CN105853620A

CN105853620A - Preparation for regulating and treating thyroid cancer of oncology department patient after operation and preparation method for preparation

Info

Publication number: CN105853620A
Application number: CN201610334021.6A
Authority: CN
Inventors: 不公告发明人
Original assignee: Individual
Current assignee: Individual
Priority date: 2016-05-19
Filing date: 2016-05-19
Publication date: 2016-08-17

Abstract

The invention discloses a preparation for regulating and treating thyroid cancer of an oncology department patient after an operation. The preparation is prepared from the following raw medicaments in parts by weight: 15 to 26 parts of typhonium giganteum, 6 to 18 parts of hylomecon japonica, 3 to 8 parts of solanum nigrum, 16 to 22 parts of lantana camara, 4 to 11 parts of longhairy antenoron herb, 3 to 6 parts of acacia catechu, 5 to 10 parts of cynanchum atratum, 20 to 24 parts of homonoia riparia lour, 7 to 12 parts of cuttlebone, 17 to 21 parts of vittaria flexuosa, 2 to 5 parts of raspberry, 5 to 9 parts of sonchus brachyotus, 18 to 22 parts of agave sisalana, and 6 to 10 parts of peanut branches and leaves. The excellent effects of the preparation are also expressed in that the medicaments can achieve the purposes of strengthening body resistance and eliminating evil by utilizing the functions of strengthening the body resistance, fostering root and enhancing or regulating body immunity aiming at body immunity reduction, qi and blood damage, insufficient anti-pathogenic energy and the like which are easily caused by the oncology department patient after the operation.

Description

The preparation of Oncology patients postoperative medical treatment thyroid cancer and preparation method

Technical field

The present invention relates to traditional Chinese medicine field, particularly relate to the preparation of a kind of Oncology patients postoperative medical treatment thyroid cancer And preparation method.

Background technology

Thyroid cancer is incidence malignant tumour more typically, accounts for the l-2% of whole body malignant tumour, common with women, it is seen that In any age bracket.At present, the incidence of disease of thyroid cancer is in the notable trend risen year by year.Thyroid cancer is divided into mamillary gland The polytypes such as cancer, filter blocking cancer, undifferentiated carcinoma, cephaloma.Early clinical manifestation is inconspicuous, many no conscious symptons, and neck swells Block is often asymmetry lump.Lump easily earlier generates pressure symptom, as with hoarseness, and unsmooth breath, dysphagia, Or the local pressure symptom such as tenderness, during jugular vein pressurized, may occur in which the signs such as Ipsilateral venous engorgement and facial edema.

The methods for the treatment of of thyroid cancer has operative treatment, radiotherapy, chemotherapy, endocrine therapy and Chinese medicine Deng.Most for the treatment of of thyroid carcinoma first-selection operations, and combine clinical concrete condition and carry out radiotherapy, chemotherapy, endocrine therapy Deng.Patient's prognosis is general, and the side reaction that local recurrence, DISTANT METASTASES IN and complication and western medical treatment bring all brings perhaps to patient The most painful.And thyroid cancer is postoperative, Huan Zheqi, blood, body fluid consume wound in a large number, occur more spiritlessness and weakness, spontaneous sweating, dry, Hoarseness, neck turgor be uncomfortable, two just symptoms such as imbalance.The most increasing evidence shows, postoperative Chinese medicine can To improve the bad reaction that operation itself brings；Improve immunity, accelerate patient postoperative rehabilitation；Alleviate oral thyroid element sheet Bad reaction；Soften thyroid cancer postoperative neck projection scar；Alleviate chemotherapy；Suppression thyroglobulin, reduces serum first Shape gland globulin levels, prevents and delays recurrence and the transfer etc. of thyroid cancer.

Application publication number CN 103705861 A(application number 201410004460.1) Chinese invention patent document public Open a kind of Chinese medicine improving thyroid cancer postoperative deficiency of qi and blood card, be made up of the bulk drug of following weight proportion: Radix Astragali 20- 30g, Radix Codonopsis 10-20g, bighead atractylodes rhizome 20-30g, Chinese yam 20-30g, Semen Lablab Album 20-30g, coix seed 20-30g, dried orange peel 10-15g, trifoliate orange Shell 15-20g, arillus longan 20-30g, prepared rhizome of rehmannia 15-25g, Radix Angelicae Sinensis 10-20g, root of herbaceous peony 20-30g, fleece-flower root 20-30g, deer horn glue 20-30g, donkey-hide gelatin 10-15g, fruit of Chinese wolfberry 15-20g, Herba Lycopi 15-20g, Rhizoma Sparganii 10-15g, curcuma zedoary 10-15g, excrementum pteropi 20-30g, Turmeric 20-30g, pangolin 10-15g, scorpio 6-10g, bulb of fritillary 10-20g and plantain seed 20-30g.Application publication number CN 105287944 A(application numbers 201510871277.6) Chinese invention patent document disclose a kind of for assisting treatment first The Chinese medicine composition of shape gland cancer, is made up of the raw material of following weight portion: slender acanthopanax ginseng 5-11 part, cordate houttuynia 7-13 part, rhodiola root 3- 9 parts, Radix Angelicae Sinensis 2-17 part, matrimony vine 3-9 part, radix bupleuri 5-15 part, adenophora tetraphylla 3-14 part, Radix Astragali 4-9 part, isoflavones 0.3-1.2 Part, phycocyanin 0.2-0.8 part, grape pip 0.5-3 part.Application publication number CN 104306796 A(application number 201410671279.6) Chinese invention patent document discloses a kind of Chinese drug-treated group improving thyroid cancer postoperative phlegm stagnation resistance card Compound, is made up of the Medicinal crude drug of following weight portion: fiveleaf akebia fruit 15-25 part, prepared RHIZOMA CYPERI with vinegar 11-19 part, China rose 7-11 part, half Summer 7-15 part, semen brassicae 13-20 part, radix ranunculi ternati 30-40 part, Chinese violet 11-20 part, leaf of bamboo 20-40 part, stir-fry rice sprout 15-21 Part, bighead atractylodes rhizome 7-15 part.

