CN105816547A - Method for preparing band-aid unguent - Google Patents

Method for preparing band-aid unguent Download PDF

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Publication number
CN105816547A
CN105816547A CN201610189631.1A CN201610189631A CN105816547A CN 105816547 A CN105816547 A CN 105816547A CN 201610189631 A CN201610189631 A CN 201610189631A CN 105816547 A CN105816547 A CN 105816547A
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vitamin
polymer substance
mass ratio
arbitrary proportion
substance solution
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CN201610189631.1A
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Chinese (zh)
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刘彬
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Individual
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4415—Pyridoxine, i.e. Vitamin B6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/57—Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A61K35/64—Insects, e.g. bees, wasps or fleas
    • A61K35/644—Beeswax; Propolis; Royal jelly; Honey
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534—Mentha (mint)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/738—Rosa (rose)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7015—Drug-containing film-forming compositions, e.g. spray-on

Abstract

The invention relates to a method for preparing band-aid unguent. The method includes the steps that high molecular substances and distilled water are added into a container in a certain mass ratio, heated to be at the temperature of 80 DEG C to 100 DEG C and stirred to be fully dissolved, and a high molecular substance solution is obtained; the high molecular substance solution, a broad spectrum bactericide, a moisturizing agent, a natural freshener and nutrient substances are mixed to be even in a certain mass ratio, and the band-aid unguent is obtained. The band-aid unguent is pasty, and has the advantages of being convenient to use and carry and good in treating effect.

