CN105853981A - Traditional Chinese medicine for treating cardiovascular and cerebrovascular diseases and preparation method of traditional Chinese medicine - Google Patents

Traditional Chinese medicine for treating cardiovascular and cerebrovascular diseases and preparation method of traditional Chinese medicine Download PDF

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CN105853981A
CN105853981A CN201610359662.7A CN201610359662A CN105853981A CN 105853981 A CN105853981 A CN 105853981A CN 201610359662 A CN201610359662 A CN 201610359662A CN 105853981 A CN105853981 A CN 105853981A
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radix
chinese medicine
rhizoma
treating cardiovascular
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钟晓鸣
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • A61K35/644Beeswax; Propolis; Royal jelly; Honey
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/16Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233Bupleurum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/27Asclepiadaceae (Milkweed family), e.g. hoya
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/346Platycodon
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/536Prunella or Brunella (selfheal)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/638Ligustrum, e.g. Chinese privet
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/82Theaceae (Tea family), e.g. camellia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
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    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

Abstract

The invention discloses a traditional Chinese medicine for treating cardiovascular and cerebrovascular diseases and a preparation method of the traditional Chinese medicine. The traditional Chinese medicine is prepared from, by weight, 20-30 parts of rhizoma atractylodis macrocephalae, 5-15 parts of folium ginkgo, 15-25 parts of Rhizoma Polygoni Cuspidati, 10-25 parts of tea tree root, 10-18 parts of ligustrum lucidum ait, 10-30 parts of salviae miltiorrhizae, 5-15 parts of achyranthes bidentata, 8-16 parts of Prunella vulgaris L, 12-20 parts of fructus lycii, 8-20 parts of radix bupleuri, 5-10 parts of ginger, 10-15 parts of coptidis rhizoma, 15-30 parts of radix platycodi, 3-9 parts of pseudo-ginseng, 10-16 parts of radix cynanchi bungei, 3-9 parts of cornu bubali and 20-45 parts of honey. The heart, qi, blood and energy of human bodies can be comprehensively conditioned, twelve main and collateral channels are dredged, effective components of the medicine rapidly enter blood to circulate, blood fat is effectively reduced, blood viscosity is reduced, micro-circulation of human bodies is improved, and cardiovascular and cerebrovascular diseases such as coronary heart disease, stenocardia and cerebral thrombosis are effectively treated; the traditional Chinese medicine is simple in preparation method, short in technological process, small in consumption, short in treatment course, rapid in effect, convenient to take, capable of preventing people from relapse, free of toxic and side effects and capable of greatly relieving pains and economic burdens of patients.

Description

A kind of Chinese medicine treating cardiovascular and cerebrovascular disease and preparation method thereof
Technical field
Technical field controlled by the Chinese medicine that the present invention relates to treat cardiovascular and cerebrovascular disease, particularly relates to a kind of Chinese medicine treating cardiovascular and cerebrovascular disease and preparation method thereof.
Background technology
Along with growth in the living standard and the change of rhythm of life, modern is due to long-time lipid the most in the diet too much and alcohols these Bad Eating Habit such as too much;Meanwhile, the most reasonably motion does not promotes lipid and the metabolism of alcohols, causes internal lipid and alcohols material gradually to increase;Adding with advancing age, various bodily tissues are the most aging, and cardiovascular and cerebrovascular vessel are particularly evident;And then making arteriosclerosis, thrombosis, the sickness rate of the cardiovascular and cerebrovascular disease such as coronary heart disease, hypertension, cerebral infarction substantially increases.
Cardiovascular and cerebrovascular disease is the general designation of cardiovascular and cerebrovascular disease, refers to the ischemic or hemorrhage occurred due to hyperlipemia, blood are sticky, atherosclerosis, hypertension etc. are caused heart, brain and body tissue.Cardiovascular and cerebrovascular disease is a kind of serious threat mankind, the commonly encountered diseases of particularly more than 50 years old middle-aged and elderly people health, there is high prevalence, high disability rate and the feature of high mortality, even if applying most advanced, perfect treatment means, the cerebrovas-cularaccident survivor life that still can have more than 50% can not be taken care of oneself completely, the whole world is died from the number of cardiovascular and cerebrovascular disease every year and is up to 15,000,000 people, occupies the various cause of the death the first.