In a word, traditional Chinese medicine is to alleviating postsurgery symptoms, accelerating postoperative reparation aspect and achieve preferable curative effect, but there is also one A little problems: such as can not effectively prevent transfer and the diffusion of tumour, still need to improve further to the curative effect improving clinical symptoms.

Summary of the invention

For the deficiencies in the prior art, it is an object of the invention to provide one and prepare simply, conveniently take, safely and effectively The preparation of Oncology patients postoperative medical treatment thyroid cancer.Said preparation can effectively alleviate postoperative patient bad reaction, strengthens treatment effect Really.

The technical scheme is that

The preparation of Oncology patients postoperative medical treatment thyroid cancer, is prepared from by following bulk drugs, is weight portion: Typhonium giganteum 15-26, japanese hylomecon root 6-18, black nightshade 3-8, common lantana flower 16-22, desmodium 4-11, catechu 3-6, radix cynanchi atrati 5-10, littleleaf dogwood root 20- 24, cuttlebone 7-12, ribbed value 17-21, raspberry 2-5, sowthistle 5-9, sisal hemp 18-22, peanut branchlet and leaf 6-10.

Preferably in scheme, Typhonium giganteum 18-23, japanese hylomecon root 10-14, black nightshade 4-7, common lantana flower 18-20, desmodium 6-9, Catechu 4-5, radix cynanchi atrati 6-9, littleleaf dogwood root 21-23, cuttlebone 8.5-10.5, ribbed value 18-20, raspberry 3-4, sowthistle 6-8, sword Fiber crops 19-21, peanut branchlet and leaf 7-9.

More preferably, Typhonium giganteum 20.5, japanese hylomecon root 12, black nightshade 5.5, common lantana flower 19, desmodium 7.5, catechu 4.5, Radix cynanchi atrati 7.5, littleleaf dogwood root 22, cuttlebone 9.5, ribbed value 19, raspberry 3.5, sowthistle 7, sisal hemp 20, peanut branchlet and leaf 8.

The preparation method of the preparation pill of Oncology patients postoperative medical treatment thyroid cancer, step is as follows:

(1) black nightshade and sisal hemp being mixed, the vinegar immersion adding 0.26-0.42 times amount (preferably adds 0.30-0.38 times in 45-75 minute The vinegar of amount soaks 55-65 minute), take out, dry, standby；

(2) littleleaf dogwood root, ribbed value, radix cynanchi atrati and japanese hylomecon root mixing, the saline solution of spray 2%-5% (preferably sprays the food of 2.5%-4.5% Salt solution), to mix thoroughly, vexed 18-30 minute (the most vexed 22-26 minute), slow fire is fried to micro-yellow heat color, takes out, standby；

(3) taking cuttlebone to put in smokeless stove fire, slow fire is calcined to sallow, takes out, and the raw material after processing with step (1) is together ground into Fine powder, sieves, and obtains mixing fine powders, standby；

(4) Typhonium giganteum, common lantana flower, desmodium, raspberry, sowthistle and peanut branchlet and leaf are mixed, add the cold of 8-12 times amount Water (preferably adds the cold water of 9-11 times amount), soaks 2-4 hour (preferably soaking 2.5-3.5 hour), is subsequently adding step (2) and processes After raw material, slow fire boiling 45-65 minute (preferably slow fire boiling 50-60 minute), filter, filtrate reduced in volume becomes thick paste, standby With；

(5) catechu and step (3) gained mixing fine powders are together joined in above-mentioned thick paste, add other auxiliary material while stirring, Mixing, is processed into the pill of Phoenix Tree Seed size, to obtain final product.

The preparation method of the preparation pill of above-mentioned Oncology patients postoperative medical treatment thyroid cancer, preferred scheme is, step (3) mistake 80-140 mesh sieve (preferred 100-120 mesh sieve, mistake 110 mesh sieve more preferably excessively).

The preparation method of the preparation pill of above-mentioned Oncology patients postoperative medical treatment thyroid cancer, preferred scheme is, step (5) described auxiliary material be mass fraction be 8.2% sucrose fine and mass fraction be the sodium cellulose glycolate of 2.3%.

