times of weight 75wt%, extract 2 hours at a temperature of 90 DEG C, extract twice, filter, in filter residue, add the water of 10 times of weight, boil, extract 1.5 hours, filter, merge No. 3 extracts and be concentrated to give medicinal extract, gained medicinal extract is spray-dried, and cross 100 mesh sieves, collect dry powder；
(5) composite bacterium powder that the GL-B that step (1) prepared, step (2) obtain, step (3) pulverize after material and the dry powder blend of step (4) uniform；
(6) auxiliary material that mixture step (5) obtained adds pharmaceutically prepares capsule, granule, pill, powder or tablet.
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