At present, method or the medicine for the treatment of cardiovascular and cerebrovascular disease are varied, surgical operation, such as bypass surgery, intervention operation, change vascular surgery etc.;Traditional western medicine, such as aspirin, beta-blocker, statins etc.;Health product, such as fish oil class, propolis, Oleum Bulbus Allii, Semen Ginkgo etc.;Common Chinese medicine, such as Drug Prepared from Insects, Chinese medicine and western medicine compound formulation, Chinese medicine preparation etc..Above Therapeutic Method be cardio-cerebral vascular disease patient frequently with treatment option, but surgical operation has, and risk is big, the shortcoming of somewhat expensive;Western medicine only has long-term taking to benefit, and the most easily rebounds, and side effect is big, and damage ratio renovascular to liver is more serious, even has serious untoward reaction;Health product Main Function is the effect of lubrication expansion blood vessel, only serves the effect of auxiliary, it is impossible to from basic treatment;Treatment by Chinese herbs has advantages such as preparation technology is simple, with low cost, have no side effect, the research emphasis of the specific drug for the treatment of cardiovascular and cerebrovascular disease is always work of Chinese medicine person.
Summary of the invention
The technical problem existed based on background technology, the present invention proposes a kind of Chinese medicine treating cardiovascular and cerebrovascular disease and preparation method thereof.
A kind of Chinese medicine treating cardiovascular and cerebrovascular disease that the present invention proposes, including the raw material of following weight portion: Rhizoma Atractylodis Macrocephalae 20-30 part, Folium Ginkgo 5-15 part, Rhizoma Polygoni Cuspidati 15-25 part, Radix Camelliae sinensis 10-25 part, Fructus Ligustri Lucidi 10-18 part, Radix Salviae Miltiorrhizae 10-30 part, Radix Achyranthis Bidentatae 5-15 part, Spica Prunellae 8-16 part, Fructus Lycii 12-20 part, Radix Bupleuri 8-20 part, Rhizoma Zingiberis Recens 5-10 part, Rhizoma Coptidis 10-15 part, Radix Platycodonis 15-30 part, Radix Notoginseng 3-9 part, Radix Cynanchi Auriculati 10-16 part, Cornu Bubali 3-9 part, Mel 20-45 part.
Preferably, including the raw material of following weight portion: Rhizoma Atractylodis Macrocephalae 23-28 part, Folium Ginkgo 7-13 part, Rhizoma Polygoni Cuspidati 17-21 part, Radix Camelliae sinensis 12-22 part, Fructus Ligustri Lucidi 11-15 part, Radix Salviae Miltiorrhizae 15-26 part, Radix Achyranthis Bidentatae 7-13 part, Spica Prunellae 10-15 part, Fructus Lycii 14-19 part, Radix Bupleuri 10-17 part, Rhizoma Zingiberis Recens 6-8 part, Rhizoma Coptidis 11-14 part, Radix Platycodonis 18-27 part, Radix Notoginseng 4-8 part, Radix Cynanchi Auriculati 11-14 part, Cornu Bubali 5-8 part, Mel 24-43 part.
Preferably, including the raw material of following weight portion: the Rhizoma Atractylodis Macrocephalae 25 parts, Folium Ginkgo 10 parts, Rhizoma Polygoni Cuspidati 19 parts, Radix Camelliae sinensis 17 parts, Fructus Ligustri Lucidi 12 parts, Radix Salviae Miltiorrhizae 22 parts, Radix Achyranthis Bidentatae 10 parts, Spica Prunellae 12 parts, Fructus Lycii 16 parts, Radix Bupleuri 13 parts, 7 parts of Rhizoma Zingiberis Recens, Rhizoma Coptidis 12 parts, Radix Platycodonis 23 parts, Radix Notoginseng 6 parts, Radix Cynanchi Auriculati 13 parts, Cornu Bubali 6 parts, Mel 37 parts.
Preferably, the described Rhizoma Atractylodis Macrocephalae, Folium Ginkgo, Rhizoma Polygoni Cuspidati, Radix Camelliae sinensis, the weight ratio of Fructus Ligustri Lucidi are 24-29:6-13:17-23:13-22:11-16.
Preferably, described Radix Salviae Miltiorrhizae, Radix Achyranthis Bidentatae, Spica Prunellae, Fructus Lycii, Radix Bupleuri, Rhizoma Coptidis, the weight ratio of Radix Platycodonis are 12-25:6-11:9-13:14-18:11-17:11-14:18-26.
Preferably, described Mel uses Flos Sophorae Mel.