The preparation method of described tablet is:

(1) black nightshade and sisal hemp being mixed, the vinegar immersion adding 0.26-0.42 times amount (preferably adds 0.30-0.38 times in 45-75 minute The vinegar of amount soaks 55-65 minute), take out, standby；

(2) taking cuttlebone to put in smokeless stove fire, slow fire is calcined to sallow, takes out, and the saline solution spraying 5%-9% immediately (preferably sprays The saline solution of 6%-8%), let cool, standby；

(3) common lantana flower and peanut branchlet and leaf mixing, be placed in medicine cookeding pot, and moderate heat adds to be propagandized hotly to burnt brown, takes out, lets cool, standby With；

(4) by surplus stock medicine in 92-110 DEG C dry 1.5-2.5 hour (be preferable over 98-104 DEG C dry 1.8-2.2 hour), Taking out, the raw material after processing with step (1)-(3) is together ground into fine powder, crosses 100-140 mesh sieve and (preferably crosses 110-130 mesh Sieve), add auxiliary material, mixing, be pressed into tablet, to obtain final product.

The preparation method of the formulation tablet of above-mentioned Oncology patients postoperative medical treatment thyroid cancer, preferred scheme is, step (4) auxiliary material described in be mass fraction be 8.6% dextrin fine powder and mass fraction be the stearic acid of 3.2%.

The preparation method of described decoction is:

(1) taking cuttlebone to put in smokeless stove fire, slow fire is calcined to sallow, takes out, and the saline solution spraying 5%-9% immediately (preferably sprays The saline solution of 6%-8%), let cool, be ground into fine powder with catechu altogether, cross 160-200 mesh sieve (preferably crossing 170-190 mesh sieve), standby；

(2) radix cynanchi atrati, littleleaf dogwood root, japanese hylomecon root and Typhonium giganteum being mixed, be placed in extractor, the ethanol with concentration as 45%-75% is Solvent (preferably the ethanol with concentration as 55%-65% is as solvent), the amount of solvent be 6.5-8.5 times of described material quantity (the most molten The amount of agent is 7-8 times of described material quantity), refluxing extraction twice, the most each extraction (respectively extracts 25-in 20-40 minute preferably every time 35 minutes), merge twice extract, filter, filtrate recycling ethanol, standby；

(3) being placed in medicine pot by the bulk drug in addition to step (1) and (2), the cold water adding 10-14 times amount (preferably adds 11-13 times The cold water of amount), big fire is heated to boiling, turns little fire and decocts twice, and the most each decoction (respectively decocts 35-45 in 30-50 minute preferably every time Minute), merging twice decocting liquid, filter, filtrate mixes with step (2) gained filtrate, is evaporated to the 1/4 of original volume, obtains mixed Close herb liquid, standby；

(4) step (1) gained fine powder is joined in step (3) gained mixing herb liquid, mixing, sterile packaged, to obtain final product.

The preparation method of described thick paste agent is:

(2) taking cuttlebone to put in smokeless stove fire, slow fire is calcined to sallow, takes out, and the saline solution spraying 5%-9% immediately (preferably sprays The saline solution of 6%-8%), let cool, raw material and catechu after processing with step (1) are ground into fine powder altogether, cross 160-200 mesh sieve (preferably Cross 170-190 mesh sieve), standby；

(3) being placed in Chinese medicine extracting tank by the bulk drug in addition to step (1) and (2), with pure water as solvent, the amount of solvent is institute State 7.5-10.5 times 8.5-9.5 times of described material quantity (amount of preferred solvent be) of material quantity, refluxing extraction twice, respectively Extracting 32-50 minute (each extraction 38-44 minute preferably every time), merge twice extract, filter, filtrate decocting liquid is concentrated into 80 DEG C Relative density is the clear cream of 1.22-1.25, standby；

(4) step (2) gained fine powder is joined in above-mentioned clear cream, mixing, hot air sterilization, cooling, encapsulation, to obtain final product.

The preparation recipe science of Oncology patients of the present invention postoperative medical treatment thyroid cancer, preparation method is simple, taking convenience, Effect is notable.In addition, the excellent results of the present invention is also manifested by:

1, the tradition property of medicine is organically combined by the present invention with Chinese medicine modern pharmacology, drugs to form a prescription, promotes curative effect；Taking convenience, safety, Have no side effect；

2, medicine of the present invention easily causes Abwehrkraft des Koepers reduction, impaired, the positive unsaturated vapor of qi and blood etc. for postoperative thyroid cancer patients, Utilize traditional Chinese medical science righting reinforcing and enhancing or adjustment body's immunity, reach the purpose of strengthening vital QI to eliminate pathogenic factors；

3, medicine source of the present invention is easy to get, and medicinal material is with low cost, determined curative effect, has higher promotional value.

Detailed description of the invention

Describe technical scheme in detail below in conjunction with embodiment and experimental example, but protection domain is not limited to this.

The preparation of embodiment 1 Oncology patients postoperative medical treatment thyroid cancer, is prepared from by following bulk drugs, all attaches most importance to Amount part (600g/ part): Typhonium giganteum 15 parts, japanese hylomecon root 6 parts, black nightshade 3 parts, common lantana flower 16 parts, desmodium 4 parts, 3 parts of catechu, in vain Common vetch 5 parts, littleleaf dogwood root 20 parts, cuttlebone 7 parts, ribbed value 17 parts, raspberry 2 parts, sowthistle 5 parts, 18 parts of sisal hemp, peanut branchlet and leaf 6 parts.