Description

A kind of preparation method of adhesive bandage ointment
Technical field
The present invention relates to the preparation method of a kind of adhesive bandage, be specifically related to the preparation method of a kind of adhesive bandage ointment.
Background technology
Adhesive plaster poor air permeability used by adhesive bandage, the body local normocrinic steam of institute and perspiration can not penetrate this layer of adhesive plaster, then local skin be produced action of soaking, and the time one may cause the problems such as eczema, skin allergy for a long time.
Summary of the invention
It is desirable to provide the preparation method of a kind of adhesive bandage ointment, there is therapeutic effect good, easy to use, it is simple to the feature carried.
In order to achieve the above object, the present invention is by the following technical solutions:
The preparation method of a kind of adhesive bandage ointment, it is characterised in that follow the steps below:
Polymer substance and distilled water are joined in container according to certain mass ratio, it is heated to 80～100 DEG C, stirring is to being completely dissolved, obtain polymer substance solution, by polymer substance solution, wide-spectrum bactericide, wetting agent, natural freshener and nutrient substance according to certain mass than mix homogeneously, obtain adhesive bandage ointment.
The mass ratio of described polymer substance and distilled water is 5～15:85～95.
The mass ratio of described polymer substance solution, wide-spectrum bactericide, wetting agent, natural freshener and nutrient substance is 5～60:35～90:1～20:1～20:1～40.
Described polymer substance is the two or more of a kind of or arbitrary proportion in polyacrylamide, sodium polyacrylate, sodium alginate, guar gum, sodium carboxymethyl cellulose and polyvinyl alcohol；Described wetting agent is the two or more of a kind of or arbitrary proportion in glycerol, propylene glycol and sorbitol；Described wide-spectrum bactericide is the two or more of a kind of or arbitrary proportion in chlorhexidine acetate, chlorhexidine gluconate, benzalkonium chloride, tetracycline and chloromycetin；Described natural freshener is the two or more of a kind of or arbitrary proportion in Oleum menthae, menthol and Borneolum Syntheticum；Described nutrient substance is the two or more of a kind of or arbitrary proportion in Mel, vitamin C, vitamin A, vitamin B2, vitamin B6, vitamin E, rose ethereal oil and Ovum Gallus domesticus album.
The present invention has a following Advantageous Effects:
1, the present invention is paste, is applied directly to injury, easy to use, be easy to carry.
2, forming layer protecting film after the present invention smears, be protected by wound, protecting film is breathed freely
Property is good, will not intercept penetrating of moisture and antiperspirant gas, skin will not be caused allergy.
3, the present invention adds wetting agent, makes medicine keep long moisture state, profit after smearing
In the skin absorption to nutrient substance, and protecting film can be made soft, smooth.
4, the present invention adds natural freshener, and the volatilization smearing rear freshener can reduce the temperature in affected part
Degree, beneficially alleviating pain and hemostasis.
5, the present invention adds nutrient substance, and wound is carried out nutritional supplementation, beneficially injury region
Recover, it is to avoid scar.
Detailed description of the invention
In order to be more fully understood that and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
By polyacrylamide, sodium polyacrylate and distilled water join in container according to mass ratio 3:7:90, it is heated to 85 DEG C, stirring is to being completely dissolved, obtain polymer substance solution, by polymer substance solution, chlorhexidine acetate, chlorhexidine gluconate, benzalkonium chloride, tetracycline, chloromycetin, glycerol, propylene glycol, sorbitol, Oleum menthae, menthol, Mel, vitamin C, vitamin A, vitamin B2, vitamin B6, vitamin E, rose ethereal oil and Ovum Gallus domesticus album are according to mass ratio 15:15:10:10:10:5:3:2:1:1:2:1:7:1:2:1:7:2:5 mix homogeneously, it is concentrated into paste, obtain adhesive bandage ointment.
Embodiment 2
Polyvinyl alcohol, sodium polyacrylate, sodium alginate and distilled water are joined in container according to mass ratio 6:3:2:89, it is heated to 97 DEG C, stirring is to being completely dissolved, obtain polymer substance solution, by polymer substance solution, benzalkonium chloride, glycerol, propylene glycol, Oleum menthae, menthol, Mel, vitamin C, vitamin A, vitamin B2, vitamin B6, vitamin E, rose ethereal oil and Ovum Gallus domesticus album according to mass ratio 5:40:4:6:3:2:2:5:7:7:7:5:5:2 mix homogeneously, it is concentrated into paste, obtains adhesive bandage ointment.
Embodiment 3
By sodium alginate, sodium polyacrylate, sodium carboxymethyl cellulose and distilled water join in container according to mass ratio 2:7:3:88, it is heated to 90 DEG C, stirring is to being completely dissolved, obtain polymer substance solution, by polymer substance solution, chlorhexidine gluconate, benzalkonium chloride, tetracycline, sorbitol, menthol, dimethicone, Mel, vitamin C, vitamin A, vitamin B2, vitamin B6, vitamin E, rose ethereal oil and Ovum Gallus domesticus album are according to mass ratio 10:50:2:2:3:3:2:7:7:2:2:2:4:2:2 mix homogeneously, it is concentrated into paste, obtain adhesive bandage ointment.
Embodiment 4
Sodium alginate, sodium polyacrylate and distilled water are joined in container according to mass ratio 3:9:88, it is heated to 80 DEG C, stirring is to being completely dissolved, obtain polymer substance solution, by polymer substance solution, chlorhexidine acetate, benzalkonium chloride, propylene glycol, sorbitol, menthol, Mel, vitamin C, vitamin A, vitamin B2, vitamin B6, vitamin E, rose ethereal oil and Ovum Gallus domesticus album according to mass ratio 20:50:2:2:3:2:4:2:2:2:2:5:2:2 mix homogeneously, it is concentrated into paste, obtains adhesive bandage ointment.
Further illustrate below in conjunction with experimental data and the method have the benefit that
1, physical data
Big pharmacy, swallow wedding hall, streamside road, Fushan District, Yantai City, the big pharmacy of Kingcon, the sales situation of two kinds of pharmacy, three, the big pharmacy of health and happiness (common adhesive bandage, ointment of the present invention) adhesive bandage, between in May, 2014～in November, 2015, are added up by inventor.
2, statistical result is shown in Table 1
Table 1
Common adhesive bandage (box) Ointment of the present invention (box)
Big pharmacy, swallow wedding hall 126 687
The big pharmacy of Kingcon 130 598
The big pharmacy of health and happiness 97 579
Table 1 is this it appears that sales volume of the present invention is significantly more than traditional adhesive bandage, and investigation also finds that common adhesive bandage mostly is old people and buys, and ointment of the present invention is mainly Yong adult people and buys.
Within 5 months post sales, do satisfaction investigation, investigation statistics result such as table 2.
Table 2
Easy to use, be easy to carry Use rear untoward reaction Good results degree 2-->
Common adhesive bandage 34% 36% 38%
Ointment of the present invention 66% 0 62%
As can be seen from Table 2, product of the present invention using, carry, with after the aspect that has no adverse reaction be substantially better than conventional medicament, in terms of therapeutic effect, be also better than conventional medicament.
3, discuss
Severe trauma advises that timely medical check, in order to avoid delaying treatment, under wound not serious conditions, directly smears this product.