Preferably, its preparation method comprises the following steps:
S1, weighs Cornu Bubali according to certain weight portion, boiling 3-5 hour;
S2, Rhizoma Polygoni Cuspidati, Radix Camelliae sinensis, Fructus Ligustri Lucidi, Radix Salviae Miltiorrhizae, Radix Achyranthis Bidentatae, Fructus Lycii, Radix Bupleuri, Rhizoma Zingiberis Recens, Radix Notoginseng, Radix Cynanchi Auriculati is weighed according to deal proportioning, the stirring of Radix Notoginseng, Fructus Ligustri Lucidi and Fructus Lycii grinding rod is smashed to pieces, be sequentially placed into Rhizoma Polygoni Cuspidati again, Radix Camelliae sinensis, Radix Salviae Miltiorrhizae, Radix Achyranthis Bidentatae, Radix Bupleuri, Rhizoma Zingiberis Recens, Radix Cynanchi Auriculati mix, put into appropriate water to decoct, continue 30-55min, obtain mixture A;
S3, weighs the Rhizoma Atractylodis Macrocephalae, Folium Ginkgo, Spica Prunellae, Rhizoma Coptidis, the pulverizing of Radix Platycodonis pulverizer according to deal proportioning, obtains mixture B, put in cooker, then in cooker, add mixture A, and add appropriate water, persistently decoct 40-60min, obtain mixture C;
S4, mixes the Cornu Bubali in mixture C and S1, adds appropriate Mel the most again, is sufficiently stirred for 10-30min, i.e. can get a kind of Chinese medicine treating cardiovascular and cerebrovascular disease.
Raw material in above-mentioned Chinese medicine:
The Rhizoma Atractylodis Macrocephalae, bitter in the mouth, sweet, warm in nature.Returning spleen, stomach warp, function cures mainly: invigorating the spleen and benefiting QI, dampness diuretic, and hidroschesis is antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.Rhizoma Atractylodis Macrocephalae spleen invigorating, stomach function regulating, antiabortive.For insufficiency of the spleen lack of appetite, loose stool of having loose bowels, frequent fetal movement;Radix Camelliae sinensis is bitter;Cool.GUIXIN;Kidney channel, cures mainly: heart disease;Edema;Hepatitis;Dysmenorrhea;Sore swollen toxin;Aphtha;Soup fire is burnt;Herpes zoster;Psoriasis;Fructus Ligustri Lucidi, sweet, bitter, cold.Return liver, kidney channel, cure mainly: have a dizzy spell, early whitening of beard and hair, blurring of vision, fever due to yin deficiency;Folium Ginkgo, sweet, bitter, puckery, flat, for obstruction of collaterals by blood stasis, obstruction of qi in the chest and cardialgia, apoplectic hemiplegia, cough and asthma due to lung deficiency, hyperlipemia, Rhizoma Polygoni Cuspidati, mildly bitter flavor, cold nature, for jaundice due to damp-heat, stranguria with turbid discharge, leukorrhagia, rheumatic arthralgia, carbuncle sore tumefacting virus, burn due to hot liquid or fire, amenorrhea, lump in the abdomen, instep beats damage, cough due to lung-heat;Radix Salviae Miltiorrhizae, bitter in the mouth, it is slightly cold, for obstruction of qi in the chest and cardialgia, gastral cavity abdomen hypochondriac pain, the accumulation of abdominal mass abdominal mass, pyretic arthralgia pain, dysphoria and insomnia, menoxenia, dysmenorrhea amenorrhea, skin infection swells and ache;Radix Achyranthis Bidentatae, picric acid, flat, effect: promoting blood circulation to remove blood stasis, damp eliminating diuresis, heat-clearing and toxic substances removing.Control gonorrhea, hematuria, women's amenorrhea, lump in the abdomen, rheumatic arthritis, tinea pedis, edema, dysentery, malaria, diphtheria, carbuncle, traumatic injury;Spica Prunellae, pungent, bitter, cold.Return liver, gallbladder meridian, there is clearing away heat-fire, improving eyesight, the function of mass dissipating and swelling eliminating;Fructus Lycii, sweet, flat, return liver, kidney channel, for syndrome of yin deficiency of liver and kidney The sweet flat matter of this product is moistened, and flat invigorating the liver and kidney has strengthening by means of tonics effect, all cards of all hepatic and renal YIN deficiency all can apply;Radix Bupleuri, acrid in the mouth, hardship, cold nature, return liver, gallbladder, lung meridian, for cold, fever, alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia, uterine prolapse, proctoptosis;Rhizoma Zingiberis Recens, property is pungent cool, controls skin edema, the row severe edema due to hypofunction of the spleen;The pungent temperature of Rhizoma Zingiberis Recens juice, pungent scattered cold syndrome of the stomach strength is strong, is used for vomiting;The pungent temperature of Rhizoma Zingiberis, warming middle-JIAO is instigated cold, and recuperating depleted YANG is promoted blood circulation, and warming the spleen strength of