The preparation method of the preparation pill of Oncology patients postoperative medical treatment thyroid cancer is:

(1) black nightshade and sisal hemp being mixed, the vinegar adding 0.26 times amount soaks 45 minutes, takes out, and dries, standby；

(2) littleleaf dogwood root, ribbed value, radix cynanchi atrati and japanese hylomecon root mixing, the saline solution of spray 2%, mix thoroughly, vexed 18 minutes, and slow fire is fried to micro- Yellow heat color, takes out, standby；

(3) taking cuttlebone to put in smokeless stove fire, slow fire is calcined to sallow, takes out, and the raw material after processing with step (1) is together ground into Fine powder, crosses 80 mesh sieves, obtains mixing fine powders, standby；

(4) Typhonium giganteum, common lantana flower, desmodium, raspberry, sowthistle and peanut branchlet and leaf are mixed, add the cold water of 8 times amount, Soaking 2 hours, be subsequently adding the raw material after step (2) processes, slow fire boiling 45 minutes, filter, filtrate reduced in volume becomes thick paste, Standby；

(5) catechu and step (3) gained mixing fine powders are together joined in above-mentioned thick paste, add other auxiliary material while stirring, Described auxiliary material be mass fraction be 8.2% sucrose fine and mass fraction be the sodium cellulose glycolate of 2.3%, mixing, processing Become the pill of Phoenix Tree Seed size, to obtain final product.

The instructions of taking of gained pill of the present invention is: three times a day, each 6-8 ball, and warm water takes, 20 days courses for the treatment of.

The preparation of embodiment 2 Oncology patients postoperative medical treatment thyroid cancer, is prepared from by following bulk drugs, all attaches most importance to Amount part (200g/ part): Typhonium giganteum 26 parts, japanese hylomecon root 18 parts, black nightshade 8 parts, common lantana flower 22 parts, desmodium 11 parts, 6 parts of catechu, Radix cynanchi atrati 10 parts, littleleaf dogwood root 24 parts, cuttlebone 12 parts, ribbed value 21 parts, raspberry 5 parts, sowthistle 9 parts, 22 parts of sisal hemp, peanut 10 parts of branches and leaves.

The preparation method of the formulation tablet of Oncology patients postoperative medical treatment thyroid cancer is:

(1) black nightshade and sisal hemp being mixed, the vinegar adding 0.34 times amount soaks 60 minutes, takes out, standby；

(2) taking cuttlebone to put in smokeless stove fire, slow fire is calcined to sallow, takes out, and the saline solution of spray 7%, lets cool immediately, standby；

(4) being dried 2 hours in 101 DEG C by surplus stock medicine, take out, the raw material after processing with step (1)-(3) is together ground into Fine powder, cross 120 mesh sieves, add auxiliary material, described auxiliary material be mass fraction be 8.6% dextrin fine powder and mass fraction be 3.2% Stearic acid, mixing, it is pressed into tablet, to obtain final product.

The instructions of taking of gained tablet of the present invention is: three times a day, each 4-6 sheet, and warm water takes, 20 days courses for the treatment of.

Model case: old XX, man, 31 years old, people from Tai'an.Patient is to our hospital on July 17th, 2013.Patient's readme: At the beginning of 2012 9 months, because of uncomfortable to local people's examination in hospital be diagnosed as left side thyroid cancer, after in November, 2012 at this Institute's row surgery excision, there is malaise symptoms in postoperative patient health, introduces to our hospital through many friends.Check: patient is uncomfortable in chest to suppress Gas, shortness of breath and fatigue, god is tired to become thin, appetite stimulator, and two is the most uncomfortable, and the dark violet few tongue of tongue nature, arteries and veins is the most puckery.Agree to through patient and family members, Take the formulation tablet of the present embodiment gained Oncology patients postoperative medical treatment thyroid cancer, instructions of taking: three times a day, each 4- 6, warm water takes, 20 days courses for the treatment of.After taking two courses for the treatment of, patient is conscious, and uncomfortable symptom substantially alleviates；Take four After the individual course for the treatment of, patients symptomatic and sign all disappear, and health, without any discomfort, is paid a return visit after half a year, without recurrence.

The preparation of embodiment 3 Oncology patients postoperative medical treatment thyroid cancer, is prepared from by following bulk drugs, all attaches most importance to Amount part (500g/ part): Typhonium giganteum 18 parts, japanese hylomecon root 10 parts, black nightshade 4 parts, common lantana flower 18 parts, desmodium 6 parts, 4 parts of catechu, in vain Common vetch 6 parts, littleleaf dogwood root 21 parts, cuttlebone 8.5 parts, ribbed value 18 parts, raspberry 3 parts, sowthistle 6 parts, 19 parts of sisal hemp, peanut branch 7 parts of leaf.