Claims (1)

1. the preparation method of an adhesive bandage ointment, it is characterised in that follow the steps below:
Joining in container by polymer substance and distilled water according to certain mass ratio, be heated to 80～100 DEG C, stirring, to being completely dissolved, obtains polymer substance solution；
1), by polymer substance solution, wide-spectrum bactericide, wetting agent, natural freshener and nutrient substance according to certain mass than mix homogeneously, be down to room temperature, obtain adhesive bandage ointment；
The mass ratio of described polymer substance and distilled water is 5～15:85～95；The mass ratio of described polymer substance solution, wide-spectrum bactericide, wetting agent, natural freshener and nutrient substance is 5～60:35～90:1～20:1～20:1～40；
Described polymer substance is the two or more of a kind of or arbitrary proportion in polyacrylamide, sodium polyacrylate, sodium alginate, guar gum, sodium carboxymethyl cellulose and polyvinyl alcohol；Described wide-spectrum bactericide is the two or more of a kind of or arbitrary proportion in chlorhexidine acetate, chlorhexidine gluconate, benzalkonium chloride, tetracycline and chloromycetin；Described wetting agent is the two or more of a kind of or arbitrary proportion in glycerol, propylene glycol and sorbitol；Described natural freshener is the two or more of a kind of or arbitrary proportion in Oleum menthae, menthol and Borneolum Syntheticum；Described nutrient substance is the two or more of a kind of or arbitrary proportion in Mel, vitamin C, vitamin A, vitamin B2, vitamin B6, vitamin E, rose ethereal oil and Ovum Gallus domesticus album.
CN201610189631.1A 2016-03-30 2016-03-30 Method for preparing band-aid unguent Withdrawn CN105816547A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610189631.1A CN105816547A (en) 2016-03-30 2016-03-30 Method for preparing band-aid unguent

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Application Number Priority Date Filing Date Title
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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101584721A (en) * 2009-07-06 2009-11-25 江苏泰灵生物科技有限公司 Chinese traditional medicine antibiotic hemostatic plaster
CN103341203A (en) * 2013-06-24 2013-10-09 张延海 Medical dressing, preparation method of medical dressing and preparation method of dressing plaster
CN105012960A (en) * 2014-04-16 2015-11-04 上海现代药物制剂工程研究中心有限公司 Film-forming gel composition, application and wound protecting material
CN204744613U (en) * 2015-07-17 2015-11-11 张辉海 Chinese mugwort grass woundplast
CN204864218U (en) * 2015-03-26 2015-12-16 南阳市汇博生物技术有限公司 Chitosan protects to create and applies ointment or plaster
CN105268017A (en) * 2015-10-16 2016-01-27 张自强 Technology for preparing quick hemostasis patch
CN105288721A (en) * 2015-10-16 2016-02-03 天津市顶硕科贸有限公司 Liquid band-aid and preparation technology thereof

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101584721A (en) * 2009-07-06 2009-11-25 江苏泰灵生物科技有限公司 Chinese traditional medicine antibiotic hemostatic plaster
CN103341203A (en) * 2013-06-24 2013-10-09 张延海 Medical dressing, preparation method of medical dressing and preparation method of dressing plaster
CN105012960A (en) * 2014-04-16 2015-11-04 上海现代药物制剂工程研究中心有限公司 Film-forming gel composition, application and wound protecting material
CN204864218U (en) * 2015-03-26 2015-12-16 南阳市汇博生物技术有限公司 Chitosan protects to create and applies ointment or plaster
CN204744613U (en) * 2015-07-17 2015-11-11 张辉海 Chinese mugwort grass woundplast
CN105268017A (en) * 2015-10-16 2016-01-27 张自强 Technology for preparing quick hemostasis patch
CN105288721A (en) * 2015-10-16 2016-02-03 天津市顶硕科贸有限公司 Liquid band-aid and preparation technology thereof

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