trembling with fear is big, and Rhizoma Zingiberis Preparatum acrid in the mouth hardship does not walk table in walking, the temperature part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels is cold;Carbonized Rhizoma Zingiberis (processed) is warm in nature, and relatively homoiothermy divides cold;Roast Rhizoma Zingiberis Recens hardship temperature, relatively warming intestines and stomach is cold.Pungent and the scattered temperature of Rhizoma Zingiberis Recens, strengthening the spleen stomach, kind warming middle-JIAO to send down the adverse QI preventing or arresting vomiting, dehumidify the painful abdominal mass that disappears, and eliminating phlegm and stopping cough, with stopping nausea and vomiting by lowering the adverse flow of QI as length;Rhizoma Coptidis, heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomitting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood tells nosebleed, conjunctival congestion, toothache, quenches one's thirst, carbuncle furuncle;External treatment eczema, eczema, auditory meatus is suppurated.It is burning hot that Rhizoma Coptidis (processed with wine) is apt to the clear part of the body cavity above the diaphragm housing the heart and lungs.For conjunctival congestion, aphtha.Prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice clearing stomach stomach function regulating preventing or arresting vomiting.Tying mutually for cold and heat, damp and hot middle resistance, feeling of fullness is vomitted.Cornel Rhizoma Coptidis soothing liver-QI stomach function regulating preventing or arresting vomiting.For incoordination between the liver and stomach, vomit acid regurgitation;Radix Platycodonis, function cures mainly: lung qi dispersing, and sore-throat relieving eliminates the phlegm, evacuation of pus.For cough with copious phlegm, uncomfortable in chest not smooth, pharyngalgia, hoarseness, lung abscess vomiting pus, skin infection pus becomes and does not bursts;Radix Notoginseng, hardship sweet, micro-, temperature, return liver, stomach warp, be used for spitting blood, spit blood, epistaxis, have blood in stool, metrorrhagia, traumatic hemorrhage, chest and abdomen twinge, tumbling and swelling;Radix Cynanchi Auriculati, bitter but sweet flavor is puckery, and slightly warm in nature is nontoxic, has nourishing the liver and kidney, strengthening body, nourishes blood and enrich blood, crow palpus hair color, restrains vital essence, promoting tissue regeneration and ulcer healing, effect of loosening bowel to relieve constipation;Cornu Bubali, has heat clearing away, removing heat from blood, arresting convulsion, removing toxic substances.Cure the wound the cold pestilence pathogenic heat attacking blood system in febrile diseases, mania and irritation, irritated, delirium, macule, and jaundice is spitted blood, epistaxis, hematochezia, effect of swollen ulcer drug;Flos Sophorae Mel, property is refrigerant, there is the diuresis of drying of Flos Sophorae, effect of cooling blood for hemostasis, the normal resistivity of blood capillary can be kept, there is vasodilator, improve blood circulation, prevent sclerosis of blood vessels, reduce the effect such as blood fat and blood pressure, and for prevention of stroke, also have effect that heat clearing away invigorating middle warmer, removing toxic substances are moisturized simultaneously.Relatively it is applicable to the edible health of chronic and cardiovascular patient, is especially suitable for old people.
Raw material in the present invention, covers the whole systems such as the root of botanical herbs, footpath, flower and fruit, has given full play to characteristic property and effect of each raw material self, taken into account complementary action each other;Compatibility is the most suitable, drug effect complements each other, the heart, gas, blood and the row conditioning comprehensively that progresses greatly to human body, get through the twelve channels and collaterals of whole body, the effective ingredient making medicine quickly enters blood circulation, blood fat reducing effectively, the viscosity of reduction blood, improve the microcirculation of human body, effectively treat the cardiovascular and cerebrovascular disease such as coronary heart diseases and angina pectoris, cerebral thrombosis;Its preparation method is simple, and technological process is short, and consumption is few, short treating period, instant effect, taking convenience, without recurrence, has no side effect, significantly reduces misery and the financial burden of patient.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is explained orally further.