The preparation method of the preparation decoction of Oncology patients postoperative medical treatment thyroid cancer is:

(1) taking cuttlebone to put in smokeless stove fire, slow fire is calcined to sallow, takes out, and the saline solution of spray 7%, lets cool, with catechu immediately It is ground into fine powder altogether, crosses 180 mesh sieves, standby；

(2) radix cynanchi atrati, littleleaf dogwood root, japanese hylomecon root and Typhonium giganteum are mixed, be placed in extractor, with ethanol that concentration is 60% as solvent, The amount of solvent is 7.5 times of described material quantity, refluxing extraction twice, the most each extraction 30 minutes, merges twice extract, mistake Filter, filtrate recycling ethanol, standby；

(3) being placed in medicine pot by the bulk drug in addition to step (1) and (2), add the cold water of 12 times amount, big fire is heated to boiling, turns Little fire decocts twice, the most each decoction 40 minutes, merges twice decocting liquid, filters, and filtrate mixes with step (2) gained filtrate, subtracts Pressure is concentrated into the 1/4 of original volume, obtains mixing herb liquid, standby；

The instructions of taking of gained decoction of the present invention is: twice daily, each 120-150mL, and warm is taken, treatment in 20 days Journey.

The preparation of embodiment 4 Oncology patients postoperative medical treatment thyroid cancer, is prepared from by following bulk drugs, all attaches most importance to Amount part (300g/ part): Typhonium giganteum 23 parts, japanese hylomecon root 14 parts, black nightshade 7 parts, common lantana flower 20 parts, desmodium 9 parts, 5 parts of catechu, in vain Common vetch 9 parts, littleleaf dogwood root 23 parts, cuttlebone 10.5 parts, ribbed value 20 parts, raspberry 4 parts, sowthistle 8 parts, 21 parts of sisal hemp, peanut 9 parts of branches and leaves.

The preparation method of the preparation thick paste agent of Oncology patients postoperative medical treatment thyroid cancer is:

(1) black nightshade and sisal hemp being mixed, the vinegar adding 0.34 times amount soaks 60 minutes, takes out, and dries, standby；

(2) taking cuttlebone to put in smokeless stove fire, slow fire is calcined to sallow, takes out, and the saline solution of spray 7%, lets cool, with step immediately (1) raw material and catechu after processing are ground into fine powder altogether, cross 180 mesh sieves, standby；

(3) being placed in Chinese medicine extracting tank by the bulk drug in addition to step (1) and (2), with pure water as solvent, the amount of solvent is institute State material quantity 9 times, refluxing extraction twice, the most each extraction 41 minutes, merge twice extract, filter, filtrate decocting liquid concentrates To the clear cream that 80 DEG C of relative densities are 1.22-1.25, standby；

The instructions of taking of gained thick paste agent of the present invention is: three times a day, each 80-100g, and warm water is taken after mixing it with water, treatment in 20 days Journey.

The preparation of embodiment 5 Oncology patients postoperative medical treatment thyroid cancer, is prepared from by following bulk drugs, all attaches most importance to Amount part (400g/ part): Typhonium giganteum 20.5 parts, japanese hylomecon root 12 parts, black nightshade 5.5 parts, common lantana flower 19 parts, desmodium 7.5 parts, catechu 4.5 parts, radix cynanchi atrati 7.5 parts, littleleaf dogwood root 22 parts, cuttlebone 9.5 parts, ribbed value 19 parts, raspberry 3.5 parts, sowthistle 7 parts, sisal hemp 20 parts, peanut branchlet and leaf 8 parts.

(2) littleleaf dogwood root, ribbed value, radix cynanchi atrati and japanese hylomecon root mixing, the saline solution of spray 3.5%, mix thoroughly, vexed 24 minutes, and slow fire is fried extremely Micro-yellow heat color, takes out, standby；

(3) taking cuttlebone to put in smokeless stove fire, slow fire is calcined to sallow, takes out, and the raw material after processing with step (1) is together ground into Fine powder, crosses 110 mesh sieves, obtains mixing fine powders, standby；

(4) Typhonium giganteum, common lantana flower, desmodium, raspberry, sowthistle and peanut branchlet and leaf are mixed, add the cold water of 10 times amount, Soaking 3 hours, be subsequently adding the raw material after step (2) processes, slow fire boiling 55 minutes, filter, filtrate reduced in volume becomes thick paste, Standby；

Model case: Zhao XX, female, 52 years old, people from Heze.Patient is to our hospital on March 22nd, 2014.Patient's readme: Within 2013, find when routine physical examination that right neck has swollen thing projection, is diagnosed as thyroid cancer on inspection, carries out in September, 2013 Ocal resection, postsurgery symptoms progressively takes a turn for the better, and in 12 months, the discomforts such as palpitation, malaise occurs in patient.Upon somebody's introduction Come my institute and check treatment.Check: patient's palpitation, malaise, spontaneous sweating, One's spirits are drooping, dry mouth and throat, five is vexed Heat, has a dizzy spell, dysphagia, and gas uncomfortable in chest is suppressed, and body is become thin, and tongue is red, and tongue is few, and deep thready pulse is several；Heart kidney yin is caused for postoperative Chronic diseases marked by deficiency of vital energy shape.Agree to through patient and family members, take the preparation pill of the present embodiment gained Oncology patients postoperative medical treatment thyroid cancer, Instructions of taking: three times a day, each 6-8 ball, warm water takes, 20 days courses for the treatment of.After taking two courses for the treatment of, the conscious health of patient Malaise symptoms substantially alleviates；After taking four courses for the treatment of, patients symptomatic and sign all disappear, and health is without any discomfort, after half a year Pay a return visit, without recurrence.

Used by the present invention, the pharmacology of main Chinese medicine material is as follows:

Typhonium giganteum: Ji Yuan: for the herb of aroid Typhonium giganteum.Another name: rhizoma thyponii, milk male star the most attached, red, fiber crops taro The tuber of pinellia, wild, heart are the most attached.Nature and flavor: acrid, sweet, warm.Poisonous.Gui Jing: return stomach, Liver Channel.Function: eliminating dampness and eliminating phlegm, timid wind stops convulsion, Detoxicating and resolving a mass.It is applicable to the stagnant network of wind phlegm, facial paralysis, apoplexy phlegm Sheng, aphasia hemiplegia, lockjaw and cold-damp headache；External application is used In subcutaneous nodule scrofula, venomous snake bite.

Japanese hylomecon root: Ji Yuan: for the root of bloodroot japanese hylomecon root.Nature and flavor: " Shaanxi Chinese herbal medicine ": " bitter, property is put down." function Cure mainly: " Shaanxi Chinese herbal medicine ": " wines used as antirheumatic, stimulates the circulation of the blood and cause the muscles and joints to relax, and dissipates stagnation resolvation and swells, analgesic hemostatic.Treating rheumatic arthritis, internal lesion caused by overexertion, fall and beat Damage.”

Black nightshade: Ji Yuan: for Solanaceae nightshade black nightshade, with all herbal medicine.Nature and flavor: bitter, cold.Slightly poisonous.Function cures mainly: heat-clearing Removing toxic substances, inducing diuresis for removing edema.For cat fever, toothache, chronic bronchitis, dysentery, urinary infection, mastitis, leukorrhea, cancer Disease；Carbuncle furuncle furunculosis, pemphigus, snake bite are controlled in external application.

Common lantana flower: Ji Yuan: for the flower of dicotyledon medicine Verbenaceae lantana.Chemical analysis: containing volatile oil 0.07%.It is mainly composed of oxalene, alpha, gamma-terpinene, α, nopinene and cymol etc..The another glucoside look Han pattern Element.Nature and flavor: sweet light；Cool.Gui Jing: lung；Liver；Kidney channel.Function cures mainly: refreshing and detoxicating；Promoting blood circulation and hemostasis；Moisten the lung and relieve the cough；Solve hot summer weather.Main Tuberculosis is spitted blood；Summer-heat headache；Stomachache is vomited and diarrhoea；Pruritus vulvae；Eczema；Traumatic injury.

Desmodium: Ji Yuan: for herb or the whole herb with root of labiate blood circulation promoting pill.Pharmacological action: use desmodium decoction 20 grams (crude drug)/kilogram give rat oral gavage, have significant diuresis, continuous application then diuresis is gradually lowered.In anesthesia In the acute experiment of rabbit, with 10 grams (crude drugs)/kilogram gavage, also there is obvious diuresis.Nature and flavor: toil are cool.Gui Jing: Liver；Courage；Kidney；Bladder warp.Function cures mainly: heat-clearing, diuresis, antibechic, detumescence, removing toxic substances.Harness the Yellow River subcutaneous ulcer, oedema, vesical calculus, malaria, Lung carbuncle, cough, to spit blood, stranguria with turbid discharge, under band, arthralgia due to wind-dampness, infantile malnutrition, frightened epilepsy, carbuncle swells, sore tinea, eczema.

Catechu: Ji Yuan: this product is the going by branch, dry dry soft extracts of legume catechu.Gather winter skill, dry, remove Crust, is chopped to bulk, boiling, concentrates, be dried.Proterties: this product is square or irregularly block, not of uniform size.Surface palm fibre Brown or pitchy, smooth and slightly gloss.Matter is hard, and frangible, section is irregular, has gloss, has pore, wet to have erosion.Property Taste: bitter, puckery, is slightly cold.Gui Jing: return lung channel.Effect: hygroscopic myogenic sore.Cure mainly: for unhealing ulcer, eczema, aphtha, fall and flutter Grieved. traumatism and bleeding.Pharmacological action: 1. protect the liver, choleretic effect；2. resisting pathogenic microbes effect；3. suppress intestinal movement and resist Diarrhoea effect；4. hypoglycemic activity.

Radix cynanchi atrati: Ji Yuan: this product is the dry root and rhizome of Asclepiadaceae plant radix cynanchi atrati or Cynanchum versicolor Bunge.Chemical analysis: straight Vertical radix cynanchi atrati root is containing cynanchol, volatile oil, cardiac glycoside.Nature and flavor: bitter, salty, cold.Gui Jing: return stomach, liver, kidney channel.Effect: clearing heat and cooling blood, Inducing diuresis for treating strangurtia, detoxification sore treatment.Cure mainly: seeking heating, fever due to yin deficiency, hectic fever due to yin labor heat, fever caused by blood deficiency in postpartum for the evil wound of temperature, heat is drenched. Blood drenches, swollen ulcer drug.