Embodiment one
A kind of probiotic feed improving growth of meat chicken immune performance that the present embodiment proposes, including the raw material of following weight portion: the Rhizoma Atractylodis Macrocephalae 22 parts, Folium Ginkgo 6 parts, Rhizoma Polygoni Cuspidati 17 parts, Radix Camelliae sinensis 13 parts, Fructus Ligustri Lucidi 11 parts, Radix Salviae Miltiorrhizae 14 parts, Radix Achyranthis Bidentatae 7 parts, Spica Prunellae 10 parts, Fructus Lycii 13 parts, Radix Bupleuri 11 parts, 6 parts of Rhizoma Zingiberis Recens, Rhizoma Coptidis 11 parts, Radix Platycodonis 17 parts, Radix Notoginseng 4 parts, Radix Cynanchi Auriculati 11 parts, Cornu Bubali 4 parts, Mel 24 parts.
Its preparation method comprises the following steps:
S1, weighs Cornu Bubali, boiling 3 hours according to certain weight portion;
S2, Rhizoma Polygoni Cuspidati, Radix Camelliae sinensis, Fructus Ligustri Lucidi, Radix Salviae Miltiorrhizae, Radix Achyranthis Bidentatae, Fructus Lycii, Radix Bupleuri, Rhizoma Zingiberis Recens, Radix Notoginseng, Radix Cynanchi Auriculati is weighed according to deal proportioning, the stirring of Radix Notoginseng, Fructus Ligustri Lucidi and Fructus Lycii grinding rod is smashed to pieces, be sequentially placed into Rhizoma Polygoni Cuspidati again, Radix Camelliae sinensis, Radix Salviae Miltiorrhizae, Radix Achyranthis Bidentatae, Radix Bupleuri, Rhizoma Zingiberis Recens, Radix Cynanchi Auriculati mix, put into appropriate water to decoct, continue 30min, obtain mixture A;
S3, weighs the Rhizoma Atractylodis Macrocephalae, Folium Ginkgo, Spica Prunellae, Rhizoma Coptidis, the pulverizing of Radix Platycodonis pulverizer according to deal proportioning, obtains mixture B, put in cooker, then add mixture A in cooker, and add appropriate water, persistently decoct 40min, obtain mixture C;
S4, mixes the Cornu Bubali in mixture C and S1, adds appropriate Mel the most again, is sufficiently stirred for 10min, i.e. can get a kind of Chinese medicine treating cardiovascular and cerebrovascular disease.
Embodiment two
A kind of Chinese medicine treating cardiovascular and cerebrovascular disease that the present embodiment proposes and preparation method thereof, including the raw material of following weight portion: the Rhizoma Atractylodis Macrocephalae 24 parts, Rhizoma Polygoni Cuspidati 19 parts, Radix Camelliae sinensis 17 parts, Fructus Ligustri Lucidi 13 parts, Radix Salviae Miltiorrhizae 19 parts, Radix Achyranthis Bidentatae 10 parts, Fructus Lycii 15 parts, Radix Bupleuri 13 parts, 7 parts of Rhizoma Zingiberis Recens, Rhizoma Coptidis 13 parts, Radix Platycodonis 21 parts, Radix Notoginseng 6 parts, Radix Cynanchi Auriculati 12 parts, Cornu Bubali 6 parts, Mel 30 parts.
Its preparation method comprises the following steps:
S1, weighs Cornu Bubali, boiling 3.5 hours according to certain weight portion;
S2, Rhizoma Polygoni Cuspidati, Radix Camelliae sinensis, Fructus Ligustri Lucidi, Radix Salviae Miltiorrhizae, Radix Achyranthis Bidentatae, Fructus Lycii, Radix Bupleuri, Rhizoma Zingiberis Recens, Radix Notoginseng, Radix Cynanchi Auriculati is weighed according to deal proportioning, the stirring of Radix Notoginseng, Fructus Ligustri Lucidi and Fructus Lycii grinding rod is smashed to pieces, be sequentially placed into Rhizoma Polygoni Cuspidati again, Radix Camelliae sinensis, Radix Salviae Miltiorrhizae, Radix Achyranthis Bidentatae, Radix Bupleuri, Rhizoma Zingiberis Recens, Radix Cynanchi Auriculati mix, put into appropriate water to decoct, continue 35min, obtain mixture A;
S3, weighs the Rhizoma Atractylodis Macrocephalae, Rhizoma Coptidis, the pulverizing of Radix Platycodonis pulverizer according to deal proportioning, obtains mixture B, put in cooker, then add mixture A in cooker, and add appropriate water, persistently decoct 45min, obtain mixture C;
S4, mixes the Cornu Bubali in mixture C and S1, adds appropriate Mel the most again, is sufficiently stirred for 15min, i.e. can get a kind of Chinese medicine treating cardiovascular and cerebrovascular disease.
Embodiment three
A kind of Chinese medicine treating cardiovascular and cerebrovascular disease that the present embodiment proposes and preparation method thereof, including the raw material of following weight portion: the Rhizoma Atractylodis Macrocephalae 28 parts, Folium Ginkgo 13 parts, Rhizoma Polygoni Cuspidati 23 parts, Radix Camelliae sinensis 22 parts, Radix Salviae Miltiorrhizae 25 parts, Spica Prunellae 14 parts, Fructus Lycii 18 parts, Radix Bupleuri 17 parts, 9 parts of Rhizoma Zingiberis Recens, Rhizoma Coptidis 14 parts, Radix Platycodonis 26 parts, Radix Notoginseng 7 parts, Radix Cynanchi Auriculati 14 parts, Cornu Bubali 8 parts, Mel 40 parts.
Its preparation method comprises the following steps:
S1, weighs Cornu Bubali, boiling 4 hours according to certain weight portion;
S2, Rhizoma Polygoni Cuspidati, Radix Camelliae sinensis, Radix Salviae Miltiorrhizae, Fructus Lycii, Radix Bupleuri, Rhizoma Zingiberis Recens, Radix Notoginseng, Radix Cynanchi Auriculati is weighed according to deal proportioning, Radix Notoginseng and Fructus Lycii grinding rod are stirred and smashs to pieces, be sequentially placed into Rhizoma Polygoni Cuspidati again, Radix Camelliae sinensis, Radix Salviae Miltiorrhizae, Radix Bupleuri, Rhizoma Zingiberis Recens, Radix Cynanchi Auriculati mix, put into appropriate water to decoct, continue 45min, obtain mixture A;
S3, weighs the Rhizoma Atractylodis Macrocephalae, Folium Ginkgo, Spica Prunellae, Rhizoma Coptidis, the pulverizing of Radix Platycodonis pulverizer according to deal proportioning, obtains mixture B, put in cooker, then add mixture A in cooker, and add appropriate water, persistently decoct 50min, obtain mixture C;
S4, mixes the Cornu Bubali in mixture C and S1, adds appropriate Mel the most again, is sufficiently stirred for 20min, i.e. can get a kind of Chinese medicine treating cardiovascular and cerebrovascular disease.
Embodiment four
A kind of Chinese medicine treating cardiovascular and cerebrovascular disease that the present embodiment proposes and preparation method thereof, including the raw material of following weight portion: the Rhizoma Atractylodis Macrocephalae 30 parts, Folium Ginkgo 15 parts, Rhizoma Polygoni Cuspidati 25 parts, Radix Camelliae sinensis 25 parts, Fructus Ligustri Lucidi 18 parts, Radix Salviae Miltiorrhizae 30 parts, Radix Achyranthis Bidentatae 15 parts, Spica Prunellae 16 parts, Fructus Lycii 20 parts, Radix Bupleuri 20 parts, Radix Platycodonis 30 parts, Radix Notoginseng 9 parts, Radix Cynanchi Auriculati 16 parts, Cornu Bubali 9 parts, Mel 45 parts.