Littleleaf dogwood root: Ji Yuan: for root or the branches and leaves of the Cornaceae little wood of Macrocarpium plant.The property of medicine: acid puckery, micro-, cool.Merit Can cure mainly: relieving superficies by cooling, hemostasis and anti-inflammation.

Cuttlebone: Ji Yuan: for Sepiidae animal sepiella maindroni de Rochebrune, prosperous cuttlefish, Sepia andreana, hickie cuttlefish, tiger class cuttlefish, intend mesh The inner casing of the multiple cuttlefish such as cuttlefish.Pharmacological action: 1. radiation resistance；2. promote bone defect healing effect.Nature and flavor: taste is salty；Puckery； Warm in nature.Gui Jing: liver；Kidney channel.Function cures mainly: astringing to arrest bleeding；Treating spontaneous emission and leukorrhagia；Relieving haperacidity pain relieving；Hygroscopic sore.Main haematemesis；Spitting blood；Collapse Leakage；Have blood in stool；Bleeding from five sense organs or subcutaneous tissue；Traumatic bleeding；Emission due to the kidney deficiency involuntary emission, leukorrhea with reddish discharge, have a stomachache noisy；Belch pantothenic acid；Eczema ulcer.

Ribbed value: Ji Yuan: for the herb of Vittariaceae plant ribbed value.Nature and flavor: bitter；Puckery；Cool.Gui Jing: the heart；Liver Channel.Merit Can cure mainly: wind and heat dispersing；Relaxing muscles and tendons pain relieving；Invigorating the spleen disappears infantile malnutrition due to digestive disturbances or intestinalparasites；Hemostasis.Main acute infantile convulsion wind；Mesh screen；Traumatic injury；Arthralgia due to wind-dampness；Little Youngster's infantile malnutrition due to digestive disturbances or intestinalparasites；Women's type of tubercular disease found in women；Spitting of blood；Spit blood.

Raspberry: Ji Yuan: for the immature fruit of rosaceous plant Rubus chingii, rubus coreanus etc..Chemical analysis: palm leaf Raspberry is containing organic acid, carbohydrate and a small amount of vitamin C.Nature and flavor: sweet acid are flat.Gui Jing: " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " enter liver, kidney two warp.” Function cures mainly: filling liver kidney, reduces just, supporing yang, controlling nocturnal emission with astringent drugs, improving eyesight.Control impotence, seminal emission, number of urinating, to lose and drown, consumptive disease, mesh is dark.

Sowthistle: Ji Yuan: for the herb of feverfew sowthistle.Pharmacological action: antitumor action.Sowthistle water boiling concentration Acute lymphoblastic type leukaemia, acute and chronic myelocytic leukemia patient's haemocyte dehydrogenase are had by alcoholic extract Obvious inhibiting effect.Nature and flavor: " Hebei Chinese medicine handbook ": " cold in nature, bitter." function cures mainly: clearing heat and detoxicating, qi-restoratives cough-relieving.Control bacterium Dysentery, laryngitis, weak cough, internal piles abjection, leukorrhea.

Sisal hemp: Ji Yuan: for the leaf of Agavaceae plants sisal hemp.Pharmacological action: the cloudy stagnant effect of neuro-muscular: sisal hemp is extracted Thing [be equivalent to 50-250mg(leaf)/ml] can first strengthen the contraction of chicken abdominal muscle neuro-muscular sample indirect induced, and then retardance is straight Connect or indirect stimulation effect causes tension force to continue but reversible change.Its effect similar depolarising SC, and different Galanthamine effect in non depolarization.Nature and flavor: sweet；Pungent；Cool.Function cures mainly: cooling blood and hemostasis；Subdhing swelling and detoxicating.Main tuberculosis is spat blood； Bleeding from five sense organs or subcutaneous tissue；Have blood in stool；Dysentery；Ulcerative carbuncle pyogenic infections；Hemorrhoid.

Peanut branchlet and leaf: Ji Yuan: for the cauline leaf of legume peanut.Chemical analysis: aerial part contains multiple volatilization Property composition, that has confirmed has 1-amylene-3 alcohol, hexanol, linalool, alpha-terpineol, geraniol.Possibly together with asafoetide in peanut leaf Acid, p-Coumaric Acid, aesculetin, caffeic acid, pinite, Isoquercitrin, soyasaponins and potassium nitrate.Pharmacological action: 1. only Blood effect；2. hypotensive effect；3. sedative-hypnotic effect；Nature and flavor: sweet light；Flat.Gui Jing: Liver Channel.Function cures mainly: clearing heat and detoxicating, rather God's step-down.Main traumatic injury, carbuncle sore tumefacting virus, insomnia, hypertension.