Its preparation method comprises the following steps:
S1, weighs Cornu Bubali, boiling 5 hours according to certain weight portion;
S2, Rhizoma Polygoni Cuspidati, Radix Camelliae sinensis, Fructus Ligustri Lucidi, Radix Salviae Miltiorrhizae, Radix Achyranthis Bidentatae, Fructus Lycii, Radix Bupleuri, Radix Notoginseng, Radix Cynanchi Auriculati is weighed according to deal proportioning, the stirring of Radix Notoginseng, Fructus Ligustri Lucidi and Fructus Lycii grinding rod is smashed to pieces, be sequentially placed into Rhizoma Polygoni Cuspidati again, Radix Camelliae sinensis, Radix Salviae Miltiorrhizae, Radix Achyranthis Bidentatae, Radix Bupleuri, Radix Cynanchi Auriculati mix, put into appropriate water to decoct, continue 55min, obtain mixture A;
S3, weighs the Rhizoma Atractylodis Macrocephalae, Folium Ginkgo, Spica Prunellae, the pulverizing of Radix Platycodonis pulverizer according to deal proportioning, obtains mixture B, put in cooker, then add mixture A in cooker, and add appropriate water, persistently decoct 60min, obtain mixture C;
S4, mixes the Cornu Bubali in mixture C and S1, adds appropriate Mel the most again, is sufficiently stirred for 30min, i.e. can get a kind of Chinese medicine treating cardiovascular and cerebrovascular disease.
The present invention is expanded on further below in conjunction with concrete test example, wherein, including the animal toxicity test of Chinese medicine of the present invention and old white mouse is tested in the thrombotic impact of body.
Animal toxicity test: the medicine pill of the present invention, repeatedly animal toxicity test has been repeated, when testing every time, take adult white mouse 60, male and female half and half, body weight 150-350g/ only, is divided into two groups, often group 30, one of which is overdose test group, another group is normal amount test group, and overdose test group consumption is 18-24g/kg, and normal amount test group consumption is 5-8g/kg, administering mode is to be mixed in the food of white mouse supply white mouse to eat, three times a day, take continuously one month, observe every day and be administered reaction;Test of many times all results show, two groups of white mouse spirit, activity, diet, excretion are the most normal;Cuing open inspection, naked eyes examine main inside internal organs, no abnormality seen;Therefore, this Chinese medicine is without bad toxic and side effects.
Old white mouse is in body thrombotic impact test: senile rat can self-assembling formation blood stasis body constitution, be easily formed thrombus in vivo.Young rat is not the most easily formed thrombosis.Therefore in test, with senile rat as positive control, with young rat as negative control, administration group includes four kinds of Chinese medicines of the embodiment of the present invention one to embodiment four and the Chinese medicine of certain commercially available treatment cardiovascular and cerebrovascular disease.
The selection of material: male rat;Younger group Mus 4-6 in the age month, body weight 200-300g;Old group Mus 22-28 in the age month, body weight 450-550g.
Experimental result is as shown in the table:
Group White mouse quantity Duration of congestion (min)
Embodiment one 20 17.35±1.13**
Embodiment two 20 17.23±1.25**
Embodiment three 20 17.83±1.18**
Embodiment four 20 17.39±1.26**
Commercially available Chinese drug-treated group 20 12.47±1.43*
Old positive controls 20 10.58±1.49
Young positive controls 20 17.41±1.75
Remarks: * *, compared with old positive controls, shows as pole significant difference;*, compared with old positive controls, significant difference is shown as.
The above; it is only the present invention preferably detailed description of the invention; but protection scope of the present invention is not limited thereto; any those familiar with the art is in the technical scope that the invention discloses; according to technical scheme and inventive concept equivalent or change in addition thereof, all should contain within protection scope of the present invention.

Claims (7)

1. the Chinese medicine treating cardiovascular and cerebrovascular disease, it is characterized in that, including the raw material of following weight portion: Rhizoma Atractylodis Macrocephalae 20-30 part, Folium Ginkgo 5-15 part, Rhizoma Polygoni Cuspidati 15-25 part, Radix Camelliae sinensis 10-25 part, Fructus Ligustri Lucidi 10-18 part, Radix Salviae Miltiorrhizae 10-30 part, Radix Achyranthis Bidentatae 5-15 part, Spica Prunellae 8-16 part, Fructus Lycii 12-20 part, Radix Bupleuri 8-20 part, Rhizoma Zingiberis Recens 5-10 part, Rhizoma Coptidis 10-15 part, Radix Platycodonis 15-30 part, Radix Notoginseng 3-9 part, Radix Cynanchi Auriculati 10-16 part, Cornu Bubali 3-9 part, Mel 20-45 part.
A kind of Chinese medicine treating cardiovascular and cerebrovascular disease the most according to claim 1, it is characterized in that, described Chinese medicine includes the raw material of following weight portion: Rhizoma Atractylodis Macrocephalae 23-28 part, Folium Ginkgo 7-13 part, Rhizoma Polygoni Cuspidati 17-21 part, Radix Camelliae sinensis 12-22 part, Fructus Ligustri Lucidi 11-15 part, Radix Salviae Miltiorrhizae 15-26 part, Radix Achyranthis Bidentatae 7-13 part, Spica Prunellae 10-15 part, Fructus Lycii 14-19 part, Radix Bupleuri 10-17 part, Rhizoma Zingiberis Recens 6-8 part, Rhizoma Coptidis 11-14 part, Radix Platycodonis 18-27 part, Radix Notoginseng 4-8 part, Radix Cynanchi Auriculati 11-14 part, Cornu Bubali 5-8 part, Mel 24-43 part.
A kind of Chinese medicine treating cardiovascular and cerebrovascular disease the most according to claim 1, it is characterized in that, described Chinese medicine includes the raw material of following weight portion: the Rhizoma Atractylodis Macrocephalae 25 parts, Folium Ginkgo 10 parts, Rhizoma Polygoni Cuspidati 19 parts, Radix Camelliae sinensis 17 parts, Fructus Ligustri Lucidi 12 parts, Radix Salviae Miltiorrhizae 22 parts, Radix Achyranthis Bidentatae 10 parts, Spica Prunellae 12 parts, Fructus Lycii 16 parts, Radix Bupleuri 13 parts, 7 parts of Rhizoma Zingiberis Recens, Rhizoma Coptidis 12 parts, Radix Platycodonis 23 parts, Radix Notoginseng 6 parts, Radix Cynanchi Auriculati 13 parts, Cornu Bubali 6 parts, Mel 37 parts.
A kind of Chinese medicine treating cardiovascular and cerebrovascular disease the most according to claim 1, it is characterised in that the described Rhizoma Atractylodis Macrocephalae, Folium Ginkgo, Rhizoma Polygoni Cuspidati, Radix Camelliae sinensis, the weight ratio of Fructus Ligustri Lucidi are 24-29:6-13:17-23:13-22:11-16.
A kind of Chinese medicine treating cardiovascular and cerebrovascular disease the most according to claim 1, it is characterized in that, described Radix Salviae Miltiorrhizae, Radix Achyranthis Bidentatae, Spica Prunellae, Fructus Lycii, Radix Bupleuri, Rhizoma Coptidis, the weight ratio of Radix Platycodonis are 12-25:6-11:9-13:14-18:11-17:11-14:18-26.
A kind of Chinese medicine treating cardiovascular and cerebrovascular disease the most according to claim 1, it is characterised in that described Mel uses Flos Sophorae Mel.
7. according to a kind of Chinese medicine treating cardiovascular and cerebrovascular disease described in any one of claim 1-6, it is characterised in that its preparation method comprises the following steps:
S1, weighs Cornu Bubali according to certain weight portion, boiling 3-5 hour;
S2, Rhizoma Polygoni Cuspidati, Radix Camelliae sinensis, Fructus Ligustri Lucidi, Radix Salviae Miltiorrhizae, Radix Achyranthis Bidentatae, Fructus Lycii, Radix Bupleuri, Rhizoma Zingiberis Recens, Radix Notoginseng, Radix Cynanchi Auriculati is weighed according to deal proportioning, the stirring of Radix Notoginseng, Fructus Ligustri Lucidi and Fructus Lycii grinding rod is smashed to pieces, be sequentially placed into Rhizoma Polygoni Cuspidati again, Radix Camelliae sinensis, Radix Salviae Miltiorrhizae, Radix Achyranthis Bidentatae, Radix Bupleuri, Rhizoma Zingiberis Recens, Radix Cynanchi Auriculati mix, put into appropriate water to decoct, continue 30-55min, obtain mixture A;
S3, weighs the Rhizoma Atractylodis Macrocephalae, Folium Ginkgo, Spica Prunellae, Rhizoma Coptidis, the pulverizing of Radix Platycodonis pulverizer according to deal proportioning, obtains mixture B, put in cooker, then in cooker, add mixture A, and add appropriate water, persistently decoct 40-60min, obtain mixture C;
S4, mixes the Cornu Bubali in mixture C and S1, adds appropriate Mel the most again, is sufficiently stirred for 10-30min, i.e. can get a kind of Chinese medicine treating cardiovascular and cerebrovascular disease.
CN201610359662.7A 2016-05-27 2016-05-27 Traditional Chinese medicine for treating cardiovascular and cerebrovascular diseases and preparation method of traditional Chinese medicine Pending CN105853981A (en)

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Application publication date: 20160817