The clinical practice of the preparation (embodiment 5) of test example gained of the present invention Oncology patients postoperative medical treatment thyroid cancer:

That chooses my institute treatment in October ,-2015 in April, 2013 is diagnosed as thyroid cancer patients totally 390 example, wherein male sex's example Several 169 examples, women number of cases 221 example, the age, the mean age was 40 years old in 21-63 year；The course of disease was at 3 months-5 years, and all patients are equal It is diagnosed as thyroid cancer through Fine-needle Aspiration Cytology.Clinical manifestation: primary tumor equal position thyroid gland one leaf, 283 example single-shot knots Joint, 107 example multiple nodules, matter is hard or medium hardness, and mobility is poor, and how uneven surface is.This side thyroid gland of row is agreed to through patient Tumorectomy, postoperative have 270 example patients heart kidney-yin deficiency symptom occur, is embodied in: palpitation, malaise, spontaneous perspiration Night sweat, One's spirits are drooping, dry mouth and throat, dysphoria in chestpalms-soles, to have a dizzy spell, dysphagia, gas uncomfortable in chest suppresses, and body is become thin, and tongue is red, tongue Few, deep thready pulse is several.Giving 270 example patients and take medicine of the present invention, instructions of taking: three times a day, each 6-8 ball, warm water send Clothes, 20 days courses for the treatment of.Observe altogether and treat four courses for the treatment of.Curative effect determinate standard: recovery from illness: clinical symptoms, sign disappear or basic Disappear；Effective: clinical symptoms, sign are obviously improved；Effective: clinical symptoms, sign all take a favorable turn；Invalid: clinical symptoms are without bright Show and improve or increase the weight of.Total effective rate=(recovery from illness number of cases+effective number of cases+effective number of cases)/total inspection case load × 100%.Result is such as Shown in table 1.

The observation of curative effect of 270 example patients of medicine of the present invention taken by table 1

From the data in table 1, it can be seen that in the postoperative patient that heart kidney-yin deficiency occurs of 270 examples taking medicine of the present invention, 166 examples of fully recovering (61.5%), effective 83 examples (30.7%), effective 16 examples (5.9%), invalid 5 examples (1.9%), total effective rate is 98.1%.Data above Show, the preparation of Oncology patients of the present invention postoperative medical treatment thyroid cancer, various clinical symptom can be effectively improved, accelerate patient's health Multiple, significantly improve the quality of life of patient.

It should be pointed out that, the detailed description of the invention more representational example that is the present invention, it is clear that the skill of the present invention Art scheme is not limited to above-described embodiment, it is also possible to have many variations.Those of ordinary skill in the art, the most public with present invention institute What what that open or according to file written description was undoubted obtained, all it is considered as this patent scope of the claimed.

Claims

1. the preparation of Oncology patients postoperative medical treatment thyroid cancer, it is characterised in that be prepared from by following bulk drugs, all attach most importance to Amount part: Typhonium giganteum 15-26, japanese hylomecon root 6-18, black nightshade 3-8, common lantana flower 16-22, desmodium 4-11, catechu 3-6, radix cynanchi atrati 5- 10, littleleaf dogwood root 20-24, cuttlebone 7-12, ribbed value 17-21, raspberry 2-5, sowthistle 5-9, sisal hemp 18-22, peanut branch Leaf 6-10.

2. the preparation of Oncology patients postoperative medical treatment thyroid cancer as claimed in claim 1, it is characterised in that by following bulk drugs It is prepared from, is weight portion: Typhonium giganteum 18-23, japanese hylomecon root 10-14, black nightshade 4-7, common lantana flower 18-20, desmodium 6-9, Catechu 4-5, radix cynanchi atrati 6-9, littleleaf dogwood root 21-23, cuttlebone 8.5-10.5, ribbed value 18-20, raspberry 3-4, sowthistle 6-8, sword Fiber crops 19-21, peanut branchlet and leaf 7-9.

3. the preparation of Oncology patients postoperative medical treatment thyroid cancer as claimed in claim 1, it is characterised in that by following bulk drugs It is prepared from, is weight portion: Typhonium giganteum 20.5, japanese hylomecon root 12, black nightshade 5.5, common lantana flower 19, desmodium 7.5, catechu 4.5, Radix cynanchi atrati 7.5, littleleaf dogwood root 22, cuttlebone 9.5, ribbed value 19, raspberry 3.5, sowthistle 7, sisal hemp 20, peanut branchlet and leaf 8.

4. the preparation method of the preparation pill of the postoperative medical treatment of Oncology patients as described in claim 1-3 is arbitrary thyroid cancer, its Being characterised by, step is as follows:

The preparation method of pill the most according to claim 4, it is characterised in that step (3) crosses 80-140 mesh sieve (preferred mistake 100-120 mesh sieve, mistake 110 mesh sieve more preferably).

The preparation method of pill the most according to claim 4, it is characterised in that step (5) described auxiliary material is that mass fraction is The sucrose fine of 8.2% and mass fraction are the sodium cellulose glycolate of 2.3%.

7. the preparation method of the formulation tablet of the postoperative medical treatment of Oncology patients as described in claim 1-3 is arbitrary thyroid cancer, its Being characterised by, step is as follows:

The preparation method of tablet the most according to claim 7, it is characterised in that auxiliary material described in step (4) is that quality is divided Number be 8.6% dextrin fine powder and mass fraction be the stearic acid of 3.2%.

9. the preparation method of the preparation decoction of the postoperative medical treatment of Oncology patients as described in claim 1-3 is arbitrary thyroid cancer, its Being characterised by, step is as follows:

10. the preparation method of the preparation thick paste agent of the postoperative medical treatment of Oncology patients as described in claim 1-3 is arbitrary thyroid cancer, It is characterized in that, step is as follows: